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Cat. No. | Product Name | Target | Signaling Pathways |
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TP2280 |
ovalbumin (324-338) [Gallus gallus]/[Coturnix coturnix]
|
Others | Others |
Ovalbumin is the main protein found in egg white, making up 60-65% of the total protein. Ovalbumin is an important protein in several different areas of research, including general studies of protein structure and properties. Ovalbumin is used for studies | |||
T80099 |
Ovalbumin (154-159)
|
Angiotensin-converting Enzyme (ACE) | Metabolism |
Ovalbumin (154-159)为卵清蛋白片段,同时作为一种有效的血管紧张素转换酶 (ACE) 抑制剂,适用于高血压研究。 | |||
T4657 |
WHI-P97
4-(3',5'-二溴-4-羟基苯基)氨基-6,7-二甲氧基喹唑啉 |
JAK | Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells |
WHI-P97 是一种选择性 JAK-3抑制剂,可用于预防过敏性哮喘的研究。 | |||
T33647L |
Nesosteine Lithium
Nesosteine Lithium(84233-61-4 Free baes) |
Others | Others |
Nesosteine Lithium 是一种新型的粘液调节剂,对豚鼠 Herxheimer 微休克具有抑制作用且抑制卵清蛋白诱导的组胺在致敏动物气管中的释放。Nesosteine Lithium 能够保护致敏动物免受卵清蛋白诱导的支气管痉挛但对组胺和乙酰胆碱诱导的支气管痉挛无效。 | |||
TP1591L |
OVA G4 peptide acetate(148274-82-2 free base)
SIIGFEKL acetate |
Others | Others |
OVA G4 peptide acetate(148274-82-2 free base) (SIIGFEKL acetate) 是激动剂卵清蛋白 (OVA) 肽 (257-264) SIINFEKL 的变体。 OVA 肽是卵清蛋白的 I 类 (Kb) 限制性肽表位,由 I 类 MHC(主要组织相容性复合物)分子 H-2Kb(小鼠 MHC I 类基因)呈递。 | |||
TP1327L |
AOVA Peptide 257-264 2TFA
OVA Peptide 257-264 2TFA (138831-86-4 free base),OVA Peptide 257-264 2TFA 1262751-08-5(TFA-2TFA) |
Others | Others |
OVA Peptide 257-264 2TFA (138831-86-4 free base) 是 OVA 的 I 类 (Kb) 限制性肽表位,OVA 是卵清蛋白的八聚体肽,由 I 类 MHC 分子 H-2Kb 呈递。 | |||
TP1591 |
OVA G4 peptide
|
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G4 peptide (SIIGFEKL) is a variant of the agonist ovalbumin (OVA) peptide (257-264), SIINFEKL. OVA Peptide is a class I (Kb)-restricted peptide epitope of ovalbumin presented by the class I MHC (major histocompatibility complex) molecule, H-2Kb (class I genes of the mouse MHC). | |||
TP1652 |
OVA G4 peptide TFA (148274-82-2 free base)
OVA G4 peptide TFA |
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OVA G4 peptide TFA is an TFA salt form of OVA G4 peptide. G4 peptide (SIIGFEKL) is a variant of the agonist ovalbumin (OVA) peptide (257-264), SIINFEKL. OVA Peptide is a class I (Kb)-restricted peptide epitope of ovalbumin presented by the class I MHC (major histocompatibility complex) molecule, H-2Kb (class I genes of the mouse MHC). | |||
T39005 |
OVA (55-62)
|
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OVA 55-62 is a truncated peptide derived from the ovalbumin (OVA) antigen, specifically designed to bind to the H2-Kb mouse major histocompatibility complex (MHC) class I molecule. | |||
T37722 |
Diprovocim-1
|
Others | Others |
Diprovocim-1 is an agonist of the toll-like receptor 1/2 heterodimer.1It induces TNF-α release in THP-1 cells (EC50= 110 pM), an effect that can be inhibited by anti-TLR1 or anti-TLR2 antibodies. Diprovocim-1 (10 mg/kg) increases the production of ovalbumin-specific IgG1 in wild-type, but notTLR2-/-, mice sensitized to ovalbumin.2It also enhances anti-PD-L1 antibody-induced activation of cytotoxic T lymphocytes, reduction of tumor growth, and increases in survival in a B16/F10 murine melanoma mo... | |||
TP1327 |
OVA Peptide(257-264) TFA
OVA Peptide (257-264) TFA |
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OVA Peptide (257-264) TFA, an octameric peptide epitope from ovalbumin, is presented by the class I MHC molecule, H-2Kb, showcasing a class I (Kb)-restricted profile. | |||
T7619 |
OVA Peptide(257-264)
OVA Peptide 257-264,OVA Peptide 257-264 (2TFA) |
Others | Others |
OVA Peptide(257-264) 是 OVA 的 I 类 (Kb)-限制性肽表位,其中OVA 是一种来自卵清蛋白的八聚体肽,由 I 类 MHC 分子 H-2Kb 所呈递。 | |||
T78000 |
OVA Peptide (323-339)
|
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OVA Peptide (323-339) 是卵清蛋白(OVA)的T和B细胞表位,对BALB/c小鼠的瞬时超敏反应生成与发展至关重要。 | |||
T81589 |
OVA-A2 Peptide
SAINFEKL, OVA (257-264) Variant |
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OVA-A2 Peptide(SAINFEKL, OVA (257-264) Variant)是具备生物活性的A2肽(SAINFEKL)变体,具有抗原特性。 | |||
TP1339 |
OVA Peptide 323-339
|
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OVA Peptide (323-339) represents a T and B cell epitope of Ovalbumin (Ova), which play an important role in the development and development of immediate hypersensitivity in BALB/c mice. | |||
T38350 |
TAS 205
|
Others | Others |
TAS 205 is an inhibitor of hematopoietic prostaglandin D synthase (H-PGDS; IC50= 55.8 nM).1It is selective for H-PGDS over lipocalin-type PGDS (L-PGDS) at 100 μM, as well as over enzyme and receptor panels at 10 μM. TAS 205 inhibits production of prostaglandin D2induced by A23187 in KU812 human and RBL-2H3 rat basophils with IC50values of 78.3 and 181.3 nM, respectively. It inhibits ovalbumin-induced nasal lavage fluid eosinophil infiltration and late-phase nasal obstruction in an ovalbumin-sens... | |||
T81590 |
OVA peptide
|
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OVA peptide,主要源于鸡蛋清,作为I类MHC(主要组织相容性复合体)分子H-2Kb(小鼠MHC的I类基因)所呈递的特定卵白蛋白Kb限制性表位。在过敏性研究领域,OVA peptide具有广泛应用。 | |||
T37604 |
ITK inhibitor
|
Others | Others |
Interleukin-2-inducible T cell kinase (ITK) is a non-receptor tyrosine kinase expressed in T cells, NKT cells and mast cells which plays a crucial role in regulating the T cell receptor (TCR), CD28, CD2, chemokine receptor CXCR4, and FcepsilonR-mediated signaling pathways. ITK inhibitors can be used for the treatment of inflammation and immune-mediated disorders. ITK inhibitor (N-[5-[[3-[(4-Acetylpiperazin-1-yl)carbonyl]-4-methyl-6-methoxy-phenyl]thio]thiazol-2-yl]-4-(N-1,2-dimethylpropylaminome... |
Cat. No. | Product Name | Target | Signaling Pathways |
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T12500 |
Platycoside E
Platycodin E,桔梗苷E |
Others | Others |
Platycoside E (Platycodin E) 是一种桔梗皂苷元型皂苷,从桔梗的根中分离获得,能够促进 ovalbumin 免疫小鼠中血清 OVA 特异性IgG2a 和IgG2b 抗体的产生。它具有溶血活性和佐剂潜力。 | |||
T64744 |
Ovalbumins
|
Endogenous Metabolite | Metabolism |
Ovalbumins 是蛋清中的主要蛋白质。Ovalbumins 具有多种生物活性,如降压、抗菌、抗癌、抗氧化和免疫调节活性。Ovalbumins 是雌激素或孕酮处理的输卵管中合成的丰富的蛋白质。Ovalbumins 通常用作研究激素控制该组织中基因表达的标志物。 | |||
TMA1570 |
Sappanone A
|
NF-κB; Nrf2 | Immunology/Inflammation; NF-κB |
Sappanone A 是一种高异黄烷酮,通过调节 Nrf2 和 NF-κB 表现出抗炎作用。Sappanone A 可以减轻卵清蛋白引起的哮喘中的过敏性气道炎症。 | |||
T4S2164 |
Narirutin
Naringenin-7-O-rutinoside,Isonaringin,芸香柚皮苷,柚皮芸香苷 |
Others; Antibacterial | Microbiology/Virology; Others |
Narirutin (Naringenin-7-O-rutinoside) 是从Citrus unshiu 中分离的活性成分之一,具有抗氧化和抗炎活性。它是一种具有抗结核效力的shikimate 激酶抑制剂。 | |||
TN2974 |
3-O-Methylquercetin tetraacetate
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IL Receptor; TNF; PDE | Apoptosis; Immunology/Inflammation; Metabolism |
Quercetin 3-O-methyl ether is a potent phosphodiesterase (PDE)3/4 inhibitor, it has potential for treating asthma against ovalbumin-induced airway hyperresponsiveness. | |||
TN4819 | (-)-Praeruptorin A | ATPase; IL Receptor; Calcium Channel; P-gp | Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Neuroscience |
(-)-Praeruptorin A has anti-inflammatory, anti-contractile and anti-hyperplasia activities, it exerts distinct relaxant effects on isolated rat aorta rings dependent on endothelium and nitric oxide synthesis;it also can significantly suppress airway inflammation and airway remodeling induced by ovalbumin challenge, and is a potential candidate for the treatment of asthma. (-)-Praeruptorin A resensitizes Pgp-mediated MDR (Pgp-MDR) cancer cells to cancer drugs. |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02542 |
Serpin B6b Protein, Mouse, Recombinant (His)
Spi12,NK13,ovalbumin |
Mouse | Baculovirus Insect Cells |
Serpin B6b Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 44 kDa and the accession number is O08804. | |||
TMPY-01551 |
Serpin B8 Protein, Mouse, Recombinant (His)
CAP-2,serpin peptidase inhibitor, clade B (ovalbumin |
Mouse | Baculovirus Insect Cells |
Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner.Mouse SerpinB8, also known as Cytoplasmic antiproteinase 2, Peptidase inhibitor 8, SerpinB8, PI-8, SERPINB8 and CAP2, is a member of the Serpin superfamily. SERPINB8 was broadly expressed. In normal... | |||
TMPY-01718 |
Serpin B12 Protein, Mouse, Recombinant (His)
2300003F07Rik,4833409F13Rik,serpin peptidase inhibitor, clad... |
Mouse | Baculovirus Insect Cells |
Serpins are the largest and most diverse family of serine protease inhibitors which are involved in some fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner. Most serpins are secreted and attain physiologic concentrations in the blood and extracellular fluids. Mouse SerpinB12 is a cytoplasm protein that belongs to the serpin family and Ov-serpin subfamily. It ... | |||
TMPY-01589 |
Serpin B10 Protein, Mouse, Recombinant (His)
Serpinb10-ps,serpin peptidase inhibitor, clade B (ovalbu... |
Mouse | Baculovirus Insect Cells |
Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner. Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was originally coined because many serpins inhi... | |||
TMPY-02210 |
Serpin B9 Protein, Human, Recombinant (His)
CAP-3,PI-9,CAP3,PI9,serpin peptidase inhibitor, clade B ( |
Human | Baculovirus Insect Cells |
SerpinB9, also known as Cytoplasmic antiproteinase 3, CAP-3, Peptidase inhibitor 9, SERPINB9 and PI-9, is a cytoplasm protein that belongs to the serpin family and Ov-serpin subfamily. Serpin-B9 ( CAP-3 / PI-9 ) is the only known human intracellular inhibitor of granzyme B (GrB), the effector molecule in immunity against cytomegalovirus (CMV) and in renal allograft rejection. Serpin-B9 and SPI-6 expression in immune-privileged cells, APCs, and CTLs protect these cells against the actions of gran... | |||
TMPJ-00928 |
Serpin B3 Protein, Human, Recombinant (C-His)
SCCA1,serpin peptidase inhibitor, clade B (ovalbumin |
Human | HEK293 Cells |
Serpin B3 Protein, Human, Recombinant (C-His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 41-50 KDa and the accession number is P29508. | |||
TMPJ-00929 |
Serpin B3 Protein, Human, Recombinant (N-His)
SCCA-1,Serpin B3,serine (or cysteine) proteinase inhibitor, ... |
Human | E. coli |
Serpin B3 Protein, Human, Recombinant (N-His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 40-55 KDa and the accession number is P29508. | |||
TMPY-02425 |
Serpin B4, Protein, Human, Recombinant (His)
SCCA-2,LEUPIN,SCCA1,serpin peptidase inhibitor, clade B ( |
Human | Baculovirus Insect Cells |
Overexpression of SERPINB4 in tumor cells inhibited recombinant GrM-induced as well as NK cell-mediated cell death and this inhibition depended on the reactive center loop of the serpin. | |||
TMPY-01711 |
Serpin B2 Protein, Human, Recombinant (GST)
PAI,serpin peptidase inhibitor, clade B (ovalbumin)... |
Human | Baculovirus Insect Cells |
Serpins are the largest and most diverse family of serine protease inhibitors which are involved in some fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner.SerpinB2, also known as Plasminogen activator inhibitor 2, Placental plasminogen activator inhibitor, Monocyte Arg-serpin, Urokinase inhibitor and PAI2, is a cytoplasm protein that belongs to the serpin fa... | |||
TMPY-02712 |
Serpin B3 Protein, Human, Recombinant (His)
T4-A,HsT1196,serpin peptidase inhibitor, clade B (ovalbu... |
Human | Baculovirus Insect Cells |
SERPINB3, also known as SCCA-1, belongs to the serpin family. Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was originally coined because many serpins inhibit chymotrypsin-like serine proteases. SERPINB3 is expressed in some hepatocellular carcinoma (at protein level). Its expression is closely related to cellular differentiation in both normal and malignant squamous cells. It seems to also be... | |||
TMPY-02128 |
Serpin B1 Protein, Human, Recombinant (His)
HEL57,serpin peptidase inhibitor, clade B (ovalbumin |
Human | Baculovirus Insect Cells |
SerpinB1 is an endogenous inhibitor of serine proteases recognized for its anti-inflammatory and host-protective properties. Serum SerpinB1 levels are elevated in patients with type 2 diabetes compared with that in healthy subjects and are negatively correlated with serum LDL-C. serpinB1 as an endogenous protein that can potentially be harnessed to enhance functional beta cell mass in patients with diabetes. | |||
TMPY-02242 |
Serpin B6 Protein, Human, Recombinant (His)
DKFZp686I04222,PTI,SPI3,PI-6,RP1-90J20.6,serpin peptidase in... |
Human | Baculovirus Insect Cells |
SerpinB6, also known as Cytoplasmic antiproteinase, Peptidase inhibitor 6, Placental thrombin inhibitor, SERPINB6 and PI-6, is a cytoplasm protein that belongs to the serpin family and Ov-serpin subfamily. SerpinB6 / PI-6 is an inhibitor of cathepsin G, kallikrein-8 and thrombin. It may play an important role in the inner ear in the protection against leakage of lysosomal content during stress and loss of this protection results in cell death and sensorineural hearing loss. SerpinB6 / PI-6 is ex... | |||
TMPK-01413 |
H-2K (b) &B2M&OVA (SIINFEKL) Monomer Protein, Mouse, MHC (His & Avi)
H-2K,OVA,MHC,H2-K1 |
Mouse | HEK293 Cells |
Ovalbumin (OVA) has been historically a popular source of such antigens, since OVA can induce both humoral and cellular immune responses based on well-characterised peptide epitopes. The OVA257-264 octapeptide was one of the frst OVA epitopes to be characterised, it has an amino acid sequence SIINFEKL, which is recognised by cytotoxic T lymphocytes. SIINFEKL forms fbrillar assemblies similar to other peptide hydrogels. Te immunoactive properties of this peptide can therefore be related to its se... | |||
TMPY-01855 |
Serpin A10 Protein, Mouse, Recombinant (His)
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase,... |
Mouse | HEK293 Cells |
Protein Z-dependent protease inhibitor, also known as PZ-dependent protease inhibitor, SERPINA1 and ZPI, is a secreted protein that belongs to the serpin family. It is expressed by the liver and secreted in plasma. SERPINA1 / Serpin-A1 inhibits factor Xa activity in the presence of protein Z, calcium and phospholipid. Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was originally coined because ... | |||
TMPY-01893 |
Serpin A12 Protein, Human, Recombinant (His)
OL-64,serpin peptidase inhibitor, clade A (α-1 antiproteinas... |
Human | HEK293 Cells |
Serpins are the largest and most diverse family of protease inhibitors. Most serpins control proteolytic cascades, certain serpins do not inhibit enzymes, but instead perform diverse functions such as storage (ovalbumin, in egg white), hormone carriage proteins (thyroxine-binding globulin, cortisol-binding globulin) and tumor suppressor genes (maspin). Most inhibitory serpins target chymotrypsin-like serine proteases. These enzymes are defined by the presence of a nucleophilic serine residue in ... |
Cat. No. | Product Name | Target | Signaling Pathways |
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T71329 |
Theophylline-d6
|
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Theophylline-d6 is intended for use as an internal standard for the quantification of theophylline by GC- or LC-MS. Theophylline is an inhibitor of phosphodiesterase. It is also an adenosine A1 and A2 receptor antagonist. Theophylline induces relaxation of isolated cat bronchial smooth muscle segments precontracted with acetylcholine. It inhibits ovalbumin-induced increases in bronchoalveolar lavage fluid (BALF) eosinophil infiltration in an ovalbumin-sensitized mouse model of allergic asthma. F... |