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Targets Recommended: Others

50

抑制剂 & 化合物

17

天然产物

1

化合物库

14

重组蛋白

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Cat. No. Product Name
L6130 萜类天然产物库

622 compounds
622 种萜类天然产物的独特集合,可用于高通量筛选和高内涵筛选;

化合物库

萜类天然产物库
Cat.No: L6130
Compounds: 622
Cat. No. Product Name Target Signaling Pathways
T20137 Dimethoate

Rogor,Phosphamid,Lurgo,L395,乐果,L 395,L-395

Others Others
Dimethoate (L-395) 是一种系统性和接触性杀虫剂,用于控制牛蛴螬和农场动物的某些其他害虫。
T13633 D-Phenothrin

(-)-trans-Phenothrin,右旋苯醚菊酯

Parasite Microbiology/Virology
D-Phenothrin ((-)-trans-Phenothrin) 是一种口服有效的 II 型合成拟除虫菊酯,广泛用于杀死昆虫,蚊子和人类虱子。它还用于兽医,保护农作物和控制动物上的害虫。
T16044 Methoprene

烯虫酯,ZR-515

Others Others
Methoprene (ZR-515) 是一种保幼激素模拟物和一种生物杀虫剂。Methoprene 作为昆虫生长调节剂,干扰昆虫的生命周期并阻止其成熟或繁殖。
T19940 Sulfoxaflor

GF 2372,氟啶虫胺腈,GF 2032,XDE 208

AChR Neuroscience
Sulfoxaflor (GF 2032) 是 nAChR1 和 nAChR2 亚型的激动剂,是一种作用于昆虫中枢神经系统的内吸性杀虫剂。 Sulfoxaflor 用于防治吸食汁液的昆虫,如褐飞虱、烟粉虱、桃蚜和棉蚜。
T20692L Schistoflrfamide acetate

Schistoflrfamide acetate(121801-61-4 Free base)

Others Others
Schistoflrfamide acetate 是从蚱蜢 Schistocerca gregaria 中分离得到的。 Schistoflrfamide acetate 对昆虫乳白色小管腺细胞的基底膜电位产生直接影响。
T3202 Fluensulfone

MCW-2

Parasite Microbiology/Virology
Fluensulfone (MCW-2) 是一种新型杀线虫剂,可化学防治植物寄生线虫。
T0997 Temephos

双硫磷,Temefos

AChR; Parasite Microbiology/Virology; Neuroscience
Temephos (Temefos) 是一种胆碱酯酶抑制剂,是一种有机硫代磷酸盐杀虫剂,用于治疗被携带疾病的昆虫侵染的水。
TP1571L Allatostatin II acetate(123374-34-5 free base)

Others Others
Allatostatin II acetate(123374-34-5 free base) 用于昆虫保幼激素合成抑制剂。
TP1413L Crustacean Cardioactive Peptide Acetate

CCAP acetate

Crustacean Cardioactive Peptide Acetate (CCAP acetate) 是 是节肢动物中最保守和普遍存在的神经肽,在昆虫中由腹侧神经索中的保守神经元网络产生。Crustacean Cardioactive Peptide Acetate 是一种环酰胺化九肽激素,常见于昆虫,甲壳类动物和其他节肢动物中。
TP1658L Type A Allatostatin I acetate

Type A Allatostatin I acetate(123209-95-0 free base)

Others Others
Type A Allatostatin I acetate(123209-95-0 free base) 是一种十三肽。 Allatostatin 是多效性神经肽,用于抑制昆虫保幼激素的合成。
TP1605L1 Allatostatin IV TFA(123338-13-6 free base)

Others Others
Allatostatin IV TFA(123338-13-6 free base) 是一种八肽胺,是在昆虫中发现的抑制(allatostatins)或刺激(allatotropins)保幼激素(JH)合成的调节肽家族的成员。
T2196 Fipronil

氟虫腈,Fluocyanobenpyrazole,Termidor

P450; GluCls; GABA Receptor Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Neuroscience
Fipronil (Fluocyanobenpyrazole) 是昆虫GABA 受体的选择性拮抗剂,可抑制蟑螂神经元中谷氨酸盐引起的脱敏和非脱敏。在分离的大鼠肝微粒体中,它诱导细胞色素 P450 (CYP) 亚型CYP1A1/2、CYP2B1/2和CYP3A1/2的活性。
T15775 Lotilaner

GABA Receptor; Parasite Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience
Lotilaner 是杀寄生虫剂,是非竞争性的昆虫GABACl 受体拮抗剂,对果蝇 GABA 受体的IC50值为 23.84 nM。对家犬的 GABAA 无明显作用。
T19829 Chlorfenapyr

Pylon,AC 303630,Pirate,AC-303630,AC303630,虫螨腈

Others Others
Chlorfenapyr (AC 303630) 是吡咯杀虫剂。在体内混合功能氧化酶的作用下,它可代谢为 CL 303268。它对多种昆虫具有活性,包括对拟除虫菊酯和有机磷酸盐杀虫剂敏感和具有抗性的昆虫。含 Chlorfenapyr (AC 303630) 的制剂已被用于控制白蚁,在农业中已被用于控制各种昆虫。
T0976 Propoxur

残杀威,Aprocarb,Propoxure,Baygon

AChR; Antifungal Microbiology/Virology; Neuroscience
Propoxur (Propoxure) 是一种氨基甲酸酯类杀虫剂,用于控制蟑螂、苍蝇、蚊子以及草坪和草坪昆虫。
T4139 D-Luciferin potassium

D-Luciferin K Salt,D-Luciferin Potassium Salt,D-萤光素钾盐,D-荧光素钾盐

Others Others
D-Luciferin potassium (D-Luciferin K Salt) 是一种荧光素酶 (Luc) 的底物,能够催化生物发光昆虫产生典型的黄绿光 (560 nm)。D-Luciferin potassium 可以用于荧光素酶实验。
T20785 Terallethrin

M-108,M 108,M108,Knockthrin

Others Others
Terallethrin, a pesticide, controls flying insects including houseflies, mosquitoes, and wasps.
T20195 Cartap hydrochloride

Caldan,Cartap HCl,Cartap monohydrochloride,Dihydronereistoxin dicarbamate

Others Others
Cartap hydrochloride is an insecticidal derivative. It is used to control chewing and sucking insects on many crops.
TP1571 Allatostatin II

Allatostatin II is an Inhibitors of juvenile hormone synthesis in insects.
T26671 Aspon

NSC2550,NSC-2550,NSC 2550

Others Others
Aspon is an organophosphate pesticide, it is used primarily on turf insects.
T20813 Resmethrin

Resmetrina,Benzofuroline,Isathrine

Others Others
Resmethrin, a synthetic pyrethroid insecticide, is used against a variety of insects.
T20788 Empenthrin

MA-108,S2852,S 2852,MA108,S-2852,MA 108

Others Others
Empenthrin, a synthetic pyrethroid used in insecticides, is active against broad spectrum of flying insects including moths and other pests damaging textile.
T20940 Chlorpyrifos-methyl

M-3196,M 3196

Others Others
Chlorpyrifos-methyl inhibits acetylcholinesterase by acting on the nervous system of insects.
T19750 Spinosad Factor D

Others Others
Spinosad Factor D is a naturally derived fermentation product. It is used as a pesticide against many different insects.
T39306 7-Oxodehydroabietic acid

Others Others
7-Oxodehydroabietic acid is a diterpene resin acid found in the roots of Pinus densiflora pine. It acts as a defensive compound against herbivorous insects by disrupting their endocrine system.
T38272 Thiacloprid

AChR; Parasite Microbiology/Virology; Neuroscience
Thiacloprid 属于氯烟碱类杀虫剂,主要用于防治蔬菜和果园中的蚜虫。它会破坏 DNA 的稳定性,通过疏水或氢相互作用,结合到小沟槽中,改变 DNA 的结构和稳定性。
TP1564 Destruxin A

Destruxin A is a cyclic hexadepsipeptide produced by fungus causing paralysis and death in insects.
T76183 Corazonin

Corazonin是一种在昆虫体内普遍存在的高度保守神经肽激素,主要调节社会性昆虫的等级身份和行为。它在工蜂和/或其他社会性昆虫的觅食个体中优先表达。
TP1658 Type A Allatostatin I

Type A Allatostatin I is a tridecapeptide that falls under the category of pleiotropic neuropeptides. These neuropeptides are known for their ability to inhibit the synthesis of juvenile hormone in insects.
TP1605 Allatostatin IV

Allatostatin IV, an octapeptide amine, is a member of the allatoregulatory peptide family found in insects which either inhibit (allatostatins) or stimulate (allatotropins) juvenile hormone (JH) synthesis.
T32670 Leucopterin

NSC 93740,NSC93740,NSC-93740,Leikopterin

Others Others
Leucopterin 是一种具有生物活性的蝶呤类化合物。它是芸苔蝶和其他蝴蝶翅膀中的白色色素,也可以在黄蜂和其他昆虫身上找到。
T8814 Nikkomycin Z

尼柯霉素Z,Nikkomycin Z from Streptomyces tendae,尼柯霉素 Z

Others; Antibiotic; Antifungal Microbiology/Virology; Others
Nikkomycin Z (Nikkomycin Z from Streptomyces tendae) 是一种选择性竞争性几丁质合成抑制剂。它是一种核苷肽,可作为几丁质合酶底物 UDP-N-乙酰氨基葡萄糖的竞争性类似物,具有抗真菌作用。
T37665 Endosulfan I

Others Others
Endosulfan I is an organochlorine insecticide and a stereoisomer of endosulfan II . It is active against a variety of insects, including bollworms (LD50 = 0.63 mg/g). Endosulfan I binds to GABA receptors in rat brain membranes with an IC50 value of 30 nM and is toxic to rats (LD50 = 18 mg/kg).
T19171 (9Z,​12E)​-​Tetradecadien-​1-​yl acetate

Others Others
(9Z,12E)-Tetradecadien-1-yl acetate is the main component of the pheromone of insects Plodia Interpunctella and Ephestia Kuehniella, and cereal pests.
T37921 7(Z),11(Z)-Nonacosadiene

Others Others
Unsaturated cuticular hydrocarbons serve as pheromones in insects. In D. melanogaster, these hydrocarbons are sexually dimorphic in both their occurrence and their effects. 7(Z),11(Z)-Nonacosadiene is a cuticular pheromone in female fruit flies that stimulates male courtship behavior. The biosynthesis of this C29 diene appears to be mediated by an elongase with female-based expression.
T38813 6-Azathymine acid

Others Others
6-Azathymine acid is a metabolite derived from Pymetrozine, a potent insecticide known for its effectiveness against plant-sucking insects, specifically aphids and whiteflies. Pymetrozine's neuroactivity disrupts the feeding behavior of these pests, making it a valuable tool in protecting various crops, including vegetables, cotton, field crops, and fruits.
T32849 Loline

Others Others
Loline is a natural insecticidal and deterrent to a broad range of insects, including species in the Hemiptera, Coleoptera, Hymenoptera, Lepidoptera, and Blattodea orders. Loline deters species such as the bird cherry-oat aphid (genus Rhopalosiphum), larg
T32851 Lolitrem B

Others Others
Lolitrem B is one of many toxins produced by a fungus called Epichloë festucae (var. lolii), which grows in perennial ryegrass. The fungus is symbiotic with the ryegrass; it doesn't harm the plant, and the toxins it produces kill insects that feed on ryeg
T80848 VUAA1

Others Others
VUAA1为昆虫气味辅助受体(Orco)激动剂,能够激活具Orco的异聚及同聚通道,进而干扰害虫的破坏性行为,适用于昆虫嗅觉方面的研究。
TP1413 Crustacean Cardioactive Peptide (CCAP)

Crustacean Cardioactive Peptide CCAP,甲壳类心脏活性肽

Crustacean cardioactive peptide (CCAP) is a highly conserved, amidated cyclic nonapeptide with the primary structure PFCNAFTGC-NH2 (ProPheCysAsnAlaPheTyrGlyCys-NH2) and a disulfide bridge between Cys3 and Cys9. It is found in crustaceans and insects where
T2214 Flumethrin

Others Others
Flumethrin 是一种拟除虫菊酯类杀虫剂。外用在兽药中,用于防治牛、绵羊、山羊、马和狗身上的寄生虫和蜱,以及治疗蜜蜂群中的寄生虫。
T81948 Latartoxin-1a

LtTx-1a

Latartoxin-1a (LtTx-1a) 是从L. tarabaevi中分离的肽毒素,对昆虫具备麻痹及致死效果,并显示膜结合活性。
T37920 7(Z),11(Z)-Heptacosadiene

Others Others
The mating and social behaviors of insects are largely orchestrated by a suite of volatile cuticular hydrocarbon pheromones. 7(Z),11(Z)-Heptacosadiene is the predominant female-specific courtship pheromone of the fruit fly D. melanogaster. At amounts above 100 ng, 7(Z),11(Z)-heptacosadiene elicits wing vibrations in male D. melanogaster flies in a dose-dependent manner.
T37802 Phospho-L-Arginine (lithium salt hydrate)

Others Others
Phospho-L-arginine is a phosphorylated form of L-arginine and a highly diffusible, high-energy metabolite and phosphagen involved in energy storage in invertebrates including crustaceans, insects, and Trypanosoma species. In the locust L. migratoria, phospho-L-arginine is found in the flight muscles, where it acts as both a buffer system and shuttle mechanism for high-energy phosphate. Measurement of phospho-L-arginine by 31P-NMR spectroscopy has been used to study invertebrate energy metabolism...
TP1852 Myomodulin

肌调蛋白

Others; Potassium Channel; Calcium Channel; Sodium Channel Membrane transporter/Ion channel; Metabolism; Others
Myomodulin 是一种存在于软体动物、昆虫和腹足类动物中的神经肽。它存在于两个已确定的海兔神经元中,它们包含肌调节蛋白 A、ARC 运动神经元 B16 和腹部神经元 L10。
T83165 Adipokinetic hormone (Manduca sexta)

Manse-AKH

Adipokinetic Hormone (Apis mellifera ligustica, Bombyx mori, Heliothis zea, Manduca sexta) 是昆虫肽类激素,能强烈诱导促脂肪/高海藻素反应,但不具备糖原动员功能,亦不能在脂肪体内有效储存及利用糖原。
T85258 Endosulfan II

β-Endosulfan,Endosulfan B

Others Others
Endosulfan II, an organochlorine insecticide and a stereoisomer of Endosulfan I, effectively targets various insects such as bollworms and tobacco budworms, with lethal doses (LD50s) of 4.14 and 4.95 mg/g, respectively. It interacts with GABA receptors in rat brain membranes, demonstrating an inhibition concentration (IC50) of 60 nM. Notably, Endosulfan II exhibits lower toxicity in rats compared to Endosulfan I, with LD50 values of 240 and 18 mg/kg, respectively.
T73614 Tyrosine decarboxylase

Others Others
Tyrosine decarboxylase (TDC; TyrDC),即酪氨酸脱羧酶,广泛存在于植物、昆虫和不同微生物中,常用于生化研究。Tyrosine decarboxylase 是一种5'-磷酸吡哆醛 (PLP) 依赖性脱羧酶,可以催化酪氨酸中羧基的去除,产生酪胺和二氧化碳。
T37922 7(Z),11(Z)-Pentacosadiene

Others Others
Unsaturated, long-chain hydrocarbons are found on the cuticles of insects and can act as pheromones. In mature Drosophila melanogaster, certain cuticular hydrocarbons are sexually dimorphic: males synthesize 23- and 25-C monoenes and females produce 27- and 29-C dienes. Each of these lipids plays specific roles in regulating male sexual behavior, with dienes stimulating courtship. 7(Z),11(Z)-Pentacosadiene is a 25-C hydrocarbon that is found in low abundance on cuticles of mature Drosophila fema...
T37924 7(Z)-Tricosene

Others Others
7(Z)-Tricosene is an unsaturated cuticular hydrocarbon that acts as a pheromone in some insects, including Drosophila. While it is present in both sexes of some Drosophila species, it is abundant in males, but not females, of D. melanogaster and D. sechellia. In these species, 7(Z)-tricosene prevents or reduces male courtship behavior and increases female sexual receptivity. It is absent from virgin D. melanogaster females, but is transferred from males to females during mating. In addition, mat...

化合物

Dimethoate
Cat.No: T20137
Synonym: Rogor,Phosphamid,Lurgo,L395,乐果,L 395,L-395
Target: Others
D-Phenothrin
Cat.No: T13633
Synonym: (-)-trans-Phenothrin,右旋苯醚菊酯
Target: Parasite
Methoprene
Cat.No: T16044
Synonym: 烯虫酯,ZR-515
Target: Others
Sulfoxaflor
Cat.No: T19940
Synonym: GF 2372,氟啶虫胺腈,GF 2032,XDE 208
Target: AChR
Schistoflrfamide acetate
Cat.No: T20692L
Synonym: Schistoflrfamide acetate(121801-61-4 Free base)
Target: Others
Fluensulfone
Cat.No: T3202
Synonym: MCW-2
Target: Parasite
Temephos
Cat.No: T0997
Synonym: 双硫磷,Temefos
Target: AChR, Parasite
Allatostatin II acetate(123374-34-5 free base)
Cat.No: TP1571L
Synonym:
Target: Others
Crustacean Cardioactive Peptide Acetate
Cat.No: TP1413L
Synonym: CCAP acetate
Target:
Type A Allatostatin I acetate
Cat.No: TP1658L
Synonym: Type A Allatostatin I acetate(123209-95-0 free base)
Target: Others
Allatostatin IV TFA(123338-13-6 free base)
Cat.No: TP1605L1
Synonym:
Target: Others
Fipronil
Cat.No: T2196
Synonym: 氟虫腈,Fluocyanobenpyrazole,Termidor
Target: P450, GluCls, GABA Receptor
Lotilaner
Cat.No: T15775
Synonym:
Target: GABA Receptor, Parasite
Chlorfenapyr
Cat.No: T19829
Synonym: Pylon,AC 303630,Pirate,AC-303630,AC303630,虫螨腈
Target: Others
Propoxur
Cat.No: T0976
Synonym: 残杀威,Aprocarb,Propoxure,Baygon
Target: AChR, Antifungal
D-Luciferin potassium
Cat.No: T4139
Synonym: D-Luciferin K Salt,D-Luciferin Potassium Salt,D-萤光素钾盐,D-荧光素钾盐
Target: Others
Terallethrin
Cat.No: T20785
Synonym: M-108,M 108,M108,Knockthrin
Target: Others
Cartap hydrochloride
Cat.No: T20195
Synonym: Caldan,Cartap HCl,Cartap monohydrochloride,Dihydronereistoxin dicarbamate
Target: Others
Allatostatin II
Cat.No: TP1571
Synonym:
Target:
Aspon
Cat.No: T26671
Synonym: NSC2550,NSC-2550,NSC 2550
Target: Others
Resmethrin
Cat.No: T20813
Synonym: Resmetrina,Benzofuroline,Isathrine
Target: Others
Empenthrin
Cat.No: T20788
Synonym: MA-108,S2852,S 2852,MA108,S-2852,MA 108
Target: Others
Chlorpyrifos-methyl
Cat.No: T20940
Synonym: M-3196,M 3196
Target: Others
Spinosad Factor D
Cat.No: T19750
Synonym:
Target: Others
7-Oxodehydroabietic acid
Cat.No: T39306
Synonym:
Target: Others
Thiacloprid
Cat.No: T38272
Synonym:
Target: AChR, Parasite
Destruxin A
Cat.No: TP1564
Synonym:
Target:
Corazonin
Cat.No: T76183
Synonym:
Target:
Type A Allatostatin I
Cat.No: TP1658
Synonym:
Target:
Allatostatin IV
Cat.No: TP1605
Synonym:
Target:
Leucopterin
Cat.No: T32670
Synonym: NSC 93740,NSC93740,NSC-93740,Leikopterin
Target: Others
Nikkomycin Z
Cat.No: T8814
Synonym: 尼柯霉素Z,Nikkomycin Z from Streptomyces tendae,尼柯霉素 Z
Target: Others, Antibiotic, Antifungal
Endosulfan I
Cat.No: T37665
Synonym:
Target: Others
(9Z,​12E)​-​Tetradecadien-​1-​yl acetate
Cat.No: T19171
Synonym:
Target: Others
7(Z),11(Z)-Nonacosadiene
Cat.No: T37921
Synonym:
Target: Others
6-Azathymine acid
Cat.No: T38813
Synonym:
Target: Others
Loline
Cat.No: T32849
Synonym:
Target: Others
Lolitrem B
Cat.No: T32851
Synonym:
Target: Others
VUAA1
Cat.No: T80848
Synonym:
Target: Others
Crustacean Cardioactive Peptide (CCAP)
Cat.No: TP1413
Synonym: Crustacean Cardioactive Peptide CCAP,甲壳类心脏活性肽
Target:
Flumethrin
Cat.No: T2214
Synonym:
Target: Others
Latartoxin-1a
Cat.No: T81948
Synonym: LtTx-1a
Target:
7(Z),11(Z)-Heptacosadiene
Cat.No: T37920
Synonym:
Target: Others
Phospho-L-Arginine (lithium salt hydrate)
Cat.No: T37802
Synonym:
Target: Others
Myomodulin
Cat.No: TP1852
Synonym: 肌调蛋白
Target: Others, Potassium Channel, Calcium Channel, Sodium Channel
Adipokinetic hormone (Manduca sexta)
Cat.No: T83165
Synonym: Manse-AKH
Target:
Endosulfan II
Cat.No: T85258
Synonym: β-Endosulfan,Endosulfan B
Target: Others
Tyrosine decarboxylase
Cat.No: T73614
Synonym:
Target: Others
7(Z),11(Z)-Pentacosadiene
Cat.No: T37922
Synonym:
Target: Others
7(Z)-Tricosene
Cat.No: T37924
Synonym:
Target: Others
Cat. No. Product Name Target Signaling Pathways
TN1788 Isookanin

Amylase Metabolism
Isookanin 在多种疾病领域有研究价值,包括肿瘤,皮疹,蛇和昆虫叮咬,糖尿病,腹泻。它可作为抗病毒剂对抗 HSV 和水痘带状疱疹病毒。它也具有抗氧化特性。
T22295 cis-3-Hexen-1-ol

叶醇,Leaf alcohol,(Z)-3-Hexen-1-ol

Others Others
cis-3-Hexen-1-ol ((Z)-3-Hexen-1-ol) 是发现于许多新鲜水果和蔬菜中的一种绿色草味化合物,常用作加工食品的附加风味剂,以提供新鲜的绿色品质,也是多种昆虫的引诱剂。
TN3601 Carminic acid

ROS Immunology/Inflammation
Carminic acid 是天然红色色素,是球虫染料家族中的一种。
T22291 Chitin

Chitin (From shrimp and crab shells)

Others Others
Chitin 是一种大型的结构多糖,存在于真菌的细胞壁、昆虫的外骨骼以及鱼类和无脊椎动物的某些坚硬结构中。
T5786 TETRAHYDROPIPERINE

四氢胡椒碱,Cosmoperine

P450; TRP/TRPV Channel Membrane transporter/Ion channel; Metabolism
Tetrahydropiperine (Cosmoperine) 是胡椒碱的环己基类似物,也是一种天然芳基戊酰胺,从Piper longum 分离得到。它对细胞色素 P450 (CYP) 同工型 CYP1A1/芳基烃羟化酶 (AHH;IC50=23 µM)具有抑制作用。
T3016 D-(+)-Melezitose hydrate

D-Melezitose,melicitose,Melezitose,松三糖

Others; Antibacterial Microbiology/Virology; Others
D-(+)-Melezitose hydrate (melicitose) 是由许多以植物汁液为食的昆虫通过酶反应产生的一种非还原性三糖,能鉴定吲哚阳性和吲哚阴性克雷伯菌属的临床分离株。
T2881 Crustecdysone

Commisterone,B-ecdysone,Commisterone,20-Hydroxyecdysone,Ecdysterone,B-ecdysone,β-蜕皮甾酮,Hydroxyecdysone,羟基蜕皮激素

Others; Caspase; Endogenous Metabolite; Autophagy Apoptosis; Autophagy; Metabolism; Others; Proteases/Proteasome
Crustecdysone (Hydroxyecdysone) 是来源于露水草的一种蜕皮激素,可调节昆虫的蜕皮或蜕皮过程。它是 Ecdysone 的活性代谢物,通过 20E 核受体复合物 EcR-USP 抑制半胱天冬酶活性并诱导自噬,在心血管系统中具有调节或保护作用。
T5S0527 Rhodojaponin III

闹羊花素 Ⅲ,闹羊花毒素III

Others Others
Rhodojaponin III 是二萜类化合物,提取于Rhododendron molle 叶子,具有抗炎作用。
TN1216 2-O-Acetyl-20-hydroxyecdysone

20-Hydroxyeedysone 2-acetate

Beta Amyloid; Others Neuroscience; Others
2-O-Acetyl-20-hydroxyecdysone 是存在于昆虫和陆生植物中的一种蜕皮激素,2-O-Acetyl-20-hydroxyecdysone 对 amyloid-β42 诱导的细胞毒性有抑制作用,能够通过促进纤维发生减少 Aβ 寡聚物的形成,将 Aβ 寡聚物转变为低毒性纤维。
T13641 Dehydrotomatine

Others Others
Dehydrolycopene is a major steroidal sugar alkaloid (SGAs), which is mainly found in mature green fruits, leaves and flowers of tomatoes. Dehydrotomato is targeted at bacteria, fungi, insects and animals.
T37471 Makisterone A

Others Others
Makisterone A is an ecdysteroid that drives molting in insects. It binds the heterodimeric ecdysone receptor with nanomolar affinity.
T40158 N-acetyldopamine

NADA,N-乙酰多巴胺

Others Others
N-acetyldopamine (NADA) is a catecholamine utilized by insects as a precursor for sclerotization, a process that strengthens their cuticle.
TN2490 1,3-Diacetylvilasinin

Others Others
1,3-Diacetylvilasinin shows marginal cytotoxicities against certain human tumor cell lines. It also shows antifeeding activity towards insects.
T6601 Nanchangmycin

Nanchangmycin A,南昌霉素

Antibacterial; Antibiotic Microbiology/Virology
Nanchangmycin (Nanchangmycin A) 由 Streptomyces nanchangensis 产生的一种聚醚抗生素,抑制革兰氏阳性菌。它也是一种广谱抗病毒药物,有抗 Zika 病毒作用。
T36828 9(Z)-Tricosene

Others Others
(9Z)-Tricosene is a pheromone released by insects, including D. melanogaster, M. domestica (house fly), and A. mellifera L. (honey bee). In Drosophila, it induces aggregation behavior and is an oviposition guidance cue for females. Due to its aggregation-inducing activity, it is used as a bait pesticide to attract insects to traps. The mechanism of action in Drosophila is the activation of antennal basiconic Or7a receptors. It is also highly produced by honey bees during the waggle dance, which ...
T79990 Notrilobolide

Parasite Microbiology/Virology
Notrilobolide 是一种从甘薯中分离出的生物碱,具杀虫特性。对赤拟谷盗(Tribolium castaneum)等害虫幼虫发育产生抑制效果,主要通过限制其繁殖能力来干扰昆虫消化与繁殖过程。
TN3910 Ecdysone

Apoptosis; ATPase; Glucocorticoid Receptor; Potassium Channel; Sodium Channel; Endogenous Metabolite; Autophagy Apoptosis; Autophagy; Endocrinology/Hormones; Membrane transporter/Ion channel; Metabolism
Ecdysone 是存在于昆虫和草药中的主要类固醇激素,可以激活盐皮质激素受体并诱导细胞凋亡。Ecdysone 的活性代谢物 20-羟基蜕皮激素在协调发育过渡和体内稳态睡眠调节中起重要作用。

天然产物

Isookanin
Cat.No: TN1788
Synonym:
Target: Amylase
cis-3-Hexen-1-ol
Cat.No: T22295
Synonym: 叶醇,Leaf alcohol,(Z)-3-Hexen-1-ol
Target: Others
Carminic acid
Cat.No: TN3601
Synonym:
Target: ROS
Chitin
Cat.No: T22291
Synonym: Chitin (From shrimp and crab shells)
Target: Others
TETRAHYDROPIPERINE
Cat.No: T5786
Synonym: 四氢胡椒碱,Cosmoperine
Target: P450, TRP/TRPV Channel
D-(+)-Melezitose hydrate
Cat.No: T3016
Synonym: D-Melezitose,melicitose,Melezitose,松三糖
Target: Others, Antibacterial
Crustecdysone
Cat.No: T2881
Synonym: Commisterone,B-ecdysone,Commisterone,20-Hydroxyecdysone,Ecdysterone,B-ecdysone,β-蜕皮甾酮,Hydroxyecdysone,羟基蜕皮激素
Target: Others, Caspase, Endogenous Metabolite, Autophagy
Rhodojaponin III
Cat.No: T5S0527
Synonym: 闹羊花素 Ⅲ,闹羊花毒素III
Target: Others
2-O-Acetyl-20-hydroxyecdysone
Cat.No: TN1216
Synonym: 20-Hydroxyeedysone 2-acetate
Target: Beta Amyloid, Others
Dehydrotomatine
Cat.No: T13641
Synonym:
Target: Others
Makisterone A
Cat.No: T37471
Synonym:
Target: Others
N-acetyldopamine
Cat.No: T40158
Synonym: NADA,N-乙酰多巴胺
Target: Others
1,3-Diacetylvilasinin
Cat.No: TN2490
Synonym:
Target: Others
Nanchangmycin
Cat.No: T6601
Synonym: Nanchangmycin A,南昌霉素
Target: Antibacterial, Antibiotic
9(Z)-Tricosene
Cat.No: T36828
Synonym:
Target: Others
Notrilobolide
Cat.No: T79990
Synonym:
Target: Parasite
Ecdysone
Cat.No: TN3910
Synonym:
Target: Apoptosis, ATPase, Glucocorticoid Receptor, Potassium Channel, Sodium Channel, Endogenous Metabolite, Autophagy
Cat. No. Product Name Species Expression System
TMPH-00184 Cry1Fb Protein, Bacillus thuringiensis subsp., Recombinant (His)

cryIF(b),Crystaline entomocidal protoxin,Insecticidal delta-...

Bacillus thuringiensis subsp. morrisoni E. coli
Promotes colloidosmotic lysis by binding to the midgut epithelial cells of insects. Cry1Fb Protein, Bacillus thuringiensis subsp., Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 26.3 kDa and the accession number is O66377.
TMPH-03623 Tb2-II Protein, Tityus bahiensis, Recombinant (His & Myc)

Toxin Tb2-II,P-Mice-Ins-beta* NaTx5.4

Tityus bahiensis Baculovirus Insect Cells
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing. This toxin is active against both mammals and insects. Tb2-II Protein, Tityus bahiensis, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 10.8 kDa and the accession number is P60276.
TMPY-02311 AGO3 Protein, Human, Recombinant (His)

EIF2C3,argonaute RISC catalytic component 3

Human Baculovirus Insect Cells
Argonaute (Ago) protein family plays a key role in the RNA interference (RNAi) process in different insects including Lepidopteran. AGO3 also coexists and interacts with Armitage in the mitochondrial fraction. Furthermore, AGO3 acts in conjunction with the mitochondria-associated protein Zucchini to control the dynamic subcellular localization of Armitage between mitochondria and nuage in a Slicer-dependent fashion.
TMPH-00837 BjaIT Protein, Hottentotta judaicus, Recombinant (His & Myc)

Alpha-insect toxin BjaIT,Bj-alpha-IT

Hottentotta judaicus E. coli
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission. This toxin is active against insects (para/tipE). BjaIT Protein, Hottentotta judaicus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 14.4 kDa and the accession number is Q56TT9.
TMPH-02404 LqhaIT Protein, Leiurus hebraeus, Recombinant (His & SUMO)

Alpha-insect toxin LqhaIT,Lqh-alpha-IT

Yellow scorpion E. coli
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission. The dissociation is voltage-dependent. This toxin is active on insects. It is also highly toxic to crustaceans and has a measurable but low toxicity to mice. LqhaIT Protein, Leiurus hebraeus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 23.5 kDa and ...
TMPH-02405 LqqIT1 Protein, Leiurus quinquestriatus quinquestriatus, Recombinant (His & Myc)

Beta-insect excitatory toxin LqqIT1

Egyptian scorpion E. coli
Excitatory insect beta-toxins induce a spastic paralysis. They bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing. This toxin induces a fast excitatory contraction paralysis on fly larvae. It is active only on insects. LqqIT1 Protein, Leiurus quinquestriatus quinquestriatus, Recombinant (His & Myc) is expressed in E. coli expre...
TMPH-03624 Tb2-II Protein, Tityus bahiensis, Recombinant (E. coli, His & Myc)

Toxin Tb2-II,P-Mice-Ins-beta* NaTx5.4

Tityus bahiensis E. coli
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing. This toxin is active against both mammals and insects. Tb2-II Protein, Tityus bahiensis, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 12.0 kDa and the accession number is P...
TMPH-00056 Delta-AITX-Avd1c Protein, Anemonia sulcata, Recombinant (His)

ATX II,Delta-AITX-Avd1c,Toxin II,Delta-actitoxin-Avd1c,Neuro...

Anemonia sulcata P. pastoris (Yeast)
Binds specifically to voltage-gated sodium channels (Nav) (site 3), thereby delaying their inactivation. Has a strong effect on crustaceans and insects (DmNav1) and a weaker effect on mammals. This toxin is highly potent at mammalian Nav1.1/SCN1A (EC(50)=6.01 nM) and Nav1.2/SCN2A (EC(50)=7.88 nM). It has also great activity on Nav1.5/SCN5A (EC(50)=49.05 nM), Nav1.4/SCN4A (EC(50)=109.49 nM) and Nav1.6/SCN8A (EC(50)=about 180 nM) and is less potent on Nav1.3/SCN3A (EC(50)=759.22 nM) (when measured...
TMPJ-01034 TIM Protein, Human, Recombinant (His)

TPI1,TPI,Triose-Phosphate Isomerase,Triosephosphate Isomeras...

Human E. coli
Triose-phosphate isomerase, also named Triose-phosphate isomerase, TPI and TIM, is an enzyme that catalyzes the reversible interconversion of the triose phosphate isomers dihydroxyacetone phosphate and D-glyceraldehyde 3-phosphate. TPI has been found in nearly every organism searched for the enzyme, including animals such as mammals and insects as well as in fungi, plants, and bacteria. However, some bacteria that do not perform glycolysis, like ureaplasmas, lack TPI. TPI plays an important role...
TMPY-01306 DNMT2 Protein, Human, Recombinant (GST)

PUMET,RNMT1,tRNA aspartic acid methyltransferase 1,MHSAIIP,D...

Human Baculovirus Insect Cells
DNMT2, also known as tRNA (cytosine-5-)-methyltransferase, DNA methyltransferase homolog HsaIIP, and TRDMT1, is a member of the DNA methyltransferase family of enzymes. DNMT2 enzymes have been widely conserved during evolution and contain all of the signature motifs of DNA (cytosine-5)-methyltransferases. It contains all 10 sequence motifs that are conserved among m(5)C MTases, including the consensus S:-adenosyl-L-methionine-binding motifs and the active site ProCys dipeptide, and its structure...
TMPY-02181 PLA2G12B Protein, Mouse, Recombinant (His)

Fksg71,2010002E04Rik,Pla2g13,hlb218,phospholipase A2, group ...

Mouse HEK293 Cells
Group XIIB secretory phospholipase A2-like protein, also known as Group XIII secretory phospholipase A2-like protein, GXIII sPLA2-like, sPLA2-GXIIB, GXIIB, PLA2G13 and PLA2G12B, is a secreted protein that belongs to the phospholipase A2 family. PLA2G12B / PLA2G13 is strongly expressed in liver, small intestine and kidney. Mammalian secretory phospholipase A2s ( sPLA2s ) form a family of structurally related enzymes that are involved in a variety of physiological and pathological processes via th...
TMPY-02162 PLA2G2E Protein, Mouse, Recombinant (His)

phospholipase A2, group IIE,Phospholipase A2 IIE

Mouse HEK293 Cells
Group IIE secretory phospholipase A2, also known as GIIE sPLA2, sPLA2-IIE, Phosphatidylcholine 2-acylhydrolase 2E and PLA2G2E is a secreted protein that belongs to the phospholipase A2 family. Mammalian secretory phospholipase A2s (sPLA2s) form a family of structurally related enzymes that are involved in a variety of physiological and pathological processes via the release of arachidonic acid from membrane phospholipids or the binding to specific membrane receptors. Phospholipases A2 / PLA2 are...
TMPY-01468 Neuraminidase Protein, C.perfringens, Recombinant (His)

NP Protein

C.perfringens E. coli
Clostridium perfringens / C. perfringens (formerly known as C. welchii) is a Gram-positive, rod-shaped, anaerobic, spore-forming bacterium of the genus Clostridium. C. perfringens is ubiquitous in nature and can be found as a normal component of decaying vegetation, marine sediment, the intestinal tract of humans and other vertebrates, insects, and soil. C. perfringens is commonly encountered in infections as a benign component of the normal flora. In this case, its role in disease is min...
TMPY-02163 PGLYRP1 Protein, Mouse, Recombinant (His)

Tnfsf3l,peptidoglycan recognition protein 1,PGRP,Tasg7,Tag7,...

Mouse HEK293 Cells
Peptidoglycan recognition protein 1, also known as Peptidoglycan recognition protein short, PGRP-S, PGLYRP1, PGLYRP, PGRP and TNFSF3L, is a secreted protein that belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. PGLYRP1 / PGLYRP is highly expressed in bone marrow. It is weakly expressed in kidney, liver, small intestine, spleen, thymus, peripheral leukocyte, lung, fetal spleen and neutrophils. PGLYRP1 / PGLYRP is a pattern receptor that binds to murein peptidoglycans (PGN) of Gram-posi...

重组蛋白

Cry1Fb Protein, Bacillus thuringiensis subsp., Recombinant (His)
Cat.No: TMPH-00184
Species: Bacillus thuringiensis subsp. morrisoni
Expression System: E. coli
Tb2-II Protein, Tityus bahiensis, Recombinant (His & Myc)
Cat.No: TMPH-03623
Species: Tityus bahiensis
Expression System: Baculovirus Insect Cells
AGO3 Protein, Human, Recombinant (His)
Cat.No: TMPY-02311
Species: Human
Expression System: Baculovirus Insect Cells
BjaIT Protein, Hottentotta judaicus, Recombinant (His & Myc)
Cat.No: TMPH-00837
Species: Hottentotta judaicus
Expression System: E. coli
LqhaIT Protein, Leiurus hebraeus, Recombinant (His & SUMO)
Cat.No: TMPH-02404
Species: Yellow scorpion
Expression System: E. coli
LqqIT1 Protein, Leiurus quinquestriatus quinquestriatus, Recombinant (His & Myc)
Cat.No: TMPH-02405
Species: Egyptian scorpion
Expression System: E. coli
Tb2-II Protein, Tityus bahiensis, Recombinant (E. coli, His & Myc)
Cat.No: TMPH-03624
Species: Tityus bahiensis
Expression System: E. coli
Delta-AITX-Avd1c Protein, Anemonia sulcata, Recombinant (His)
Cat.No: TMPH-00056
Species: Anemonia sulcata
Expression System: P. pastoris (Yeast)
TIM Protein, Human, Recombinant (His)
Cat.No: TMPJ-01034
Species: Human
Expression System: E. coli
DNMT2 Protein, Human, Recombinant (GST)
Cat.No: TMPY-01306
Species: Human
Expression System: Baculovirus Insect Cells
PLA2G12B Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02181
Species: Mouse
Expression System: HEK293 Cells
PLA2G2E Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02162
Species: Mouse
Expression System: HEK293 Cells
Neuraminidase Protein, C.perfringens, Recombinant (His)
Cat.No: TMPY-01468
Species: C.perfringens
Expression System: E. coli
PGLYRP1 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02163
Species: Mouse
Expression System: HEK293 Cells
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