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Targets Recommended: Others

17

抑制剂 & 化合物

1

天然产物

53

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T15598 Isosulfan blue

Others Others
Isosulfan blue 是用于淋巴管造影中淋巴管识别的蓝色染料,可用于乳腺癌前哨淋巴结活检,但其在乳腺癌手术中有发生过敏反应的可能性。
T76978 Siltuximab

CNTO-328

IL Receptor Immunology/Inflammation
Siltuximab(CNTO-328) 是一种靶向 IL-6 且具有抗肿瘤活性的单克隆抗体,可用于研究巨大淋巴结增生症 (MCD) 和 COVID-19。
T27884 LY 183648

LY-183648,LY183648

Others Others
LY 183648 has antiestrogenic activity. LY117018 inhibited PAIII metastasis to the gluteal (97%) and iliac lymph nodes (88%).
T23898 Clocoumarol

Clocoumarolum,BRN 1264788,DB 112

Others Others
Clocoumarol is an anticoagulant that prevents blood clotting. It also can inhibit the dilatation of the spleen and the congestion of lymph nodes.
T41175 OB 24 hydrochloride

Others Others
OB 24 hydrochloride is a potent and selective heme oxygenase 1 (HO-1) inhibitor (IC50 values are 1.9 and >100 μM for HO-1 and HO-2 respectively), reduces protein carbonylation and reactive oxygen species formation in advanced prostate cancer cells (PCA). Inhibits cell proliferationin vitroand PCA tumor growth and lymph node/lung metastasesin vivo. Synergizes with Taxol.
T35821 CAY10721

Others Others
CAY10721 is an inhibitor of sirtuin 3 (SIRT3), a class III HDAC (39% SIRT3 inhibition at 200 μM). Upregulation of SIRT3 transcription is associated with oral squamous cell carcinoma (OSCC) and breast cancer with lymph node involvement, while SIRT3 down-regulation inhibits the growth of OSCC cells and sensitizes them to radiation and chemotherapy.
T79791 Immunosuppressant-1

Apoptosis Apoptosis
Immunosuppressant-1(Compound 31)抑制抗-CD3/抗-CD28共刺激的T细胞增殖,具备免疫抑制活性。该化合物能激活活化的淋巴结细胞中的caspase-3和PARP,从而诱导细胞凋亡(apoptosis)。
T75154 ATU027

Others Others
ATU027, 一种可沉默血管内皮中PKN3表达的siRNA, 已在小鼠癌症模型中证明能有效抑制局部肿瘤侵袭及淋巴结和肺转移。
T78458 IR 813 tosylate

IR 813 tosylate, 一近红外(NIR)荧光染料(λex=815 nm,λem=840 nm),适用于小鼠局部淋巴结的可视化。
T81400 Pritumumab

Pritumumab是一种自然源的人类IgG1kappa单克隆抗体,其最初源于一位宫颈癌患者的区域淋巴结分离得到。该单抗特异性地识别波形蛋白,该蛋白在多种恶性肿瘤细胞表面展现。Pritumumab在胶质母细胞瘤的科研应用中具有潜在价值。
T1120L2 Dacarbazine citrate

DTIC citrate

Others Others
Dacarbazine citrate is an alkylating agent used to treat cancers of the lymphatic system and malignant melanoma (a type of skin cancer) in patients with certain conditions: islet cell carcinoma (part of the pancreas) Soft tissue sarcoma (cancer of muscles
T60895 JAK-2/3-IN-3

Others Others
JAK-2/3-IN-3 (化合物 ST4j) 可用于研究淋巴源性疾病和白血病。JAK-2/3-IN-3 以时间和剂量依赖性的方式抑制JAK2的自磷酸化并诱导细胞凋亡。JAK-2/3-IN-3 是 JAK2/3 的有效抑制剂,对JAK2和JAK3的IC50值分别为 13.00 和 14.86 nM。
T37548 azido-FTY720

azido-FTY720

Others Others
FTY720 is a derivative of ISP-1 (myriocin), a fungal metabolite of the Chinese herb Iscaria sinclarii as well as a structural analog of sphingosine. It is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. FTY720 is phosphorylated by sphingosine kinase, which then acts as a potent agonist at four of the sphingosine-1-phosphate (S1P) receptors (S1P1, S1P3, S1P4, and S1P5). Down-regulation of S1P1 recept...
T36454 1-Stearoyl-rac-glycerol

Glyceryl monostearate,Monostearin

1-Stearoyl-rac-glycerol 是一种在 sn-1 位含有硬脂酸的单酰甘油。在偶氮甲烷诱发的小鼠结肠直肠癌模型中,肿瘤组织中的 1-Stearoyl-rac-glycerol水平降低。1-Stearoyl-rac-glycerol 已被用于大鼠透皮递送阿霉素的传递体的组成,导致阿霉素在淋巴结、脾脏和心脏中积聚。
T78451 Patent Blue V

Acid blue 1

Patent Blue V(Acid blue 1)是一款应用于眼科的新型生物染料,特别是在进行视网膜切除手术时,用以染色以便去除内限制膜(ILM)。该染料在玻璃体视网膜手术中确保了对视网膜结构的有效标记,从而实现精确去除。光谱分析揭示,Patent Blue V在450 nm以下和600 nm以上具有强烈的吸收特性,展现蓝绿色。此外,它亦作为淋巴管造影术中的追踪剂,在染色活检手术中使用以助于淋巴结的切除。
T83910 S1PL-IN-31

Sphingosine-1-Phosphate Lyase Inhibitor 31,S1PL Inhibitor 31,S1P Lyase Inhibitor 31

Others Others
S1PL-IN-31是一种鞘氨醇-1-磷酸(S1P)裂解酶的抑制剂(IC50 = 210 nM),同时也是Smoothened(Smo)受体的对抗剂(IC50 = 440 nM)。在体内,S1PL-IN-31 (每天2 mg/kg)能够防止实验性自身免疫性脑炎(EAE)模型大鼠中,由髓鞘少突胶质细胞糖蛋白(MOG)肽段MOG29-152诱发的颈部及胸部淋巴细胞渗透和神经肌肉虚弱。该化合物降低了大鼠的淋巴细胞总数及CD4+ T细胞、CD8+ T细胞和B细胞的水平。S1PL-IN-31 (每天3及10 mg/kg剂量)在雄性和雌性大鼠心脏和淋巴结中增加了S1P水平,并且在雌性大鼠中降低了心率。
T35829 CC-90005

Others Others
CC-90005 is a potent, selective and orally active inhibitor of protein kinase C-θ (PKC-θ), with an IC50 of 8 nM. CC-90005 shows selectivity for PKC-θ over PKC-δ (IC50=4440 nM). CC-90005 can inhibit T cell activation by IL-2 expression[1]. CC-90005 shows the exquisite selectivity of CC-90005, with IC50s for all other family members of >3 μM[1].CC-90005 is a moderate inhibitor of both CYP2C9 (IC50=8 μM) and CYP2C19 (IC50=5.9 μM) in human liver microsomes[1].CC-90005 inhibits IL-2 expression in LRS...

化合物

Isosulfan blue
Cat.No: T15598
Synonym:
Target: Others
Siltuximab
Cat.No: T76978
Synonym: CNTO-328
Target: IL Receptor
LY 183648
Cat.No: T27884
Synonym: LY-183648,LY183648
Target: Others
Clocoumarol
Cat.No: T23898
Synonym: Clocoumarolum,BRN 1264788,DB 112
Target: Others
OB 24 hydrochloride
Cat.No: T41175
Synonym:
Target: Others
CAY10721
Cat.No: T35821
Synonym:
Target: Others
Immunosuppressant-1
Cat.No: T79791
Synonym:
Target: Apoptosis
ATU027
Cat.No: T75154
Synonym:
Target: Others
IR 813 tosylate
Cat.No: T78458
Synonym:
Target:
Pritumumab
Cat.No: T81400
Synonym:
Target:
Dacarbazine citrate
Cat.No: T1120L2
Synonym: DTIC citrate
Target: Others
JAK-2/3-IN-3
Cat.No: T60895
Synonym:
Target: Others
azido-FTY720
Cat.No: T37548
Synonym: azido-FTY720
Target: Others
1-Stearoyl-rac-glycerol
Cat.No: T36454
Synonym: Glyceryl monostearate,Monostearin
Target:
Patent Blue V
Cat.No: T78451
Synonym: Acid blue 1
Target:
S1PL-IN-31
Cat.No: T83910
Synonym: Sphingosine-1-Phosphate Lyase Inhibitor 31,S1PL Inhibitor 31,S1P Lyase Inhibitor 31
Target: Others
CC-90005
Cat.No: T35829
Synonym:
Target: Others
Cat. No. Product Name Target Signaling Pathways
T5S1550 Cinnamyl alcohol

肉桂醇,肉桂醇;beta-苯丙烯醇,Cinnamic Alcohol,Styryl Carbinol

PPAR DNA Damage/DNA Repair; Metabolism
Cinnamyl alcohol (Styryl Carbinol) 是从板栗花中分离得到的一种活性成分,抑制增加的 PPARγ表达,具有抗肥胖作用。

天然产物

Cinnamyl alcohol
Cat.No: T5S1550
Synonym: 肉桂醇,肉桂醇;beta-苯丙烯醇,Cinnamic Alcohol,Styryl Carbinol
Target: PPAR
Cat. No. Product Name Species Expression System
TMPH-00003 LASP1 Protein, Human, Recombinant (His)

LIM and SH3 domain protein 1,Metastatic lymph node ...

Human P. pastoris (Yeast)
LASP1 Protein, Human, Recombinant (His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 31.2 kDa; 43 kDa, reducing conditions and the accession number is Q14847.
TMPJ-00778 HER2/ERBB2 Protein, Human, Recombinant (His)

TKR1,Metastatic lymph node gene 19 protein,ERBB2,Pr...

Human HEK293 Cells
HER2/ERBB2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 90-120 KDa and the accession number is P04626.
TMPJ-00776 HER2/ERBB2 Protein, Human, Recombinant (hFc & Avi), Biotinylated

Tyrosine kinase-type cell surface receptor HER2,NGL,EGFR2,TK...

Human HEK293 Cells
HER2/ERBB2 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Fc-Avi tag. The predicted molecular weight is 120-140 KDa and the accession number is P04626.
TMPJ-00777 HER2/ERBB2 Protein, Human, Recombinant (aa 23-652, hFc)

TKR1,Proto-oncogene Neu,EGFR2,Tyrosine kinase-type cell surf...

Human HEK293 Cells
HER2/ERBB2 Protein, Human, Recombinant (aa 23-652, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 120-145 KDa and the accession number is P04626.
TMPY-03905 Lymphotactin/XCL1 Protein, Canine, Recombinant (His)

chemokine (C motif) ligand 1

Canine Baculovirus Insect Cells
Lymphotactin/XCL1 Protein, Canine, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 11.34 kDa and the accession number is A0A8C0PT44.
TMPH-02413 Lymphocytic choriomeningitis virus (LCMV) (strain Armstrong) GPC Protein (His & SUMO)

GPC,Pre-glycoprotein polyprotein GP complex

LCMV E. coli
Lymphocytic choriomeningitis virus (LCMV) (strain Armstrong) GPC Protein (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 42.4 kDa and the accession number is P09991.
TMPH-02412 Lymphocytic choriomeningitis virus (LCMV) (strain WE) GPC Protein (His & Myc)

Pre-glycoprotein polyprotein GP complex,GPC

LCMV E. coli
Lymphocytic choriomeningitis virus (LCMV) (strain WE) GPC Protein (His & Myc) is expressed in E. coli expression system with N-6xHis and C-Myc tag. The predicted molecular weight is 30.9 kDa and the accession number is P07399.
TMPY-00248 Lymphotoxin Beta Protein, Cynomolgus, Recombinant (His)

Lymphotoxin β,lymphotoxin β (TNF superfami...

Cynomolgus Baculovirus Insect Cells
LTB (Lymphotoxin Beta) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. Heat-labile enterotoxin B subunit (LTB) of enterotoxigenic Escherichia coli (ETEC) is both a strong mucosal adjuvant and immunogen. It is a subunit vaccine candidate to be used against ETEC-induced diarrhea. It has already been expressed in seve...
TMPY-02610 Lymphotactin/XCL1 Protein, Mouse, Recombinant (His)

SCM-1a,AI661682,chemokine (C motif) ligand 1,SCM-1,LTN,ATAC,...

Mouse Baculovirus Insect Cells
Lymphotactin/XCL1 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 11.5 kDa and the accession number is P47993.
TMPY-02755 Lymphotactin/XCL1 Protein, Cynomolgus, Recombinant (His)

chemokine (C motif) ligand 1

Cynomolgus Baculovirus Insect Cells
Lymphotactin/XCL1 Protein, Cynomolgus, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 11.6 kDa.
TMPY-02687 Lymphotactin/XCL1 Protein, Human, Recombinant (His)

SCM1,SCM-1,SCYC1,LTN,LPTN,SCM-1a,ATAC,SCM1A,chemokine (C mot...

Human Baculovirus Insect Cells
Lymphotactin/XCL1 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 11.6 kDa and the accession number is P47992.
TMPY-00322 DEC-205 Protein, Human, Recombinant (His)

GP200-MR6,CD205,CLEC13B,lymphocyte antigen 75,LY-75...

Human HEK293 Cells
LY75 (Lymphocyte Antigen 75) is a Protein Coding gene. It is broadly expressed in the lymph node, appendix, and other tissues. LY75 knockdown in SKOV3 cells resulted in predominant upregulation of functional pathways implicated in cell proliferation and metabolism, while pathways associated with cell signaling and adhesion, complement activation, and immune response were mostly suppressed. Moreover, LY75 suppression had an opposite effect on EOC cell lines with the epithelial phenotype (A2780s a...
TMPK-00293 Nectin-2 Protein, Human, Recombinant (His & Avi)

PRR2,CD112,Nectin2,MPH,PVRR2,PVRL2,HVEB

Human HEK293 Cells
Nectin-2 is an adhesion molecule that has been reported to play a role in tumor growth, metastasis and tumor angiogenesis. Nectin-2 expression in ovarian cancer may support tumor cell adhesion, leading to growth and lymph node metastasis. Effect of VEGF on Nectin-2 expression as well as permeability was investigated in HUVEC.
TMPJ-01319 TINAGL1 Protein, Human, Recombinant (His)

LCN7,Tubulointerstitial nephritis antigen-like (TINAGL1),Oxi...

Human HEK293 Cells
TINAGL1 is a secreted protein and contains one SMB (somatomedin-B) domain. TINAGL1 is expressed in aorta, lymph nodes, heart, bone marrow, placenta, lung, kidney, skeletal muscle, pancreas, thyroid, adrenal gland and so on. TINAGL1 may be implicated in the adrenocortical zonation and in mechanisms for repressing the CYP11B1 gene expression in adrenocortical cells.
TMPJ-00665 ADAMDEC1 Protein, Human, Recombinant (His)

a disintegrin and metalloproteinase domain-like protein decy...

Human HEK293 Cells
ADAM DEC1 protein is expressed highly in the small intestine and appendix, moderately in lymph node, mucosal lining of the colon, thymus, spleen and very weakly in the bone marrow. ADAM DEC1 is induced during DC maturation and up-regulated in response to T-cell signals. It may play an important role in the control of the immune response and during pregnancy.
TMPK-00529 EPHA5 Protein, Cynomolgus, Recombinant (His)

EHK-1,BSK,Rek7,EK7,EphA5,HEK7,TYRO4,TYRO4HEK7CEK7,EHK1

Cynomolgus HEK293 Cells
Ephrin type-A receptor 5 (EphA5) expression was detected in all non-tumor gastric epithelia but was differentially expressed among gastric cancer samples. EphA5 is differentially expressed in gastric cancer. EphA5 may therefore be a potential therapeutic target and may have clinical utility as a marker for lymph node metastasis in gastric cancer. EPHA5 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 61.73 kDa and the...
TMPK-00899 EPHA5 Protein, Human, Recombinant (His)

HEK7,EK7,Rek7,EphA5,EHK1,TYRO4HEK7CEK7,TYRO4,BSK,EHK-1

Human HEK293 Cells
Ephrin type-A receptor 5 (EphA5) expression was detected in all non-tumor gastric epithelia but was differentially expressed among gastric cancer samples. EphA5 is differentially expressed in gastric cancer. EphA5 may therefore be a potential therapeutic target and may have clinical utility as a marker for lymph node metastasis in gastric cancer. EPHA5 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 61.9 kDa and the acces...
TMPY-01584 PR-Set7 Protein, Human, Recombinant

SET8,SET07,PR-Set7,SET domain containing (lysine methyltrans...

Human E. coli
KMT5A (known as PR-Set7/9, SETD8 and SET8), a member of the SET domain containing methyltransferase family specifically targeting H4K20 for methylation, has been implicated in multiple biological processes. Inhibition of KMT5A attenuated proliferation and induced apoptosis. Elevated KMT5A expression was significantly correlated with extrathyroidal extension, lymph node metastasis and advanced pathological stage of papillary thyroid cancer. KMT5A may be a novel oncogenic factor, specifically a re...
TMPJ-01222 LRRC25 Protein, Human, Recombinant (His)

Leucine-rich repeat-containing protein 25,MAPA,Monocyte and ...

Human HEK293 Cells
Leucine-rich repeat-containing protein 25(LRRC25) is a single-pass type I membrane protein and contains 3 LRR (leucine-rich) repeats. The protein expressed in plasmacytoid dendritic cells (PDC), monocyte-derived dendritic cells (MDDC), granulocytes, monocytes, B-lymphocytes, peripheral blood leukocytes, spleen, bone marrow, and, to a lesser extent, lymph nodes, fetal liver, and appendix but not in thymus. The protein may be involved in the activation of cells of innate and acquired immunity.
TMPJ-01186 TRIM Protein, Human, Recombinant (His)

pp29/30,TRIM,HSPC062,TCRIM,TRAT1,T-Cell Receptor-Interacting...

Human E. coli
T-Cell Receptor-Associated Transmembrane Adapter 1 (TRAT1) is a single-pass type III membrane protein. TRAT1 exists as a disulfide-linked homodimer and is strongly expressed in the thymus, and to a lesser extent in the spleen, lymph node, and peripheral blood lymphocytes. TRAT1 is phosphorylated on tyrosines by LCK or FYN upon TCR activation. Its function is to stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells.
TMPK-01079 PLD4 Protein, Mouse, Recombinant (His)

Choline phosphatase 4,5'-3' exonuclease PLD4,Phospholipase D...

Mouse HEK293 Cells
Phospholipase D4 (PLD4) is a newly identified protein expressed in microglia. the expression of PLD4 was located in macrophages in the colon cancer mesenchymal and lymph nodes as shown by immunohistochemical analysis. furthermore, its expression was associated with clinical staging of colon cancer. Then, THP-1 as a cell model induced into TAMs. PLD4 could be involved in the activation process of M1 phenotype macrophages. PLD4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cel...
TMPK-01138 PLD4 Protein, Human, Recombinant (His)

5'-3' exonuclease PLD4,PLD 4,Phospholipase D4,Choline phosph...

Human HEK293 Cells
Phospholipase D4 (PLD4) is a newly identified protein expressed in microglia. the expression of PLD4 was located in macrophages in the colon cancer mesenchymal and lymph nodes as shown by immunohistochemical analysis. furthermore, its expression was associated with clinical staging of colon cancer. Then, THP-1 as a cell model induced into TAMs. PLD4 could be involved in the activation process of M1 phenotype macrophages. PLD4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cel...
TMPY-01718 Serpin B12 Protein, Mouse, Recombinant (His)

2300003F07Rik,4833409F13Rik,serpin peptidase inhibitor, clad...

Mouse Baculovirus Insect Cells
Serpins are the largest and most diverse family of serine protease inhibitors which are involved in some fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner. Most serpins are secreted and attain physiologic concentrations in the blood and extracellular fluids. Mouse SerpinB12 is a cytoplasm protein that belongs to the serpin family and Ov-serpin subfamily. It ...
TMPY-03873 CLEC4B2 Protein, Rat, Recombinant (His)

Aplra1,CLEC4B2,C-type lectin domain family 4, member b2

Rat HEK293 Cells
Clec4b2, also known as mDCAR1, is a member of the DCIR/DCAR family. Expression of Clec4b2 was strongly tissue dependent. Clec4b2 expression on DCs was restricted to the CD8(+) DC subset in spleen and thymus and on subpopulations of CD11b(+) myeloid cells in bone marrow and spleen, whereas the molecule was not detectable on both cell types in lymph nodes and peripheral blood. Clec4b2 is a functional receptor on cells of the immune system and provides further insights into the regulation of immune...
TMPJ-00902 Kell Protein, Human, Recombinant (His)

CD238,KEL,Kell blood group glycoprotein

Human HEK293 Cells
Kell blood group glycoprotein (KEL) is a single-pass type II membrane protein which belongs to the peptidase M13 family. It is expressed in Expressed at high levels in erythrocytes and testis, and, at lower levels, in skeletal muscle, tonsils, lymph node, spleen and appendix. KEL has been shown zinc endopeptidase with endothelin-3-converting enzyme activity. It cleaves EDN1, EDN2 and EDN3, with a marked preference for EDN3. It links via a single disulfide bond to the XK membrane protein that car...
TMPJ-01365 SLAMF8 Protein, Human, Recombinant (His)

CD353,SLAM family member 8,BCM-like membrane protein,B-l...

Human HEK293 Cells
SLAM family member 8 (SLAMF8) is a single-pass type I membrane protein and contains 1 Ig-like C2-type domain. SLAMF8 is a member of the CD2 family of cell surface proteins involved in lymphocyte activation. These proteins are characterized by Ig domains and studies of a similar protein in mouse suggest that it may function during B cell lineage commitment. SLAMF8 is expressed in lymph node, spleen, thymus and bone marrow. It may play a role in B-lineage commitment and/or modulation of signaling...
TMPJ-00617 IL-33 Protein, Rhesus macaque, Recombinant (His)

Interleukin-33,IL1F11,IL33,白介素,白细胞介素,IL-1F11,Interleukin-1 F...

Rhesus E. coli
Interleukin-33 (IL-33) belongs to the IL-1 superfamily. IL33 is highly expressed in endothelial venules found in tonsils, Peyer patches and mesenteric lymph nodes, but almost undetectable in placenta. IL33 induces the production of T helper-2 (Th2)-associated cytokines. IL-33 is a cytokine that mediates its biological effects by binding to and signals through IL1RL1/ST2 and IL-1 Receptor Accessory Protein (IL1RAP), activating intracellular molecules in the NF-κB and MAP kinase signaling pathways...
TMPY-03751 C1orf33/MRTO4 Protein, Human, Recombinant (His)

MRT4,dJ657E11.4,C1orf33,MRT4 homolog, ribosome maturation fa...

Human E. coli
MRTO4 (MRT4 Homolog, Ribosome Maturation Factor) is a Protein Coding gene. MRTO4, also known as MRT4, belongs to the universal ribosomal protein uL10 family. This gene encodes a protein sharing a low level of sequence similarity with ribosomal protein P0. MRTO4 is a nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. The precise function of MRTO4 is c...
TMPY-04375 Casein Kinase 1 alpha Protein, Human, Recombinant (GST)

CKIa,casein kinase 1, alpha 1,casein kinase 1, α1,CK1a,Casei...

Human Baculovirus Insect Cells
Casein kinase I isoform alpha, also known as CKI-alpha, CK1 and CSNK1A1, is a cytoplasm protein which belongs to theprotein kinase superfamily, CK1 Ser/Thr protein kinase family and casein kinase I subfamily. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. High expression of CSNK2A1, or concomitantly high expression of CSNK2A1, are independent prognostic factors of poor survival in NSCLC patients. CSNK2A1 are use...
TMPJ-01328 ZBP1 Protein, Human, Recombinant (His)

Tumor Stroma and Activated Macrophage Protein DLM,DLM1,Z-DNA...

Human E. coli
Z-DNA Binding Protein 1 (ZBP1) is a protein with 2 DRADA repeats. ZBP1 is highly expressed in lymphatic tissues including lymph node, leukocytes, tonsil, bone marrow, and spleen. ZBP1 participates in the detection of viral and bacterial DNA from by the host's innate immune system. It plays a role in host defense against tumors and pathogens. ZBP1 Acts as a cytoplasmic DNA sensor which, when activated, induces the recruitment of TBK1 and IRF3 to its C-terminal region and activates the downstream ...
TMPJ-00533 LYVE1 Protein, Human, Recombinant (His)

XLKD1,Cell Surface Retention Sequence-Binding Protein 1,Extr...

Human HEK293 Cells
Lymphatic Vessel Endothelial Hyaluronic Acid Receptor 1 is a single-pass type I membrane protein. LYVE-1 is a CD44 homolog found primarily on lymphatic endothelial cells 1. LYVE-1 mainly expressed in endothelial cells lining lymphatic vessels. While LYVE-1 functions is a Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. LYVE-1 plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention s...
TMPJ-00349 RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, His)

CD265 antigen,FEO,TRANCER,ODFR,ODFROSTS,TRANCE R,TNFRSF11A,O...

Human HEK293 Cells
Receptor Activator of Nuclear Factor κ B (RANK), also known as CD265, TRANCE Receptor or TNFRSF11A, is member of the tumor necrosis factor receptor (TNFR) molecular superfamily. RANK is the receptor for RANK-Ligand (RANKL) and part of the RANK/RANKL/OPG signaling pathway that regulates osteoclast differentiation and activation. It plays a vital role in bone remodeling and repair, immune cell function, lymph node development, thermal regulation, and mammary gland development. RANK is constitutive...
TMPJ-00272 RELT/TNFRSF19L Protein, Human, Recombinant (hFc)

RELT,TNFRSF19L,Receptor expressed in lymphoid tissu...

Human HEK293 Cells
Tumor necrosis factor receptor superfamily member 19L (TNFRSF19L), also known as Receptor expressed in lymphoid tissues and RELT, is a member of the TNF-receptor superfamily. TNFRSF19L is a single-pass type membrane protein and contains one TNFR-Cys repeat. TNFRSF19L is highly expressed in spleen, lymph node, thymus, peripheral blood leukocytes, bone marrow and fetal liver. It has been shown TNFRSF19L activates the NF-kappaB pathway and selectively binds TNF receptor-associated factor 1 (TRAF1)....
TMPJ-01282 Serpin B12 Protein, Human, Recombinant (His)

SERPINB12,Serine Protease Inhibitor-clade B12,Serpin B12

Human HEK293 Cells
Serpin B12 is a member of the serpin family. Serpins are the largest and most diverse family of serine protease inhibitors. Most serpins are secreted and attain physiologic concentrations in the blood and extracellular fluids. Serpin B12 is expressed in many tissues, including brain, bone marrow, lymph node, heart, lung, liver, pancreas, testis, ovary, and intestine. Serpins are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysi...
TMPJ-01323 NTAL Protein, Human, Recombinant (His)

Williams-Beuren Syndrome Chromosomal Region 5 P,Membrane-Ass...

Human HEK293 Cells
Linker for Activation of T-Cells Family Member 2 (LAT2) is a single-pass type III membrane protein. LAT2 is highly expressed in the spleen, peripheral blood lymphocytes, and germinal centers of lymph nodes. LAT2 is involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. It may also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. ...
TMPJ-00120 NKp80/KLRF1 Protein, Human, Recombinant (His)

Lectin-like receptor F1,C-type lectin domain family 5 member...

Human HEK293 Cells
Killer cell lectin-like receptor subfamily F member 1 (KLRF1) is known as NKp80. Human NKp80, a member of the C-type lectin family of proteins (1 - 3), is 231 aa in length with a 38 amino acid (aa) cytoplasmic region, a 21 aa transmembrane region, and a 172 aa extracellular domain (ECD). The protein strongly expressed in peripheral blood leukocytes and spleen, with weaker expression in lymph node and adult liver, and no expression detected in bone marrow, thymus, and fetal liver. Its' function i...
TMPY-04073 MRPL44 Protein, Human, Recombinant (His)

mitochondrial ribosomal protein L44,COXPD16,L44MT,MRP-L44

Human Baculovirus Insect Cells
MRPL44 (Mitochondrial Ribosomal Protein L44) is a Protein Coding gene. MRPL44 encodes a protein in the large subunit of the mitochondrial ribosome and is suggested to locate near the tunnel exit of the yeast mitochondrial ribosome. It belongs to the mitochondrion-specific ribosomal protein mL44 subfamily. In the patient fibroblasts, decreased MRPL44 affected assembly of the large ribosomal subunit and stability of 16S rRNA leading to complex IV deficiency. It may have a function in the assembly/...
TMPY-06748 UBA6 Protein, Human, Recombinant (GST)

ubiquitin-like modifier activating enzyme 6,UBE1L2,MOP-4,E1-...

Human Baculovirus Insect Cells
UBA6 (Ubiquitin Like Modifier Activating Enzyme 6) is a Protein Coding gene. The UBA6 gene, located on 4q13.2, is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and frog. Uba6 is a homolog of the ubiquitin-activating enzyme, Uba1, and activates two ubiquitin-like proteins (UBLs), ubiquitin and FAT10. UBA6 is an alternative enzyme for ubiquitin activation in vertebrates that plays a pivotal role in early mouse development. UBA6 is widely expressed in the lymph n...
TMPY-04476 MVK Protein, Human, Recombinant (His & GST)

POROK3,LRBP,MVLK,MK,mevalonate kinase

Human Baculovirus Insect Cells
Mevalonate kinase belongs to the GHMP kinase family, Mevalonate kinase subfamily. It can be found in a wide variety of organisms from bacteria to mammals. Mevalonate kinase may be a regulatory site in the cholesterol biosynthetic pathway. Defects in mevalonate kinase can cause mevalonic aciduria (MEVA). It is an accumulation of mevalonic acid which causes a variety of symptoms such as psychomotor retardation, dysmorphic features, cataracts, hepatosplenomegaly, lymphadenopathy, anemia, hypotonia,...
TMPY-04269 LAP3 Protein, Human, Recombinant (His)

HEL-S-106,leucine aminopeptidase 3,PEPS,LAP,LAPEP

Human HEK293 Cells
LAP3 (Leucine Aminopeptidase 3) is a Protein Coding gene. 2 alternative initiation human isoforms have been reported. LAP3, belonging to the peptidase M17 family, has been proved to catalyze the hydrolysis of leucine residues. It catalyzes the removal of unsubstituted N-terminal amino acids from various peptides and is presumably involved in the processing and regular turnover of intracellular proteins. Leucine aminopeptidases are involved in many pathological disorders and regulate cell prolife...
TMPJ-00698 BTNL2 Protein, Mouse, Recombinant (His)

Ng9,Butyrophilin-like protein 2,Btnl2,Gm315

Mouse HEK293 Cells
Butyrophilin-like 2 (BTNL2) is a member of the BTN/MOG Ig-superfamily and functions as a negative regulator of immune cell activation. Mouse BTNL2 is type I transmembrane glycoprotein that contains an extracellular domain (ECD), a transmembrane region and a short cytoplasmic domain. The ECD features two V-type Ig-like domains, two C-type Ig-like domains, and four glycosylation sites. BTNL2 is expressed in epithelial cells of the small intestine, colonic dendritic cells, and in cells of the lymph...
TMPJ-00845 CTSE Protein, Human, Recombinant (His)

CTSE,Cathepsin E

Human HEK293 Cells
Cathepsin E (CTSE) is a gastric aspartyl protease that functions as a disulfide-linked homodimer. It is a member of the Peptidase C1 family, and has a specificity similar to that of Pepsin A and Cathepsin D. CTSE is localized to the endoplasmic reticulum and Golgi apparatus, while the mature enzyme is localized to the endosome. It is expressed abundantly in the stomach, the Clara cells of the lung and activated B-lymphocytes, and at lower levels in lymph nodes, skin and spleen. CTSE is an intrac...
TMPY-03521 DcR3 Protein, Human, Recombinant (hFc)

DCR3,tumor necrosis factor receptor superfamily member 6b,M6...

Human Baculovirus Insect Cells
Tumor necrosis factor receptor superfamily member 6B (TNFRSF6B) also known as DcR3(Decoy Receptor 3) and M68 is the tumor necrosis factor receptor superfamily. DcR3/TNFRSF6B belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Over-expression of this gene has been noted in gastrointestinal tract tu...
TMPY-04380 DYRK3 Protein, Human, Recombinant (His & GST)

REDK,RED,DYRK5,dual-specificity tyrosine-(Y)-phosphorylation...

Human Baculovirus Insect Cells
Dual specificity tyrosine-phosphorylation-regulated kinase 3, also known as Regulatory erythroid kinase, REDK and DYRK3, is a nucleus protein which belongs to theprotein kinase superfamily, CMGC Ser/Thr protein kinase family and MNB/DYRK subfamily. DYRKs are an emerging family of dual-specificity kinases that play key roles in cell proliferation, survival, and development. DYRK3 contains oneprotein kinase domain. Isoform 1 and isoform 2 of DYRK3 are highly expressed in testis and in hemat...
TMPY-02983 LYVE1 Protein, Mouse, Recombinant (hFc)

1200012G08Rik,Lyve-1,lymphatic vessel endothelial h...

Mouse HEK293 Cells
LYVE1, also known as LYVE-1, is a type I integral membrane glycoprotein. It contains 1 Link domain and is mainly expressed in endothelial cells lining lymphatic vessels. LYVE1 acts as a receptor and binds to both soluble and immobilized hyaluronan. It may function in lymphatic hyaluronan transport and have a role in tumor metastasis. LYVE1 also is a cell surface receptor on lymphatic endothelial cells that can be used as a lymphatic endothelial cell marker, and sort these cells for experimental ...
TMPJ-01316 IL-21 Protein, Mouse, Recombinant (His)

白细胞介素,IL-21,Interleukin-21,白介素,IL21

Mouse E. coli
Interleukin-21(IL-21) is an approximately 14 kDa cytokine which belongs to the IL-15/IL-21 family. Mature mouse IL-21 shares 66%,59%, 58%, and 88% aa sequence identity with mature canine, human, rabbit, and rat IL-21, respectively. IL-21 is produced by activated T follicular helper cells (Tfh), Th17 cells, and NKT cells. It exerts its biological effects through a heterodimeric receptor complex (IL-21 specific IL-21 R). IL-21 is a cytokine that has potent regulatory effects on cells of the immun...
TMPY-01707 CHST15 Protein, Human, Recombinant (His)

BRAG,carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulf...

Human HEK293 Cells
Carbohydrate sulfotransferase 15, also known as N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase, GalNAc4S-6ST, B-cell RAG-associated gene protein, CHST15 and BRAG, is a single-pass type II membrane protein which belongs to thesulfotransferase 1 family. CHST15 / BRAG is expressed in B-cell-enriched tissues but not in fetal or adult thymus. It is expressed in fetal and adult spleen, lymph node, tonsil, bone marrow and peripheral leukocytes. It is not expressed in T-cells. In pro-B, pre...
TMPY-01831 SLAMF8 Protein, Mouse, Recombinant (His)

Blame,SBBI42,SLAM family member 8,5830408F06Rik

Mouse HEK293 Cells
The signaling lymphocyte activation molecule (SLAM) family includes homophilic and heterophilic receptors that modulate both adaptive and innate immune responses. These receptors share a common ectodomain organization: a membrane-proximal immunoglobulin constant domain and a membrane-distal immunoglobulin variable domain that is responsible for ligand recognition. SLAM family of receptors is expressed by a wide range of immune cells. Through their cytoplasmic domain, SLAM family receptors associ...
TMPY-02386 PTP4A2 Protein, Human, Recombinant (GST)

HNMT-S2,PRL-2,HNMT-S1,protein tyrosine phosphatase type IVA,...

Human E. coli
PRL-2 (Protein-tyrosine phosphatase of regenerating liver 2), also known as PTP4A2 (Protein tyrosine phosphatase type IVA, member 2), is a member of PTP family and has an important function in controlling cell growth. PRL-2 phosphatases may be multifunctional enzymes with diverse roles in a variety of tissue and cell types. The phosphatase of regenerating liver (PRL) family, comprising PRL-1, PRL-2 and PRL-3, is a group of prenylated phosphatases that are candidate cancer biomarkers and therapeu...
TMPY-01246 MARCO Protein, Mouse, Recombinant (His)

AI323439,Ly112,macrophage receptor with collagenous structur...

Mouse HEK293 Cells
Macrophage receptor MARCO, also known as Macrophage receptor with collagenous structure and Marco, is a single-pass type II membrane protein. MARCO is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. It is expressed in subpopulations of macrophages in the spleen and the medullary cord of lymph nodes. Although it is expressed on subsets of macrophages, it can be upregulated on other macrophages after bacterial infection. The strategic positi...
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重组蛋白

LASP1 Protein, Human, Recombinant (His)
Cat.No: TMPH-00003
Species: Human
Expression System: P. pastoris (Yeast)
HER2/ERBB2 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00778
Species: Human
Expression System: HEK293 Cells
HER2/ERBB2 Protein, Human, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPJ-00776
Species: Human
Expression System: HEK293 Cells
HER2/ERBB2 Protein, Human, Recombinant (aa 23-652, hFc)
Cat.No: TMPJ-00777
Species: Human
Expression System: HEK293 Cells
Lymphotactin/XCL1 Protein, Canine, Recombinant (His)
Cat.No: TMPY-03905
Species: Canine
Expression System: Baculovirus Insect Cells
Lymphocytic choriomeningitis virus (LCMV) (strain Armstrong) GPC Protein (His & SUMO)
Cat.No: TMPH-02413
Species: LCMV
Expression System: E. coli
Lymphocytic choriomeningitis virus (LCMV) (strain WE) GPC Protein (His & Myc)
Cat.No: TMPH-02412
Species: LCMV
Expression System: E. coli
Lymphotoxin Beta Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPY-00248
Species: Cynomolgus
Expression System: Baculovirus Insect Cells
Lymphotactin/XCL1 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02610
Species: Mouse
Expression System: Baculovirus Insect Cells
Lymphotactin/XCL1 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPY-02755
Species: Cynomolgus
Expression System: Baculovirus Insect Cells
Lymphotactin/XCL1 Protein, Human, Recombinant (His)
Cat.No: TMPY-02687
Species: Human
Expression System: Baculovirus Insect Cells
DEC-205 Protein, Human, Recombinant (His)
Cat.No: TMPY-00322
Species: Human
Expression System: HEK293 Cells
Nectin-2 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00293
Species: Human
Expression System: HEK293 Cells
TINAGL1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01319
Species: Human
Expression System: HEK293 Cells
ADAMDEC1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00665
Species: Human
Expression System: HEK293 Cells
EPHA5 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00529
Species: Cynomolgus
Expression System: HEK293 Cells
EPHA5 Protein, Human, Recombinant (His)
Cat.No: TMPK-00899
Species: Human
Expression System: HEK293 Cells
PR-Set7 Protein, Human, Recombinant
Cat.No: TMPY-01584
Species: Human
Expression System: E. coli
LRRC25 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01222
Species: Human
Expression System: HEK293 Cells
TRIM Protein, Human, Recombinant (His)
Cat.No: TMPJ-01186
Species: Human
Expression System: E. coli
PLD4 Protein, Mouse, Recombinant (His)
Cat.No: TMPK-01079
Species: Mouse
Expression System: HEK293 Cells
PLD4 Protein, Human, Recombinant (His)
Cat.No: TMPK-01138
Species: Human
Expression System: HEK293 Cells
Serpin B12 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01718
Species: Mouse
Expression System: Baculovirus Insect Cells
CLEC4B2 Protein, Rat, Recombinant (His)
Cat.No: TMPY-03873
Species: Rat
Expression System: HEK293 Cells
Kell Protein, Human, Recombinant (His)
Cat.No: TMPJ-00902
Species: Human
Expression System: HEK293 Cells
SLAMF8 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01365
Species: Human
Expression System: HEK293 Cells
IL-33 Protein, Rhesus macaque, Recombinant (His)
Cat.No: TMPJ-00617
Species: Rhesus
Expression System: E. coli
C1orf33/MRTO4 Protein, Human, Recombinant (His)
Cat.No: TMPY-03751
Species: Human
Expression System: E. coli
Casein Kinase 1 alpha Protein, Human, Recombinant (GST)
Cat.No: TMPY-04375
Species: Human
Expression System: Baculovirus Insect Cells
ZBP1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01328
Species: Human
Expression System: E. coli
LYVE1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00533
Species: Human
Expression System: HEK293 Cells
RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, His)
Cat.No: TMPJ-00349
Species: Human
Expression System: HEK293 Cells
RELT/TNFRSF19L Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00272
Species: Human
Expression System: HEK293 Cells
Serpin B12 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01282
Species: Human
Expression System: HEK293 Cells
NTAL Protein, Human, Recombinant (His)
Cat.No: TMPJ-01323
Species: Human
Expression System: HEK293 Cells
NKp80/KLRF1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00120
Species: Human
Expression System: HEK293 Cells
MRPL44 Protein, Human, Recombinant (His)
Cat.No: TMPY-04073
Species: Human
Expression System: Baculovirus Insect Cells
UBA6 Protein, Human, Recombinant (GST)
Cat.No: TMPY-06748
Species: Human
Expression System: Baculovirus Insect Cells
MVK Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04476
Species: Human
Expression System: Baculovirus Insect Cells
LAP3 Protein, Human, Recombinant (His)
Cat.No: TMPY-04269
Species: Human
Expression System: HEK293 Cells
BTNL2 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00698
Species: Mouse
Expression System: HEK293 Cells
CTSE Protein, Human, Recombinant (His)
Cat.No: TMPJ-00845
Species: Human
Expression System: HEK293 Cells
DcR3 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-03521
Species: Human
Expression System: Baculovirus Insect Cells
DYRK3 Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04380
Species: Human
Expression System: Baculovirus Insect Cells
LYVE1 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-02983
Species: Mouse
Expression System: HEK293 Cells
IL-21 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-01316
Species: Mouse
Expression System: E. coli
CHST15 Protein, Human, Recombinant (His)
Cat.No: TMPY-01707
Species: Human
Expression System: HEK293 Cells
SLAMF8 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01831
Species: Mouse
Expression System: HEK293 Cells
PTP4A2 Protein, Human, Recombinant (GST)
Cat.No: TMPY-02386
Species: Human
Expression System: E. coli
MARCO Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01246
Species: Mouse
Expression System: HEK293 Cells
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