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Search Results for " urea "

Targets Recommended: Epoxide Hydrolase

113

抑制剂 & 化合物

20

天然产物

15

重组蛋白

3

同位素标记化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T8315	1-Cyclohexyl-3-dodecyl urea CDU,N-Cyclohexyl-N-dodecyl urea,NCND	Epoxide Hydrolase	Metabolism
	1-Cyclohexyl-3-dodecyl urea (NCND) 是高选择性的可溶性环氧化物水解酶 (sEH) 抑制剂，能够增强血管紧张素 II (Ang II) 高血压中的环氧二十碳三烯酸 (EETs) 水平，并降低血压。
T8925	Glu-urea-Lys
	Glu-urea-Lys 是一种靶向 PSMA 的分子支架，可用于研究前列腺特异性膜抗原的前列腺癌成像剂。
T0430	Imidazolidinyl urea Imidurea,咪唑烷基脲	Antibacterial; Antibiotic	Microbiology/Virology
	Imidazolidinyl urea (Imidurea) 在化妆品中作为抗菌防腐剂, 也用作甲醛释放剂。
T8123	Diazolidinyl urea Germall II,重氮烷基脲	Others; Antibacterial	Microbiology/Virology; Others
	Diazolidinyl urea (Germall II) 是一种甲醛释放防腐剂，用于化妆品和个人护理产品。它对大多数污染微生物，特别是假单胞菌都有效。
T3572	NSC 15364 1,3-Bis(4-aminophenyl)urea,NSC15364	Apoptosis; Others; VDAC	Apoptosis; Membrane transporter/Ion channel; Others
	NSC 15364 (1,3-Bis(4-aminophenyl)urea) 是一种 VDAC1寡聚化和细胞凋亡抑制剂。
T23818	BPU-11 Biphenyl Urea 11	Others	Others
	BPU-11 是一种 HCN4 CLP 配体，通过调节通道功能和完全消除 cAMP 诱导的 V1/2 变化来发挥作用。
T72077	Imidacloprid-urea	Others	Others
	Imidacloprid-urea 是吡虫啉的次级代谢产物。吡虫啉是一种有效且广泛使用的新烟碱类化合物，对谷物，蔬菜，茶叶和棉花的害虫具有抑制作用。Imidacloprid-urea 可以占据或阻断吡虫啉在土壤上的吸附位点，从而可能影响吡虫啉在环境中的去向、转运和生物利用度。
T39112	Propargyl-PEG2-urea-C3-triethoxysilane Propargyl-PEG2-urea-C3-triethoxysilane	Others	Others
	Propargyl-PEG2-urea-C3-triethoxysilane is a PEG-based PROTAC linker utilized for PROTAC synthesis.
T36321	C6 Urea Ceramide	Others	Others
	C6 urea ceramide is an inhibitor of neutral ceramidase.1 It increases total ceramide levels in wild-type mouse embryonic fibroblasts (MEFs) and in HT-29 colon cancer cells but not in MEFs lacking neutral ceramidase. It inhibits proliferation of, and induces apoptosis and autophagy in HT-29, but not non-cancerous RIE-1, cells when used at concentrations of 5 and 10 μM. C6 urea ceramide decreases total β-catenin, increases phosphorylated β-catenin, and induces colocalization of β-catenin with the ...
T22424	1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea	Apoptosis; STAT	Apoptosis; JAK/STAT signaling; Stem Cells
	SC-1 是一种 Sorafenib 的衍生物，可抑制 STAT3磷酸化，通过依赖 SHP-1 的 STAT3失活诱导细胞凋亡，具有抗癌作用。
T8562	A 425619 1-(4-(TRIFLUOROMETHYL)BENZYL)-3-(ISOQUINOLIN-5-YL)UREA	TRP/TRPV Channel	Membrane transporter/Ion channel
	A 425619 (1-(4-(TRIFLUOROMETHYL)BENZYL)-3-(ISOQUINOLIN-5-YL)UREA) 是一种有效的 TRPV1 拮抗剂。
T9832	(Rac)-EC5026 Urea, N-[3-fluoro-4-(trifluoromethoxy)phenyl]-N'-[1-(2-methyl-1-oxobutyl)-4-piperidinyl]-	Epoxide Hydrolase	Metabolism
	(Rac)-EC5026 ((Rac)-BPN-19186) 是一种有效的可溶性环氧水解酶 (sEH) 哌啶抑制剂，Ki 值为 0.06 nM。(Rac)-EC5026 可用于帕金森氏病和路易体痴呆 (DLB) 的研究。
T60124	1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(7-(1-methyl-1H-pyrazol-4-yl)-2,3,4,9-tetrahydro-1H-carbazol-3-yl)urea	TNF	Apoptosis
	1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(7-(1-methyl-1H-pyrazol-4-yl)-2,3,4,9-tetrahydro-1H-carbazol-3-yl)urea 是一种能够激动 TNF-α的化合物，可以诱导细胞分泌 TNF-α。
T33247	M-dimethylaminophenyl urea	Others	Others
	M-dimethylaminophenyl urea is a bioactive chemical.
T69361	C16-Urea-Ceramide	Others	Others
	C16-Urea-Ceramide s a neutral ceramidase (nCDase) inhibitor. It is a bioactive ceramide.
T35001	Urea, (5-amino-2-(octyloxy)benzyl)-	Others	Others
	Urea, (5-amino-2-(octyloxy)benzyl)- is a bioactive chemical.
T8925L	Glu-urea-Lys TFA(1025796-69-3 free base)	Others	Others
	Glu-urea-Lys TFA(1025796-69-3 free base)是一种 PSMA 抑制剂。
T35002	Urea, 1-(L-glucosyl)-2-thio- USAF D-8,L-Glucosethiourea	Others	Others
	Urea, 1-(L-glucosyl)-2-thio- is a bioactive chemical.
T67696	1-(2-fluorophenyl)-3-[5-(2-methoxyphenyl)	Others	Others
	1-(2-fluorophenyl)-3-[5-(2-methoxyphenyl)-1,3,4-thiadiazol-2-yl]urea 是一种化合物。
T9199	GLPG2938 1-(2-Ethoxy-6-(trifluoromethyl)pyridin-4-yl)-3-((5-methyl-6-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)pyridazin-3-yl)methyl)urea	S1P Receptor; LPL Receptor	GPCR/G Protein
	GLPG2938 (1-(2-Ethoxy-6-(trifluoromethyl)pyridin-4-yl)-3-((5-methyl-6-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)pyridazin-3-yl)methyl)urea) 是一种选择性 S1P2拮抗剂，可用于特发性肺纤维化的研究。
T7353	RSV604 (S)-1-(2-Fluorophenyl)-3-(2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)urea	RSV	Microbiology/Virology
	RSV604 ((S)-1-(2-Fluorophenyl)-3-(2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)urea) 是一种呼吸道合胞病毒抑制剂，可与 RSV 核蛋白结合，靶向核衣壳蛋白的 Kd 值为 1.6 μM。它对 RSV A 和 B 亚型的众多临床分离株有亚微摩尔活性，EC50平均值为 0.8 μM。
T20188	Polynoxylin Formaldehyde, urea polymer,Gabrite,Hygromull,HSDB 7203	Others	Others
	Polynoxylin is an antiseptic. It is used for local treatment of the skin and the mouth.
T66726	(2-Aminoethyl)urea hydrochloride	Others	Others
	(2-Aminoethyl)urea hydrochloride 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T66726，CAS号为 858001-69-1。
T29522L	(S)-ABT 102	TRP/TRPV Channel	Membrane transporter/Ion channel
	N-[(1S)-5-tert-butyl-2,3-dihydro-1H-inden-1-yl]-N'-1H-indazol-4-ylurea 是一种有效的TRPV1拮抗剂，其IC50为123 nM，可阻断capsaicin 对TRPV1的激活。
T84761	Glu-urea-Glu-NHS ester	Others	Others
	Glu-urea-Glu-NHS ester (compound 21) 是活性NHS Glu-urea-Glu，可作药效团与前列腺特异性膜抗原 (PSMA) 抑制剂结合。
T67700	1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)thieno[3,2-d]pyrimidin-2-yl)phenyl)-3-(pyridin-4-yl)urea	Others	Others
	1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)thieno[3,2-d]pyrimidin-2-yl)phenyl)-3-(pyridin-4-yl)urea 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T67700，CAS号为 1144075-47-7。
T64474	1,3-Bis(4-chloro-3-(trifluoromethyl)phenyl)urea	Others	Others
	1,3-Bis(4-chloro-3-(trifluoromethyl)phenyl)urea 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T64474，CAS号为 370-50-3。
T9310	mTOR inhibitor 13	PI3K; mTOR	PI3K/Akt/mTOR signaling
	mTOR inhibitor 13是一种选择性的mTOR 抑制剂，对mTOR 和PI3Kα的IC50分别为0.29nM 和119nM。
TNU1282	N-(4-Isopropyloxy phenyl)-N-(1H-pyrrol-2-ylmethyl)urea; flavoring agent, flavor modifier	Others	Others
	N-(4-Isopropyloxy phenyl)-N-(1H-pyrrol-2-ylmethyl)urea; flavoring agent, flavor modifier 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 TNU1282。
T20206	Oxymethurea CSI Paste,1'3-双羟甲基脲,Carbamol,Caurite,Dimethylolurea	Others	Others
	Oxymethurea (CSI Paste) 是一种改性尿素，可在农田中用作缓释肥料。
T20454	4-Chlorophenylurea NSC12971,NSC 12971,NSC-12971,4-氯苯基脲	Factor Xa	Metabolism
	4-Chlorophenylurea (NSC-12971) 是一种新型口服生物可利用的 Xa 因子抑制剂。
T7750	N-[3,5-bis(trifluoroMethyl)phenyl]-N'-[(9R)-6'-Methoxycinchonan-9-yl]- Thiourea N-[3,5-双(三氟甲基)苯基]-N′-[(9R)-6′-甲氧基-9-金鸡宁]硫脲	Others	Others
	N-[3,5-bis(trifluoroMethyl)phenyl]-N'-[(9R)-6'-Methoxycinchonan-9-yl]- Thiourea 是金鸡纳生物碱衍生的双功能催化剂。
T12156	N-(2-Chloro-6-methylphenyl)-N'-4-pyridinylurea	Others	Others
	N-(2-Chloro-6-methylphenyl)-N'-4-pyridinylurea 是一种抗惊厥剂，对广泛强直和部分性发作挛性具有潜在的研究价值。
T1251	Dicloralurea 双(三氯乙醛基)脲,Dichlorolurea,双 (三氯乙醛基) 脲,DCU	Others	Others
	Dicloralurea (DCU) 是一种兽用的食品添加剂，可用作生长刺激剂。
T0554	Dibutylurea	Others	Others
	Dibutylurea 用作医药中间体。
T23044	N,N'-Dicyclohexylurea DCU,1,3-Dicyclohexylurea,NSC 17013,Dicyclohexylurea,Dicyclohexylcarbodiamide,AURORA KA-3582,N,N-二环己脲	Epoxide Hydrolase	Metabolism
	N,N'-Dicyclohexylurea (AURORA KA-3582) 是一种可溶性环氧化物水解酶 (sEH) 抑制剂。
T0630	Ethyleneurea Imidazolidinone,2-咪唑烷酮	Others	Others
	Ethyleneurea (Imidazolidinone) 用作formaldehyde scavenger 和中间体。
T0418	Allylthiourea 阿利硫脲,N-Allylthiourea,Thiosinamine,烯丙基硫脲	MAO; Reactive Oxygen Species	Immunology/Inflammation; Metabolism; Neuroscience; NF-κB
	Allylthiourea (Thiosinamine) 是一种代谢抑制剂，专门抑制氨氧化。
T20110	Ethylene thiourea ETU,Imidazolidinethione,NCI C03372,NCIC03372,NCI-C03372,亚乙基硫脲	Others	Others
	Ethylene thiourea (NCIC03372) 是一种用于水果和蔬菜生产的农药。它还用作基于质子化学交换依赖性饱和转移的 MRI 研究的新型造影剂。
T77663	1-Benzyl-3-Phenylthiourea 1-Benzyl-3-Phenyl-2-Thiourea	Others	Others
	1-Benzyl-3-Phenylthiourea (1-Benzyl-3-Phenyl-2-Thiourea) 可用作检测神经毒剂和相关兴奋剂的传感材料。
T7543	S-(2-aminoethyl) Isothiourea (dihydrobromide)	NOS	Immunology/Inflammation
	S-(2-aminoethyl) Isothiourea (dihydrobromide) 是所有 NOS 异构体的非选择性抑制剂。对于人类 nNOS、eNOS 和 iNOS，Ki 值分别为 1.8、2.1 和 0.59 µM。
T67827	Urease Inhibitor 07	Others	Others
	Urease Inhibitor 07 是一种异取代金属蛋白酶抑制剂，对结核分枝杆菌H37Rv 菌株的潜在活性。
T73592	N′-(2-Chloroethyl)-N-(4-methylcyclohexyl)-N-nitrosourea	Others	Others
	N′-(2-Chloroethyl)-N-(4-methylcyclohexyl)-N-nitrosourea 具有抗肿瘤活性，可用于治疗 Lewis 肺癌和结肠肿瘤。
T0676	Hydroxyurea Hydroxycarbamide,羟基脲,nsc32065,nci-c04831	Apoptosis; HIV Protease; DNA/RNA Synthesis; Autophagy	Apoptosis; Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Proteases/Proteasome
	Hydroxyurea (Hydroxycarbamide) 是一种抗肿瘤剂，通过抑制核糖核苷二磷酸还原酶来抑制 DNA 合成。
T2716	1,3-Diphenylurea	Epoxide Hydrolase	Metabolism
	1,3-Diphenylurea 与环氧化物水解酶活性有关。
T22419	S-Methylisothiourea sulfate (S)-Methylisothiourea sulfate,S-甲基异硫脲硫酸盐,S-甲基异硫脲半硫酸盐	NOS; NO Synthase; HSV	Immunology/Inflammation; Microbiology/Virology
	S-Methylisothiourea sulfate ((S)-Methylisothiourea sulfate) 是一种选择性 iNOS 抑制剂，在感染性休克的啮齿动物模型中发挥有益作用。
T4169	N-Nitroso-N-methylurea 1-甲基-1-亚硝基脲,1-Methyl-1-nitrosourea,N-Methyl-N-nitrosourea,Methylnitrosourea	Others; DNA Alkylator/Crosslinker	DNA Damage/DNA Repair; Others
	N-Nitroso-N-methylurea 是一种具有烷基化、致癌和致突变特性的亚硝基脲化合物。它靶向多种动物器官，可引起各种癌症和变性疾病，可用于重氮甲烷合成。
T23300	S-Isopropylisothiourea hydrobromide	Others	Others
	S-Isopropylisothiourea hydrobromide is an iNOS inhibitor.
T78237	Urease-IN-6	Others	Others
	Urease-IN-6为一种高效Urease抑制剂，IC50值为14.2 μM，适用于消化性溃疡和胃溃疡研究。
T70565	Saussureamine C	Others	Others
	Saussureamine C is an inhibitor of H274Y and N294S mutants.

化合物

1-Cyclohexyl-3-dodecyl urea

Cat.No: T8315

Synonym: CDU,N-Cyclohexyl-N-dodecyl urea,NCND

Target: Epoxide Hydrolase

Cat.No: T8925

Imidazolidinyl urea

Cat.No: T0430

Synonym: Imidurea,咪唑烷基脲

Target: Antibacterial, Antibiotic

Diazolidinyl urea

Cat.No: T8123

Synonym: Germall II,重氮烷基脲

Target: Others, Antibacterial

Cat.No: T3572

Synonym: 1,3-Bis(4-aminophenyl)urea,NSC15364

Target: Apoptosis, Others, VDAC

Cat.No: T23818

Synonym: Biphenyl Urea 11

Target: Others

Imidacloprid-urea

Cat.No: T72077

Target: Others

Propargyl-PEG2-urea-C3-triethoxysilane

Cat.No: T39112

Synonym: Propargyl-PEG2-urea-C3-triethoxysilane

Target: Others

C6 Urea Ceramide

Cat.No: T36321

Target: Others

1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea

Cat.No: T22424

Target: Apoptosis, STAT

Cat.No: T8562

Synonym: 1-(4-(TRIFLUOROMETHYL)BENZYL)-3-(ISOQUINOLIN-5-YL)UREA

Target: TRP/TRPV Channel

Cat.No: T9832

Synonym: Urea, N-[3-fluoro-4-(trifluoromethoxy)phenyl]-N'-[1-(2-methyl-1-oxobutyl)-4-piperidinyl]-

Target: Epoxide Hydrolase

1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(7-(1-methyl-1H-pyrazol-4-yl)-2,3,4,9-tetrahydro-1H-carbazol-3-yl)urea

Cat.No: T60124

Target: TNF

M-dimethylaminophenyl urea

Cat.No: T33247

Target: Others

C16-Urea-Ceramide

Cat.No: T69361

Target: Others

Urea, (5-amino-2-(octyloxy)benzyl)-

Cat.No: T35001

Target: Others

Glu-urea-Lys TFA(1025796-69-3 free base)

Cat.No: T8925L

Target: Others

Urea, 1-(L-glucosyl)-2-thio-

Cat.No: T35002

Synonym: USAF D-8,L-Glucosethiourea

Target: Others

1-(2-fluorophenyl)-3-[5-(2-methoxyphenyl)

Cat.No: T67696

Target: Others

Cat.No: T9199

Synonym: 1-(2-Ethoxy-6-(trifluoromethyl)pyridin-4-yl)-3-((5-methyl-6-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)pyridazin-3-yl)methyl)urea

Target: S1P Receptor, LPL Receptor

Cat.No: T7353

Synonym: (S)-1-(2-Fluorophenyl)-3-(2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)urea

Target: RSV

Cat.No: T20188

Synonym: Formaldehyde, urea polymer,Gabrite,Hygromull,HSDB 7203

Target: Others

(2-Aminoethyl)urea hydrochloride

Cat.No: T66726

Target: Others

Cat.No: T29522L

Target: TRP/TRPV Channel

Glu-urea-Glu-NHS ester

Cat.No: T84761

Target: Others

1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)thieno[3,2-d]pyrimidin-2-yl)phenyl)-3-(pyridin-4-yl)urea

Cat.No: T67700

Target: Others

1,3-Bis(4-chloro-3-(trifluoromethyl)phenyl)urea

Cat.No: T64474

Target: Others

mTOR inhibitor 13

Cat.No: T9310

Target: PI3K, mTOR

N-(4-Isopropyloxy phenyl)-N-(1H-pyrrol-2-ylmethyl)urea; flavoring agent, flavor modifier

Cat.No: TNU1282

Target: Others

Cat.No: T20206

Synonym: CSI Paste,1'3-双羟甲基脲,Carbamol,Caurite,Dimethylolurea

Target: Others

4-Chlorophenylurea

Cat.No: T20454

Synonym: NSC12971,NSC 12971,NSC-12971,4-氯苯基脲

Target: Factor Xa

N-[3,5-bis(trifluoroMethyl)phenyl]-N'-[(9R)-6'-Methoxycinchonan-9-yl]- Thiourea

Cat.No: T7750

Synonym: N-[3,5-双(三氟甲基)苯基]-N′-[(9R)-6′-甲氧基-9-金鸡宁]硫脲

Target: Others

N-(2-Chloro-6-methylphenyl)-N'-4-pyridinylurea

Cat.No: T12156

Target: Others

Cat.No: T1251

Synonym: 双(三氯乙醛基)脲,Dichlorolurea,双 (三氯乙醛基) 脲,DCU

Target: Others

Cat.No: T0554

Target: Others

N,N'-Dicyclohexylurea

Cat.No: T23044

Synonym: DCU,1,3-Dicyclohexylurea,NSC 17013,Dicyclohexylurea,Dicyclohexylcarbodiamide,AURORA KA-3582,N,N-二环己脲

Target: Epoxide Hydrolase

Cat.No: T0630

Synonym: Imidazolidinone,2-咪唑烷酮

Target: Others

Cat.No: T0418

Synonym: 阿利硫脲,N-Allylthiourea,Thiosinamine,烯丙基硫脲

Target: MAO, Reactive Oxygen Species

Ethylene thiourea

Cat.No: T20110

Synonym: ETU,Imidazolidinethione,NCI C03372,NCIC03372,NCI-C03372,亚乙基硫脲

Target: Others

1-Benzyl-3-Phenylthiourea

Cat.No: T77663

Synonym: 1-Benzyl-3-Phenyl-2-Thiourea

Target: Others

S-(2-aminoethyl) Isothiourea (dihydrobromide)

Cat.No: T7543

Target: NOS

Urease Inhibitor 07

Cat.No: T67827

Target: Others

N′-(2-Chloroethyl)-N-(4-methylcyclohexyl)-N-nitrosourea

Cat.No: T73592

Target: Others

Cat.No: T0676

Synonym: Hydroxycarbamide,羟基脲,nsc32065,nci-c04831

Target: Apoptosis, HIV Protease, DNA/RNA Synthesis, Autophagy

1,3-Diphenylurea

Cat.No: T2716

Target: Epoxide Hydrolase

S-Methylisothiourea sulfate

Cat.No: T22419

Synonym: (S)-Methylisothiourea sulfate,S-甲基异硫脲硫酸盐,S-甲基异硫脲半硫酸盐

Target: NOS, NO Synthase, HSV

N-Nitroso-N-methylurea

Cat.No: T4169

Synonym: 1-甲基-1-亚硝基脲,1-Methyl-1-nitrosourea,N-Methyl-N-nitrosourea,Methylnitrosourea

Target: Others, DNA Alkylator/Crosslinker

S-Isopropylisothiourea hydrobromide

Cat.No: T23300

Target: Others

Cat.No: T78237

Target: Others

Saussureamine C

Cat.No: T70565

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T0738	Urea 尿素,Ureophil,Carbamide,E-Cardamoni,Carbonyldiamide	Others; DHFR; Wnt/beta-catenin; Arginase; Endogenous Metabolite; Carbonic Anhydrase	Cell Cycle/Checkpoint; Cytoskeletal Signaling; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Others; Stem Cells
	Urea (Carbonyldiamide) 在肝脏中由氨基酸脱氨产生的氨形成。它是蛋白质分解代谢的主要终代谢产物。
TN7143	1,3-Diphenethylurea N,N'-Diphenethylurea,1,3-bis(2-phenylethyl)urea,N,N'-Bis(phenethyl)urea,1,3-双(2-苯乙基)脲,ZINC150349,N,N'-bis(2-phenylethyl)urea	Others	Others
	1,3-Diphenethylurea (N,N'-Bis(phenethyl)urea) 是一种海洋来源的天然产物，存在于 Lissoclinum patella。
TN7150	Pygmaniline B 1,3-Bis-(2,4-dimethoxy-phenyl)-urea,1,3-bis(2,4-dimethoxyphenyl)urea,N,N'-bis(2,4-dimethoxyphenyl)urea	Others	Others
	Pygmaniline B (1,3-bis(2,4-dimethoxyphenyl)urea) 是一种海洋来源的天然产物，存在于Lichina pygmaea。
T0746	Orotic acid 乳清酸,Vitamin B13,6-Carboxyuracil	Nucleoside Antimetabolite/Analog; Dehydrogenase; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	Orotic acid (Vitamin B13) 是一种嘧啶核苷酸和 RNA 生物合成的前体，从线粒体二氢乳清酸脱氢酶 (DHODH) 中释放，通过细胞质 UMP 合酶转化为 UMP。它可引起大鼠肝脂肪变性和肝肿大，是尿素循环异常的常规新生儿筛查中的一种测量指标。
T3271	Orotic acid zinc 乳清酸锌二水合物,Orotic acid zinc salt dihydrate,Zinc Orotate	Nucleoside Antimetabolite/Analog; Others; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Others
	Orotic acid zinc (Zinc Orotate) 是一种嘧啶核苷酸和 RNA 生物合成的前体，从线粒体二氢乳清酸脱氢酶 (DHODH) 中释放，通过细胞质 UMP 合酶转化为 UMP。它可引起大鼠肝脂肪变性和肝肿大，是尿素循环异常的常规新生儿筛查中的一种测量指标。
T2O2701	L-Ornithine hydrochloride L(+)-Ornithine hydrochloride,(S)-2,5-Diaminopentanoic acid,L-鸟氨酸盐酸盐;L-2,5-二氨基戊酸盐酸盐;L-鸟氨酸单盐酸盐;鸟氨酸盐酸盐;L-盐酸鸟氨酸;L-鸟粪氨基酸盐酸盐	Others; Endogenous Metabolite	Metabolism; Others
	L-Ornithine hydrochloride ((S)-2,5-Diaminopentanoic acid) 通过提高能量消耗效率和促进氨的排泄而具有抗疲劳作用。它是尿素循环中的关键反应物之一。
TQ0054	Purpureaside C	Others	Others
	Purpureaside C 是一种酚类糖苷类，具有显着的促炎、免疫调节和抗菌作用。
T8020	Benzoyleneurea 亚苯甲酰基脲,2,4-喹唑啉二酮	Antibacterial	Microbiology/Virology
	Benzoyleneurea 拥有抗菌活性，常被用作合成新型 PGGTase-I 的抑制剂。
T40615	N,N'-Dimethylthiourea N,N-二甲基硫脲,DMTU	Antioxidant	oxidation-reduction
	N,N'-Dimethylthiourea (DMTU) 是一种分离自黑蒜的化合物。N,N'-Dimethylthiourea 具有口服活性的羟基自由基 (•OH) 的清除剂，通过活化的中性粒细胞在体外阻止 •OH 的产生。N,N'-Dimethylthiourea 通过发挥 •OH 清除和抗炎作用，防止水浸限制应激诱导的大鼠胃粘膜损伤。
T21213	Benzylurea AI3-61350,Benzylcarbamide,Phenylmethylurea,苄脲,1-Benzylurea,N-Benzylurea	Others	Others
	Benzylurea (AI3-61350) 竞争性地抑制脱氢酶/细胞分裂素氧化酶。
T80864	Virgaureagenin F
	Virgaureagenin F, 一种从Rhizoma bolbostemmae中提取的皂苷。
T5267	N-Acetyl-L-glutamic acid Ac-L-Glu-OH,N-乙酰-L-谷氨酰胺,N-Acetylglutamic acid	Others; Endogenous Metabolite	Metabolism; Others
	N-Acetyl-L-glutamic acid (Ac-L-Glu-OH) 是一种 N-Acyl-L-氨基酸，是动物细胞培养基的组成成分，是一种酿酒酵母和人类的代谢物。
T0925	Allantoin Glyoxyldiureide,尿囊素,5-Ureidohydantoin	Endogenous Metabolite; Imidazoline Receptor	Metabolism; Neuroscience
	Allantoin (Glyoxyldiureide) 是一种存在于尿液和植物中的尿素乙内酰脲，用于皮肤病制剂。
T5247	Trimethylamine N-oxide dihydrate 二水氧化三甲胺,TMANO Dihydrate	Others; Endogenous Metabolite	Metabolism; Others
	Trimethylamine N-oxide dihydrate (TMANO Dihydrate) 是内源性代谢产物的一种。
T2931	2-Amino-5-ureidopentanoic acid DL-Citrulline,Citrulline,瓜氨酸	Others; Endogenous Metabolite	Metabolism; Others
	2-Amino-5-ureidopentanoic acid (Citrulline) 存在于肝脏中，不是蛋白质的构成成分，为人体脲循环的一个重要中间物，可与鸟氨酸、精氨酸合用治疗高氨血症。
T5257	L-Homocitrulline 高瓜氨酸,Homo-L-citrulline,Homocitrulline	Others; Endogenous Metabolite	Metabolism; Others
	L-Homocitrulline (Homocitrulline) 是一种代谢物，可在尿素循环障碍患者的尿液中大量检测到。在某些情况下，由于尿素循环的鸟氨酸供应耗尽而导致的氨甲酰磷酸酯的积累可能是 L-Homocitrulline 和高精氨酸合成增强的原因。
T2O2731	L-Aspartic acid L-天冬氨酸,L-天冬氨酸；L-天冬碱;L-酰胺天冬酸；L-天冬酰胺一水物,Aspatofort,Asparagic acid	Others; Endogenous Metabolite	Metabolism; Others
	L-Aspartic acid (Aspatofort) 是一种氨基酸，是结肠特异性药物输送的前体药物。
T2924	Phloretin 根皮素,Dihydronaringenin,NSC 407292,RJC 02792	SGLT; transporter; Endogenous Metabolite	GPCR/G Protein; Metabolism
	Phloretin (NSC-407292) 是从苹果树叶中提取的一种查耳酮，具有抗炎、抗氧化和抗癌活性。它是真核尿素转运蛋白抑制剂，可阻断 VacA 介导的尿素和离子转运，有潜力用于类风湿性关节炎和过敏性气道炎症的相关研究。
T4728	4-Acetamidobutanoic acid N-acetyl GABA,4-ACETAMIDOBUTYRIC ACID,4-乙酰氨基丁酸	GABA Receptor; Endogenous Metabolite; Antibacterial	Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Neuroscience
	4-Acetamidobutanoic acid (4-ACETAMIDOBUTYRIC ACID) 可在血液、粪便和尿液以及人体前列腺组织中找到，也存在于从酵母到人类的所有真核生物中。它是GABA 衍生物，具有抗氧化和抗菌活性。
T4919	Ureidopropionic acid Carbamoyl-b-alanine,3-酰脲丙酸,3-Ureidopropionic acid	Endogenous Metabolite	Metabolism
	Ureidopropionic acid (3-Ureidopropionic acid) 是尿嘧啶代谢的中间体。更具体地说，它是二氢尿嘧啶的分解产物，由二氢嘧啶酶产生。它通过β -脲丙酸酶进一步分解为β -丙氨酸。尿素丙酸本质上是β -丙氨酸的尿素衍生物。高水平的尿丙酸存在于β -尿丙酸酶(UP)缺乏的个体中。嘧啶代谢中的酶缺乏与抗肿瘤药物5-氟尿嘧啶的严重毒性风险有关。

天然产物

Cat.No: T0738

Synonym: 尿素,Ureophil,Carbamide,E-Cardamoni,Carbonyldiamide

Target: Others, DHFR, Wnt/beta-catenin, Arginase, Endogenous Metabolite, Carbonic Anhydrase

1,3-Diphenethylurea

Cat.No: TN7143

Synonym: N,N'-Diphenethylurea,1,3-bis(2-phenylethyl)urea,N,N'-Bis(phenethyl)urea,1,3-双(2-苯乙基)脲,ZINC150349,N,N'-bis(2-phenylethyl)urea

Target: Others

Cat.No: TN7150

Synonym: 1,3-Bis-(2,4-dimethoxy-phenyl)-urea,1,3-bis(2,4-dimethoxyphenyl)urea,N,N'-bis(2,4-dimethoxyphenyl)urea

Target: Others

Cat.No: T0746

Synonym: 乳清酸,Vitamin B13,6-Carboxyuracil

Target: Nucleoside Antimetabolite/Analog, Dehydrogenase, Endogenous Metabolite

Orotic acid zinc

Cat.No: T3271

Synonym: 乳清酸锌二水合物,Orotic acid zinc salt dihydrate,Zinc Orotate

Target: Nucleoside Antimetabolite/Analog, Others, Endogenous Metabolite

L-Ornithine hydrochloride

Cat.No: T2O2701

Synonym: L(+)-Ornithine hydrochloride,(S)-2,5-Diaminopentanoic acid,L-鸟氨酸盐酸盐;L-2,5-二氨基戊酸盐酸盐;L-鸟氨酸单盐酸盐;鸟氨酸盐酸盐;L-盐酸鸟氨酸;L-鸟粪氨基酸盐酸盐

Target: Others, Endogenous Metabolite

Cat.No: TQ0054

Target: Others

Cat.No: T8020

Synonym: 亚苯甲酰基脲,2,4-喹唑啉二酮

Target: Antibacterial

N,N'-Dimethylthiourea

Cat.No: T40615

Synonym: N,N-二甲基硫脲,DMTU

Target: Antioxidant

Cat.No: T21213

Synonym: AI3-61350,Benzylcarbamide,Phenylmethylurea,苄脲,1-Benzylurea,N-Benzylurea

Target: Others

Virgaureagenin F

Cat.No: T80864

N-Acetyl-L-glutamic acid

Cat.No: T5267

Synonym: Ac-L-Glu-OH,N-乙酰-L-谷氨酰胺,N-Acetylglutamic acid

Target: Others, Endogenous Metabolite

Cat.No: T0925

Synonym: Glyoxyldiureide,尿囊素,5-Ureidohydantoin

Target: Endogenous Metabolite, Imidazoline Receptor

Trimethylamine N-oxide dihydrate

Cat.No: T5247

Synonym: 二水氧化三甲胺,TMANO Dihydrate

Target: Others, Endogenous Metabolite

2-Amino-5-ureidopentanoic acid

Cat.No: T2931

Synonym: DL-Citrulline,Citrulline,瓜氨酸

Target: Others, Endogenous Metabolite

L-Homocitrulline

Cat.No: T5257

Synonym: 高瓜氨酸,Homo-L-citrulline,Homocitrulline

Target: Others, Endogenous Metabolite

L-Aspartic acid

Cat.No: T2O2731

Synonym: L-天冬氨酸,L-天冬氨酸；L-天冬碱;L-酰胺天冬酸；L-天冬酰胺一水物,Aspatofort,Asparagic acid

Target: Others, Endogenous Metabolite

Cat.No: T2924

Synonym: 根皮素,Dihydronaringenin,NSC 407292,RJC 02792

Target: SGLT, transporter, Endogenous Metabolite

4-Acetamidobutanoic acid

Cat.No: T4728

Synonym: N-acetyl GABA,4-ACETAMIDOBUTYRIC ACID,4-乙酰氨基丁酸

Target: GABA Receptor, Endogenous Metabolite, Antibacterial

Ureidopropionic acid

Cat.No: T4919

Synonym: Carbamoyl-b-alanine,3-酰脲丙酸,3-Ureidopropionic acid

Target: Endogenous Metabolite

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-00800	UreA Protein, Helicobacter pylori, Recombinant (His) ureA,Urea amidohydrolase subunit alpha,	Helicobacter pylori	P. pastoris (Yeast)
	Ammonia produced by ureolysis increases the gastric pH thereby providing an environment permissive for colonization of the stomach.
TMPH-00799	UreA Protein, Helicobacter pylori, Recombinant (E. coli, His) Urea amidohydrolase subunit alpha,ureA,	Helicobacter pylori	E. coli
	Ammonia produced by ureolysis increases the gastric pH thereby providing an environment permissive for colonization of the stomach. UreA Protein, Helicobacter pylori, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 30.5 kDa and the accession number is P14916.
TMPH-00801	UreB Protein, Helicobacter pylori, Recombinant (His) Urease subunit beta,Urea amidohydrolase su...	Helicobacter pylori	E. coli
	Ammonia produced by ureolysis increases the gastric pH thereby providing an environment permissive for colonization of the stomach. UreB Protein, Helicobacter pylori, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 65.7 kDa and the accession number is P69996.
TMPH-02817	OTCase Protein, Mouse, Recombinant (His & SUMO) Ornithine carbamoyltransferase, mitochondrial,Otc,Ornithine ...	Mouse	E. coli
	Catalyzes the second step of the urea cycle, the condensation of carbamoyl phosphate with L-ornithine to form L-citrulline. The urea cycle ensures the detoxification of ammonia by converting it to urea for excretion.
TMPH-02560	CPS1 Protein, Mouse, Recombinant (His) Carbamoyl-phosphate synthetase I,CPS1,CPSase I,Carbamoyl-pho...	Mouse	E. coli
	Involved in the urea cycle of ureotelic animals where the enzyme plays an important role in removing excess ammonia from the cell.
TMPJ-01058	ARG2 Protein, Human, Recombinant (His) ARG2,Kidney-type arginase,Type II arginase,Arginase-2, mitoc...	Human	E. coli
	Arginase-2 (ARG2) is a member of the arginase family. Arginase is a manganese-containing enzyme which catalyzes the hydrolysis of arginine to ornithine and urea. ARG2 is highly expressed in kidney and prostate, not founded in the liver, heart and pancreas. ARG2 has been implicated in the regulation of the arginine/ornithine concentrations in the cell. ARG2 may take part in the regulation of extra-urea cycle arginine metabolism and in down-regulation of nitric oxide synthesis. The extrahepatic ar...
TMPH-01037	CPS1 Protein, Human, Recombinant (His) CPS1,CPSase I,Carbamoyl-phosphate synthetase I,Carbamoyl-pho...	Human	E. coli
	Involved in the urea cycle of ureotelic animals where the enzyme plays an important role in removing excess ammonia from the cell. CPS1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 20.5 kDa and the accession number is P31327.
TMPH-01817	OTCase Protein, Human, Recombinant (His & SUMO) Ornithine carbamoyltransferase, mitochondrial,OTC,Ornithine ...	Human	E. coli
	Catalyzes the second step of the urea cycle, the condensation of carbamoyl phosphate with L-ornithine to form L-citrulline. The urea cycle ensures the detoxification of ammonia by converting it to urea for excretion. OTCase Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 52.1 kDa and the accession number is P00480.
TMPJ-00732	ASS1 Protein, Human, Recombinant (His) Citrulline--Aspartate Ligase,Argininosuccinate Synthase,ASS1...	Human	E. coli
	Argininosuccinate Synthase (ASS1) is an urea cycle enzyme with a tetrameric structure composed of identical subunits. ASS1 is involved in the synthesis of arginine and catalyzes that condensation of citrulline and aspartate to argininosuccinate using ATP. ASS1 is important to the urea cycle as it catalyzes the important second last step in the arginine biosynthetic pathway. ASS1 mainly expressed in periportal hepatocytes, but also in most other body tissues. A deficiency of ASS1 causes citrullin...
TMPH-02524	Arginase-1/ARG1 Protein, Mouse, Recombinant (His) Arginase-1,Type I arginase,Liver-type arginase,Arg1	Mouse	P. pastoris (Yeast)
	Key element of the urea cycle converting L-arginine to urea and L-ornithine, which is further metabolized into metabolites proline and polyamides that drive collagen synthesis and bioenergetic pathways critical for cell proliferation, respectively; the urea cycle takes place primarily in the liver and, to a lesser extent, in the kidneys.; Functions in L-arginine homeostasis in nonhepatic tissues characterized by the competition between nitric oxide synthase (NOS) and arginase for the available i...
TMPH-03257	CPS1 Protein, Rat, Recombinant (His & Myc) Carbamoyl-phosphate synthase [ammonia], mitochondrial,CPSase...	Rat	E. coli
	Involved in the urea cycle of ureotelic animals where the enzyme plays an important role in removing excess ammonia from the cell. CPS1 Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 23.7 kDa and the accession number is P07756.
TMPH-02527	ASS1 Protein, Mouse, Recombinant (His & Myc) Ass,Citrulline--aspartate ligase,Ass1,Argininosuccinate synt...	Mouse	E. coli
	One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues. ASS1 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 5...
TMPJ-00731	Carbonic Anhydrase 1 Protein, Human, Recombinant (His) Carbonic Anhydrase B,Carbonate Dehydratase I,CA-I,Carbonic A...	Human	E. coli
	Carbonic Anhydrase 1 (CA1) is a cytosolic enzyme, belonging to the alpha-carbonic anhydrase family. It is highly expressed in erythrocytes and acts as an early marker for erythroid differentiation. Carbonic anhydrase 1 plays a improtant role in many biological processes such as calcification, cellular respiration, bone resorption, acid-base balance. It is activated by imidazole, histamine, L-adrenaline, L- and D-histidine, and L- and D-phenylalanine. At the same time, It is inhibited by sulfonam...
TMPH-02526	Arginase-2/ARG2 Protein, Mouse, Recombinant (His & SUMO) Arginase II,Kidney-type arginase,Type II arginase,Arg2,Argin...	Mouse	E. coli
	May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to nitric oxid synthase (NOS). Arginine metabolism is a critical regulator of innate and adaptive immune responses. Seems to be involved in negative regulation of the survival capacity of activated CD4(+) and CD8(+) T cells. May suppress inflammation-related signaling in asthmatic airway epithelium....
TMPY-03445	Aspartate Aminotransferase Protein, Human, Recombinant (His) ASTQTL1,glutamic-oxaloacetic transaminase 1, soluble,cCAT,cA...	Human	E. coli
	GOT1 (Glutamic-Oxaloacetic Transaminase 1) is a Protein Coding gene. GOT1 belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme that exists in cytoplasmic and mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology. GOT1 is an important regulator of levels of glut...

重组蛋白

UreA Protein, Helicobacter pylori, Recombinant (His)

Cat.No: TMPH-00800

Species: Helicobacter pylori

Expression System: P. pastoris (Yeast)

UreA Protein, Helicobacter pylori, Recombinant (E. coli, His)

Cat.No: TMPH-00799

Species: Helicobacter pylori

Expression System: E. coli

UreB Protein, Helicobacter pylori, Recombinant (His)

Cat.No: TMPH-00801

Species: Helicobacter pylori

Expression System: E. coli

OTCase Protein, Mouse, Recombinant (His & SUMO)

Cat.No: TMPH-02817

Species: Mouse

Expression System: E. coli

CPS1 Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02560

Species: Mouse

Expression System: E. coli

ARG2 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01058

Species: Human

Expression System: E. coli

CPS1 Protein, Human, Recombinant (His)

Cat.No: TMPH-01037

Species: Human

Expression System: E. coli

OTCase Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01817

Species: Human

Expression System: E. coli

ASS1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00732

Species: Human

Expression System: E. coli

Arginase-1/ARG1 Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02524

Species: Mouse

Expression System: P. pastoris (Yeast)

CPS1 Protein, Rat, Recombinant (His & Myc)

Cat.No: TMPH-03257

Species: Rat

Expression System: E. coli

ASS1 Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02527

Species: Mouse

Expression System: E. coli

Carbonic Anhydrase 1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00731

Species: Human

Expression System: E. coli

Arginase-2/ARG2 Protein, Mouse, Recombinant (His & SUMO)

Cat.No: TMPH-02526

Species: Mouse

Expression System: E. coli

Aspartate Aminotransferase Protein, Human, Recombinant (His)

Cat.No: TMPY-03445

Species: Human

Expression System: E. coli

Cat. No.	Product Name	Target	Signaling Pathways
T64482	Urea-13C
	Urea-13C 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T64482，CAS号为 58069-82-2。
TMIJ-0419	Ethylene thiourea-d4
	Ethylene thiourea-d4 是 Ethylene thiourea 的氘代化合物。Ethylene thiourea 的 CAS 号为 96-45-7。Ethylene thiourea 是一种用于水果和蔬菜生产的农药。它还用作基于质子化学交换依赖性饱和转移的 MRI 研究的新型造影剂。
T70313	Indoxyl Sulfate-d5 potassium salt
	Indoxyl sulfate-d5 is intended for use as an internal standard for the quantification of indoxyl sulfate by GC- or LC-MS. Indoxyl sulfate is a uremic toxin and a metabolite of tryptophan. It is formed via sulfation of indole, an intermediate generated from tryptophan by intestinal bacteria, by the sulfotransferase (SULT) isoform 1A1 variant 2 (SULT1A1*2) in the liver. Indoxyl sulfate activates the aryl hydrocarbon receptor (AhR) in HepG2 40/6 hepatoma cells (EC50 = 12.1 nM in a reporter assay). ...

同位素标记化合物

Cat.No: T64482

Ethylene thiourea-d4

Cat.No: TMIJ-0419

Indoxyl Sulfate-d5 potassium salt

Cat.No: T70313

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