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Anti-TIMP1 Monoclonal Antibody-PE

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产品编号 TMAZ-0042P
别名 Tissue inhibitor of metalloproteinases 1, Metalloproteinase inhibitor 1, Fibroblast collagenase inhibitor, Erythroid-potentiating activity

Anti-TIMP1 Monoclonal Antibody-PE is a Biotin-conjugated rabbit antibody targeting TIMP1. Anti-TIMP1 Monoclonal Antibody-PE can be used in ELISA, FACS, IF.

Anti-TIMP1 Monoclonal Antibody-PE

Anti-TIMP1 Monoclonal Antibody-PE

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产品编号 TMAZ-0042P 别名 Tissue inhibitor of metalloproteinases 1, Metalloproteinase inhibitor 1, Fibroblast collagenase inhibitor, Erythroid-potentiating activity

Anti-TIMP1 Monoclonal Antibody-PE is a Biotin-conjugated rabbit antibody targeting TIMP1. Anti-TIMP1 Monoclonal Antibody-PE can be used in ELISA, FACS, IF.

规格价格库存数量
25 μg¥ 3,5997日内发货
50 μg¥ 5,9987日内发货
100 μg¥ 8,9977日内发货
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产品介绍

生物活性
产品描述
Anti-TIMP1 Monoclonal Antibody-PE is a Biotin-conjugated rabbit antibody targeting TIMP1. Anti-TIMP1 Monoclonal Antibody-PE can be used in ELISA, FACS, IF.
别名Tissue inhibitor of metalloproteinases 1, Metalloproteinase inhibitor 1, Fibroblast collagenase inhibitor, Erythroid-potentiating activity
Ig Type
Rabbit monoclonal IgG
交叉反应
Human
验证活性
Flow cytometry analysis of TIMP1 overexpressed 303F cells with TMAZ-0042P, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line).
应用
ELISA, FACS, IF
推荐剂量
0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Secreted
构建方式This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of TIMP1 protein.
纯化方式Protein A Affinity Purified
性状Liquid
缓冲液0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin.
纯度> 95% as determined by SDS-PAGE.
研究背景Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. Mediates erythropoiesis in vitro; but, unlike IL3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors
偶联与修饰
偶联
PE
其他可选修饰符
Biotin/APC/AF488/AF555/AF647
可提供抗体种类
3
抗原信息
免疫原
TIMP1
抗原种属
Human
基因ID
7076
Uniprot ID
研究领域
Immunology Research
化学信息
分子量150 kDa
存储&运输
储存方式For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze.
运输方式For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice.

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