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Search Results for " thymidine "

Targets Recommended: Others

81

抑制剂 & 化合物

8

天然产物

6

重组蛋白

3

同位素标记化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T24609	Thymidine 3',5'-disphosphate Thymidine 3',5'-biphosphate,pdTp	Others	Others
	pdTp is a highly selective, small-molecule miRNA regulatory complex RISC subunit SND1 inhibitor.
T1513	Telbivudine NV 02B,L-Thymidine,Epavudine,替比夫定	Others; HBV; Reverse Transcriptase	Microbiology/Virology; Others
	Telbivudine (NV 02B) 是一种乙型肝炎病毒复制的抗病毒抑制剂，是一种具有口服活性的胸腺嘧啶核苷类似物。
T83821	Thymidine-5'-O-(α,β-methylene)diphosphate sodium α,β-Methylenethymidine diphosphate,Thymidine-5'-O-methylenediphosphate,TMP-CP,α,β-MTDP	Others	Others
	TMP-CP（Thymidine-5’-O-(α,β-methylene)diphosphate）是TDP的一种水解稳定衍生物，同时也是一种thymidine kinase抑制剂（Ki = 23 µM）。它已被用作α,β-methylene-2’-deoxythymidine 5’-triphosphate合成的前体，该合成物是DNA polymerase的一种不可切割底物。
T84987	3′-deoxy Thymidine 2',3'-Dideoxythymidine	Others	Others
	d2T, a nucleoside analog of thymidine, exhibits antiviral activity by inhibiting HIV replication in infected human peripheral blood mononuclear cells (PBMCs; EC50 = 0.17 µM). Additionally, 3′-deoxy Thymidine at concentrations of 1, 3, 10, or 30 µM significantly decreases viral plaque formation in CV-1 cells infected with herpes simplex virus 1 (HSV-1).
T73980	Thymidine 5′-diphosphate	Others	Others
	Thymidine 5′-diphosphate (dTDP) 是合成嘧啶的关键产物，通过胸苷酸激酶 (TMPK) 对 5'-单磷酸胸苷 (dTMP) 进行磷酸化反应生成，此过程需 ATP 与 Mg2+。进一步，dTDP 可被 TMPK 催化转化为胸苷 5'-三磷酸 (dTTP)。通过测量 dTDP 水平，可以评估 TMPK 活性。
T29393	3'-Deoxy-4-thiothymidine Thymidine, 3'-deoxy-4-thio-,Ddthds	Others	Others
	3'-Deoxy-4-thiothymidine can moderately active in protecting HIV-induced cytopathogenicity of MT-2 and CEM cells.
TNU1269	3’-O-(t-Butyldiphenylsilyl)thymidine	Others	Others
	3'-O-(t-Butyldiphenylsilyl)thymidine is a Nucleoside Derivative - Protected nucleoside w/NH2/OH open.
TNU1406	5’-Deoxy-5’-furfurylamino thymidine	Others	Others
	5'-Deoxy-5'-furfurylamino thymidine is a Nucleoside Derivative - 5'-Modified nucleoside.
TNU1396	3’,5’-di-O-benzoyl thymidine	Others	Others
	3',5'-di-O-benzoyl thymidine is a Nucleoside Derivative - Other modified nucleoside.
T40506	5'-O-DMT-dT 5'-O-DMT-dT,5'-O-(4,4'-Dimethoxytrityl)thymidine	Others	Others
	5'-O-DMT-dT (5'-O-(4,4'-Dimethoxytrityl)thymidine) is a nucleoside derivative that finds utility in oligonucleotide synthesis.
T73824	Thymidine 3',5'-diphosphate tetrasodium	Others	Others
	Thymidine 3',5'-diphosphate (Deoxythymidine 3′,5′-diphosphate) tetrasodium，为一种选择性抑制剂，主要针对葡萄球菌核酸酶及含1的都铎结构域(SND1，MicroRNA调控复合体RISC亚基)和[3,5-2H2]酪氨酸核酸酶([3,5-2H2] tyrosyl nuclease)。此化合物还展示了抗肿瘤活性，并可在生化反应中作为催化剂使用。
TNU0727	3’-O-t-Bulyldimethylsilyl thymidine	Others	Others
	Nucleosides - 2’-deoxynucleoside
T83838	Sp-Thymidine-5'-O-(1-thiotriphosphate) sodium Sp-TTP-α-S	Others	Others
	Sp-Thymidine-5'-O-(1-thiotriphosphate)（Sp-TTP-α-S）是含硫核苷酸衍生物TTP-α-S的一个异构体。它能够结合HIV-1逆转录酶（在镁、锰酸盐和钴存在时，Kds分别为2.88、4.23和20.21 µM）。Sp-TTP-α-S抑制脱氧核苷酸三磷酸三磷酸水解酶SAMHD1（Ki为46 nM）。
T83837	Rp-Thymidine-5'-O-(1-thiotriphosphate) sodium Rp-dTTP-α-S	Others	Others
	Rp-Thymidine-5'-O-(1-thiotriphosphate) (Rp-TTP-α-S) 是含硫核苷酸衍生物 TTP-α-S 的一个异构体。它能与HIV-1逆转录酶结合（在镁、锰酸盐和钴存在下的Kds分别为45.7、27.32和39.44 µM）。
TNU1405	5’-Deoxy-5’-(4-morpholinyl)thymidine	Others	Others
	5'-Deoxy-5'-(4-morpholinyl)thymidine is a Nucleoside Derivative - 5'-Modified nucleoside.
TNU1606	3’-O-DMTr-thymidine 5’-CE phosphoramidite	Others	Others
	3'-O-DMTr-thymidine 5'-CE phosphoramidite is a Nucleoside Phosphoramidite.
TNU1323	3’,5’-Bis(O-t-butyldimethylsilyl)-4’-C-hydroxymethyl thymidine	Others	Others
	3',5'-Bis(O-t-butyldimethylsilyl)-4'-C-hydroxymethyl thymidine is a Nucleoside Derivative - 4'-Modified nucleoside; Protected nucleoside w/NH2/OH open.
T1454	Acyclovir Aciclovir,Acycloguanosine,阿昔洛韦	Apoptosis; DNA/RNA Synthesis; Antibacterial; Antibiotic; HSV	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Acyclovir (Aciclovir) 是鸟嘌呤类似物和具有口服活性的抗病毒剂。它对HSV-1(IC50为 0.85 μM)，HSV-2(IC50为 0.86 μM) 和水痘带状疱疹病毒有活性。
T0863	Idoxuridine IDU,碘苷,SKF 14287,5-Iodo-2′-deoxyuridine,NSC 39661,5-IUdR,Dendrid	Antifection; HSV	Microbiology/Virology
	Idoxuridine (Dendrid) 是一种抑制病毒 DNA 合成的脱氧尿苷类似物，用作抗病毒剂。
T27154	Dexelvucitabine D-D-4FC,DPC-817,RVT,beta-D-D-4FC,DFC	Reverse Transcriptase	Microbiology/Virology
	Dexelvucitabine (RVT) 是一种胞苷类似物，一种口服有活性的核苷逆转录酶抑制剂。它是一种 2'-脱氧胞苷抗逆转录病毒剂。它是一种有效的抗 HIV-1病毒剂，这些病毒聚合酶中含有胸苷类似物和/或 M184V 突变。
T19101	2'-Fluorothymidine 2'-Deoxy-2'-fluoro-5-Methyluridine,2'-Deoxy-2'-fluoro-5-Methyluridine	Others	Others
	2'-Fluorothymidine(2'-Deoxy-2'-fluoro-5-Methyluridine) 属于胸腺嘧啶 (TdR) 和甲基尿苷的同工酶，是具有高度选择性的 2 型胸苷激酶 (TK2) 的底物。
T1663	Deoxythymidine triphosphate	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Deoxythymidine triphosphate 用于体内 DNA 合成的四种核苷三磷酸之一。
TNU0977	4-Thiothymidine	Apoptosis	Apoptosis
	4-Thiothymidine is a Nucleoside Derivative - Thio-nucleoside, 5-Modified pyrimidine nucleoside.
T19530	Pseudothymidine 5-Methyl-2'-Deoxypseudouridin	Others	Others
	Pseudothymidine is a C-nucleoside analog of thymidine.
T40467	Deoxythymidine-5'-triphosphate dTTP,脱氧胸苷三磷酸	Others	Others
	Deoxythymidine-5'-triphosphate (dTTP) is a nucleoside triphosphate involved in DNA synthesis.
TNU1048	3’-Bromo-3’-deoxythymidine	Others	Others
	3'-Bromo-3'-deoxythymidine is a Nucleoside Derivative - Halo-nucleoside, 2',3'-Dideoxy nucleoside.
TNU1404	5’-Deoxy-5’-N-(2-chloroethyl)aminothymidine	Others	Others
	5'-Deoxy-5'-N-(2-chloroethyl)aminothymidine is a Nucleoside Derivative - 5'-Modified nucleoside.
T32816	L-Lysine, 5'-ester with 3'-azido-3'-deoxythymidine	Others	Others
	L-Lysine, 5'-ester with 3'-azido-3'-deoxythymidine is a bioactive chemical.
TNU1567	2-Thiothymidine	Others	Others
	2-Thiothymidine is a Nucleoside Derivative - Thio-nucleoside.
TNU1139	2,3’-Anhydrothymidine	Others	Others
	2,3'-Anhydrothymidine is a Nucleoside Derivative - Anhydro-nucleoside.
T29431	4'-Azidothymidine 5'-triphosphate Adrt TP,Adrt-TP,AdrtTP	Others	Others
	4'-Azidothymidine 5'-triphosphate exerts selectively action on both reverse transcriptase of human immunodeficiency virus type 1 and human DNA polymerases alpha and beta.
TNU1403	5’-Deoxy-5’-N,N-diethylaminothymidine	Others	Others
	5'-Deoxy-5'-N,N-diethylaminothymidine is a Nucleoside Derivative - 5'-Modified nucleoside.
TNU1049	3’-Deoxy-3’-iodothymidine	Others	Others
	3'-Deoxy-3'-iodothymidine is a Nucleoside Derivative - Halo-nucleoside, 2',3'-Dideoxy nucleoside.
TNU1559	3’-O-Acetylthymidine	Others	Others
	3'-O-Acetylthymidine is a Nucleoside Derivative - Protected nucleoside with NH2/OH open.
TNU1046	5’-O-Triphenylmethyl-3’-deoxy-3’-chlorothymidine	Others	Others
	5'-O-Triphenylmethyl-3'-deoxy-3'-chlorothymidine is a Nucleoside Derivative - Halo-nucleoside, 2',3'-Dideoxy nucleoside.
T29430	4'-Azidothymidine ADRT	Others	Others
	4'-Azidothymidine exhibits potent and selective activity against the human immunodeficiency virus.
TNU1395	3’,5’-di-O-acetylthymidine	Others	Others
	3',5'-di-O-acetylthymidine is a Nucleoside Derivative - Other modified nucleoside.
TNU1189	N3-Methylthymidine	Others	Others
	N3-Methylthymidine is a Nucleoside Derivative - N-Methylated nucleoside.
TNU1324	4’-Methylthymidine	Others	Others
	4'-Methylthymidine is a Nucleoside Derivative - 4'-Modified nucleoside.
TNU1147	5’-Deoxy-5’-iodothymidine	Others; ADC Cytotoxin	Antibody-drug Conjugate/ADC Related; Others
	5'-Deoxy-5'-iodothymidine is a Nucleoside Derivative - 5'-Modified nucleoside, Halo-nucleoside.
TNU0075	2’-Chlorothymidine	Others	Others
	2'-Chlorothymidine is a Halo-nucleoside; 5-modified pyrimidine nucleoside.
TNU1090	5,6-Dihydrothymidine	Others	Others
	5,6-Dihydrothymidine is a Nucleoside Derivative - 5,6-Dihydrouridine.
TNU1402	5’-Deoxy-5’-N,N-dimethylaminothymidine	Others	Others
	5'-Deoxy-5'-N,N-dimethylaminothymidine is a Nucleoside Derivative - 5'-Modified nucleoside.
TNU1111	α-Azidothymidine	Others	Others
	Nucleoside Derivatives - Azido-nucleosides, 5-Modified pyrimidine nucleosides
TNU1322	3’-O-t-Bulyldimethylsilyl-4’-C-hydroxymethylthymidine	Others	Others
	3'-O-t-Bulyldimethylsilyl-4'-C-hydroxymethylthymidine is a Nucleoside Derivative - 4'-Modified nucleoside.
TNU1251	5’-Amino-5’-deoxythymidine	Others	Others
	5'-Amino-5'-deoxythymidine is a Nucleoside Derivative - 5'-Deoxy nucleoside; 5'-Modified nucleoside; Amino nucleoside.
TNU0946	5'-DMTr-2,2'-anhydrothymidine	Others	Others
	Nucleoside Derivatives - Anhydro-nucleosides, 5-Modified pyrimidine nucleosides; Protected nucleosides with NH2/OH group
TNU1148	4’,5’-Didehydro-5’-deoxythymidine	Others	Others
	4',5'-Didehydro-5'-deoxythymidine is a Nucleoside Derivative - 5'-Modified nucleoside, Didehydro-nucleoside.
TNU0789	3-epi-Azido-3-deoxythymidine	Others	Others
	3’-N-modified nucleoside; Azido-nucleoside
TNU1149	5’-Azido-5’-deoxythymidine	Others	Others
	Nucleoside Derivatives - 5’-Modified nucleosides, Azido-nucleosides; Drugs and Inhibitors; Inhibitor of mycobacterium tuberculosis monophosphate kinase (TMPKmt)

化合物

Thymidine 3',5'-disphosphate

Cat.No: T24609

Synonym: Thymidine 3',5'-biphosphate,pdTp

Target: Others

Cat.No: T1513

Synonym: NV 02B,L-Thymidine,Epavudine,替比夫定

Target: Others, HBV, Reverse Transcriptase

Thymidine-5'-O-(α,β-methylene)diphosphate sodium

Cat.No: T83821

Synonym: α,β-Methylenethymidine diphosphate,Thymidine-5'-O-methylenediphosphate,TMP-CP,α,β-MTDP

Target: Others

3′-deoxy Thymidine

Cat.No: T84987

Synonym: 2',3'-Dideoxythymidine

Target: Others

Thymidine 5′-diphosphate

Cat.No: T73980

Target: Others

3'-Deoxy-4-thiothymidine

Cat.No: T29393

Synonym: Thymidine, 3'-deoxy-4-thio-,Ddthds

Target: Others

3’-O-(t-Butyldiphenylsilyl)thymidine

Cat.No: TNU1269

Target: Others

5’-Deoxy-5’-furfurylamino thymidine

Cat.No: TNU1406

Target: Others

3’,5’-di-O-benzoyl thymidine

Cat.No: TNU1396

Target: Others

Cat.No: T40506

Synonym: 5'-O-DMT-dT,5'-O-(4,4'-Dimethoxytrityl)thymidine

Target: Others

Thymidine 3',5'-diphosphate tetrasodium

Cat.No: T73824

Target: Others

3’-O-t-Bulyldimethylsilyl thymidine

Cat.No: TNU0727

Target: Others

Sp-Thymidine-5'-O-(1-thiotriphosphate) sodium

Cat.No: T83838

Synonym: Sp-TTP-α-S

Target: Others

Rp-Thymidine-5'-O-(1-thiotriphosphate) sodium

Cat.No: T83837

Synonym: Rp-dTTP-α-S

Target: Others

5’-Deoxy-5’-(4-morpholinyl)thymidine

Cat.No: TNU1405

Target: Others

3’-O-DMTr-thymidine 5’-CE phosphoramidite

Cat.No: TNU1606

Target: Others

3’,5’-Bis(O-t-butyldimethylsilyl)-4’-C-hydroxymethyl thymidine

Cat.No: TNU1323

Target: Others

Cat.No: T1454

Synonym: Aciclovir,Acycloguanosine,阿昔洛韦

Target: Apoptosis, DNA/RNA Synthesis, Antibacterial, Antibiotic, HSV

Cat.No: T0863

Synonym: IDU,碘苷,SKF 14287,5-Iodo-2′-deoxyuridine,NSC 39661,5-IUdR,Dendrid

Target: Antifection, HSV

Dexelvucitabine

Cat.No: T27154

Synonym: D-D-4FC,DPC-817,RVT,beta-D-D-4FC,DFC

Target: Reverse Transcriptase

2'-Fluorothymidine

Cat.No: T19101

Synonym: 2'-Deoxy-2'-fluoro-5-Methyluridine,2'-Deoxy-2'-fluoro-5-Methyluridine

Target: Others

Deoxythymidine triphosphate

Cat.No: T1663

Target: DNA/RNA Synthesis

4-Thiothymidine

Cat.No: TNU0977

Target: Apoptosis

Pseudothymidine

Cat.No: T19530

Synonym: 5-Methyl-2'-Deoxypseudouridin

Target: Others

Deoxythymidine-5'-triphosphate

Cat.No: T40467

Synonym: dTTP,脱氧胸苷三磷酸

Target: Others

3’-Bromo-3’-deoxythymidine

Cat.No: TNU1048

Target: Others

5’-Deoxy-5’-N-(2-chloroethyl)aminothymidine

Cat.No: TNU1404

Target: Others

L-Lysine, 5'-ester with 3'-azido-3'-deoxythymidine

Cat.No: T32816

Target: Others

2-Thiothymidine

Cat.No: TNU1567

Target: Others

2,3’-Anhydrothymidine

Cat.No: TNU1139

Target: Others

4'-Azidothymidine 5'-triphosphate

Cat.No: T29431

Synonym: Adrt TP,Adrt-TP,AdrtTP

Target: Others

5’-Deoxy-5’-N,N-diethylaminothymidine

Cat.No: TNU1403

Target: Others

3’-Deoxy-3’-iodothymidine

Cat.No: TNU1049

Target: Others

3’-O-Acetylthymidine

Cat.No: TNU1559

Target: Others

5’-O-Triphenylmethyl-3’-deoxy-3’-chlorothymidine

Cat.No: TNU1046

Target: Others

4'-Azidothymidine

Cat.No: T29430

Synonym: ADRT

Target: Others

3’,5’-di-O-acetylthymidine

Cat.No: TNU1395

Target: Others

N3-Methylthymidine

Cat.No: TNU1189

Target: Others

4’-Methylthymidine

Cat.No: TNU1324

Target: Others

5’-Deoxy-5’-iodothymidine

Cat.No: TNU1147

Target: Others, ADC Cytotoxin

2’-Chlorothymidine

Cat.No: TNU0075

Target: Others

5,6-Dihydrothymidine

Cat.No: TNU1090

Target: Others

5’-Deoxy-5’-N,N-dimethylaminothymidine

Cat.No: TNU1402

Target: Others

α-Azidothymidine

Cat.No: TNU1111

Target: Others

3’-O-t-Bulyldimethylsilyl-4’-C-hydroxymethylthymidine

Cat.No: TNU1322

Target: Others

5’-Amino-5’-deoxythymidine

Cat.No: TNU1251

Target: Others

5'-DMTr-2,2'-anhydrothymidine

Cat.No: TNU0946

Target: Others

4’,5’-Didehydro-5’-deoxythymidine

Cat.No: TNU1148

Target: Others

3-epi-Azido-3-deoxythymidine

Cat.No: TNU0789

Target: Others

5’-Azido-5’-deoxythymidine

Cat.No: TNU1149

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
TWP2911	Thymidine beta-胸苷,5-Methyldeoxyuridine,Deoxyribothymidine,DThyd,NSC 21548,Thymidin	Others; DNA/RNA Synthesis; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Others
	Thymidine (DThyd) 是一种细胞同步剂，是脱氧核糖核酸的特殊前体。它可在 DNA 复制前在 G1/S 边界阻滞细胞，是DNA 合成抑制因子。
T21552	5-deoxy Thymidine 5'-脱氧胸苷,5'-Deoxythymidine,Thymidine, 5'-deoxy-1-[(2R,4S,5R)-4-hydroxy-5-methyloxolan-2-yl]-5-methylpyrimidine-2,4-dione	Others	Others
	5-deoxy Thymidine (5'-Deoxythymidine) 是5'位被氢取代的胸苷形式。它对枯草芽孢杆菌和金黄色葡萄球菌的活性有效。
T4730	Thymidine-5'-monophosphate disodium salt 胸苷酸二钠,Thymidine 5'-monophosphate disodium salt,TMP DISODIUM SALT	Others; Endogenous Metabolite	Metabolism; Others
	Thymidine-5'-monophosphate disodium salt (TMP DISODIUM SALT) 是内源性代谢产物的一种。
T9086	Deoxythymidine-5'-triphosphate trisodium dTTP trisodium salt,thymidine 5'-(trisodium hydrogen triphosphate),胸苷-5'-三磷酸三钠盐,脱氧胸苷三磷酸三钠盐,Deoxythymidine-5'-triphosphate (dTTP) trisodium salt	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Deoxythymidine-5'-triphosphate trisodium (Deoxythymidine-5'-triphosphate(dTTP) trisodium salt) 是四种天然脱氧核苷酸之一，用于通过 DNA 聚合酶和逆转录酶生物合成脱氧核糖核酸。
T80989	Thymidine-5'-diphosphate-L-rhamnose
	Thymidine-5'-diphosphate-L-rhamnose 可从金褐藻 (Occhromonas malhamensis) 提取。
T4809	Pyrimidine 嘧啶,Metadiazine	Others; Endogenous Metabolite	Metabolism; Others
	Pyrimidine (Metadiazine) 是内源性代谢产物的一种。
TN4944	Santamarine	Caspase	Apoptosis; Proteases/Proteasome
	Santamarine has significant anticancer activity, can inhibit L1210 cells because of its cytotoxic,cytostatic and blocking mitosis and reducing uptake of thymidine. Santamarine and reynosin show bactericidal activity against clinical strains of Mycobacterium tuberculosis.
TMA0918	Neochamaejasmine A	Caspase	Apoptosis; Proteases/Proteasome
	Neochamaejasmin A can inhibit cellular (3)H-thymidine incorporation (IC 50 12.5 microg/mL) and subsequent proliferation of human prostate cancer LNCaP cells, it blocks cell cycle progression at the G1 phase by activating the p21 protein and ultimately pro

天然产物

Cat.No: TWP2911

Synonym: beta-胸苷,5-Methyldeoxyuridine,Deoxyribothymidine,DThyd,NSC 21548,Thymidin

Target: Others, DNA/RNA Synthesis, Endogenous Metabolite

5-deoxy Thymidine

Cat.No: T21552

Synonym: 5'-脱氧胸苷,5'-Deoxythymidine,Thymidine, 5'-deoxy-1-[(2R,4S,5R)-4-hydroxy-5-methyloxolan-2-yl]-5-methylpyrimidine-2,4-dione

Target: Others

Thymidine-5'-monophosphate disodium salt

Cat.No: T4730

Synonym: 胸苷酸二钠,Thymidine 5'-monophosphate disodium salt,TMP DISODIUM SALT

Target: Others, Endogenous Metabolite

Deoxythymidine-5'-triphosphate trisodium

Cat.No: T9086

Synonym: dTTP trisodium salt,thymidine 5'-(trisodium hydrogen triphosphate),胸苷-5'-三磷酸三钠盐,脱氧胸苷三磷酸三钠盐,Deoxythymidine-5'-triphosphate (dTTP) trisodium salt

Target: DNA/RNA Synthesis

Thymidine-5'-diphosphate-L-rhamnose

Cat.No: T80989

Cat.No: T4809

Synonym: 嘧啶,Metadiazine

Target: Others, Endogenous Metabolite

Cat.No: TN4944

Target: Caspase

Neochamaejasmine A

Cat.No: TMA0918

Target: Caspase

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPK-01386	TK1 Potein, Canine, Recombinant (His) thymidine kinase-1,EC 2.7.1.21,Thymidine k...	Canine	E. coli
	Thymidine kinase 1 (TK1) catalyzes the initial phosphorylation of thymidine in the salvage pathway synthesis of dTTP, an essential building block of DNA. TK1 is a cytosolic enzyme with its highest level during the S-phase of the cell cycle.
TMPJ-00769	TK1 Protein, Human, Recombinant (His) cytosolic,Thymidine kinase,TK1	Human	HEK293 Cells
	Thymidine kinase 1(TK1) belongs to the thymidine kinase family. It is located in the cytoplasm, and phosphorylated on Ser-13 in mitosis during post-translational modification. Two forms of this protein have been identified in animal cells, one in cytosol TK1 and one in mitochondria TK2. Thymidine kinases have a key function in the synthesis of DNA and thereby in cell division, as they are part of the unique reaction chain to introduce deoxythymidine into the DNA. Activity of the cytosolic enzyme...
TMPH-02403	JBP1 Protein, Leishmania infantum, Recombinant (His & V5) J-binding protein 1,Thymine dioxygenase JBP1,Thymidine	Leishmania infantum	E. coli
	JBP1 Protein, Leishmania infantum, Recombinant (His & V5) is expressed in E. coli expression system with N-10xHis-V5 tag. The predicted molecular weight is 53.4 kDa and the accession number is A4HU70.
TMPJ-00989	MTHFS Protein, Human, Recombinant (His) 5-formyltetrahydrofolate cyclo-ligase,10-methenyl-tetrahydro...	Human	E. coli
	5-formyltetrahydrofolate cyclo-ligase (MTHFS) belongs to the 5-formyltetrahydrofolate cyclo-ligase family. It is an enzyme that catalyzes the conversion of 5-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate, contributes to tetrahydrofolate metabolism. MTHFS helps regulate carbon flow through the folate-dependent one-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acids. An increased activity of the encoded protein can result in an increas...
TMPJ-00905	DTYMK Protein, Human, Recombinant (His) DTYMK,TMPK,dTMP kinase,Thymidylate kinase,CDC8,TYMK	Human	HEK293 Cells
	Thymidylate kinase (DTYMK) is a ubiquitous enzyme of about 25 kD which belongs to thymidylate kinase family. DTYMK is important in the dTTP synthesis pathway for DNA synthesis. It participated in the pyrimidine metabolism pathway and dTTP biosynthesis pathway. DTYMK catalyzes the conversion of dTMP to dTDP and catalyzes the phosphorylation of thymidine 5'-monophosphate (dTMP) to form thymidine 5'-diphosphate (dTDP) in the presence of ATP and magnesium. Structural and functional analyses suggest ...
TMPY-04542	CDK2 Protein, Human, Recombinant (His) CDKN2,cyclin-dependent kinase 2,p33(CDK2)	Human	Baculovirus Insect Cells
	CDK2 is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. Cdks (cyclin-dependent kinases) are heteromeric serine/threonine kinases that control progression through the cell cycle in concert with their regulatory subunits, the c...

重组蛋白

TK1 Potein, Canine, Recombinant (His)

Cat.No: TMPK-01386

Species: Canine

Expression System: E. coli

TK1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00769

Species: Human

Expression System: HEK293 Cells

JBP1 Protein, Leishmania infantum, Recombinant (His & V5)

Cat.No: TMPH-02403

Species: Leishmania infantum

Expression System: E. coli

MTHFS Protein, Human, Recombinant (His)

Cat.No: TMPJ-00989

Species: Human

Expression System: E. coli

DTYMK Protein, Human, Recombinant (His)

Cat.No: TMPJ-00905

Species: Human

Expression System: HEK293 Cells

CDK2 Protein, Human, Recombinant (His)

Cat.No: TMPY-04542

Species: Human

Expression System: Baculovirus Insect Cells

Cat. No.	Product Name	Target	Signaling Pathways
T36895	5-Fluorouracil-13C,15N2 5-Fluorouracil-13C,15N2
	5-Fluorouracil-13C,15N2 is intended for use as an internal standard for the quantification of 5-flurouracil by GC- or LC-MS. 5-Fluorouracil is a pyrimidine analog that irreversibly inhibits thymidylate synthase, blocking the synthesis of thymidine which is required for DNA synthesis. Intracellular metabolites of 5-fluorouracil exert cytotoxic effects by either inhibiting thymidylate synthetase, or through incorporation into RNA and DNA, ultimately initiating apoptosis.
TMID-0266	Stavudine-α,α,α,6-d4
	Stavudine-α,α,α,6-d4 是 Stavudine 的氘代化合物。Stavudine 的 CAS 号为 3056-17-5。Stavudine 是一种口服活性核苷逆转录酶抑制剂，还抑制线粒体 DNA 的复制，具有抗HIV-1和HIV-2的活性。它降低 NLRP3 炎症小体激活，调节淀粉样 β 自噬，诱导细胞凋亡。
TMID-0242	Capecitabine-d11
	Capecitabine-d11 是 Capecitabine 的氘代化合物。Capecitabine 的 CAS 号为 154361-50-9。Capecitabine 是一种可口服的前药，可由胸苷磷酸化酶催化转变为其活性代谢物 Fluorouracil。

同位素标记化合物

5-Fluorouracil-13C,15N2

Cat.No: T36895

Synonym: 5-Fluorouracil-13C,15N2

Stavudine-α,α,α,6-d4

Cat.No: TMID-0266

Capecitabine-d11

Cat.No: TMID-0242

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