|
TMPY-01442
|
DMBT1 Protein, Human, Recombinant (His)
GP340,deleted in malignant brain tumors 1,muclin
|
Human
|
HEK293 Cells
|
|
Deleted in malignant brain tumors 1 protein, also known as glycoprotein 34, surfactant pulmonary-associated D-binding protein, DMBT1 and GP34, is a secreted protein which belongs to theDMBT1 family. DMBT1 contains 2CUB domains, 14SRCR domains and 1ZP domain. It is highly expressed in alveolar and macrophage tissues. In some macrophages, expression is detected on the membrane, and in other macrophages, it is strongly expressed in the phagosome/phagolysosome compartments. Defects in DMBT1 are invo... |
|
TMPY-04483
|
IRAK4 Protein, Human, Recombinant (His)
IPD1,NY-REN-64,REN64,interleukin-1 receptor-associated kinas...
|
Human
|
Baculovirus Insect Cells
|
|
Interleukin-1 receptor-associated kinase 4, also known as Renal carcinoma antigen NY-REN-64, IRAK-4, and IRAK4, is a member of the protein kinase superfamily, TKL Ser/Thr protein kinase family, and Pelle subfamily. IRAK4 contains one death domain and one protein kinase domain. IRAK4 is required for the efficient recruitment of IRAK1 to the IL-1 receptor complex following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. ... |
|
TMPH-02271
|
BTK Protein, Human, Recombinant (His)
BPK,AGMX1,ATK,B-cell progenitor kinase,Tyrosine-protein kina...
|
Human
|
Baculovirus Insect Cells
|
|
Non-receptor tyrosine kinase indispensable for B lymphocyte development, differentiation and signaling. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. After BCR engagement and activation at the plasma membrane, phosphorylates PLCG2 at several sites, igniting the downstream signaling pathway through calcium mobilization, followed by activation of the protein kinase C (PKC) family members. PLCG2 phosphorylation is performed in... |
|
TMPH-03738
|
Endochitinase B Protein, Zea mays, Recombinant (His & Myc)
ChitB,CHIB,Endochitinase B,Seed chitinase B,CTB1
|
Zea mays
|
E. coli
|
|
Defense against chitin-containing fungal pathogens. |
|
TMPH-03297
|
LGALS3BP Protein, Rat, Recombinant (His)
Protein 90K,Mac-2-binding protein,Galectin-3-binding protein...
|
Rat
|
E. coli
|
|
Promotes integrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells. |
|
TMPH-03060
|
NaD1 Protein, Nicotiana alata, Recombinant (His & SUMO)
D1,Flower-specific defensin,NaD1
|
Nicotiana alata
|
E. coli
|
|
Plant defense peptide with antifungal activity against F.oxysporum and B.cinerea. Retards the growth of the Lepidopteran insect pests H.armigera and H.punctigera. |
|
TMPH-00135
|
Endochitinase Protein, Avena sativa, Recombinant (His)
|
Avena sativa
|
E. coli
|
|
This protein functions as a defense against chitin-containing fungal pathogens. Endochitinase Protein, Avena sativa, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 25.7 kDa and the accession number is P86181. |
|
TMPH-01551
|
IFNLR1 Protein, Human, Recombinant (His & SUMO)
Cytokine receptor class-II member 12,Likely interleukin or c...
|
Human
|
E. coli
|
|
The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state. Determines the cell type specificity of the lambda interferon action. Shows a more restricted pattern of expression in the epithelial tissues thereby limiting responses to lambda interferons primar... |
|
TMPH-01600
|
Lactoperoxidase/LPO Protein, Human, Recombinant (His & Myc)
LPO,Salivary peroxidase,Lactoperoxidase
|
Human
|
HEK293 Cells
|
|
Antimicrobial agent which utilizes hydrogen peroxide and thiocyanate (SCN) to generate the antimicrobial substance hypothiocyanous acid (HOSCN). May contribute to airway host defense against infection. |
|
TMPJ-00476
|
BMPG Protein, Human, Recombinant (His)
Bone Marrow Proteoglycan,PRG2,Proteoglycan 2,Eosinophil Gran...
|
Human
|
HEK293 Cells
|
|
Bone Marrow Proteoglycan (BMPG) is a secreted protein that contains one C-type lectin domain. BMPG is the predominant constituent of the crystalline core of the eosinophil granule. BMPG is highly expressed in placenta and pregnancy serum. BMPG may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin. BMPG induces non-cytolytic histamine release from human basophils. In addition, BMPG also participated in antiparasitic defense mechanisms and immune hypersensitivity re... |
|
TMPH-01362
|
LGALS3BP Protein, Human, Recombinant (His)
LGALS3BP,Lectin galactoside-binding soluble 3-binding protei...
|
Human
|
E. coli
|
|
Promotes integrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells. LGALS3BP Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 67.4 kDa and the accession number is Q08380. |
|
TMPH-03151
|
Gingipain R1 Protein, Porphyromonas gingivalis, Recombinant (His)
Gingipain 1,Gingipain R1,RGP-1,Arg-gingipain,rgpA
|
Porphyromonas gingivalis
|
P. pastoris (Yeast)
|
|
Thiol protease. Acts synergistically with RgpB to catalyze the maturation of fimbrial subunits, such as FimA. Its proteolytic activity is a major factor in both periodontal tissue destruction and in evasion of host defense mechanisms (Probable). Gingipain R1 Protein, Porphyromonas gingivalis, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 56.0 kDa and the accession number is P28784. |
|
TMPH-00824
|
Oxalate oxidase 1 Protein, Hordeum vulgare, Recombinant (His & Myc)
Oxalate oxidase 1,Germin
|
Hordeum vulgare
|
E. coli
|
|
Releases hydrogen peroxide in the apoplast which may be important for cross-linking reactions in the cell wall biochemistry. May play an important role in several aspects of plant growth and defense mechanisms. Oxalate oxidase 1 Protein, Hordeum vulgare, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 28.2 kDa and the accession number is P45850. |
|
TMPK-01279
|
GUCY2C Protein, Cynomolgus, Recombinant (aa 24-430, His)
GUC2CEC 4.6.1.2,GCC,Guanylyl cyclase C,STA receptor,MUCIL,GU...
|
Cynomolgus
|
HEK293 Cells
|
|
Guanylyl cyclase C (GUCY2C) has canonical centrality in defense of key intestinal homeostatic mechanisms, encompassing fluid and electrolyte balance, epithelial dynamics, antitumorigenesis, and intestinal barrier function. GUCY2C may represent a new target for anti-obesity pharmacotherapy. GUCY2C Protein, Cynomolgus, Recombinant (aa 24-430, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 47.2 kDa and the accession number is XP_005570270.1. |
|
TMPK-00856
|
GUCY2C Protein, Human, Recombinant (His & Avi)
GCC,STAR,STA receptor,Guanylyl cyclase C,EC 4.6.1,GUC2C,MUCI...
|
Human
|
HEK293 Cells
|
|
Guanylyl cyclase C (GUCY2C) has canonical centrality in defense of key intestinal homeostatic mechanisms, encompassing fluid and electrolyte balance, epithelial dynamics, antitumorigenesis, and intestinal barrier function. GUCY2C may represent a new target for anti-obesity pharmacotherapy. GUCY2C Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 48.8 kDa and the accession number is P25092-1. |
|
TMPH-03145
|
Thanatin Protein, Podisus maculiventris, Recombinant (His & KSI)
Thanatin
|
Podisus maculiventris
|
E. coli
|
|
Insect defense peptide with a broad spectrum of activity against Gram-positive and Gram-negative bacteria and fungi. No activity against S.aureus. Stops respiration in bacteria but does not permeabilize their inner membranes. Thanatin Protein, Podisus maculiventris, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight is 17.8 kDa and the accession number is P55788. |
|
TMPH-00284
|
MBP-C Protein, Bovine, Recombinant (His)
Mannose-binding protein C,MBL,Mannan-binding protein
|
Bovine
|
Baculovirus Insect Cells
|
|
Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. MBP-C Protein, Bovine, Recombinant (His) is expressed in Baculovirus insect cells with N-10xHis tag. The predicted molecular weight is 26.9 kDa and the accession... |
|
TMPK-01040
|
NKG2C/CD159c Protein, Cynomolgus, Recombinant (His)
NKG2C,NK cell receptor C,CD159c,KLRC2
|
Cynomolgus
|
HEK293 Cells
|
|
As a first line of defense, natural killer (NK) cells play a crucial role in the fight against infections. The presented study is the first of its kind that ascribes CD56dimCD16 NKG2C-expressing NK cells a crucial role in biasing adaptive immune responses upon influenza vaccination and suggests NKG2C as a potential biomarker in predicting pandemic influenza vaccine responsiveness. |
|
TMPH-00721
|
YgiS Protein, E. coli, Recombinant (His & SUMO)
Probable deoxycholate-binding periplasmic protein YgiS,ygiS
|
E. coli
|
E. coli
|
|
Probably part of a deoxycholate transport system. Its expression in the presence of deoxycholate in a ygiS deletion mutant increases intracellular deoxycholate levels and decreases cell growth; higher expression in the presence of deoxycholate inhibits cell growth completely. Bile acid detergents such as deoxycholate are important for host defense against bacterial growth in the gall bladder and duodenum. |
|
TMPK-00990
|
GUCY2C Protein, Mouse, Recombinant (His & Avi)
GC-C,STAR,DIAR6,GCC,GUC2CEC 4.6.1.2,STA receptor,MUCIL,GUCY2...
|
Mouse
|
HEK293 Cells
|
|
Guanylyl cyclase C (GUCY2C) has canonical centrality in defense of key intestinal homeostatic mechanisms, encompassing fluid and electrolyte balance, epithelial dynamics, antitumorigenesis, and intestinal barrier function. GUCY2C may represent a new target for anti-obesity pharmacotherapy. GUCY2C Protein, Mouse, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 50.01 kDa and the accession number is Q3UWA6-1. |
|
TMPH-00346
|
Limulus clotting factor C Protein, Carcinoscorpius rotundicauda, Recombinant (His)
Limulus clotting factor C
|
Carcinoscorpius rotundicauda
|
E. coli
|
|
This enzyme is closely associated with an endotoxin-sensitive hemolymph coagulation system which may play important roles in both hemostasis and host defense mechanisms. Its active form catalyzes the activation of factor B. Limulus clotting factor C Protein, Carcinoscorpius rotundicauda, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 42.2 kDa and the accession number is Q26422. |
|
TMPH-01011
|
PRG2 Protein, Human, Recombinant (GST & His)
Bone marrow proteoglycan,PRG2,Proteoglycan 2
|
Human
|
E. coli
|
|
Cytotoxin and helminthotoxin. Also induces non-cytolytic histamine release from human basophils. Involved in antiparasitic defense mechanisms and immune hypersensitivity reactions. The proform acts as a proteinase inhibitor, reducing the activity of PAPPA. PRG2 Protein, Human, Recombinant (GST & His) is expressed in E. coli expression system with N-6xHis-GST tag. The predicted molecular weight is 41.2 kDa and the accession number is P13727. |
|
TMPJ-00720
|
TXNDC12 Protein, Human, Recombinant (His)
TLP19,ERp19,Thioredoxin Domain-Containing Protein 12,hTLP19,...
|
Human
|
HEK293 Cells
|
|
Thioredoxin Domain-Containing Protein 12 belongs to the thioredoxin superfamily. In this family, proteins possess a thioredoxin fold with a consensus active-site sequence (CxxC) and have roles in redox regulation, defense against oxidative stress, refolding of disulfide-containing proteins, and regulation of transcription factors. TXNDC12 is widely expressed in many tissues and contains one thioredoxin domain. |
|
TMPY-00587
|
GABARAP Protein, Human, Recombinant (His & MBP)
GABARAP-a,GABA(A) receptor-associated protein,ATG8A,MM46
|
Human
|
E. coli
|
|
The Atg8/LC3/GABARAP family of proteins, a group that has structural homology with ubiquitin, connects with a large set of binding partners to function in macroautophagy (hereafter autophagy). GABARAP in tumorigenesis in vivo by delaying cell death and its associated immune-related response. GABARAPs are uniquely required for antimicrobial host defense through cytosolic distribution of interferon-inducible GTPases. GABARAPs as the first known direct interaction partners of Nef that are essential... |
|
TMPY-02125
|
CCL6 Protein, Mouse, Recombinant (His)
Scya6,MRP-1,c10,RP23-320E6.4,chemokine (C-C motif) ligand 6
|
Mouse
|
HEK293 Cells
|
|
Chemokine (C-C motif) ligand 6 (CCL6), also known as C-C chemokine C10 has only been identified in rodents, which is a small cytokine belonging to the CC chemokine family, beta-chemokine subfamily. C-C chemokine C10 is involved in the chronic stages of host defense reactions. C10 chemokine rapidly promotes disease resolution in the cecal ligation and puncture (CLP) model through its direct effects on the cellular events critically involved in host defense during septic peritonitis. CCL6 appears ... |
|
TMPH-01397
|
LANCL1 Protein, Human, Recombinant (His & Myc)
LANCL1,40 kDa erythrocyte membrane protein,Glutathione S-tra...
|
Human
|
E. coli
|
|
Functions as glutathione transferase. Catalyzes conjugation of the glutathione (GSH) to artificial substrates 1-chloro-2,4-dinitrobenzene (CDNB) and p-nitrophenyl acetate. Mitigates neuronal oxidative stress during normal postnatal development and in response to oxidative stresses probably through GSH antioxidant defense mechanism. May play a role in EPS8 signaling. Binds glutathione. LANCL1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc... |
|
TMPH-02824
|
Perforin-1/PRF1 Protein, Mouse, Recombinant (His)
Lymphocyte pore-forming protein,Cytolysin,Perforin-1,Prf1
|
Mouse
|
E. coli
|
|
Plays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells. Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores. Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes. |
|
TMPJ-01203
|
HATL5 Protein, Human, Recombinant (His)
HATL5,Transmembrane Protease Serine 11B,Airway Trypsin-Like ...
|
Human
|
HEK293 Cells
|
|
Transmembrane Protease Serine 11B (TMPRSS11B) is a single-pass type II membrane protein member of the peptidase S1 family. TMPRSS11B contains one peptidase S1 domain and one SEA domain. TMPRSS11B is a serine protease that may play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions. |
|
TMPK-01388
|
GUCY2C Protein, Canine, Recombinant (aa 21-430, His)
GC-C,GUCY2C,STAR,EC 4.6.1,STA receptor,GCC,MUCIL,Guanylyl cy...
|
Canine
|
HEK293 Cells
|
|
Guanylyl cyclase C (GUCY2C) has canonical centrality in defense of key intestinal homeostatic mechanisms, encompassing fluid and electrolyte balance, epithelial dynamics, antitumorigenesis, and intestinal barrier function. GUCY2C may represent a new target for anti-obesity pharmacotherapy. GUCY2C Protein, Canine, Recombinant (aa 21-430, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 47.6 kDa and the accession number is F1PAG3. |
|
TMPH-03153
|
Gingipain R2 Protein, Porphyromonas gingivalis, Recombinant (His)
rgpB,Gingipain 2,RGP-2,Arg-gingipain,Gingipain R2
|
Porphyromonas gingivalis
|
E. coli
|
|
Thiol protease. Acts synergistically with RgpA to catalyze the maturation of fimbrial subunits, such as FimA. Its proteolytic activity is a major factor in both periodontal tissue destruction and in evasion of host defense mechanisms. Gingipain R2 Protein, Porphyromonas gingivalis, Recombinant (His) is expressed in E. coli expression system with C-10xHis tag. The predicted molecular weight is 57.1 kDa and the accession number is P95493. |
|
TMPH-03327
|
MBL2 Protein, Rat, Recombinant (His)
Mannan-binding protein,Ra-reactive factor polysaccharide-bin...
|
Rat
|
E. coli
|
|
Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. MBL2 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 30.0 kDa and the accession num... |
|
TMPK-00859
|
NKG2C/CD159c Protein, Human, Recombinant (His & Avi), Biotinylated
NK cell receptor C,KLRC2,CD159c,NKG2C
|
Human
|
HEK293 Cells
|
|
As a first line of defense, natural killer (NK) cells play a crucial role in the fight against infections.The presented study is the first of its kind that ascribes CD56dimCD16 NKG2C-expressing NK cells a crucial role in biasing adaptive immune responses upon influenza vaccination and suggests NKG2C as a potential biomarker in predicting pandemic influenza vaccine responsiveness. NKG2C/CD159c Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-His-... |
|
TMPH-03529
|
Chemotaxis inhibitory Protein, S. aureus (strain MRSA252), Recombinant (His)
CHIPS,Chemotaxis inhibitory protein,chp
|
Staphylococcus aureus
|
P. pastoris (Yeast)
|
|
Involved in countering the first line of host defense mechanisms. Specifically inhibits the response of human neutrophils and monocytes to complement anaphylatoxin C5a and formylated peptides, like N-formyl-methionyl-leucyl-phenylalanine (fMLP). Acts by binding directly to the C5a receptor (C5aR) and formylated peptide receptor (FPR), thereby blocking the C5a- and fMLP-induced calcium responses. Prevents phagocytosis of the bacterium. Chemotaxis inhibitory Protein, S. aureus (strain MRSA252), Re... |
|
TMPK-00991
|
GUCY2C Protein, Mouse, Recombinant (His & Avi), Biotinylated
EC 4.6.1,Guanylyl cyclase C,MUCIL,GUC2CEC 4.6.1.2,GUC2C,STA ...
|
Mouse
|
HEK293 Cells
|
|
Guanylyl cyclase C (GUCY2C) has canonical centrality in defense of key intestinal homeostatic mechanisms, encompassing fluid and electrolyte balance, epithelial dynamics, antitumorigenesis, and intestinal barrier function. GUCY2C may represent a new target for anti-obesity pharmacotherapy. GUCY2C Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 50.01 kDa and the accession number is Q3UWA6-1. |
|
TMPH-03618
|
Clotting factor C Protein, Tachypleus tridentatus, Recombinant (His & Myc)
FC,Limulus factor C,Clotting factor C
|
Tachypleus tridentatus
|
E. coli
|
|
This enzyme is closely associated with an endotoxin-sensitive hemolymph coagulation system which may play important roles in both hemostasis and host defense mechanisms. Its active form catalyzes the activation of clotting factor B. Clotting factor C Protein, Tachypleus tridentatus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 33.8 kDa and the accession number is P28175. |
|
TMPH-03152
|
Gingipain R1 Protein, Porphyromonas gingivalis, Recombinant (B2M & His)
RGP-1,Arg-gingipain,Gingipain R1,Gingipain 1,rgpA
|
Porphyromonas gingivalis
|
E. coli
|
|
Thiol protease. Acts synergistically with RgpB to catalyze the maturation of fimbrial subunits, such as FimA. Its proteolytic activity is a major factor in both periodontal tissue destruction and in evasion of host defense mechanisms (Probable). Gingipain R1 Protein, Porphyromonas gingivalis, Recombinant (B2M & His) is expressed in E. coli expression system with N-6xHis-B2M tag. The predicted molecular weight is 68.0 kDa and the accession number is P28784. |
|
TMPJ-00872
|
MGMT Protein, Human, Recombinant (His)
MGMT,6-O-methylguanine-DNAmethyltransferase,O-6-methylguanin...
|
Human
|
E. coli
|
|
MGMT belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. MGMT involved in the cellular defense against the biological effects of O6-methylguanine in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. MGMT catalyzes the chemical reaction: DNA (containing 6-O-methylguanine) and proteinL-cysteine into DNA (without 6-O-methylguanine) and protein S-met... |
|
TMPH-01607
|
LCE3A Protein, Human, Recombinant (His)
Late envelope protein 13,LCE3A,Late cornified envelope prote...
|
Human
|
E. coli
|
|
A structural component of the cornified envelope of the stratum corneum involved in innate cutaneous host defense (Probable). Possesses defensin-like antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative bacteria, both aerobic and anaerobic species. Upon inflammation, may regulate skin barrier repair by shaping cutaneous microbiota composition and immune response to bacterial antigens. LCE3A Protein, Human, Recombinant (His) is expressed in E. coli expression system ... |
|
TMPH-03097
|
Beta-elicitin cryptogein Protein, Phytophthora cryptogea, Recombinant (His & Myc)
Beta-elicitin cryptogein,CRY
|
Phytophthora cryptogea
|
E. coli
|
|
Induces local and distal defense responses (incompatible hypersensitive reaction) in plants from the solanaceae and cruciferae families. Elicits leaf necrosis and causes the accumulation of pathogenesis-related proteins. Might interact with the lipidic molecules of the plasma membrane. Beta-elicitin cryptogein Protein, Phytophthora cryptogea, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 17.3 kDa and the accession... |
|
TMPK-01199
|
NKG2C/CD159c Protein, Mouse, Recombinant (hFc)
NKG2C,KLRC2,CD159c,NK cell receptor C
|
Mouse
|
HEK293 Cells
|
|
As a first line of defense, natural killer (NK) cells play a crucial role in the fight against infections.The presented study is the first of its kind that ascribes CD56dimCD16 NKG2C-expressing NK cells a crucial role in biasing adaptive immune responses upon influenza vaccination and suggests NKG2C as a potential biomarker in predicting pandemic influenza vaccine responsiveness. NKG2C/CD159c Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted m... |
|
TMPK-01190
|
GPVI Protein, Human, Recombinant (His)
Glycoprotein 6,Gp6,MGC138168,GPVI
|
Human
|
HEK293 Cells
|
|
Although platelets are best known for their role in hemostasis, they are also crucial in development, host defense, inflammation, and tissue repair. Many of these roles are regulated by the immune-like receptors glycoprotein VI (GPVI) and C-type lectin receptor 2 (CLEC-2), which signal through an immunoreceptor tyrosine-based activation motif (ITAM). GPVI is activated by collagen in the subendothelial matrix, by fibrin and fibrinogen in the thrombus, and by a remarkable number of other ligands. ... |
|
TMPH-03528
|
Chemotaxis inhibitory Protein, S. aureus (strain NCTC 8325/PS47), Recombinant (His & Myc)
chp,Chemotaxis inhibitory protein,CHIPS
|
Staphylococcus aureus
|
E. coli
|
|
Involved in countering the first line of host defense mechanisms. Specifically inhibits the response of human neutrophils and monocytes to complement anaphylatoxin C5a and formylated peptides, like N-formyl-methionyl-leucyl-phenylalanine (fMLP). Acts by binding directly to the C5a receptor (C5aR) and formylated peptide receptor (FPR), thereby blocking the C5a- and fMLP-induced calcium responses. Prevents phagocytosis of the bacterium. Chemotaxis inhibitory Protein, S. aureus (strain NCTC 8325/PS... |
|
TMPJ-00527
|
SP-D Protein, Human, Recombinant (His)
Lung Surfactant Protein D,SFTP4,COLEC7,SFTPD,PSP-D,SP-D,Pulm...
|
Human
|
HEK293 Cells
|
|
Surfactant Pulmonary-Associated Protein D (SP-D) is a 43 kDa member of the collectin family of innate immune modulators. Its principal components consist of a collagen-like region and a C-terminal carbohydrate recognition domain (CRD), a structure that places it in a subset of pattern recognition proteins termed defense collagens. SP-D is constitutively secreted by alveolar lining cells and epithelium associated with tubular structures and induced in cardiac smooth muscle and endothelial cells. ... |
|
TMPK-00858
|
NKG2C/CD159c Protein, Human, Recombinant (His & Avi)
NK cell receptor C,KLRC2,CD159c,NKG2C
|
Human
|
HEK293 Cells
|
|
As a first line of defense, natural killer (NK) cells play a crucial role in the fight against infections.The presented study is the first of its kind that ascribes CD56dimCD16 NKG2C-expressing NK cells a crucial role in biasing adaptive immune responses upon influenza vaccination and suggests NKG2C as a potential biomarker in predicting pandemic influenza vaccine responsiveness. NKG2C/CD159c Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with N-His-Avi tag. The p... |
|
TMPH-03578
|
SCIN Protein, S. aureus, Recombinant (His & Myc)
scn,Staphylococcal complement inhibitor
|
Staphylococcus aureus
|
E. coli
|
|
Involved in countering the first line of host defense mechanisms. Efficiently inhibits opsonization, phagocytosis and killing of S.aureus by human neutrophils. Acts by binding and stabilizing human C3 convertases (C4b2a and C3bBb), leading to their inactivation. The convertases are no longer able to cleave complement C3, therefore preventing further C3b deposition on the bacterial surface and phagocytosis of the bacterium. Also prevents C5a-induced neutrophil responses. SCIN Protein, S. aureus, ... |
|
TMPK-01302
|
GPVI Protein, Cynomolgus, Recombinant (His)
Glycoprotein 6,MGC138168,GPVI,Gp6
|
Cynomolgus
|
HEK293 Cells
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Although platelets are best known for their role in hemostasis, they are also crucial in development, host defense, inflammation, and tissue repair. Many of these roles are regulated by the immune-like receptors glycoprotein VI (GPVI) and C-type lectin receptor 2 (CLEC-2), which signal through an immunoreceptor tyrosine-based activation motif (ITAM). GPVI is activated by collagen in the subendothelial matrix, by fibrin and fibrinogen in the thrombus, and by a remarkable number of other ligands. ... |
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TMPJ-01241
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DTD1 Protein, Human, Recombinant (His)
DUE-B,D-tyrosyl-tRNA(Tyr) deacylase 1,DNA-unwinding element-...
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Human
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HEK293 Cells
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D-tyrosyl-tRNA(Tyr) deacylase 1(DTD1) belongs to the DTD family, and expressed in many adult and fetal tissues such as testis, ovary, spleen in adult and fetal brain. It is a nucleus and cytoplasm located protein, and is preferentially phosphorylated in cells arrested early in S phase. DTD1 is an ATPase involved in DNA replication, it may facilitate loading of CDC45 onto pre-replication complexes. The protein may hydrolyze D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr), a possible defens... |
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TMPJ-00149
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Complement Factor D/CFD Protein, Mouse, Recombinant (His)
C3 convertase activator,28 kDa adipocyte protein,Cfd,Adipsin...
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Mouse
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HEK293 Cells
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Complement factor D, also known as adipsin, is a member of the chymotrypsin family of serine proteases, which plays an essential role in host defense as the rate-limiting enzyme in the alternative pathway of complement activation. Complement factor D activates a convertase (C3bBb) responsible for cleavage of the complement protein C3, which leads to the activation of terminal complement component C5-9 to form the membrane attack complex on microbial or cellular surfaces. It also functions in the... |
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TMPH-01080
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Ceruloplasmin Protein, Human, Recombinant (His & Myc)
CP,Ceruloplasmin,Ferroxidase ceruloplasmin,Cuproxidase cerul...
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Human
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E. coli
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Ceruloplasmin is a blue, copper-binding (6-7 atoms per molecule) glycoprotein. It has ferroxidase activity oxidizing Fe(2+) to Fe(3+) without releasing radical oxygen species. It is involved in iron transport across the cell membrane. Provides Cu(2+) ions for the ascorbate-mediated deaminase degradation of the heparan sulfate chains of GPC1. May also play a role in fetal lung development or pulmonary antioxidant defense. Ceruloplasmin Protein, Human, Recombinant (His & Myc) is expressed in E. co... |
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TMPJ-00200
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EpCAM/TROP1 Protein, Mouse, Recombinant (hFc)
17-1A,323/A3,TROP1,EGP314,ACSTD1,CD326,EGP-2,MOC31,EGP40,TAC...
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Mouse
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HEK293 Cells
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Epithelial Cellular Adhesion Molecule (Ep-CAM), also known as EGP314, mEGP314, Protein 289A, Tumor-associated calcium signal transducer 1, CD326, belongs to the EPCAM family. Its’ monomer subunit structure interacts with phosphorylated CLDN7. Ep-CAM may act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection... |
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