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Search Results for " taste "

Targets Recommended: Taste receptor Antibacterial Parasite

20

抑制剂 & 化合物

12

天然产物

1

化合物库

6

重组蛋白

3

同位素标记化合物

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Cat. No.	Product Name
L9001	食品添加剂化合物库		425 compounds
	425种食品添加剂的集合

化合物库

食品添加剂化合物库

Cat.No: L9001

Compounds: 425

Cat. No.	Product Name	Target	Signaling Pathways
T40417	Ethylhydrocupreine hydrochloride Optochin hydrochloride,乙氢去甲奎宁盐酸盐；奥普托欣盐酸盐	Antibacterial; Parasite	Microbiology/Virology
	Ethylhydrocupreine hydrochloride (Optochin hydrochloride) 是奎宁的一种衍生物，具有抗菌作用，可抑制肺炎链球菌的活性。Ethylhydrocupreine hydrochloride 具有抗疟活性，对 Plasmodium falciparum 的IC50为 25.75 nM。Ethylhydrocupreine hydrochloride 是Gallus gallus2 受体 (ggTas2r1，ggTas2r2和ggTas2r7) 激动剂。
T1499	Dutasteride GG 745,Avodart,度他雄胺,GI 198745	Apoptosis; Reductase	Apoptosis; Endocrinology/Hormones; Metabolism
	Dutasteride (GI 198745) 是一种 5α 还原酶同工酶抑制剂，还可能因其结构域 DHT 相似对雄激素受体产生脱靶效应。
T11040	Dihydro Dutasteride	Others	Others
	Dihydro Dutasteride is a metabolite of Dutasteride. Dutasteride is an effective inhibitor of five α-reductase isozymes.
T10179	5β-Dutasteride	Others	Others
	5β-Dutasteride is the S configuration of Dutasteride. It is a potent inhibitor of both 5 alpha-reductase isozymes.
T28258L	Org 13011	5-HT Receptor	GPCR/G Protein; Neuroscience
	Org 13011 具有中枢神经系统活性，通过介导 5-HT 1A受体可诱导条件性味觉厌恶。
T34373	RO5166017 RO 5166017,RO-5166017	Others	Others
	RO5166017 是一种具有口服活性、高效性和选择性的痕量胺相关受体 1（TAAR1）激动剂，可用于研究条件性味觉厌恶额神经障碍。
TP2500	Cholecystokinin (26-33) free acid CCK (26-33) free acid	cholecystokinin	GPCR/G Protein
	Cholecystokinin (26-33) free acid 是胆囊收缩素 (CCK) 的一部分，是脊椎动物中枢神经系统中存在的 CCKB 型受体的高选择性配体，可诱导大鼠轻度味觉厌恶条件反射。
T22352	L-Gulose	Others; Endogenous Metabolite	Metabolism; Others
	L-Gulose 是一种合成维生素 C 的生物中间体，是一种 L-sorbosone 的呋喃糖形式，是L 己糖。
T35795	Lactisole na-PMP,2-(4-甲氧基苯氧基)丙酸	Taste receptor	Metabolism
	Lactisole (na-PMP) 是葡萄糖感应受体的抑制剂。
T69261	2-Pmp-PA	Others	Others
	2-Pmp-PA is a taste modulator that inhibits sweetness.
T38416	Adenosine 5'-succinate	Others	Others
	Adenosine 5'-succinate is a compound closely related to adenosine monophosphate (AMP) that demonstrates strong inhibitory properties against taste receptor activation of transducin caused by Denatonium benzoate.
T77989	Nα,Nα-Bis(carboxymethyl)-L-lysine
	Nα,Nα-Bis(carboxymethyl)-L-lysine作为bitter taste receptor 4的一种竞争性抑制剂，其IC50值为59 nM，适用于苦受体相关领域的科学研究。
T72009	N-Phenylthiourea	Others	Others
	N-Phenylthiourea is a tyrosinase inhibitor and building block. It increases the susceptibility of SK-MEL-188 melanoma cells in melanogenesis-inducing conditions to γ-radiation-induced cytotoxicity when used at a concentration of 0.01 μM. N-Phenylthiourea has been used as a precursor in the synthesis of compounds with antibacterial and antifungal activities. It has also been used as a genetic marker for taste because only some people detect it as a bitter taste.
T82315	GIV3727	Others	Others
	GIV3727 是 hTAS2R 苦味受体的拮抗剂，能够抑制糖精与安赛蜜对 hTAS2R31 的活化作用，有效改善食品、饮料和药品的苦味特性。
T82186	Homoglutathione
	Homoglutathione，一种在真核生物中普遍存在且不可或缺的三肽，主要功能与细胞的氧化还原调节相关，并具有味觉调节作用。
T72532	Ethylhydrocupreine Optochin	Others	Others
	Ethylhydrocupreine (Optochin) 是一种具有抗菌作用的奎宁衍生物，具有抗肺炎链球菌 (S. pneumoniae) 的活性。Ethylhydrocupreine 还具有抗Plasmodiumfalciparum 的抗疟活性，IC50为 25.75 nM。Ethylhydrocupreine 是一种Gallus gallus2 受体 (ggTas2r1，ggTas2r2和ggTas2r7) 激动剂。
T10560	P2X3 antagonist 34 BLU-5937
	P2X3 antagonist 34 是一种对P2X3同型三聚体受体具有高效性、选择性和口服活性的拮抗剂，其IC50值针对人类P2X3、大鼠P2X3及豚鼠P2X3分别为25 nM、92 nM和126 nM。相比之下，该化合物对人类、大鼠和豚鼠的P2X2/3异三聚体受体展现低活性。P2X3 antagonist 34 显著具有抗咳功效，同时不会影响味觉。
TP2515	Cyclo(L-Leu-L-Trp)	Others	Others
	Cyclo(L-Leu-L-Trp) is a diketopiperazine metabolite initially derived from Penicillium, exhibiting antibacterial (MICs = 125-1000 µg/ml) and antifungal activities (MICs = 8-64 µg/ml). It also demonstrates antioxidant properties by reducing the production of hydroxy radicals, as evidenced in an electron spin resonance (ESR) spectroscopy assay (IC50 = 1.8 µM). Additionally, Cyclo(L-Leu-L-Trp) has been identified as a bitter compound capable of quickly crossing rat taste cell membranes ex vivo at a...
T37476	Cyclo(L-Phe-L-Val)
	Cyclo(L-Phe-L-Val) is a metabolite of the sponge bacterium Pseudoalteromonas sp. NJ6-3-1 that can autoinduce production of antibacterial substances active against S. aureus when co-cultured at a low cell density. It induces neurite outgrowth and branching of chick cortical neurons in vitro when used at concentrations of 16 and 32 μM. It increases phosphorylation of the PI3K substrate Akt, and neurite outgrowth induced by cyclo(L-Phe-L-Val) can be blocked by the PI3K inhibitor LY294002 . Cyclo(L-...
T85207	1,2-Dipalmitoyl-3-Octanoyl-rac-glycerol 1,2-Palmitin-3-caprylin	Others	Others
	1,2-Dipalmitoyl-3-Octanoyl-rac-glycerol 是一种三酰基甘油，其结构特征在于 sn-1 和 sn-2 位置上连接有棕榈酸，在 sn-3 位置上连接有辛酸。棕榈酸，一种广泛存在于动植物体中的长链饱和脂肪酸，已知能够在小鼠颗粒细胞中诱导葡萄糖调节蛋白 78 (GRP78) 与 CCAAT/增强子结合蛋白同源蛋白 (CHOP) 的表达。辛酸，作为一种具有微弱腐臭味的油性液体，不仅应用于酯类香料与染料的制备中，还被认为是一种有效的震颤抑制剂。

化合物

Ethylhydrocupreine hydrochloride

Cat.No: T40417

Synonym: Optochin hydrochloride,乙氢去甲奎宁盐酸盐；奥普托欣盐酸盐

Target: Antibacterial, Parasite

Cat.No: T1499

Synonym: GG 745,Avodart,度他雄胺,GI 198745

Target: Apoptosis, Reductase

Dihydro Dutasteride

Cat.No: T11040

Target: Others

5β-Dutasteride

Cat.No: T10179

Target: Others

Cat.No: T28258L

Target: 5-HT Receptor

Cat.No: T34373

Synonym: RO 5166017,RO-5166017

Target: Others

Cholecystokinin (26-33) free acid

Cat.No: TP2500

Synonym: CCK (26-33) free acid

Target: cholecystokinin

Cat.No: T22352

Target: Others, Endogenous Metabolite

Cat.No: T35795

Synonym: na-PMP,2-(4-甲氧基苯氧基)丙酸

Target: Taste receptor

Cat.No: T69261

Target: Others

Adenosine 5'-succinate

Cat.No: T38416

Target: Others

Nα,Nα-Bis(carboxymethyl)-L-lysine

Cat.No: T77989

N-Phenylthiourea

Cat.No: T72009

Target: Others

Cat.No: T82315

Target: Others

Homoglutathione

Cat.No: T82186

Ethylhydrocupreine

Cat.No: T72532

Synonym: Optochin

Target: Others

P2X3 antagonist 34

Cat.No: T10560

Synonym: BLU-5937

Cyclo(L-Leu-L-Trp)

Cat.No: TP2515

Target: Others

Cyclo(L-Phe-L-Val)

Cat.No: T37476

1,2-Dipalmitoyl-3-Octanoyl-rac-glycerol

Cat.No: T85207

Synonym: 1,2-Palmitin-3-caprylin

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T78480	24-Epicastasterone 24-epi-Castasterone	Others	Others
	24-Epicastasterone (24-epi-Castasterone) 是从 Hydrodictyon reticulatum 中提取的天然油菜素内酯类化合物。
T40815	δ-Decalactone	Others	Others
	δ-Decalactone 存在于脱脂奶粉和水果中，具有甜味。
T2S1992	Perillartine Perilla sugar,Peryllartine,紫苏葶,DL-Perillartine	Others; Endogenous Metabolite	Metabolism; Others
	Perillartine (DL-Perillartine) 是甜味剂，能够激活味觉受体 1 型成员 2 。
TN7073	3-Feruloyl-4-caffeoylquinic acid	Others	Others
	3-Feruloyl-4-caffeoylquinic acid 是一种绿原酸异构体。绿原酸是相关的咖啡品质标志、味道和香气前体以及重要的生物活性化合物。
T2719	Succinic acid Asuccin,Amber acid,琥珀酸,1,2-Ethanedicarboxylic acid,Wormwood acid,Butanedioic acid,1,4-Butandioic Acid	Endogenous Metabolite	Metabolism
	Succinic acid (1,2-Ethanedicarboxylic acid) 是无氧代谢的发酵产物，也是三羧酸循环的中间产物。
T4838	(S)-Malic acid L-(-)-Malic acid,(S)-(-)-HYDROXYSUCCINIC ACID,(S)-2-Hydroxysuccinic acid,L-苹果酸	Others; Endogenous Metabolite	Metabolism; Others
	(S)-Malic acid ((S)-2-Hydroxysuccinic acid) 是天然存在的二羧酸，是水果酸甜味的来源，常用作食品添加剂。
TN3796	Dehydrobruceantinol	Others	Others
	Dehydrobruceantinol shows bitter taste and has antileukemic activity.
T66083	Dulcitol	Others	Others
	Dulcitol is a sugar alcohol and slightly sweet tastant for human taste cells.
T39614	Mogroside VI A	Others	Others
	Mogroside VI A is a saccharide compound, an isomer of Mogroside VI, that has been extracted from the Luo Han Guo plant. It possesses inherent sweetness properties. Mogroside VI A holds potential for application in sweetener and taste modifier studies.
TN1943	Momordicoside G	Others	Others
	Momordicosides K and L, the main bitter taste triterpene glycosides in Bitter melon; and bitter melon has been reported to have hypoglycemic, anti atherogenic and anti HIV activities.
TN4469	Lyoniresinol
	Lyoniresinol 是一种从 Tarenna attenuata 分离出来的木质素，具有清除自由基的活性（IC50为82.4μM）和 DPPH 的抗氧化活性，显示出抗黑色素生成活性。Lyoniresinol 有强烈的苦味，而其对映体(-)-Lyoniresinol 是无味的。
T82284	Glycyrrhizin-6′′-methylester
	Glycyrrhizin-6′′-methylester (compound 22) 是从甘草根中分离的一种甘草皂苷，能参与葡萄糖醛酸甲酯的生成，赋予其甜味和甘草特有风味，但不具苦味。该化合物的研究强调了糖苷锥结合葡萄糖醛酸的游离羧基在形成天然甜味和甘草味觉中的关键作用。

天然产物

24-Epicastasterone

Cat.No: T78480

Synonym: 24-epi-Castasterone

Target: Others

Cat.No: T40815

Target: Others

Cat.No: T2S1992

Synonym: Perilla sugar,Peryllartine,紫苏葶,DL-Perillartine

Target: Others, Endogenous Metabolite

3-Feruloyl-4-caffeoylquinic acid

Cat.No: TN7073

Target: Others

Cat.No: T2719

Synonym: Asuccin,Amber acid,琥珀酸,1,2-Ethanedicarboxylic acid,Wormwood acid,Butanedioic acid,1,4-Butandioic Acid

Target: Endogenous Metabolite

Cat.No: T4838

Synonym: L-(-)-Malic acid,(S)-(-)-HYDROXYSUCCINIC ACID,(S)-2-Hydroxysuccinic acid,L-苹果酸

Target: Others, Endogenous Metabolite

Dehydrobruceantinol

Cat.No: TN3796

Target: Others

Cat.No: T66083

Target: Others

Cat.No: T39614

Target: Others

Momordicoside G

Cat.No: TN1943

Target: Others

Cat.No: TN4469

Glycyrrhizin-6′′-methylester

Cat.No: T82284

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-02336	TAS2R10 Protein, Human, Recombinant (His & KSI) Taste receptor family B member 2,Taste rec...	Human	E. coli
	Gustducin-coupled strychnine receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. TAS2R10 Protein, Human, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight is 19.6 kDa and the accession number is Q9NYW0.
TMPH-03617	Miraculin Protein, Synsepalum dulcificum, Recombinant (His) Miraculin	Synsepalum dulcificum	P. pastoris (Yeast)
	Miraculin has the property of modifying a sour taste into a sweet taste. This alteration of taste perception persists for many minutes. Miraculin Protein, Synsepalum dulcificum, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 23.4 kDa and the accession number is P13087.
TMPY-01442	DMBT1 Protein, Human, Recombinant (His) GP340,deleted in malignant brain tumors 1,muclin	Human	HEK293 Cells
	Deleted in malignant brain tumors 1 protein, also known as glycoprotein 34, surfactant pulmonary-associated D-binding protein, DMBT1 and GP34, is a secreted protein which belongs to theDMBT1 family. DMBT1 contains 2CUB domains, 14SRCR domains and 1ZP domain. It is highly expressed in alveolar and macrophage tissues. In some macrophages, expression is detected on the membrane, and in other macrophages, it is strongly expressed in the phagosome/phagolysosome compartments. Defects in DMBT1 are invo...
TMPH-03616	Miraculin Protein, Synsepalum dulcificum, Recombinant (E. coli, His) Miraculin	Synsepalum dulcificum	E. coli
	Miraculin has the property of modifying a sour taste into a sweet taste. This alteration of taste perception persists for many minutes. Miraculin Protein, Synsepalum dulcificum, Recombinant (E. coli, His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 24.9 kDa and the accession number is P13087.
TMPY-02802	GNG13 Protein, Human, Recombinant (His) G(gamma)13,h2-35,G(γ)13,guanine nucleotide binding protein (...	Human	E. coli
	GNG13 is a subunit of heterotrimeric G proteins which consist of alpha, beta, and gamma subunits. Heterotrimeric G proteins are membrane-bound GTPases that are linked to 7-TM receptors. They function as signal transducers for the 7-transmembrane-helix G protein-coupled receptors. They are involved as a modulator or transducer in various transmembrane signaling systems. Each G protein is composed of an alpha-, beta- and gamma-subunit and is bound to GDP in the 'off' state. Ligand-receptor binding...
TMPY-01679	LCN1 Protein, Human, Recombinant (His) TLC,MGC71975,TP,VEGP,Lipocalin 1,PMFA	Human	HEK293 Cells
	Lipocalin-1, also known as Von Ebner gland protein, VEG protein, Tear Prealbumin, VEGP, Tear lipocalin, and LCN1 is a secreted protein that belongs to the calycin superfamily and Lipocalin family. Human Lipocalin-1 / VEGP was originally described as a major protein of human tear fluid, which was thought to be tear specific. Lipocalin-1 / VEGP is identical to lingual von Ebner's gland protein and is also produced in the prostate, nasal mucosa, and tracheal mucosa. Homologous proteins have been fo...

重组蛋白

TAS2R10 Protein, Human, Recombinant (His & KSI)

Cat.No: TMPH-02336

Species: Human

Expression System: E. coli

Miraculin Protein, Synsepalum dulcificum, Recombinant (His)

Cat.No: TMPH-03617

Species: Synsepalum dulcificum

Expression System: P. pastoris (Yeast)

DMBT1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01442

Species: Human

Expression System: HEK293 Cells

Miraculin Protein, Synsepalum dulcificum, Recombinant (E. coli, His)

Cat.No: TMPH-03616

Species: Synsepalum dulcificum

Expression System: E. coli

GNG13 Protein, Human, Recombinant (His)

Cat.No: TMPY-02802

Species: Human

Expression System: E. coli

LCN1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01679

Species: Human

Expression System: HEK293 Cells

Cat. No.	Product Name	Target	Signaling Pathways
TMID-0029	Succinic-2,2,3,3-d4 Acid
	Succinic-2,2,3,3-d4 Acid 是 Succinic Acid 的氘代化合物。Succinic Acid 的 CAS 号为 110-15-6。Succinic acid 是无氧代谢的发酵产物，也是三羧酸循环的中间产物。
TMIJ-0435	Octanoic Acid-d15
	Octanoic Acid-d15 是 Octanoic Acid 的氘代化合物。Octanoic Acid 的 CAS 号为 124-07-2。Caprylic acid天然存在于椰子和母乳中。它是一种油性液体，带有些许腐臭味，能用于酯类香料和染料的生产。
TMIJ-0205	Glycyrrhetinic acid-d3
	Glycyrrhetinic acid-d3 是 Glycyrrhetinic acid 的氘代化合物。Glycyrrhetinic acid 的 CAS 号为 1449-05-4。Glycyrrhetinic acid是一种饮食衍生的化合物，是NF-kB的抑制剂和蛋白酶体的激活剂，在多细胞生物中起到促进长寿和抗聚集因子的作用。它诱导细胞凋亡。

同位素标记化合物

Succinic-2,2,3,3-d4 Acid

Cat.No: TMID-0029

Octanoic Acid-d15

Cat.No: TMIJ-0435

Glycyrrhetinic acid-d3

Cat.No: TMIJ-0205

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