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Targets Recommended: AChR

42

抑制剂 & 化合物

7

天然产物

29

重组蛋白

4

同位素标记化合物

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Cat. No. Product Name Target Signaling Pathways
T22371 Mivacurium dichloride

米库氯铵,Mivacurium chloride,二氯美维库铵

AChR Neuroscience
Mivacurium dichloride (Mivacurium chloride) 是苄基异喹啉衍生物,可与 nAChR 偶联,以减少或抑制乙酰胆碱对肌肉细胞末端盘的去极化作用。它也是非去极化短效的神经肌肉阻滞剂和骨骼肌松弛剂。
T21550 Blebbistatin

(±)-Blebbistatin

ATPase; Myosin Cytoskeletal Signaling; Membrane transporter/Ion channel
Blebbistatin ((±)-Blebbistatin) 是一种选择性的非肌肉肌球蛋白 II 抑制剂,可促进角膜内皮细胞 (CEC) 的定向迁移并加速伤口愈合,并保留了细胞连接的完整性和屏障功能。Blebbistatin 是 MYH9 抑制剂。
T6038 (-)-Blebbistatin

(S)-(-)-Blebbistatin

ATPase; Myosin Cytoskeletal Signaling; Membrane transporter/Ion channel
(-)-Blebbistatin ((S)-(-)-Blebbistatin) 是 blebbistatin 的 S 对映异构体。(-)-Blebbistatin 是一种肌球蛋白 II 抑制剂 (IC50=0.5-5 μM),具有有效性和选择性。(-)-Blebbistatin 可以用于抑制心肌肌球蛋白、非肌肉肌球蛋白II和骨骼肌肌球蛋白。
T0156 Rocuronium bromide

ORG 9426,罗库溴铵,ORG 9426 (Bromide)

AChR Neuroscience
Rocuronium bromide (ORG 9426) 是一种氨基甾体类的、非去极化的神经肌肉受体抑制剂,也是一种肌肉松弛剂。
T24906L Tuna AI acetate

Angiotensin-converting Enzyme (ACE) Metabolism
Tuna AI acetate 是一种源自金枪鱼肌肉的非竞争性血管紧张素转换酶 (ACE) 抑制剂。
T12481 Pipecuronium bromide

RGH-1106

AChR Neuroscience
Pipecuronium bromide (RGH-1106)是一种具有选择性和有效性的 nAChR 拮抗剂,也可当作一种非去极化甾体神经肌肉阻滞剂,可使肌肉松弛,常与抗生素一起使用。
T0715 Chlormezanone

Trancopal,氯美扎酮,芬那露

Others; GABA Receptor Membrane transporter/Ion channel; Neuroscience; Others
Chlormezanone (Trancopal) 是一种非苯二氮卓类药物,用于治疗焦虑症和肌肉痉挛。
T1594 Vecuronium bromide

ORG NC 45,维库溴铵

AChR Neuroscience
Vecuronium bromide (ORG NC 45) 是一种合成的中效单季铵盐类固醇和非去极化神经肌肉阻滞剂,具有肌肉松弛活性。
T3194 Ro 46-2005

Endothelin Receptor GPCR/G Protein
Ro 46-2005是新型非肽类内皮素拮抗剂,能够抑制人血管平滑肌细胞(ETA 受体)(IC50:220 nM)。
T0888 Felbinac

Dapson,4-联苯乙酸,4-Biphenylacetic acid

COX Immunology/Inflammation; Neuroscience
Felbinac (Dapson) 是非甾体抗炎药,可用于肌肉炎症和关节炎的研究。
T0939 Phenytoin

苯妥英,Diphenylhydantoin,5,5-Diphenylhydantoin

Virus Protease; Sodium Channel Membrane transporter/Ion channel; Microbiology/Virology
Phenytoin (5,5-Diphenylhydantoin) 是一种有效的电压门控钠离子通道阻滞剂,可减少小鼠乳腺肿瘤的生长和转移,具有抗癫痫活性。
T71356 Lanperisone HCl

NK 433

Apoptosis Apoptosis
Lanperisone HCl (NK 433) 是新型可口服的中枢作用肌肉松弛剂,具有抗癌活性,抑制单突触和多突触反射电位。Lanperisone HCl 通过在细胞周期和翻译独立性中诱导非凋亡细胞死亡而起作用。
T2408 Ostarine

MK-2866,GTX-024,Enobosarm

Androgen Receptor Endocrinology/Hormones
Ostarine (MK-2866) 是一种具有合成代谢活性的非甾体药物。选择性雄激素受体调节剂 (SARM) GTx-024 旨在像睾酮一样发挥作用,从而促进和/或维持性欲、生育能力、前列腺生长以及肌肉生长和力量。模仿睾酮的作用,这种药物可以增加瘦体重,从而改善癌症恶病质高代谢状态下的肌肉萎缩。
T1158 Phenoxybenzamine hydrochloride

苯氧苯札明,NCI-c01661,NSC 37448,盐酸酚苄明,Phenoxybenzamine HCl

CaMK; Adrenergic Receptor GPCR/G Protein; Neuroscience
Phenoxybenzamine hydrochloride (NCI-c01661) 是一种选择性的 α-adrenoceptor 和 calmodulin 的抑制剂,是常用的抗高血压药。
TP1115 L-Asparaginase

L-​ASNase

Others Others
L-Asparaginase (L-​ASNase) 是催化 L-天冬酰胺转化的水解酶,从血浆中去除 L-天冬酰胺,导致 RNA 和 DNA 合成抑制,随后引起细胞凋亡。它用于急性淋巴细胞白血病的研究。
T16344 NS-2028

Others; Guanylate cyclase GPCR/G Protein; Others
NS-2028 是一种高度选择性的可溶性鸟苷酸环化酶抑制剂。它抑制 3-吗啉代-sydnonimine 在人培养的脐静脉内皮细胞中形成环状 GMP,IC50为30mM。它抑制小鼠小脑匀浆和神经元 NO 合酶中的可溶性鸟苷酸环化酶活性,IC50分别为 17 和 20 mM。它可降低血管内皮生长因子诱导的血管生成和通透性。
T29846 Alcuronium free base

Alcuronium,Alcuronum,Diallylnortoxiferine,Alcuronium kation,Alloferine

Others Others
Alcuronium free base is a non-depolarizing skeletal muscle relaxant similar to Tubocurarine. It is used as an anesthesia adjuvant.
T25636 Laudexium

Laudexium ion,Laudexium cation

Others Others
Laudexium is a neuromuscular blocking drug or skeletal muscle relaxant in the category of non-depolarizing neuromuscular-blocking drugs. It is used adjunctively in surgical anesthesia to facilitate endotracheal intubation and to provide skeletal muscle re
T21427 Mexiletine

Mexitil,Mexiletene,KO-1173,KO1173,KO 1173

Others Others
Mexiletine is a non-selective voltage-gated sodium channel blocker. It is a medicine in the class of IB anti-arrhythmic. Mexiletine may also be used in patients experiencing refractory pain and is effective to treat muscle stiffness resulting from myotonic dystrophy or non-dystrophic myotonias.
T68645 Hexamethonium monotartrate

Others Others
Hexamethonium monotartrate is a non-depolarizing NMJ blocker and nAChR antagonist. It has previously been used to treat hypertension. It inhibits sympathetic nervous system activity and acts as a skeletal muscle relaxant.
T69161 Hexamethonium bromide dihydrate

Others Others
Hexamethonium bromide dihydrate is a non-depolarizing NMJ blocker and nAChR antagonist. It has previously been used to treat hypertension. It inhibits sympathetic nervous system activity and acts as a skeletal muscle relaxant.
T70269 Hexamethonium chloride dihydrate

Others Others
Hexamethonium chloride dihydrate is a non-depolarizing NMJ blocker and nAChR antagonist. It has previously been used to treat hypertension. It inhibits sympathetic nervous system activity and acts as a skeletal muscle relaxant.
T33638 Neostigmine Iodide

SB 24,SB24,TL1321,TL 1321,TL-1321,SB-24

Others Others
Neostigmine Iodide is a parasympathic compound used as a reversible acetylcholinesterase inhibitor to improve muscle tone in patients with myasthenia gravis and in routine anesthesia to reverse the effects of non-depolarizing muscle relaxants such as rocu
T21449 GYKI-52466

GYKI 52,466,GYKI-5,2466,GYKI52,466

Others Others
GYKI-52466 is a selective non-competitive AMPA receptor antagonist (IC50 values are 10-20, ~ 450 and >50 μM for AMPA-, kainate- and NMDA-induced responses, respectively) used as a Skeletal muscle relaxant, orally active anticonvulsant, neuroprotective and
T40431 Anabaseine

Others Others
Anabaseine is a non-selective nicotinic agonist that stimulates all alpha-7 subtypes of AChRs, with a preference for skeletal muscle and brain. Additionally, it acts as a weak partial agonist at alpha-4 beta-2 nAChRs.
T11522 GYKI 52466 dihydrochloride

Others Others
GYKI 52466 dihydrochloride is orally active and non-competitive kainate- and AMPA-activated currents antagonist (IC50s: 7.5 μM and 11 μM). It is inactive against NMDA or γ-aminobutyric acid responses. It is a muscle relaxant and anticonvulsant agent and h
T36335 (S)-nitro-Blebbistatin

Others Others
(S)-nitro-Blebbistatin is a more stable form of (-)-blebbistatin , which is a selective cell-permeable inhibitor of non-muscle myosin II ATPases. (-)-Blebbistatin rapidly and reversibly inhibits Mg-ATPase activity and in vitro motility of non-muscle myosin IIA and IIB for several species (IC50s = 0.5-5 μM), while poorly inhibiting smooth muscle myosin (IC50 = 80 μM). Through these effects, it blocks apoptosis-related bleb formation, directed cell migration, and cytokinesis in vertebrate cells. H...
T85155 (S)-3'-hydroxy Blebbistatin

(−)-3'-hydroxy Blebbistatin​,meta-hydroxy-Blebbistatin,m-hydroxy-Blebbistatin

Others Others
(S)-3'-hydroxy-Blebbistatin is a more stable and less phototoxic derivative of (–)-blebbistatin, retaining the latter's properties as a selective, cell-permeable inhibitor of non-muscle myosin II ATPases. Unlike its predecessor, (S)-3'-hydroxy-Blebbistatin exhibits reduced fluorescence, improving its utility in live cell imaging applications by diminishing degradation into cytotoxic intermediates under blue light exposure (450-490 nm). It effectively inhibits the Mg-ATPase activity and in vitro ...
T31845 Forasartan

SC52458,SC 52458,SC-52458

Others Others
Forasartan is a non - peptide angiotensin II receptor antagonist with antihypertensive activity. Forasartan and angiotensin II compete to bind AT1 receptor subtypes in vascular smooth muscle, thereby blocking angiotensin II-mediated vasoconstriction, lead
T85257 (S)-3'-amino Blebbistatin

meta-amino Blebbistatin,(−)-3'-amino Blebbistatin,m-amino Blebbistatin

Others Others
"(S)-3'-amino Blebbistatin, retaining the active stereochemistry of the less stable and more phototoxic (–)-blebbistatin, serves as a refined selective cell-permeable inhibitor of non-muscle myosin II ATPases. This compound efficaciously inhibits the Mg-ATPase activity and in vitro motility of non-muscle myosin IIA and IIB across several species with IC50s ranging from 0.5-5 µM, and exhibits minimal inhibition against smooth muscle myosin (IC50= 80 µM). Its primary functions include obstructing ...
T37702 Pancuronium (bromide hydrate)

Others Others
Pancuronium is an aminosteroid antagonist of muscle-type nicotinic acetylcholine receptors (nAChRs) with an IC50value of 14.8 nM using patch clamp electrophysiology in BOSC23 cells expressing mouse nAChRs.1It acts as a non-depolarizing neuromuscular blocking agent.2Pancuronium enhances anesthesia induced by isoflurane , reducing immobilization with an ED50value of 1.62 μg/kg.3 1.Liu, M., and Dilger, J.P.Site selectivity of competitive antagonists for the mouse adult muscle nicotinic acetylcholin...
TP2086 AdTx1

Selective, high affinity, non-competitive α1A adrenoceptor antagonist (Ki = 0.35 nM). Exhibits no significant activity against a range of other GPCRs, including α2A, β1 and β2 adrenoceptors. Antagonizes effects of phenylephrine on isolated rabbit prostate
T71207 (R)-(+)-Blebbistatin O-Benzoate

Others Others
(R)-(+)-Blebbistatin O-Benzoate is a derivative of Blebbistatin. (R)-(+)-Blebbistatin is a 1-phenyl-2-pyrrolidinone derivative and a selective inhibitor of non-muscle myosin II. It blocks cell blebbing rapidly and reversibly and also disrupts directed cell migration and cytokinesis in vertebrate cell. (R)-(+)-Blebbistatin can also inhibit contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly. (R)-(+)-Blebbistatin is suitable as a negative control for (S)-(-)-...
T36554 TMB 8 (hydrochloride)

Others Others
TMB 8 is a non-competitive antagonist of nicotinic acetylcholine receptors (nAChRs) with IC50 values of 390 and 350 nM, respectively, for human muscle-type and α3β4 subunit-containing ganglionic nAChRs expressed in TE671/RD or SH-SY5Y cells. It inhibits nicotine-induced dopamine release from rat brain synaptosomes (IC50 = 480 nM). TMB 8 also reduces calcium availability in smooth and skeletal muscle, blocking the contractile response in isolated rabbit aortic strip when used at a concentration o...
T36400 para-amino-Blebbistatin

Others Others
para-amino-Blebbistatin is a more water-soluble form of (S)-4'-nitro-blebbistatin , which is a more stable and less phototoxic form of (-)-blebbistatin .1,2,3 (-)-Blebbistatin is a selective cell-permeable inhibitor of non-muscle myosin II ATPases that rapidly and reversibly inhibits Mg-ATPase activity and in vitro motility of non-muscle myosin IIA and IIB for several species (IC50s = 0.5-5 μM), while poorly inhibiting smooth muscle myosin (IC50 = 80 μM).2,3,4 Through these effects, it blocks ap...
T12342 P053

Others Others
P053 是一种有效的,非竞争性和选择性的神经酰胺合酶1 (CerS1) 抑制剂(IC50= 0.5 μM)。P053 作为肌肉线粒体脂肪酸氧化的内源性抑制剂和全身肥胖调节剂。
T37733 AMP-PNP tetralithium

Others Others
Non-hydrolyzable AMP analog. Kir6 (KATP) channel blocker. Inhibits fast axonal transport and stabilizes the interaction of membranous organelles with microtubules. Brady (1985) A novel brain ATPase with properties expected for the fast axonal transport motor. Nature 317 73 PMID:2412134 |Yount et al (1971) Adenylyl imidodiphosphate, an adenosine triphosphate analog containing a P-N-P linkage. Biochemistry 10 2484 PMID:4326768 |Hehl and Neumcke (1994) KATP channels of mouse skeletal muscle: mechan...
T76305 [Ala2] Endothelin-3, human

[Ala2] Endothelin-3, human 为ET-3的线性类似物,其结构中的Cys残基被Ala所替代。ET-3是由人体横纹肌肉瘤细胞系产生,且仅在此细胞系中表达的一种具有血管活性的肽。在非肌肉来源的肉瘤细胞系中不表达。该肽能够作为旁分泌因子,促进内皮细胞迁移。
T36186 Globotriaosylceramides (porcine)

Others Others
Globotriaosycleramides are glycosphingolipids found in mammalian cell membranes that are synthesized from lactosylceramides . They act as receptors for Shiga and Shiga-like toxins in vitro and in vivo. Globotriaosylceramides accumulate in endothelial cells, pericytes, vascular smooth muscle cells, renal epithelial cells, dorsal ganglia neuronal cells, and myocardial cells in patients with Fabry disease, a lysosomal storage disorder characterized by a deficiency in the enzyme α-galactosidase A. G...
T76565 PDC31

PDC31 (THG113.31; ILGHXDYK) 是FPProstaglandin Receptor 的变构和非竞争性抑制剂。PDC31是基于D-氨基酸的寡肽,用作平滑肌收缩剂。PDC31 在体内降低子宫收缩的强度和持续时间,可用于早产和原发性痛经 (PD) 的研究。PDC31 还增强人子宫肌层细胞中 Ca2+依赖性大电导 K+通道。
T1203 Nadolol

Anabet,Corgard,Solgol,苯甲丁氮酮,纳多洛尔,SQ11725

Adrenergic Receptor GPCR/G Protein; Neuroscience
Nadolol 是一种有机阴离子转运多肽 1A2 (OATP1A2) 的底物,是一种非选择性的、具有口服活性的 β-肾上腺素受体 (β-adrenergic receptors) 阻滞剂,可用于高血压,心绞痛和血管性头痛的研究。
T35604 Osteocalcin (1-49) (human) (trifluoroacetate salt)

Osteocalcin (1-49) is a non-collagenous peptide that is secreted by osteoblasts and odontoblasts and comprises 1-2% of the total protein in bone. Secretion of osteocalcin (1-49) is stimulated by 1,25-dihydroxy vitamin D and plasma levels increase in diseases that induce dysregulated bone turnover such as osteoporosis, Paget's disease, and primary hyperparathyroidism. Osteocalcin (1-49) is positively correlated with insulin sensitivity and negatively correlated with high blood glucose levels in w...

化合物

Mivacurium dichloride
Cat.No: T22371
Synonym: 米库氯铵,Mivacurium chloride,二氯美维库铵
Target: AChR
Blebbistatin
Cat.No: T21550
Synonym: (±)-Blebbistatin
Target: ATPase, Myosin
(-)-Blebbistatin
Cat.No: T6038
Synonym: (S)-(-)-Blebbistatin
Target: ATPase, Myosin
Rocuronium bromide
Cat.No: T0156
Synonym: ORG 9426,罗库溴铵,ORG 9426 (Bromide)
Target: AChR
Tuna AI acetate
Cat.No: T24906L
Synonym:
Target: Angiotensin-converting Enzyme (ACE)
Pipecuronium bromide
Cat.No: T12481
Synonym: RGH-1106
Target: AChR
Chlormezanone
Cat.No: T0715
Synonym: Trancopal,氯美扎酮,芬那露
Target: Others, GABA Receptor
Vecuronium bromide
Cat.No: T1594
Synonym: ORG NC 45,维库溴铵
Target: AChR
Ro 46-2005
Cat.No: T3194
Synonym:
Target: Endothelin Receptor
Felbinac
Cat.No: T0888
Synonym: Dapson,4-联苯乙酸,4-Biphenylacetic acid
Target: COX
Phenytoin
Cat.No: T0939
Synonym: 苯妥英,Diphenylhydantoin,5,5-Diphenylhydantoin
Target: Virus Protease, Sodium Channel
Lanperisone HCl
Cat.No: T71356
Synonym: NK 433
Target: Apoptosis
Ostarine
Cat.No: T2408
Synonym: MK-2866,GTX-024,Enobosarm
Target: Androgen Receptor
Phenoxybenzamine hydrochloride
Cat.No: T1158
Synonym: 苯氧苯札明,NCI-c01661,NSC 37448,盐酸酚苄明,Phenoxybenzamine HCl
Target: CaMK, Adrenergic Receptor
L-Asparaginase
Cat.No: TP1115
Synonym: L-​ASNase
Target: Others
NS-2028
Cat.No: T16344
Synonym:
Target: Others, Guanylate cyclase
Alcuronium free base
Cat.No: T29846
Synonym: Alcuronium,Alcuronum,Diallylnortoxiferine,Alcuronium kation,Alloferine
Target: Others
Laudexium
Cat.No: T25636
Synonym: Laudexium ion,Laudexium cation
Target: Others
Mexiletine
Cat.No: T21427
Synonym: Mexitil,Mexiletene,KO-1173,KO1173,KO 1173
Target: Others
Hexamethonium monotartrate
Cat.No: T68645
Synonym:
Target: Others
Hexamethonium bromide dihydrate
Cat.No: T69161
Synonym:
Target: Others
Hexamethonium chloride dihydrate
Cat.No: T70269
Synonym:
Target: Others
Neostigmine Iodide
Cat.No: T33638
Synonym: SB 24,SB24,TL1321,TL 1321,TL-1321,SB-24
Target: Others
GYKI-52466
Cat.No: T21449
Synonym: GYKI 52,466,GYKI-5,2466,GYKI52,466
Target: Others
Anabaseine
Cat.No: T40431
Synonym:
Target: Others
GYKI 52466 dihydrochloride
Cat.No: T11522
Synonym:
Target: Others
(S)-nitro-Blebbistatin
Cat.No: T36335
Synonym:
Target: Others
(S)-3'-hydroxy Blebbistatin
Cat.No: T85155
Synonym: (−)-3'-hydroxy Blebbistatin​,meta-hydroxy-Blebbistatin,m-hydroxy-Blebbistatin
Target: Others
Forasartan
Cat.No: T31845
Synonym: SC52458,SC 52458,SC-52458
Target: Others
(S)-3'-amino Blebbistatin
Cat.No: T85257
Synonym: meta-amino Blebbistatin,(−)-3'-amino Blebbistatin,m-amino Blebbistatin
Target: Others
Pancuronium (bromide hydrate)
Cat.No: T37702
Synonym:
Target: Others
AdTx1
Cat.No: TP2086
Synonym:
Target:
(R)-(+)-Blebbistatin O-Benzoate
Cat.No: T71207
Synonym:
Target: Others
TMB 8 (hydrochloride)
Cat.No: T36554
Synonym:
Target: Others
para-amino-Blebbistatin
Cat.No: T36400
Synonym:
Target: Others
P053
Cat.No: T12342
Synonym:
Target: Others
AMP-PNP tetralithium
Cat.No: T37733
Synonym:
Target: Others
[Ala2] Endothelin-3, human
Cat.No: T76305
Synonym:
Target:
Globotriaosylceramides (porcine)
Cat.No: T36186
Synonym:
Target: Others
PDC31
Cat.No: T76565
Synonym:
Target:
Nadolol
Cat.No: T1203
Synonym: Anabet,Corgard,Solgol,苯甲丁氮酮,纳多洛尔,SQ11725
Target: Adrenergic Receptor
Osteocalcin (1-49) (human) (trifluoroacetate salt)
Cat.No: T35604
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T4934 1-Methyl-L-histidine

1-甲基-L-组氨酸,3-(1-Methylimidazol-4-yl)-L-alanine,Nτ-Methyl-L-histidine

Endogenous Metabolite Metabolism
1-Methyl-L-histidine (3-(1-Methylimidazol-4-yl)-L-alanine),一种人内源性代谢物,是肉类和外源性 3-methylhistidine 摄入的客观生物标记。
T2520 Desloratadine

Sch34117,地氯雷他定,NSC 675447

Endogenous Metabolite; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience
Desloratadine (Sch34117) 是非镇静H1抗组胺药 Loratadine 的主要口服代谢物,可减少对支气管平滑肌、毛细血管和胃肠道平滑肌中 H1 受体的典型组胺能作用,包括血管舒张、支气管收缩、血管通透性增加、疼痛、瘙痒和胃肠道平滑肌的痉挛性收缩。它是一种选择性H1受体拮抗剂,具有抗过敏和抗炎活性。
T0962 L-Hyoscyamine

Daturine,Hyoscyamine,L-莨菪碱,L-天仙子胺

AChR Neuroscience
L-Hyoscyamine (Daturine) 是从山莨菪中提取的一种托烷生物碱,是竞争性的毒蕈碱受体拮抗剂。它是 Atropine 的左旋异构体。
T4S1619 L-Hyoscyamine sulfate

Hyoscyamine sulfate hydrate,Levsin Sulfate,Hyoscyamine Sulphate,硫酸天仙子胺水合物,L-莨菪碱硫酸盐

AChR Neuroscience
L-Hyoscyamine sulfate (Levsin Sulfate) 是来自山莨菪的一种托烷生物碱,是竞争性的毒蕈碱受体拮抗剂。它是 Atropine 的左旋异构体。
T3S0737 Flavokawain A

2'-羟基-4,4',6'-三甲氧基查耳酮,Flavokavain A

Apoptosis; p38 MAPK Apoptosis; MAPK
Flavokawain A (Flavokavain A) 是 kava 提取物中的查耳酮,是一种抗癌试剂,具有抗肿瘤活性。它通过 Bax 蛋白依赖和线粒体依赖的凋亡途径诱导细胞凋亡,有潜力用于膀胱癌的相关研究。
T4776 Glycerol

Glycerin,甘油

Endogenous Metabolite Metabolism
Glycerol 是甘油三酯(即脂肪和油)和磷脂的重要成分。它在食品工业中被广泛用作甜味剂和保湿剂以及药物制剂。
T41276 Peimisine hydrochloride

Peimisine hydrochloride 非竞争性拮抗气管平滑肌 M 受体,抑制 Ach 引起的平滑肌收缩。它兴奋 β 受体和拮抗内钙释放,促进一氧化氮释放,可舒张气管平滑肌,有平喘作用。

天然产物

1-Methyl-L-histidine
Cat.No: T4934
Synonym: 1-甲基-L-组氨酸,3-(1-Methylimidazol-4-yl)-L-alanine,Nτ-Methyl-L-histidine
Target: Endogenous Metabolite
Desloratadine
Cat.No: T2520
Synonym: Sch34117,地氯雷他定,NSC 675447
Target: Endogenous Metabolite, Histamine Receptor
L-Hyoscyamine
Cat.No: T0962
Synonym: Daturine,Hyoscyamine,L-莨菪碱,L-天仙子胺
Target: AChR
L-Hyoscyamine sulfate
Cat.No: T4S1619
Synonym: Hyoscyamine sulfate hydrate,Levsin Sulfate,Hyoscyamine Sulphate,硫酸天仙子胺水合物,L-莨菪碱硫酸盐
Target: AChR
Flavokawain A
Cat.No: T3S0737
Synonym: 2'-羟基-4,4',6'-三甲氧基查耳酮,Flavokavain A
Target: Apoptosis, p38 MAPK
Glycerol
Cat.No: T4776
Synonym: Glycerin,甘油
Target: Endogenous Metabolite
Peimisine hydrochloride
Cat.No: T41276
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPY-03607 Cofilin Protein, Human, Recombinant (His)

CFL,HEL-S-15,cofilin 1 (non-muscle)

Human E. coli
CFL1, also known as n-cofilin, is a member of the ADF/Cofilin family. This family comprises three genes: CFL1, CFL2 and DSTN (destrin). ADF/Cofilin family members bind G-actin monomers and depolymerize actin filaments through two mechanisms: severing and increasing the off-rate for actin monomers from the pointed end. Cofilin also binds with other proteins such as myosin, tropomyosin, α-actinin, gelsolin and scruin. These proteins compete with cofilin for actin binding. Сofilin also plays a...
TMPH-01729 Myosin-9/MYH9 Protein, Human, Recombinant (GST)

Myosin-9,MYH9,Myosin heavy chain 9,Myosin heavy chain, n...

Human E. coli
Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Required for cortical actin clearance prior to oocyte exocytosis. Promotes cell motility in conjunction with S100A4. During cell spreading, plays an important role in cytoskeleton reorganization, focal contact formation (in the margins but not the central part of spreading cells), and lamellipodial retraction; this function is mechanically antagonized by MYH10. Myosin-...
TMPH-01342 Filamin-A Protein, Human, Recombinant (His & Myc)

FLNA,Filamin-1,Actin-binding protein 280,Alpha-filamin,Endot...

Human E. coli
Filamin-A Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 38.0 kDa and the accession number is P21333.
TMPY-05030 PCDH7 Protein, Human, Recombinant (His)

BHPCDH

Human Baculovirus Insect Cells
PCDH7, a member of protocadherins family, functions as tumor suppressor in several human cancers. The human PCDH7 gene is localized in chromosome 4p15, which is often inactivated in human cancers, including bladder cancer. The low PCDH7 expression is a potential prognostic biomarker for primary non-muscle invasive bladder cancer (NMIBC). PCDH7 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 94 kDa and the accession number...
TMPJ-00071 EPO/Erythropoietin Protein, Human, Recombinant (His)

Erythropoietin,EPO,红细胞生长素,Epoetin

Human HEK293 Cells
Erythropoietin (EPO) is a glycoprotein hormone that is principally known for its role in erythropoiesis, where it is responsible for stimulating proliferation and differentiation of erythroid progenitor cells. Erythropoietin is a member of the EPO/TPO family. It is a secreted, glycosylated cytokine composed of four alpha helical bundles. The differentiation of CFU-E (Colony Forming Unit-Erythroid) cells into erythrocytes can only be accomplished in the presence of EPO. Physiological levels of EP...
TMPH-02253 TPM2 Protein, Human, Recombinant (His)

TPM2,Tropomyosin-2,Tropomyosin beta chain,Beta-tropomyosin

Human E. coli
Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. The non-muscle isoform may have a role in agonist-mediated receptor internalization.
TMPH-02252 TPM3 Protein, Human, Recombinant (GST)

Gamma-tropomyosin,Tropomyosin alpha-3 chain,Tropomyosin-3,TP...

Human E. coli
Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.
TMPH-03212 TPM1 Protein, Rabbit, Recombinant (His & Myc)

TPM1,Alpha-tropomyosin,Tropomyosin alpha-1 chain,Tropomyosin...

Rabbit Baculovirus Insect Cells
Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. TPM1 Protein, Rabbit, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 3...
TMPY-03984 TPM1 Protein, Human, Recombinant (His)

TMSA,tropomyosin 1 (alpha),LVNC9,CMH3,HTM-alpha,CMD1Y,C15orf...

Human E. coli
TPM1, also known as tropomyosin-1, is a member of the tropomyosin family. Members of this family are highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. TPM1 is one type of alpha-helical chain that forms the predomin...
TMPH-03213 TPM1 Protein, Rabbit, Recombinant (E. coli, His & Myc)

Tropomyosin alpha-1 chain,TPM1,Alpha-tropomyosin,Tropomyosin...

Rabbit E. coli
Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. TPM1 Protein, Rabbit, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular w...
TMPY-03600 TPM4 Protein, Human, Recombinant (His)

tropomyosin 4,HEL-S-108,TPM4

Human HEK293 Cells
TPM4, also known as tropomyosin 4, is a member of the tropomyosin family. Members of this family are actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. TPM4 is expressed in cardiac tissue and platelets. It is highly expressed in the platelets of hypertensive patients. TPM4 plays a central role, in association with the troponin complex, in the calcium-dependent regulation of vertebrate striated muscle contraction. Smo...
TMPH-02205 Titin Protein, Human, Recombinant (His)

Connectin,TTN,Rhabdomyosarcoma antigen MU-RMS-40.14,Titin

Human E. coli
Key component in the assembly and functioning of vertebrate striated muscles. By providing connections at the level of individual microfilaments, it contributes to the fine balance of forces between the two halves of the sarcomere. The size and extensibility of the cross-links are the main determinants of sarcomere extensibility properties of muscle. In non-muscle cells, seems to play a role in chromosome condensation and chromosome segregation during mitosis. Might link the lamina network to ch...
TMPY-06762 PCDH7 Protein, Human, Recombinant (His & Avi), Biotinylated

BHPCDH

Human Baculovirus Insect Cells
PCDH7, a member of protocadherins family, functions as tumor suppressor in several human cancers. The human PCDH7 gene is localized in chromosome 4p15, which is often inactivated in human cancers, including bladder cancer. The low PCDH7 expression is a potential prognostic biomarker for primary non-muscle invasive bladder cancer (NMIBC). PCDH7 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in Baculovirus insect cells with His and Avi tag. The predicted molecular weight is 95....
TMPY-04471 APEG1 Protein, Human, Recombinant (His)

SPEG complex locus,BPEG,SPEGalpha,SPEGβ,APEG-1,SPEGbeta,APEG...

Human E. coli
Striated muscle preferentially expressed protein kinase, also known as aortic preferentially expressed protein 1, APEG-1, SPEG and KIAA1297, is a protein that belongs to the protein kinase superfamily and CAMK Ser/Thr protein kinase family. SPEG / APEG-1 contains two fibronectin type-III domains, nine Ig-like (immunoglobulin-like) domains, two protein kinase domains. Isoform 1 of SPEG is preferentially expressed in striated muscle. Non-kinase form such as isoform 3 of SPEG is predominantly expre...
TMPY-03863 CAPG Protein, Human, Recombinant

capping protein (actin filament), gelsolin-like,HEL-S-66,MCP...

Human E. coli
CAPG, also known as actin Regulatory Protein CAPG, is a a member of the gelsolin/villin family. Members of this family are actin-regulatory proteins. CAPG reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. By capping the barbed ends of actin filaments, CAPG contributes to the control of actin-based motility in non-muscle cells. CAPG may also play an important role in macrophage function.
TMPJ-01362 UBAP1 Protein, Human, Recombinant (His)

Nasopharyngeal Carcinoma-Associated Gene 20 Protein,UBAP1,Ub...

Human E. coli
Ubiquitin-Associated Protein 1 (UBAP1) belongs to the UBA domain family. Members of this family are related to ubiquitin and the ubiquitination pathway. Because of their cytogenetic location, this UBA domain family member is being studied as a putative target for mutation in nasopharyngeal carcinomas. UBAP1 is highly expressed in the heart, brain, placenta, lung, skeletal muscle, liver, and pancreas. UBAP1 consists of two UBA domains and one UMA domain. The ubiquitin associated domain is through...
TMPY-03125 SHP-2 Protein, Mouse, Recombinant (His)

SAP-2,Syp,PTP1D,SH-PTP2,SH-PTP3,SHP-2,PTP2C,2700084A17Rik,AW...

Mouse HEK293 Cells
SHP2, also known as PTPN11, belongs to the protein-tyrosine phosphatase(PTP) family, non-receptor class 2 subfamily. PTPs catalyze the removal of phosphate groups from tyrosine residues by the hydrolysis of phosphoric acid monoesters. They dephosphorylate EGFR, JAK2 and TYK2 kinases, promoting oncogenic transformation. SHP2 is widely expressed, with highest levels in heart, brain, and skeletal muscle. SHP2 acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participat...
TMPH-01258 DAG1 Protein, Human, Recombinant (His & Myc)

Dystrophin-associated glycoprotein 1,Dystroglycan,Dystroglyc...

Human Baculovirus Insect Cells
The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization.; Extracellular peripheral glycoprotein that acts as a receptor for extracellular matrix proteins containing laminin-G domains. Receptor for laminin-2 (LAMA2) and agrin in peripheral nerve Schwann cells. Also acts as a receptor for laminin LAMA5.; Transmembra...
TMPJ-00158 Apolipoprotein A-I/APOA1 Protein, Human, Recombinant

Apolipoprotein A-I,APOA1,Apo-AI,ApoA-I

Human E. coli
Apolipoprotein A1 (APOA1) is a secreted protein which belongs to the Apolipoprotein A1/A4/E family. APOA1 is the major protein component of high density lipoprotein (HDL) in plasma. APOA1 plays a critical role in various biological processes, such as Cholesterol metabolism, Lipid metabolism and transport, Steroid metabolism. APOA1 promotes cholesterol efflux from tissues to the liver and thus helps to clear cholesterol from arteries. Defects in this gene resulted in HDL deficiencies, including T...
TMPJ-01386 STUB1 Protein, Human, Recombinant

Carboxy Terminus of Hsp70-Interacting Protein,STIP1 Homology...

Human E. coli
E3 Ubiquitin-Protein Ligase CHIP is a cytoplasmic protein. CHIP is highly expressed in skeletal muscle, heart, pancreas, brain and placenta. CHIP interacts with the molecular chaperones Hsc70-Hsp70 and Hsp90 through its TPR domain; lead to in client substrate ubiquitylation and degradation by the proteasome. CHIP targets misfolded chaperone substrates towards proteasomal degradation. CHIP mediates transfer of non-canonical short ubiquitin chains to HSPA8 that have no effect on HSPA8 degradation....
TMPY-01204 SMYD2 Protein, Human, Recombinant (His)

ZMYND14,SET and MYND domain containing 2,HSKM-B,KMT3C

Human Baculovirus Insect Cells
SET and MYND domain-containing protein 2, also known as HSKM-B, SMYD2, and KMT3C, is a member of the SMYD protein family. It contains one MYND-type zinc finger and one SET domain. Not much is known about SMYD2. However, the interest in better understanding the roles of SMYD2 has grown because of reports indicating that SMYD2 methylates p53 and histone H3. In Xenopus, SMYD1 and SMYD2 were expressed in various muscle tissues and related to muscle cell differentiation. SMYD2 mRNA is most highly exp...
TMPY-02945 Prokineticin 1/EG-VEGF Protein, Human, Recombinant (His)

PK1,EGVEGF,PRK1,prokineticin 1

Human Baculovirus Insect Cells
EG-VEGF, also known as prokineticin-1, is a member of the AVIT (prokineticin) family. Prokineticins are secreted proteins that can promote angiogenesis and induce strong gastrointestinal smooth muscle contraction. EG-VEGF can be detected in the steroidogenic glands, ovary, testis, adrenal and placenta. EG-VEGF has little or no effect on a variety of other endothelial and non-endothelial cell types. It induces proliferation, migration and fenestration (the formation of membrane discontinuities) i...
TMPY-05353 CCL26 Protein, Human, Recombinant

MIP-4alpha,SCYA26,MIP-4a,chemokine (C-C motif) ligand 26,IMA...

Human Baculovirus Insect Cells
The eotaxin subfamily of CC chemokines consists of eotaxin-1/CCL11, eotaxin-2/CCL24 and eotaxin-3/CCL26. All eotaxins induce the trafficking of eosinophils to the sites of inflammation via CC chemokine receptor 3 (CCR3), which is also expressed by several different cell types, including basophils, dendritic cells, smooth muscle cells, epithelial cells and fibroblasts. The sequence similarity between the three eotaxins is limited (<4%), but their functional properties are very similar. Eotaxin-1 ...
TMPY-02193 GOLPH2/GOLM1 Protein, Human, Recombinant (His)

HEL46,PSEC0257,GOLPH2,bA379P1.3,C9orf155,GP73,golgi membrane...

Human HEK293 Cells
Golgi membrane protein 1, also known as Golgi membrane protein GP73, Golgi phosphoprotein 2, and GOLM1, is a protein that belongs to the GOLM1 / CASC4 family. GOLM1 is widely expressed. It is highly expressed in the colon, prostate, trachea, and stomach. It is expressed at a lower level in testis, muscle, lymphoid tissues, white blood cells, and spleen. It is predominantly expressed by cells of the epithelial lineage. GOLM1 is expressed at a low level in the normal liver. Expression significantl...
TMPJ-00948 Endostatin Protein, Mouse, Recombinant (His)

antiangiogenic agent,type XVIII,collagen α-1(XVIII)chain,col...

Mouse HEK293 Cells
Endostatin, an endogenous non‑glycosylated inhibitor of endothelial cell proliferation and angiogenesis. It is produced and/or trimmed by metalloproteinases such as MMP‑2 and MMP‑9, and cathepsins S, B and L. The N‑terminal ~27 aa of Endostatin appear to contain the majority of its activity. This region contains zinc binding sites that are thought to be critical for its anti‑endothelial and anti‑tumor effects, as well as multiple cleavage sites that, when used, can modify its activity. Mouse End...
TMPY-03504 CBFB Protein, Human, Recombinant (His)

core-binding factor, β subunit,core-binding factor, beta sub...

Human E. coli
CBFB is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and osteogenesis (e.g., RUNX2). CBFB is a non-DNA binding regulatory subunit; it allosterically enhances DNA binding by alpha subunit as the complex binds to the core site of various enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enh...
TMPY-04461 TRIB3 Protein, Human, Recombinant (GST)

SKIP3,C20orf97,tribbles pseudokinase 3,TRB3,SINK,NIPK

Human Baculovirus Insect Cells
Tribbles homolog 3, also known as Neuronal cell death-inducible putative kinase, p65-interacting inhibitor of NF-kappa-B, SINK and TRIB3, is a Nucleus protein that belongs to the protein kinase superfamily and CAMK Ser/Thr protein kinase family and Tribbles subfamily. Highest expression Of TRIB3 is in liver, pancreas, peripheral blood leukocytes and bone marrow. It is also highly expressed in a number of primary lung, colon and breast tumors. TRIB3 is expressed in spleen, thymus, and prostate an...
TMPY-02242 Serpin B6 Protein, Human, Recombinant (His)

DKFZp686I04222,PTI,SPI3,PI-6,RP1-90J20.6,serpin peptidase in...

Human Baculovirus Insect Cells
SerpinB6, also known as Cytoplasmic antiproteinase, Peptidase inhibitor 6, Placental thrombin inhibitor, SERPINB6 and PI-6, is a cytoplasm protein that belongs to the serpin family and Ov-serpin subfamily. SerpinB6 / PI-6 is an inhibitor of cathepsin G, kallikrein-8 and thrombin. It may play an important role in the inner ear in the protection against leakage of lysosomal content during stress and loss of this protection results in cell death and sensorineural hearing loss. SerpinB6 / PI-6 is ex...
TMPH-03753 MYLK Protein, Human, Recombinant (His)

MYLK,Myosin light chain kinase, smooth muscle,Telok...

Human E. coli
Calcium/calmodulin-dependent myosin light chain kinase implicated in smooth muscle contraction via phosphorylation of myosin light chains (MLC). Also regulates actin-myosin interaction through a non-kinase activity. Phosphorylates PTK2B/PYK2 and myosin light-chains. Involved in the inflammatory response (e.g. apoptosis, vascular permeability, leukocyte diapedesis), cell motility and morphology, airway hyperreactivity and other activities relevant to asthma. Required for tonic airway smooth muscl...

重组蛋白

Cofilin Protein, Human, Recombinant (His)
Cat.No: TMPY-03607
Species: Human
Expression System: E. coli
Myosin-9/MYH9 Protein, Human, Recombinant (GST)
Cat.No: TMPH-01729
Species: Human
Expression System: E. coli
Filamin-A Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-01342
Species: Human
Expression System: E. coli
PCDH7 Protein, Human, Recombinant (His)
Cat.No: TMPY-05030
Species: Human
Expression System: Baculovirus Insect Cells
EPO/Erythropoietin Protein, Human, Recombinant (His)
Cat.No: TMPJ-00071
Species: Human
Expression System: HEK293 Cells
TPM2 Protein, Human, Recombinant (His)
Cat.No: TMPH-02253
Species: Human
Expression System: E. coli
TPM3 Protein, Human, Recombinant (GST)
Cat.No: TMPH-02252
Species: Human
Expression System: E. coli
TPM1 Protein, Rabbit, Recombinant (His & Myc)
Cat.No: TMPH-03212
Species: Rabbit
Expression System: Baculovirus Insect Cells
TPM1 Protein, Human, Recombinant (His)
Cat.No: TMPY-03984
Species: Human
Expression System: E. coli
TPM1 Protein, Rabbit, Recombinant (E. coli, His & Myc)
Cat.No: TMPH-03213
Species: Rabbit
Expression System: E. coli
TPM4 Protein, Human, Recombinant (His)
Cat.No: TMPY-03600
Species: Human
Expression System: HEK293 Cells
Titin Protein, Human, Recombinant (His)
Cat.No: TMPH-02205
Species: Human
Expression System: E. coli
PCDH7 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06762
Species: Human
Expression System: Baculovirus Insect Cells
APEG1 Protein, Human, Recombinant (His)
Cat.No: TMPY-04471
Species: Human
Expression System: E. coli
CAPG Protein, Human, Recombinant
Cat.No: TMPY-03863
Species: Human
Expression System: E. coli
UBAP1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01362
Species: Human
Expression System: E. coli
SHP-2 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-03125
Species: Mouse
Expression System: HEK293 Cells
DAG1 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-01258
Species: Human
Expression System: Baculovirus Insect Cells
Apolipoprotein A-I/APOA1 Protein, Human, Recombinant
Cat.No: TMPJ-00158
Species: Human
Expression System: E. coli
STUB1 Protein, Human, Recombinant
Cat.No: TMPJ-01386
Species: Human
Expression System: E. coli
SMYD2 Protein, Human, Recombinant (His)
Cat.No: TMPY-01204
Species: Human
Expression System: Baculovirus Insect Cells
Prokineticin 1/EG-VEGF Protein, Human, Recombinant (His)
Cat.No: TMPY-02945
Species: Human
Expression System: Baculovirus Insect Cells
CCL26 Protein, Human, Recombinant
Cat.No: TMPY-05353
Species: Human
Expression System: Baculovirus Insect Cells
GOLPH2/GOLM1 Protein, Human, Recombinant (His)
Cat.No: TMPY-02193
Species: Human
Expression System: HEK293 Cells
Endostatin Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00948
Species: Mouse
Expression System: HEK293 Cells
CBFB Protein, Human, Recombinant (His)
Cat.No: TMPY-03504
Species: Human
Expression System: E. coli
TRIB3 Protein, Human, Recombinant (GST)
Cat.No: TMPY-04461
Species: Human
Expression System: Baculovirus Insect Cells
Serpin B6 Protein, Human, Recombinant (His)
Cat.No: TMPY-02242
Species: Human
Expression System: Baculovirus Insect Cells
MYLK Protein, Human, Recombinant (His)
Cat.No: TMPH-03753
Species: Human
Expression System: E. coli
Cat. No. Product Name Target Signaling Pathways
TMIJ-0202 Desloratadine-d5

Desloratadine-d5 是 Desloratadine 的氘代化合物。Desloratadine 的 CAS 号为 100643-71-8。Desloratadine 是非镇静H1抗组胺药 Loratadine 的主要口服代谢物,可减少对支气管平滑肌、毛细血管和胃肠道平滑肌中 H1 受体的典型组胺能作用,包括血管舒张、支气管收缩、血管通透性增加、疼痛、瘙痒和胃肠道平滑肌的痉挛性收缩。它是一种选择性H1受体拮抗剂,具有抗过敏和抗炎活性。
T36384 DL-Tyrosine-13C9,15N

L-Tyrosine-13C9,15N

L-Tyrosine-13C9,15N is intended for use as an internal standard for the quantification of L-tyrosine by GC- or LC-MS. L-Tyrosine is a non-essential amino acid.1It is produced by hydroxylation of phenylalanine by phenylalanine hydroxylase but can also be obtained from dietary sources or degradation of endogenous proteins, resulting in L-tyrosine release.1,2L-Tyrosine is a precursor in the biosynthesis of catecholamine neurotransmitters, melanins, and thyroid hormones.3Plasma, skeletal muscle, and...
TMID-0097 Ethyl-d5-malonic Acid

Ethyl-d5-malonic Acid 是 Ethyl-malonic Acid 的氘代化合物。Ethyl-malonic Acid 的 CAS 号为 601-75-2。Ethylmalonic acid 是潜在有毒物质,非致癌性,与神经性厌食和甲氧基脱羧酶缺乏症有关。
TMIJ-0317 Nadolol-d9 (Mixture of Diastereomers)

Nadolol-d9 (Mixture of Diastereomers) 是 Nadolol 的氘代化合物。Nadolol 的 CAS 号为 42200-33-9。Nadolol 是一种有机阴离子转运多肽 1A2 (OATP1A2) 的底物,是一种非选择性的、具有口服活性的 β-肾上腺素受体 (β-adrenergic receptors) 阻滞剂,可用于高血压,心绞痛和血管性头痛的研究。

同位素标记化合物

Desloratadine-d5
Cat.No: TMIJ-0202
Synonym:
Target:
DL-Tyrosine-13C9,15N
Cat.No: T36384
Synonym: L-Tyrosine-13C9,15N
Target:
Ethyl-d5-malonic Acid
Cat.No: TMID-0097
Synonym:
Target:
Nadolol-d9 (Mixture of Diastereomers)
Cat.No: TMIJ-0317
Synonym:
Target:
TargetMol Loading
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