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Search Results for " neurotrophic "

Targets Recommended: MAO Monoamine Oxidase

37

抑制剂 & 化合物

10

天然产物

1

化合物库

65

重组蛋白

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Cat. No.	Product Name
L6750	活血化瘀中药单体库		580 compounds
	580种来源于常见活血化瘀中药的单体化合物，是药物开发、药理研究等领域的有效工具。

化合物库

活血化瘀中药单体库

Cat.No: L6750

Compounds: 580

Cat. No.	Product Name	Target	Signaling Pathways
T0084	Moclobemide 吗氯贝胺,Ro111163	MAO; Monoamine Oxidase	Metabolism; Neuroscience
	Moclobemide (Ro111163) 是可逆的、可透过血脑屏障的单胺氧化酶 (MAO-A) 抑制剂，能够抑制 hMAO-A (IC50=6.061 μM)。它上调慢性应激小鼠海马祖细胞的增殖。
T34114	Posatirelin BRN 6006446,Posatirelinum,BRN-6006446,RGH-2202,BRN6006446	AChR	Neuroscience
	Posatirelin (BRN6006446) 是一种对单胺能和胆碱能系统具有调节活性和神经营养作用的合成肽，可用于研究血管性痴呆。
T7568	LM22A-4	Trk receptor	Tyrosine Kinase/Adaptors
	LM22A-4 是特异性的tyrosine kinase receptor B 激动剂，常用于研究神经系统疾病。
T4422	Edonerpic maleate T-817MA,T-817 maleate	Beta Amyloid	Neuroscience
	Edonerpic maleate (T-817 maleate) 是新神经营养剂，对淀粉样蛋白 β 肽具有抑制作用。
T21244	NSI-189 Phosphate NSI189 Phosphate,NSI 189 Phosphate,NSI-189磷酸盐	Others	Others
	NSI-189 Phosphate 是一种新型神经源性分子，具有多效性，包括临床前研究中证明的抗抑郁、促认知、突触和神经营养活性。其抗抑郁活性不依赖于单胺。
T13684	Equilin 7-Dehydroestrone	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Equilin (7-Dehydroestrone) 是神经营养性雌激素类固醇，具有血管扩张活性，通过 NF-κB 信号传导增加单核细胞-内皮粘附。Equilin 通过阻断Ca（2+）进入平滑肌来同样放松肠系膜动脉的阻力。
T10624	BT-13	c-RET	Apoptosis; Tyrosine Kinase/Adaptors
	BT-13 是一种胶质细胞源性神经营养因子 (GDNF) 受体 RET 的选择性激动剂，独立于 GDNF 配体发挥作用，能够促进体外感觉神经元神经突生长，减少大鼠神经病变的发生。
T77092	Nadecnemab REGN-5069	Others	Others
	Nadecnemab 是一种靶向胶质细胞源性神经营养因子家族受体 GFRA3 的 IgG4κ 抗体。Nadecnemab 可用于膝骨关节炎和神经系统疾病。
T21470L	Davunetide acetate Davunetide acetate(211439-12-2 Free base)	Beta Amyloid; Microtubule Associated	Cytoskeletal Signaling; Neuroscience
	Davunetide acetate 源自哺乳动物 CNS 中存在的活性依赖性神经保护蛋白。 Davunetide acetate 是一种微管稳定肽，可抑制 Aβ 聚集和 Aβ 诱导的神经毒性。 Davunetide acetate 具有神经保护、神经营养和认知保护特性。
T16430	Paliroden SR 57667,SR 57667B	Others	Others
	Paliroden 是一种可口服和用于补充神经营养的非肽类化合物，能够刺激内源性神经营养素因子的合成，用于研究阿尔兹海默症和帕金森症等神经系统类疾病。
T37621	Ezeprogind disulfate	Beta Amyloid	Neuroscience
	Ezeprogind disulfate 是一种神经营养诱导剂。 Ezeprogind disulfate 针对所有神经退行性变，包括 Abeta 蛋白或 tau 蛋白。 Ezeprogind disulfate 可用于神经系统疾病相关研究，包括进行性核上性麻痹（PSP）、tau 蛋白病、阿尔茨海默病和帕金森病等。
T8779	HBT1	GluR	Neuroscience
	HBT1 是一种 AMPA 受体增强剂，可诱导脑源性神经营养因子 (BDNF) 的产生，并且在原代神经元中几乎没有激动作用。 HBT1 以谷氨酸依赖的方式与 AMPA-R 的配体结合结构域结合。
T13587	BT18	Others	Others
	BT18 是一种功能类似于胶质细胞源神经营养因子的分子模拟物。它能够影响 GDNF 家族受体 GFRα1 和 RET 受体酪氨酸激酶 RetA 的功能。
T67955	Ensaculin Anseculin	Others	Others
	Ensaculin (Anseculin) 是一种用哌嗪部分取代的新型苯并吡喃酮，在正常和人工遗忘啮齿动物的被动和条件回避范式中显示出记忆增强作用。它在NMDA 毒性模型中表现出神经保护活性，在原代培养的大鼠脑细胞中表现出神经营养作用。Ensaculin 可用于治疗痴呆。
T32859	Longanlactone	Others	Others
	Longanlactone is a natural neurotrophic agent.
T33735	NS-1231	Others	Others
	NS-1231 exhibits neurotrophic-like effects in vitro and in vivo.
T34778	Talaumidin	Others	Others
	Talaumidin is a natural neurotrophic agent which promotes neurite outgrowth from neurons through the PI3K/Akt pathway.
TP2444	Acth (7-16)NH2 ACTH - (7-16)-amide
	Acth (7-16)NH2 exhibits neurotrophic effects.
TP2228	C3bot(154-182) C3bot (154-182)	Others	Others
	transferase-deficient neurotrophic fragment of clostridial C3 protein
T33820	ORG 2766 ORG-2766,ORG2766	Others	Others
	ORG 2766 is an ACTH 4-9 (H-Met(O)-Glu-His-Phe-D-Lys-Phe-OH) analog and neurotrophic peptide.
T32658	Leteprinim potassium SPI-205,AIT-082,SPI 205,AIT082,AIT 082,SPI205	Others	Others
	Leplinine (AIT-082, SPI-205) is a neurotrophic agent that may be used to treat Alzheimer's disease and spinal cord injury.
T82068	Inonophenol C	Others	Others
	Inonophenol C 作为一种神经营养剂，具有防治神经退行性疾病的保护作用。
T63346	TRK-IN-18	Others	Others
	TRK-IN-18 是 TRK 的有效抑制剂。其中原肌球蛋白相关激酶 (Trks) 是一种受体酪氨酸激酶家族，由神经营养因子激活，神经营养因子是一组可溶性生长因子，包含神经生长因子 (NGF)、脑源性神经营养因子 (BDNF) 和神经营养因子-3 (NT-3)，以及神经营养因子-4/5 (NT-4/5)。TRK-IN-18 表现出对癌症疾病的研究潜力。
T62561	TRK-IN-17	Others	Others
	TRK-IN-17 是一种 TRK 的有效抑制剂。其中原肌球蛋白相关激酶 (Trks) 是受体酪氨酸激酶家族成员，由神经营养因子激活。神经营养因子是一组可溶性生长因子，包括神经生长因子 (NGF)、脑源性神经营养因子 (BDNF) 和神经营养因子-3 (NT-3)，以及神经营养因子-4/5 (NT-4/5)。TRK-IN-17 具有潜力进行癌症疾病的研究。
T26993	CGP 56999A CGP56999A,CGP-56999A	Others	Others
	CGP 56999A is an antagonist of GABA(B) receptor, it enhances expression of brain-derived neurotrophic factor and attenuates dopamine depletion in the rat corpus striatum.
T33166	Majucin	Others	Others
	Majucin is a sesquiterpene derived from Illicium sp. that possess complex caged chemical architecture and remarkable neurotrophic activities with potential activity against neurodegenerative diseases.
T29543	ACAF4 ACAF-4,ACAF 4	Others	Others
	ACAF4 is a neurotrophic agent which significantly increases survival in PC12 neuronal cells and enhances the effect of nerve growth factor (NGF). ACAF4 induces neurite outgrowth, and modulates ERK1/2 and AKT signaling pathways.
T70064	PDE1-IN-1	Others	Others
	PDE1-IN-1can enhance levels of the second messengers cAMP/cGMP leading to the expression of neuronal plasticity-related genes, neurotrophic factors, and neuroprotective molecules. These neuronal plasticity enhancement properties make PDE1 inhibitors good candidates as therapeutic agents in many neurological conditions.
T40701	Ezeprogind AZP-2006	Others	Others
	Ezeprogind (AZP-2006) is an orally active neurotrophic inducer that effectively addresses the underlying factors contributing to neurodegeneration, with a broad scope extending beyond the conventional targets like Abeta protein and tau protein. Exhibiting potent neuroprotective properties, Ezeprogind is a valuable tool for studying a range of neurological disorders, including progressive supranuclear palsy (PSP), tauopathies, Alzheimer's disease, Parkinson's disease, and others.
T60243	Glycyl-L-glutamic acid
	Glycyl-L-glutamic acid 是一种体内神经营养因子 (NF)，发挥维持 AChE 含量和活性的作用。Glycyl-L-glutamic acid 不直接作用于 AChE 的合成，可能具有防止神经节前神经元退变的作用。
T37167	Reduced Haloperidol	Others	Others
	Reduced haloperidol is an active metabolite of haloperidol . It is formed via reduction of haloperidol by ketone reductase. Reduced haloperidol inhibits radioligand binding to sigma-1 and dopamine D2 receptors (Kis = 1.4 and 31 nM, respectively) and stimulates brain-derived neurotrophic factor (BDNF) secretion from CCF-SSTG1 and U87MG astrocytic glial cells. It also inhibits norepinephrine, dopamine, and serotonin (5-HT) reuptake (Kis = 21, 25, and 33 μM, respectively, in COS-7 cells expressing ...
T71576	SIM010603	Others	Others
	SIM010603 is a structurally novel, oral, multi-targeted receptor tyrosine kinase inhibitor. SIM010603 inhibited stem cell factor receptor (Kit), vascular endothelial growth factor receptor-2 (VEGFR-2), platelet-derived growth factor receptor-β (PDGFR-β), glial cell line-derived neurotrophic factor receptor (Rearranged during Transfection; RET), and Fms-like tyrosine kinase-3 (FLT3) with IC(50) values between 5.0 and 68.1 nmol/l. SIM010603 inhibited the phosphorylation of PDGFR-β and VEGFR-2. Mor...
T27269	Ensaculin HCl KA 672,KA672,Ensaculin,Anseculin Hydrochloride,KA-672 HCl	Others	Others
	Ensaculin is a NMDA antagonist and a 5HT1A agonist potentially for the treatment of Alzheimer's disease (AD). Ensaculin showed memory-enhancing effects in paradigms of passive and conditioned avoidance in both normal and artificially amnesic rodents. It e
T72227	PI3K/Akt/CREB activator 1	Others	Others
	PI3K/Akt/CREB activator 1 是一种口服有效的PI3K/Akt/CREB 的激活剂。PI3K/Akt/CREB activator 1 通过 PI3K/Akt/CREB 通路上调脑源性神经营养因子，促进神经元增殖，诱导 Neuro-2a 细胞分化成神经元样形态，加速海马原代神经元轴突-树突极化的建立。PI3K/Akt/CREB activator 1 可用于血管性痴呆 (VaD) 的研究。
T81571	PACAP (1-38) free acid TFA
	PACAP (1-38) free acid TFA，一种内源性神经肽，能有效促进胃窦运动，增强体液蛋白分泌，同时抑制胃泌素释放。此外，它刺激血管活性肠肽、胃泌素释放肽和P物质的释放，并通过RACK1增强N-甲基-D-天门冬氨酸受体功能及脑源性神经营养因子表达。
T81572	PACAP (1-38) free acid
	PACAP (1-38) free acid 是一种具有多重生物功能的内源性神经肽，主要作用包括刺激胃窦运动、增进体液蛋白分泌、抑制胃泌素分泌，以及促进血管活性肠肽、胃泌素释放肽和P 物质的释放。此外，PACAP (1-38) free acid 通过与RACK1互作，可以增强N-甲基-D-天门冬氨酸受体的功能并促进脑源性神经营养因子的表达。
T36110	L-Pyrohomoglutamic Acid	Others	Others
	L-Pyrohomoglutamic acid is an amino acid building block.1,2It has been used in the synthesis of ligands for FK506-binding proteins (FKBPs) and histone deacetylase (HDAC) inhibitors. 1.Pomplun, S., Wang, Y., Kirschner, A., et al.Rational design and asymmetric synthesis of potent and neurotrophic ligands for FK506-binding proteins (FKBPs)Angew. Chem. Int. Ed.54(1)345-348(2015) 2.Taddei, M., Cini, E., Giannotti, L., et al.Lactam based 7-amino suberoylamide hydroxamic acids as potent HDAC inhibitors...

化合物

Cat.No: T0084

Synonym: 吗氯贝胺,Ro111163

Target: MAO, Monoamine Oxidase

Cat.No: T34114

Synonym: BRN 6006446,Posatirelinum,BRN-6006446,RGH-2202,BRN6006446

Target: AChR

Cat.No: T7568

Target: Trk receptor

Edonerpic maleate

Cat.No: T4422

Synonym: T-817MA,T-817 maleate

Target: Beta Amyloid

NSI-189 Phosphate

Cat.No: T21244

Synonym: NSI189 Phosphate,NSI 189 Phosphate,NSI-189磷酸盐

Target: Others

Cat.No: T13684

Synonym: 7-Dehydroestrone

Target: Calcium Channel

Cat.No: T10624

Target: c-RET

Cat.No: T77092

Synonym: REGN-5069

Target: Others

Davunetide acetate

Cat.No: T21470L

Synonym: Davunetide acetate(211439-12-2 Free base)

Target: Beta Amyloid, Microtubule Associated

Cat.No: T16430

Synonym: SR 57667,SR 57667B

Target: Others

Ezeprogind disulfate

Cat.No: T37621

Target: Beta Amyloid

Cat.No: T8779

Target: GluR

Cat.No: T13587

Target: Others

Cat.No: T67955

Synonym: Anseculin

Target: Others

Cat.No: T32859

Target: Others

Cat.No: T33735

Target: Others

Cat.No: T34778

Target: Others

Cat.No: TP2444

Synonym: ACTH - (7-16)-amide

Cat.No: TP2228

Synonym: C3bot (154-182)

Target: Others

Cat.No: T33820

Synonym: ORG-2766,ORG2766

Target: Others

Leteprinim potassium

Cat.No: T32658

Synonym: SPI-205,AIT-082,SPI 205,AIT082,AIT 082,SPI205

Target: Others

Cat.No: T82068

Target: Others

Cat.No: T63346

Target: Others

Cat.No: T62561

Target: Others

Cat.No: T26993

Synonym: CGP56999A,CGP-56999A

Target: Others

Cat.No: T33166

Target: Others

Cat.No: T29543

Synonym: ACAF-4,ACAF 4

Target: Others

Cat.No: T70064

Target: Others

Cat.No: T40701

Synonym: AZP-2006

Target: Others

Glycyl-L-glutamic acid

Cat.No: T60243

Reduced Haloperidol

Cat.No: T37167

Target: Others

Cat.No: T71576

Target: Others

Cat.No: T27269

Synonym: KA 672,KA672,Ensaculin,Anseculin Hydrochloride,KA-672 HCl

Target: Others

PI3K/Akt/CREB activator 1

Cat.No: T72227

Target: Others

PACAP (1-38) free acid TFA

Cat.No: T81571

PACAP (1-38) free acid

Cat.No: T81572

L-Pyrohomoglutamic Acid

Cat.No: T36110

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
TN2883	3',4'-Dimethoxyflavone	Others; PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair; Others
	3',4'-Dimethoxyflavone 是类黄酮化合物的参考标准，类黄酮化合物具有多种药用活性。
T4779	4-Methylcatechol p-Methylcatechol,3,4-二羟基甲苯,Homocatechol,4-methylbenzene-1,2-diol,3,4-Dihydroxytoluene	Others; Endogenous Metabolite	Metabolism; Others
	4-Methylcatechol (3,4-Dihydroxytoluene) 是 p-toluate 的代谢物，它是 Catechol 2,3-Dioxygenase 的自杀性底物抑制剂。
TN4114	Gardenin A	ERK; LDL; MAPK; PKA; PKC	Chromatin/Epigenetic; Cytoskeletal Signaling; MAPK; Metabolism; Tyrosine Kinase/Adaptors
	Gardenin A 通过激活 MAPK/ERK、PKC 和 PKA 表现出神经营养作用。 Gardenin A 具有抗抑郁、抗惊厥和抗焦虑作用。
T29963	Americanol A
	Americanol A enhances choline acetyltransferase activity; has neurotrophic properties.
T4954L	Smilagenin PYM50028,Cogane,AI3-44895,PYM 50028
	Smilagenin is an orally active inducer of nonpeptide neurotrophic factor. It also prevents and reverses neuronal damage induced by MPP+ in mesencephalic neurons, and by MPTP in a mouse model of Parkinson's disease.
T82444	Erinacine U
	Erinacine U, a cyanhydrin diterpene isolated from Hericium erinaceus, exhibits neurotrophic activity and notably promotes neurite outgrowth in PC12 cells.
TN4123	Gelsemiol	Others	Others
	Gelsemiol has neurotrophic factor-potentiating activity, markedly enhances an increase in the proportion of neurite-bearing cells and an extension of the neurite length in the presence of nerve growth factor.
TN1798	Isorosmanol 异迷迭香酚	Beta Amyloid; AChR	Neuroscience
	Isorosmanol 具有抗氧化、神经保护和神经营养作用，可能用于老年性疾病，如认知功能下降和色素沉着。
TN5682	2,6,4'-Trihydroxy-4-methoxybenzophenone
	2,6,4'-Trihydroxy-4-methoxybenzophenone shows weak inhibitory activity of testosterone 5alpha-reductase, it also shows significant inhibition of pancreatic lipase activity. 2,6,4'-Trihydroxy-4-methoxybenzophenone has neurotrophic activity, it induced neurite outgrowth in PC-12 cells at concentration of 50 microg/ml. 2,6,4â²-Trihydroxy-4-methoxybenzophenone exhibits low cytotoxic effect against HeLa and 3T3 cell lines with IC50 values of 132 ug/ml and 158 ug/ml, repectively. It also shows antiox...
TN4291	Isofuranodiene	IL Receptor; NOS	Immunology/Inflammation
	Isofuranodiene protects GalN/LPS-induced liver injury in SD rats, it may be a potential functional food ingredient for the prevention and treatment of liver diseases. Isofuranodiene has anticancer activity, by inhibiting the proliferation and inducing apo

天然产物

3',4'-Dimethoxyflavone

Cat.No: TN2883

Target: Others, PARP

4-Methylcatechol

Cat.No: T4779

Synonym: p-Methylcatechol,3,4-二羟基甲苯,Homocatechol,4-methylbenzene-1,2-diol,3,4-Dihydroxytoluene

Target: Others, Endogenous Metabolite

Cat.No: TN4114

Target: ERK, LDL, MAPK, PKA, PKC

Cat.No: T29963

Cat.No: T4954L

Synonym: PYM50028,Cogane,AI3-44895,PYM 50028

Cat.No: T82444

Cat.No: TN4123

Target: Others

Cat.No: TN1798

Synonym: 异迷迭香酚

Target: Beta Amyloid, AChR

2,6,4'-Trihydroxy-4-methoxybenzophenone

Cat.No: TN5682

Cat.No: TN4291

Target: IL Receptor, NOS

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01864	CNTF Protein, Human, Recombinant (His) ciliary neurotrophic factor,HCNTF	Human	E. coli
	CNTF Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 24.5 kDa and the accession number is P26441.
TMPY-05510	BDNF Protein, Mouse, Recombinant (His) brain-derived neurotrophic factor	Mouse	HEK293 Cells
	BDNF is a member of thenerve growth factorfamily. It is highly expressed in hippocampus, amygdala, cerebral cortex and cerebellum. It also can be detected in heart, lung, skeletal muscle, testis, prostate and placenta. BDNF is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. During development, BDNF promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. It participates in axonal growth,...
TMPJ-00135	BDNF Protein, Human/Murine/Rat, Recombinant BDNF,Abrineurin,Brain-Derived Neurotrophic Factor	Human,Mouse,Rat	E. coli
	Brain-Derived Neurotrophic Factor (BDNF) is a member of the neurotrophin family. Along with other structurally related neurotrophic factors NGF, NT-3 and NT-4, BDNF binds with high affinity to the TrkB kinase receptor. It also binds with the LNGFR (for low-affinity nerve growth factor receptor, also known as p75). BDNF promotes the survival, growth and differentiation of neurons. It serves as a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. ...
TMPY-01678	ARMET/MANF Protein, Human, Recombinant (His) ARMET,mesencephalic astrocyte-derived neurotrophic ...	Human	HEK293 Cells
	ARMET/MANF Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20 kDa and the accession number is P55145.
TMPY-02231	TrkB Protein, Mouse, Recombinant (His) trk-B,neurotrophic tyrosine kinase, receptor, type ...	Mouse	HEK293 Cells
	TrkB Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46 kDa and the accession number is P15209-2.
TMPY-00751	TrkB Protein, Human, Recombinant (His) trk-B,GP145-TrkB/GP95-TrkB,neurotrophic tyrosine ki...	Human	HEK293 Cells
	TrkB Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.7 kDa and the accession number is Q16620-2.
TMPY-01084	TrkA Protein, Human, Recombinant (His) TRK1,TRK,TRKA,neurotrophic tyrosine kinase, recepto...	Human	HEK293 Cells
	TrkA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.5 kDa and the accession number is P04629-1.
TMPY-02792	GDNF Protein, Human, Recombinant (HEK293) HSCR3,ATF2,HFB1-GDNF,ATF1,glial cell derived neurotrophi...	Human	HEK293 Cells
	GDNF Protein, Human, Recombinant (HEK293) is expressed in HEK293 mammalian cells. The predicted molecular weight is 15.1 kDa and the accession number is P39905-2.
TMPY-02195	CNTF Protein, Rat, Recombinant ciliary neurotrophic factor	Rat	E. coli
	CNTF Protein, Rat, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 22.9 kDa and the accession number is P20294.
TMPY-02008	CNTFR Protein, Rat, Recombinant (His) ciliary neurotrophic factor receptor	Rat	Baculovirus Insect Cells
	CNTFR Protein, Rat, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 39.6 kDa and the accession number is Q08406-1.
TMPY-00523	CNTF Protein, Mouse, Recombinant (His) AI429687,ciliary neurotrophic factor	Mouse	E. coli
	CNTF Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 24.7 kDa and the accession number is P51642.
TMPY-01354	CNTFR Protein, Human, Recombinant (His) ciliary neurotrophic factor receptor	Human	Baculovirus Insect Cells
	CNTFR Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 36 kDa and the accession number is P26992.
TMPJ-00081	CNTF Protein, Human, Recombinant CNTF,Ciliary Neurotrophic Factor	Human	E. coli
	Ciliary Neurotrophic Factor (CNTF) is a potent survival factor for neurons and oligodendrocytes. CNTF has also been shown to prevent the degeneration of motor axons after axotomy. CNTF is highly conserved across species and exhibits cross-species activities. Human and rat CNTF share approximately 83% homology in their protein sequence. CNTF is structurally related to IL6, IL11, LIF and OSM. All of these four helix bundle cytokines share gp130 as a signal transducing subunit in their receptor com...
TMPY-00568	CDNF Protein, Human, Recombinant (His) cerebral dopamine neurotrophic factor,ARMETL1	Human	HEK293 Cells
	CDNF Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20 kDa and the accession number is Q49AH0-1.
TMPY-01916	CDNF Protein, Mouse, Recombinant (His) Armetl1,cerebral dopamine neurotrophic factor,93301...	Mouse	HEK293 Cells
	CDNF Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20 kDa and the accession number is Q8CC36.
TMPY-02917	TrkB Protein, Rat, Recombinant (hFc) neurotrophic tyrosine kinase, receptor, type 2	Rat	HEK293 Cells
	TrkB Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 71.5 kDa and the accession number is Q63604-1.
TMPY-03711	TrkA Protein, Canine, Recombinant (hFc) neurotrophic tyrosine kinase, receptor, type 1	Canine	HEK293 Cells
	TrkA Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.3 kDa and the accession number is XP_851619.3.
TMPY-06967	TrkA Protein, Cynomolgus, Recombinant (His) neurotrophic tyrosine kinase, receptor, type 1	Cynomolgus	HEK293 Cells
	TrkA Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.95 kDa and the accession number is XP_005541454.3.
TMPY-00188	CDNF Protein, Human, Recombinant (hFc) cerebral dopamine neurotrophic factor,ARMETL1	Human	HEK293 Cells
	CDNF Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.2 kDa and the accession number is Q49AH0-1.
TMPY-04663	TrkA Protein, Rabbit, Recombinant (His) neurotrophic tyrosine kinase, receptor, type 1	Rabbit	HEK293 Cells
	TrkA Protein, Rabbit, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.4 kDa and the accession number is XP_008262512.1.
TMPY-03635	TrkB Protein, Canine, Recombinant (His) neurotrophic tyrosine kinase, receptor, type 2	Canine	HEK293 Cells
	TrkB Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.7 kDa and the accession number is XP_541264.2.
TMPY-04285	TrkA Protein, Rat, Recombinant (His) neurotrophic tyrosine kinase, receptor, type 1	Rat	HEK293 Cells
	TrkA Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.7 kDa and the accession number is A6J617.
TMPJ-00134	pro-BDNF Protein, Human, Recombinant Brain-Derived Neurotrophic Factor,Abrineurin,BDNF	Human	E. coli
	The precursor form of Brain-Derived Neurotrophic Factor (pro-BDNF) interacts preferentially with the pan-neurotrophin receptor p75 (p75NTR) and vps10p domain-containing receptor sortilin and induces neuronal apoptosis, whereas mature BDNF selectively binds with high affinity to the TrkB kinase receptor and promotes the survival, growth and differentiation of neurons. As proneurotrophins and mature neurotrophins elicit opposite biological effects, Pro-BDNF cleavage in the neuronal system is regul...
TMPY-00228	TrkB Protein, Canine, Recombinant (hFc) neurotrophic tyrosine kinase, receptor, type 2	Canine	HEK293 Cells
	TrkB Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 71.2 kDa and the accession number is XP_541264.2.
TMPY-03162	TrkB Protein, Rat, Recombinant (His) neurotrophic tyrosine kinase, receptor, type 2	Rat	HEK293 Cells
	TrkB Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47.1 kDa and the accession number is Q63604.
TMPY-03560	TrkA Protein, Rat, Recombinant (hFc) neurotrophic tyrosine kinase, receptor, type 1	Rat	HEK293 Cells
	TrkA Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 69.2 kDa and the accession number is P35739.
TMPY-03712	TrkA Protein, Canine, Recombinant (His) neurotrophic tyrosine kinase, receptor, type 1	Canine	HEK293 Cells
	TrkA Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.2 kDa and the accession number is XP_851619.3.
TMPY-00028	ARMET/MANF Protein, Human, Recombinant (hFc) ARP,ARMET,mesencephalic astrocyte-derived neurotrophic	Human	HEK293 Cells
	ARMET/MANF Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44.9 kDa and the accession number is A8K878.
TMPH-03251	BDNF Protein, Rat, Recombinant (His) Brain-derived neurotrophic factor,BDNF	Rat	E. coli
	BDNF Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 16.3 kDa and the accession number is P23363.
TMPY-00945	TrkC Protein, Human, Recombinant (His) TRKC,gp145(trkC),neurotrophic tyrosine kinase, rece...	Human	HEK293 Cells
	TrkC Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.1 kDa and the accession number is Q16288-2.
TMPY-00944	TrkC Protein, Human, Recombinant (His & hFc) TRKC,neurotrophic tyrosine kinase, receptor, type 3...	Human	HEK293 Cells
	TrkC Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 72.5 kDa and the accession number is Q16288-2.
TMPY-01223	TrkC Protein, Mouse, Recombinant (His) TrkC,Ntrk3_tv3,AW125844,neurotrophic tyrosine kinas...	Mouse	HEK293 Cells
	TrkC Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.1 kDa and the accession number is Q6VNS1-1.
TMPY-03536	TrkA Protein, Mouse, Recombinant (His) neurotrophic tyrosine kinase, receptor, type 1,trk,...	Mouse	HEK293 Cells
	TrkA Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.7 kDa and the accession number is Q3UFB7.
TMPY-04535	GDNF Protein, Canine, Recombinant (hFc) glial cell derived neurotrophic factor,胶质细胞生长因子	Canine	HEK293 Cells
	GDNF Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40 kDa and the accession number is XP_005619436.1.
TMPY-02911	GDNF Protein, Rat, Recombinant (His) glial cell derived neurotrophic factor,胶质细胞生长因子	Rat	Baculovirus Insect Cells
	GDNF Protein, Rat, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 17.1 kDa and the accession number is Q07731-1.
TMPH-01769	Neurotrophin 3 Protein, Human, Recombinant (His) NTF3,HDNF,Neurotrophic factor,Neurotrophin-3,Nerve ...	Human	E. coli
	Seems to promote the survival of visceral and proprioceptive sensory neurons. Neurotrophin 3 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 17.7 kDa and the accession number is P20783.
TMPY-03470	TrkA Protein, Mouse, Recombinant (hFc) TrkA,C80751,neurotrophic tyrosine kinase, receptor,...	Mouse	HEK293 Cells
	TrkA Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 69.2 kDa and the accession number is Q3UFB7.
TMPH-01381	GDNF Protein, Human, Recombinant (His & SUMO) Astrocyte-derived trophic factor,GDNF,Glial cell line-derive...	Human	E. coli
	Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake. GDNF Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 31.1 kDa and the accession number is P39905.
TMPH-03341	Neurotrophin 3 Protein, Rat, Recombinant (His & Myc) Neurotrophin-3,Neurotrophic factor,Nerve growth fac...	Rat	E. coli
	Seems to promote the survival of visceral and proprioceptive sensory neurons. Neurotrophin 3 Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 21.1 kDa and the accession number is P18280.
TMPJ-00290	GFR Alpha-2/GFRA2 Protein, Human, Recombinant (hFc & His) TRNR2,GDNFR-beta,TGF-β-related neurotrophic factor ...	Human	HEK293 Cells
	GDNF family receptor alpha-2 is a glycosylphosphatidylinosito l (GPI)-linked cell surface receptor. It is part of the GDNF receptor family. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. GFRA2 mediates the NRTN-induced autophosphorylation and activation of the RET receptor. It also able to mediate GDNF signaling through the RET tyrosine kina...
TMPY-01760	TrkA Protein, Human, Recombinant (aa 194-413, His) neurotrophic tyrosine kinase, receptor, type 1,MTC,...	Human	HEK293 Cells
	TrkA Protein, Human, Recombinant (aa 194-413, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26 kDa and the accession number is P04629-1.
TMPY-01083	TrkA Protein, Human, Recombinant (His & hFc) TRKA,p140-TrkA,MTC,Trk-A,TRK1,TRK,neurotrophic tyro...	Human	HEK293 Cells
	TrkA Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 66 kDa and the accession number is P04629-1.
TMPY-06970	GDNF Protein, Human, Recombinant ATF1,ATF2,HSCR3,胶质细胞生长因子,HFB1-GDNF,glial cell derived ne...	Human	E. coli
	GDNF Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15.2 kDa and the accession number is P39905-1.
TMPY-01759	TrkA Protein, Human, Recombinant (aa 285-413, His) neurotrophic tyrosine kinase, receptor, type 1,p140...	Human	E. coli
	TrkA Protein, Human, Recombinant (aa 285-413, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 15.1 kDa and the accession number is P04629-1.
TMPY-05509	TrkB Protein, Human, Recombinant (hFc) GP145-TrkB/GP95-TrkB,trk-B,neurotrophic tyrosine ki...	Human	HEK293 Cells
	TrkB Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 70.9 kDa and the accession number is Q16620-2.
TMPY-02732	ARMET/MANF Protein, Mouse, Recombinant (His) AA408789,AA673178,D17914,D18Mgi17,mesencephalic astrocyte-de...	Mouse	HEK293 Cells
	ARMET/MANF Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.6 kDa and the accession number is Q9CXI5.
TMPJ-01469	NGF Protein, Human, Recombinant (E. colli) NGFB,神经生长因子,β-NGF,NGF,Beta-Nerve Growth Factor,β-Nerve Growt...	Mouse	E. coli
	NGF is the first member discovered in the Neurotrophin family, which includes brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), and neurotrophin-4 (NT-4). These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. Mouse beta -NGF is a homodimer of two 120 amino acid polypeptides. It shares approximately 90% homology at the amino acid level with human beta -NGF and 95.8% with rat beta -NGF. NGF signaling has been shown to play an impo...
TMPJ-00842	FGF-2 Protein, Rat, Recombinant bFGF,Heparin-Binding Growth Factor 2,FGFB,Fibroblast Growth ...	Rat	E. coli
	FGF-basic is a members of the Fibroblast Growth Factors (FGFs) family. The family constitutes a large family of proteins involved in many aspects of development including cell proliferation, growth, and differentiation. They act on several cell types to regulate diverse physiologic functions including angiogenesis, cell growth, pattern formation, embryonic development, metabolic regulation, cell migration, neurotrophic effects, and tissue repair. FGF-basic is a non-glycosylated heparin binding g...
TMPY-04069	Neurotrophin 3 Protein, Human, Recombinant NGF2,HDNF,NT-3,neurotrophin 3,NGF-2,NT3	Human	E. coli
	NTF3 (Neurotrophin 3) is a Protein Coding gene. The protein encoded by this gene is a member of the neurotrophin family, that controls the survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. NTF3 is a key mediator of neuronal development during the early neurogenic period. NTF3 is a novel target gene of POU3F2 and that the POU3F2/NTF3 pathway plays a role in the process of neuronal differentiation. ...
TMPJ-00412	VEGFR1/FLT-1 Protein, Human, Recombinant (hFc) Vascular endothelial growth factor receptor 1,Vascular perme...	Human	HEK293 Cells
	Human Vascular endothelial growth factor receptor 1(VEGFR-1, FLT-1) is a member of the the class III subfamily of receptor tyrosine kinases (RTKs) and Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 is widely expressed in human tissues including normal lung, placenta, liver, kidney, heart and brain tissues. It is specifically expressed in most of the vascular endothelial cellsand peripheral blood monocytes. VEGFR-1 contains seven Ig-like C2-type domains and one protein kinas...
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重组蛋白

CNTF Protein, Human, Recombinant (His)

Cat.No: TMPY-01864

Species: Human

Expression System: E. coli

BDNF Protein, Mouse, Recombinant (His)

Cat.No: TMPY-05510

Species: Mouse

Expression System: HEK293 Cells

BDNF Protein, Human/Murine/Rat, Recombinant

Cat.No: TMPJ-00135

Species: Human,Mouse,Rat

Expression System: E. coli

ARMET/MANF Protein, Human, Recombinant (His)

Cat.No: TMPY-01678

Species: Human

Expression System: HEK293 Cells

TrkB Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02231

Species: Mouse

Expression System: HEK293 Cells

TrkB Protein, Human, Recombinant (His)

Cat.No: TMPY-00751

Species: Human

Expression System: HEK293 Cells

TrkA Protein, Human, Recombinant (His)

Cat.No: TMPY-01084

Species: Human

Expression System: HEK293 Cells

GDNF Protein, Human, Recombinant (HEK293)

Cat.No: TMPY-02792

Species: Human

Expression System: HEK293 Cells

CNTF Protein, Rat, Recombinant

Cat.No: TMPY-02195

Species: Rat

Expression System: E. coli

CNTFR Protein, Rat, Recombinant (His)

Cat.No: TMPY-02008

Species: Rat

Expression System: Baculovirus Insect Cells

CNTF Protein, Mouse, Recombinant (His)

Cat.No: TMPY-00523

Species: Mouse

Expression System: E. coli

CNTFR Protein, Human, Recombinant (His)

Cat.No: TMPY-01354

Species: Human

Expression System: Baculovirus Insect Cells

CNTF Protein, Human, Recombinant

Cat.No: TMPJ-00081

Species: Human

Expression System: E. coli

CDNF Protein, Human, Recombinant (His)

Cat.No: TMPY-00568

Species: Human

Expression System: HEK293 Cells

CDNF Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01916

Species: Mouse

Expression System: HEK293 Cells

TrkB Protein, Rat, Recombinant (hFc)

Cat.No: TMPY-02917

Species: Rat

Expression System: HEK293 Cells

TrkA Protein, Canine, Recombinant (hFc)

Cat.No: TMPY-03711

Species: Canine

Expression System: HEK293 Cells

TrkA Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPY-06967

Species: Cynomolgus

Expression System: HEK293 Cells

CDNF Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00188

Species: Human

Expression System: HEK293 Cells

TrkA Protein, Rabbit, Recombinant (His)

Cat.No: TMPY-04663

Species: Rabbit

Expression System: HEK293 Cells

TrkB Protein, Canine, Recombinant (His)

Cat.No: TMPY-03635

Species: Canine

Expression System: HEK293 Cells

TrkA Protein, Rat, Recombinant (His)

Cat.No: TMPY-04285

Species: Rat

Expression System: HEK293 Cells

pro-BDNF Protein, Human, Recombinant

Cat.No: TMPJ-00134

Species: Human

Expression System: E. coli

TrkB Protein, Canine, Recombinant (hFc)

Cat.No: TMPY-00228

Species: Canine

Expression System: HEK293 Cells

TrkB Protein, Rat, Recombinant (His)

Cat.No: TMPY-03162

Species: Rat

Expression System: HEK293 Cells

TrkA Protein, Rat, Recombinant (hFc)

Cat.No: TMPY-03560

Species: Rat

Expression System: HEK293 Cells

TrkA Protein, Canine, Recombinant (His)

Cat.No: TMPY-03712

Species: Canine

Expression System: HEK293 Cells

ARMET/MANF Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00028

Species: Human

Expression System: HEK293 Cells

BDNF Protein, Rat, Recombinant (His)

Cat.No: TMPH-03251

Species: Rat

Expression System: E. coli

TrkC Protein, Human, Recombinant (His)

Cat.No: TMPY-00945

Species: Human

Expression System: HEK293 Cells

TrkC Protein, Human, Recombinant (His & hFc)

Cat.No: TMPY-00944

Species: Human

Expression System: HEK293 Cells

TrkC Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01223

Species: Mouse

Expression System: HEK293 Cells

TrkA Protein, Mouse, Recombinant (His)

Cat.No: TMPY-03536

Species: Mouse

Expression System: HEK293 Cells

GDNF Protein, Canine, Recombinant (hFc)

Cat.No: TMPY-04535

Species: Canine

Expression System: HEK293 Cells

GDNF Protein, Rat, Recombinant (His)

Cat.No: TMPY-02911

Species: Rat

Expression System: Baculovirus Insect Cells

Neurotrophin 3 Protein, Human, Recombinant (His)

Cat.No: TMPH-01769

Species: Human

Expression System: E. coli

TrkA Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-03470

Species: Mouse

Expression System: HEK293 Cells

GDNF Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01381

Species: Human

Expression System: E. coli

Neurotrophin 3 Protein, Rat, Recombinant (His & Myc)

Cat.No: TMPH-03341

Species: Rat

Expression System: E. coli

GFR Alpha-2/GFRA2 Protein, Human, Recombinant (hFc & His)

Cat.No: TMPJ-00290

Species: Human

Expression System: HEK293 Cells

TrkA Protein, Human, Recombinant (aa 194-413, His)

Cat.No: TMPY-01760

Species: Human

Expression System: HEK293 Cells

TrkA Protein, Human, Recombinant (His & hFc)

Cat.No: TMPY-01083

Species: Human

Expression System: HEK293 Cells

GDNF Protein, Human, Recombinant

Cat.No: TMPY-06970

Species: Human

Expression System: E. coli

TrkA Protein, Human, Recombinant (aa 285-413, His)

Cat.No: TMPY-01759

Species: Human

Expression System: E. coli

TrkB Protein, Human, Recombinant (hFc)

Cat.No: TMPY-05509

Species: Human

Expression System: HEK293 Cells

ARMET/MANF Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02732

Species: Mouse

Expression System: HEK293 Cells

NGF Protein, Human, Recombinant (E. colli)

Cat.No: TMPJ-01469

Species: Mouse

Expression System: E. coli

FGF-2 Protein, Rat, Recombinant

Cat.No: TMPJ-00842

Species: Rat

Expression System: E. coli

Neurotrophin 3 Protein, Human, Recombinant

Cat.No: TMPY-04069

Species: Human

Expression System: E. coli

VEGFR1/FLT-1 Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00412

Species: Human

Expression System: HEK293 Cells

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