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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T0695 |
Avobenzone
阿伏苯宗,Butyl methoxydibenzoylmethane,BF2AVB |
Apoptosis; Estrogen Receptor/ERR; Others | Apoptosis; Endocrinology/Hormones; Others |
Avobenzone 是一种二苯甲酰甲烷内分泌干扰物,可直接与雌激素受体 β 结合,起到雌激素激动剂的作用。它是紫外线波段皮肤光防护防晒霜中应用最广泛的滤光剂之一。 | |||
T39730 |
Datopotamab deruxtecan
Dato-DXd,DS-1062 |
Others; Antibody-Drug Conjugates (ADCs) | Antibody-drug Conjugate/ADC Related; Others |
Datopotamab deruxtecan (DS-1062; Dato-DXd) is an antibody-drug conjugate (ADC) that specifically targets trophoblast cell surface antigen 2 (TROP2). This compound exhibits high antitumor activity. |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-05033 |
5T4/TPBG Protein, Human, Recombinant (aa 60-345, His)
5T4AG,trophoblast glycoprotein,WAIF1,M6P1,5T4 |
Human | HEK293 Cells |
Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adult tissues. 5T4/TPBG Protein, Human, Recombinant (aa 60-345, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 33.1 kDa and the accession number is Q13641. | |||
TMPH-00278 |
Interferon tau-1/IFNT1 Protein, Bovine, Recombinant (E. coli, His)
Trophoblast antiluteolytic protein,IFNT1,Tropho... |
Bovine | E. coli |
Interferon tau-1/IFNT1 Protein, Bovine, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 23.8 kDa and the accession number is P15696. | |||
TMPY-06317 |
5T4/TPBG Protein, Human, Recombinant (aa 1-355, His)
trophoblast glycoprotein,WAIF1,5T4AG,M6P1,5T4 |
Human | HEK293 Cells |
Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adult tissues. 5T4/TPBG Protein, Human, Recombinant (aa 1-355, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.15 kDa and the accession number is NP_006661.1. | |||
TMPY-06191 |
5T4/TPBG Protein, Mouse, Recombinant (His)
trophoblast glycoprotein,WAIF1,5T4,AW495680 |
Mouse | HEK293 Cells |
Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adult tissues. 5T4/TPBG Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.2 kDa and the accession number is Q9Z0L0. | |||
TMPY-06214 |
5T4/TPBG Protein, Mouse, Recombinant (hFc)
trophoblast glycoprotein,AW495680,5T4,WAIF1 |
Mouse | HEK293 Cells |
Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adult tissues. 5T4/TPBG Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 62.5 kDa and the accession number is Q9Z0L0. | |||
TMPH-00279 |
Interferon tau-1/IFNT1 Protein, Bovine, Recombinant (His)
Trophoblastin,Trophoblast protein 1,Interf... |
Bovine | P. pastoris (Yeast) |
Interferon tau-1/IFNT1 Protein, Bovine, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 21.8 kDa and the accession number is P15696. | |||
TMPH-02436 |
5T4/TPBG Protein, Cynomolgus, Recombinant (E. coli, His & Myc)
TPBG,Trophoblast glycoprotein,Wnt-activated inhibit... |
Cynomolgus | E. coli |
May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. 5T4/TPBG Protein, Cynomolgus, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 41.9 kDa and the accession number is Q4R8Y9. | |||
TMPH-02437 |
5T4/TPBG Protein, Cynomolgus, Recombinant (His & Myc)
TPBG,WAIF1,Wnt-activated inhibitory factor 1,Trophoblast... |
Cynomolgus | HEK293 Cells |
May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. 5T4/TPBG Protein, Cynomolgus, Recombinant (His & Myc) is expressed in HEK293 mammalian cells with N-10xHis and C-Myc tag. The predicted molecular weight is 39.9 kDa and the accession number is Q4R8Y9. | |||
TMPH-03392 |
5T4/TPBG Protein, Rat, Recombinant (His & SUMO)
Wnt-activated inhibitory factor 1,Trophoblast glyco... |
Rat | E. coli |
May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. 5T4/TPBG Protein, Rat, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 51.8 kDa and the accession number is Q5PQV5. | |||
TMPH-00851 |
HSD3B1 Protein, Human, Recombinant (His & Myc)
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase ty... |
Human | E. coli |
HSD3B1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 33.4 kDa and the accession number is P14060. | |||
TMPY-03597 |
VIP Protein, Human, Recombinant (His)
PHM27,vasoactive intestinal peptide |
Human | HEK293 Cells |
VIP, or vasoactive intestinal peptide, is a neuropeptide of 28 amino acid residues that belongs to a glucagon/secretin superfamily, and it exerts its actions through three G-protein-coupled receptors (PAC1, VPAC1, and VPAC2). VIP is synthesized by trophoblast cells; it regulates trophoblast cell function and interaction with the major immune cell populations present in the pregnant uterus. | |||
TMPJ-00987 |
PLGF/PGF Protein, Mouse, Recombinant (His)
Plgf,PlGF-2,PGFL,PGF,SHGC-10760,D12S1900,Placenta growth fac... |
Mouse | HEK293 Cells |
Placental growth factor is a protein that in humans is encoded by the PGF gene. It is a secreted protein and belongs to the PDGF/VEGF growth factor family. The protein is a member of the VEGF (vascular endothelial growth factor) sub-family-a key molecule in angiogenesis and vasculogenesis, in particular during embryogenesis. The main source of PGF during pregnancy is the placental trophoblast. PGF is also expressed in many other tissues, including the villous trophoblast. | |||
TMPJ-00577 |
INSL3 Protein, Human, Recombinant (His)
RLNL,Insulin-like 3,RLF,Leydig insulin-like peptide,INSL3,Re... |
Human | HEK293 Cells |
Insulin-like 3 is a protein that in humans is encoded by the INSL3 gene. It is a secreted protein that belongs to the insulin family. It is expressed in prenatal and postnatal Leydig cells and found as well in the corpus luteum, trophoblast, fetal membranes and breast. It may act as a hormone to regulate growth and differentiation of gubernaculum, and thus mediating intra-abdominal testicular descent.It is a ligand for LGR8 receptor. | |||
TMPY-02378 |
14‑3‑3 theta/YWHAQ Protein, Human, Recombinant (GST)
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activati... |
Human | E. coli |
The recently identified 14-3-3 tau, whose corresponding gene name is YWHAQ, is in a hypoxia-treated human trophoblast cell line. YWHAQ may play a role in epigenetic regulation of placental genes in the onset of Preeclampsia (PE). Moreover, there was a closer relationship between blood pressure and methylation levels of the YWHAQ promoter. | |||
TMPK-00490 |
GM-CSFR alpha Protein, Cynomolgus, Recombinant (His)
CSF2RY,SMDP4,GMCSFR-α,GMR-alpha,CSF2RAY,CDw116,GM-CSF-R-alph... |
Cynomolgus | HEK293 Cells |
In the first trimester, the GM-CSF-R was found to be present on villous cytotrophoblast and all populations of extravillous trophoblast. Expression by villous syncytiotrophoblast was weak or absent, but this increased markedly by term. GM-CSF-R were also expressed by fetal Hofbauer cells within the mesenchyme of the chorionic villi and by uterine glandular epithelium and decidual macrophages within maternal decidua. GM-CSFR alpha Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mamm... | |||
TMPK-00254 |
GM-CSFR alpha Protein, Human, Recombinant (His & Avi), Biotinylated
GM-CSF-R-α,GMR-α,GMR-alpha,GM-CSF-R-alpha,CSF2R,GMCSFR-alpha... |
Human | HEK293 Cells |
In the first trimester, the GM-CSF-R was found to be present on villous cytotrophoblast and all populations of extravillous trophoblast. Expression by villous syncytiotrophoblast was weak or absent, but this increased markedly by term. GM-CSF-R were also expressed by fetal Hofbauer cells within the mesenchyme of the chorionic villi and by uterine glandular epithelium and decidual macrophages within maternal decidua. GM-CSFR alpha Protein, Human, Recombinant (His & Avi), Biotinylated is expressed... | |||
TMPJ-00054 |
PLGF-2 Protein, Human, Recombinant (His)
PlGF-2,PlGF2,PlGF,PGF,PGFL |
Human | HEK293 Cells |
Placental growth factor is a protein that in humans is encoded by the PGF gene. It is a secreted protein and belongs to the PDGF/VEGF growth factor family. Alternate splicing results in at least three human mature PlGF forms containing 131 (PlGF‑1), 152 (PlGF‑2), and 203 (PlGF‑3) amino acids (aa) respectively. PlGF is mainly found as a variably glycosylated, secreted, 55 ‑ 60 kDa disulfide linked homodimer.The protein is a member of the VEGF (vascular endothelial growth factor) sub-family-a key ... | |||
TMPK-00930 |
GM-CSFR alpha Protein, Mouse, Recombinant (His)
CSF2RAX,CSF2RX,CD116,CSF2RAY,GM-CSF-R-α,GMCSFR-α,GMCSFR-alph... |
Mouse | HEK293 Cells |
In the first trimester, the GM-CSF-R was found to be present on villous cytotrophoblast and all populations of extravillous trophoblast. Expression by villous syncytiotrophoblast was weak or absent, but this increased markedly by term. GM-CSF-R were also expressed by fetal Hofbauer cells within the mesenchyme of the chorionic villi and by uterine glandular epithelium and decidual macrophages within maternal decidua. GM-CSFR alpha Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian... | |||
TMPJ-00522 |
PSG9 Protein, Human, Recombinant (His)
PS-β-G-11,PS-β-G-9,PS-β-B,Pregnancy-specific β-1 glycoprotei... |
Human | HEK293 Cells |
Pregnancy-specific beta-1-glycoprotein 9(PSG9) is a secreted protein and contains 3 Ig-like C2-type (immunoglobulin-like) domains, 1 Ig-like V-type (immunoglobulin-like) domain. It is a member of the PSG family, a group of closely related secreted glycoproteins that are highly expressed in fetal placental syncytiotrophoblast cells. The members of the PSG protein family all have a characteristic N-terminal domain that is homologous to the immunoglobulin variable region. PSGs become detectable in ... | |||
TMPY-03786 |
PLAC9 Protein, Human, Recombinant (mFc)
placenta specific 9,PLAC9 |
Human | HEK293 Cells |
PLAC9 belongs to the PLAC9 family. PLAC9 gene is a placental-enriched gene. There are other two placental-enriched genes: Plac1 and Plac8. Plac1 is strongly expressed in all trophoblast-derived cells in the placenta and has been described in 2. Plac8 expression is restricted to the spongiotrophoblast layer during development, whereas PLAC9 is weakly expressed though highly enriched in placenta. For both, cDNAs with complete open reading frames were recovered and exon-intron structures inferred f... | |||
TMPH-02163 |
Syncytin-1 Protein, Human, Recombinant (His & SUMO)
Endogenous retrovirus group W member 1,Enverin,Env-W,Syncyti... |
Human | E. coli |
This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. May induce fusion through binding of SLC1A4 and SLC1A5.; Endogenous envelope proteins may have kept, lost or modified their original function during evolution. Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. The surface protein (SU) mediates receptor r... |