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Search Results for " head "

53

抑制剂 & 化合物

7

天然产物

3

化合物库

29

重组蛋白

2

同位素标记化合物

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Cat. No.	Product Name
L1000	上市药物库		2808 compounds
	2808 个上市药物化合物集合，可用于高通量筛选和高内涵筛选；
L1010	FDA上市及药典收录分子库		3158 compounds
	3158 个上市及药典分子集合，可用于高通量筛选和高内涵筛选；
DO2200	共价抑制剂库CD		12000 compounds
	数量多：超过12000种共价结合化合物，并且数量在持续增加；

化合物库

上市药物库

Cat.No: L1000

Compounds: 2808

FDA上市及药典收录分子库

Cat.No: L1010

Compounds: 3158

共价抑制剂库CD

Cat.No: DO2200

Compounds: 12000

Cat. No.	Product Name	Target	Signaling Pathways
T82221	Head activator neuropeptide
	Head activator neuropeptide 是一种源自哺乳动物细胞系的神经元或神经内分泌的有丝分裂原，其通过与GPR37结合来进行信号传递并促进细胞分裂。
T7459	Abametapir 5 5'-二甲基-2,2-联吡啶,HA-44,BRN 0123183	MMP; Others; Parasite	Microbiology/Virology; Others; Proteases/Proteasome
	Abametapir (BRN 0123183) 是一种金属蛋白酶抑制剂，能够靶向对卵孵化和虱子发育至关重要的金属蛋白酶。
T26889	Borofalan(10B) L-4-Boronophenylalanine,4-10硼酸-L-苯丙氨酸	Others	Others
	Borofalan(10B) (L-4-Boronophenylalanine) 具有抗肿瘤作用，可用于研究复发性或局部晚期头颈癌。
T10337	Antimicrobial Compound 1	Antibacterial	Microbiology/Virology
	Antimicrobial Compound 1 是一种烷基吡啶鎓化合物，尾部为 12C，头部为 4-羧基。 Antimicrobial Compound 1 对枯草芽孢杆菌和大肠杆菌具有抗菌活性。
T17035	Temoporfin 替莫卟吩,替莫泊芬	Others	Others
	Temoporfin 能够用于头颈部鳞状细胞癌的光动力学研究。
T76696	Onvatilimab JNJ-61610588	Others	Others
	Onvatilimab (JNJ-61610588) 是一种人 IgG1κ 抗 VISTA (T 细胞激活的 V 域 Ig 抑制剂) 单克隆抗体。Onvatilimab 具有抗肿瘤活性，可用于治疗晚期头颈癌。。
T5330	Fluralaner AH252723,氟雷拉纳,A1443	GABA Receptor; Parasite	Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience
	Fluralaner (A1443) 是一种异恶唑啉杀外寄生虫剂。它有效且选择性地抑制 GABA 受体通道阻滞剂 EBOB 与家蝇头膜的结合，IC50值为 455 pM。
TP1114L	Leucokinin VIII acetate Leucokinin 8	Others	Others
	Leucokinin VIII acetate (Leucokinin 8) 是一种从蟑螂头部提取物中分离的利尿八肽。
T0790	Carbaryl 1-naphthyl methylcarbamate,甲萘威,Sevin	AChR	Neuroscience
	Carbaryl (1-naphthyl methylcarbamate) 可作为一种杀虫剂。
T25284	DAC-2-25 DAC 225,DAC-225,DAC 2 25	Others	Others
	DAC-2-25是 Hydra 头部再生调节剂。它通过诱导 Hydra 的同源转化而起作用。
T2618	LGK974 LGK 974,LGK-974,NVP-LGK974,WNT974	Porcupine	Stem Cells
	LGK974 (NVP-LGK974) 是一种有效的、特异性的、具有口服活性的Porcupine(PORCN) 抑制剂(IC50:0.1 nM)。
T77423	Lirilumab ONO-4483,IPH2102	Virus Protease	Microbiology/Virology
	Lirilumab (IPH2102) 是一种针对杀伤性免疫球蛋白样受体抗体 KIR2D 的抗体，具有抗肿瘤活性，通过 Vav1 依赖性 NF-κB 去抑制增强自然杀伤细胞的抗 HPV+ 宫颈癌活性，可用于研究白血病、头颈部鳞状细胞癌 (SCCHN)。
T76890	Petosemtamab MCLA 158	EGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	Petosemtamab (MCLA 158) 是一种高效的抗 EGFR (Kd: 0.22 nM) 和抗 LGR5 (Kd: 0.86 nM) 单克隆抗体。Petosemtamab 促使 LGR5+ 癌细胞中的 EGFR 信号传导中断和受体分解。Petosemtamab 可用于头颈部鳞状细胞癌 (HNSCC)、转移性结直肠癌 (CRC) 等实体瘤的研究。
T71912	PD 173955-Analog1	Others	Others
	PD 173955-Analog1 is a potent c-Src inhibitor known to have activity against a variety of cancers including colon, lung, head and neck carcinoma.
T25683	Leucomyosuppressin p-Glu-asp-val-asp-his-val-phe-leu-arg-phe-NH2	Others	Others
	Leucomyosuppressin, isolated from head extracts of the cockroach Leucophaea maderae, inhibits evoked transmitter release at the mealworm neuromuscular junction.
T74742	TRPV1 activator-2	Others	Others
	TRPV1 activator-2 (compound 9)为辣椒素类似物，特异性与脂-水通道残基相互作用。
TP1114	Leucokinin VIII Leucokinin 8
	Leucokinin VIII is an diuretic octapeptide isolated form head extracts of the cockroach.
T20688	Leucokinin I	Others	Others
	Leucokinin I is an eight amino acid neuropeptide. It is found in the nervous system of the bowfly and isolated from the head of Madeira cockroach Leucophaea maderae.
T84550	AMC Arachidonoyl Amide AMC-AA	Others	Others
	Arachidonoyl amide (AMC-AA) is a fatty acid amide among several that serve to quantify fatty acid amide hydrolase (FAAH) activity. FAAH, with its relative lack of selectivity, processes various amide head groups beyond ethanolamine, the head group of its primary endogenous substrate, anandamide (AEA). The interaction of AMC-AA with FAAH leads to the liberation of fluorescent aminomethyl coumarin, which has an absorption peak at 360 nm and emission at 465 nm. This fluorescence release facilitates...
T29965	Amethopterin DL-Amethopterin	Others	Others
	Amethopterin is a chemotherapy drug and immune system inhibitor used to treat cancers of the blood, bone, lung, breast, head, and neck. In addition, it can treat rheumatoid arthritis and psoriasis.
T69857	DB293	Others	Others
	DB293 is an inhibitor of PIT-1 and BRN-3 transcription factors. DB293 binds as head-to-tail stacked dimers in the minor groove of 5'-ATGA sequence, thereby leading to an increase in the size of minor groove.
T82188	HN-1
	HN-1为一种12-mer多肽，在头颈部鳞状细胞癌(HNSCC)细胞上展现特异性活性。作为肿瘤特异性肽，HN-1可渗透肿瘤组织，并在细胞膜上转移活性分子。
T79506	Topoisomerase II inhibitor 15	Topoisomerase	DNA Damage/DNA Repair
	TopoisomeraseII inhibitor 15 (compound 2g) 为 TopoisomeraseII 的一种抑制剂，能有效诱导细胞凋亡 (apoptotic) 并对头颈部肿瘤展示出较高选择性。
T74288	SQDG	Others	Others
	SQDG 是一种膜脂，头部基团含有糖部分，用于研究结构脂在LNP制剂中的作用。
T77266	C13-112-tri-tail	Others	Others
	C13-112-tri-tail 是一种阳离子类脂化合物，可用于配制脂质纳米颗粒。
T21119	Cevimeline AF-102B,西维美林,FKS 508,SNI 2011,HSDB 7286	Others	Others
	Cevimeline, a parasympathomimetic and muscarinic agonist, affects M1 and M3 receptors. Cevimeline has been shown to treat dry mouth and Sj gren's syndrome. It is also used to reduce Xerostomia symptoms and increase salivary flow in head and neck cancer survivors after radiotherapy.
T77269	C13-113-tetra-tail	Others	Others
	C13-113-tetra-tail 是一种阳离子类脂化合物，可用于配制脂质纳米颗粒。
T28494	R-82913 NSC 637653, 9-Cl-Tibo,R 82913,R82913. 9-Cmbib	Others	Others
	R-82913 is a RNA-directed DNA polymerase inhibitor. R 82913 reduce 5-HT2 receptor-mediated DOI-head-shakes in mice. R82913 inhibited the replication of thirteen different strains of HIV-1 in CEM cells with a median IC50 of 0.15 microM. R82913 was 20-fold
T19377	Ioxilan	Others	Others
	Ioxilan is a low-osmolar, nonionic, and tri-iodinated diagnostic contrast agent used for excretory urography and contrast-enhanced computed tomographic (CECT) imaging of the head and body. Intravascularly injected causes opacification of vessels, allowing for radiographic visualization of internal structures until significant hemodilution occurs.
T77267	C13-113-tri-tail	Others	Others
	C13-113-tri tail 是一种阳离子类脂化合物，可用于配制脂质纳米颗粒。
T68297	Dilmapimod tosylate	Others	Others
	Dilmapimod tosylate is a potent p38 mitogen-activated protein kinase (MAPK) inhibitor. It was investigated for its anti-inflammatory effect in non-head injury trauma patients at risk for developing acute respiratory distress syndrome. IL-1β was identified as a gene regulated by dilmapimod that could influence c-reactive protein levels. Dilmapimod had been in phase III clinical trials by GlaxoSmithKline for the treatment of rheumatoid arthritis, neuropathic pain, coronary artery disease (CAD) and...
T83423	1-Palmitoyl-2-[3-(diphenylhexatriene)propanoyl]-sn-phosphatidylcholine
	1-Palmitoyl-2-[3-(diphenylhexatriene)propanoyl]-sn-phosphatidylcholine 是一种荧光探针，其极性磷脂酰乙醇胺头基适用于测定脂蛋白与血浆表面脂质的氧化。
T76918	Barecetamab
	Barecetamab (ISU-104) 是一种人源话抗 ErbB3单克隆抗体。Barecetamab 可用于复发/转移性 (R/M) 头颈部鳞状细胞癌 (HNSCC) 的研究。
T21964	KP372-1	Others	Others
	KP372-1是一种 Akt 的抑制剂，通过阻断 PI3K 通路信号，抑制细胞增殖，同时诱导癌细胞凋亡，可用于头颈部鳞状细胞癌的研究。
T77268	C13-112-tetra-tail	Others	Others
	C13-112-tetra-tail 是一种阳离子类脂化合物，可用于配制脂质纳米颗粒。
T71491	Enadoline (Free Base)	Others	Others
	Enadoline (Free Base) is a kappa-opioid receptor agonist; PD 129290 (CAM 570; CI 977) is the S,S(-)-enantiomer; PD 129289 (CAM 569) is the corresponding R,R(+)-enantiomer. In human studies, it produced visual distortions and feelings of dissociation, reminiscent of the effects of salvinorin A. It was studied as a potential analgesic, but abandoned because of the dose-limiting effects of dysphoria, which could be expected from a κ-opioid agonist. There was mention of its potential in treating com...
T76372	TRAF6 peptide
	TRAF6 peptide 是一种特异性的TRAF6-p62相互作用抑制剂。TRAF6 peptide 能消除 NGF 依赖性TrkA 泛素化。TRAF6 peptide 在诸如阿尔茨海默症 (AD)、帕金森、ALS、头部外伤、癫痫和中风等神经系统性疾病中具有较好的研究潜力。
T62790	JH-XIV-68-3	Others	Others
	JH-XIV-68-3 是一种选择性的 DYRK1A/B 大环抑制剂。JH-XIV-68-3 在生化和细胞测定中能够选择性作用于 DYRK1A 和近亲 DYRK1B。JH-XIV-68-3 在头颈部鳞状细胞癌 (HNSCC) 细胞系中具有抗肿瘤作用。
T37217	N-Decanoyl p-Nitroaniline
	N-Decanoyl p-nitroaniline (DepNA) is one of several nitroaniline fatty acid amides which can be used to measure fatty acid amide hydrolase (FAAH) activity. FAAH is a relatively unselective enzyme in that it accepts a variety of amide head groups other than the ethanolamine of its endogenous substrate anandamide (AEA). It also will hydrolyze fatty acid amides with fewer carbons and fewer double bonds than arachidonate. Exposure of DepNA to FAAH activity results in the release of the yellow colori...
T78221	TRAF6 peptide TFA	E1/E2/E3 Enzyme	Ubiquitination
	TRAF6 peptide TFA是一种抑制TRAF6-p62相互作用的特异性分子，可抑制NGF依赖的TrkA泛素化，展现在阿尔茨海默症（AD）、帕金森病、ALS、创伤性脑损伤、癫痫和中风等神经系统疾病研究中的应用潜力。
T85008	Phosphatidylinositol (plant, wheat germ) sodium	Others	Others
	Phosphatidylinositols, comprising about 10% of total cellular phospholipids, are glycerophospholipids featuring a glycerol backbone, two non-polar fatty acid tails (primarily C16:0 and C18:0), and a polar inositol head group. Synthesized from cytidine diphosphate diacylglycerol (CPD-DAG) and myoinositol via phosphoinositol synthase, these compounds play pivotal roles in cellular processes, including calcium regulation, vesicle trafficking, mitogenesis, cell survival, and actin rearrangement. Pho...
T35907	Paraherquamide A	Others	Others
	Paraherquamide A is a mycotoxin anthelmintic originally isolated from P. paraherquei. It binds to acetylcholine receptors (IC50 = 0.5 nM for head homogenates of M. domestica) and acts as an antagonist. Paraherquamide A is toxic to C. elegans (LD50 = 2.5 μg/ml) and effective against T. colubriformis infection in gerbils when used at doses ranging from 0.39 to 200 mg/kg. It is toxic to mice (LD50 = 14.9 mg/kg).
T68661	Edatrexate CGP 30694	Others	Others
	Edatrexate (CGP 30694)，即 10-乙基-10-去甲氨基蝶呤，是甲氨蝶呤Methotrexate 的类似物，对耐 MTX 肿瘤具有抗肿瘤活性。Edatrexate 是一种抗叶酸抗代谢物，可用于研究非小细胞肺癌，乳腺癌，非霍奇金淋巴瘤和头颈部癌症的研究。
T36368	2H-Cho-Arg (trifluoroacetate salt)	Others	Others
	2H-Cho-Arg is a steroid-based cationic lipid that contains a 2H-cholesterol skeleton coupled to an L-arginine head group and can be used to facilitate gene transfection. It forms a complex with plasmid DNA (pDNA) and decreases pDNA migration in an electrophoretic mobility shift assay at +/- charge ratios of 4 or higher. 2H-Cho-Arg facilitates transfection of a luciferase gene into H1299 cells, an effect that is reversed by the lipid raft-mediated endocytosis inhibitor methyl-β-cyclodextrin and t...
T36350	Cho-Arg (trifluoroacetate salt)	Others	Others
	Cho-Arg is a steroid-based cationic lipid that contains a cholesterol skeleton coupled to an L-arginine head group. It forms a complex with plasmid DNA and decreases plasmid DNA migration in an agarose-gel retardant assay at charge ratios greater than or equal to 4. Cho-Arg facilitates transfection of plasmid DNA into H1299 and HeLa cells in the presence or absence of fetal bovine serum, an effect that is reversed by the lipid raft-mediated endocytosis inhibitor methyl-β-cyclodextrin and the cav...
T74564	Phospholipid-PEG-Biotin (MW 2000)	Others	Others
	Phospholipid-PEG-Biotin (MW 2000) 是一种PROTAClinker，属于 PEG 类。可用于合成PROTAC 分子。Phospholipid 是一类含有亲水“头”和疏水“尾”的脂类；PEG 是一种低毒性的亲水水溶性聚合物；生物素是一种酶辅因子，可用于标记蛋白质。
T74566	Phospholipid-PEG-Biotin (MW 5000)	Others	Others
	Phospholipid-PEG-Biotin (MW 5000)为含有磷脂的PEG衍生物，适用于脂质体和细胞表面的修饰，及胰岛细胞移植。Phospholipid具亲水性“头部”与疏水性“尾部”结构，PEG为亲水性低毒聚合物，生物素则作为酶辅因子，用于蛋白质标记。
T35810	C24 dihydro Ceramide (d18:0/24:0) Cer(d18:0/24:0)	Others	Others
	C24 dihydro Ceramide is a sphingolipid that has been found in the stratum corneum of human skin.[1] It is found in higher concentrations in female sebum compared to male sebum.[2] C24 dihydro Ceramide levels positively correlate with cytotoxicity in CCRF-CEM, MOLT-4, COG-LL-317h, and COG-LL-332h T cell acute lymphoblastic leukemia (ALL) cell lines.[4] Levels of C24 dihydro ceramide are increased by 149.49-fold in dihydroceramide desaturase 1 (DEGS1) knockdown UM-SCC-22A human head and neck squam...
T72776	NR2F1 agonist 1	Others	Others
	NR2F1 agonist 1 是一种核受体 NR2F1激动剂，可特异性激活恶性细胞的休眠程序。NR2F1 agonist 1 上调 NR2F1 和调节休眠的下游靶基因。NR2F1 agonist 1 通过 NR2F1 激活在头颈部鳞状细胞癌 (HNSCC) 中诱导神经嵴样生长抑制。NR2F1 agonist 1 在小鼠原发肿瘤模型中抑制肿瘤生长。
T63556	EGFR-IN-59	Others	Others
	EGFR-IN-59 是 EGFR 抑制剂，其IC50值为190 nM，也是一直凋亡 (apoptosis) 诱导剂。EGFR-IN-59 对非小肺癌细胞系 (A549) 和正常肺成纤维细胞 (WI38) 表现出细胞毒性的IC50分别为 8.62 和 52.6 μM。EGFR-IN-59 能够用于研究非小细胞肺癌 (NSCLC)、头颈癌、乳腺癌和结直肠癌等多种癌症。

化合物

Head activator neuropeptide

Cat.No: T82221

Cat.No: T7459

Synonym: 5 5'-二甲基-2,2-联吡啶,HA-44,BRN 0123183

Target: MMP, Others, Parasite

Cat.No: T26889

Synonym: L-4-Boronophenylalanine,4-10硼酸-L-苯丙氨酸

Target: Others

Antimicrobial Compound 1

Cat.No: T10337

Target: Antibacterial

Cat.No: T17035

Synonym: 替莫卟吩,替莫泊芬

Target: Others

Cat.No: T76696

Synonym: JNJ-61610588

Target: Others

Cat.No: T5330

Synonym: AH252723,氟雷拉纳,A1443

Target: GABA Receptor, Parasite

Leucokinin VIII acetate

Cat.No: TP1114L

Synonym: Leucokinin 8

Target: Others

Cat.No: T0790

Synonym: 1-naphthyl methylcarbamate,甲萘威,Sevin

Target: AChR

Cat.No: T25284

Synonym: DAC 225,DAC-225,DAC 2 25

Target: Others

Cat.No: T2618

Synonym: LGK 974,LGK-974,NVP-LGK974,WNT974

Target: Porcupine

Cat.No: T77423

Synonym: ONO-4483,IPH2102

Target: Virus Protease

Cat.No: T76890

Synonym: MCLA 158

Target: EGFR

PD 173955-Analog1

Cat.No: T71912

Target: Others

Leucomyosuppressin

Cat.No: T25683

Synonym: p-Glu-asp-val-asp-his-val-phe-leu-arg-phe-NH2

Target: Others

TRPV1 activator-2

Cat.No: T74742

Target: Others

Leucokinin VIII

Cat.No: TP1114

Synonym: Leucokinin 8

Cat.No: T20688

Target: Others

AMC Arachidonoyl Amide

Cat.No: T84550

Synonym: AMC-AA

Target: Others

Cat.No: T29965

Synonym: DL-Amethopterin

Target: Others

Cat.No: T69857

Target: Others

Cat.No: T82188

Topoisomerase II inhibitor 15

Cat.No: T79506

Target: Topoisomerase

Cat.No: T74288

Target: Others

C13-112-tri-tail

Cat.No: T77266

Target: Others

Cat.No: T21119

Synonym: AF-102B,西维美林,FKS 508,SNI 2011,HSDB 7286

Target: Others

C13-113-tetra-tail

Cat.No: T77269

Target: Others

Cat.No: T28494

Synonym: NSC 637653, 9-Cl-Tibo,R 82913,R82913. 9-Cmbib

Target: Others

Cat.No: T19377

Target: Others

C13-113-tri-tail

Cat.No: T77267

Target: Others

Dilmapimod tosylate

Cat.No: T68297

Target: Others

1-Palmitoyl-2-[3-(diphenylhexatriene)propanoyl]-sn-phosphatidylcholine

Cat.No: T83423

Cat.No: T76918

Cat.No: T21964

Target: Others

C13-112-tetra-tail

Cat.No: T77268

Target: Others

Enadoline (Free Base)

Cat.No: T71491

Target: Others

Cat.No: T76372

Cat.No: T62790

Target: Others

N-Decanoyl p-Nitroaniline

Cat.No: T37217

TRAF6 peptide TFA

Cat.No: T78221

Target: E1/E2/E3 Enzyme

Phosphatidylinositol (plant, wheat germ) sodium

Cat.No: T85008

Target: Others

Paraherquamide A

Cat.No: T35907

Target: Others

Cat.No: T68661

Synonym: CGP 30694

Target: Others

2H-Cho-Arg (trifluoroacetate salt)

Cat.No: T36368

Target: Others

Cho-Arg (trifluoroacetate salt)

Cat.No: T36350

Target: Others

Phospholipid-PEG-Biotin (MW 2000)

Cat.No: T74564

Target: Others

Phospholipid-PEG-Biotin (MW 5000)

Cat.No: T74566

Target: Others

C24 dihydro Ceramide (d18:0/24:0)

Cat.No: T35810

Synonym: Cer(d18:0/24:0)

Target: Others

NR2F1 agonist 1

Cat.No: T72776

Target: Others

Cat.No: T63556

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T7727	Se-Methylselenocysteine Se MSC,SeMCys,MSeC,L-硒甲基硒代半胱氨酸,Se-MSC,SeMSC	BCL; IAP; Caspase	Apoptosis; Proteases/Proteasome
	Se-Methylselenocysteine (Se-MSC) 是具有口服活性的甲基硒前体，具有强大的抗氧化活性和抗癌活性。Se-Methylselenocysteine 可诱导细胞凋亡。
TN2539	1beta-Hydroxyalantolactone	IL Receptor; TNF	Apoptosis; Immunology/Inflammation
	1beta-Hydroxyalantolactone 是从药用植物大英花的花头中分离出的小分子化合物，可抑制细胞中TNF-α、IL-17、IFN-γ的表达，促进TNF-α、IFN-γ、IL-17的分泌，可防治类风湿性关节炎。
T3674	Hydroxysafflor yellow A 藏红花,羟基红花黄色素A,HSYA,Safflomin A	TGF-beta/Smad	Stem Cells
	Hydroxysafflor yellow A (Safflomin A) 是一种黄酮类天然产物，从中药红花中分离得到，具有抗癌作用。
T0729	Benzyl benzoate Ascabiol,Novoscabin,Scabitox,苯甲酸苄酯,Benzoic acid benzyl ester	Parasite	Microbiology/Virology
	Benzyl benzoate (Benzoic acid benzyl ester) 是化妆品中的香料成分，可研究疥疮和蠕形螨相关的炎症性皮肤病。
T4889	2,6-Diaminoheptanedioic acid	Others; Endogenous Metabolite	Metabolism; Others
	2,6-Diaminoheptanedioic acid 是内源性代谢产物的一种。
T3229	Cytochalasin D	ATPase; p38 MAPK; Calcium Channel; Akt; PI3K	Cytoskeletal Signaling; MAPK; Membrane transporter/Ion channel; Metabolism; PI3K/Akt/mTOR signaling
	Cytochalasin D is an actin inhibitor, the removal of actin stress fibers is crucial for the chondrogenic differentiation. It may be an inhibitor of some fertilization processes such as sperm penetration or sperm head decondensation. Cytochalasin D inhibit
TN7240	Erinacine A	ROS	Immunology/Inflammation
	Erinacine A 是一种可从猴头菇中提取出的抗癌化合物，能够通过活性氧类 (ROS) 的产生促使癌细胞死亡。Erinacine A 可能通过参与信号通路的调节从而发挥其抗癌活性。Erinacine A 具有抗癌、抗肿瘤和神经保护活性。

天然产物

Se-Methylselenocysteine

Cat.No: T7727

Synonym: Se MSC,SeMCys,MSeC,L-硒甲基硒代半胱氨酸,Se-MSC,SeMSC

Target: BCL, IAP, Caspase

1beta-Hydroxyalantolactone

Cat.No: TN2539

Target: IL Receptor, TNF

Hydroxysafflor yellow A

Cat.No: T3674

Synonym: 藏红花,羟基红花黄色素A,HSYA,Safflomin A

Target: TGF-beta/Smad

Benzyl benzoate

Cat.No: T0729

Synonym: Ascabiol,Novoscabin,Scabitox,苯甲酸苄酯,Benzoic acid benzyl ester

Target: Parasite

2,6-Diaminoheptanedioic acid

Cat.No: T4889

Target: Others, Endogenous Metabolite

Cat.No: T3229

Target: ATPase, p38 MAPK, Calcium Channel, Akt, PI3K

Cat.No: TN7240

Target: ROS

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-00411	Influenza A H5N1 (A/bar-headed goose/Qinghai/1A/2005) Hemagglutinin/HA Protein (His) Harvey rat sarcoma viral oncogene homolog	H5N1	Baculovirus Insect Cells
	Influenza A H5N1 (A/bar-headed goose/Qinghai/1A/2005) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59.6 kDa and the accession number is Q195D4.
TMPY-01623	Influenza A H13N8 (A/black-headed gull/Netherlands/1/00) Hemagglutinin/HA1 Protein (His) Harvey rat sarcoma viral oncogene homolog	H13N8	HEK293 Cells
	Influenza A H13N8 (A/black-headed gull/Netherlands/1/00) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.4 kDa and the accession number is Q5DL26.
TMPY-01124	Influenza A H5N1 (A/bar-headed goose/Qinghai/14/2008) Hemagglutinin/HA Protein (His) Harvey rat sarcoma viral oncogene homolog	H5N1	HEK293 Cells
	Influenza A H5N1 (A/bar-headed goose/Qinghai/14/2008) Hemagglutinin/HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.5 kDa and the accession number is B8YQI3.
TMPY-00267	Influenza A H13N6 (A/black-headed gull/Sweden/1/1999) Hemagglutinin/HA Protein (His) Harvey rat sarcoma viral oncogene homolog	H13N6	Baculovirus Insect Cells
	Influenza A H13N6 (A/black-headed gull/Sweden/1/1999) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 37.3 kDa and the accession number is Q5DL25.
TMPY-03229	Influenza A H5N1 (A/bar-headed goose/Qinghai/1A/2005) Hemagglutinin/HA1 Protein (His) Harvey rat sarcoma viral oncogene homolog	H5N1	HEK293 Cells
	Influenza A H5N1 (A/bar-headed goose/Qinghai/1A/2005) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.3 kDa and the accession number is Q195D4.
TMPY-01533	Influenza A H16N3 (A/black-headed gull/Sweden/5/99) Hemagglutinin/HA1 Protein (His) Harvey rat sarcoma viral oncogene homolog	H16N3	HEK293 Cells
	Influenza A H16N3 (A/black-headed gull/Sweden/5/99) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.5 kDa and the accession number is Q5DL21.
TMPY-00079	Influenza A H13N8 (A/black-headed gull/Netherlands/1/00) Hemagglutinin/HA Protein (His) Harvey rat sarcoma viral oncogene homolog	H13N8	Baculovirus Insect Cells
	Influenza A H13N8 (A/black-headed gull/Netherlands/1/00) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 58.5 kDa and the accession number is Q5DL26.
TMPY-01532	Influenza A H16N3 (A/black-headed gull/Sweden/5/99) Hemagglutinin/HA Protein (His) Harvey rat sarcoma viral oncogene homolog	H16N3	HEK293 Cells
	Influenza A H16N3 (A/black-headed gull/Sweden/5/99) Hemagglutinin/HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 58.6 kDa and the accession number is Q5DL21.
TMPY-00106	Influenza A H12N3 (A/bar headed goose/Mongolia/143/2005) Hemagglutinin/HA1 Protein (His) Harvey rat sarcoma viral oncogene homolog	H12N3	HEK293 Cells
	Influenza A H12N3 (A/bar headed goose/Mongolia/143/2005) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.4 kDa and the accession number is D2JIV2.
TMPY-04862	Influenza A H13N6 (A/black-headed gull/Sweden/1/1999) Hemagglutinin/HA1 Protein (His) Harvey rat sarcoma viral oncogene homolog	H13N6	HEK293 Cells
	Influenza A H13N6 (A/black-headed gull/Sweden/1/1999) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.3 kDa and the accession number is Q5DL25.
TMPY-03272	COL4A3 Protein, Rat, Recombinant (hFc) collagen, type IV, α3 (Goodpasture antigen),collagen, type I...	Rat	HEK293 Cells
	COL4A3 is a major structural component of basement membranes. It is composed of 3 alpha subunits, which are encoded by 6 different genes, alpha 1 through alpha 6. Each of these alpha subunits can form a triple helix structure with 2 other subunits to form COL4A3. Autoantibodies bind to the collagen molecules in the basement membranes of alveoli and glomeruli can cause goodpasture syndrome. COL4A3 is also linked to an autosomal recessive form of alport syndrome. COL4A3 is organized in a he...
TMPH-00854	RPS18 Protein, Human, Recombinant (GST) Small ribosomal subunit protein uS13,Ke-3,40S ribosomal prot...	Human	E. coli
	Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA. RPS18 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 44.6 kDa and the accession number is P62269.
TMPH-03517	Ribosomal protein uS5 Protein, S. aureus, Recombinant (His & Myc) 30S ribosomal protein S5,rpsE,Small ribosomal subunit protei...	Staphylococcus aureus	E. coli
	With S4 and S12 plays an important role in translational accuracy.; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Ribosomal protein uS5 Protein, S. aureus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 24.8 kDa and the accession number is A6QJ75.
TMPH-00754	Capsid decoration Protein, Escherichia phage lambda, Recombinant (GST) Gene product D,Auxiliary protein D,Major capsid protein D,gp...	Escherichia phage lambda	E. coli
	Stabilizes the expansion of the capsid head shell after genome packaging. The packaging of viral genome in the procapsid triggers a dramatic reconfiguration of the capsid shell, expanding from roughly 50nm to 60nm while the capsid thickness decreases. 415 capsid decoration protein molecules cooperatively bind the expanded capsid, thereby stabilizing the mature capsid shell. Capsid decoration Protein, Escherichia phage lambda, Recombinant (GST) is expressed in E. coli expression system with N-GST...
TMPK-00871	DSG3 Protein, Human, Recombinant (His) CDHF6,SG3,DSG-3,DSG3,Desmoglein-3,PVA	Human	HEK293 Cells
	To identify genes that could potentially serve as molecular therapeutic markers for human head and neck cancer (HNC),DSG3 is identified overexpressed in HNC, with the degree of overexpression associated with clinicopathologic features of the tumor. Inhibition of DSG3 significantly suppresses carcinogenic potential in cellular and in vivo animal studies. DSG3 is a potential molecular target in the development of adjuvant therapy for HNC. DSG3 Protein, Human, Recombinant (His) is expressed in HEK2...
TMPH-03390	TRPV2 Protein, Rat, Recombinant (His) Transient receptor potential cation channel subfamily V memb...	Rat	E. coli
	Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by growth factors, like IGF1, PDGF and morphogenetic neuropeptide/head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius; is not activated by vanilloids and acidic pH. TRPV2 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 88.2 kDa and th...
TMPH-00562	30S ribosomal protein S7 Protein, E. coli, Recombinant (His) 30S ribosomal protein S7,rpsG,Small ribosomal subunit protei...	E. coli	E. coli
	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, where it has been shown to contact mRNA. Has been shown to contact tRNA in both the P and E sites; it probably blocks exit of the E site tRNA.; Protein S7 is also a translational repressor protein; it regulates the expression of the str operon members to different degrees by binding to its mRNA...
TMPK-00726	DSG3 Protein, Mouse, Recombinant (His) SG3,PVA,DSG3,CDHF6,Desmoglein-3,DSG-3	Mouse	HEK293 Cells
	To identify genes that could potentially serve as molecular therapeutic markers for human head and neck cancer (HNC),DSG3 is identified overexpressed in HNC, with the degree of overexpression associated with clinicopathologic features of the tumor. Inhibition of DSG3 significantly suppresses carcinogenic potential in cellular and in vivo animal studies. DSG3 is a potential molecular target in the development of adjuvant therapy for HNC. DSG3 Protein, Mouse, Recombinant (His) is expressed in HEK2...
TMPK-01485	HLA-A*01:01&B2M&DSG3 (YTDNWLAVY) Monomer Protein, Human, MHC (His & Avi) CDHF6,DG3,DSG3,PVA,DSG-3,Desmoglein-3	Human	HEK293 Cells
	DSG3 is overexpressed in head neck cancer and is a potential molecular target for inhibition of oncogenesis. DSG3 is identified overexpressed in HNC, with the degree of overexpression associated with clinicopathologic features of the tumor. Inhibition of DSG3 significantly suppresses carcinogenic potential in cellular and in vivo animal studies. These findings suggest that DSG3 is a potential molecular target in the development of adjuvant therapy for HNC.
TMPJ-00806	HMBS Protein, Human, Recombinant (His) Pre-Uroporphyrinogen Synthase,PBG-D,Hydroxymethylbilane Synt...	Human	HEK293 Cells
	Porphobilinogen Deaminase (HMBS) is a member of the HMBS family. PBGD is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. HMBS is involved in the production of heme, which is important for all of the body's organs, although it is most abundant in the blood, bone marrow, and liver. In addition, Heme is an essential component of iron-containing proteins called hemoproteins, including...
TMPH-01640	MRGPRX2 Protein, Human, Recombinant (His) Mas-related G-protein coupled receptor member X2,MRGPRX2	Human	E. coli
	Mast cell-specific receptor for basic secretagogues, i.e. cationic amphiphilic drugs, as well as endo- or exogenous peptides, consisting of a basic head group and a hydrophobic core. Recognizes and binds small molecules containing a cyclized tetrahydroisoquinoline (THIQ), such as non-steroidal neuromuscular blocking drugs (NMBDs), including tubocurarine and atracurium. In response to these compounds, mediates pseudo-allergic reactions characterized by histamine release, inflammation and airway c...
TMPU-00004	STAT5A Protein, Human, Recombinant (His) MGF,Signal transducer and activator of transcription 5A	Human	E. coli
	Signal transducer and activator of transcription 5A is a protein that in humans is encoded by the STAT5A gene. Many studies have indicated a key role of STAT5a in leukemia, breast, colon, head and neck, and prostate cancer. Until recently, the unique characteristics and function of STAT5a in these cancers have not been delineated from STAT5b, and more research into their differential behavior is warranted. Because of its integral role in immune cell development, STAT5a may contribute to tumor de...
TMPH-02162	Synaptotagmin-1 Protein, Human, Recombinant (His) SYT1,Synaptotagmin-1,p65,Synaptotagmin I	Human	E. coli
	Calcium sensor that participates in triggering neurotransmitter release at the synapse. May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at leas...
TMPJ-00716	Cerberus 1/CER1 Protein, Human, Recombinant (HEK293, His) DAN Domain Family Member 4,Cerberus,Cerberus-Related Protein...	Human	HEK293 Cells
	Cerberus 1 is a secreted glycoprotein that forms disulfide-linked homodimers. It is a cytokine member of the DAN domain family of BMP antagonists that includes DAN (DAND1), Gremlin/Drm (DAND2), PRDC (Protein Related to Dan and Cerberus, DAND3), and COCO/Dante (DAND5). DAN family members contain a cysteine knot domain that is homologous to that found in other TGF-beta superfamily ligands. At the onset of gastrulation, Cerberus 1 is transiently expressed in anterior endodermal structures in respon...
TMPJ-00554	Vinculin Protein, Human, Recombinant Metavinculin,VCL,Vinculin	Human	E. coli
	Vinculin is a focal adhesion and cytoskeletal protein that distributed mainly at cell-cell junctions and cell-extracellular matrix (ECM) adhesion that belongs to the Vinculin/α-Catenin family. Vinculin is an Actin-binding protein and component of the Actin-Linking Functional module that senses and feels the mechanical properties of the extracellular environment. Vinculin is also a key factor that couples, transmits, transduces, and regulates mechanical force between the cytoskeleton and adhesion...
TMPY-02803	IDO2 Protein, Human, Recombinant (His) indoleamine 2,3-dioxygenase 2,INDOL1	Human	E. coli
	IDO2 belongs to the indoleamine 2,3-dioxygenase family. Indoleamine 2,3-dioxgyenase (IDO), is a cytosolic haem protein which, together with the hepatic enzyme tryptophan 2,3-dioxygenase, catalyzes the conversion of tryptophan and other indole derivatives to kynurenines. In addition to classic IDO (IDO1), a new variant, IDO2, has recently been described. IDO2 is expressed in the liver, small intestine, spleen, placenta, thymus, lung, brain, kidney, and colon. IDO is widely distributed in human ti...
TMPH-03426	Rotavirus X (isolate novel adult diarrhea rotavirus-B219) VP4 Protein (His) Hemagglutinin,Outer capsid protein VP4	RVX	P. pastoris (Yeast)
	Spike-forming protein that mediates virion attachment to the host epithelial cell receptors and plays a major role in cell penetration, determination of host range restriction and virulence. Rotavirus attachment and entry into the host cell probably involves multiple sequential contacts between the outer capsid proteins VP4 and VP7, and the cell receptors. It is subsequently lost, together with VP7, following virus entry into the host cell. Following entry into the host cell, low intracellular o...
TMPY-06585	C1s Protein, Human, Recombinant (His) complement component 1, s subcomponent,C1s,FLJ44757	Human	HEK293 Cells
	Complement is an integral component of the adaptive and innate immune systems and represents one of the major effector systems for the immune responses. The classical complement pathway is triggered by C1, a complex composed of the binding protein C1q and two proenzymes, C1r and C1s. Upon binding of IgG to the head of C1q, C1r undergoes autoactivation and in turn cleaves and activates C1s. C1r and C1s, the proteases responsible for activation and proteolytic activity of the C1 complex of complem...
TMPH-03753	MYLK Protein, Human, Recombinant (His) MYLK,Myosin light chain kinase, smooth muscle,Telokin,Kinase...	Human	E. coli
	Calcium/calmodulin-dependent myosin light chain kinase implicated in smooth muscle contraction via phosphorylation of myosin light chains (MLC). Also regulates actin-myosin interaction through a non-kinase activity. Phosphorylates PTK2B/PYK2 and myosin light-chains. Involved in the inflammatory response (e.g. apoptosis, vascular permeability, leukocyte diapedesis), cell motility and morphology, airway hyperreactivity and other activities relevant to asthma. Required for tonic airway smooth muscl...

重组蛋白

Influenza A H5N1 (A/bar-headed goose/Qinghai/1A/2005) Hemagglutinin/HA Protein (His)

Cat.No: TMPY-00411

Species: H5N1

Expression System: Baculovirus Insect Cells

Influenza A H13N8 (A/black-headed gull/Netherlands/1/00) Hemagglutinin/HA1 Protein (His)

Cat.No: TMPY-01623

Species: H13N8

Expression System: HEK293 Cells

Influenza A H5N1 (A/bar-headed goose/Qinghai/14/2008) Hemagglutinin/HA Protein (His)

Cat.No: TMPY-01124

Species: H5N1

Expression System: HEK293 Cells

Influenza A H13N6 (A/black-headed gull/Sweden/1/1999) Hemagglutinin/HA Protein (His)

Cat.No: TMPY-00267

Species: H13N6

Expression System: Baculovirus Insect Cells

Influenza A H5N1 (A/bar-headed goose/Qinghai/1A/2005) Hemagglutinin/HA1 Protein (His)

Cat.No: TMPY-03229

Species: H5N1

Expression System: HEK293 Cells

Influenza A H16N3 (A/black-headed gull/Sweden/5/99) Hemagglutinin/HA1 Protein (His)

Cat.No: TMPY-01533

Species: H16N3

Expression System: HEK293 Cells

Influenza A H13N8 (A/black-headed gull/Netherlands/1/00) Hemagglutinin/HA Protein (His)

Cat.No: TMPY-00079

Species: H13N8

Expression System: Baculovirus Insect Cells

Influenza A H16N3 (A/black-headed gull/Sweden/5/99) Hemagglutinin/HA Protein (His)

Cat.No: TMPY-01532

Species: H16N3

Expression System: HEK293 Cells

Influenza A H12N3 (A/bar headed goose/Mongolia/143/2005) Hemagglutinin/HA1 Protein (His)

Cat.No: TMPY-00106

Species: H12N3

Expression System: HEK293 Cells

Influenza A H13N6 (A/black-headed gull/Sweden/1/1999) Hemagglutinin/HA1 Protein (His)

Cat.No: TMPY-04862

Species: H13N6

Expression System: HEK293 Cells

COL4A3 Protein, Rat, Recombinant (hFc)

Cat.No: TMPY-03272

Species: Rat

Expression System: HEK293 Cells

RPS18 Protein, Human, Recombinant (GST)

Cat.No: TMPH-00854

Species: Human

Expression System: E. coli

Ribosomal protein uS5 Protein, S. aureus, Recombinant (His & Myc)

Cat.No: TMPH-03517

Species: Staphylococcus aureus

Expression System: E. coli

Capsid decoration Protein, Escherichia phage lambda, Recombinant (GST)

Cat.No: TMPH-00754

Species: Escherichia phage lambda

Expression System: E. coli

DSG3 Protein, Human, Recombinant (His)

Cat.No: TMPK-00871

Species: Human

Expression System: HEK293 Cells

TRPV2 Protein, Rat, Recombinant (His)

Cat.No: TMPH-03390

Species: Rat

Expression System: E. coli

30S ribosomal protein S7 Protein, E. coli, Recombinant (His)

Cat.No: TMPH-00562

Species: E. coli

Expression System: E. coli

DSG3 Protein, Mouse, Recombinant (His)

Cat.No: TMPK-00726

Species: Mouse

Expression System: HEK293 Cells

HLA-A*01:01&B2M&DSG3 (YTDNWLAVY) Monomer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01485

Species: Human

Expression System: HEK293 Cells

HMBS Protein, Human, Recombinant (His)

Cat.No: TMPJ-00806

Species: Human

Expression System: HEK293 Cells

MRGPRX2 Protein, Human, Recombinant (His)

Cat.No: TMPH-01640

Species: Human

Expression System: E. coli

STAT5A Protein, Human, Recombinant (His)

Cat.No: TMPU-00004

Species: Human

Expression System: E. coli

Synaptotagmin-1 Protein, Human, Recombinant (His)

Cat.No: TMPH-02162

Species: Human

Expression System: E. coli

Cerberus 1/CER1 Protein, Human, Recombinant (HEK293, His)

Cat.No: TMPJ-00716

Species: Human

Expression System: HEK293 Cells

Vinculin Protein, Human, Recombinant

Cat.No: TMPJ-00554

Species: Human

Expression System: E. coli

IDO2 Protein, Human, Recombinant (His)

Cat.No: TMPY-02803

Species: Human

Expression System: E. coli

Rotavirus X (isolate novel adult diarrhea rotavirus-B219) VP4 Protein (His)

Cat.No: TMPH-03426

Species: RVX

Expression System: P. pastoris (Yeast)

C1s Protein, Human, Recombinant (His)

Cat.No: TMPY-06585

Species: Human

Expression System: HEK293 Cells

MYLK Protein, Human, Recombinant (His)

Cat.No: TMPH-03753

Species: Human

Expression System: E. coli

Cat. No.	Product Name	Target	Signaling Pathways
TMIJ-0516	Carbaryl-d3
	Carbaryl-d3 是 Carbaryl 的氘代化合物。Carbaryl 的 CAS 号为 63-25-2。Carbaryl 可作为一种杀虫剂。
T71211	Rizatriptan-d6 benzoate salt
	Rizatriptan-d6 is intended for use as an internal standard for the quantification of rizatriptan by GC- or LC-MS. Rizatriptan is an agonist of the serotonin receptor subtypes 5-HT1B and 5-HT1D. It is selective for 5-HT1B and 5-HT1D receptors over 5-HT1A receptors. Rizatriptan induces vasoconstriction in isolated human middle meningeal arteries. In vivo, rizatriptan reduces head grooming, the number of oculotemporal strokes, eye blinking, and one-eye closures in a Cacna1a mutant transgenic mou...

同位素标记化合物

Cat.No: TMIJ-0516

Rizatriptan-d6 benzoate salt

Cat.No: T71211

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