首页工具

登录

搜索结果

Search Results for " transported "

Targets Recommended: Adenosine Receptor

14

抑制剂 & 化合物

2

天然产物

1

化合物库

11

重组蛋白

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name
L2400	内分泌激素分子库		784 compounds
	784 种与内分泌系统相关的生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；

化合物库

内分泌激素分子库

Cat.No: L2400

Compounds: 784

Cat. No.	Product Name	Target	Signaling Pathways
T7736	2-Chloroadenosine	Adenosine Receptor	GPCR/G Protein; Neuroscience
	2-Chloroadenosine 是腺苷类似物，可防止大鼠海马缺血细胞长期丢失。它是尿苷内流 (Ki:33 μM) 的竞争性抑制剂，高亲和力与硝基苄基硫肌苷结合 (Ki:0.18 mM)。它是一种人红细胞核苷转运体的转运渗透剂。
T18957	D-Ala-Lys-AMCA hydrochloride	Others	Others
	D-Ala-Lys-AMCA hydrochloride 是发射蓝色荧光的质子偶联寡肽转运蛋白 1 (PEPT1) 的已知底物。 D-Ala-Lys-AMCA 可能被转运到 Caco-2 细胞和肝癌细胞中。
T38273	Paclobutrazol (2R,3R)-Paclobutrazol,多效唑,(R,R)-paclobutrazol,2R,3R-Paclobutrazol	Antifungal	Microbiology/Virology
	Paclobutrazol ((R,R)-paclobutrazol) 是一种含有三唑的植物生长延缓剂，能抑制赤霉素的生物合成。Paclobutrazol 还具有抗真菌 (antifungal) 活性。Paclobutrazol 能抑制脱落酸的合成，诱导植物的耐冷性植物。Paclobutrazol 通常用于赤霉素在植物生物学中作用的研究。
T23409	FM4-64 SynaptoRedTM C2	Others	Others
	FM4-64 (SynaptoRedTM C2) 是一种苯乙烯类染料，染色效果稳定，但在在水溶液中基本不发荧光。FM4-64与质膜双层结合后不能被动扩散进入细胞内部,必须通过主动运输的方式进行跨膜运输。FM4-64 可用于研究胞吞胞吐和囊泡运输。
T67931	[Tyr3]Octreotate	Others	Others
	[Tyr3]Octreotate 是一个含有8个氨基酸的长肽化合物，是具有共价键DOTA 双功能螯合剂。[Tyr3]Octreotate 与SSR2活性的NETs 的跨膜受体结合，并通过内吞作用主动运输到细胞中，可能会增加所需的双链DNA 断裂，是治疗肿瘤的潜在药物。
T18958	D-Ala-Lys-AMCA TFA (375822-19-8 free base) D-Ala-Lys-AMCA TFA	Others	Others
	D-Ala-Lys-AMCA TFA is a known substrate of proton-coupled oligopeptide transporter 1 (PEPT1) that emits blue fluorescence. D-Ala-Lys-AMCA TFA may be transported into Caco-2 cells and liver cancer cells.
T69268	BGC-638	Others	Others
	BGC-638, an analogue of BGC-945, is a thymidylate synthase inhibitor specifically transported into α-folate receptor (α-FR)Â–overexpressing tumors.
T18959	D-Ala-Lys-AMCA	Others	Others
	D-Ala-Lys-AMCA is a known substrate of proton-coupled oligopeptide transporter 1 (PEPT1) that emits blue fluorescence. D-Ala-Lys-AMCA may be transported into Caco-2 cells and liver cancer cells.
T32705	Levomefolate magnesium L-Methylfolate magnesium	Others	Others
	Levomefolate magnesium is the magnesium salt of the metabolite of folic acid (Vitamin B9) and it is a predominant active form of folate found in foods and in the blood circulation, accounting for 98% of folates in human plasma. It is transported across th
T82617	D-Ala-Lys-AMCA TFA
	D-Ala-Lys-AMCA是一个已知的PEPT1底物，具有发射蓝色荧光的性质。该化合物可被转运至肝癌细胞及Caco-2细胞。D-Ala-Lys-AMCA能够作为工具用于评估PEPT1的特异性底物或其抑制剂。
T36745	cDPCP	Others	Others
	cDPCP is a platinum-containing DNA-crosslinking agent.1Unlike cisplatin or oxaliplatin , cDPCP forms monofunctional DNA adducts. It is transported into cells by organic cation transporter 1 (OCT1) and OCT2, inhibiting proliferation of MDCK cells expressing the human transporters with IC50values of 8.1 and 1.5 μM, respectively. cDPCP inhibits RNA polymerase II-mediated transcription in a reporter assay using HeLa cells. It increases survival in murine S180 sarcoma and P388 leukemia models when ad...
T36807	Estradiol 17-(β-D-Glucuronide) (sodium salt hydrate)	Others	Others
	Estradiol 17-(β-D-glucuronide) (E217G) is an estrogen metabolite formed in the liver and subsequently excreted in bile.1It acts as a substrate of the multidrug resistance protein 2 (MRP2; Km= 75 μM), and through MRP2-mediated transport, functions as a cholestatic agent, decreasing bile flow.1,2In addition to binding to the MRP2 transport site, E217G has been shown to bind to an allosteric site that through positive cooperativity activates its own transportviaMRP2 and the transport of other MRP2 ...
T37743	N-octadecanoyl-L-Homoserine lactone	Others	Others
	Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production. Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which gener...
T37741	N-hexadecanoyl-L-Homoserine lactone C16-HSL,N-palmitoyl-L-Homoserine,N-hexadecanoyl-L-Homoserine lactone	Others	Others
	Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density.[1] This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production.[2] Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which...

化合物

2-Chloroadenosine

Cat.No: T7736

Target: Adenosine Receptor

D-Ala-Lys-AMCA hydrochloride

Cat.No: T18957

Target: Others

Cat.No: T38273

Synonym: (2R,3R)-Paclobutrazol,多效唑,(R,R)-paclobutrazol,2R,3R-Paclobutrazol

Target: Antifungal

Cat.No: T23409

Synonym: SynaptoRedTM C2

Target: Others

[Tyr3]Octreotate

Cat.No: T67931

Target: Others

D-Ala-Lys-AMCA TFA (375822-19-8 free base)

Cat.No: T18958

Synonym: D-Ala-Lys-AMCA TFA

Target: Others

Cat.No: T69268

Target: Others

Cat.No: T18959

Target: Others

Levomefolate magnesium

Cat.No: T32705

Synonym: L-Methylfolate magnesium

Target: Others

D-Ala-Lys-AMCA TFA

Cat.No: T82617

Cat.No: T36745

Target: Others

Estradiol 17-(β-D-Glucuronide) (sodium salt hydrate)

Cat.No: T36807

Target: Others

N-octadecanoyl-L-Homoserine lactone

Cat.No: T37743

Target: Others

N-hexadecanoyl-L-Homoserine lactone

Cat.No: T37741

Synonym: C16-HSL,N-palmitoyl-L-Homoserine,N-hexadecanoyl-L-Homoserine lactone

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T6S0095	Genkwanin 7-O-Methylapigenin,Puddumetin,Apigenin 7-methyl ether,芫花素	Virus Protease	Microbiology/Virology
	Genkwanin (Apigenin 7-methyl ether) 是一种O-甲基化黄酮，有抗炎活性，通过被动扩散和多药耐药蛋白介导的外排机制转运。
T5074	Cholesteryl palmitate	Others; Endogenous Metabolite	Metabolism; Others
	Cholesteryl palmitate 是一种慢性间质性肺炎的有用预后生物标志物。

天然产物

Cat.No: T6S0095

Synonym: 7-O-Methylapigenin,Puddumetin,Apigenin 7-methyl ether,芫花素

Target: Virus Protease

Cholesteryl palmitate

Cat.No: T5074

Target: Others, Endogenous Metabolite

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-00911	GPT Protein, Human, Recombinant (His) Glutamic--alanine transaminase 1,Glutamate pyruvate transami...	Human	E. coli
	Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate. Participates in cellular nitrogen metabolism and also in liver gluconeogenesis starting with precursors transported from skeletal muscles. GPT Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 58.5 kDa and the accession number is P24298.
TMPJ-00381	PIGR Protein, Human, Recombinant (hFc) Polymeric Immunoglobulin Receptor,Poly-Ig Receptor,Hepatocel...	Human	HEK293 Cells
	PIGR binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment.
TMPH-03248	ASGR1 Protein, Rat, Recombinant (His & Myc) Asialoglycoprotein receptor 1,ASGP-R 1,rHL-1,Asgr1,HL-1,Asgr...	Rat	HEK293 Cells
	Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface. ASGR1 Protein, Rat, Recombinant (His & Myc) is expressed in...
TMPH-02529	ASGR2 Protein, Mouse, Recombinant (His & Myc) ASGPR 2,HL-2,mHL-2,Asgr-2,Hepatic lectin 2,ASGP-R 2,Asialogl...	Mouse	E. coli
	Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface. ASGR2 Protein, Mouse, Recombinant (His & Myc) is expressed ...
TMPH-00895	Human adenovirus B serotype 3 Hexon protein (His & Myc) Hexon protein,Protein II,L3	HAdV-3	E. coli
	Major capsid protein that self-associates to form 240 hexon trimers, each in the shape of a hexagon, building most of the pseudo T=25 capsid. Assembled into trimeric units with the help of the chaperone shutoff protein. Transported by pre-protein VI to the nucleus where it associates with other structural proteins to form an empty capsid. Might be involved, through its interaction with host dyneins, in the intracellular microtubule-dependent transport of incoming viral capsid to the nucleus. Hum...
TMPJ-00193	TREML1 Protein, Human, Recombinant (hFc) TLT-1,Trem-Like Transcript 1 Protein,TLT1,Triggering Recepto...	Human	HEK293 Cells
	Triggering Receptor Expressed on Myeloid Cells-Like Protein 1 (TREML1) is a single-pass type I membrane protein. TREML1 precursor contains a 15 amino acid signal peptide, a 147 amino acid extracellular domain with an Ig-like V-type (immunoglobulin-like) domain, and 128 amino acid cytoplasmic domain. It can be expressed exclusively in platelets and megakaryocytes (MKs). It is a cell surface receptor that may play a role in the innate and adaptive immune response. TREML1 Sequestered in cytoplasmic...
TMPY-03747	Fucose Mutarotase Protein, Human, Recombinant (His) fucose mutarotase,FucM,C10orf125,FUCU	Human	E. coli
	FUOM, also known as fucose mutarotase and FucM, belongs to the RbsD / FucU family. FUOM is involved in the interconversion between alpha- and beta-L-fucoses. L-Fucose has two isforms: alpha-L-fucose (29.5%) and beta-L-fucose (7.5%). The beta-form is metabolized through the salvage pathway. GDP-L-fucose formed either by the de novo or salvage pathways is transported into the endoplasmic reticulum, where it serves as a substrate for N- and O-glycosylations by fucosyltransferases. Fucosylated struc...
TMPY-02579	NRN1 Protein, Human, Recombinant (His) NRN,dJ380B8.2,MGC44811,neuritin 1	Human	Baculovirus Insect Cells
	Neuritin 1 (NRN1) is a member of the neuritin family. Neuritin is a glycosylphosphatidylinositol-anchored protein induced by neural activity. It is expressed in postmitotic-differentiating neurons of the developing nervous system and a population of small-diameter neurons in the dorsal root ganglia and was anterogradely and retrogradely transported. Neuritin message is induced by neuronal activity and by the activity-regulated neurotrophins BDNF, nerve growth factor (NGF), and NT-3. Purified rec...
TMPY-03788	ATP1B1 Protein, Human, Recombinant (His) ATPase, Na+/K+ transporting, β 1 polypeptide,ATPase, Na+/K+ ...	Human	HEK293 Cells
	ATP1B1 belongs to the family of Na+/K+and H+/K+-ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. ATP1B1 is a subunit of Na+/K+-ATPase. Na+/K+-ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. Na+/K+-ATPase is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). ATP1B1 regulates, through assembly of alpha/beta heterodim...
TMPJ-01459	FGF-21 Protein, Cynomolgus, Recombinant (His) Fibroblast Growth Factor 21,FGF-21,FGF21	Cynomolgus	HEK293 Cells
	Fibroblast Growth Factor 21 (FGF21) is a growth factor that belongs to the FGF family. FGF family proteins play a central role during prenatal development and postnatal growth and regeneration of mamy tissues, by promoting cellular proliferation and differentiation. FGF21 is a potent activator of glucose uptake on adipocytes, protects animal from diet-induced obesity when overexpression in transgenic mice, and lower blood glucose and triglyceride levels when therapeutically adiministered to diab...
TMPH-02346	Influenza A H1N1 (strain A/USA:Iowa/1943) Matrix protein 1 (His & Myc) Matrix protein 1,M	H1N1	E. coli
	Plays critical roles in virus replication, from virus entry and uncoating to assembly and budding of the virus particle. M1 binding to ribonucleocapsids (RNPs) in nucleus seems to inhibit viral transcription. Interaction of viral NEP with M1-RNP is thought to promote nuclear export of the complex, which is targeted to the virion assembly site at the apical plasma membrane in polarized epithelial cells. Interactions with NA and HA may bring M1, a non-raft-associated protein, into lipid rafts. For...

重组蛋白

GPT Protein, Human, Recombinant (His)

Cat.No: TMPH-00911

Species: Human

Expression System: E. coli

PIGR Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00381

Species: Human

Expression System: HEK293 Cells

ASGR1 Protein, Rat, Recombinant (His & Myc)

Cat.No: TMPH-03248

Species: Rat

Expression System: HEK293 Cells

ASGR2 Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02529

Species: Mouse

Expression System: E. coli

Human adenovirus B serotype 3 Hexon protein (His & Myc)

Cat.No: TMPH-00895

Species: HAdV-3

Expression System: E. coli

TREML1 Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00193

Species: Human

Expression System: HEK293 Cells

Fucose Mutarotase Protein, Human, Recombinant (His)

Cat.No: TMPY-03747

Species: Human

Expression System: E. coli

NRN1 Protein, Human, Recombinant (His)

Cat.No: TMPY-02579

Species: Human

Expression System: Baculovirus Insect Cells

ATP1B1 Protein, Human, Recombinant (His)

Cat.No: TMPY-03788

Species: Human

Expression System: HEK293 Cells

FGF-21 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPJ-01459

Species: Cynomolgus

Expression System: HEK293 Cells

Influenza A H1N1 (strain A/USA:Iowa/1943) Matrix protein 1 (His & Myc)

Cat.No: TMPH-02346

Species: H1N1

Expression System: E. coli

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼