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Search Results for " thiol-based "

Targets Recommended: Others

42

抑制剂 & 化合物

1

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T8483	Cysteine thiol probe Methyl (4-bromobenzoyl)-L-cysteinate	Others	Others
	Cysteine thiol probe (Methyl (4-bromobenzoyl)-L-cysteinate) 是基于硫醇的探针，旨在标记亲电子的天然产物。它能够结合基于烯酮，β-内酰胺和 β-内酯的亲电子代谢物。它具有理想药效团探针的每个特征，并具有发色团。
T18184	m-PEG3-SH M-PEG3-Thiol,2-(2-(2-Methoxyethoxy)Ethoxy)Ethanethiol	Others; PROTAC Linker	Others; PROTAC
	m-PEG3-SH (M-PEG3-Thiol) 是一种属于 PEG 类的 PROTAC linker，可用于 PROTAC 分子的合成。
T18832	Thiol-PEG-CH2COOH (MW 2000)	Others	Others
	Thiol-PEG-CH2COOH (MW 2000) is a PEG-based PROTAC linker utilized for synthesizing PROTACs[1].
T17398	Amine-PEG-thiol (MW 2000)	Others	Others
	Amine-PEG-thiol (MW 2000) is a PEG-based PROTAC linker employed in PROTAC synthesis[1].
T17076	Thiol-PEG3-phosphonic acid	Others	Others
	Thiol-PEG3-phosphonic acid is a PEG-based linker compound utilized in PROTAC synthesis[1].
T69327	E2072	Others	Others
	E2072 is a potent and selective thiol-based Glutamate Carboxypeptidase II (GCP-II) inhibitor.
T17399	Amine-PEG-thiol (MW 3400)	Others	Others
	Amine-PEG-thiol (MW 3400) is a polyethylene glycol (PEG)-based linker molecule containing an amine group and a thiol group. It serves as an essential component in the synthesis of proteolysis targeting chimeras (PROTACs)[1].
T12776	RT-AM	Others	Others
	RT-AM is a pro-drug real thiol. Real Thiol is a reversible reaction-based fluorescent probe.
T12776L	Real Thiol	Others	Others
	Real Thiol, a reversible reaction-based fluorescent probe, can quantitatively monitor the real-time glutathione dynamics in living cells.
T17400	Amine-PEG-thiol (MW 5000)	Others	Others
	Amine-PEG-thiol (MW 5000) is a polyethylene glycol (PEG) based PROTAC linker, primarily utilized for the synthesis of PROTACs[1].
T14716	Boc-Aminooxy-PEG3-thiol	Others	Others
	Boc-Aminooxy-PEG3-thiol is a polyethylene glycol (PEG)-based PROTAC linker, employed for the synthesis of PROTACs[1].
T18838	Thiol-PEG3-phosphonic acid ethyl ester	Others	Others
	Thiol-PEG3-phosphonic acid ethyl ester, a PEG-based linker, serves as a valuable component in the synthesis of PROTACs[1].
T18840	Thiol-PEG5-acid HS-PEG5-CH2CH2COOH	Others	Others
	Thiol-PEG5-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T18836	Thiol-PEG12-acid	Others	Others
	Thiol-PEG12-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T18844	Thiol-PEG9-alcohol HS-PEG9-OH	Others	Others
	Thiol-PEG9-alcohol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T40746	m-PEG7-thiol m-PEG7-thiol	Others	Others
	m-PEG7-thiol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T18110	m-PEG-thiol (MW 20000)	Others	Others
	m-PEG-thiol (MW 20000) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T15938	m-PEG8-thiol	Others	Others
	m-PEG8-thiol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T18842	Thiol-PEG6-acid	Others	Others
	Thiol-PEG6-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T17078	Thiol-PEG4-Boc Thiol-PEG4-t-butyl ester	Others	Others
	Thiol-PEG4-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T17079	Thiol-PEG6-alcohol HS-PEG6-OH	Others	Others
	Thiol-PEG6-alcohol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T40824	Thiol-C9-PEG4-acid Thiol-C9-PEG4-acid	Others	Others
	Thiol-C9-PEG4-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T18843	Thiol-PEG8-alcohol HS-PEG8-OH	Others	Others
	Thiol-PEG8-alcohol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T18144	m-PEG12-Thiol	Others	Others
	m-PEG12-Thiol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T17077	Thiol-PEG4-acid	Others	Others
	Thiol-PEG4-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T38756	Thiol-C10-amide-PEG8 Thiol-C10-amide-PEG8	Others	Others
	Thiol-C10-amide-PEG8 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T18602	VH032-thiol-C6-NH2 VHL Ligand-Linker Conjugates 14,E3 ligase Ligand-Linker Conjugates 29	Others	Others
	VH032-thiol-C6-NH2, also known as VHL Ligand-Linker Conjugates 14, is a synthesized compound that functions as an E3 ligase ligand-linker conjugate. This compound combines the VH032 based VHL ligand with a linker commonly utilized in PROTAC technology.
T18839	Thiol-PEG4-alcohol HS-PEG4-OH	Others	Others
	Thiol-PEG4-alcohol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T18841	Thiol-PEG5-alcohol HS-PEG5-OH	Others	Others
	Thiol-PEG5-alcohol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T15917	m-PEG6-thiol	Others	Others
	m-PEG6-thiol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T38703	Thiol-C9-PEG7 Thiol-C9-PEG7	Others	Others
	Thiol-C9-PEG7 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T38701	Thiol-C9-PEG4 Thiol-C9-PEG4	Others	Others
	Thiol-C9-PEG4 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T17075	Thiol-PEG3-Boc Thiol-PEG3-t-butyl ester	Others	Others
	Thiol-PEG3-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T17074	Thiol-PEG3-acid	Others	Others
	Thiol-PEG3-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T18835	Thiol-PEG10-alcohol HS-PEG10-OH	Others	Others
	Thiol-PEG10-alcohol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T18837	Thiol-PEG12-alcohol HS-PEG12-OH	Others	Others
	Thiol-PEG12-alcohol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T38702	Thiol-C9-PEG5 Thiol-C9-PEG5	Others	Others
	Thiol-C9-PEG5 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T17080	Thiol-PEG8-acid	Others	Others
	Thiol-PEG8-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T38821	Thiol-PEG2-t-butyl ester Thiol-PEG2-t-butyl ester	Others	Others
	Thiol-PEG2-t-butyl ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T18111	m-PEG-thiol (MW 5000)	Others	Others
	m-PEG-thiol (MW 5000) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T18108	m-PEG-thiol (MW 10000)	Others	Others
	m-PEG-thiol (MW 10000) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T18109	m-PEG-thiol (MW 2000)	Others	Others
	m-PEG-thiol (MW 2000) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

化合物

Cysteine thiol probe

Cat.No: T8483

Synonym: Methyl (4-bromobenzoyl)-L-cysteinate

Target: Others

Cat.No: T18184

Synonym: M-PEG3-Thiol,2-(2-(2-Methoxyethoxy)Ethoxy)Ethanethiol

Target: Others, PROTAC Linker

Thiol-PEG-CH2COOH (MW 2000)

Cat.No: T18832

Target: Others

Amine-PEG-thiol (MW 2000)

Cat.No: T17398

Target: Others

Thiol-PEG3-phosphonic acid

Cat.No: T17076

Target: Others

Cat.No: T69327

Target: Others

Amine-PEG-thiol (MW 3400)

Cat.No: T17399

Target: Others

Cat.No: T12776

Target: Others

Cat.No: T12776L

Target: Others

Amine-PEG-thiol (MW 5000)

Cat.No: T17400

Target: Others

Boc-Aminooxy-PEG3-thiol

Cat.No: T14716

Target: Others

Thiol-PEG3-phosphonic acid ethyl ester

Cat.No: T18838

Target: Others

Thiol-PEG5-acid

Cat.No: T18840

Synonym: HS-PEG5-CH2CH2COOH

Target: Others

Thiol-PEG12-acid

Cat.No: T18836

Target: Others

Thiol-PEG9-alcohol

Cat.No: T18844

Synonym: HS-PEG9-OH

Target: Others

Cat.No: T40746

Synonym: m-PEG7-thiol

Target: Others

m-PEG-thiol (MW 20000)

Cat.No: T18110

Target: Others

Cat.No: T15938

Target: Others

Thiol-PEG6-acid

Cat.No: T18842

Target: Others

Thiol-PEG4-Boc

Cat.No: T17078

Synonym: Thiol-PEG4-t-butyl ester

Target: Others

Thiol-PEG6-alcohol

Cat.No: T17079

Synonym: HS-PEG6-OH

Target: Others

Thiol-C9-PEG4-acid

Cat.No: T40824

Synonym: Thiol-C9-PEG4-acid

Target: Others

Thiol-PEG8-alcohol

Cat.No: T18843

Synonym: HS-PEG8-OH

Target: Others

m-PEG12-Thiol

Cat.No: T18144

Target: Others

Thiol-PEG4-acid

Cat.No: T17077

Target: Others

Thiol-C10-amide-PEG8

Cat.No: T38756

Synonym: Thiol-C10-amide-PEG8

Target: Others

VH032-thiol-C6-NH2

Cat.No: T18602

Synonym: VHL Ligand-Linker Conjugates 14,E3 ligase Ligand-Linker Conjugates 29

Target: Others

Thiol-PEG4-alcohol

Cat.No: T18839

Synonym: HS-PEG4-OH

Target: Others

Thiol-PEG5-alcohol

Cat.No: T18841

Synonym: HS-PEG5-OH

Target: Others

Cat.No: T15917

Target: Others

Thiol-C9-PEG7

Cat.No: T38703

Synonym: Thiol-C9-PEG7

Target: Others

Thiol-C9-PEG4

Cat.No: T38701

Synonym: Thiol-C9-PEG4

Target: Others

Thiol-PEG3-Boc

Cat.No: T17075

Synonym: Thiol-PEG3-t-butyl ester

Target: Others

Thiol-PEG3-acid

Cat.No: T17074

Target: Others

Thiol-PEG10-alcohol

Cat.No: T18835

Synonym: HS-PEG10-OH

Target: Others

Thiol-PEG12-alcohol

Cat.No: T18837

Synonym: HS-PEG12-OH

Target: Others

Thiol-C9-PEG5

Cat.No: T38702

Synonym: Thiol-C9-PEG5

Target: Others

Thiol-PEG8-acid

Cat.No: T17080

Target: Others

Thiol-PEG2-t-butyl ester

Cat.No: T38821

Synonym: Thiol-PEG2-t-butyl ester

Target: Others

m-PEG-thiol (MW 5000)

Cat.No: T18111

Target: Others

m-PEG-thiol (MW 10000)

Cat.No: T18108

Target: Others

m-PEG-thiol (MW 2000)

Cat.No: T18109

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-05058	TMX1 Protein, Human, Recombinant (mFc) thioredoxin-related transmembrane protein 1,PDIA11,TXNDC,TXN...	Human	HEK293 Cells
	As a thiol-based tumor suppressor, TMX1 increases mitochondrial ATP production and apoptosis progression. TMX1 is the first example of a topology-specific client protein redox catalyst acting both in the folding and in the degradative pathways.

重组蛋白

TMX1 Protein, Human, Recombinant (mFc)

Cat.No: TMPY-05058

Species: Human

Expression System: HEK293 Cells

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