|
TMPK-01393
|
Tenascin Protein, Mouse, Recombinant (His)
Hexabrachion,Hxb,TN-C,TN,TNC,Tenascin-C
|
Mouse
|
HEK293 Cells
|
|
Tenascin-C (TNC) is a hexameric, multimodular extracellular matrix protein with several molecular forms that are created through alternative splicing and protein modifications. It is highly conserved amongst vertebrates, and molecular phylogeny indicates that it evolved before fibronectin. Tenascin-C has many extracellular binding partners, including matrix components, soluble factors and pathogens; it also influences cell phenotype directly through interactions with cell surface receptors. Tena... |
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TMPK-01392
|
Tenascin Protein, Human, Recombinant (His)
Tenascin-C,TNC,TN,Hexabrachion,Hxb,TN-C
|
Human
|
HEK293 Cells
|
|
Tenascin-C (TNC) is a hexameric, multimodular extracellular matrix protein with several molecular forms that are created through alternative splicing and protein modifications. It is highly conserved amongst vertebrates, and molecular phylogeny indicates that it evolved before fibronectin. Tenascin-C has many extracellular binding partners, including matrix components, soluble factors and pathogens; it also influences cell phenotype directly through interactions with cell surface receptors. Tena... |
|
TMPK-00942
|
DLK1 Protein, Mouse, Recombinant (His)
DLK1,DLK,pG2,secredeltin,ZOG,Pref1,DLK-1,FA1
|
Mouse
|
HEK293 Cells
|
|
paternally inherited genetic defects of DLK1 were identified in four families with nonsyndromic CPP and a metabolic phenotype. DLK1 encodes a transmembrane protein that is important for adipose tissue homeostasis and neurogenesis and is located in the imprinted chromosome 14q32 region associated with Temple syndrome. DLK1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 30.9 kDa and the accession number is Q09163-1. |
|
TMPY-00322
|
DEC-205 Protein, Human, Recombinant (His)
GP200-MR6,CD205,CLEC13B,lymphocyte antigen 75,LY-75,DEC-205
|
Human
|
HEK293 Cells
|
|
LY75 (Lymphocyte Antigen 75) is a Protein Coding gene. It is broadly expressed in the lymph node, appendix, and other tissues. LY75 knockdown in SKOV3 cells resulted in predominant upregulation of functional pathways implicated in cell proliferation and metabolism, while pathways associated with cell signaling and adhesion, complement activation, and immune response were mostly suppressed. Moreover, LY75 suppression had an opposite effect on EOC cell lines with the epithelial phenotype (A2780s a... |
|
TMPY-02481
|
ACOX1 Protein, Human, Recombinant (His)
PALMCOX,ACOX,SCOX,acyl-CoA oxidase 1, palmitoyl
|
Human
|
Baculovirus Insect Cells
|
|
Peroxisomal acyl-coenzyme A oxidase 1(ACOX1 or AOX) is the first enzyme of the fatty acid beta-oxidation pathway and belongs to the Acyl-CoA oxidase family. Human liver peroxisomes contain two acyl-CoA oxidases, namely, palmitoyl-CoA oxidase (ACOX1/AOX) and a branched chain acyl-CoA oxidase. The palmitoyl-CoA oxidase (ACOX1/AOX) oxidizes the CoA esters of straight chain fatty acids and prostaglandins and donates electrons directly to molecular oxygen, thereby producing H2O2. Human ACOX1/AOX is a... |
|
TMPY-00117
|
FGF-16 Protein, Human, Cynomolgus, Recombinant
fibroblast growth factor 16
|
Human,Cynomolgus
|
Baculovirus Insect Cells
|
|
Fibroblast growth factor 16 (FGF16) is preferentially expressed in the heart after birth, suggesting its regulation is associated with tissue-specific chromatin remodeling and DNA-protein interactions. Mutation of the MEF2 site resulted in a blunting of FGF16 promoter activity in transfected neonatal rat cardiac myocytes, that chromatin remodeling and MEF2 binding in the FGF16 promoter contribute to expression in the postnatal heart. FGF16 involvement in the fine tuning of the human skeleton of ... |
|
TMPJ-00037
|
FGF-2 Protein, Mouse, Recombinant
Fibroblast Growth Factor 2,bFGF,HBGF-2,Basic Fibroblast Grow...
|
Mouse
|
E. coli
|
|
FGF basic is one of 22 mitogenic proteins of the FGF family, which show 35-60% amino acid conservation. Unlike other FGFs, FGF acidic and basic lack signal peptides and are secreted by an alternate pathway. The 17 kDa mouse sequence has 98% aa identity with rat, and 95% identity with human, bovine, and sheep FGF basic. Binding of FGF to heparin or cell surface HSPG is necessary for binding, dimerization and activation of tyrosine kinase FGF receptors. FGF basic binds other proteins, polysacchari... |
|
TMPK-01467
|
HLA-A*02:01&B2M&HPV 16 E6 (KLPQLCTEL) Monomer Protein, Human, MHC (His & Avi)
HPV16,E6,Human papillomavirus type 16
|
Human
|
HEK293 Cells
|
|
Human papillomavirus (HPV) 16 infection is a necessary condition for the pathogenesis and development of cervical cancer. The E6 protein is expressed by the HPV16 E6 gene and promotes malignant phenotype transformation, which is an important mechanism for the occurrence and development of cervical cancer. |
|
TMPK-00358
|
CD229 Protein, Human, Recombinant (His & Avi), Biotinylated
T100,Lgp100,LY9,AI893573,CD229,SLAMF3
|
Human
|
HEK293 Cells
|
|
CD229 was strongly and homogeneously overexpressed on the PC of patients with monoclonal gammopathy of undetermined significance (MGUS), smoldering myeloma, MM, and PC leukemia. CD229 was particularly overexpressed on those PC showing an abnormal phenotype such as expression of CD56. Most importantly, CD229 was also highly expressed on those cells in the patients' BM displaying the phenotype of chemotherapy-resistant and myeloma-propagating cells. CD229 Protein, Human, Recombinant (His & Avi), B... |
|
TMPK-01412
|
HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi)
SARS-CoV-2 epitope,MHC
|
Human
|
HEK293 Cells
|
|
HLA-B*15:01 is strongly associated with asymptomatic infection with SARS-CoV-2 and is likely to be involved in the mechanism underlying early viral clearance. T cells from pre-pandemic individuals carrying HLA-B*15:01 were reactive to the immunodominant SARS-CoV-2 S-derived peptide NQKLIANQF, and 100% of the reactive cells displayed memory phenotype. |
|
TMPK-01466
|
HLA-A*02:01&B2M&HPV 16 E6 (KLPQLCTEL) Tetramer Protein, Human, MHC (His & Avi)
Human papillomavirus type 16,E6,HPV16
|
Human
|
HEK293 Cells
|
|
Human papillomavirus (HPV) 16 infection is a necessary condition for the pathogenesis and development of cervical cancer. The E6 protein is expressed by the HPV16 E6 gene and promotes malignant phenotype transformation, which is an important mechanism for the occurrence and development of cervical cancer. |
|
TMPK-00357
|
CD229 Protein, Human, Recombinant (His & Avi)
LY9,T100,AI893573,SLAMF3,Lgp100,CD229
|
Human
|
HEK293 Cells
|
|
CD229 was strongly and homogeneously overexpressed on the PC of patients with monoclonal gammopathy of undetermined significance (MGUS), smoldering myeloma, MM, and PC leukemia. CD229 was particularly overexpressed on those PC showing an abnormal phenotype such as expression of CD56. Most importantly, CD229 was also highly expressed on those cells in the patients' BM displaying the phenotype of chemotherapy-resistant and myeloma-propagating cells. CD229 Protein, Human, Recombinant (His & Avi) is... |
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TMPY-02581
|
STAT4 Protein, Human, Recombinant (His)
signal transducer and activator of transcription 4,SLEB11
|
Human
|
Baculovirus Insect Cells
|
|
High expression of STAT4 in gastric cancer predicted a better clinical outcome. STAT4 might be a useful biomarker to identify patients at high risk of recurrence after gastrectomy. Genetic variants in the transcription factor STAT4 are associated with increased susceptibility to systemic lupus erythematosus (SLE) and a more severe disease phenotype. |
|
TMPK-00237
|
2B4/CD244 Protein, Human, Recombinant (aa 22-221, His & Avi), Biotinylated
NAIL,CD244,SLAMF4,h2B4,NKR2B4,Nmrk,CD244 antigen,2B4
|
Human
|
HEK293 Cells
|
|
2B4 (CD244) is expressed by memory-phenotype CD8() T cells and all natural killer (NK) cells. The ligand for 2B4, CD48, is expressed on hematopoietic cells. 2B4 is conserved in humans and mice, and a number of reports have linked 2B4 with activation of lymphocytes.Engagement of 2B4 on NK cell surfaces with specific antibodies or CD48 can trigger cell mediated cytotoxicity, interferon γ secretion, phosphoinositol turnover and NK cell invasiveness. |
|
TMPK-00922
|
DLK1 Protein, Human, Recombinant (aa 24-303, His)
FA1,Pref1,DLK1,pG2,DLK,secredeltin,ZOG,DLK-1
|
Human
|
HEK293 Cells
|
|
paternally inherited genetic defects of DLK1 were identified in four families with nonsyndromic CPP and a metabolic phenotype. DLK1 encodes a transmembrane protein that is important for adipose tissue homeostasis and neurogenesis and is located in the imprinted chromosome 14q32 region associated with Temple syndrome. DLK1 Protein, Human, Recombinant (aa 24-303, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 30.9 kDa and the accession number is P8037... |
|
TMPK-00921
|
DLK1 Protein, Human, Recombinant (hFc)
DLK1,FA1,pG2,ZOG,secredeltin,DLK,Pref1,DLK-1
|
Human
|
HEK293 Cells
|
|
paternally inherited genetic defects of DLK1 were identified in four families with nonsyndromic CPP and a metabolic phenotype. DLK1 encodes a transmembrane protein that is important for adipose tissue homeostasis and neurogenesis and is located in the imprinted chromosome 14q32 region associated with Temple syndrome. DLK1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 56.58 kDa and the accession number is P80370-1. |
|
TMPY-04420
|
TLK1 Protein, Human, Recombinant (His & GST)
KIAA0137,PKU-beta,tousled like kinase 1,PKU-β
|
Human
|
Baculovirus Insect Cells
|
|
Tousled-like kinase 1 (or protein kinase ubiquitous, PKU-beta/TLK1) is a serine/threonine protein kinase that is implicated in chromatin remodeling, DNA replication and mitosis. TLK1 has a function important for proper chromosome segregation and maintenance of diploid cells at mitosis in mammalian cells that could be mediated by reduced phosphorylation of histone H3 and condensation of chromosomes, although other explanations to the phenotype are possible. |
|
TMPJ-00939
|
CTH Protein, Human, Recombinant
γ-Cystathionase,Cystathionine γ-Lyase,Cystathionine Gamma-Ly...
|
Human
|
E. coli
|
|
Cystathionine Gamma-Lyase (CTH) belongs to the trans-sulfuration enzymes family. CTH exists as a homotetramer and interacts with CALM in a calcium-dependent manner. CTH breaks down cystathionine into cysteine, ammonia and 2-oxobutanoate. CTH catalyzes the last step in the trans-sulfuration pathway from methionine to cysteine and has broad substrate specificity. Defects in CTH will lead to cystathioninuria, which is an autosomal recessive phenotype characterized by abnormal accumulation of plasma... |
|
TMPY-03267
|
Sorcin/SRI Protein, Human, Recombinant (His & GST)
CP-22,CP22,sorcin,V19,SCN
|
Human
|
Baculovirus Insect Cells
|
|
Sorcin was originally identified in multidrug-resistant cells. It is a calcium-binding protein. Sorcin modulates excitation-contraction coupling in the heart, contributes to calcium homeostasis in the heart sarcoplasmic reticulum. Sorcin is overexpressed in the multi-drug resistant chinese hamster ovary cell line CHRC5 and a variety of multidrug-resistant tumor cell lines, but overexpression is not a sufficient or necessary condition for the acquisition of the multidrug-resistant phenotype. Sorc... |
|
TMPK-01416
|
HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi), Biotinylated
MHC,SARS-CoV-2 epitope
|
Human
|
HEK293 Cells
|
|
HLA-B*15:01 is strongly associated with asymptomatic infection with SARS-CoV-2 and is likely to be involved in the mechanism underlying early viral clearance. T cells from pre-pandemic individuals carrying HLA-B*15:01 were reactive to the immunodominant SARS-CoV-2 S-derived peptide NQKLIANQF, and 100% of the reactive cells displayed memory phenotype. |
|
TMPY-03288
|
USP30 Protein, Human, Recombinant (SUMO)
ubiquitin specific peptidase 30
|
Human
|
Baculovirus Insect Cells
|
|
Ubiquitin specific peptidase 30, also known as USP30, is a deubiquitinating enzyme that is embedded in the mitochondrial outer membrane. Depletion of USP30 expression by RNA interference induced elongated and interconnected mitochondria, depending on the activities of the mitochondrial fusion factors mitofusins, without changing the expression levels of the key regulators for mitochondrial dynamics. Mitochondria were rescued from this abnormal phenotype by ectopic expression of USP30 in a manner... |
|
TMPK-01274
|
DLK1 Protein, Cynomolgus, Recombinant (His)
FA1,DLK-1,secredeltin,DLK1,ZOG,DLK,Pref1,pG2
|
Cynomolgus
|
HEK293 Cells
|
|
paternally inherited genetic defects of DLK1 were identified in four families with nonsyndromic CPP and a metabolic phenotype. DLK1 encodes a transmembrane protein that is important for adipose tissue homeostasis and neurogenesis and is located in the imprinted chromosome 14q32 region associated with Temple syndrome. DLK1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 31.26 kDa and the accession number is A0A2K5TMQ6... |
|
TMPH-01558
|
IL12RB2 Protein, Human, Recombinant (His)
Interleukin-12 receptor subunit beta-2,IL12RB2
|
Human
|
P. pastoris (Yeast)
|
|
Receptor for interleukin-12. This subunit is the signaling component coupling to the JAK2/STAT4 pathway. Promotes the proliferation of T-cells as well as NK cells. Induces the promotion of T-cells towards the Th1 phenotype by strongly enhancing IFN-gamma production. IL12RB2 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 69.7 kDa and the accession number is Q99665. |
|
TMPY-03458
|
Sorcin/SRI Protein, Human, Recombinant
sorcin,SCN,CP22,V19,CP-22
|
Human
|
Baculovirus Insect Cells
|
|
Sorcin was originally identified in multidrug-resistant cells. It is a calcium-binding protein. Sorcin modulates excitation-contraction coupling in the heart, contributes to calcium homeostasis in the heart sarcoplasmic reticulum. Sorcin is overexpressed in the multi-drug resistant chinese hamster ovary cell line CHRC5 and a variety of multidrug-resistant tumor cell lines, but overexpression is not a sufficient or necessary condition for the acquisition of the multidrug-resistant phenotype. Sorc... |
|
TMPK-01138
|
PLD4 Protein, Human, Recombinant (His)
5'-3' exonuclease PLD4,PLD 4,Phospholipase D4,Choline phosph...
|
Human
|
HEK293 Cells
|
|
Phospholipase D4 (PLD4) is a newly identified protein expressed in microglia. the expression of PLD4 was located in macrophages in the colon cancer mesenchymal and lymph nodes as shown by immunohistochemical analysis. furthermore, its expression was associated with clinical staging of colon cancer. Then, THP-1 as a cell model induced into TAMs. PLD4 could be involved in the activation process of M1 phenotype macrophages. PLD4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cel... |
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TMPJ-00423
|
TIM-1/KIM-1/HAVCR1 Protein, Mouse, Recombinant (His)
Hepatitis A virus cellular receptor 1 homolog,HAVcr-1,T cell...
|
Mouse
|
HEK293 Cells
|
|
TIM-1/KIM-1/HAVCR belongs to the immunoglobulin superfamily that cosisits 305 amino acid (aa). It is expressed by stimulated T-cells. TIM-1/KIM-1/HAVCR may play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4. And may have a role in kidney injury and repair. Belongs to the T-cell and airway phenotype regulator (Tapr) locus, a single chromosomal region that confers reduced T-helper type 2 responsiveness and protects against airway hypera... |
|
TMPY-00999
|
UNC5A Protein, Human, Recombinant (His)
unc-5 homolog A (C. elegans),UNC5H1
|
Human
|
HEK293 Cells
|
|
The netrin-1 receptor Uncoordinated Phenotype-5A, or UNC5A, plays an important role in predicting response to DNA damage induced by chemotherapeutic drug and regulating cell death in bladder cancer. Moreover, UNC5A is cumulatively downregulated by the unfolding protein response (UPR) at the transcriptional level in vitro and at the translational level both in vitro and in vivo. Also, UNC5A is a novel transcriptional target of p53 and plays a role in p53-dependent apoptosis. UNC5A Protein, Human,... |
|
TMPK-01079
|
PLD4 Protein, Mouse, Recombinant (His)
Choline phosphatase 4,5'-3' exonuclease PLD4,Phospholipase D...
|
Mouse
|
HEK293 Cells
|
|
Phospholipase D4 (PLD4) is a newly identified protein expressed in microglia. the expression of PLD4 was located in macrophages in the colon cancer mesenchymal and lymph nodes as shown by immunohistochemical analysis. furthermore, its expression was associated with clinical staging of colon cancer. Then, THP-1 as a cell model induced into TAMs. PLD4 could be involved in the activation process of M1 phenotype macrophages. PLD4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cel... |
|
TMPY-04801
|
Fibromodulin Protein, Human, Recombinant (hFc)
FM,fibromodulin,SLRR2E
|
Human
|
HEK293 Cells
|
|
Fibromodulin (FMOD), an ECM small leucine-rich proteoglycan (SLRP), was reported to promote angiogenesis not only during wound healing, but also in optical and cutaneous angiogenesis-dependent diseases. The autocrine FMOD of cancer cells may promote tumor angiogenesis of SCLC by upregulating the expression of angiogenic factors that act in concert to facilitate the angiogenic phenotype of endothelial cells as a proangiogenic factor. Therefore, silencing FMOD may be a potentially clinical therap... |
|
TMPY-04478
|
IP6K1/IHPK1 Protein, Human, Recombinant (His & GST)
inositol hexakisphosphate kinase 1,IHPK1,PiUS
|
Human
|
Baculovirus Insect Cells
|
|
IP6K1 (Inositol Hexakisphosphate Kinase 1) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. IHPK1 is an inositol hexaphosphate kinase (IHPK) protein that belongs to the inositol phosphokinase (IPK) family. IHPK proteins are likely responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). IHPK1 may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4 and affect the growth-suppressive and... |
|
TMPY-02394
|
IMPA1 Protein, Human, Recombinant (His)
IMPA,inositol(myo)-1(or 4)-monophosphatase 1,IMP
|
Human
|
E. coli
|
|
IMPA1 (Inositol Monophosphatase 1) is a Protein Coding gene. This gene encodes an enzyme that dephosphorylates Myo-inositol monophosphate to generate free Myo-inositol, a precursor of phosphatidylinositol, and is, therefore, an important modulator of intracellular signal transduction via the production of the second messenger's myoinositol 1,4,5-trisphosphate and diacylglycerol. Despite its many physiological functions, no clinical phenotype has been assigned to this gene dysfunction to date. Ad... |
|
TMPY-00585
|
Annexin A8 Protein, Human, Recombinant (His)
ANX8,annexin A8
|
Human
|
E. coli
|
|
We have previously shown that Annexin A8 (ANXA8) is strongly associated with the basal-like subgroup of breast cancers, including BRCA1-associated breast cancers, and poor prognosis; while in the mouse mammary gland AnxA8 mRNA is expressed in low-proliferative isolated pubertal mouse mammary ductal epithelium and after enforced involution, but not in isolated highly proliferative terminal end buds (TEB) or during pregnancy. ANXA8 as a potential mediator of quiescence in the normal mouse mammary ... |
|
TMPY-00648
|
UNC5A Protein, Human, Recombinant (hFc)
UNC5H1,unc-5 homolog A (C. elegans)
|
Human
|
HEK293 Cells
|
|
The netrin-1 receptor Uncoordinated Phenotype-5A, or UNC5A, plays an important role in predicting response to DNA damage induced by chemotherapeutic drug and regulating cell death in bladder cancer. Moreover, UNC5A is cumulatively downregulated by the unfolding protein response (UPR) at the transcriptional level in vitro and at the translational level both in vitro and in vivo. Also, UNC5A is a novel transcriptional target of p53 and plays a role in p53-dependent apoptosis. UNC5A Protein, Human,... |
|
TMPK-00090
|
NKp30/NCR3 Protein, Human, Recombinant (His & Avi)
NKp30,1C7,MALS,CD337,LY117,NCR3
|
Human
|
HEK293 Cells
|
|
NKp30, along with NKp44 and NKp46, constitute a group of receptors termed "Natural Cytotoxicity Receptors". These receptors play a major role in triggering NK-mediated killing of most tumor cells lines.NKp30 stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells. Engagement of NCR3 by BAG6 also promotes myeloid dendritic cells (DC) maturation, both through killing DCs that did not acquire a mature ph... |
|
TMPJ-01005
|
Lumican Protein, Mouse, Recombinant (His)
KSPG lumican,Lumican,Keratan sulfate proteoglycan lumican
|
Mouse
|
HEK293 Cells
|
|
Keratan sulfate proteoglycan lumican, mostly known as lumican, belongs to the SLRP class II subfamily and the small leucine-rich proteoglycan (SLRP) family. Lumican binds to laminin. It has positive regulation of transcription from RNA polymerase II promoter and transforming growth factor beta1 production. Lumican is expressed in a variety of tissues, including skin, artery, lung, cornea, kidney, bone, aorta, and articular cartilage. The abnormal connective tissue phenotype seen in the Lumican n... |
|
TMPY-01346
|
Psoriasin/S100A7 Protein, Human, Recombinant
S100 calcium binding protein A7,PSOR1,S100A7c
|
Human
|
E. coli
|
|
Protein S100-A7, also known as S100 calcium-binding protein A7, Psoriasin, S100A7, and PSOR1, is a secreted protein which belongs to theS-100 family. S100A7 was first isolated from skin involved by psoriasis, which can be induced in cultured squamous epithelial cells. S100A7 is expressed by both normal cultured and malignant keratinocytes and malignant breast epithelial cells within ductal carcinoma in situ, suggesting an association with abnormal pathways of differentiation. S100A7 plays a role... |
|
TMPY-04930
|
Notch 2 Protein, Human, Recombinant (His)
AGS2,HJCYS,hN2,notch 2
|
Human
|
Baculovirus Insect Cells
|
|
NOTCH2 (Notch Receptor 2) is a Protein Coding gene. This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics and play a role in a variety of developmental processes by controlling cell fate decisions. Hajdu Cheney Syndrome (HCS) is a rare disease associated with mutations of NOTCH2 that lead to the translation of a truncated, presumably stable, NOTCH2 protein. NOTCH2 is down-regulated in colon cancer, and reduced express... |
|
TMPY-01595
|
PCBP1 Protein, Human, Recombinant (His)
HNRPE1,hnRNP-E1,HEL-S-85,HNRPX,poly(rC) binding protein 1,hn...
|
Human
|
E. coli
|
|
Poly(rC)-binding protein 1, also known as Heterogeneous nuclear ribonucleoprotein E1, Alpha-CP1, Nucleic acid-binding protein SUB2.3 and PCBP1, is a family member of heterogeneous nuclear ribonucleoproteins (hnRNPs) that belong to RNA-binding proteins and bear three KH domains. PCBP1 is loosely bound in the nucleus. It may shuttle between the nucleus and the cytoplasm. It is abundantly expressed in skeletal muscle, thymus and peripheral blood leukocytes while a lower expression is observed in pr... |
|
TMPY-04471
|
APEG1 Protein, Human, Recombinant (His)
SPEG complex locus,BPEG,SPEGalpha,SPEGβ,APEG-1,SPEGbeta,APEG...
|
Human
|
E. coli
|
|
Striated muscle preferentially expressed protein kinase, also known as aortic preferentially expressed protein 1, APEG-1, SPEG and KIAA1297, is a protein that belongs to the protein kinase superfamily and CAMK Ser/Thr protein kinase family. SPEG / APEG-1 contains two fibronectin type-III domains, nine Ig-like (immunoglobulin-like) domains, two protein kinase domains. Isoform 1 of SPEG is preferentially expressed in striated muscle. Non-kinase form such as isoform 3 of SPEG is predominantly expre... |
|
TMPY-04417
|
DAPK1 Protein, Human, Recombinant (aa 1-363, His & GST)
DAPK,death-associated protein kinase 1,ROCO3
|
Human
|
Baculovirus Insect Cells
|
|
Death-associated protein kinase 1, also known as DAP kinase 1, DAPK1 and DAPK, is a cytoplasm protein which belongs to theprotein kinase superfamily, CAMK Ser / Thr protein kinase family and DAP kinase subfamily. DAPK1 contains tenANK repeats, onedeath domain and oneprotein kinase domain. DAPK1 is a calcium / calmodulin-dependent serine/threonine kinase which acts as a positive regulator of apoptosis. DAPK1 gene is a candidate tumor suppressor (TSG) and the abnormal methylation of DAPK1 g... |
|
TMPY-02440
|
SAP/SH2D1A Protein, Human, Recombinant (His)
XLPD,EBVS,DSHP,SAP,MTCP1,IMD5,SH2 domain containing 1A,LYP,S...
|
Human
|
E. coli
|
|
SH2domain-containing protein 1A (SH2D1A / SAP) is a 128 amino acid protein, containing a single Src homology 2 (SH2) domain, flanked by 5 amino acids at the N-terminus and 25 amino acids at the C-terminus. The absence of a catalytic domain and the presence of an SH2domain suggest that SH2D1A regulates one or more signal transduction pathways. SH2D1A interacts with signaling lymphocytic activation molecule (SLAM), which is a transmembrane protein expressed on the surface of activated T and B cell... |
|
TMPY-02488
|
HOXA1 Protein, Human, Recombinant (His)
BSAS,homeobox A1,HOX1F,HOX1
|
Human
|
E. coli
|
|
Homeobox protein Hox-A1 is a transcription factor encoded by the HOXA1 gene. This gene is one of the four types of homeobox genes each of which contains a homeobox DNA sequence that codes for the homeodomain, a region of 60 amino acids responsible for the DNA binding exhibited by these homeobox proteins. These Homeobox genes are essential metazoan genes as they determine the identity of embryonic regions along the anterior-posterior axis. The homeobox protein Hox-A1 may be involved in the placem... |
|
TMPY-02497
|
S100A15 Protein, Mouse, Recombinant (His & MBP)
S100a17l1,Gm1020,S100a15a,AY465109,S100A7f,S100A7L1,S100 cal...
|
Mouse
|
E. coli
|
|
Koebnerisin is also known as protein S100-A7A (S100A7A), S100 calcium-binding protein A7-like 1 (S100A7L1) or S100 calcium-binding protein A15 (S100A15). Human S100A7A / S100A15 is a novel member of the S100 family of EF-hand calcium-binding proteins and was recently identified in psoriasis, where it is significantly upregulated in lesional skin. S100A7 is expressed by both normal cultured and malignant keratinocytes and malignant breast epithelial cells within ductal carcinoma in situ, suggesti... |
|
TMPY-01854
|
DPP10 Protein, Human, Recombinant (His)
DPPY,DPRP3,DPRP-3,DPL2,dipeptidyl-peptidase 10 (non-function...
|
Human
|
HEK293 Cells
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Inactive dipeptidyl peptidase 1, also known as Dipeptidyl peptidase IV-related protein 3, Dipeptidyl peptidase X, Dipeptidyl peptidase-like protein 2, DPRP-3, DPL2 and DPP1, is a single-pass type II membrane protein which belongs to thepeptidase S9B family.DPPIV subfamily. It may modulate cell surface expression and activity of the potassium channels KCND1 and KCND2. DPP1 / DPRP3 has no detectable protease activity, most likely due to the absence of the conserved serine residue normally p... |
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TMPY-02248
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Myocilin Protein, Human, Recombinant (His)
myocilin, trabecular meshwork inducible glucocorticoid respo...
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Human
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HEK293 Cells
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Myocilin, also known as Trabecular meshwork-induced glucocorticoid response protein, MYOC, and GLC1A, is a protein that contains one olfactomedin-like domain. Myocilin / MYOC may participate in the obstruction of fluid outflow in the trabecular meshwork. Myocilin / MYOC is expressed in large amounts in various types of muscle, ciliary body, papillary sphincter, skeletal muscle, heart, and other tissues. Myocilin / MYOC is expressed predominantly in the retina. In normal eyes, it is found in the ... |
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TMPY-02841
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Fragilis/IFITM3 Protein, Human, Recombinant (mFc)
DSPA2b,1-8U,interferon induced transmembrane protein 3,IP15
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Human
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HEK293 Cells
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Interferon-induced transmembrane protein 3 (IFITM3) belongs to the CD225 family. To replicate, viruses must gain access to the host cell's resources. Interferon (IFN) regulates the actions of a large complement of interferon effector genes (IEGs) that prevent viral replication. The interferon-inducible transmembrane protein family members, IFITM1, 2, and 3, are IEGs required for inhibition of influenza A virus, dengue virus, and West Nile virus replication in vitro. IFITM3 is an IFN-induced anti... |
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TMPJ-00359
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SLAMF3 Protein, Human, Recombinant (His)
Signaling lymphocytic activation molecule 3,CD229,Cell surfa...
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Human
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HEK293 Cells
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SLAMF3 (CD229) is a type I transmembrane glycoprotein in the SLAM subgroup of the CD2 family. Mature human SLAMF3 consists of a 407 amino acid (aa) extracellular domain (ECD) with two Ig-like V-set and two Ig-like truncated C2-set domains. The ECD of human SLAMF3 shares 57% - 59% aa sequence identity with mouse and rat SLAMF3. Within the first two Ig-like domains that are common to all SLAM proteins, human SLAMF3 shares 24% - 39% aa sequence identity with human 2B4, BLAME, CD2F-10, CD84, CRACC, ... |
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TMPJ-01259
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CD3 epsilon/CD3e Protein, Cynomolgus, Recombinant (aa 22-117, hFc)
CD3 epsilon,T-cell antigen receptor complex, epsilon subunit...
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Cynomolgus
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HEK293 Cells
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T-cell surface glycoprotein CD3 epsilon chain, also known as CD3E, is a single-pass type I membrane protein. CD3E contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3E, together with CD3-gamma, CD3-delta and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. The CD3 epsilon subunit of the T cell receptor (TCR) complex contains two defined signaling domains, a proline-rich sequence and an immune tyrosine activation m... |
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