|
TMPH-00010
|
MMP-14 Protein, Human, Recombinant (His & SUMO)
Membrane-type-1 matrix metalloproteinase,MMP14,Memb...
|
Human
|
E. coli
|
|
Endopeptidase that degrades various components of the extracellular matrix such as collagen. Activates progelatinase A. Essential for pericellular collagenolysis and modeling of skeletal and extraskeletal connective tissues during development. May be involved in actin cytoskeleton reorganization by cleaving PTK7. Acts as a positive regulator of cell growth and migration via activation of MMP15. Involved in the formation of the fibrovascular tissues in association with pro-MMP2. Cleaves ADGRB1 to... |
|
TMPH-02402
|
Zinc metalloproteinase Protein, Legionella pneumophila, Recombinant (His)
Zinc metalloproteinase,PEP1,PRO A
|
Legionella pneumophila
|
E. coli
|
|
Cleaves collagen, gelatin, casein, alpha-1-antitrypsin, and bovine insulin. May play a role in the pathogenesis of legionnaires disease. |
|
TMPH-03580
|
Zinc metalloproteinase aureolysin Protein, S. aureus, Recombinant (His & Myc)
Staphylococcus aureus neutral proteinase,aur,Zinc metall...
|
Staphylococcus aureus
|
E. coli
|
|
Zinc metalloproteinase aureolysin Protein, S. aureus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 40.2 kDa and the accession number is P81177. |
|
TMPH-01647
|
MMP-20 Protein, Human, Recombinant (E. coli, His & Myc)
Matrix metalloproteinase-20,Enamelysin,Enamel m...
|
Human
|
E. coli
|
|
Degrades amelogenin, the major protein component of the enamel matrix and two of the macromolecules characterizing the cartilage extracellular matrix: aggrecan and the cartilage oligomeric matrix protein (COMP). May play a central role in tooth enamel formation. Cleaves aggrecan at the '360-Asn-|-Phe-361' site. |
|
TMPH-02780
|
MMP-24 Protein, Mouse, Recombinant (His & Myc)
Matrix metalloproteinase-24,Mmp24,Membrane-type-5 m...
|
Mouse
|
E. coli
|
|
MMP-24 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli. |
|
TMPJ-00916
|
TIMP-2 Protein, Mouse, Recombinant (His)
metalloproteinase inhibitor 2,Tissue inhibitor of <...
|
Mouse
|
HEK293 Cells
|
|
Mouse Metalloproteinase inhibitor 2(TIMP-2), belongs to a family of proteins that regulate the activation and proteolytic activity of matrix metalloproteinases (MMPs). There are four mammalian members of the family; TIMP‑1, TIMP‑2, TIMP‑3, and TIMP‑4. The TIMP-2 is detected in testis, retina, hippocampus and cerebral cortex. The function of TIMP 2 protein is to inhibit MMPs non covalently by the formation of binary complexes. Complexes with metalloproteinases (such as collagenases) and irreversi... |
|
TMPH-01646
|
MMP-20 Protein, Human, Recombinant (His & Myc)
Enamel metalloproteinase,Matrix metalloproteina...
|
Human
|
Baculovirus Insect Cells
|
|
Degrades amelogenin, the major protein component of the enamel matrix and two of the macromolecules characterizing the cartilage extracellular matrix: aggrecan and the cartilage oligomeric matrix protein (COMP). May play a central role in tooth enamel formation. Cleaves aggrecan at the '360-Asn-|-Phe-361' site. |
|
TMPH-00216
|
SVMP Protein, Bothrops jararaca, Recombinant (His & KSI)
Snake venom metalloproteinase,von Willebrand factor...
|
Bothrops jararaca
|
E. coli
|
|
Metalloproteinase that binds to von Willebrand factor (VWF) and induces its interaction with GPIb (GP1BA), resulting in platelet aggregation. SVMP Protein, Bothrops jararaca, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight is 18.0 kDa and the accession number is P22028. |
|
TMPH-00217
|
SVMP Protein, Bothrops leucurus, Recombinant (His & Myc)
Snake venom metalloproteinase leucurolysin-A
|
Bothrops leucurus
|
E. coli
|
|
Non-hemorrhagic metalloproteinase that hydrolyzes the alpha chains of fibrinogen, as well as fibrin, fibronectin and casein. Beta and gamma chains are also hydrolyzed, but more slowly. Thrombolytic activity is also observed. Induces detachment of endothelial cells followed by death, and inhibits endothelial cell adhesion to fibronectin. Induces edema in mouse paw. Inhibits ADP-induced platelet aggregation on human platelet-rich plasma with an IC(50) of 2.8 uM. SVMP Protein, Bothrops leucurus, Re... |
|
TMPH-01644
|
MMP-7 Protein, Human, Recombinant (GST)
Matrix metalloproteinase-7,Uterine metalloprote...
|
Human
|
E. coli
|
|
Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase. MMP-7 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 46.1 kDa and the accession number is P09237. |
|
TMPH-03331
|
MMP-7 Protein, Rat, Recombinant (GST)
Matrin,Matrilysin,Matrix metalloproteinase-7,Uterin...
|
Rat
|
E. coli
|
|
Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase. MMP-7 Protein, Rat, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 45.9 kDa and the accession number is P50280. |
|
TMPH-02594
|
MMP-13 Protein, Mouse, Recombinant (His)
Matrix metalloproteinase-13,Collagenase 3,Mmp13
|
Mouse
|
E. coli
|
|
Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CCN2. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone develop... |
|
TMPH-01124
|
MMP-13 Protein, Human, Recombinant (His & SUMO)
Matrix metalloproteinase-13,MMP13,Collagenase 3
|
Human
|
E. coli
|
|
MMP-13 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 58.3 kDa and the accession number is P45452. |
|
TMPJ-00942
|
MMP-12 Protein, Mouse, Recombinant (His)
Mme,Mmp12,MMP-12,Mmel,Matrix metalloproteinase-12,M...
|
Mouse
|
HEK293 Cells
|
|
Matrix metalloproteinase-12（MMP12） is a secreted protein.It contains 4 hemopexin repeats and belongs to the peptidase M10A family. MMP12 may be involved in tissue injury and remodeling and have significant elastolytic activity. It can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3. |
|
TMPH-02146
|
MMP-10 Protein, Human, Recombinant (His)
Transin-2,MMP10,Matrix metalloproteinase-10,Stromel...
|
Human
|
E. coli
|
|
Can degrade fibronectin, gelatins of type I, III, IV, and V; weakly collagens III, IV, and V. Activates procollagenase. MMP-10 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 47.0 kDa and the accession number is P09238. |
|
TMPH-03166
|
Elastase Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO)
PAE,lasB,Pseudolysin,Neutral metalloproteinase,Elas...
|
Pseudomonas aeruginosa
|
E. coli
|
|
Cleaves host elastin, collagen, IgG, and several complement components as well as endogenous pro-aminopeptidase. Autocatalyses processing of its pro-peptide. Processes the pro-peptide of pro-chitin-binding protein (cbpD). Involved in the pathogenesis of P.aeruginosa infections. Elastase Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 49.1 kDa and the accession number is P14756. |
|
TMPH-01234
|
ADAM33 Protein, Human, Recombinant (His)
C20orf153,Disintegrin and metalloproteinase domain-...
|
Human
|
Baculovirus Insect Cells
|
|
ADAM33 Protein, Human, Recombinant (His) is expressed in Baculovirus with C-terminal 6xHis tag. The predicted molecular weight is 78.0 kDa. Accession number: Q9BZ11 |
|
TMPH-00448
|
SVMP Protein, Crotalus adamanteus, Recombinant (His)
Adamalysin II,Proteinase II,Snake venom metalloproteinas...
|
Crotalus adamanteus
|
E. coli
|
|
Has no significant hemorrhagic activity, but inactivates serpins by limited proteolysis of their reactive-site loops. SVMP Protein, Crotalus adamanteus, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 27.1 kDa and the accession number is P34179. |
|
TMPJ-01289
|
TIMP-4 Protein, Human, Recombinant (His)
TIMP4,TIMP-4,Metalloproteinase inhibitor 4,Tissue i...
|
Human
|
HEK293 Cells
|
|
Metalloproteinase inhibitor 4 is an enzyme that in humans is encoded by the TIMP4 gene, belongs to the protease inhibitor I35 (TIMP) family. The protein complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7 and MMP-9. |
|
TMPH-00214
|
SVMP Protein, Bothrops atrox, Recombinant (His & Myc)
Snake venom metalloproteinase atroxlysin-1,Atroxlys...
|
Bothrops atrox
|
E. coli
|
|
SVMP Protein, Bothrops atrox, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 30.4 kDa and the accession number is P85420. |
|
TMPH-02915
|
MMP-3 Protein, Mouse, Recombinant (His)
Stromelysin-1,Mmp3,Transin-1,Matrix metalloproteinase
|
Mouse
|
E. coli
|
|
Can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase. MMP-3 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 46.2 kDa and the accession number is P28862. |
|
TMPH-02145
|
MMP-3 Protein, Human, Recombinant (His & SUMO)
Transin-1,Matrix metalloproteinase-3,MMP3,Stromelys...
|
Human
|
E. coli
|
|
Can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase. |
|
TMPH-02629
|
ADAM12 Protein, Mouse, Recombinant (His & Myc)
Disintegrin and metalloproteinase domain-containing...
|
Mouse
|
Baculovirus Insect Cells
|
|
Involved in skeletal muscle regeneration, specifically at the onset of cell fusion. Also involved in macrophage-derived giant cells (MGC) and osteoclast formation from mononuclear precursors. ADAM12 Protein, Mouse, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 58.4 kDa and the accession number is Q61824. |
|
TMPH-01633
|
MMP-12 Protein, Human, Recombinant (His)
MMP12,Macrophage metalloelastase,Matrix metalloproteinas...
|
Human
|
E. coli
|
|
May be involved in tissue injury and remodeling. Has significant elastolytic activity. Can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3. MMP-12 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 46.1 kDa and the accession number is P39900. |
|
TMPJ-00101
|
TIMP-2 Protein, Human, Recombinant (His)
Tissue Inhibitor of Metalloproteinases 2,TIMP2,CSC-...
|
Human
|
HEK293 Cells
|
|
Tissue inhibitors of metalloproteinases or TIMPs are a family of proteins that regulate the activation and proteolytic activity of the zinc enzymes known as matrix metalloproteinases (MMPs). There are four members of the family, TIMP-1, TIMP-2, TIMP-3, and TIMP-4. Tissue Inhibitor of Metalloproteinases 2 (TIMP-2) is a non N-glycosylated protein with a molecular mass of 22 kDa. It produced by a wide range of cell types, which inhibits MMPs non-covalently by the formation of binary complexes and i... |
|
TMPH-02782
|
TIMP4 Protein, Mouse, Recombinant (His & SUMO)
Timp4,Metalloproteinase inhibitor 4,Tissue inhibito...
|
Mouse
|
E. coli
|
|
TIMP4 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli. |
|
TMPJ-00447
|
MMP-3 Protein, Human, Recombinant (His)
Transin-1,Stromelysin-1,MMP-3,Matrix metalloproteinase
|
Human
|
HEK293 Cells
|
|
MMP3 is a member of the matrix metalloproteinase (MMP) family whose members are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, tissue remodeling, and disease processes including arthritis and metastasis. The MMP-3 enzyme degrades collagen types II, III, IV, IX, and X, proteoglycans, fibronectin, laminin, and elastin. In addition, MMP-3 can also activate other MMPs such as MMP-1, MMP-7, and MMP-9, rendering MMP-3 c... |
|
TMPH-01665
|
TIMP3 Protein, Human, Recombinant (His)
Tissue inhibitor of metalloproteinases 3,TIMP3,Prot...
|
Human
|
E. coli
|
|
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, MMP-13, MMP-14 and MMP-15. |
|
TMPH-00866
|
ADAMTS14 Protein, Human, Recombinant (His)
A disintegrin and metalloproteinase with thrombospo...
|
Human
|
E. coli
|
|
Has aminoprocollagen type I processing activity in the absence of ADAMTS2. Seems to be synthesized as a latent enzyme that requires activation to display aminoprocollagen peptidase activity. Cleaves lysyl oxidase LOX at a site downstream of its propeptide cleavage site to produce a short LOX form. ADAMTS14 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 40.2 kDa and the accession number is Q8WXS8. |
|
TMPH-00868
|
ADAMTS7 Protein, Human, Recombinant (His & SUMO)
ADAM-TS7,ADAMTS-7,ADAM-TS 7,A disintegrin and metallopro...
|
Human
|
E. coli
|
|
Metalloprotease that may play a role in the degradation of COMP. ADAMTS7 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 52.1 kDa and the accession number is Q9UKP4. |
|
TMPJ-00957
|
MMP-9 Protein, Mouse, Recombinant (His)
Matrix metalloproteinase-9,92 kDa gelatinase,GELB,G...
|
Mouse
|
HEK293 Cells
|
|
Matrix metalloproteinases are a family of zinc and calcium dependent endopeptidases with the combined ability to degrade all the components of the extracellular matrix. MMP-9 (gelatinase B) can degrade a broad range of substrates including gelatin, collagen types IV and V, elastin and proteoglycan core protein. It is believed to act synergistically with interstitial collagenase (MMP1) in the degradation of fibrillar collagens as it degrades their denatured gelatin forms. MMP-9 is produced by ker... |
|
TMPJ-00362
|
MMP-2 Protein, Human, Recombinant (His)
72 kDa Gelatinase,TBE-1,Gelatinase A,Matrix Metalloprote...
|
Human
|
HEK293 Cells
|
|
72 kDa type IV collagenase also known as matrix metalloproteinase-2 (MMP-2) and gelatinase A is an enzyme that in humans is encoded by the MMP2 gene.It belongs to the matrix metalloproteinase (MMP) family. Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, differentiation, angiogenesis and tissue remodeling, as well as pathologic... |
|
TMPH-00867
|
ADAMTS4 Protein, Human, Recombinant (GST)
ADAMTS-14,ADAM-TS 14,A disintegrin and metalloproteinase...
|
Human
|
E. coli
|
|
Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Could also be a critical factor in the exacerbation of neurodegeneration in Alzheimer disease. Cleaves aggrecan at the '392-Glu-|-Ala-393' site. ADAMTS4 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 39.0 kDa and the accession number is O75173. |
|
TMPH-02493
|
ADAMDEC1 Protein, Mouse, Recombinant (His)
A disintegrin and metalloproteinase domain-like pro...
|
Mouse
|
E. coli
|
|
May play an important role in the control of the immune response and during pregnancy. ADAMDEC1 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 34.9 kDa and the accession number is Q9R0X2. |
|
TMPH-00869
|
ADAMTS7 Protein, Human, Recombinant (His)
ADAM-TS7,ADAM-TS 7,COMPase,ADAMTS-7,A disintegrin and me...
|
Human
|
P. pastoris (Yeast)
|
|
Metalloprotease that may play a role in the degradation of COMP. ADAMTS7 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 41.1 kDa and the accession number is Q9UKP4. |
|
TMPJ-00665
|
ADAMDEC1 Protein, Human, Recombinant (His)
a disintegrin and metalloproteinase domain-like pro...
|
Human
|
HEK293 Cells
|
|
ADAM DEC1 protein is expressed highly in the small intestine and appendix, moderately in lymph node, mucosal lining of the colon, thymus, spleen and very weakly in the bone marrow. ADAM DEC1 is induced during DC maturation and up-regulated in response to T-cell signals. It may play an important role in the control of the immune response and during pregnancy. |
|
TMPH-02485
|
ADAMTS5 Protein, Mouse, Recombinant (His)
Implantin,ADAMTS-5,ADAM-TS 5,ADMP-2,Aggrecanase-2,A disinteg...
|
Mouse
|
E. coli
|
|
ADAMTS5 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 77.8 kDa and the accession number is Q9R001. |
|
TMPH-00998
|
CD147 Protein, Human, Recombinant (aa 138-323, hFc)
HAb18G,BSG,Basigin,CD147,EMMPRIN,Extracellular matrix me...
|
Human
|
HEK293 Cells
|
|
CD147 Protein, Human, Recombinant (aa 138-323, hFc) is expressed in HEK293. |
|
TMPH-02484
|
ADAMTS13 Protein, Mouse, Recombinant (His & Myc)
ADAM-TS 1,A disintegrin and metalloproteinase with ...
|
Mouse
|
E. coli
|
|
Cleaves the vWF multimers in plasma into smaller forms thereby controlling vWF-mediated platelet thrombus formation. ADAMTS13 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 32.7 kDa and the accession number is Q769J6. |
|
TMPJ-00160
|
EMMPRIN/CD147 Protein, Human, Recombinant (His)
5F7,TCSF,OK Blood Group Antigen,Tumor Cell-Derived Collagena...
|
Human
|
HEK293 Cells
|
|
Extracellular Matrix Metalloproteinase Inducer (EMMPRIN) belongs to the immunoglobulin superfamily, which has the homology to both the immunoglobulin V domain and MHC class II antigen β-chain. EMMPRIN is a transmembrane glycoprotein with different forms, resulting from different modes of glycosylation and N-terminal sequence variants. EMMPRIN can be expressed in breast cancer, oral squamous cell carcinoma, glioma, lymphoma, lung, bladder, and melanoma carcinomas cells. EMMPRIN promotes invasion,... |
|
TMPY-05716
|
Integrin alpha V beta 3 Protein, Human, Recombinant (His)
Integrin α V β 3,Integrin alpha V β3
|
Human
|
HEK293 Cells
|
|
Integrin alpha-V & beta-3 (ITGAV/ITGB3) is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. |
|
TMPY-02869
|
MMP-12 Protein, Human, Recombinant (catalytic domain)
HME,ME,MMP-12,MME,matrix metallopeptidase 12
|
Human
|
E. coli
|
|
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, differentiation, angiogenesis, and tissue remodeling, as well as pathological processes including inflammation, arthritis, cardiovascular diseases, pulmonary diseases, and tumor invasion. Macrophage Metalloelastase, also known as Matrix metalloproteinase-12, Macrophage elastase, ... |
|
TMPK-00553
|
ADAM9 Protein, Cynomolgus, Recombinant (His)
Adam9,CORD9,mKIAA0021,Meltrin-γ,Meltrin-gamma,ADAM 9,Mltng,M...
|
Cynomolgus
|
HEK293 Cells
|
|
A disintegrin and metalloproteinase 9 (ADAM9) is a member of the transmembrane ADAM family. It is expressed in different types of solid cancer and promotes tumor invasiveness. ADAM9 may be a prognostic marker for vestibular schwannomas (VS), and ADAM9 inhibition might have the potential as a systemic approach for the treatment of VS. |
|
TMPK-01334
|
EMMPRIN/CD147 Protein, Canine, Recombinant (His)
Basigin,BSG,M6,OK,5F7,TCSF,CD147
|
Canine
|
HEK293 Cells
|
|
CD147, also known as extracellular matrix metalloproteinase inducer (EMMPRIN) or basigin, is expressed in a variety of cell types. It is involved in the regulation of extracellular matrix (ECM) remodeling during physiological and pathological processes including wound healing, inflammatory diseases, and cancer. CD147 is a diagnostic and therapeutic target in cancer and inflammatory diseases, either directly or indirectly, by targeting CD147 partners. |
|
TMPK-00933
|
ADAM8/CD156a Protein, Mouse, Recombinant (His)
CD156a,MGC134985,ADAM 8,Ms2,Adam8
|
Mouse
|
HEK293 Cells
|
|
A Disintegrin And Metalloproteinase (ADAM) proteases constitute a family of multifunctional, membrane-bound proteins with traditional sheddase functions. Their protumorigenic potential has been attributed to both, essential (ADAM10 and ADAM17) and 'dispensable' ADAM proteases (ADAM8, 9, 12, 15, and 19). Of specific interest in this review is the ADAM proteinase ADAM8 that has been identified as a significant player in aggressive malignancies including breast, pancreatic, and brain cancer. ADAM8/... |
|
TMPK-00367
|
MMP-9 Protein, Human, Recombinant (His & Avi)
MANDP2,CLG4B,Gelatinase B,GELB,MMP-9
|
Human
|
HEK293 Cells
|
|
Matrix metalloproteinase 9 (MMP9) contributes to this process and deficiencies in the MMP9 lead to impaired healing. Inappropriate expression of MMP9 also contributes to impaired re-epithelialization. Previously we demonstrated that FOXO1 was activated in wound healing but to higher levels in diabetic wounds. To address mechanisms of impaired re-epithelialization we examined MMP9 expression in vivo in full thickness dermal scalp wounds created in experimental K14. MMP-9 Protein, Human, Recombina... |
|
TMPY-04671
|
MCP-5 Protein, Mouse, Recombinant (His)
chemokine (C-C motif) ligand 12,MCP-5,Scya12,CCL12
|
Mouse
|
P. pastoris (Yeast)
|
|
Ccl12 prevented initiation of the reparative response by prolonging inflammation and inhibiting fibroblast conversion to myofibroblasts, resulting in diminished scar formation. Macrophage secretion of Ccl12 directly impaired fibronectin and collagen deposition and indirectly stimulated collagen degradation through upregulation of matrix metalloproteinase-2. In post-MI patients, circulating LPS levels strongly associated with the Ccl12 homologue monocyte chemotactic protein 1 (MCP-1). Both MCP-1 ... |
|
TMPK-00918
|
ADAM8/CD156a Protein, Human, Recombinant (aa 17-655, His)
CD156a,ADAM 8,MGC134985,Adam8,Ms2
|
Human
|
HEK293 Cells
|
|
A Disintegrin And Metalloproteinase (ADAM) proteases constitute a family of multifunctional, membrane-bound proteins with traditional sheddase functions. Their protumorigenic potential has been attributed to both, essential (ADAM10 and ADAM17) and 'dispensable' ADAM proteases (ADAM8, 9, 12, 15, and 19). Of specific interest in this review is the ADAM proteinase ADAM8 that has been identified as a significant player in aggressive malignancies including breast, pancreatic, and brain cancer. ADAM8/... |
|
TMPK-00368
|
MMP-9 Protein, Human, Recombinant (His & Avi), Biotinylated
Gelatinase B,MMP-9,MANDP2,CLG4B,GELB
|
Human
|
HEK293 Cells
|
|
Matrix metalloproteinase 9 (MMP9) contributes to this process and deficiencies in the MMP9 lead to impaired healing. Inappropriate expression of MMP9 also contributes to impaired re-epithelialization. Previously we demonstrated that FOXO1 was activated in wound healing but to higher levels in diabetic wounds. To address mechanisms of impaired re-epithelialization we examined MMP9 expression in vivo in full thickness dermal scalp wounds created in experimental K14. MMP-9 Protein, Human, Recombina... |
|
TMPK-00503
|
MMP-9 Protein, Cynomolgus, Recombinant (His)
MMP-9,CLG4B,Gelatinase B,MANDP2,GELB
|
Cynomolgus
|
HEK293 Cells
|
|
Matrix metalloproteinase 9 (MMP9) contributes to this process and deficiencies in the MMP9 lead to impaired healing. Inappropriate expression of MMP9 also contributes to impaired re-epithelialization. Previously we demonstrated that FOXO1 was activated in wound healing but to higher levels in diabetic wounds. To address mechanisms of impaired re-epithelialization we examined MMP9 expression in vivo in full thickness dermal scalp wounds created in experimental K14. MMP-9 Protein, Cynomolgus, Reco... |
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