40
6
91
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T8599 |
Betazole dihydrochloride
盐酸倍他唑,Betazole hydrochloride |
Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
Betazole dihydrochloride (Betazole hydrochloride) 是吡唑类组胺,是一种口服活性 H2受体激动剂,能诱导胃酸分泌,导致胆总管压力立即显著升高。它作为一种诊断剂,用于研究胃酸分泌能力。 | |||
T2044 |
Varespladib
LY315920,伐瑞拉地,伐瑞拉迪 |
Phospholipase | Metabolism |
Varespladib (LY315920) 是选择性group IIA, secretory phospholipase A2(sPLA2)抑制剂,其IC50=9 nM。它对大鼠,兔,豚鼠和人等各种物种血清的sPLA2活性具有明显的抑制作用,IC50分别为 8.1 nM,5.0 nM,3.2 nM 和 6.2 nM。 | |||
T22665 |
PD 128042
CI 976 |
Acyltransferase | Metabolism |
PD 128042 (CI 976) 是口服有效的ACAT (酰基辅酶 A: 胆固醇酰基转移酶)选择性抑制剂。它也是LPAT(溶血磷脂酰基转移酶) 抑制剂。它抑制高尔基体相关 LPAT 活性 (IC50=15 μM)。它抑制多种膜运输步骤,包括在内吞和分泌途径中发现的步骤。 | |||
T6928 |
Pantoprazole
SKF96022,泮托拉唑,BY1023 |
Apoptosis; Proton pump; Autophagy | Apoptosis; Autophagy; Membrane transporter/Ion channel |
Pantoprazole (BY1023) 是一种质子泵抑制剂,用于短期治疗由胃食管反流病引起的食管糜烂和溃疡。它联合阿霉素可显著增加肿瘤生长延迟。它是一种取代的苯并咪唑,是H+/K+-ATPase 抑制剂,可改善 pH 值稳定性,具有抗分泌和抗溃疡的作用。 | |||
T0161 |
Pantoprazole Sodium Hydrate
SKF96022 sodium hydrate,泮托拉唑钠水合物,BY1023 (sodium hydrate),SKF96022 (sodium hydrate) |
Apoptosis; Potassium Channel; Proton pump; Autophagy | Apoptosis; Autophagy; Membrane transporter/Ion channel |
Pantoprazole Sodium Hydrate (BY1023 (sodium hydrate)) 是一种具有口服活性的质子泵抑制剂。它是取代的苯并咪唑,是H+/K+-ATPase 抑制剂。它可改善 pH 值稳定性,具有抗分泌和抗溃疡的作用。它联合阿霉素可显著增加肿瘤生长延迟。 | |||
T6929 |
Pantoprazole sodium
Pantecta,泮托拉唑钠盐,SKF96022 sodium,SKF96022 (sodium),BY1023 (sodium),泮托拉唑钠,BY-1023 sodium,Pantoloc |
Apoptosis; Others; Proton pump; HIF; Autophagy | Angiogenesis; Apoptosis; Autophagy; Chromatin/Epigenetic; Membrane transporter/Ion channel; Others |
Pantoprazole sodium (Pantecta) 是一种具有口服活性的质子泵抑制剂,是一种取代的苯并咪唑,是H+/K+-ATPase 抑制剂,IC50为 6.8 μM。它可以改善 pH 值稳定性,具有抗分泌和抗溃疡的作用。它联合阿霉素可显著增加肿瘤生长延迟。 | |||
T2486 |
IOWH-032
IOWH032,IOWH 032 |
CFTR; Autophagy | Autophagy; Membrane transporter/Ion channel |
IOWH-032 (IOWH032) 是一种合成 CFTR 抑制剂,可用于研究治疗霍乱、腹泻和分泌性腹泻,在T84和CHO-CFTR 细胞实验中IC50为1.01 uM。 | |||
T4192 |
hnps-PLA Inhibitor
|
Phospholipase; LTR | Immunology/Inflammation; Metabolism |
hnps-PLA Inhibitor 是人类非胰腺分泌型磷脂酶 A (hnps-PLA) 的抑制剂。 | |||
T17218 |
Varespladib methyl
A-002,LY333013 |
Others; Phospholipase | Metabolism; Others |
Varespladib methyl (LY333013) 是 Varespladib 的生物可利用前药,是一种特异性 II 组分泌型磷脂酶 A2 抑制剂。 | |||
T0594 |
Diphenmanil methylsulfate
Diphemanil mesylate,Diphemanil Methylsulfate,甲硫二苯马尼 |
AChR | Neuroscience |
Diphenmanil methylsulfate (Diphemanil mesylate) 是一种抗胆碱能季铵盐,可与毒蕈碱乙酰胆碱受体结合,从而减少胃酸、汗液和唾液的分泌。 | |||
T16865 |
SCH28080
|
ATPase; Proton pump | Membrane transporter/Ion channel |
SCH28080 是一种可逆且具有 K+ 竞争性的胃 H+/K+-ATP 酶 (H+/K+-ATPase) 抑制剂,IC50 值为 20 nM (家兔微粒体膜)。SCH28080 在体内是有效的酸分泌抑制剂,具有抗溃疡活性、抗分泌和细胞保护活性。 | |||
T1756 |
Ilaprazole sodium
IY-81149 sodium,艾普拉唑钠 |
Proton pump; TOPK | MAPK; Membrane transporter/Ion channel |
Ilaprazole sodium (IY-81149 sodium) 是一种具有口服活性质子泵抑制剂,以剂量依赖性方式不可逆地抑制 H+/K+-ATPase,在兔壁细胞制剂中的 IC50为 6 μM。它也是一种有效的 T 细胞起源蛋白激酶(TOPK)抑制剂,用于胃溃疡的研究。 | |||
T30290 |
Bam 1745
Bam1745,Pyroglutamyl peptide bam-1745,Bam-1745 |
Others | Others |
Bam 1745 is a significant adrenomedullary secretory vesicles component. | |||
T27539 |
Hexocyclium metilsulfate
AB803,AB-803,Traline,AB 803 |
Others | Others |
Hexocyclium metilsulfate has anti-gastric secretory effects in humans. | |||
T29056 |
UK-9040
UK9040,UK 9040 |
Others | Others |
UK-9040 inhibits gastric secretory. | |||
T10008 |
BTM-1086
|
Others | Others |
BTM-1086 is a potent gastric secretory inhibitor and an anti-ulcer agent. | |||
T23547 |
YM 26734
|
Others | Others |
Competitive inhibitor of secretory phospholipase A2 (sPLA2) | |||
T84972 |
LY433771
LSN433771 |
Others | Others |
LY433771 is a compound that inhibits the activity of Type X secretory phospholipase A2. | |||
T15672 | KU14R | Others | Others |
KU14R is a new I(3)-R antagonist, which selectively blocks the insulin secretory response to imidazolines. | |||
T20755 |
Trimegestone
RU27987,RU-27987,RU 27987 |
Others | Others |
Trimegestone, a highly effective oral progestogen, is used for endometrial protection, all doses inducing secretory endometrial transformation. | |||
T29288 |
163-BP3
|
Others | Others |
163-bp3 is an effective photoaffinity probe and can be used as a target γ Secretory enzyme. | |||
T68573 |
Tigapotide triflutate
|
Others | Others |
Tigapotide triflutate is a synthetic peptide corresponding to amino acids 31-45 of PSP94 (prostate secretory protein) that inhibits matrix metalloproteinase-9 secretion. | |||
T68574 |
Tigapotide Free Base
|
||
Tigapotide Free Base is a synthetic peptide corresponding to amino acids 31-45 of PSP94 (prostate secretory protein) that inhibits matrix metalloproteinase-9 secretion. | |||
T76538 |
Pancreatic polypeptide
|
||
Pancreatic polypeptide 是由胰腺内分泌的 PP 细胞所分泌的多肽,具有调节胰腺分泌功能、影响肝糖原储存及胃肠分泌的作用。 | |||
T30831 |
Cgp 43182
Cgp-43182,Cgp43182 |
Others | Others |
CGP 43182 is an effective inhibitor of group IIA secretory phospholipase A2 (Group IIA sPLA2) activity in vitro, which can be used to prevent the synergistic effect of pro-inflammatory genes stimulated by cytokines mediated by NFkappaB. | |||
T28331 |
PD 136450
Cam1189,PD136450,Cam-1189,PD-136450,Cam 1189 |
Others | Others |
Cholecystokinin type B receptor antagonist PD-136,450 is a partial secretory agonist in the stomach and a full agonist in the pancreas of the rat. Gastrin (cholecystokinin type B (CCK-B)) receptor antagonists may help to elucidate the physiological role o | |||
T41088 |
Diadenosine pentaphosphate pentalithium
|
Others | Others |
Diadenosine pentaphosphate pentalithium is an endogenous vasoactive purine dinucleotide, isolated from thrombocytes. It is a member of the diadenosine polyphosphates (ApnA, n=2–7) and is found in secretory vesicles of platelets, chromaffin cells, Torpedo synaptic terminals, and brain synaptosomes. | |||
T37309 |
Diadenosine pentaphosphate pentaammonium
|
Others | Others |
Diadenosine pentaphosphate pentaammonium, an endogenous vasoactive purine dinucleotide isolated from thrombocytes, is one component of the diadenosine polyphosphates (ApnA, n=2-7) family. These compounds are found in secretory vesicles, including those in platelets, chromaffin cells, Torpedo synaptic terminals, and brain synaptosomes[1][2]. | |||
T37310 |
Diadenosine pentaphosphate pentasodium
|
Others | Others |
Diadenosine pentaphosphate pentasodium, an endogenous vasoactive purine dinucleotide isolated from thrombocytes, serves as a key component of secretory vesicles in platelets, chromaffin cells, Torpedo synaptic terminals, and brain synaptosomes. This compound, along with other diadenosine polyphosphates (ApnA, n=2-7), plays a crucial role in physiological processes[1][2]. | |||
T39173 |
Varespladib sodium
LY315920 sodium,伐瑞拉迪钠;伐瑞拉地钠 |
Others | Others |
Varespladib sodium (LY315920 sodium) is a highly potent and selective inhibitor of group IIA secretory phospholipase A2 (sPLA2), with an IC50 of 9 nM. It demonstrates significant inhibitory activity against sPLA2 in serum samples from multiple species, including rat, rabbit, guinea pig, and human, with IC50 values of 8.1 nM, 5.0 nM, 3.2 nM, and 6.2 nM, respectively. | |||
T81183 |
Sec61-IN-5
|
Others | Others |
Sec61-IN-5 (Compound 16c)是一种Sec61抑制剂,在A549细胞中展现出细胞毒性(IC50: 0.27 nM),并且能够抑制Sec61依赖性分泌功能(IC50: 0.08 nM)。 | |||
T61265 |
Exo2
|
Others | Others |
Exo2 is a secretion inhibitor that hinders the trafficking of Shiga toxin from endosomes to the trans-Golgi network. It inhibits the exit of secretory cargo from the endoplasmic reticulum (ER) and disrupts the Golgi apparatus. Notably, Exo2 does not impact the morphology of the trans-Golgi network (TGN). Additionally, Exo2 has the ability to induce calcium-dependent exocytosis in permeabilized adrenal chromaffin cells [1] [2]. | |||
T76480 |
Amylin (1-37) (human)
|
||
Amylin (1-37) (human) (hIAPP (1-37)) 为胰岛β细胞分泌颗粒中的肽类激素,其C端经酰胺化处理,第2和第7个半胱氨酸残基间形成二硫键。 | |||
T76320 |
FIZZ-1 (32-51) (mouse)
|
||
FIZZ-1 (32-51) (mouse) 是一种富含半胱氨酸的分泌性蛋白,主要在过敏性气道炎症中被巨噬细胞、支气管上皮细胞及II型肺泡上皮细胞高度表达,具有对肺成纤维细胞的抗凋亡功能,广泛应用于过敏性肺炎的研究领域。 | |||
T72005 |
Betazole
Ametazole |
Others | Others |
Betazole (Ametazole) 为一种吡唑类组胺,具有口服活性,作为H2受体激动剂发挥作用。该化合物能诱导胃酸分泌并立即显著提高胆总管压力。Betazole 作为一种称为histalog的诊断剂,应用于评估胃酸分泌功能。 | |||
T74891 |
Apratoxin S4
|
Others | Others |
Apratoxin S4(Apra S4)是一种Sec61抑制剂,能够有效阻止分泌蛋白的共翻译转运进入内质网(ER)。它对flaviviruses类病毒显示出抗病毒效果,IC50值在0.46 nM至170 nM不等。此外,Apratoxin S4通过抑制多条血管生成通路,能够抑制视网膜血管细胞活化,适用于病毒感染、血管生成相关疾病和癌症的研究。 | |||
T38052 |
CRA-2059 TFA
|
Others | Others |
CRA-2059 is a highly specific and selective tryptase inhibitor, with a Ki of 620 pM for recombinant human tryptase-β (rHTβ)[1][2]. Tryptase is a trypsin-like serine protease found as a major protein component in human mast cell secretory granules. CRA-2059 has the potential for inflammatory bowel disease research[1]. [1]. Tremaine WJ, et al. Treatment of mildly to moderately active ulcerative colitis with a tryptase inhibitor (APC 2059): an open-label pilot study. Aliment Pharmacol Ther. 2002;16... | |||
T37331 |
Pyrrophenone
|
Others | Others |
The group IVA phospholipase A2 (PLA2), known as calcium-dependent cytosolic PLA2 (cPLA2), selectively releases arachidonic acid (AA) from membrane phospholipids, playing a central role in initiating the synthesis of prostaglandins (PGs) and leukotrienes (LTs). Pyrrophenone inhibits cPLA2α with an IC50 of 4.2 nM in enzyme assays and potently blocks the release of AA and the production of PGE2 and LTC4 in cells (IC50 = 24, 25, and 14 nM, respectively). Its action is reversible and selective, as py... | |||
T38051 |
CRA-2059 hydrochloride
|
Others | Others |
CRA-2059 hydrochloride is a highly specific and selective tryptase inhibitor, with a Ki of 620 pM for recombinant human tryptase-β (rHTβ)[1][2]. Tryptase is a trypsin-like serine protease found as a major protein component in human mast cell secretory granules. CRA-2059 hydrochloride has the potential for inflammatory bowel disease research[1]. [1]. Tremaine WJ, et al. Treatment of mildly to moderately active ulcerative colitis with a tryptase inhibitor (APC 2059): an open-label pilot study. Ali... | |||
T38286 |
C26 Sphingomyelin (d18:1/26:0)
C26 Sphingomyelin (d18:1/26:0) |
Others | Others |
C26 Sphingomyelin is a sphingolipid that has been found in serum and cell or brain extracts.1,2,3C26 sphingomyelin levels are increased in the serum of patients with hemophagocytic lymphohistiocytosis, an inflammatory condition characterized by excessive immune activation.3C26 sphingomyelin has been used a component of monolayers to study the influence of sphingomyelin acyl chain length on sphingomyelin-sterol interactions.4[Matreya, LLC.] 1.Wang, J.-R., Zhang, H., Yau, L.D., et al.Improved sphi... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T13206 |
Tris(2,4-di-tert-butylphenyl)phosphate
|
Phospholipase | Metabolism |
Tris(2,4-di-tert-butylphenyl)phosphate 是一种从 Vitex negundoL 中分离的活性化合物,能够通过分子对接抑制了分泌性磷脂酶 A2(sPLA2),具有抗炎作用。 | |||
TN1419 |
Rhamnetin
beta-Rhamnocitrin,鼠李素 |
Others; Phospholipase | Metabolism; Others |
Rhamnetin (beta-Rhamnocitrin) 是一种槲皮素衍生物,在芫荽中被发现,具有抗氧化和抗炎活性。Rhamnetin 可抑制分泌型磷脂酶 A2。 | |||
TCS1772 |
Dehydroabietic acid
Dehydroabietate,脱氢松香酸 |
Antifection | Microbiology/Virology |
Dehydroabietic acid (Dehydroabietate) 是 EBV-EA 活化抑制剂。 它是食物衍生化合物,可通过降低血浆葡萄糖、胰岛素水平、血浆甘油三酯 (TG) 和肝 TG 水平来治疗肥胖相关疾病。它的衍生物在动物模型中表现出抗分泌和抗胃蛋白酶作用。 | |||
TN5221 | (-)-Variabilin | ||
Variabilin, a novel inhibitor of human platelet aggregation, it is a potent RGD (Arg-Gly-Asp)-containing antagonist of the fibrinogen receptor glycoprotein IIb-IIIa (GPIIb-IIIa; αIIbβ3) and the vitronectin receptor αvβ3.Variabilin is also an antimicrobial furanosesterterpene. Variabilin is an inhibitor of human secretory and cytosolic phospholipase A2 (PLA2) activities that controls eicosanoid production in vitro and in vivo, inhibits neutrophil degranulation and superoxide generation in vitro a... | |||
TN4659 |
Nimbin
|
COX | Immunology/Inflammation; Neuroscience |
Nimbin is an anti-pyretic, can be used to treat arthritis, hypoglycaemia, peptic ulcers, anti-secretory activity, and it can also be used as an antibiotic. Nimbin requires to elicit a 50% inhibition of this steroid hydroxylase activity in the three insect | |||
T75540 |
Ipomoeassin F
|
Others | Others |
Ipomoeassin F 是一种高效且具有选择性的内质网(ER)蛋白转位抑制剂,它通过作用于ER膜上的Sec61复合物(Sec61α)的成孔亚基来实现其功能。此化合物能特异性抑制SARS-CoV-2蛋白在ER膜上的转位,同时阻碍分泌蛋白和I型跨膜蛋白(TMP)的ER转运,但对III型TMP的转运不产生影响。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-03309 |
PLA2G10 Protein, Rat, Recombinant (His & Myc)
Phosphatidylcholine 2-acylhydrolase 10,Group 10 secretor... |
Rat | E. coli |
PLA2G10 Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 21.4 kDa and the accession number is Q9QZT3. | |||
TMPH-01177 |
CRISPLD2 Protein, Human, Recombinant (His & Myc)
CRISP11,LCCL domain-containing cysteine-rich secretory |
Human | HEK293 Cells |
CRISPLD2 Protein, Human, Recombinant (His & Myc) is expressed in HEK293. | |||
TMPH-02893 |
SVS4 Protein, Mouse, Recombinant (His & Myc)
Seminal vesicle protein 2,Seminal vesicle secretory... |
Mouse | E. coli |
N/A. SVS4 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 17.8 kDa and the accession number is P18419. | |||
TMPH-02690 |
PLA2G10 Protein, Mouse, Recombinant (His & Myc)
Pla2g10,Group X secretory phospholipase A2,Phosphat... |
Mouse | E. coli |
Secretory calcium-dependent phospholipase A2 that primarily targets extracellular phospholipids. Hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids with preference for phosphatidylcholines and phosphatidylglycerols over phosphatidylethanolamines. Preferentially releases sn-2 omega-6 and omega-3 polyunsaturated fatty acyl (PUFA) chains over saturated fatty acyls. Contributes to phospholipid remodeling of very low-density lipoprotein (VLDL), low-density li... | |||
TMPH-01316 |
ECM1 Protein, Human, Recombinant (GST & His & Myc)
Extracellular matrix protein 1,ECM1,Secretory compo... |
Human | E. coli |
Involved in endochondral bone formation as negative regulator of bone mineralization. Stimulates the proliferation of endothelial cells and promotes angiogenesis. Inhibits MMP9 proteolytic activity. ECM1 Protein, Human, Recombinant (GST & His & Myc) is expressed in E. coli expression system with N-10xHis-GST and C-Myc tag. The predicted molecular weight is 52.4 kDa and the accession number is Q16610. | |||
TMPH-02989 |
ESAT-6 Protein, Mycobacterium bovis, Recombinant (His & Myc)
ESAT-6,6 kDa early secretory antigenic target,esxA |
Mycobacterium bovis | E. coli |
A secreted protein. Acts as a strong host T-cell antigen. Plays a number of roles in modulating the host's immune response to infection as well as being responsible for bacterial escape into the host cytoplasm. ESAT-6 Protein, Mycobacterium bovis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 17.2 kDa and the accession number is P0A565. | |||
TMPH-02892 |
SCAMP4 Protein, Mouse, Recombinant (His)
Secretory carrier-associated membrane protein 4,Sca... |
Mouse | E. coli |
Probably involved in membrane protein trafficking. SCAMP4 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 26.9 kDa and the accession number is Q9JKV5. | |||
TMPY-00449 |
CRISP1 Protein, Mouse, Recombinant (His)
AW324342,cysteine-rich secretory protein 1,Aeg1,CRI... |
Mouse | HEK293 Cells |
CRISP1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.1 kDa and the accession number is Q03401. | |||
TMPY-04132 |
CRISP1 Protein, Mouse, Recombinant (hFc)
Aeg1,CRISP-1,AW324342,cysteine-rich secretory prote... |
Mouse | HEK293 Cells |
CRISP1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52.4 kDa and the accession number is Q03401. | |||
TMPH-02691 |
PLA2G12A Protein, Mouse, Recombinant (His & Myc)
Pla2g12a,Group XIIA secretory phospholipase A2,Phos... |
Mouse | Baculovirus Insect Cells |
PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. Does not exhibit detectable activity toward sn-2-arachidonoyl- or linoleoyl-phosphatidylcholine or -phosphatidylethanolamine. PLA2G12A Protein, Mouse, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 22.6 kDa and the accession number is Q9EPR2. | |||
TMPH-02071 |
PLA2R1 Protein, Human, Recombinant (His & Myc)
Secretory phospholipase A2 receptor,M-type receptor... |
Human | Baculovirus Insect Cells |
PLA2R1 Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus. | |||
TMPH-02070 |
PLA2R1 Protein, Human, Recombinant (His)
Secretory phospholipase A2 receptor,PLA2R1,C-type l... |
Human | E. coli |
PLA2R1 Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPH-03629 |
TES-26 Protein, Toxocara canis, Recombinant (His)
26 kDa secreted antigen,TES-26,Toxocara excretory-secret... |
Toxocara canis | P. pastoris (Yeast) |
Binds phosphatidylethanolamine. TES-26 Protein, Toxocara canis, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 27.9 kDa and the accession number is P54190. | |||
TMPH-01092 |
CHGA Protein, Human, Recombinant (His)
SP-I,Pituitary secretory protein I,CHGA,CgA,Chromog... |
Human | P. pastoris (Yeast) |
CHGA Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 50.9 kDa and the accession number is P10645. | |||
TMPY-05214 |
CRISP3 Protein, Human, Recombinant (His)
SGP28,CRS3,CRISP-3,cysteine-rich secretory protein ... |
Human | HEK293 Cells |
CRISP3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.9 kDa and the accession number is P54108.1. | |||
TMPH-00101 |
PDLP7 Protein, Arabidopsis thaliana, Recombinant (His & SUMO)
PDLP7,Cysteine-rich repeat secretory protein 60,Pla... |
Arabidopsis thaliana | E. coli |
Modulates cell-to-cell trafficking. PDLP7 Protein, Arabidopsis thaliana, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 41.3 kDa and the accession number is Q0WPN8. | |||
TMPH-03630 |
TES-26 Protein, Toxocara canis, Recombinant (His & SUMO)
26 kDa secreted antigen,Toxocara excretory-secretory |
Toxocara canis | E. coli |
Binds phosphatidylethanolamine. TES-26 Protein, Toxocara canis, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 41.9 kDa and the accession number is P54190. | |||
TMPH-01779 |
RNASE2 Protein, Human, Recombinant (His)
Ribonuclease US,Eosinophil-derived neurotoxin,Non-secret... |
Human | E. coli |
This is a non-secretory ribonuclease. It is a pyrimidine specific nuclease with a slight preference for U. Cytotoxin and helminthotoxin. Selectively chemotactic for dendritic cells. Possesses a wide variety of biological activities. RNASE2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 19.5 kDa and the accession number is P10153. | |||
TMPJ-00691 |
ZG16 Protein, Human, Recombinant (His)
Zymogen Granule Protein 16,ZG16,Zymogen Granule Membrane Pro... |
Human | HEK293 Cells |
Zymogen Granule Membrane Protein 16 (ZG16) belongs to the jacalin lectin family. ZG16 is highly expressed in liver and is detected at lower levels in colon, ileum and jejunum. ZG16 may play a role in protein trafficking. In addition, ZG16 may act as a linker molecule between the submembranous matrix on the luminal side of zymogen granule membrane (ZGM) and aggregated secretory proteins during granule formation in the TGN. | |||
TMPH-03108 |
GPX5 Protein, Pig, Recombinant (E. coli, His & Myc)
GPX5,Glutathione peroxidase 5,Epididymis-specific glutathion... |
Sus scrofa (Pig) | E. coli |
May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids. Since the purified porcine enzyme has very little activity towards hydrogen peroxide or organic hydroperoxides the protective effect is not likely to be exerted by its enzymatic activity. Instead, may protect sperm from premature acrosome reaction in the epididymis by binding to lipid peroxides, which might otherwise interact with phospholipase A2 and induce the acrosome reaction. GPX... | |||
TMPH-03109 |
GPX5 Protein, Pig, Recombinant (His & Myc)
GPX5,Epididymis-specific glutathione peroxidase-like protein... |
Sus scrofa (Pig) | P. pastoris (Yeast) |
May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids. Since the purified porcine enzyme has very little activity towards hydrogen peroxide or organic hydroperoxides the protective effect is not likely to be exerted by its enzymatic activity. Instead, may protect sperm from premature acrosome reaction in the epididymis by binding to lipid peroxides, which might otherwise interact with phospholipase A2 and induce the acrosome reaction. GPX... | |||
TMPH-01296 |
GPX5 Protein, Human, Recombinant (GST & His)
GPX5,Glutathione peroxidase 5,Epididymal secretory ... |
Human | E. coli |
Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids. | |||
TMPH-02891 |
SCGB3A2 Protein, Mouse, Recombinant (GST & His)
Uteroglobin-related protein 1,Secretoglobin family 3A member... |
Mouse | E. coli |
SCGB3A2 Protein, Mouse, Recombinant (GST & His) is expressed in E. coli expression system with N-6xHis-GST tag. The predicted molecular weight is 43.2 kDa and the accession number is Q920H1. | |||
TMPH-02820 |
GP2 Protein, Mouse, Recombinant (His)
Gp2,Pancreatic zymogen granule membrane protein GP-2,Pancrea... |
Mouse | P. pastoris (Yeast) |
GP2 Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 59.0 kDa and the accession number is Q9D733. | |||
TMPH-02821 |
GP2 Protein, Mouse, Recombinant (E. coli, His)
Pancreatic secretory granule membrane major glycopr... |
Mouse | E. coli |
GP2 Protein, Mouse, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 63.0 kDa and the accession number is Q9D733. | |||
TMPJ-00733 |
SPINK1 Protein, Human, Recombinant (His)
PSTI,Pancreatic Secretory Trypsin Inhibitor,TATI,Se... |
Human | HEK293 Cells |
Serine Protease Inhibitor Kazal-Type 1 (SPINK1) is a trypsin inhibitor that prevent the trypsin-catalyzed premature activation of zymogens within the pancreas. Defects in SPINK1 are a cause of pancreatitis (PCTT). A disease characterized by the presence of calculi in pancreatic ducts. It causes severe abdominal pain attacks. Defects in SPINK1 are the cause of susceptibility to tropical calcific pancreatitis (TCP). Recombinant SPINK1 protein (rSPINK1) stimulated cell proliferation in benign RWPE ... | |||
TMPH-02897 |
SPINK1 Protein, Mouse, Recombinant (His)
Serine protease inhibitor Kazal-type 3,Serine protease inhib... |
Mouse | P. pastoris (Yeast) |
Serine protease inhibitor which exhibits anti-trypsin activity. In the pancreas, protects against trypsin-catalyzed premature activation of zymogens.; In the male reproductive tract, binds to sperm heads where it modulates sperm capacitance by inhibiting calcium uptake and nitrogen oxide (NO) production. SPINK1 Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 8.1 kDa and the accession number is P09036. | |||
TMPJ-01283 |
UGRP1 Protein, Human, Recombinant
Uteroglobin-Related Protein 1,Secretoglobin Family 3A Member... |
Human | E. coli |
Uteroglobin-Related Protein 1 (UGRP1) belongs to the secretoglobin family which has been suggested to play a role in lung inflammation and allergic diseases. UGRP1 is a 17 kDa secreted homodimeric protein that shows amino acid sequence similarity with uteroglobin. UGRP1 is expressed predominantly in the lung and low levels of expression are detected in the thyroid. Expression of UGRP1 in lung epithelial cells is enhanced by IL-10 and decreased through the activities of IL-9 and IL-5. UGRP1 inter... | |||
TMPH-01916 |
PIP Protein, Human, Recombinant (His)
gp17,Secretory actin-binding protein,Gross cystic d... |
Human | E. coli |
PIP Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPH-01130 |
C1QTNF3 Protein, Human, Recombinant (His & Myc)
Secretory protein CORS26,Collagenous repeat-contain... |
Human | Baculovirus Insect Cells |
C1QTNF3 Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus. | |||
TMPH-02598 |
C1QTNF3 Protein, Mouse, Recombinant (His)
Secretory protein CORS26,C1QTNF3,Complement C1q tum... |
Mouse | HEK293 Cells |
C1QTNF3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with N-10xHis tag. The predicted molecular weight is 26.6 kDa and the accession number is Q9ES30. | |||
TMPH-01129 |
C1QTNF3 Protein, Human, Recombinant (His)
C1QTNF3,CORS26,Collagenous repeat-containing sequence 26 kDa... |
Human | E. coli |
C1QTNF3 Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPJ-00006 |
CXCL1 Protein, Mouse, Recombinant (His)
Scyb1,Growth-regulated α,Mgsa,Gro1,Growth-regulated alpha pr... |
Mouse | HEK293 Cells |
Growth-regulated alpha protein (CXCL1,KC), is a member of the alpha chemokine subfamily, was initially identified as an immediate early gene induced in mouse fibroblasts by platelet-derived growth factor. The N-terminal processed form KC(5-72) of the protein is produced by proteolytic cleavage after secretion from bone marrow stromal cells, and shows a highly enhanced hematopoietic activity. Mouse KC shows approximately 63% identity to that of mouse MIP-2. KC is also approximately 60% identical ... | |||
TMPJ-00835 |
FGF-4 Protein, Mouse, Recombinant
HSTF1,HST-1,FGF4,FGF-4,HBGF-4,Fibroblast growth factor 4,HST... |
Mouse | E. coli |
Fibroblast growth factor 4(FGF-4) is a heparin binding member of the FGF family. The human FGF4 cDNA encodes 206 amino acids (aa) with a 33 aa signal sequence and a 173 aa mature protein with an FGF homology domain that contains a heparin binding region near the C-terminus. Mature human FGF4 shares 91%, 82%, 94% and 91% aa identity with mouse, rat, canine and bovine FGF4, respectively. Human FGF-4 has been shown to exhibit cross species activity. Expression of FGF-4 and its receptors, FGF R1c, 2... | |||
TMPJ-00009 |
CCL2 Protein, Human, Recombinant
C-C motif chemokine 2,MCAF,CCL2,MCP-1,Monocyte chemotactic p... |
Human | E. coli |
The chemokine (C-C motif) ligand 2 (CCL2), also known as monocyte chemoattractant protein (MCP)-1 and small inducible cytokine A2 (SCYA2)), is a small cytokine that belongs to the CC chemokine family responsible for monocyte attraction. Its cognate receptor, CCR2, play a critical role in regulating nociceptive processes during neuropathic pain. Both CCL2 and CCR2 are implicated in induction of autoimmunity. CCL2 recruits monocytes, memory T cells, and dendritic cells to the sites of inflammation... | |||
TMPJ-00014 |
Resistin Protein, Human, Recombinant (His)
Resistin,C/EBP-epsilon-regulated myeloid-specific secreted c... |
Human | E. coli |
Resistin known as adipose tissue-specific secretory factor (ADSF) or C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein (XCP1) that seems to suppress insulin ability to stimulate glucose uptake into adipose cells. The length of the resistin pre-peptide in human is 108 amino acid residues and in the mouse and rat it is 114 aa; the molecular weight is ~12.5 kDa. Resistin is a cytokine whose physiologic role has been the subject of much controversy regarding its involvement wit... | |||
TMPJ-00670 |
YKT6 Protein, Human, Recombinant (His)
YKT6,Synaptobrevin homolog YKT6 |
Human | E. coli |
Synaptobrevin Homolog YKT6 (YKT6) is an enzyme that belongs to the Synaptobrevin family. YKT6 contains a longin domain and a v-SNARE coiled-coil homology domain. YKT6 is highly conserved from yeast to human and it can functionally complement the loss of the yeast homolog in the yeast secretory pathway. It is a membrane associated, isoprenylated protein that functions at the endoplasmic reticulum-Golgi transport step. YKT6 is considered as one of the SNARE recognition molecules implicated in vesi... | |||
TMPK-01201 |
BPIFA1/LUNX Protein, Human, Recombinant
Lung-specific protein X,BPI fold-containing family A member ... |
Human | E. coli |
Bactericidal/permeability-increasing fold containing family A, member 1 (BPIFA1) is a secretory protein found in human upper aerodigestive tract mucosa. This innate material is secreted in mucosal fluid or found in submucosal tissue in the human soft palate, lung, uvula, and nasal cavity. BPIFA1 is a critical component of the innate immune response that prevents upper airway diseases. | |||
TMPH-00791 |
NsLTP Protein, Helianthus annuus, Recombinant (His & Myc)
Non-specific lipid-transfer protein,SDI-9 |
Helianthus annuus | E. coli |
Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues. NsLTP Protein, Helianthus annuus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 16.4 kDa and the accession number is Q39950. | |||
TMPK-00649 |
CDH6 Protein, Cynomolgus, Recombinant (His)
Cadherin6,Cadherin-6,CDH6,CAD6,KCAD,K-cadherin |
Cynomolgus | HEK293 Cells |
Cadherin 6 (CDH6) is an adhesion molecule localizing to the endometrial luminal epithelial cell surface in the mid-secretory/receptive phase and knockdown of CDH6 in the Ishikawa cells (receptive endometrial epithelial cell line) compromises cell integrity. | |||
TMPH-02502 |
LRPAP1 Protein, Mouse, Recombinant (His & Myc)
Heparin-binding protein 44,Alpha-2-macroglobulin receptor-as... |
Mouse | Baculovirus Insect Cells |
Molecular chaperone for LDL receptor-related proteins that may regulate their ligand binding activity along the secretory pathway. LRPAP1 Protein, Mouse, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 18.2 kDa and the accession number is P55302. | |||
TMPH-01293 |
ERP29 Protein, Human, Recombinant (GST)
Endoplasmic reticulum resident protein 31,Endoplasmic reticu... |
Human | E. coli |
Does not seem to be a disulfide isomerase. Plays an important role in the processing of secretory proteins within the endoplasmic reticulum (ER), possibly by participating in the folding of proteins in the ER. | |||
TMPY-02181 |
PLA2G12B Protein, Mouse, Recombinant (His)
Fksg71,2010002E04Rik,Pla2g13,hlb218,phospholipase A2, group ... |
Mouse | HEK293 Cells |
Group XIIB secretory phospholipase A2-like protein, also known as Group XIII secretory phospholipase A2-like protein, GXIII sPLA2-like, sPLA2-GXIIB, GXIIB, PLA2G13 and PLA2G12B, is a secreted protein that belongs to the phospholipase A2 family. PLA2G12B / PLA2G13 is strongly expressed in liver, small intestine and kidney. Mammalian secretory phospholipase A2s ( sPLA2s ) form a family of structurally related enzymes that are involved in a variety of physiological and pathological processes via th... | |||
TMPJ-00381 |
PIGR Protein, Human, Recombinant (hFc)
Polymeric Immunoglobulin Receptor,Poly-Ig Receptor,Hepatocel... |
Human | HEK293 Cells |
PIGR binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment. | |||
TMPH-00304 |
SV2A Protein, Bovine, Recombinant (His & Myc)
Synaptic vesicle glycoprotein 2A,p87,SV2A |
Bovine | HEK293 Cells |
Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles. SV2A Protein, Bovine, Recombinant (His & Myc) is expressed in HEK293 mammalian cells with N-10xHis and C-Myc tag. The predicted molecular weight is 22.8 kDa and the accession number is Q29397. | |||
TMPK-00924 |
SLPI Protein, Mouse, Recombinant (hFc)
WAP4,BLPI,SLPI,HUSI-1,HUSI,MPI,ALP,WFDC4,ALK1 |
Mouse | HEK293 Cells |
Elafin and SLPI (secretory leucocyte protease inhibitor) have multiple important roles both in normal homoeostasis and at sites of inflammation. These include antiprotease and antimicrobial activity as well as modulation of the response to LPS (lipopolysaccharide) stimulation. Elafin and SLPI are members of larger families of proteins secreted predominantly at mucosal sites, and have been shown to be modulated in multiple pathological conditions. SLPI Protein, Mouse, Recombinant (hFc) is express... | |||
TMPH-03085 |
LTP2 Protein, Parietaria judaica, Recombinant (His & SUMO)
Allergen Par j II,Probable non-specific lipid-transfer prote... |
Parietaria judaica | E. coli |
Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues. LTP2 Protein, Parietaria judaica, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 27.3 kDa and the accession number is P55958. | |||
TMPH-02450 |
MALD3 Protein, Malus domestica, Recombinant (His & SUMO)
Non-specific lipid-transfer protein,MALD3 |
Apple | E. coli |
Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues. MALD3 Protein, Malus domestica, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 25.1 kDa and the accession number is Q9M5X7. | |||
TMPH-02824 |
Perforin-1/PRF1 Protein, Mouse, Recombinant (His)
Lymphocyte pore-forming protein,Cytolysin,Perforin-1,Prf1 |
Mouse | E. coli |
Plays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells. Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores. Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes. | |||
TMPJ-01173 |
TFF3 Protein, Mouse, Recombinant (His)
Itf,Trefoil factor 3,Intestinal trefoil factor,mITF,Tff3 |
Mouse | HEK293 Cells |
Trefoil factors (TFF) are secretory products of mucin producing cells. They play a key role in the maintenance of the surface integrity of oral mucosa and enhance healing of the gastrointestinal mucosa by a process called restitution. TFF comprises the gastric peptides (TFF1), spasmolytic peptide (TFF2), and the intestinal trefoil factor (TFF3). They have an important and necessary role in epithelial restitution within the gastrointestinal tract. Members of the trefoil family are characterized b... | |||
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