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Targets Recommended: Apoptosis Reactive Oxygen Species

99

抑制剂 & 化合物

5

天然产物

2

化合物库

5

同位素标记化合物

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Cat. No. Product Name
L9240 农药化合物库

270 compounds
270种农药相关化合物的独特集合,可用于高通量筛选和高内涵筛选;
L9830 抗帕金森病化合物库

857 compounds
857 种帕金森病相关的化合物集合,可用于高通量和高内涵筛选;

化合物库

农药化合物库
Cat.No: L9240
Compounds: 270
抗帕金森病化合物库
Cat.No: L9830
Compounds: 857
Cat. No. Product Name Target Signaling Pathways
T20543 Flurochloridone

氟咯草酮,R 40244,R-40244,R40244,EPA Pesticide Chemical Code 128401

Apoptosis; Reactive Oxygen Species Apoptosis; Immunology/Inflammation; Metabolism; NF-κB
Flurochloridone (R 40244) 是一种选择性除草剂。 Flurochloridone 诱导细胞凋亡并受线粒体功能障碍和氧化应激的调节。
T20573 Carbetamide

Legurame,卡草胺,EPA Pesticide Chemical Code 259200,Carbetamid,11,561 RP,Carbetamex,Caswell No. 159B

Others Others
Carbetamide (Caswell No. 159B) 是一种除草剂,在土壤中具有良好的流动性。
T41244 Triticonazole

Antifungal Microbiology/Virology
Triticonazole 是一种三唑类农药。它具有杀菌和干扰内分泌作用。
T20669 Bentazone

苯达松,BAS 351-07H,EPA Pesticide Chemical Code 275200

Others Others
Paicaotan is a heterocyclic herbicide. It can removal broadleaf weeds and sedge in the soybean field.
T39849 Propargite

Parasite Microbiology/Virology
Propropgite 通过诱导 DNA 损伤来诱导 β 细胞坏死。它诱导 MIN6 细胞死亡的 IC50为 1 μM.。它可用于杀死螨虫。
T29000 Tralomethrin

EPA Pesticide Chemical Code 121501,SAGA,HAG-107,HAG 107,Scout

Others Others
Tralomethrin is used as a pyrethroid insecticide. It modifies the gating kinetics of the sodium channels in neurons, increases the length of time the channel remains open after a stimulus, thereby depolarizing the neuron for a longer period of time. This leads to uncontrolled spasms, paralysis, and eventual death.
T24172 Iodofenphos

NSC-190998,EPA Pesticide Chemical Code 309700,Nuvanol N,NSC190998,NSC 190998

Others Others
Iodofenphos is an obsolete insecticide.
T23768 Azothoate

Caswell No. 206A,L 1058,L-1058,EPA Pesticide Chemical Code 206100,L1058

Others Others
Azothoate is an insecticide agent.
T8383 Cyclopentolate Hydrochloride

AChR Neuroscience
Cyclopentolate Hydrochloride 是一种阿托品样毒蕈碱受体拮抗剂,是眼科常用的抗毒蕈碱剂,对睫状肌毒蕈碱受体的 pKB 值为 7.8。
T29981 Amidochlor

Caswell No. 005B,EPA Pesticide Chemical Code 128001,MON 4620,MON 4621,Limit

Others Others
Amidochlor is a growth regulator.
T40656 Chlorobenzuron

Others Others
Chlorobenzuron 是一种有效的几丁质合成酶抑制剂,具有杀虫的活性,可以抑制幼虫发育和蛹化的作用。
T27794 λ-Cyhalothrin

lambda-Cyhalothrin,Karate,λ-氯氟氰菊酯,Icon

Sodium Channel; Parasite Membrane transporter/Ion channel; Microbiology/Virology
λ-Cyhalothrin (Icon) 是广谱的 II 型合成除虫菊酯杀虫剂,含有 α-氰基,用于防治多种害虫。它是一种钠通道神经毒素,靶向中枢神经系统中神经元膜。
T20539 Pirimiphos-methyl

R 33986,甲基嘧啶磷,AI3-27699,Caswell No. 334B,PP511,Actelic

AChE; Parasite Microbiology/Virology; Neuroscience
Pirimiphos-methyl (AI3-27699) 是一种速效有机磷杀虫剂和杀螨剂,对目标生物的乙酰胆碱酯酶有抑制作用。甲基嘧啶磷常用于农粮贮藏过程中甲虫、鼻甲虫、飞蛾和蝽蛄的防治。
T69692 BRD-K25923209

Others Others
BRD-K25923209 is a novel inhibitor of BAF transcriptional repression.
T14954 Chlorthal-dimethyl

Dimethyl tetrachloroterephthalate

Others Others
Chlorthal-dimethyl用作农药中间体。
T0528 4-Fluoroanisole

Others Others
4-Fluoroanisole 是医药、农药、液晶材料的中间体。
T7867 Flutriafol

NMDAR; Antifungal Microbiology/Virology; Neuroscience
Flutriafol 是一种三唑类广谱杀菌试剂。
T4384 Halofenozide

Others Others
Halofenozide 是一种新的昆虫生长调节剂 (IGR),具有苯甲酰肼结构,也是一种蜕皮激素 (ecdysteroid) 激动剂。可模拟天然昆虫蜕皮激素 20-羟基蜕皮激素的作用,
T0574 Diphenyl sulfide

二苯硫醚,Phenyl sulfide

Others Others
Diphenyl sulfide (Phenyl sulfide) 用作农药、医药、染料的中间体
T3493 Clofentezine

Bisclofentazin,Acaristop,Apollo,四螨嗪

Others Others
Clofentezine (Apollo) 是生长抑制剂,对螨虫具有显著的致死作用。
T7431 1,4-Dichlorobenzene

1,4-二氯苯,p-Dichlorobenzene,para-dichlorobenzene

Others Others
1,4-Dichlorobenzene (p-Dichlorobenzene) 是一种防蛀剂,也可用作生产颜料和杀虫剂及消毒剂等的中间体。
T0567 2-Amino-5-chlorobenzoic acid

Others; Amino Acids and Derivatives Metabolism; Others
2-Amino-5-chlorobenzoic acid 是杀虫剂 Chlordimeform 的代谢物。可用于制备缓解疾病的抗风湿药(DMARDs)。
T7440 p,p'-DDE

p,p'-dichlorodiphenyldichloroethylene,4,4'-DDE,Dichlorodiphenyldichloroethylene,2,2-双(4-氯苯基)-1,1-二氯乙烯

Androgen Receptor; Drug Metabolite Endocrinology/Hormones; Metabolism
p,p'-DDE (p,p'-dichlorodiphenyldichloroethylene) 是持久性 DDT 的主要代谢物。4,4'-DDE 是一种有效的雄激素受体拮抗剂,IC50=5 μM,Ki=3.5 μM。
T5116 Iprodione

Others; Reactive Oxygen Species; Antifungal Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB; Others
Iprodione 是一种二甲酰亚胺类的高度特异性杀菌剂,能通过产生自由氧自由基引起氧化损伤。
T4055 Etoxazole

Others Others
Etoxazole 是一种杀螨剂/杀虫剂,通过抑制几丁质生物合成来控制螨虫。用作农药检测的标准。
T20110 Ethylene thiourea

ETU,Imidazolidinethione,NCI C03372,NCIC03372,NCI-C03372,亚乙基硫脲

Others Others
Ethylene thiourea (NCIC03372) 是一种用于水果和蔬菜生产的农药。它还用作基于质子化学交换依赖性饱和转移的 MRI 研究的新型造影剂。
T16044 Methoprene

烯虫酯,ZR-515

Others Others
Methoprene (ZR-515) 是一种保幼激素模拟物和一种生物杀虫剂。Methoprene 作为昆虫生长调节剂,干扰昆虫的生命周期并阻止其成熟或繁殖。
T19739 Simazine

Tafazine,Aquazine,Radocon,Herbex,西玛津

Others Others
Simazine (Tafazine) 是三嗪类除草剂,普遍用于农业、盆栽植物和树木的生产。它具有植物毒性,但对土壤微生物和藻类毒性较低。
T0404 8-Hydroxyquinoline

Hydroxyquinoline,8-Quinolinol,羟基喹啉,Oxine,8-羟基喹啉,8-Oxychinolin

Others; Antibacterial; Antibiotic Microbiology/Virology; Others
8-Hydroxyquinoline (8-Quinolinol) 是单质子二齿螯合剂, 也是转录抑制剂,防腐剂,消毒剂和杀虫剂。
T5627 Methoxychlor

Others Others
Methoxychlor 是一种有机氯农药,被认为是一种内分泌干扰物,会影响不同细胞模型中的 Ca²⁺ 稳态和细胞活力。
T19735 Flucycloxuron

氟螨脲,(E)-flucycloxuron,Andalin

Others Others
Flucycloxuron ((E)-flucycloxuron) 是一种甲壳素合成抑制剂,用作杀虫剂。在昆虫模型中,该抑制剂已被证明会影响几种生殖事件,例如产卵前的持续时间。
T72049 4-N-Nonyloxyphenol

4-nonoxyphenol,p-Nonyloxyphenol

Others Others
4-N-Nonyloxyphenol (4-nonoxyphenol) 是一种基于高岭土纳米管的杂化光敏剂,是一种广泛使用的农药和内分泌干扰剂,可用于苯酚基农药的光降解。
T19859 Nicosulfuron

Milagro,Accent,Motivell,烟嘧磺隆

Others Others
Nicosulfuron (Milagro) 是一种磺酰脲类的选择性除草剂,常用作出苗后的除草剂,保护玉米作物免受杂草的侵害。它也能够降低乙酰乳酸合酶的活性。
T19084 1-Naphthyl acetate

AChE Neuroscience
1-Naphthyl acetate 是一种有吸引力的生色底物,用于检测红细胞乙酰胆碱酯酶的活性。它具有检测有机磷农药中毒的潜力。
T24179 Isocil

Hyvar,Herbicide 82

Others Others
Isocil is a pesticide.
T20249 Fenothiocarb

Phenothiocarb,KCO-3001,Panocon

Others Others
Fenothiocarb is an agent of pesticide.
T26125 Rovicurt

Permethrin-tetramethrin mixt.

Others Others
Rovicurt is use as a pesticide.
T25138 Barthrin

Others Others
Barthrin is used as an Experimental Pesticide.
T27137 Decarbofuran

Bayer 62863

Others Others
Decarbofuran is a carbamate pesticide.
T20938 o,p'-DDT

2,4'-DDT,ortho,para'-DDT

Others Others
O,P'-DDT, a chlorinated organic pesticide, has estrogenic activity.
T19809 Bensultap

Ruban,ZZ-Doricida,Bancol,Victenon

Others Others
Bensultap is an agricultural chemical typically used as a pesticide.
T23691 AI 3-25706

AI-3-25706,AI3-25706

Others Others
AI 3-25706 is a pesticide.
T25931 Pentachlorophenyl laurate

NSC-77542,Mystox LPL,NSC 77542,NSC77542

Others Others
Pentachlorophenyl laurate is used as a pesticide.
T20219 Bioresmethrin

Penick-1390,Bioresmetrina,Penick 1390,Penick1390

Others Others
Bioresmethrin is a pesticide of synthetic pyrethroid.
T20621 Isoprocarb

异丙威,Etrofolan,Mipcine,Hytox,Mipcin,Mipsin

Others Others
Isoprocarb is a metabolite of the pesticide.
T20826 Dioxabenzofos

Salithion

Others Others
Dioxabenzofos, a pesticide, could cause reversible ataxia in mice, chicken, and sheep.
T26671 Aspon

NSC2550,NSC-2550,NSC 2550

Others Others
Aspon is an organophosphate pesticide, it is used primarily on turf insects.
T20784 Bromofos

S-1942,Omexan,S 1942,Metabrom,Nexagan,Mexion

Others Others
Bromofos is a effective pesticide.
T25323 Dichlofenthion

NSC3130,NSC 3130,NSC-3130

Others Others
Dichlofenthion is a phosphorothioate which is primarily utilized as a pesticide and nematicide.
T24249 Karsil

Niagara-4562,Niagara 4562,Erlujixiancaoan,Niagara4562

Others Others
Karsil is an agricultural pesticide.

化合物

Flurochloridone
Cat.No: T20543
Synonym: 氟咯草酮,R 40244,R-40244,R40244,EPA Pesticide Chemical Code 128401
Target: Apoptosis, Reactive Oxygen Species
Carbetamide
Cat.No: T20573
Synonym: Legurame,卡草胺,EPA Pesticide Chemical Code 259200,Carbetamid,11,561 RP,Carbetamex,Caswell No. 159B
Target: Others
Triticonazole
Cat.No: T41244
Synonym:
Target: Antifungal
Bentazone
Cat.No: T20669
Synonym: 苯达松,BAS 351-07H,EPA Pesticide Chemical Code 275200
Target: Others
Propargite
Cat.No: T39849
Synonym:
Target: Parasite
Tralomethrin
Cat.No: T29000
Synonym: EPA Pesticide Chemical Code 121501,SAGA,HAG-107,HAG 107,Scout
Target: Others
Iodofenphos
Cat.No: T24172
Synonym: NSC-190998,EPA Pesticide Chemical Code 309700,Nuvanol N,NSC190998,NSC 190998
Target: Others
Azothoate
Cat.No: T23768
Synonym: Caswell No. 206A,L 1058,L-1058,EPA Pesticide Chemical Code 206100,L1058
Target: Others
Cyclopentolate Hydrochloride
Cat.No: T8383
Synonym:
Target: AChR
Amidochlor
Cat.No: T29981
Synonym: Caswell No. 005B,EPA Pesticide Chemical Code 128001,MON 4620,MON 4621,Limit
Target: Others
Chlorobenzuron
Cat.No: T40656
Synonym:
Target: Others
λ-Cyhalothrin
Cat.No: T27794
Synonym: lambda-Cyhalothrin,Karate,λ-氯氟氰菊酯,Icon
Target: Sodium Channel, Parasite
Pirimiphos-methyl
Cat.No: T20539
Synonym: R 33986,甲基嘧啶磷,AI3-27699,Caswell No. 334B,PP511,Actelic
Target: AChE, Parasite
BRD-K25923209
Cat.No: T69692
Synonym:
Target: Others
Chlorthal-dimethyl
Cat.No: T14954
Synonym: Dimethyl tetrachloroterephthalate
Target: Others
4-Fluoroanisole
Cat.No: T0528
Synonym:
Target: Others
Flutriafol
Cat.No: T7867
Synonym:
Target: NMDAR, Antifungal
Halofenozide
Cat.No: T4384
Synonym:
Target: Others
Diphenyl sulfide
Cat.No: T0574
Synonym: 二苯硫醚,Phenyl sulfide
Target: Others
Clofentezine
Cat.No: T3493
Synonym: Bisclofentazin,Acaristop,Apollo,四螨嗪
Target: Others
1,4-Dichlorobenzene
Cat.No: T7431
Synonym: 1,4-二氯苯,p-Dichlorobenzene,para-dichlorobenzene
Target: Others
2-Amino-5-chlorobenzoic acid
Cat.No: T0567
Synonym:
Target: Others, Amino Acids and Derivatives
p,p'-DDE
Cat.No: T7440
Synonym: p,p'-dichlorodiphenyldichloroethylene,4,4'-DDE,Dichlorodiphenyldichloroethylene,2,2-双(4-氯苯基)-1,1-二氯乙烯
Target: Androgen Receptor, Drug Metabolite
Iprodione
Cat.No: T5116
Synonym:
Target: Others, Reactive Oxygen Species, Antifungal
Etoxazole
Cat.No: T4055
Synonym:
Target: Others
Ethylene thiourea
Cat.No: T20110
Synonym: ETU,Imidazolidinethione,NCI C03372,NCIC03372,NCI-C03372,亚乙基硫脲
Target: Others
Methoprene
Cat.No: T16044
Synonym: 烯虫酯,ZR-515
Target: Others
Simazine
Cat.No: T19739
Synonym: Tafazine,Aquazine,Radocon,Herbex,西玛津
Target: Others
8-Hydroxyquinoline
Cat.No: T0404
Synonym: Hydroxyquinoline,8-Quinolinol,羟基喹啉,Oxine,8-羟基喹啉,8-Oxychinolin
Target: Others, Antibacterial, Antibiotic
Methoxychlor
Cat.No: T5627
Synonym:
Target: Others
Flucycloxuron
Cat.No: T19735
Synonym: 氟螨脲,(E)-flucycloxuron,Andalin
Target: Others
4-N-Nonyloxyphenol
Cat.No: T72049
Synonym: 4-nonoxyphenol,p-Nonyloxyphenol
Target: Others
Nicosulfuron
Cat.No: T19859
Synonym: Milagro,Accent,Motivell,烟嘧磺隆
Target: Others
1-Naphthyl acetate
Cat.No: T19084
Synonym:
Target: AChE
Isocil
Cat.No: T24179
Synonym: Hyvar,Herbicide 82
Target: Others
Fenothiocarb
Cat.No: T20249
Synonym: Phenothiocarb,KCO-3001,Panocon
Target: Others
Rovicurt
Cat.No: T26125
Synonym: Permethrin-tetramethrin mixt.
Target: Others
Barthrin
Cat.No: T25138
Synonym:
Target: Others
Decarbofuran
Cat.No: T27137
Synonym: Bayer 62863
Target: Others
o,p'-DDT
Cat.No: T20938
Synonym: 2,4'-DDT,ortho,para'-DDT
Target: Others
Bensultap
Cat.No: T19809
Synonym: Ruban,ZZ-Doricida,Bancol,Victenon
Target: Others
AI 3-25706
Cat.No: T23691
Synonym: AI-3-25706,AI3-25706
Target: Others
Pentachlorophenyl laurate
Cat.No: T25931
Synonym: NSC-77542,Mystox LPL,NSC 77542,NSC77542
Target: Others
Bioresmethrin
Cat.No: T20219
Synonym: Penick-1390,Bioresmetrina,Penick 1390,Penick1390
Target: Others
Isoprocarb
Cat.No: T20621
Synonym: 异丙威,Etrofolan,Mipcine,Hytox,Mipcin,Mipsin
Target: Others
Dioxabenzofos
Cat.No: T20826
Synonym: Salithion
Target: Others
Aspon
Cat.No: T26671
Synonym: NSC2550,NSC-2550,NSC 2550
Target: Others
Bromofos
Cat.No: T20784
Synonym: S-1942,Omexan,S 1942,Metabrom,Nexagan,Mexion
Target: Others
Dichlofenthion
Cat.No: T25323
Synonym: NSC3130,NSC 3130,NSC-3130
Target: Others
Karsil
Cat.No: T24249
Synonym: Niagara-4562,Niagara 4562,Erlujixiancaoan,Niagara4562
Target: Others
Cat. No. Product Name Target Signaling Pathways
TN2132 Quinizarin

1,4-Dihydroxyanthraquinone,1,4-二羟基蒽醌

Others; DNA/RNA Synthesis; Antifungal Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Others
Quinizarin (1,4-Dihydroxyanthraquinone) 是一种杀菌剂和杀虫剂,可抑制肿瘤细胞生长。
T0051 Urethane

Ethyl carbamate,Ethylurethane,Carbamic acid ethyl ester,氨基甲酸乙酯

Chloride channel; GABA Receptor; Antibacterial; GluR; NMDAR; AChR; Parasite Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience
Urethane (Ethylurethane) 是多种食品中发酵形成的副产物,是氨基甲酸的乙酯,具有抑制细菌、海胆卵、原生动物和植物组织生长的作用。
T40712 Diethyl fumarate

Others Others
Diethyl fumarate 是农药马拉硫磷的分解产物。 Diethyl fumarate 会在皮肤上引起非免疫性接触性荨麻疹。
T16042 Metaldehyde

BCL Apoptosis
Metaldehyde is used for snails and other gastropods pesticide against.
T36828 9(Z)-Tricosene

Others Others
(9Z)-Tricosene is a pheromone released by insects, including D. melanogaster, M. domestica (house fly), and A. mellifera L. (honey bee). In Drosophila, it induces aggregation behavior and is an oviposition guidance cue for females. Due to its aggregation-inducing activity, it is used as a bait pesticide to attract insects to traps. The mechanism of action in Drosophila is the activation of antennal basiconic Or7a receptors. It is also highly produced by honey bees during the waggle dance, which ...

天然产物

Quinizarin
Cat.No: TN2132
Synonym: 1,4-Dihydroxyanthraquinone,1,4-二羟基蒽醌
Target: Others, DNA/RNA Synthesis, Antifungal
Urethane
Cat.No: T0051
Synonym: Ethyl carbamate,Ethylurethane,Carbamic acid ethyl ester,氨基甲酸乙酯
Target: Chloride channel, GABA Receptor, Antibacterial, GluR, NMDAR, AChR, Parasite
Diethyl fumarate
Cat.No: T40712
Synonym:
Target: Others
Metaldehyde
Cat.No: T16042
Synonym:
Target: BCL
9(Z)-Tricosene
Cat.No: T36828
Synonym:
Target: Others
Cat. No. Product Name Target Signaling Pathways
TMIJ-0436 Metaldehyde-d16

Metaldehyde-d16 是 Metaldehyde 的氘代化合物。Metaldehyde 的 CAS 号为 108-62-3。
TMIJ-0346 1,4-Dichlorobenzene-d4

1,4-Dichlorobenzene-d4 是 1,4-Dichlorobenzene 的氘代化合物。1,4-Dichlorobenzene 的 CAS 号为 106-46-7。1,4-Dichlorobenzene 是一种防蛀剂,也可用作生产颜料和杀虫剂及消毒剂等的中间体。
TMIJ-0491 Simazine-d5

Simazine-d5 是 Simazine 的氘代化合物。Simazine 的 CAS 号为 122-34-9。Simazine 是三嗪类除草剂,普遍用于农业、盆栽植物和树木的生产。它具有植物毒性,但对土壤微生物和藻类毒性较低。
TMIJ-0464 trans-Cypermethrin-d6 (dimethyl-d6)

trans-Cypermethrin-d6 (dimethyl-d6) 是 trans-Cypermethrin 的氘代化合物。trans-Cypermethrin 的 CAS 号为 67375-30-8。alpha-Cypermethrin 是一种合成拟除虫菊酯杀虫剂,用于大规模商业农业应用。
TMIJ-0419 Ethylene thiourea-d4

Ethylene thiourea-d4 是 Ethylene thiourea 的氘代化合物。Ethylene thiourea 的 CAS 号为 96-45-7。Ethylene thiourea 是一种用于水果和蔬菜生产的农药。它还用作基于质子化学交换依赖性饱和转移的 MRI 研究的新型造影剂。

同位素标记化合物

Metaldehyde-d16
Cat.No: TMIJ-0436
Synonym:
Target:
1,4-Dichlorobenzene-d4
Cat.No: TMIJ-0346
Synonym:
Target:
Simazine-d5
Cat.No: TMIJ-0491
Synonym:
Target:
trans-Cypermethrin-d6 (dimethyl-d6)
Cat.No: TMIJ-0464
Synonym:
Target:
Ethylene thiourea-d4
Cat.No: TMIJ-0419
Synonym:
Target:
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