搜索结果

Search Results for " gut-microbial "

天然产物

化合物库

重组蛋白

同位素标记化合物

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name
L2540	肠道微生物代谢化合物库		614 compounds
	614 种肠道微生物代谢物的集合，可以用于高通量和高内涵筛选；

化合物库

肠道微生物代谢化合物库

Cat.No: L2540

Compounds: 614

Cat. No.	Product Name	Target	Signaling Pathways
TN7108	Urolithin C	Apoptosis; Calcium Channel; Reactive Oxygen Species; IGF-1R; Endogenous Metabolite	Apoptosis; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; NF-κB; Tyrosine Kinase/Adaptors
	Urolithin C 属于多酚类，是鞣花酸的肠道微生物代谢产物，具有胰岛素分泌的葡萄糖依赖性激活活性。Urolithin C 是 L 型 Ca2+通道开放剂，可增强 Ca2+的流入。它通过线粒体介导的途径诱导细胞凋亡，并刺激活性氧的形成。
T4S0554	Theaflavine-3,3'-digallate TFBG,theaflavin digallate,3,3’-二没食子酸酯茶黄素	Others	Others
	Theaflavine-3,3'-digallate (theaflavin digallate) 和乳酸一起可以减少单纯疱疹病毒的传播。
T4722	O-Acetyl-L-serine hydrochloride	Others; Endogenous Metabolite	Metabolism; Others
	O-Acetyl-L-serine hydrochloride 是内源性代谢产物的一种。
T13265	Urolithin B 尿石素B,3-羟基-6H-苯并[C]苯并吡喃-6-酮	ERK; NF-κB; Akt; Endogenous Metabolite; JNK; AMPK	Chromatin/Epigenetic; Cytoskeletal Signaling; MAPK; Metabolism; NF-κB; PI3K/Akt/mTOR signaling
	Urolithin B 是一种 ellagitannins 的肠道微生物代谢产物，具有抗炎和抗氧化作用。它也是骨骼肌质量的调节因子，通过减少 IκBα 的磷酸化和降解来抑制 NF-κB 活性，并抑制 JNK、ERK 和 Akt 的磷酸化，并增强 AMPK 的磷酸化。
T5089	5-Aminovaleric acid	Others; Endogenous Metabolite	Metabolism; Others
	5-Aminovaleric acid 被认为是 GABA 的亚甲基同系物，是GABA 的弱激动剂。它是赖氨酸降解产物。它既能够内源性产生，也能够通过赖氨酸的细菌分解代谢产生。

天然产物

Urolithin C

Cat.No: TN7108

Synonym:

Target: Apoptosis, Calcium Channel, Reactive Oxygen Species, IGF-1R, Endogenous Metabolite

Theaflavine-3,3'-digallate

Cat.No: T4S0554

Synonym: TFBG,theaflavin digallate,3,3’-二没食子酸酯茶黄素

Target: Others

O-Acetyl-L-serine hydrochloride

Cat.No: T4722

Synonym:

Target: Others, Endogenous Metabolite

Urolithin B

Cat.No: T13265

Synonym: 尿石素B,3-羟基-6H-苯并[C]苯并吡喃-6-酮

Target: ERK, NF-κB, Akt, Endogenous Metabolite, JNK, AMPK

5-Aminovaleric acid

Cat.No: T5089

Synonym:

Target: Others, Endogenous Metabolite

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPK-01137	FAM3D Protein, Human, Recombinant (hFc) OIT1,EF7,FAM3D	Human	HEK293 Cells
	The physiological homeostasis of gut mucosal barrier is maintained by both genetic and environmental factors and its impairment leads to pathogenesis such as inflammatory bowel disease. A cytokine like molecule, FAM3D (mouse Fam3D), is highly expressed in mouse gastrointestinal tract. Here, we demonstrate that deficiency in Fam3D is associated with impaired integrity of colonic mucosa, increased epithelial hyper-proliferation, reduced anti-microbial peptide production and increased sensitivity t...
TMPH-02239	TMPRSS4 Protein, Human, Recombinant (His & Myc) Channel-activating protease 2,TMPRSS4,Transmembrane protease...	Human	E. coli
	Plasma membrane-anchored serine protease that directly induces processing of pro-uPA/PLAU into the active form through proteolytic activity. Seems to be capable of activating ENaC.; (Microbial infection) In gut epithelial cells, facilitates human coronavirus SARS-CoV-2 infection through, at least, the cleavage of coronavirus spike glycoproteins which activates the glycoprotein for host cell entry. TMPRSS4 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10...

重组蛋白

FAM3D Protein, Human, Recombinant (hFc)

Cat.No: TMPK-01137

Species: Human

Expression System: HEK293 Cells

TMPRSS4 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-02239

Species: Human

Expression System: E. coli

Cat. No.	Product Name	Target	Signaling Pathways
TMIJ-0047	Isobutyric-d6 acid
	Isobutyric-d6 acid 是 Isobutyric acid 的氘代化合物。Isobutyric acid 的 CAS 号为 79-31-2。Isobutyric acid 是一种羧酸或短链脂肪酸，具有特征性的汗味。通过微生物（肠道）代谢产生少量异丁酸。在某些食物或发酵饮料中也可能发现少量。
TMIJ-0053	2-Methylpropionic-d7 acid
	2-Methylpropionic-d7 acid 是 2-Methylpropionic acid 的氘代化合物。2-Methylpropionic acid 的 CAS 号为 79-31-2。Isobutyric acid 是一种羧酸或短链脂肪酸，具有特征性的汗味。通过微生物（肠道）代谢产生少量异丁酸。在某些食物或发酵饮料中也可能发现少量。