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Search Results for " bifunctional "

Targets Recommended: Estrogen Receptor/ERR PROTACs

55

抑制剂 & 化合物

17

重组蛋白

1

同位素标记化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T39710	ARV-471 Vepdegestrant	Estrogen Receptor/ERR; PROTACs	Endocrinology/Hormones; PROTAC
	ARV-471 (Vepdegestrant) 是一种高效的，口服有效的基于 Cereblon 配体的雌激素受体降解剂 PROTAC 。ARV-471 常用于研究乳腺癌。
T6798	Tretazicar 5-Aziridino-2,4-dinitrobenzamide,CB1954,NSC 115829	DNA Alkylator/Crosslinker; DNA Alkylation	DNA Damage/DNA Repair
	Tretazicar (NSC-115829) 是一种抗肿瘤前药，由 NAD(P)H 醌氧化还原酶 2 激活。它在酶促活化后生成细胞毒性双功能烷基剂，可以形成 DNA-DNA 链间交联。
T7750	N-[3,5-bis(trifluoroMethyl)phenyl]-N'-[(9R)-6'-Methoxycinchonan-9-yl]- Thiourea N-[3,5-双(三氟甲基)苯基]-N′-[(9R)-6′-甲氧基-9-金鸡宁]硫脲	Others	Others
	N-[3,5-bis(trifluoroMethyl)phenyl]-N'-[(9R)-6'-Methoxycinchonan-9-yl]- Thiourea 是金鸡纳生物碱衍生的双功能催化剂。
T17159	Treosulfan NSC 39069,曲奥舒凡,Treosulphan	DNA Alkylator/Crosslinker; DNA Alkylation	DNA Damage/DNA Repair
	Treosulfan (Treosulphan) 是一种双功能的烷化剂，对卵巢癌及其他的实体瘤都有抑制效果。
T15178	dTRIM24	Others; PROTACs	Others; PROTAC
	dTRIM24 是一种基于 PROTAC 技术的选择性双功能 TRIM24 降解剂，由von Hippel-Lindau 和TRIM24 两者配体构成。
T18728	Sulfo-SMCC sodium	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	Sulfo-SMCC sodium 是一种异双功能、不可裂解的 ADC 交联剂，带有 N-羟基琥珀酰亚胺酯和马来酰亚胺基团，分别与伯胺和巯基反应。
T4382	Proguanil hydrochloride Paludrine hydrochloride,盐酸氯胍,Chlorguanide hydrochloride,Chloroquanil	Others; Dehydrogenase; DNA/RNA Synthesis; Antifolate; Parasite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology; Others
	Proguanil hydrochloride (Chloroquanil) 是一种双胍类抗疟疾剂，在体内代谢形成环胍。它还是一种二氢叶酸还原酶抑制剂。
T26803	Bibw 22 Bibw22,Bibw-22	Others	Others
	Bibw 22 is a bifunctional modulator of P-glycoprotein and nucleoside transport.
T19168	9-Azido-Neu5DAz	Others	Others
	9-Azido-Neu5DAz is a non-natural bifunctional carbohydrates as imaging agent.
T14267	Aminooxy-PEG3-C2-NH-Boc	Others	Others
	Aminooxy-PEG3-C2-NH-Boc is a PEGylated PROTAC linker utilized in the synthesis of PROTACs, an emerging class of bifunctional molecules for targeted protein degradation[1].
T19207	BFCAs-1	Others	Others
	BFCAs-1 is a polyamine polycarboxylic bifunctional chelating agent (BFCAs) with a broad range of applications in biology, chemistry, medicine and diagnostic imaging.
T16181	N-(Azido-PEG2)-N-Boc-PEG4-Boc	Others	Others
	N-(Azido-PEG2)-N-Boc-PEG4-Boc is a PEG-based bifunctional linker employed for the synthesis of PROTACs.
T28846	SR16835 AT-202,AT202,SR 16835,SR-16835	Others	Others
	SR16835 is a NOP receptor agonist, with low-affinity bifunctional activity at the μ opioid receptor.
T18744	t-Boc-Aminooxy-PEG7-bromide	Others	Others
	t-Boc-Aminooxy-PEG7-bromide is a polyethylene glycol (PEG)-based bifunctional linker utilized in the synthesis of proteolysis targeting chimeras (PROTACs)[1].
T70925	GS-5759	Others	Others
	GS-5759 is a bifunctional ß2-Adrenoceptor Agonist and Phosphodiesterase 4 Inhibitor for Chronic Obstructive Pulmonary Disease with a Unique Mode of Action.
T68272	Batefenterol Succinate	Others	Others
	Batefenterol Succinate is a first-in-class inhaled bifunctional bronchodilator possessing muscarinic receptor antagonist and β2-adrenoceptor agonist properties.
T25140	BCH 2763 BCH2763,BCH-2763	Others	Others
	BCH 2763 is an effective, selective bifunctional thrombin inhibitor that blocks both the anion binding exosite and the active catalytic site.
T41024	FmocNH-PEG4-t-butyl acetate FmocNH-PEG4-t-butyl acetate	Others	Others
	FmocNH-PEG4-t-butyl acetate is a polyethylene glycol (PEG)-derived PROTAC linker employed for the synthesis of PROTACs, bifunctional molecules designed to degrade target proteins.
T40648	NOTA	Others	Others
	NOTA, a bifunctional chelate, serves as a foundation for PET imaging tool construction, probe design, and signal amplification through the multivalent effect.
T34173	p-SCN-Bn-HOPO	Others	Others
	p-SCN-Bn-HOPO is an excellent bifunctional chelating agent for (89)Zr ImmunoPET, with low background, good tumor-organ contrast, and importantly, very low bone uptake for BT474 breast cancer imaging.
T81433	p-NH2-CHX-A"-DTPA	Others	Others
	p-NH2-CHX-A"-DTPA 是双功能螯合剂。
T14449	Azido-PEG4-hydrazide-Boc	Others	Others
	Azido-PEG4-hydrazide-Boc is a polyethylene glycol (PEG)-based bifunctional linker compound used in the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].
T16234	N-Mal-N-bis(PEG4-NHS ester)	Others	Others
	N-Mal-N-bis(PEG4-NHS ester) is a polyethylene glycol (PEG)-based bifunctional linker utilized for synthesizing Proteolysis Targeting Chimeras (PROTACs)[1].
T17469	Azide-PEG3-Sulfone-PEG3-azide	Others	Others
	Azide-PEG3-Sulfone-PEG3-azide is a polyethylene glycol (PEG)-based bifunctional molecule, specifically designed as a PROTAC linker for the synthesis of PROTACs[1].
T18080	m-PEG-acrylate (MW 30000)	Others	Others
	m-PEG-acrylate (MW 30000) is a polyethylene glycol (PEG)-based bifunctional linker commonly employed in the chemical synthesis of proteolysis targeting chimeras (PROTACs)[1].
T81384	PROTAC BRD9 Degrader-3	PROTACs	PROTAC
	PROTACBRD9 Degrader-3为BRD9靶向的双功能降解剂，用于癌症研究。
T14163	Ald-Ph-amido-C2-PEG3-NH-Boc	Others	Others
	Ald-Ph-amido-C2-PEG3-NH-Boc is a polyethylene glycol (PEG)-based bifunctional linker utilized for the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].
T18413	N-Desthiobiotin-N-bis(PEG4-t-butyl ester)	Others	Others
	N-Desthiobiotin-N-bis(PEG4-t-butyl ester) is a PEG-based linker compound employed for the synthesis of PROTACs, which are bifunctional molecules designed for targeted protein degradation[1].
T18834	Thiol-PEG-CH2COOH (MW 5000)	Others	Others
	Thiol-PEG-CH2COOH (MW 5000) is a Polyethylene glycol (PEG) derived link molecule, commonly utilized in the construction of PROTACs, which are bifunctional compounds designed for targeted protein degradation [1].
T17962	Fmoc-N-PEG36-acid	Others	Others
	Fmoc-N-amido-PEG36-acid is a polyethylene glycol (PEG)-based linker utilized in PROTAC synthesis. It has been designed specifically for constructing PROTACs, which are bifunctional molecules capable of recruiting target proteins to an E3 ubiquitin ligase for degradation[1].
T81385	PROTAC BRD9 Degrader-2	PROTACs	PROTAC
	PROTACBRD9 Degrader-2是针对癌症研究的BRD9双功能性降解剂。
T31584	DST Crosslinker DST Cross linker,DST Cross-linker	Others	Others
	DST crosslinker(disuccinimide tartarate) is an isotype bifunctional, cleavable crosslinker (cleavable by an oxidizer) for applications that require crosslinking cleavability and that do not interfere with protein disulfide bonds with reducing agents.
T77936	PROTAC BRD9 Degrader-4	PROTACs	PROTAC
	PROTACBRD9 Degrader-4 是一种针对BRD9的双功能降解剂，用于癌症研究。
T82537	D-MoDE-A (1)	LYTACs	PROTAC
	D-MoDE-A（1）是一种双功能小分子，它通过ASGPR（去唾液酸糖蛋白受体）介导外源蛋白的降解。
T77155	Dalutrafusp alfa
	Dalutrafusp alfa (AGEN-1423; GS-1423) 为针对CD73与TGF-β的特异性双功能抗体，涉及免疫抑制路径。
T11938L	Macropa-NH2	Others	Others
	Macropa-NH2 是 macropa 双功能类似物，是一种常与抗体偶联的载体分子，常作为螯合剂使用，参与癌症研究。
T26049	RB 6145 RB6145,RB-6145	Others	Others
	RB 6145是一种双功能硝基咪唑，低氧细胞放射增敏剂RSU 1069的前药，它的毒性较RSU 1069降低。它具有缺氧细胞优先细胞毒性和抗肿瘤治疗活性。
T81779	M-MoDE-A (2)	LYTACs	PROTAC
	M-MoDE-A (2)为双功能小分子，其作用机理包括促进通过ASGPR (去唾液酸糖蛋白受体) 介导的细胞外蛋白质降解。
T69149	L2-b	Others	Others
	L2-b is a bifunctional Aβ-interacting, metal-chelating molecule that modulates ROS production in, and improves survival of neuroblastoma cells incubated in the presence of Aβ along with Copper or Zinc. In cell-free aggregation studies, L2-b inhibits metal-induced Aβ aggregation, and also promotes the dissociation of Ab aggregates in homogenates of human AD brain samples.
T31588	Dynasylan 1161 Y 9138	Others	Others
	Dynasylan 1161 是一种双官能有机硅烷，可以与合适的聚合物反应。在水存在时，Dynasylan 1161可与各种无机基材结合。
T32026	GYKI-13324 GYKI 13324,GYKI13324	Others	Others
	GYKI-13324 is bifunctional nitrosoureido derivative and alkylating agent. GYKI-13324 was studied on human colorectal tumor xenograft lines. Given orally in single or multiple daily doses, GYKI-13324 produced long-term or total regression of adenomatous, b
T28464	p-SCN-Bn-TCMC HCl p-SCN-Bn-TCMC	Others	Others
	p-SCN-Bn-TCMC is a bifunctional chelator, it contains a powerful chelator TCMC and reactive tioisocyante linker. TCMC is a powerful chelator with capability to strongly bind radio-isotopic heavy metal ion, which are widely used for radio-diagnostic/imagin
T82560	di-Ellipticine-RIBOTAC	PROTACs	PROTAC
	Di-Ellipticine-RIBOTAC是一款双功能小分子，在体外和体内肌萎缩侧索硬化（ALS）模型中能够减少c9ALS/FTD r(G4C2)的重复扩增。
T68942	Caricotamide	Others	Others
	Caricotamide is a synthetic co-substrate that activates the human endogenous enzyme NRH:quinone oxidoreductase 2 (NQO2) with potential chemoadjuvant activity. When caricotamide is administered simultaneously with the prodrug tretazicar, NQO2 converts tretazicar to the bifunctional alkylating agent dinitrobenzamide, which is capable of forming a high degree of DNA interstrand cross-links, resulting in the inhibition of DNA replication and the induction of apoptosis. NQO2 has been found to be over...
T82866	Biotin-PEG-Biotin (MW 20000)
	Biotin-PEG-azide (MW 2000) 为含有生物素标记的聚乙二醇 (PEG) 衍生物。该生物素（Biotin）作为酶辅因子，在蛋白质标记应用中具有重要作用，而PEG是低毒性且具亲水性的水溶性聚合物。
T81035	TAT-NSF222 Fusion Peptide
	TAT-NSF222 Fusion Peptide为包含TAT和NSF两个结构域的融合多肽，TAT负责通过巨胞饮促进细胞摄取，而NSF结构域则抑制N-乙基马来酰亚胺敏感因子(NSF)活性。该融合多肽是exocytosis的抑制剂。
T80588	Bintrafusp alfa M7824,MSB0011359C
	Bintrafusp alfa (M 7824) 是高端双功能融合蛋白，融合了转化生长因子β受体II (TGF-βRII) 的细胞外域与人源IgG1单克隆抗体 (mAb) 致程序性细胞死亡配体阻断功能。该化合物主要用于癌症研究领域。
T79618	M3/PDE4 modulator-1	Others	Others
	M3/PDE4 modulator-1 (10f) 为多功能化合物，具备M3mAChR拮抗和PDE4抑制作用。于OVA大鼠模型中，M3/PDE4 modulator-1 (10-1000 nM/kg；iv) 能降低半胱氨酸嗜酸性粒细胞内流。
T81675	NICE-01 AP1867-PEG2-JQ1,AP-PEG2-JQ1
	NICE-01 (AP1867-PEG2-JQ1; AP-PEG2-JQ1)是一款具有双功能的化合物，它通过特异性结合到细胞内特定亚细胞区室中的蛋白质，并以BRD4蛋白的核定位含溴结构域作为诱导，实现将胞浆中的货物输送至细胞核。
T78352	N-acetylglucosamine-1-P uridyltransferase (AGX1) GlcNAc1pUT	Others	Others
	N-acetylglucosamine-1-P uridyltransferase (AGX1) (GlcNAc1pUT) 是具有双功能乙酰转移酶/尿苷转移酶活性的原核生物专有酶。该酶能结合GlcNAc-1-P与UTP，催化合成UDP-GlcNAc的尿苷酰转移反应。

化合物

Cat.No: T39710

Synonym: Vepdegestrant

Target: Estrogen Receptor/ERR, PROTACs

Cat.No: T6798

Synonym: 5-Aziridino-2,4-dinitrobenzamide,CB1954,NSC 115829

Target: DNA Alkylator/Crosslinker, DNA Alkylation

N-[3,5-bis(trifluoroMethyl)phenyl]-N'-[(9R)-6'-Methoxycinchonan-9-yl]- Thiourea

Cat.No: T7750

Synonym: N-[3,5-双(三氟甲基)苯基]-N′-[(9R)-6′-甲氧基-9-金鸡宁]硫脲

Target: Others

Cat.No: T17159

Synonym: NSC 39069,曲奥舒凡,Treosulphan

Target: DNA Alkylator/Crosslinker, DNA Alkylation

Cat.No: T15178

Target: Others, PROTACs

Sulfo-SMCC sodium

Cat.No: T18728

Target: Others, ADC Linker

Proguanil hydrochloride

Cat.No: T4382

Synonym: Paludrine hydrochloride,盐酸氯胍,Chlorguanide hydrochloride,Chloroquanil

Target: Others, Dehydrogenase, DNA/RNA Synthesis, Antifolate, Parasite

Cat.No: T26803

Synonym: Bibw22,Bibw-22

Target: Others

9-Azido-Neu5DAz

Cat.No: T19168

Target: Others

Aminooxy-PEG3-C2-NH-Boc

Cat.No: T14267

Target: Others

Cat.No: T19207

Target: Others

N-(Azido-PEG2)-N-Boc-PEG4-Boc

Cat.No: T16181

Target: Others

Cat.No: T28846

Synonym: AT-202,AT202,SR 16835,SR-16835

Target: Others

t-Boc-Aminooxy-PEG7-bromide

Cat.No: T18744

Target: Others

Cat.No: T70925

Target: Others

Batefenterol Succinate

Cat.No: T68272

Target: Others

Cat.No: T25140

Synonym: BCH2763,BCH-2763

Target: Others

FmocNH-PEG4-t-butyl acetate

Cat.No: T41024

Synonym: FmocNH-PEG4-t-butyl acetate

Target: Others

Cat.No: T40648

Target: Others

Cat.No: T34173

Target: Others

p-NH2-CHX-A"-DTPA

Cat.No: T81433

Target: Others

Azido-PEG4-hydrazide-Boc

Cat.No: T14449

Target: Others

N-Mal-N-bis(PEG4-NHS ester)

Cat.No: T16234

Target: Others

Azide-PEG3-Sulfone-PEG3-azide

Cat.No: T17469

Target: Others

m-PEG-acrylate (MW 30000)

Cat.No: T18080

Target: Others

PROTAC BRD9 Degrader-3

Cat.No: T81384

Target: PROTACs

Ald-Ph-amido-C2-PEG3-NH-Boc

Cat.No: T14163

Target: Others

N-Desthiobiotin-N-bis(PEG4-t-butyl ester)

Cat.No: T18413

Target: Others

Thiol-PEG-CH2COOH (MW 5000)

Cat.No: T18834

Target: Others

Fmoc-N-PEG36-acid

Cat.No: T17962

Target: Others

PROTAC BRD9 Degrader-2

Cat.No: T81385

Target: PROTACs

DST Crosslinker

Cat.No: T31584

Synonym: DST Cross linker,DST Cross-linker

Target: Others

PROTAC BRD9 Degrader-4

Cat.No: T77936

Target: PROTACs

Cat.No: T82537

Target: LYTACs

Dalutrafusp alfa

Cat.No: T77155

Cat.No: T11938L

Target: Others

Cat.No: T26049

Synonym: RB6145,RB-6145

Target: Others

Cat.No: T81779

Target: LYTACs

Cat.No: T69149

Target: Others

Cat.No: T31588

Synonym: Y 9138

Target: Others

Cat.No: T32026

Synonym: GYKI 13324,GYKI13324

Target: Others

p-SCN-Bn-TCMC HCl

Cat.No: T28464

Synonym: p-SCN-Bn-TCMC

Target: Others

di-Ellipticine-RIBOTAC

Cat.No: T82560

Target: PROTACs

Cat.No: T68942

Target: Others

Biotin-PEG-Biotin (MW 20000)

Cat.No: T82866

TAT-NSF222 Fusion Peptide

Cat.No: T81035

Bintrafusp alfa

Cat.No: T80588

Synonym: M7824,MSB0011359C

M3/PDE4 modulator-1

Cat.No: T79618

Target: Others

Cat.No: T81675

Synonym: AP1867-PEG2-JQ1,AP-PEG2-JQ1

N-acetylglucosamine-1-P uridyltransferase (AGX1)

Cat.No: T78352

Synonym: GlcNAc1pUT

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-00590	GlmU Protein, E. coli, Recombinant (His & Myc) glmU,Bifunctional protein GlmU	E. coli	E. coli
	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
TMPH-00176	PucL Protein, Bacillus subtilis, Recombinant (His & Myc) Uric acid degradation bifunctional protein PucL,puc...	Bacillus subtilis	E. coli
	Catalyzes two steps in the degradation of uric acid, i.e. the oxidation of uric acid to 5-hydroxyisourate (HIU) and the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin. PucL Protein, Bacillus subtilis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 64.0 kDa and the accession number is O32141.
TMPH-00589	SpoT Protein, E. coli, Recombinant (His & Myc) Bifunctional (p)ppGpp synthase/hydrolase SpoT,spoT	E. coli	E. coli
	In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response which coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes both the synthesis and degradation of ppGpp. The second messengers ppGpp and c-di-GMP together control biofilm formation in response to translational stress; ppGpp represses biofilm formation while c-di-GMP induces it. ppGpp activates transcription of CsrA-antagonistic small ...
TMPH-01008	PNKP Protein, Human, Recombinant (His & SUMO) Polynucleotide kinase-3'-phosphatase,PNKP,DNA 5'-kinase/3'-p...	Human	E. coli
	Plays a key role in the repair of DNA damage, functioning as part of both the non-homologous end-joining (NHEJ) and base excision repair (BER) pathways. Through its two catalytic activities, PNK ensures that DNA termini are compatible with extension and ligation by either removing 3'-phosphates from, or by phosphorylating 5'-hydroxyl groups on, the ribose sugar of the DNA backbone. PNKP Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The ...
TMPH-00188	BioAB Protein, Bacteroides fragilis, Recombinant (His & Myc) Adenosylmethionine-8-amino-7-oxononanoate aminotransferase B...	Bacteroides fragilis	E. coli
	Catalyzes two activities which are involved in the biotine biosynthesis: the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism, and the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). BioAB Protein, Bacteroides fragilis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The p...
TMPH-00160	Cytochrome P450 BM-3 Protein, Bacillus megaterium, Recombinant (His & Myc) cyp102A1,Bifunctional cytochrome P450/NADPH--P450 r...	Bacillus megaterium	E. coli
	Cytochrome P450 BM-3 Protein, Bacillus megaterium, Recombinant (His & Myc) is expressed in E. coli.
TMPH-01007	NDST1 Protein, Human, Recombinant (His & SUMO) Glucosaminyl N-deacetylase/N-sulfotransferase 1,[Heparan sul...	Human	E. coli
	NDST1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 73.5 kDa and the accession number is P52848.
TMPH-03057	Chorismate synthase Protein, Neurospora crassa, Recombinant (His) B7F21.10,NCU05420,aro-2,5-enolpyruvylshikimate-3-phosphate p...	Neurospora crassa	E. coli
	Bifunctional enzyme that possesses chorismate synthase and intrinsic flavin reductase activity, it uses NADPH to reduce FMN.
TMPH-00110	UGT72B1 Protein, Arabidopsis thaliana, Recombinant (His & Myc) Probable hydroquinone glucosyltransferase,Arbutin synthase,U...	Arabidopsis thaliana	E. coli
	Bifunctional O-glycosyltransferase and N-glycosyltransferase that can detoxify xenobiotics. Possesses high activity to metabolize the persistent pollutants 2,4,5-trichlorophenol (TCP) and 3,4-dichloroaniline (DCA). Also active on benzoates and benzoate derivatives in vitro. UGT72B1 Protein, Arabidopsis thaliana, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 60.4 kDa and the accession number is Q9M156.
TMPH-03605	CHOD Protein, Streptomyces sp., Recombinant (GST) choA,Cholesterol isomerase,CHOD,Cholesterol oxidase	Streptomyces	E. coli
	Bifunctional enzyme that catalyzes the oxidation of the 3-beta-hydroxy group of cholesterol and the isomerization of the double bond of the resulting product. CHOD Protein, Streptomyces sp., Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 81.9 kDa and the accession number is P12676.
TMPJ-00690	PGDS Protein, Human, Recombinant Glutathione-Requiring Prostaglandin D Synthase,PGDS,Glutathi...	Human	E. coli
	Hematopoietic Prostaglandin D Synthase (HPGDS) belongs to the GST superfamily and Sigma family. HPGDS contains one GST C-terminal domain and one GST N-terminal domain. HPGDS is highly expressed in adipose tissue, macrophages, and placenta, and it exists in the form of homodimer in living body. HPGDS is a cytosolic enzyme that isomerizes PGH(2). HPGDS is a bifunctional enzyme that catalyzes both the conversion of PGH2 to PGD2 and also shows low glutathione-peroxidase activity towards cumenehydrop...
TMPY-02201	Peroxiredoxin 6 Protein, Human, Recombinant (His) p29,PRX,1-Cys,HEL-S-128m,peroxiredoxin 6,NSGPx,AOP2,aiPLA2	Human	E. coli
	PRDX6, a member of antioxidant protein superfamily, plays an important role in oxidative stress, catabolism of lipids and phospholipid lipisomes. Peroxiredoxin 6 (PRDX6) is involved in redox regulation of the cell and is thought to be protective against oxidant injury. Peroxiredoxin 6 (PRDX6) is a bifunctional protein with both glutathione peroxidase (GPx) and iPLA2 activities，which are concomitantly increased with the expression of PRDX6. PRDX6 promoted lung tumor growth in an in vivo allograft...
TMPY-03976	EEF1E1 Protein, Human, Recombinant (His) eukaryotic translation elongation factor 1 ε 1,P18,eukaryoti...	Human	E. coli
	EEF1E1, also known as AIMP3 and p18, is a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, EEF1E1 is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. It is comprised of a bifunctional glutamyl-prolyl-tRNA synthase, the monospecific isoleucyl, leucyl, glutaminyl, methionyl, lysyl, arginyl and aspartyl-tRNA synthases, and three auxiliary proteins, EEF1E1/p18, AIMP2/p38 and AIMP1/p43. EEF1E1 also plays a positive role in ATM/AT...
TMPJ-00202	CD157 Protein, Human, Recombinant (hFc) Cyclic ADP-ribose hydrolase 2,cADPr hydrolase 2,ADP-ribosyl ...	Human	HEK293 Cells
	The cluster of differentiation (CD) system is a glycosyl phosphatidylinositol anchored membrane protein that belongs to the CD38 family.It is generally used in immunophynotyping. CD157 was discovered in a bone marrow stromal cell line where it facilitates pre-B-cell growth. CD157 is a bifunctional ectoenzyme that exhibits both ADP-ribosyl cyclase and cyclic ADP ribose hydrolase activities followed with CD38. It plays a role in rheumatoid arthritis (RA) due to its enhanced expression in RA-derive...
TMPY-03338	GSTZ1 Protein, Human, Recombinant (His) MAI,GSTZ1-1,glutathione S-transferase ζ 1,MAAI,GSTZ1,glutath...	Human	E. coli
	GSTZ1 (Glutathione S-Transferase Zeta 1) is a Protein Coding gene. 3 alternatively spliced human isoforms have been reported. GSTZ1 gene is a member of the glutathione S-transferase (GSTs) super-family which encodes multifunctional enzymes important in the detoxification of electrophilic molecules, including carcinogens, mutagens, and several therapeutic drugs, by conjugation with glutathione. GSTZ1 is a bifunctional protein that has minimal glutathione-conjugating activity with ethacrynic acid ...
TMPY-01680	Lumican Protein, Human, Recombinant (His) lumican,LDC,SLRR2D	Human	HEK293 Cells
	Lumican, a prototypic leucine-rich proteoglycan with keratan sulfate side chains, is a major component of the cornea, dermal, and muscle connective tissues. In these bifunctional molecules, the protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. Lumican is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican regulates collagenous matr...
TMPY-04474	PFKFB3 Protein, Human, Recombinant (His & GST) IPFK2,6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3,...	Human	Baculovirus Insect Cells
	Fructose-2,6-biphosphatase 3, also known as 6-phosphofructo-2-kinase or PFK2 or PFKFB3, is a potent activator of phosphofructokinase, which is a rate-limiting enzyme of glycolysis. Highly phosphorylated PFKFB3 protein was found in human tumor cells, vascular endothelial cells, and smooth muscle cells. Fructose 2,6-bisphosphate (Fru-2,6-BP) is an allosteric activator of 6-phosphofructo-1-kinase (PFK-1), a rate-limiting enzyme and essential control point in glycolysis. The concentration of PFK2 de...

重组蛋白

GlmU Protein, E. coli, Recombinant (His & Myc)

Cat.No: TMPH-00590

Species: E. coli

Expression System: E. coli

PucL Protein, Bacillus subtilis, Recombinant (His & Myc)

Cat.No: TMPH-00176

Species: Bacillus subtilis

Expression System: E. coli

SpoT Protein, E. coli, Recombinant (His & Myc)

Cat.No: TMPH-00589

Species: E. coli

Expression System: E. coli

PNKP Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01008

Species: Human

Expression System: E. coli

BioAB Protein, Bacteroides fragilis, Recombinant (His & Myc)

Cat.No: TMPH-00188

Species: Bacteroides fragilis

Expression System: E. coli

Cytochrome P450 BM-3 Protein, Bacillus megaterium, Recombinant (His & Myc)

Cat.No: TMPH-00160

Species: Bacillus megaterium

Expression System: E. coli

NDST1 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01007

Species: Human

Expression System: E. coli

Chorismate synthase Protein, Neurospora crassa, Recombinant (His)

Cat.No: TMPH-03057

Species: Neurospora crassa

Expression System: E. coli

UGT72B1 Protein, Arabidopsis thaliana, Recombinant (His & Myc)

Cat.No: TMPH-00110

Species: Arabidopsis thaliana

Expression System: E. coli

CHOD Protein, Streptomyces sp., Recombinant (GST)

Cat.No: TMPH-03605

Species: Streptomyces

Expression System: E. coli

PGDS Protein, Human, Recombinant

Cat.No: TMPJ-00690

Species: Human

Expression System: E. coli

Peroxiredoxin 6 Protein, Human, Recombinant (His)

Cat.No: TMPY-02201

Species: Human

Expression System: E. coli

EEF1E1 Protein, Human, Recombinant (His)

Cat.No: TMPY-03976

Species: Human

Expression System: E. coli

CD157 Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00202

Species: Human

Expression System: HEK293 Cells

GSTZ1 Protein, Human, Recombinant (His)

Cat.No: TMPY-03338

Species: Human

Expression System: E. coli

Lumican Protein, Human, Recombinant (His)

Cat.No: TMPY-01680

Species: Human

Expression System: HEK293 Cells

PFKFB3 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04474

Species: Human

Expression System: Baculovirus Insect Cells

Cat. No.	Product Name	Target	Signaling Pathways
TMIH-0457	Proguanil-d6 HCl
	Proguanil-d6 HCl 是 Proguanil HCl 的氘代化合物。Proguanil HCl 的 CAS 号为 637-32-1。Proguanil hydrochloride 是一种双胍类抗疟疾剂，在体内代谢形成环胍。它还是一种二氢叶酸还原酶抑制剂。

同位素标记化合物

Proguanil-d6 HCl

Cat.No: TMIH-0457

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