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Search Results for " composition "

Targets Recommended: PROTAC Linker

45

抑制剂 & 化合物

10

天然产物

2

化合物库

19

重组蛋白

3

同位素标记化合物

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Cat. No.	Product Name
L7000	活性脂质化合物库		385 compounds
	385 种生物活性小分子化合物，用于高通量、高内涵筛选；
L2540	肠道微生物代谢化合物库		614 compounds
	614 种肠道微生物代谢物的集合，可以用于高通量和高内涵筛选；

化合物库

活性脂质化合物库

Cat.No: L7000

Compounds: 385

肠道微生物代谢化合物库

Cat.No: L2540

Compounds: 614

Cat. No.	Product Name	Target	Signaling Pathways
T18788	tert-Butyl 11-aminoundecanoate	PROTAC Linker	PROTAC
	tert-Butyl 11-aminoundecanoate 是一种属于 PEG 类的 PROTAC linker。它可用于合成一系列 PROTAC 分子。
T9614	MERS-CoV-IN-1	SARS-CoV	Microbiology/Virology
	MERS-CoV-IN-1 对冠状病毒的活性具有优异的抑制作用，可用作预防冠状病毒引起疾病的药物组合物。
T0731	Diethyltoluamide N,N-Diethyl-m-toluamide,避蚊胺,DEET,N,N-Diethyl-meta-toluamide,Delphene,避蚊胺（DEET）	AChE; Parasite	Microbiology/Virology; Neuroscience
	Diethyltoluamide (DEET) 是驱虫剂中常见的活性成分，可保护皮肤，防止蚊虫叮咬。
T12710	Retagliptin Phosphate SP 2086,瑞格列汀磷酸盐	Proteasome; DPP-4	Proteases/Proteasome; Ubiquitination
	Retagliptin Phosphate (SP 2086) 是一种选择性、竞争性、口服活性的二肽基肽酶 4 (DPP-4) 抑制剂。Retagliptin phosphate 能够用于 2 型糖尿病 (T2DM) 的研究。
T18363	Monoethyl pimelate	Others; PROTAC Linker	Others; PROTAC
	Monoethyl pimelate 是一种属于 alkyl/ether 类的 PROTAC linker 可用于特异性的 BCL-XLPROTAC 降解剂 (S,R,S)-AHPC-Me-C7 ester 的合成。
T17694	Br-C10-methyl ester 11-溴代十一烷酸甲酯	Others; PROTAC Linker	Others; PROTAC
	Br-C10-methyl ester 是一种属于 alkyl/ether 类的 PROTAC linker，可用于一系列 PROTAC 分子的合成。PROTAC 分子含有两个通过 linker 连接的不同配体，一种是 VHL 配体部分，另一种是靶蛋白配体。
T35353	Elubiol dichlorophenyl imidazoldioxolan,新康唑	Antibacterial	Microbiology/Virology
	Elubiol (dichlorophenyl imidazoldioxolan) 是咪唑类的新型广谱抗真菌产品，可抑制真菌麦角甾醇的生物合成，改变细胞膜中其他脂质化合物的组成。 Elubiol 用于油性皮肤或头皮屑患者的皮肤和头发护理。
T1438	Butoconazole nitrate RS 35887,硝酸布康唑	Estrogen/progestogen Receptor; Antifungal	Endocrinology/Hormones; Microbiology/Virology
	Butoconazole nitrate (RS 35887) 是一种咪唑类抗真菌药物，可治疗由白色念珠菌引起的阴道感染。它可通过抑制类固醇合成起到抗菌作用。
T27015	Cicrotoic acid	Others	Others
	Cicrotoic acid, a biochemical drug, acts on bile flow and liquid composition of human bile.
T38532	7-Deaza-7-propargylamino-ddATP	Others	Others
	7-Deaza-7-propargylamino-ddATP, an analog of ddATP, serves as a viable option for gene sequencing purposes due to its chemical composition.
T33918	Pentanochlor Hortox,Niagara 4512,Solane,Dutom,FMC 4512	Others	Others
	Pentanochlor can be used in agricultural use and biological study of herbicide composition containing a pyrazolyl pyrazole derivative. The impairment of mobility and development in freshwater snails (Physa fontinalis and Lymnaea stagnalis) caused by herbi
T21189	2-Methyldecanenitrile 2-Cyanodecane	Others	Others
	2-Methyldecanenitrile, a component in a perfume composition, has an intense peach character with lactonic undertones. It is stable across the whole pH range, allowing the creation of a stable fruity effect at low concentration in any applications, includi
T21096	Decamethylene glycol alpha,omega-Decanediol,Decamethylenediol,1,10-Dihydroxydecane,Decane-1,10-diol	Others	Others
	Decamethylene glycol is a substance used as a reagent in the biological study of modified oligonucleotide with in vivo antitumoral activity. Also used in the pharmaceutical study on the composition of essential oils obtained from myrrh and frankincense an
T85050	2-Myristyldistearin TG(18:0/14:0/18:0),1,2-Stearin-2-Myristin	Others	Others
	2-Myristyldistearin (SMS)为含有肉豆蔻酸及硬脂酸的三酰基甘油。
T85288	8(Z)-Eicosenoic Acid cis-8-Eicosenoic Acid	Others	Others
	8(Z)-Eicosenoic acid, a cis-unsaturated free fatty acid featuring a 20-carbon chain, enhances acetylcholine (ACh) receptor channel currents without causing depression and augments PCKε phosphorylation of a substrate peptide in Xenopus oocytes. This acid comprises 6% of the fatty acid composition in seed oil extracted from B. collina.
TP1608	PTD-p65-P1 Peptide
	PTD-p65-P1 Peptide, a selective inhibitor of the nuclear transcription factor NF-kappaB, consists of a conjugation between a membrane-translocating peptide derived from antennapedia (PTD) and p65-P1. This composition effectively inhibits activation triggered by diverse inflammatory stimuli.
T38743	Scrambled TRAP Fragment
	Scrambled TRAP Fragment is a variant of the TRAP Fragment compound, characterized by its random amino acid sequence. It is typically employed as a negative control due to its similarity in composition to the active fragment.
T18653	S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate s-1-hydroxy-2-methylpropan-2-yl-methanesulfonothioate	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate, an ADC linker, is a glutathione cleavable compound used for the attachment of monoclonal antibodies (mAb) in antibody-drug conjugates (ADCs). It specifically refers to the Alkyl-Chain composition of the linker portion of these molecules [1].
TP1347	Syntide 2 (TFA) (108334-68-5 free base) Syntide 2 (TFA)
	Syntide 2 (TFA) is a Ca2+ and CaM dependent protein kinase II (CaMKII) substrate peptide that selectively inhibits the gibberellin (GA) response, leaving composition and slicoic acid regulatory events unaffected.
T18543	Phthalimide-PEG4-MPDM-OH	Others	Others
	Phthalimide-PEG4-MPDM-OH, a PROTAC linker with a PEGs composition, has applications in the synthesis of various PROTACs. These PROTACs consist of a linker connecting two distinct ligands: one binds to an E3 ubiquitin ligase, while the other binds to the target protein. By leveraging the intracellular ubiquitin-proteasome system, PROTACs selectively induce the degradation of target proteins [1].
T40889	DMNB-caged-Serine	Others	Others
	DMNB-caged-Serine is a photocaged amino acid . DMNB is a caging group which is sensitive to blue light. DMNB-caged-Serine can be incorporated into proteins in Saccharomyces cerevisiae in response to the amber nonsense codon TAG, which can be helpful for controlling the chemical composition of mammalian proteins..
T84733	C24-Ceramide	Others	Others
	C24-Ceramide，一种参与构成脂质膜的鞘磷脂，具有诱导膜特性时间依赖性变化及促进膜重组的功能。
T76415L	Asp-Asp-Asp-Asp-Asp-Asp TFA
	Asp-Asp-Asp-Asp-Asp-Asp TFA，一种以聚天冬氨酸形式出现的化合物，与流感病毒神经氨酸酶的催化位点和抗原位点具有特异性关联，此关联取决于特定氨基酸的数量。
T18493	NH2-PEG5-C6-Cl	Others	Others
	NH2-PEG5-C6-Cl (K-7) is a PROTAC linker, which refers to the PEG composition. NH2-PEG5-C6-Cl can be used in the synthesis of a series of PROTACs, and it induces degradation of intracellular molecules by autophagy[1].
T37070	Pyridomycin	Others	Others
	Pyridomycin is a structurally unusual antimycobacterial cyclodepsipeptide whose composition includes two rare moieties: 3-(3-pyridyl)-L-alanine and 2-hydroxy-3-methylpent-2-enoic acid. It inhibits NADH-dependent enoyl (Acyl-Carrier-Protein) reductase InhA, preventing mycolic acid synthesis in M. tuberculosis, including isoniazid-resistant strains (MICs = 0.31-0.63 μg/ml).
T39265	Idroxioleic acid (R)-2-Hydroxyoleic acid,(R)-2-OHOA	Others	Others
	Idroxioleic acid ((R)-2-Hydroxyoleic acid; (R)-2-OHOA) is the R enantiomer of (Rac)-Idroxioleic acid. It is an orally active fatty acid known for its ability to modulate the lipid composition and structure of membranes. With demonstrated antitumor activities, Idroxioleic acid plays a significant role in the field of cancer research.
T17689	Boc-Pip-alkyne-Ph-COOH	Others	Others
	Boc-Pip-alkyne-Ph-COOH, a PROTAC linker characterized by its alkyl/ether composition, plays a crucial role in synthesizing PROTACs including ARD-266. This compound demonstrates significant efficacy in promoting the degradation of androgen receptor (AR) protein across AR-positive prostate cancer cell lines such as LNCaP, VCaP, and 22Rv1, showcasing DC50 values ranging from 0.2-1 nM[1].
T37124	1,3-Dipalmitoleoyl-rac-glycerol	Others	Others
	1,3-Dipalmitoleoyl-rac-glycerol is a diacylglycerol with palmitoleic acid at the sn-1 and sn-3 positions. It selectively inhibits α-glucosidase from S. cerevisiae over rat enzyme (IC50s = 4.45 and 9,326.5 μM, respectively). 1,3-Dipalmitoleoyl-rac-glycerol has been used in the formation of lipid bilayers to study the effects of membrane composition and the ionophore valinomycin on membrane potential.
T17133	Tos-PEG4-t-butyl ester Tos-PEG4-Boc	Others	Others
	Tos-PEG4-t-butyl ester (Tos-PEG4-Boc) is a PROTAC linker characterized by its PEG composition. This compound plays a crucial role in the synthesis of a range of PROTACs, including BI-3663, a highly selective PTK2/FAK PROTAC. It employs cereblon ligands to target E3 ligases for the degradation of PTK2, exhibiting potent inhibitory activity with an IC50 of 18 nM[1].
T76885	Sonelokimab
	Sonelokimab (ALX 0761; M 1095) 是三价纳米抗体，特异性结合人白介素(IL)-17A、IL-17F及人血清白蛋白VHH，由单价骆驼来源纳米抗体构成，展现于斑块型银屑病研究中的应用潜力。
T37711	δ2-cis-Hexadecenoic Acid	Others	Others
	One of the first organisms in which quorum sensing was observed were Myxobacteria, a group of gram-negative bacteria, found mainly in soil and also common to marine and freshwater systems. The cellular membranes of autotrophic bacteria contain mono-unsaturated fatty acids. The specific composition and abundance of membrane fatty acids can be used to identify specific genera of bacterial populations in natural environments (e.g., mining lakes, etc.). δ2-cis-Hexadecenoic acid is an unusual fatty a...
T82667	CRT0063465	Others	Others
	CRT0063465是一种同时针对人类PGK1和Stress Sensor DJ1的配体，其对PGK1的Kd值为24 μM。该化合物能够调节端粒蛋白复合体的形成及端粒长度。
T81305	ReAsH-EDT2
	ReAsH-EDT2为膜透性红色荧光染料，专用于蛋白质标记。作为二砷化合物，其通过共价结合至四半胱氨酸序列实现蛋白质成像，并可监测其定位与转运。(λex=530 nm，λem=592 nm)。
T76585	Hepcidin-20 (human)
	Hepcidin-20 (human) 是一种β-折叠结构肽，含有组氨酸和丰富的半胱氨酸，具备抗真菌活性，并能抑制多糖细胞间粘附素 (PIA) 阳性及阴性菌株的生物膜形成及细菌细胞代谢[3]。
TP1249	Adrenocorticotropic Hormone (ACTH) (1-39), rat ACTH (1-39) (mouse, rat)
	Adrenocorticotropic Hormone (ACTH) (1-39), rat is a potent melanocortin 2 (MC2) receptor agonist.Peptide fragments of ACTH (1-39) were formed during in vitro incubation of the peptide with membrane preparations. ACTH (1-39) were isolated by high pressure
T85147	Sterculic Acid methyl ester SFE 20:2,Methyl Sterculate	Others	Others
	Sterculic acid methyl ester, an ester derivative of sterculic acid known for inhibiting Δ9 desaturase, has been found to adversely affect and exhibit toxicity towards R. opacus bacteria at a concentration of 0.75 mM. It not only hampers bacterial growth but also modifies fatty acid composition by reducing stearate and oleate levels, increasing the palmitate ratio, and decreasing overall fatty acid content at 0.25 or 0.5 mM concentrations. Additionally, at 50 ppm, Sterculic acid methyl ester enha...
T36454	1-Stearoyl-rac-glycerol Glyceryl monostearate,Monostearin
	1-Stearoyl-rac-glycerol 是一种在 sn-1 位含有硬脂酸的单酰甘油。在偶氮甲烷诱发的小鼠结肠直肠癌模型中，肿瘤组织中的 1-Stearoyl-rac-glycerol水平降低。1-Stearoyl-rac-glycerol 已被用于大鼠透皮递送阿霉素的传递体的组成，导致阿霉素在淋巴结、脾脏和心脏中积聚。
T36698	9(Z),11(E),13(E)-Octadecatrienoic Acid	Others	Others
	9(Z),11(E),13(E)-Octadecatrienoic Acid (α-ESA) is a conjugated polyunsaturated fatty acid commonly found in plant seed oil. This fatty acid accounts for about 60% of the total fatty acid composition of bitter gourd seed oil and about 70% in tung oil. α-ESA is metabolized and converted to conjugated linoleic acid (9Z,11E-CLA) in rats. It has shown potential as a tumor growth suppressor. In colon cancer Caco-2 cells, α-ESA induced apoptosis through up-regulation of GADD45, p53, and PPARγ. In DLD-1...
T38208	Heneicosapentaenoic Acid	Others	Others
	Heneicosapentaenoic Acid (HPA) is a 21:5 ω-3 fatty acid present in trace amounts in the green alga B. pennata and in fish oils. Its chemical composition is similar to eicosapentaenoic acid (EPA) except elongated with one carbon on the carboxyl end, placing the first double bond in the δ6 position. HPA can be used to study the significance of the position of the double bonds in ω-3 fatty acids. It incorporates into phospholipids and into triacylglycerol in vivo with the same efficiency as EPA and...
T68219	Peraclopone	Others	Others
	Peraclopone is a hypolidemic drug. It is an inhibitor of 7-Dehydrocholesterol reductase. Peraclopone potently inhibits the final step in cholesterol biosynthesis. Feeding this agent to rats leads to a rapid replacement of membrane cholesterol with its immediate precursor 7-dehydrocholesterol, and a dramatic reduction in plasma sterol concentration. Peraclopone caused a dose-dependent decrease in cholesterol and a concomitant accumulation of provitamin D3 (7-dehydrocholesterol) in the skin, which...
T36889	Methyl alpha-eleostearate	Others	Others
	Methyl alpha-eleostearate (α-ESA) is a conjugated polyunsaturated fatty acid commonly found in plant seed oil. This fatty acid accounts for about 60% of the total fatty acid composition of bitter gourd seed oil and about 70% in tung oil. α-ESA is metabolized and converted to conjugated linoleic acid (9Z,11E-CLA) in rats. It has shown potential as a tumor growth suppressor. In colon cancer Caco-2 cells, α-ESA induced apoptosis through up-regulation of GADD45, p53, and PPARγ. In DLD-1 cells supple...
T36888	9(Z),11(E),13(E)-Octadecatrienoic Acid ethyl ester	Others	Others
	9(Z),11(E),13(E)-Octadecatrienoic Acid ethyl ester (α-ESA) is a conjugated polyunsaturated fatty acid commonly found in plant seed oil. This fatty acid accounts for about 60% of the total fatty acid composition of bitter gourd seed oil and about 70% in tung oil. α-ESA is metabolized and converted to conjugated linoleic acid (9Z,11E-CLA) in rats. It has shown potential as a tumor growth suppressor. In colon cancer Caco-2 cells, α-ESA induced apoptosis through up-regulation of GADD45, p53, and PPA...
T37383	1,2,3-Trilinoelaidoyl-rac-glycerol	Others	Others
	1,2,3-Trilinoelaidoyl-rac-glycerol is a triacylglycerol that contains linoelaidic acid at the sn-1, sn-2, and sn-3 positions. Dietary administration of 1,2,3-trilinoelaidoyl-rac-glycerol (0.6-6.3% w/w) lowers serum levels of thromboxane B2 , prostaglandin F2 (PGF2), and PGE in rats.1 \|1. Bruckner, G., Goswami, S., and Kinsella, J.E. Dietary trilinoelaidate: Effects on organ fatty acid composition, prostanoid biosynthesis and platelet function in rats. J. Nutr. 114(1), 58-67 (1984).
T38172	RO 5263397 hydrochloride	Others	Others
	Potent trace amine 1 (TA1) receptor agonist (EC50 values are 0.12, 35 and 17-85 nM for mouse, rat and human receptors, respectively). Increases wakefulness and reduces REM and NREM sleep duration in wild type mice. Inhibits spontaneous locomotor activity in dopamine transport (DAT) knockout mice. Espinoza et al (2018) Biochemical and functional characterization of the trace amine-associated receptor 1 (TAAR1) agonist RO5263397. Front.Pharmacol. 9 645 PMID:29977204 \|Galley et al (2015) Discovery ...
T35757	Beauvericin A	Others	Others
	Beauvericin A is a cyclodepsipeptide and derivative of beauvericin originally isolated fromB. bassianathat has diverse biological activities.1,2,3It is active againstM. tuberculosis(MIC = 25 μg/ml) andP. falciparum(IC50= 12 μg/ml).2Beauvericin A is toxic to brine shrimp (LD100= 32 μg/ml).3 1.Gupta, S., Montillor, C., and Hwang, Y.-S.Isolation of Novel Beauvericin Analogues from the Fungus Beauveria bassianaJ. Nat. Prod.58(5)733-738(1995) 2.Nilanonta, C., Isaka, M., Kittakoop, P., et al.Antimycob...

化合物

tert-Butyl 11-aminoundecanoate

Cat.No: T18788

Target: PROTAC Linker

Cat.No: T9614

Target: SARS-CoV

Diethyltoluamide

Cat.No: T0731

Synonym: N,N-Diethyl-m-toluamide,避蚊胺,DEET,N,N-Diethyl-meta-toluamide,Delphene,避蚊胺（DEET）

Target: AChE, Parasite

Retagliptin Phosphate

Cat.No: T12710

Synonym: SP 2086,瑞格列汀磷酸盐

Target: Proteasome, DPP-4

Monoethyl pimelate

Cat.No: T18363

Target: Others, PROTAC Linker

Br-C10-methyl ester

Cat.No: T17694

Synonym: 11-溴代十一烷酸甲酯

Target: Others, PROTAC Linker

Cat.No: T35353

Synonym: dichlorophenyl imidazoldioxolan,新康唑

Target: Antibacterial

Butoconazole nitrate

Cat.No: T1438

Synonym: RS 35887,硝酸布康唑

Target: Estrogen/progestogen Receptor, Antifungal

Cat.No: T27015

Target: Others

7-Deaza-7-propargylamino-ddATP

Cat.No: T38532

Target: Others

Cat.No: T33918

Synonym: Hortox,Niagara 4512,Solane,Dutom,FMC 4512

Target: Others

2-Methyldecanenitrile

Cat.No: T21189

Synonym: 2-Cyanodecane

Target: Others

Decamethylene glycol

Cat.No: T21096

Synonym: alpha,omega-Decanediol,Decamethylenediol,1,10-Dihydroxydecane,Decane-1,10-diol

Target: Others

2-Myristyldistearin

Cat.No: T85050

Synonym: TG(18:0/14:0/18:0),1,2-Stearin-2-Myristin

Target: Others

8(Z)-Eicosenoic Acid

Cat.No: T85288

Synonym: cis-8-Eicosenoic Acid

Target: Others

PTD-p65-P1 Peptide

Cat.No: TP1608

Scrambled TRAP Fragment

Cat.No: T38743

S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate

Cat.No: T18653

Synonym: s-1-hydroxy-2-methylpropan-2-yl-methanesulfonothioate

Target: Others, ADC Linker

Syntide 2 (TFA) (108334-68-5 free base)

Cat.No: TP1347

Synonym: Syntide 2 (TFA)

Phthalimide-PEG4-MPDM-OH

Cat.No: T18543

Target: Others

DMNB-caged-Serine

Cat.No: T40889

Target: Others

Cat.No: T84733

Target: Others

Asp-Asp-Asp-Asp-Asp-Asp TFA

Cat.No: T76415L

Cat.No: T18493

Target: Others

Cat.No: T37070

Target: Others

Idroxioleic acid

Cat.No: T39265

Synonym: (R)-2-Hydroxyoleic acid,(R)-2-OHOA

Target: Others

Boc-Pip-alkyne-Ph-COOH

Cat.No: T17689

Target: Others

1,3-Dipalmitoleoyl-rac-glycerol

Cat.No: T37124

Target: Others

Tos-PEG4-t-butyl ester

Cat.No: T17133

Synonym: Tos-PEG4-Boc

Target: Others

Cat.No: T76885

δ2-cis-Hexadecenoic Acid

Cat.No: T37711

Target: Others

Cat.No: T82667

Target: Others

Cat.No: T81305

Hepcidin-20 (human)

Cat.No: T76585

Adrenocorticotropic Hormone (ACTH) (1-39), rat

Cat.No: TP1249

Synonym: ACTH (1-39) (mouse, rat)

Sterculic Acid methyl ester

Cat.No: T85147

Synonym: SFE 20:2,Methyl Sterculate

Target: Others

1-Stearoyl-rac-glycerol

Cat.No: T36454

Synonym: Glyceryl monostearate,Monostearin

9(Z),11(E),13(E)-Octadecatrienoic Acid

Cat.No: T36698

Target: Others

Heneicosapentaenoic Acid

Cat.No: T38208

Target: Others

Cat.No: T68219

Target: Others

Methyl alpha-eleostearate

Cat.No: T36889

Target: Others

9(Z),11(E),13(E)-Octadecatrienoic Acid ethyl ester

Cat.No: T36888

Target: Others

1,2,3-Trilinoelaidoyl-rac-glycerol

Cat.No: T37383

Target: Others

RO 5263397 hydrochloride

Cat.No: T38172

Target: Others

Cat.No: T35757

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T4S0554	Theaflavine-3,3'-digallate TFBG,theaflavin digallate,3,3’-二没食子酸酯茶黄素	Others	Others
	Theaflavine-3,3'-digallate (theaflavin digallate) 和乳酸一起可以减少单纯疱疹病毒的传播。
T0344L	Miconazole nitrate NSC 169434 Nitrate,硝酸咪康唑,R18134 nitrate	Antibacterial; Antibiotic; Antifungal	Microbiology/Virology
	Miconazole nitrate (R18134 nitrate) 是咪唑类可抗菌的抗真菌剂。
T3237	Lecithin Phospholutein,卵磷脂,L-α-磷脂酰胆碱,L-α-Phosphatidylcholine,Phosphatidylcholines	Others; Endogenous Metabolite	Metabolism; Others
	Lecithin (L-α-Phosphatidylcholine) 被认为是安全的常规磷脂源。磷脂能够改变动物细胞膜的脂肪酸组成和微观结构。
T5087	DL-Isocitric acid trisodium salt 异柠檬酸三钠盐,Isocitric acid trisodium salt	Others; Endogenous Metabolite	Metabolism; Others
	DL-Isocitric acid trisodium salt 是内源性代谢产物的一种。
T3243	Betaine Abromine,glycine betaine,oxyneurine,trimethylglycine,lycine,甜菜碱	Others; Endogenous Metabolite	Metabolism; Others
	Betaine (trimethylglycine) 是许多食物中发现的天然化合物，也是能够维持正常 DNA 甲基化模式的特性甲基供体。它广泛存在于植物，动物，微生物和丰富的膳食来源中。它能够促进各种肠道微生物抵抗渗透变化，从而改善微生物发酵特性。它也能够作为渗透物，通过防止脱水和渗透失活来维持禽类的细胞水和离子平衡，从而提高禽类对热应激的能力。
TN1792	Isorhamnetin 3-glucoside-7-rhamnoside	Antifection	Microbiology/Virology
	An anti-oxidative composition containing isorhamnetin-3-glucoside-7-rhamnoside (IGR)isolated from Hippophae rhamnoides L. is provided to ensure antioxidative, antibacterial, and anti-cancer effect.
T10197	8,9-Epoxy-3-isobutyryloxy-10-(2-methylbutanoyl)thymol 8,9-环氧-3-异丁酰-10-(2-甲基丁酰) 百里草酚,8-9-epoxy-3-isobutyryloxy-10-2-methylbutanoyl-thymol	Others	Others
	8,9-Epoxy-3-isobutyryloxy-10-(2-methylbutanoyl)thymol is a chemical composition of essential oils from Telekia speciosa. It also shows marked antipro-liferative activity against human cancer cell lines in vitro.
T81094	Steppogenin-7,4'-di-O-β-D-glucoside
	Steppogenin-7,4'-di-O-β-D-glucoside, 一种从Morus nigra根部提取的天然化合物。
TMA1008	Ganoderic acid S	Others	Others
	A novel combination of triterpenoids includes at least ganoderic acid S (GAS), ganoderic acid T (GAT), ganoderic acid Me (GAMe), ganoderic acid R (GAR), and ganodermic acid S (GMAS), the composition is suitable for the treatment or prophylaxis of colon ca
T36348	Cerebroside C	Others	Others
	Cerebroside C is a fungal metabolite and glycosphingolipid that has been found in the rice pathogenic fungusM. grisea.1It induces production of the phytoalexin momilactone A when applied to wounded rice leaves, indicating that cerebroside C is an elicitor of the hypersensitive response in rice. Cerebroside C increases germination rate and reduces germination time in wheat seeds in a concentration-dependent manner at 4°C.2It also increases root length, fresh weight, and dry weight of wheat seedli...

天然产物

Theaflavine-3,3'-digallate

Cat.No: T4S0554

Synonym: TFBG,theaflavin digallate,3,3’-二没食子酸酯茶黄素

Target: Others

Miconazole nitrate

Cat.No: T0344L

Synonym: NSC 169434 Nitrate,硝酸咪康唑,R18134 nitrate

Target: Antibacterial, Antibiotic, Antifungal

Cat.No: T3237

Synonym: Phospholutein,卵磷脂,L-α-磷脂酰胆碱,L-α-Phosphatidylcholine,Phosphatidylcholines

Target: Others, Endogenous Metabolite

DL-Isocitric acid trisodium salt

Cat.No: T5087

Synonym: 异柠檬酸三钠盐,Isocitric acid trisodium salt

Target: Others, Endogenous Metabolite

Cat.No: T3243

Synonym: Abromine,glycine betaine,oxyneurine,trimethylglycine,lycine,甜菜碱

Target: Others, Endogenous Metabolite

Isorhamnetin 3-glucoside-7-rhamnoside

Cat.No: TN1792

Target: Antifection

8,9-Epoxy-3-isobutyryloxy-10-(2-methylbutanoyl)thymol

Cat.No: T10197

Synonym: 8,9-环氧-3-异丁酰-10-(2-甲基丁酰) 百里草酚,8-9-epoxy-3-isobutyryloxy-10-2-methylbutanoyl-thymol

Target: Others

Steppogenin-7,4'-di-O-β-D-glucoside

Cat.No: T81094

Ganoderic acid S

Cat.No: TMA1008

Target: Others

Cat.No: T36348

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-01471	Activin A Protein, Human, Mouse, Rat, Cynomolgus, Rhesus, Recombinant Activin A,INHBA,Inhibin beta A chain,Inhibin β A chain	Human/Mouse/Rat	HEK293 Cells
	Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. Activins, members of the TGF-beta superfamily, are disulfide-linked dimeric proteins originally purified from gonadal fluids as proteins that stimulated pituitary follicle stimulating hormone (FSH) release. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell developm...
TMPK-00958	BTN1A1 Protein, Human, Recombinant (His & Avi) BT,BTN,Butyrophilin,BTN1A1	Human	HEK293 Cells
	Butyrophilin 1A1 (BTN1A1) is one of the membrane proteins that surrounds LD,BTN1A1 plays an important role in regulating LD synthesis via a mechanism involving membrane phospholipid composition.
TMPK-00764	Apolipoprotein A-II/APOA2 Protein, Human, Recombinant (hFc) Apolipoprotein A-II(1-76),Apolipoprotein A-II,Apo-AII,APOA2,...	Human	HEK293 Cells
	APOA2 is a protein implicated in triglyceride, fatty acid and glucose metabolism. In pigs, the APOA2 gene is located on pig chromosome 4 (SSC4) in a QTL region affecting fatty acid composition, fatness and growth traits. Apolipoprotein A-II/APOA2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 36.1 kDa and the accession number is P02652.
TMPK-00795	Apolipoprotein A-II/APOA2 Protein, Mouse, Recombinant (hFc) APOA2,Apolipoprotein A-II(1-76),Apolipoprotein A-II,Apolipop...	Mouse	HEK293 Cells
	APOA2 is a protein implicated in triglyceride, fatty acid and glucose metabolism. In pigs, the APOA2 gene is located on pig chromosome 4 (SSC4) in a QTL region affecting fatty acid composition, fatness and growth traits. Apolipoprotein A-II/APOA2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 36.2 kDa and the accession number is P09813.
TMPH-02206	TLCD1 Protein, Human, Recombinant (His) TLC domain-containing protein 1,TLCD1,Calfacilitin	Human	E. coli
	Regulates the composition and fluidity of the plasma membrane. Inhibits the incorporation of membrane-fluidizing phospholipids containing omega-3 long-chain polyunsaturated fatty acids (LCPUFA) and thereby promotes membrane rigidity. Does not appear to have any effect on LCPUFA synthesis. TLCD1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 26.1 kDa and the accession number is Q96CP7.
TMPH-00039	Single-strand DNA-binding protein Protein, Agrobacterium fabrum, Recombinant (His & Myc) Single-strand DNA-binding protein,63.5 kDa virulence protein...	Agrobacterium fabrum	E. coli
	Involved in DNA transformation; mediates the nuclear uptake of single-stranded DNA copies of the transferred DNA (T-DNA) element. Binds single-stranded but not double-stranded DNA regardless of nucleotide sequence composition. Single-strand DNA-binding protein Protein, Agrobacterium fabrum, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 70.3 kDa and the accession number is P08062.
TMPJ-01016	INHBC Protein, Human, Recombinant (N-His) Activin Beta-C Chain,INHBC,Inhibin β C Chain,Activin β-C Cha...	Human	E. coli
	Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins,Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary...
TMPH-01607	LCE3A Protein, Human, Recombinant (His) Late envelope protein 13,LCE3A,Late cornified envelope prote...	Human	E. coli
	A structural component of the cornified envelope of the stratum corneum involved in innate cutaneous host defense (Probable). Possesses defensin-like antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative bacteria, both aerobic and anaerobic species. Upon inflammation, may regulate skin barrier repair by shaping cutaneous microbiota composition and immune response to bacterial antigens. LCE3A Protein, Human, Recombinant (His) is expressed in E. coli expression system ...
TMPH-01530	INHBA Protein, Human, Recombinant (His & SUMO) Activin beta-A chain,INHBA,Inhibin beta A chain,Erythroid di...	Human	E. coli
	Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of a...
TMPJ-00507	EIF4E Protein, Human, Recombinant eIF-4F 25 kDa subunit,EIF4F,eIF-4E,Eukaryotic translation in...	Human	E. coli
	Eukaryotic translation initiation factor 4E is a 217 amino acids protein that belongs to the eukaryotic initiation factor 4E family. eIF4F is a multi-subunit complex, the composition of which varies with external and internal environmental conditions. It is composed of at least EIF4A, EIF4E and EIF4G1/EIF4G3. EIF4E is also known to interact with other partners.It can recognize and bind the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facil...
TMPH-01394	GRIN1 Protein, Human, Recombinant (His) N-methyl-D-aspartate receptor subunit NR1,Glutamate [NMDA] r...	Human	E. coli
	Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition. GRIN1 Protein, Human, Recombinant (His)...
TMPH-02079	SPTLC2 Protein, Human, Recombinant (His & SUMO) Long chain base biosynthesis protein 2a,Long chain base bios...	Human	E. coli
	Serine palmitoyltransferase (SPT). The heterodimer formed with LCB1/SPTLC1 constitutes the catalytic core. The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. The SPTLC1-SPTLC2-SPTSSA complex shows a strong preference for C16-CoA substrate, while the SPTLC1-SPTLC2-SPTSSB complex displays a preference for C18-CoA substrate. Plays an important role in de novo sphyngolipid biosynthesis which is crucial for adipogenesis. SPTLC2 Protein, Human, Recomb...
TMPH-02331	GLRA1 Protein, Human, Recombinant (His & Myc) Glycine receptor subunit alpha-1,GLRA1,Glycine receptor stry...	Human	E. coli
	Glycine receptors are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine. Channel opening is also triggered by taurine and beta-alanine. Channel characteristics depend on the subunit composition; heteropentameric channels are activated by lower glycine levels and display faster desensitization. Plays an important role in the down-regulation of neuronal excitability. Contributes to the generation of inhibitory postsynaptic currents. Channel activity is potentiat...
TMPJ-00761	FTH Protein, Human, Recombinant (His) FTHL6,Cell proliferation-inducing gene 15 protein,Ferritin h...	Human	E. coli
	Ferritin heavy polypeptide 1(FTH1), is a ubiquitous intracellular protein which stores iron in a soluble, non-toxic, readily available form. FTH1 has ferroxidase activity and is important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Ferritin is composed of 24 subunits of the light and heavy ferritin chains. It plays a role in delivery of iron to cells and mediates iron uptake in capsule cells of the developing kidney. Variation of...
TMPY-04770	RIOK1 Protein, Human, Recombinant (His & GST) AD034,RRP10,bA288G3.1,RIO kinase 1	Human	Baculovirus Insect Cells
	RIOK1, also known as RIO kinase 1, is a member of the RIO family of atypical serine protein kinases first characterized in yeast. RIOK1 and RIOK2 proteins are present in organisms from Archaea to humans. RIOK1 functions as a new interactor of protein arginine methyltransferase 5 (PRMT5), competes with pICln for binding and modulates PRMT5 complex composition and substrate specificity. RioK1 and pICln bind to PRMT5 in a mutually exclusive fashion. This results in a PRMT5-WD45/MEP5 core structure ...
TMPY-05438	CAN F 4 Protein, Canine, Recombinant (His)	Canine	HEK293 Cells
	Dog dander is an important cause of respiratory allergy but its content of allergenic components is still incompletely known. The size and the amino acid composition of the ligand-binding pocket indicate that Can f 4 is capable of binding only relatively small hydrophobic molecules which are different from those that Can f 2 is able to bind. The crystal structure of Can f 4 contained both monomeric and dimeric forms of the allergen, suggesting that Can f 4 is able to form transient (weak) dimers...
TMPY-02711	Ferritin heavy chain 1/FTH1 Protein, Human, Recombinant FHC,FTHL6,FTH,PIG15,PLIF,ferritin, heavy polypeptide 1,HFE5	Human	E. coli
	FTH1 (ferritin, heavy polypeptide 1) is the heavy subunit of ferritin which is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative dis...
TMPH-02539	MGAT3 Protein, Mouse, Recombinant (His & Myc) Mgat3,Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosam...	Mouse	E. coli
	It is involved in the regulation of the biosynthesis and biological function of glycoprotein oligosaccharides. Catalyzes the addition of N-acetylglucosamine in beta 1-4 linkage to the beta-linked mannose of the trimannosyl core of N-linked sugar chains, called bisecting N-acetylglucosamine (GlcNAc). It is one of the most important enzymes involved in the regulation of the biosynthesis of glycoprotein oligosaccharides. The addition of this bisecting GlcNAc residue alters not only the composition,...
TMPH-02217	SMARCA4 Protein, Human, Recombinant (His) Transcription activator BRG1,Protein brahma homolog 1,SWI/SN...	Human	P. pastoris (Yeast)
	Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating the calcium-dependent release of a repressor compl...

重组蛋白

Activin A Protein, Human, Mouse, Rat, Cynomolgus, Rhesus, Recombinant

Cat.No: TMPJ-01471

Species: Human/Mouse/Rat

Expression System: HEK293 Cells

BTN1A1 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00958

Species: Human

Expression System: HEK293 Cells

Apolipoprotein A-II/APOA2 Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00764

Species: Human

Expression System: HEK293 Cells

Apolipoprotein A-II/APOA2 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPK-00795

Species: Mouse

Expression System: HEK293 Cells

TLCD1 Protein, Human, Recombinant (His)

Cat.No: TMPH-02206

Species: Human

Expression System: E. coli

Single-strand DNA-binding protein Protein, Agrobacterium fabrum, Recombinant (His & Myc)

Cat.No: TMPH-00039

Species: Agrobacterium fabrum

Expression System: E. coli

INHBC Protein, Human, Recombinant (N-His)

Cat.No: TMPJ-01016

Species: Human

Expression System: E. coli

LCE3A Protein, Human, Recombinant (His)

Cat.No: TMPH-01607

Species: Human

Expression System: E. coli

INHBA Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01530

Species: Human

Expression System: E. coli

EIF4E Protein, Human, Recombinant

Cat.No: TMPJ-00507

Species: Human

Expression System: E. coli

GRIN1 Protein, Human, Recombinant (His)

Cat.No: TMPH-01394

Species: Human

Expression System: E. coli

SPTLC2 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-02079

Species: Human

Expression System: E. coli

GLRA1 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-02331

Species: Human

Expression System: E. coli

FTH Protein, Human, Recombinant (His)

Cat.No: TMPJ-00761

Species: Human

Expression System: E. coli

RIOK1 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04770

Species: Human

Expression System: Baculovirus Insect Cells

CAN F 4 Protein, Canine, Recombinant (His)

Cat.No: TMPY-05438

Species: Canine

Expression System: HEK293 Cells

Ferritin heavy chain 1/FTH1 Protein, Human, Recombinant

Cat.No: TMPY-02711

Species: Human

Expression System: E. coli

MGAT3 Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02539

Species: Mouse

Expression System: E. coli

SMARCA4 Protein, Human, Recombinant (His)

Cat.No: TMPH-02217

Species: Human

Expression System: P. pastoris (Yeast)

Cat. No.	Product Name	Target	Signaling Pathways
T35790	Palmitic acid-1,2,3,4-13C4 Palmitic Acid-13C (C1, C2, C3, and C4 labeled)
	Palmitic acid-13C (C1, C2, C3, and C4 labeled) is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid is a common 16-carbon saturated fat that represents 10-20% of human dietary fat intake and comprises approximately 25 and 65% of human total plasma lipids and saturated fatty acids, respectively.1,2Acylation of palmitic acid to proteins facilitates anchoring of membrane-bound proteins to the lipid bilayer and trafficking of intracellula...
T35789	Palmitic acid-1-13C
	Palmitic acid-13C is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid is a 16-carbon saturated fatty acid. It comprises approximately 25% of human total plasma lipids.1 It increases protein levels of COX-2 in RAW 264.7 cells when used at a concentration of 75 μM.2 Palmitic acid is involved in the acylation of proteins to anchor membrane-bound proteins to the lipid bilayer.2,3,4,5,6 \|1. Santos, M.J., López-Jurado, M., Llopis, J., et a...
T35791	Palmitic acid-13C
	Palmitic acid-13C is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid-13C contains 13C at the C2 position and has been used in the study of free fatty acid incorporation into phospholipid fatty acids in soil microbes.1 Palmitic acid is a 16-carbon saturated fatty acid. It comprises approximately 25% of human total plasma lipids.2 It increases protein levels of COX-2 in RAW 264.7 cells when used at a concentration of 75 μM.3 Palmitic ...

同位素标记化合物

Palmitic acid-1,2,3,4-13C4

Cat.No: T35790

Synonym: Palmitic Acid-13C (C1, C2, C3, and C4 labeled)

Palmitic acid-1-13C

Cat.No: T35789

Palmitic acid-13C

Cat.No: T35791

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