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21
Cat. No. | Product Name | ||
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L6810 | 中药单体化合物库 | 2755 compounds | |
2755 种中药来源的单体化合物,是药物开发、药理研究等领域的有力工具; |
Cat. No. | Product Name | Form | Specificity Of Inhibition |
---|---|---|---|
C0004 |
Phosphatase Inhibitor Cocktail III (2 Tubes, 100x)
磷酸酶抑制剂 Cocktail III (2 Tubes, 100x) |
2 Tube Solution (100×) | Each Tube has different specificity of inhibition |
C0002 |
Phosphatase Inhibitor Cocktail I (100× ddH2O)
磷酸酶抑制剂 Cocktail I (100× ddH2O) |
Solution (100× in ddH2O) | Acid Phosphatase, Alkaline phosphatase, PTPs, ATPases |
C0003 |
Phosphatase Inhibitor Cocktail II (100× DMSO)
磷酸酶抑制剂 Cocktail II (100× DMSO) |
Solution (100× in DMSO) | Alkaline phosphatases, Ser/Thr phosphatases, Acid and PP1 and PP2A |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T3658 |
Trifluridine/tipiracil hydrochloride mixture
Trifluridine-tipiracil hydrochloride mixture,TAS102,TAS-102,TAS 102 |
Nucleoside Antimetabolite/Analog; DNA/RNA Synthesis | Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
Trifluridine/tipiracil hydrochloride mixture (TAS-102) 是一种新型口服组合药物,含有摩尔比为 2:1 的曲氟尿苷(TFT) 和盐酸替吡嘧啶 (TTP)。它主要通过抑制胸苷酸合酶 (TS) 和掺入 DNA 来显示抗肿瘤活性。 | |||
T10760 |
Ceramides Mixture
神经酰胺混合物,神经酰胺 |
Telomerase | DNA Damage/DNA Repair |
Ceramides Mixture 是表皮渗透屏障的主要脂质成分,参与生长抑制,细胞周期停滞和端粒酶活性的调节。它是一种内源性神经酰胺,由含羟基和非羟基脂肪酸的神经酰胺组成。 | |||
T11216 |
Eplivanserin (mixture)
Eplivanserin mixture,SR-46349 (mixture) |
5-HT Receptor | GPCR/G Protein; Neuroscience |
Eplivanserin mixture is a selective serotonin reuptake inhibitor and a 5-HT2A receptor antagonist, | |||
T38027 |
Ganglioside GM2 Asialo Mixture
Ganglioside GM2 Asialo Mixture |
Others | Others |
Ganglioside GM2 asialo (asialo- GM2) is a glycosphingolipid containing three monosaccharide residues and a fatty acid of variable chain length but lacking the sialic acid residue present on ganglioside M2. Asialo-GM2 levels are low-to-undetectable in normal human brain, but it accumulates in the brain of patients with Tay-Sachs and Sandhoff disease, which are neurodegenerative disorders characterized by deficiency of lysosomal β-hexosaminidase A and B, respectively. It also binds to various bact... | |||
T36862 |
Ganglioside GT1b Mixture (sodium salt)
Ganglioside GT1b Mixture (sodium salt),Ganglioside G1 Mixture |
Others | Others |
Ganglioside GT1b is a trisialoganglioside that is characterized by having two sialic residues linked to the inner galactose unit. It binds to the neurotoxins botulinum toxin serotype A (BTxA), BTxA heavy chain, and tetanus toxin with IC50 values of 11, 0.74, and 7.2 μM, respectively.[1] Ganglioside GT1b-containing liposomes bind to the major coat protein VP1 from Merkel cell polyomavirus (MCPyV), which has been identified in Merkel cell carcinomas, identifying ganglioside GT1b as a putative MCP... | |||
T36861 |
Ganglioside GD1b Mixture (sodium salt)
Ganglioside GD1b Mixture (sodium salt) |
Others | Others |
Ganglioside GD1b is an acidic glycosphingolipid that contains two sialic acid residues linked to an inner galactose unit. It is a component of plasma membranes where it packs densely with cholesterol to form lipid microdomains that modulate both intra- and intercellular signaling events. The concentration of ganglioside GD1b in human brain increases with age, constituting 7.85% of total sialic acid in the brain of 0- to 10-year-old subjects and 20.29% in 11- to 30-year-old subjects. Ganglioside ... | |||
T36413 |
N-glycolyl-Ganglioside GM3 Mixture (ammonium salt)
N-glycolyl-Ganglioside GM3 Mixture (ammonium salt) |
Others | Others |
N-glycolyl-Ganglioside GM3(NeuGc-GM3) is a form of ganglioside GM3 that contains an N-glycolylated sialic acid (NeuGc). | |||
T35983 |
Carotenoid Mixture
|
Others | Others |
Carotenoid mixture is a mixture of carotenoids that contains the antioxidative and anti-inflammatory carotenoid capsanthin and the antioxidative vitamin A precursor β-carotene , as well as additional carotenoids and carotenoid esters.1,2,3,4 1.Kim, J.S., Lee, W.M., Rhee, H.C., et al.Red paprika (Capsicum annuum L.) and its main carotenoids, capsanthin and β-carotene, prevent hydrogen peroxide-induced inhibition of gap-junction intercellular communicationChem. Biol. Interact.254146-155(2016) 2.Na... | |||
T37963 |
Methylchloroisothiazolinone/Methylisothiazolinone Mixture
|
Others | Others |
Methylchloroisothiazolinone/methylisothiazolinone mixture (MCIT/MIT) is a mixture of isothiazolinone-derived biocides.1,2It is effective against Gram-positive and Gram-negative bacteria with MIC values of 0.0002, 0.0002, 0.00005, and 0.00005% (w/w) forS. aureus,P. aeruginosa,A. niger, andC. albicans, respectively.2MCIT/MIT can elicit contact sensitization.3Formulations containing MCIT/MIT have been used for controlling microbial growth in industrial and household products. 1.Frenzel, E., Schmidt... | |||
T38081 |
Tunicamycin 14:1 Mixture
|
Others | Others |
Tunicamycin 14:1 is a mixture of tunicamycin structural isomers that contain a 14-carbon N-acyl chain with variable branching patterns. The N-acyl chain incorporated into tunicamycins, like tunicamycin 14:1, is derived from the same pool of cellular branched-chain fatty acids (BCFAs) in Streptomyces and directly impacts the biological activity of each individual tunicamycin variant.1,2,3Purified tunicamycin 14:1 with the iso branching configuration inhibits bacterial phospho-MurNAc-pentapeptide ... | |||
T38083 |
Tunicamycin 17:1 Mixture
|
Others | Others |
Tunicamycin 17:1 is a mixture of tunicamycin structural isomers that contain a 17-carbon N-acyl chain with variable branching patterns. The N-acyl chain incorporated into tunicamycins, like tunicamycin 17:1, is derived from the same pool of cellular branched-chain fatty acids (BCFAs) inStreptomycesand directly impacts the biological activity of each individual tunicamycin variant.1,2,3Purified tunicamycin 17:1 withisooranteisobranching configurations inhibits bacterial phospho-MurNAc-pentapeptid... | |||
T37295 |
Ganglioside GM1 Asialo Mixture
|
Others | Others |
Ganglioside GM1 asialo is a component of cellular lipid rafts and can be formed by the cleavage of the sialic acid residue from ganglioside GM1 by neuraminidase. Ganglioside GM1 asialo is a glycolipid receptor for P. aeruginosa flagellin and stimulates defensive responses in host cells, including extracellular ATP release, calcium mobilization, and ERK1/2 phosphorylation when stimulated by flagellin and an anti-ganglioside GM1 asialo antibody. The percentage of ganglioside GM1 asialo-positive na... | |||
T38082 |
Tunicamycin 15:1 Mixture
|
Others | Others |
Tunicamycin 15:1 is a mixture of tunicamycin structural isomers that contain a 15-carbon N-acyl chain with variable branching patterns. The N-acyl chain incorporated into tunicamycins, like tunicamycin 15:1, is derived from the same pool of cellular branched-chain fatty acids (BCFAs) inStreptomycesand directly impacts the biological activity of each individual tunicamycin variant.1,2,3Purified tunicamycin 15:1 withiso,anteiso, or a mixture ofisoandanteisobranching configurations inhibit bacteria... | |||
T35588 |
Ganglioside GM3 Mixture (sodium salt)
|
Others | Others |
Ganglioside GM3 is a monosialoganglioside that demonstrates antiproliferative and proapoptotic effects in tumor cells by modulating cell adhesion, proliferation, and differentiation. It suppresses angiogenesis and reduces proliferation and migration of human umbilical vein endothelial cells (HUVECs) when used at a concentration of 20 μM via inhibition of VEGFR2 and Akt phosphorylation. Ganglioside GM3 induces dissociation of the insulin receptor-caveolin-1 complex from lipid microdomains, functi... | |||
T35930 |
Ganglioside GM2 Mixture (sodium salt)
|
Others | Others |
Ganglioside GM2 is a glycosphingolipid component of cellular membranes, primarily the plasma membrane. Levels of ganglioside GM2 are elevated in the brain of patients with Sandhoff disease, as well as feline and mouse models of the disease. Ganglioside GM2 accumulates in the lysosomes of individuals with Tay-Sachs disease and GM2-activator deficiency, as well as in the CNS of patients with and animal models of mucopolysaccharide storage disorders and Niemann-Pick disease types A, C1, and C2. Gan... | |||
T35552 |
Ganglioside GD3 Mixture (sodium salt)
|
Others | Others |
Ganglioside GD3 is synthesized by the addition of two sialic acid residues to lactosylceramide and can serve as a precursor to the formation of more complex gangliosides by the action of glycosyl- and sialyltransferases. It induces apoptosis in HuT-78 cutaneous T cell lymphoma cells in a concentration-dependent manner and disrupts the mitochondrial membrane potential when used at a concentration of 200 μM. Expression of ganglioside GD3 in GD3-negative SK-MEL-28-N1 malignant melanoma cells increa... | |||
T39206 |
HKSOX-1m (5/6-mixture)
|
||
HKSOX-1m (5/6-mixture) serves as a mitochondria-targeting O2 fluorescent probe with an excitation/emission wavelength of 509/534nm (green), showcasing exceptional selectivity and sensitivity for O2 across a wide pH spectrum and in the presence of strong oxidants and prevalent reductants within cells. | |||
T30739 |
Carbendazim mixture with flusilazole
|
Others | Others |
Carbendazim mixture with flusilazole is a bioactive chemical. | |||
T35553 |
Ganglioside GQ1b Mixture (sodium salt)
|
Others | Others |
Ganglioside GQ1b is a tetrasialoganglioside that contains two sialic acid residues linked to an inner galactose unit. It stimulates phosphorylation of several ecto-type protein kinase substrates on the surface of GOTO human neuroblastoma cells when used at a concentration of 5 nM. Ganglioside GQ1b promotes differentiation of murine embryonic stem cells (mESCs) to neuronal precursor and glial cells via activation of the ERK1/2 pathway. It also induces differentiation of murine keratinocytes throu... | |||
T30985 |
Clorpropham mixture with propham
|
Others | Others |
Clorpropham mixture with propham is a bioactive chemical. | |||
T37582 |
Ganglioside GM1 Mixture (ovine) (ammonium salt)
|
Others | Others |
Ganglioside GM1is a monosialylated ganglioside and the prototypic ganglioside for those containing one sialic acid residue.1,2It is found in a large variety of cells, including immune cells and neurons, and is enriched in lipid rafts in the cell membrane.3It associates with growth factor receptors, including TrkA, TrkB, and the GDNF receptor complex containing Ret and GFRα, and is required for TrkA expression on the cell surface. Ganglioside GM1interacts with other proteins to increase calcium i... | |||
T31715 |
Ethynylestradiol mixture with lynestrenol
|
Others | Others |
Ethynylestradiol mixture with lynestrenol is a drug/ therapeutic agent with reproductive effect. | |||
T35587 |
Ganglioside GD1a mixture (sodium salt)
Ganglioside B1 |
Others | Others |
Ganglioside GD1a is a sialic acid-containing glycosphingolipid found in brain, erythrocytes, bone marrow, testis, spleen, and liver. [1] It can be shed from the surface of tumor cells into the microenvironment where it influences tumor-host cell interactions to promote tumor cell proliferation, invasion, and metastasis. Ganglioside GD1a (20 μM) also increases endothelial cell proliferation. Furthermore, ganglioside GD1a has been shown to act as a functional coreceptor for toll-like receptor 2 (T... | |||
T38933 |
HKYellow-AM (6/12-mixture)
|
||
HKYellow-AM (6/12-mixture) is a fluorogenic probe, which can be used for sensitive and specific detection of peroxynitrite. | |||
T33032 |
Lynestrenol mixture with mestranol
|
Others | Others |
Lynestrenol mixture with mestranol is a bioactive chemical. | |||
T31699 |
Ethinylestradiol mixture with Levonorgestrel
|
Others | Others |
Ethinylestradiol mixture with Levonorgestrel is formulated with increasing dosages of levonorgestrel and ethinyl estradiol. | |||
T2318 |
Sacubitril/Valsartan
Sacubitril mixture with Valsartan,沙库必曲/缬沙坦,Valsartan,Sacubitril,LCZ696 |
Apoptosis; RAAS; Neprilysin | Apoptosis; Endocrinology/Hormones; Metabolism |
Sacubitril/Valsartan (LCZ696),以1:1摩尔比由Valsartan(一种ARB)和Sacubitril(AHU377)组成,为创新口服血管紧张素受体-脑啡肽酶(ARN)双重抑制剂,旨在治疗高血压与心力衰竭。其作用机制包括抑制炎症、氧化应激及细胞凋亡,有助于改善糖尿病心肌病。 | |||
T25182 |
Budesonide mixture with salmeterol
Labazenit,Budesonide / salmeterol |
Others | Others |
Budesonide mixture with salmeterol is used as a β2 -agonist. | |||
T32758 |
Linagliptin mixture with metformin
Jentadueto Xr,Linagliptin / metformin,Jentadueto |
Others | Others |
Linagliptin mixture with metformin is used for the treatment of type 2 diabetes. | |||
T30788 |
Cefoperasone mixture with sulbactam
Bacamp,Sulperazone,Cefactam,Jincetam |
Others | Others |
Cefoperasone mixture with sulbactam is a bioactive chemical. | |||
T31578 |
Drospirenone mixture with Ethinylestradiol
Yaz 28,Nikki,Ocella,Yaz-28,Yasmin 28,Syeda |
Others | Others |
Drospirenone mixture with Ethinylestradiol is a female oral combined contraceptive containing 30 mcg (0.030 mg) Ethinyl Estradiol and 3 mg drospirenone (Androstenes). | |||
T29628 |
Acyclovir mixture with hydrocortisone
Xerese,ME 609,ME609,ME-609,Lipsovir |
Others | Others |
Acyclovir mixture with hydrocortisone is used for Herpes simplex labialis. | |||
T64399 |
Dihydroartemisinin (mixture of α and β isomers)
|
Others | Others |
Dihydroartemisinin (mixture of α and β isomers) 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T64399,CAS号为 131175-87-6。 | |||
T131583 |
Thalibrunine and Isothalibrunine, mixture of
|
Others | Others |
Thalibrunine and Isothalibrunine, mixture of 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T131583。 | |||
T73950 |
Flutax-2 (5/6-mixture)
|
||
Flutax-2 (5/6-mixture)为紫杉醇的一种活性荧光衍生物,能与α,β微管蛋白二聚体发生结合。其激发/发射波长分别为496/524 nm。紫杉醇作为红豆杉属植物产生的二萜类次生代谢物,在多种癌症研究中有应用。Flutax-2的储存应避光处理。 | |||
T73937 |
HKSOX-1r (5/6-mixture)
|
||
HKSOX-1r (5/6-mixture) 为用于成像及检测活细胞和体内内源性超氧化物的荧光探针,对超氧阴离子自由基展现出极佳的选择性与敏感性。储存方式:避光。 | |||
T73936 |
HKSOX-1 (5/6-mixture)
|
||
HKSOX-1 是一种荧光探针,用于成像和检测活细胞以及体内的内源性超氧化物。 HKSOX-1 对超氧阴离子自由基具有极好的选择性和敏感性。储存方式:避光。 | |||
T20028 |
Janumet
Efficib,Janumet XR,Metformin / sitagliptin,Metformin hydrochloride mixture with sitagliptin phosphate |
Others | Others |
Metformin hydrochloride mixture with sitagliptin phosphate is an AMP-activated protein kinase stimulant. It is also a CD26 antigen inhibitor, Gluconeogenesis inhibitor, and Glucose modulator. | |||
T30172 |
Aspartame acesulfame
乙酰舒泛-阿司帕坦盐,Aspartame acesulfame salt,Acesulfame mixture with aspartame |
Others | Others |
Aspartame acesulfame, as an artificial sweetener, is 350 times sweeter than sucrose. | |||
T73955 |
Potassium clavulanate mixture with silicon dioxide (1:1)
|
Others | Others |
Potassium clavulanate mixture with silicon dioxide (1:1)为Potassium clavulanate与Silicon dioxide按1:1比例混合而成的化合物。 | |||
T75345 |
HKSOX-1m (5/6-mixture) (hydrobromide)
|
||
HKSOX-1m (5/6-mixture) hydrobromide 是靶向线粒体的 O2•−荧光探针(Ex/Em=509/534 nm; 绿色),具有极好的选择性,且在较大范围的 pH 值区间,细胞中即使有大量强氧化剂和还原剂的时候依然有效。 | |||
T66282 |
5-Norbornene-2-methylamine (mixture of isomers)
|
Others | Others |
5-Norbornene-2-methylamine (mixture of isomers) 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T66282,CAS号为 95-10-3。 | |||
T73956 |
Amoxicillin trihydrate mixture with potassium clavulanate (4:1)
|
Others | Others |
Amoxicillin (trihydrate) mixture with potassium clavulanate (4:1) 是一种抗生素 (antibiotic),具有优良的口服吸收性及广谱抗菌作用。该化合物通过抑制细胞壁内多肽的生物合成来阻止细胞生长。 | |||
T64926 |
1-(3,5-Dimethylpyrazin-2-yl)ethanone mixture of isomers
|
Others | Others |
1-(3,5-Dimethylpyrazin-2-yl)ethanone mixture of isomers 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T64926,CAS号为 54300-08-2。 | |||
T66188 |
5-Norbornen-2-ol, mixture of endo and exo
|
Others | Others |
5-Norbornen-2-ol, mixture of endo and exo 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T66188,CAS号为 13080-90-5。 | |||
T15771 |
Lobaplatin
D-19466,络铂 |
DNA Alkylation | DNA Damage/DNA Repair |
Lobaplatin (D-19466) 是一种铂 (II) 复合物的非对映混合物,是一种有前途的抗肿瘤化疗药物,在多种肿瘤类型的患者中具有活性。 | |||
T68129L |
(+)-Picumeterol
|
Others | Others |
(+)-Picumeterol 是一种 Picumeterol 所有构型的混合体。 | |||
T23262 |
(RS)-4-Carboxyphenylglycine
|
Others | Others |
(RS)-4-Carboxyphenylglycine 是一种外消旋混合物。(S)-4-Carboxyphenylglycine 是一种选择性mGlu1α受体拮抗剂。 | |||
T8634 |
8-Bromotheophylline
Bromotheophylline,8-溴茶碱 |
Others | Others |
8-Bromotheophylline (Bromotheophylline) 是 Pamabrom 的活性部分,用于 Oxazolo[2,3-f]purinediones 的合成。Oxazolo[2,3-f]purinediones 可用于腺苷 A1和 A2A 受体上的亲和力评估。 | |||
T0517 |
Pancreatin
Pancreatic enzymes,pancrelipase,胰酶 |
Others | Others |
Pancreatin (pancrelipase) 是一种含有胰腺消化酶的猪胰腺提取物。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T4786 |
D-Ribose(mixture of isomers)
D-Ribose,D-(-)-Ribose,D-(-)-核糖 |
Others; Endogenous Metabolite | Metabolism; Others |
D-Ribose(mixture of isomers) (D-(-)-Ribose) 是 ATP 的糖部分,可作为能量增强剂,被广泛用作慢性疲劳综合症和心肌能量代谢的代谢疗法补充剂。它在蛋白质糖化中具有特性,能够 RAGE 依赖的方式诱导 NF-Κb 炎症。 | |||
T5680 |
Aloin(mixture of A&B)
芦荟素,葡糖基蒽酮,芦荟大黄素甙,芦荟苷 |
MMP; IL Receptor; Antibacterial; Antifungal | Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome |
Aloin (mixture of A&B) 是一种从芦荟中分离出来的蒽醌衍生物。它是刺激性粒细胞基质金属蛋白酶的有效抑制剂。它具有多种生物活性,如抗炎、抗菌、抗真菌、抗氧化、抗肿瘤、抗糖尿病和免疫活性。 | |||
TN3604 |
Carveol
(-)-Carveol, mixture of isomers,香芹醇 |
Endogenous Metabolite | Metabolism |
Carveol ((-)-Carveol, mixture of isomers) 是内源性代谢产物的一种。 | |||
T2742 |
Aloin
Barbaloin,芦荟素,Barbalin,Aloin-A,Aloin(mixture of A&B),Barbaloin-A,芦荟甙 |
Tyrosinase | Proteases/Proteasome |
Aloin (Aloin-A) 是天然的抗肿瘤蒽醌苷,具有铁螯合特性。 | |||
T8028 |
Farnesyl acetate
Farnesyl Acetate (mixture of isomers),3,7,11-三甲基-2,6,10-十二烷三烯-1-醇乙酸酯,乙酸法呢醇酯 |
Others | Others |
Farnesyl acetate (Farnesyl Acetate(mixture of isomers)) 是一种倍半萜,分离自 Amomum gagnepainii 中。它对红棕榈象虫幼虫有显著的毒性(LD50:7867 ppm)。 | |||
TN7559 |
Milbemectin
Milbemycin A3 (~30%) and Milbemycin A4 (~70%) Mixture |
Others | Others |
Milbemectin is composed of 30% milbemycin A3 and 70% milbemycin A4, exhibiting acaricidal and nematocidal properties effective against adult spider mites, their eggs, and C. elegans, with IC50 values of 5.3, 41.1, and 9.5 µg/ml, respectively. It functions as an allosteric agonist of the Drosophila RDL GABA receptor, and demonstrates efficacy against the pinewood nematode, B. xylophilus, with an LC20 of 0.0781 mg/liter. | |||
TN7290 |
(±)-Silybin
Silibinin (mixture of Silybin A and Silybin B) |
Others | Others |
(±)-Silybin为Silybin的消旋体,具备诱导细胞凋亡(apoptosis)、保肝、抗氧化、抗炎及抗癌等多重生物活性。 | |||
T73954 |
Leucinostatin (mixture of A&B)
|
Others | Others |
Leucinostatin (mixture of A&B) 是来自Paecilomyces lilacinus 的九肽类复合物,具有抗生素活性。 | |||
T2P2870 |
Damascenone
trans-damascenone,Beta-Damascenone,大马烯酮,大马酮 |
Others; NF-κB; Endogenous Metabolite | Metabolism; NF-κB; Others |
Damascenone 是一种 E-和 Z-异构体大马士革酮的混合物,源于Epipremnum pinnatum的具有抗炎特性的特性化合物。 | |||
T2S1797 |
Santalol
檀香醇;白檀油萜醇;檀香脑,檀香醇 |
Antioxidant; Antifungal | Microbiology/Virology; oxidation-reduction |
Santalol 是一种檀香醇的 α 和 β-异构体混合物。 其中α-santalol 分离自檀香油中,是一种有前途的抗癌药,能够预防口腔癌、前列腺癌、乳腺癌和皮肤癌。 | |||
TN2107 |
Protoescigenin
|
Others | Others |
Protoescigenin 来自七叶树皂甙混合物,可用作用于选择性保护的探索性化学的底物。 | |||
T4937 |
DL-5-Hydroxylysine hydrochloride
5-hydroxylysine hydrochloride,5-羟基-DL-赖氨酸盐酸盐 |
Others; Endogenous Metabolite | Metabolism; Others |
DL-5-Hydroxylysine hydrochloride (5-hydroxylysine hydrochloride) 是内源性代谢产物的一种。 | |||
T13827 |
Pronase E (Activity ≥ 7000 U/g)
Pronase,Pronase E |
Others | Others |
Pronase E 是一种蛋白水解酶混合物,从灰色链霉菌 (Streptomyces griseus) 中获得,能够将蛋白质消化成单个氨基酸。 | |||
T1226 |
Bacitracin
Albac,Ziba-RX,杆菌肽 |
Antibacterial; Antibiotic | Microbiology/Virology |
Bacitracin (Ziba-RX) 是一种用于葡萄球菌感染的多肽抗生素。它通过与焦磷酸十一癸烯基结合,起抑制细胞壁生物合成作用。 | |||
T1660 |
Silibinin
水飞蓟宾 A,水飞蓟宾,Silibinin A,Silybin,Silymarin I |
Reactive Oxygen Species; Autophagy | Autophagy; Immunology/Inflammation; Metabolism; NF-κB |
Silibinin (Silybin) 是水飞蓟的主要活性成分,具有抗癌和化疗预防作用,能抑制细胞增殖和迁移。 | |||
T13229 |
Tunicamycin
|
Influenza Virus; Antibacterial; Antibiotic; Antifungal | Microbiology/Virology |
Tunicamycin 是一种抗生素的混合物,通过阻断 GlcNAc 磷酸转移酶 (GPT),抑制 N-连接糖基化。Tunicamycin 具有抗肿瘤活性,还具有抗细菌、抗真菌和抗病毒活性。 | |||
T11287 |
Filipin complex
|
Antifungal | Microbiology/Virology |
Filipin complex 是一种 28 元环戊烯大环内酯类抗真菌抗生素,由 S. filipinensis、S. avermitilis 和 S. miharaensis 产生的混合物,抑制 PRRSV 病毒进入细胞,通过与膜固醇相互作用发挥作用。 | |||
T7964 |
Isomalt
异麦芽酮糖醇,Palatinitol,Palatinit |
Others; Dehydrogenase | Metabolism; Others |
Isomalt (Palatinitol) 是无毒的、具有良好耐受性的多元醇和蛋白质稳定的赋形剂,在冷冻干燥过程中可适度稳定乳酸脱氢酶(LDH),并在储存期间表现更好。它传统上在食品工业中用作甜味剂,也在制药中用作压片赋形剂。 | |||
T6752 |
S-Adenosyl-L-methionine disulfate tosylate
S-腺苷蛋氨酸对甲苯磺酸硫酸盐,Ademetionine disulfate tosylate |
DNA/RNA Synthesis | Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
S-Adenosyl-L-methionine disulfate tosylate (Ademetionine disulfate tosylate) 是一种主要生物甲基供体,在所有哺乳动物细胞中合成,但在肝脏中含量较高。 | |||
T6654 |
Saponins
Sapogenins Glycosides,皂素,Saponin |
Others | Others |
Saponins (Sapogenins Glycosides) 是一种苷类的化合物,多发现于多种植物中,可保护植物免受微生物和真菌的破坏。 | |||
T0771 |
Casanthranol
美鼠李皮蒽酚苷,鼠李蒽酚 |
Others | Others |
Casanthranol是从Rhamnus p.的干燥树皮(通常称为cascara sagrada)提取的高浓度的蒽酚苷混合物。Casanthranol 主要用于缓解便秘。Casanthranol通过其对肠壁的作用,促进肌肉收缩的增加,从而帮助肠道运动。 | |||
S00015 |
Tea polyphenol
|
Apoptosis; Others; Autophagy | Apoptosis; Autophagy; Others |
Tea polyphenol 也称为绿茶提取物,是茶中天然存在的酚类化合物,具有抗癌、抗氧化、抑制细胞增殖、诱导细胞凋亡、延缓细胞周期和调节致癌物代谢等生物活性。 | |||
T8846 |
beta-Escin
B-escin,AESCINE,beta-七叶素 |
Immunology/Inflammation related | Immunology/Inflammation |
beta-Escin 是七叶树种子的主要活性成分。它可抑制碱性成纤维细胞生长因子所诱导的增殖、迁移、管形成以及体内 CAM 血管生成。它具有研究抗血管生成作用的分子机制的潜力。 | |||
T1100 |
Polymyxin B Sulfate
Aerosporin,硫酸多粘菌素 B,PMB,Polymyxin B sulphate,硫酸多粘菌素B,Polymyxin B sulfate (1404-26-8 free base),Poly-RX |
Antibacterial; Antibiotic | Microbiology/Virology |
Polymyxin B Sulfate (Poly-RX) 是一个阳离子型表面活性剂抗生素剂,能够提高细胞膜的渗透性。 | |||
T2979 |
DL-Menthol
DL-薄荷醇,Hexahydrothymol,(±)-Menthol,薄荷醇 |
GABA Receptor; AChE | Membrane transporter/Ion channel; Neuroscience |
DL-Menthol ((±)-Menthol) 是单萜醇 (–)-薄荷醇和 (+)-薄荷醇的外消旋混合物,已在大麻中发现。它与 GABAA 受体的激活有关。 | |||
T9076 |
Spinosad
|
Others | Others |
Spinosad 是在土壤细菌 S. spinosa 中发现的一种杀虫剂,是大环内酯多杀菌素 A 和多杀菌素 D 的混合物,可作为昆虫烟碱乙酰胆碱酯酶受体 (nAChRs) 的激动剂。它具有优良的环境和哺乳动物毒理学特征,以及杀灭幼虫的活性。 | |||
T3606 |
γ-Oryzanol
谷维素,Gamma-Oryzanol,Oliver,γ-谷维素,Gammariza |
DNA Methyltransferase | Chromatin/Epigenetic |
γ-Oryzanol (Gamma-Oryzanol) 是一种从米糠油中分离出来的营养提取物,是含有甾醇和阿魏酸的混合物,有助于破坏皮肤中的自由基。它有效抑制小鼠纹状体中的 DNA 甲基转移酶(DNMTs)。 它抑制DNMT1和DNMT3a,IC50分别为 3.2 和 22.3 μM。 | |||
T38141 |
Glycerophospholipids, cephalins
Phosphatidylethanolamines (egg) |
||
Glycerophospholipids, cephalins (Phosphatidylethanolamines (egg)) 是一种从鸡蛋中分离出来的磷脂酰乙醇胺的混合物,在 sn-1和 sn-2位置有各种脂肪酰基。Glycerophospholipids, cephalins 完全水解可得到1mol 的甘油、磷酸、乙醇胺和2mol 的脂肪酸。Phosphatidylethanolamines 在膜融合和细胞分裂过程中收缩环的拆卸中起作用,可调节膜的弯曲度。Phosphatidylethanolamines 能够在没有任何蛋白质或核酸的帮助下传播传染性朊病毒。Phosphatidylethanolamines 在细菌膜中的主要作用之一是分散由阴离子膜磷脂引起的负电荷。 | |||
T38299 |
Tunicamycin V
|
Others | Others |
Tunicamycin 15:1 is a mixture of tunicamycin structural isomers that contains a 15-carbon N-acyl chain with variable branching patterns.References Tunicamycin 15:1 is a mixture of tunicamycin structural isomers that contains a 15-carbon N-acyl chain with variable branching patterns. References | |||
T19541 |
(±)20-HDHA
(±)20-HDoHE |
Others | Others |
(±)20-HDHA is an autoxidation product and is a racemic mixture of Docosahexaenoic acid (DHA). | |||
T13464L |
(-)-Ketoconazole
(-)-R 41400,(-)-Ketoconazol |
Others | Others |
(-)-Ketoconazole is one of the enantiomer of Ketoconazole. Ketoconazole is a racemic mixture of two enantiomers. | |||
TN7289 |
Cedarwood terpenes
|
Others | Others |
Cedarwood terpenes是源自雪松木的天然萜烯混合物。 | |||
TN3561 |
Cabraleone
|
Others | Others |
The mixture of cabraleone and ocotillone shows cytotoxicity against HL-60 leukaemia cell line. | |||
TN2072 |
Picroside IV
|
Others | Others |
Kutkoside is a mixture of iridoid glycosides namely, picroside II, Picroside IV and 6-ferulloylcatalpol, it may have antinociceptive and anti-inflammatory effects. | |||
TN7414 |
10-Deacetylcephalomannine
|
Others | Others |
10-Deacetylcephalomannin exhibits activity against PS leukemia in vivo; however, its instability leads to an equilibrium mixture with its cytotoxic C-7 epimer. Additionally, 10-Deacetylcephalomannine demonstrates growth inhibitory effects on human cancer cell lines, including cervical HeLa adenocarcinoma. | |||
T17185 |
Tyrothricin
|
Others | Others |
Tyrothricin is a polypeptide antibiotic mixture isolated from Bacillus brevis and consists of tyrocidines and gramicidins. Tyrothricin displays activity against bacteria, fungi, and some viruses. | |||
TN4692 |
Octadecyl p-coumarate
|
Antifection | Microbiology/Virology |
A mixture of (E)-octadecyl p-coumarate and (Z)-octadecyl p-coumarate has antifungal activity , it shows the dose dependent inhibition of the spore germination of Alternaria alternata and A. porri. | |||
T40383 |
Monensin B
|
Others | Others |
Monensin B is a polyketide compound derived from the bacterium Streptomyces cinnamonensis. Its production involves the fermentation of Streptomyces cinnamonensis, resulting in a mixture of Monensin A and Monensin B. The ratio of these two compounds depends on the concentrations of ethylmalonyl-CoA and methylmalonyl-CoA. | |||
TN7509 |
(±)-cis-Δ9-THC
(±)-3,4-cis-Δ1-Tetrahydrocannabinol |
Others | Others |
(±)-cis-Δ9-THC, a racemic mixture of the phytocannabinoid (–)-cis-Δ9-THC and synthetic cannabinoid (+)-cis-Δ9-THC, serves as an analytical reference standard. It is classified as a Schedule I compound in the United States, denoting regulation due to its notable potential for abuse. This compound is specifically designed for use in research and forensic applications. | |||
T36990 |
Moenomycin Complex
|
Others | Others |
Moenomycin complex is a mixture of moenomycins A, A12, C1, C3 and C4, which are antibiotics isolated from several strains of Streptomyces that directly inhibit bacterial peptidoglycan glycosyltransferases. [1] The minimal inhibitory concentration of moenomycin A against various Gram-positive bacteria ranges from 1-100 nM.[1] | |||
TN3686 |
Coccinic acid
|
Others | Others |
Coccinic acid shows inhibitory effects against colorectal carcinoma HCT-15 and oral epithelial cell line KB-3-1.Mixture of coccinic acid and anwuweizonic acid shows significant inhibitory activity against human decidual cells and rat luteal cells in vitro | |||
TN3426 |
Anwuweizonic acid
|
Others | Others |
Anwuweizonic acid may have inhibitory effects on 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation in mice. Mixture of coccinic acid and anwuweizonic acid has antifertility activity, shows significant inhibitory activity against human decidu | |||
T37972 |
12-OxoETE
|
Others | Others |
12-OxoETE is synthesized by human platelets and Aplysia nervous tissue after incubation with arachidonic acid. Microsomal fractions of various tissues will reduce 12-oxoETE to 12(S)-HETE or a mixture of 12(S)- and 12(R)-HETE. 12-OxoETE induces a rapid, dose dependent increase of cytoplasmic free calcium via a leukotriene B4 receptor or a common activation sequence. | |||
T38338 |
Quinolactacin A
|
Others | Others |
Quinolactactin A is a quinolone fungal metabolite originally isolated from Penicillium. It inhibits TNF production induced by LPS in murine peritoneal macrophages (IC50 = 12.2 μg/ml). It is not active against a variety of bacteria, fungi, and yeasts. Quinolactacin A is a mixture of quinolactacin A1 and A2. | |||
TN7515 |
(±)-Cannabidiol
(±)-CBD |
Others | Others |
(±)-Cannabidiol is an analytical reference standard, comprising a racemic mixture of the phytocannabinoid (−)-cannabidiol, a non-psychoactive component of cannabis, and its synthetic isomer, (+)-cannabidiol. This product is designed for use in research and forensic applications, leveraging both the naturally occurring and synthetically produced variants of cannabidiol. | |||
T11202 |
Enniatin complex
|
Others | Others |
Enniatin complex, a mixture of cyclohexadepsipeptides predominantly derived from various Fusarium species of fungi, exhibits inhibitory effects on enzymes such as acyl-CoA: cholesterol acyl transferase. Furthermore, it has demonstrated the ability to induce apoptosis in multiple cancer cell lines. In addition to these activities, the Enniatin complex possesses ionophoric, antibiotic, and in vitro hypolipidemic properties. | |||
TN3571 |
Calyxin B
|
Others | Others |
Calyxin B exhibits potent activity against human HT-1080 fibrosarcoma cells with an ED50 value of 0.69 microM. A methylated product of calyxin A and an epimeric mixture of Calyxin B, showed greatly reduced activity suggesting that phenolic hydroxyl groups | |||
TN4185 |
Hautriwaic acid
|
||
Hautriwaic acid shows anti-inflammatory activity in 12-O-tetradecanoylphorbol 13-acetate (TPA) mice ear edema models, it diminishes the joint edema induced by this mixture of polysaccharides (carrageenan), possibly by acting as immunomodulator of the infl | |||
TN5201 | Uncarinic acid E | BCL; MEK; Caspase; PI3K; Antifection; p53 | Apoptosis; MAPK; Microbiology/Virology; PI3K/Akt/mTOR signaling; Proteases/Proteasome |
Uncarinic acid E has anti-cancer activity, it induces apoptosis in HepG2 cells via accumulation of p53, alters the Bax/Bcl-2 ratio, and activates caspases, resulting in cytochrome c release from the mitochondria. A mixture of uncarinic acid E and 27-O-p-( | |||
T32326 |
Juvabione
|
||
Juvabione is the methyl ester of todomatuic acid, both of which are sesquiterpenes (C15) found in the wood of true firs of the genus Abies. They exist as part of a mixture of sesquiterpenes based on the bisabolane scaffold. Sesquiterpenes of this family, | |||
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Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-00163 |
Levanase Protein, Bacillus sp., Recombinant (His & SUMO)
2,6-beta-D-fructan fructanohydrolase,Endo-levanase,Levanase |
Bacillus | E. coli |
Catalyzes the hydrolysis of levan with endo-type specificity. The products of levan hydrolysis are a mixture of fructose and a series of fructooligosaccharides up to 12-mer, with levantriose being the major oligosaccharide obtained. Is not active towards sucrose. Levanase Protein, Bacillus sp., Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 30.3 kDa and the accession number is O31411. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TMID-0006 |
Budesonide-d8
mixture of diastereomers-d8 |
||
Budesonide-d8 是 Budesonide 的氘代化合物。Budesonide 的 CAS 号为 51333-22-3。Budesonide 是吸入型糖皮质类固醇,是一种口服具有活性的糖皮质激素受体激动剂。它能够减小肺部肿瘤的体积,逆转 DNA 低度甲基化,调节基因的 mRNA 表达。它是能够用于哮喘的抗炎药。 | |||
TMIH-0155 |
Prasugrel Metabolite Derivative-13C-d3
Mixture of Diastereomers-13C-d3 |
||
Prasugrel Metabolite Derivative-13C-d3 是 Prasugrel Metabolite Derivative 的 13C 和氘代化合物。 | |||
TMIH-0316 |
Lurasidone Inactive Metabolite 14326-d8
5β/6β-Hydroxy Lurasidone-d8 Hydrochloride (Mixture of Diastereomers) |
||
Lurasidone Inactive Metabolite 14326-d8 是 Lurasidone Inactive Metabolite 14326 的氘代化合物。Lurasidone Inactive Metabolite 14326 的 CAS 号为 186204-33-1。 | |||
TMIH-0315 |
Lurasidone Inactive Metabolite 14283-d8
5α/6α-Hydroxy Lurasidone-d8 Hydrochloride (Mixture of Diastereomers) |
||
Lurasidone Inactive Metabolite 14283-d8 是 Lurasidone Inactive Metabolite 14283 的氘代化合物。Lurasidone Inactive Metabolite 14283 的 CAS 号为 186204-31-9。 | |||
TMIH-0483 |
Ractopamine-d6 (Mixture of Diastereomers)
|
||
Ractopamine-d6 (Mixture of Diastereomers) 是 Ractopamine (Mixture of Diastereomers) 的氘代化合物。 | |||
TMIH-0426 |
Permethrin-d5 (cis/trans mixture)
|
||
Permethrin-d5 (cis/trans mixture) 是 Permethrin (cis/trans mixture) 的氘代化合物。 | |||
TMIH-0484 |
Ractopamine-d6 Hydrochloride (Mixture of Diastereomers)
|
||
Ractopamine-d6 Hydrochloride (Mixture of Diastereomers) 是 Ractopamine Hydrochloride (Mixture of Diastereomers) 的氘代化合物。 | |||
TMIH-0328 |
Menaquinone 4-d7 (Mixture of cis-trans isomers)
|
||
Menaquinone 4-d7 (Mixture of cis-trans isomers) 是 Menaquinone 4 (Mixture of cis-trans isomers) 的氘代化合物。 | |||
TMIJ-0317 |
Nadolol-d9 (Mixture of Diastereomers)
|
||
Nadolol-d9 (Mixture of Diastereomers) 是 Nadolol 的氘代化合物。Nadolol 的 CAS 号为 42200-33-9。Nadolol 是一种有机阴离子转运多肽 1A2 (OATP1A2) 的底物,是一种非选择性的、具有口服活性的 β-肾上腺素受体 (β-adrenergic receptors) 阻滞剂,可用于高血压,心绞痛和血管性头痛的研究。 | |||
TMIJ-0188 |
(±)-Voriconazole-d3 (Mixture of Enantiomers)
|
||
(±)-Voriconazole-d3 (Mixture of Enantiomers) 是 (±)-Voriconazole 的氘代化合物。(±)-Voriconazole 的 CAS 号为 188416-29-7。 | |||
TMIJ-0318 |
rac-Brivaracetam-d7 (Mixture of Diastereomers)
|
||
rac-Brivaracetam-d7 (Mixture of Diastereomers) 是 rac-Brivaracetam 的氘代化合物。rac-Brivaracetam 的 CAS 号为 357335-87-6。 | |||
TMIJ-0270 |
Pinaverium-d4 Bromide (Mixture of Diastereomers)
|
||
Pinaverium-d4 Bromide (Mixture of Diastereomers) 是 Pinaverium Bromide 的氘代化合物。Pinaverium Bromide 的 CAS 号为 53251-94-8。Pinaverium bromide 是一种具有解痉作用的钙通道阻滞剂,可有效缓解疼痛、腹泻和肠道不适。 | |||
TMID-0265 |
Dothiepin-d6 HCl (N,N-dimethyl-d6) (cis/trans mixture)
|
||
Dothiepin-d6 HCl (N,N-dimethyl-d6) (cis/trans mixture) 是 Dothiepin HCl 的氘代化合物。Dothiepin HCl 的 CAS 号为 25627-36-5。 | |||
TMIJ-0212 |
trans-Hydroxy Loxoprofen-13C-d3
|
||
trans-Hydroxy Loxoprofen-13C-d3 (Mixture of Diastereomers) 是 trans-Hydroxy Loxoprofen 的 13C 和氘代化合物。trans-Hydroxy Loxoprofen 的 CAS 号为 371753-19-4。 | |||
T38602 |
(E/Z)-Eltrombopag 13C4
(E/Z)-Eltrombopag 13C4,(E/Z)-SB-497115 13C4 |
||
(E/Z)-Eltrombopag 13C4 ((E/Z)-SB-497115 13C4) is a mixture complex of E-Eltrombopag and Z-Eltrombopag, with 13C labeled. Z-Eltrombopag is a thrombopoietin (TPO) receptor agonist developed for certain conditions that lead to thrombocytopenia. | |||
TMIH-0521 |
Silibinin-d3
|
||
Silibinin-d3 是 Silibinin 的氘代化合物。Silibinin 的 CAS 号为 22888-70-6。Silibinin 是水飞蓟的主要活性成分,具有抗癌和化疗预防作用,能抑制细胞增殖和迁移。 | |||
TMIJ-0141 |
(S)-Amlodipine-d4
|
||
(S)-Amlodipine-d4 是 (S)-Amlodipine 的氘代化合物。(S)-Amlodipine 的 CAS 号为 103129-82-4。Levamlodipine 是一种二氢吡啶钙通道阻滞剂,具有舒张血管的作用,可用于高血压和心绞痛的研究。 | |||
TMIH-0159 |
Citalopram-d6
|
||
Citalopram-d6 是 Citalopram 的氘代化合物。Citalopram 的 CAS 号为 59729-33-8。Citalopram (Lu 10-171) 是一种具有口服活性的、选择性的血清素再摄取抑制剂 (SSRI),是一种选择性5-羟色胺再摄取抑制剂,是一种 S(+)-对映体 (Escitalopram) 和 R(-)-对映体的外消旋混合物。Citalopram 具有抗抑郁活性,可增强血清素能神经传递,可用于研究老年痴呆。 | |||
TMID-0233 |
Salbutamol-d9
|
||
Salbutamol-d9 是 Salbutamol 的氘代化合物。Salbutamol 的 CAS 号为 18559-94-9。Salbutamol 是短效的 β2 肾上腺素受体激动剂,用于哮喘和慢性阻塞性肺疾病 (COPD) 引发的支气管痉挛的研究。 | |||
TMIH-0512 |
Salbutamol-d3
|
||
Salbutamol-d3 是 Salbutamol 的氘代化合物。Salbutamol 的 CAS 号为 18559-94-9。Salbutamol 是短效的 β2 肾上腺素受体激动剂,用于哮喘和慢性阻塞性肺疾病 (COPD) 引发的支气管痉挛的研究。 | |||
T35698 |
Octanoic Acid-13C
|
||
Octanoic acid-13C is intended for use as an internal standard for the quantification of octanoic acid by GC- or LC-MS. Octanoic acid is a medium-chain saturated fatty acid. It has been found in Teleme cheeses made from goat, ovine, or bovine milk.1 Octanoic acid is active against the bacteria S. mutans, S. gordonii, F. nucleatum, and P. gingivalis (IC80s = <125, <125, 1,403, and 2,294 μM, respectively).2 Levels of octanoic acid are increased in the plasma of patients with medium-chain acyl-CoA d... |