amyloid-beta peptide

Amyloid β Peptide (42-1)(human) acetate 是淀粉样蛋白 β 肽 (1-42) 的无活性形式。Amyloid β Peptide (42-1)(human) acetate 是由 42 个氨基酸组成的肽，其在阿尔茨海默病的发病机制中起关键作用。

GSNKGAIIGLM(131602-53-4(free base)) (Amyloid beta-peptide(25-35)) 是阿尔茨海默病淀粉样蛋白 β-肽的片段 Aβ(25-35)。

Beta-Sheet Breaker Peptide iAβ5 Acetate 抑制大鼠脑模型中的淀粉样蛋白生成。

Beta-Amyloid(1-14),mouse,rat is a 1 to 14 fragment of Amyloid-β peptide. This peptide is amino acids 1 to 14 fragment of Beta-Amyloid peptide.

Amyloid-β (25-35) (Aβ (25-35)) is an 11-residue fragment of the Aβ protein that retains the physical and biological characteristics of the full length peptide. It forms fibrils that react to thioflavin T and Congo red and are organized in a cross-β arrangement of β-strands similar to Aβ (1-40) and Aβ (1-42) fibrils. Aggregated Aβ (25-35) decreases the viability of rat adrenal PC12 cells. It also decreases the viability of primary rat cortical neurons at concentrations ranging from 1 nM to 30 μM. In vivo, intracerebral injection of Aβ (25-35) (20 nmol) in rats induces lesions of neuronal and tissue loss. Aggregated Aβ (25-35) administered intracerebroventricularly to rats induces learning and memory impairments in the Y-maze, novel object recognition, and contextual fear conditioning tests.

Amyloid precursor c-terminal peptide has the amino acid sequence Gly-Tyr-Glu-Asn-Pro-Thr-Tyr-Lys-Phe-Phe-Glu-Gln-Met-Gln-Asn. APP is best known as the precursor molecule whose proteolysis generates beta-amyloid (Aβ), a 37 to 49 amino acid peptide whose am

(Gly22)-amyloid beta-protein(1-40) (Arctic variant Ab40ARC (E22G)) 是用于阿尔茨海默病研究的肽。

[Asn23]-beta-Amyloid (1-42), iowa mutation 是具有生物活性的肽，与阿尔茨海默病中的一种严重神经病理状况——大脑淀粉样蛋白血管病 (CAA) 密切相关。这种变异是由于在 APP 694 位点发生了错义突变，其中 Asp 23 被 Asn 取代，导致的。该变异形式的β-淀粉样肽倾向于更快聚集，形成具有毒性的原纤维。

β-Amyloid (25-35) (Aβ25-35) 是一种阿尔茨海默氏淀粉样蛋白β肽的Aβ(25-35) 片段，在培养细胞中显示出神经毒性作用。

β-Amyloid peptide(16-20)，即 Amyloid-β(Abeta) 的氨基酸序列(KLVFF)部分，有效抑制 Abeta 原纤维形成，通过在 N 和 C 末端添加 RG-/-GR-NH2 残基增强其溶解性。

Amyloid-Forming peptide GNNQQNY是由酵母蛋白Sup35的N-末端朊病毒决定结构域中得来的七肽段，具有生物活性，并能形成淀粉样纤维。它的详细原子低聚结构之研究，使其成为揭示早期聚集阶段的理想模型。GNNQQNY二聚体以三种稳定构形存在：寄存器内并排、寄存器外并排和反向并排。对准的平行二聚体其β-pleated sheet结构中肽链间氢键较少，强调了疏水作用的重要性，相较于反向并排结构有更高的构象熵。

β-Amyloid 15-21 acetate (Beta-Amyloid(15-21) acetate) 是 Amyloid-β 肽的片段，可用于神经系统疾病的研究。该片段参与β折叠形成。

β-Amyloid (1-42), human 是一种由 42 个氨基酸组成的肽，在阿尔茨海默病的发病机制中起关键作用。

β-Amyloid (31-35) (β-Amyloid 31-35) 是一种天然 Amyloid-β 肽的最短序列，具有神经毒性。

[Arg6]-β-Amyloid (1-42), england mutation 是具有生物活性的肽类化合物。β-Amyloid (1-42)中的英国 (H6R) 突变被认为与Alzheimer病的常染色体显性遗传形式有关，此突变影响了位点H6的相互作用。

(Pyr11)-Amyloid β-Protein (11-40) (A beta 11pE-40) 作为一种肽， 主要应用于阿尔茨海默病相关研究。

[Arg6]-β-Amyloid (1-40), England mutation 是具有生物活性的肽，与多种家族性常染色体显性阿尔茨海默病相关。特别地，这种英国突变，即位于第6位的His被Arg所替换，已报告可提高寡聚体形成动力学，加速初级纤维的种子化过程。此类寡聚体对神经元培养细胞展现出较高毒性。

Rat form of the beta-Amyloid (1-40) peptide

Antibodies corresponding to beta-amyloid (4-10) are effective in vivo inhibitors of cytotoxicity, amyloid plaque formation and special memory disturbances in mice. This peptide does not elicit an inflammatory response.

β-Amyloid (22-35) is a 14-aa peptide, shows aggregates and induces neurotoxicity in the hippocampal cells. Beta amyloid (22-35) is a synthetic truncated fragment of beta-amyloid peptide.

β-Amyloid (29-40), a fragment of the Amyloid-β peptide, possesses physical and chemical properties similar to those of viral protein fusion peptides. The C-terminal fragments (29-40 42) of Alzheimer's beta amyloid peptide can induce the fusion of liposomes.

β-Amyloid (1-16) rat 是β-淀粉样肽 (Abeta) 金属结合域的片段，含有三个与人类相异的氨基酸替代，因此在大鼠和小鼠中降低了 AD 样神经退行性变的易感性。

β-Amyloid (1-14),mouse,rat is a 1 to 14 fragment of Amyloid-β peptide. β-Amyloid (1-14),mouse,rat is produced through the proteolytic processing of a transmembrane protein, amyloid precursor protein (APP), by β- and γ-secretases. β-Amyloid (1-14),mouse,rat accumulation in the brain is proposed to be an early toxic event in the pathogenesis of Alzheimer’s disease, which is the most common form of dementia associated with plaques and tangles in the brain[1]. [1]. Chen GF, et al. Amyloid beta: structure, biology and structure-based therapeutic development. Acta Pharmacol Sin. 2017 Sep;38(9):1205-1235.

β-Amyloid (33-40) is a peptide consisting of amino acid of 33 to 40 of beta amyloid protein.

β-amyloid (15-21) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease. This fragment is involved in beta sheet formation.

β-Amyloid (35-42) is a peptide consisting of amino acid of 35 to 42 of beta amyloid protein.

This synthetic peptide consists of amino acids 1 to 17 of beta amyloid protein. This peptide can be employed in beta amyloid solubility studies.

β-Amyloid (11-22) is a peptide fragment of β-Amyloid. Beta-amyloid peptide (Abeta), the primary component of amyloid plaques in the brains of Alzheimer’s patients, is believed to be the cause of Alzheimer’s Disease (AD), the most common neurodegenerative disorder.

This is an N-terminal fragment of beta amyloid. It consists of amino acid residues 1 to 9. Truncated beta amyloid peptide (10-40) still forms amyloid fibrils and shows fibril polymorphism.

This synthetic peptide consists of amino acids 1 to 20 of beta amyloid protein.

This synthetic peptide consists of amino acids 22 to 40 of beta amyloid protein. This peptide sequence is often used in beta amyloid structure and aggregation studies.

neuroprotective peptide that binds to amyloid beta (Aβ)

This is a fragment of beta-amyloid peptide. It has amino acids 1 through 34.

[Asn23] β-Amyloid (1-40), Iowa mutation 是一种与重度大脑淀粉样蛋白血管病 (CAA) 相关的生物活性肽。该突变涉及 APP 694 位点的错义突变，Asp 23 位置的天冬酰胺被天冬酰氨酸取代。这种变异的 β-Amyloid 肽倾向于更快聚集，并形成有害的原纤维。

Amyloid (1-42), rat is a polypeptide composed of 42 amino acids. It is toxic to hippocampal slices and can be used in the study of alzheimer's disease.

β-Amyloid (13-27) is a synthetic peptide comprising amino acids 26 to 40 of the beta amyloid protein. It is utilized to study the kinetics of beta amyloid formation.

β-Amyloid (42-1), human is the inactive form of Amyloid β Peptide (1-42) which plays a key role in the pathogenesis of Alzheimer disease.

β-Amyloid (1-42), (rat mouse) (TFA) 是由 42 个氨基酸组成的多肽片段，可用于研究阿尔茨海默症。

(Asp37)-Amyloid β-Protein (1-42) 是野生型 Amyloid-beta (1-42) 肽的 G37D 突变体。