首页 工具
登录
购物车

搜索结果

Search Results for " glut4 "
Targets Recommended: transporter

32

抑制剂 & 化合物

9

天然产物

2

重组蛋白

1

同位素标记化合物

如果没找到您满意的产品或者您对产品有其他要求,可以联系我们专业顾问为您提供针对性的合理建议。     QQ咨询       网站留言咨询

提交您的定制咨询

点击图片重新获取验证码
Cat. No. Product Name Target Signaling Pathways
T61695 GLUT4-IN-2

transporter Metabolism
GLUT4-IN-2 是一种特异性 GLUT4 抑制剂,抑制 GLUT1 和 GLUT4GLUT4-IN-2 具有抗肿瘤活性,诱导细胞凋亡 (apoptosis) 和细胞周期停滞,可用于研究癌症。
T11420 GLUT4 activator 1

Others Others
GLUT4 activator 1 is a potent glucose transporter type 4 (GLUT4) translocation activator (EC50: 0.14 μM).
T9558 KL-11743

transporter Metabolism
KL-11743 是葡萄糖竞争性 I 类葡萄糖转运蛋白抑制剂,口服有活性,能够抑制GLUT1 (IC50:115 nM) 、GLUT2 (IC50:137 nM) 、GLUT3 (IC50:90 nM) 及GLUT4 (IC50:68 nM) 。它能够特异性阻断葡萄糖代谢,也可与电子传递抑制剂协同作用诱导细胞死亡。
TP1993L M617 acetate

Neuropeptide Y Receptor GPCR/G Protein; Neuroscience
M617 acetate 是甘丙肽受体 1 (GAL1) 的选择性激动剂。 M617 acetate 通过中枢 GAL1 起作用,促进 GLUT4 表达,并提高 2 型糖尿病大鼠心肌中的 GLUT4 含量。 GAL1 和 GAL2 的 Ki 值分别为 0.23 和 5.71 nM。
T33412 MitoPQ

MitoParaquat

Glucokinase; transporter Metabolism
MitoPQ (MitoParaquat) 是一个线粒体靶向的小分子化合物。MitoPQ 选择性加强线粒体超氧化物和过氧化氢的含量,抑制胰岛素刺激的葡萄糖摄取和葡萄糖转运蛋白 4 (GLUT4) 向脂肪细胞和肌管中质膜的易位。MitoPQ 可用于研究线粒体氧化应激与调节的 GLUT4 转运。
T3713 BAY-876

transporter Metabolism
BAY-876 是口服有效的,选择性的葡萄糖转运蛋白 1 (GLUT1) 抑制剂(IC50= 2 nM)。BAY-876 对 GLUT1 选择性比 GLUT2,GLUT3 和 GLUT4 高(>130 倍)。BAY-876 对糖酵解代谢和卵巢癌生长也有有效的抑制作用。
T8616 Fasentin

N-[4-chloro-3-(trifluoromethyl)phenyl]-3-oxobutanamide

transporter Metabolism
Fasentin (N-[4-chloro-3-(trifluoromethyl)phenyl]-3-oxobutanamide) 是葡萄糖摄取抑制剂,可抑制GLUT-1/GLUT-4转运蛋白,优先抑制 GLUT4,IC50为 68 μM。它是死亡受体刺激敏化剂,可敏化细胞对 FAS 诱导的细胞死亡,具有抗血管生成活性。
TP2312 MOTS-c(Human) Acetate(1627580-64-6 free)

Others; AMPK Chromatin/Epigenetic; Others; PI3K/Akt/mTOR signaling
MOTS-c(Human) Acetate(1627580-64-6 free)是一种线粒体衍生肽。 它诱导 AMP 类似物 AICAR 的积累,增加 AMPK 的激活和其下游 GLUT4 的表达。它可诱导葡萄糖摄取并提高胰岛素敏感性。 它对调节肥胖、糖尿病、运动和长寿有重要意义。
T8732 CTPI-2

Others; Mitochondrial Metabolism Metabolism; Others
CTPI-2 是一种特异性线粒体柠檬酸盐载体SLC25A1抑制剂,KD=3.5 μM,具有抗肿瘤作用。它能够抑制糖酵解、PPARγ 及其下游靶点葡萄糖转运蛋白 GLUT4。它阻断非酒精性脂肪性肝炎逆转脂肪变性的显著改变,防止演变为脂肪性肝炎,减少肝脏和脂肪组织中炎性巨噬细胞的浸润,并显著减轻由高脂肪饮食引起的肥胖。
T75817 M617 TFA

M617 TFA 是一种选择性甘丙肽受体 1(GAL1)激动剂,对 GAL1 和 GAL2 的 Ki 分别为 0.23 和 5.71 nM。M617 TFA 通过其中枢 GAL1 作用,促进 2 型糖尿病大鼠心肌 GLUT4的表达,提高 GLUT4的含量。
T76039 MOTS-c(human) acetate

MOTS-c(human) acetate 是一种线粒体衍生的肽,可诱导 AMP 类似物AICAR 的积累,增加AMPK 的激活及其下游GLUT4的表达。MOTS-c(human) acetate 可诱导葡萄糖摄取并改善胰岛素敏感性,对肥胖,糖尿病,运动和长寿的调节具有影响。
T84422 13-OAHSA

Others Others
13-OAHSA, a branched fatty acid ester of hydroxy fatty acids (FAHFAs), results from the esterification of oleic acid to 13-hydroxy stearic acid. It represents a significant component of the FAHFA family, most abundantly expressed in the serum of glucose-tolerant AG4OX mice that exhibit adipose tissue-specific overexpression of the Glut4 glucose transporter. Similar to other FAHFAs which are known to enhance glucose tolerance, stimulate insulin secretion, and exert anti-inflammatory effects, 13-O...
T36142 10-PAHSA

Others Others
10-PAHSA is a newly identified endogenous lipid that belongs to a collection of branched fatty acid esters of hydroxy fatty acids (FAHFAs). It is a FAHFA in which palmitic acid is esterified to 10-hydroxy stearic acid. Among the FAHFA family members, PAHSAs are the most abundant in the adipose tissue of glucose tolerant AG4OX mice, which overexpress the Glut4 glucose transporter specifically in adipose tissue. As other FAHFAs improve glucose tolerance, stimulate insulin secretion, and have anti-...
T84424 5-SAHSA

Others Others
15-SAHSA, a branched fatty acid ester of hydroxy fatty acids (FAHFAs), is recognized for its involvement in metabolic regulation. This compound comprises stearic acid esterified to 5-hydroxy stearic acid and is notably influenced by dietary changes, such as fasting and high-fat consumption, with a link to insulin sensitivity. SAHSA levels are specifically found to be moderately increased in the serum of AG4OX mice, which are characterized by their glucose tolerance through the overexpression of ...
T85300 Palmitoleic Acid sodium

C16:1(9Z),cis-Palmitoleic Acid,(9Z)-Hexadecenoic Acid,C16:1 n-7

Others Others
Palmitoleic acid, an ω-7 monounsaturated fatty acid found in macadamia and sea buckthorn oils, enhances both basal and insulin-stimulated glucose uptake, as well as Glut4 protein levels in 3T3-L1 adipocytes at a 200 µM concentration. Ex vivo, at a dosage of 300 mg/kg per day, it significantly increases glucose uptake and both aerobic and anaerobic glycolysis, while decreasing de novo fatty acid synthesis and the activity of lipogenic enzymes, specifically ATP citrate lyase (ACL) and glucose-6-ph...
T84426 5-OAHSA

Others Others
Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are endogenous lipids that are influenced by fasting and high-fat diets and linked to improved insulin sensitivity in mice. These compounds typically feature a chain of either 16 or 18 carbon atoms (for example, palmitoleic, palmitic, oleic, or stearic acid) esterified with a hydroxy fatty acid chain of similar length. One specific FAHFA, known as 5-OAHSA, consists of oleic acid bonded to the fifth carbon of hydroxy stearic acid. Within ...
T84420 13-SAHSA

Others Others
13-SAHSA, a branched fatty acid ester of hydroxy fatty acids (FAHFAs), has been found to be involved in metabolic regulation, particularly in relation to fasting, high-fat feeding, and insulin sensitivity. This compound is a synthesis of stearic acid and 13-hydroxy stearic acid. Notably, 13-SAHSA levels are found to be moderately increased in the serum of AG4OX mice, which are characterized by their glucose tolerance and expression of the Glut4 glucose transporter specifically in their adipose t...
T84387 10-SAHSA

Others Others
10-SAHSA, an endogenous lipid recently discovered, is part of the FAHFAs, a group of branched fatty acid esters of hydroxy fatty acids. It specifically consists of stearic acid esterified to 10-hydroxy stearic acid. Notably, PAHSAs, closely related to 10-SAHSA, are significantly present in the adipose tissue of AG4OX mice that are glucose tolerant due to the overexpression of the Glut4 glucose transporter in their adipose tissue. Similar to other FAHFAs, which are known to improve glucose tolera...
T84431 9-SAHSA

Others Others
Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are lipids that are modulated by dietary changes such as fasting and high-fat diets, and they play a role in insulin sensitivity. These compounds generally consist of a fatty acid chain of either 16 or 18 carbons (for example, palmitoleic, palmitic, oleic, or stearic acid) esterified to a similarly long hydroxy fatty acid. One specific FAHFA, 9-SAHSA, features stearic acid esterified at the 9th carbon of hydroxy stearic acid. The concent...
T84421 13-POHSA

Others Others
13-POHSA (palmitoleic acid esterified to 13-hydroxy stearic acid) is a type of branched fatty acid esters of hydroxy fatty acids (FAHFAs), which have recently been discovered as endogenous lipids whose levels are modulated by fasting and high-fat diets, and are linked to insulin sensitivity in mice. Notably, the concentration of 13-POHSA in the serum significantly increases in glucose tolerant AG4OX mice, a model that overexpresses the Glut4 glucose transporter in adipose tissue, suggesting its ...
T84430 12-OAHSA

Others Others
Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are recently discovered lipids that play a role in the body's response to fasting and high-fat diets, with a link to insulin sensitivity. These compounds consist of a long-chain fatty acid (such as palmitoleic, palmitic, oleic, or stearic acid) bonded to a hydroxy fatty acid, both ranging in length from C-16 to C-18. Specifically, 12-OAHSA is a type of FAHFA where oleic acid is attached to the 12th carbon of hydroxy stearic acid. Within ...
T84386 10-OAHSA

Others Others
10-OAHSA is a newly discovered endogenous lipid categorized within the group of branched fatty acid esters of hydroxy fatty acids (FAHFAs). This specific FAHFA comprises oleic acid esterified to 10-hydroxy stearic acid. It stands out among its FAHFA counterparts for its potential bioactive properties, similar to other members of its family such as PAHSAs, which are notably prevalent in the adipose tissue of AG4OX mice exhibiting glucose tolerance due to overexpression of the Glut4 glucose transp...
T84432 12-SAHSA

Others Others
Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are lipids recently discovered to be modulated by dietary influences such as fasting and high-fat feeding, and they play a role in enhancing insulin sensitivity. These compounds typically feature a carbon-16 or carbon-18 fatty acid (e.g., palmitoleic, palmitic, oleic, or stearic acid) esterified to a carbon-16 or carbon-18 hydroxy fatty acid. A specific example is 12-SAHSA, which consists of stearic acid linked to 12-hydroxy stearic acid...
T84427 9-OAHSA

Others Others
Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are a class of endogenous lipids whose levels are modulated by fasting and high-fat diets and are linked to insulin sensitivity. These compounds typically consist of a C-16 or C-18 fatty acid, such as palmitoleic, palmitic, oleic, or stearic acid, esterified to a hydroxylated C-16 or C-18 lipid. One specific form of FAHFA, known as 9-OAHSA, involves the esterification of oleic acid to 9-hydroxy stearic acid. Within the FAHFA family, OAHS...
T84407 13-PAHSA

Others Others
Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are lipids influenced by dietary changes, playing a crucial role in insulin sensitivity. These compounds typically consist of a C-16 or C-18 fatty acid (for example, palmitoleic, palmitic, oleic, or stearic acid) linked to a hydroxy fatty acid with the same carbon chain length. 13-PAHSA, a derivative where palmitic acid is esterified to 13-hydroxy stearic acid, is notably prevalent in the adipose tissue of glucose-tolerant AG4OX mice, wh...
T84425 5-POHSA

Others Others
Branched fatty acid esters of hydroxy fatty acids (FAHFAs), endogenous lipids influenced by fasting and high-fat diets, are linked to improved insulin sensitivity in mice. These molecules consist of a C-16 or C-18 fatty acid (e.g., palmitoleic, palmitic, oleic, or stearic acid) bonded to a C-16 or C-18 hydroxy fatty acid. A specific FAHFA, 5-POHSA, features palmitoleic acid esterified with hydroxy stearic acid at the 5th carbon. Elevated levels of 5-POHSA in the serum of AG4OX mice, which expres...
T84429 12-POHSA

Others Others
Branched fatty acid esters of hydroxy fatty acids (FAHFAs) have emerged as significant regulators of metabolic processes, influenced by dietary changes such as fasting and high-fat diets, and are linked to improved insulin sensitivity in mice. These compounds typically feature a fatty acid chain, either C-16 or C-18 in length (for example, palmitoleic, palmitic, oleic, or stearic acid), esterified to a hydroxy fatty acid of similar length. A specific FAHFA, 12-POHSA, involves the esterification ...
T36586 12-PAHSA

Others Others
Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are newly identified endogenous lipids regulated by fasting and high-fat feeding and associated with insulin sensitivity. Structurally, these esters are comprised of a C-16 or C-18 fatty acid (e.g., palmitoleic, palmitic, oleic, or stearic acid) linked to either a C-16 or C-18 hydroxy substituent. 12-PAHSA is a FAHFA in which palmitic acid is esterified at the 12th carbon of hydroxy stearic acid. Among the FAHFA family members, PAHSAs ar...
T35800 MD001

Others Others
MD001 is a dual agonist of peroxisome proliferator-activated receptor α (PPARα) and PPARγ.1 It binds to PPARα and PPARγ (Kds = 9.55 and 0.14 μM, respectively) but does not bind to PPARβ/δ at concentrations up to 500 μM. It increases transcriptional activity of PPARα and PPARγ in a cell-based luciferase reporter assay when used at a concentration of 10 μM. MD001 (10 μM) increases expression of PPARα, PPARγ, and retinoid X receptor (RXR), as well as PPARα and PPARγ target genes, in HepG2 cells. It...
T36590 9-PAHSA

Others Others
Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are newly identified endogenous lipids regulated by fasting and high-fat feeding and associated with insulin sensitivity. Structurally, these esters are comprised of a C-16 or C-18 fatty acid (e.g., palmitoleic, palmitic, oleic, or stearic acid) linked to a hydroxylated C-16 or C-18 lipid. 9-PAHSA is a FAHFA in which palmitic acid is esterified to 9-hydroxy stearic acid. PAHSAs are the most abundant forms of FAHFA in serum as well as whi...
T84428 9-POHSA

Others Others
Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are recent discoveries in endogenous lipids that are influenced by dietary changes such as fasting and high-fat diets, showing a link with enhanced insulin sensitivity in mice. These compounds typically feature a C-16 or C-18 fatty acid (e.g., palmitoleic, palmitic, oleic, or stearic acid) bound to a hydroxy group on another C-16 or C-18 fatty chain. A specific FAHFA, 9-POHSA, consists of palmitoleic acid connected at the hydroxy stearic...
T84415 9-PAHSA 13C4

Others Others
Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are a class of endogenous lipids whose levels are modulated by fasting and high-fat diets, and they play a role in insulin sensitivity. These compounds consist of a fatty acid—either a C-16 or C-18, such as palmitoleic, palmitic, oleic, or stearic acid—esterified to a hydroxylated C-16 or C-18 lipid. One notable FAHFA, 9-PAHSA, features an ester linkage between palmitic acid and 9-hydroxy stearic acid. PAHSAs, with 9-PAHSA being the most...

化合物

GLUT4-IN-2
Cat.No: T61695
Synonym:
Target: transporter
GLUT4 activator 1
Cat.No: T11420
Synonym:
Target: Others
KL-11743
Cat.No: T9558
Synonym:
Target: transporter
M617 acetate
Cat.No: TP1993L
Synonym:
Target: Neuropeptide Y Receptor
MitoPQ
Cat.No: T33412
Synonym: MitoParaquat
Target: Glucokinase, transporter
BAY-876
Cat.No: T3713
Synonym:
Target: transporter
Fasentin
Cat.No: T8616
Synonym: N-[4-chloro-3-(trifluoromethyl)phenyl]-3-oxobutanamide
Target: transporter
MOTS-c(Human) Acetate(1627580-64-6 free)
Cat.No: TP2312
Synonym:
Target: Others, AMPK
CTPI-2
Cat.No: T8732
Synonym:
Target: Others, Mitochondrial Metabolism
M617 TFA
Cat.No: T75817
Synonym:
Target:
MOTS-c(human) acetate
Cat.No: T76039
Synonym:
Target:
13-OAHSA
Cat.No: T84422
Synonym:
Target: Others
10-PAHSA
Cat.No: T36142
Synonym:
Target: Others
5-SAHSA
Cat.No: T84424
Synonym:
Target: Others
Palmitoleic Acid sodium
Cat.No: T85300
Synonym: C16:1(9Z),cis-Palmitoleic Acid,(9Z)-Hexadecenoic Acid,C16:1 n-7
Target: Others
5-OAHSA
Cat.No: T84426
Synonym:
Target: Others
13-SAHSA
Cat.No: T84420
Synonym:
Target: Others
10-SAHSA
Cat.No: T84387
Synonym:
Target: Others
9-SAHSA
Cat.No: T84431
Synonym:
Target: Others
13-POHSA
Cat.No: T84421
Synonym:
Target: Others
12-OAHSA
Cat.No: T84430
Synonym:
Target: Others
10-OAHSA
Cat.No: T84386
Synonym:
Target: Others
12-SAHSA
Cat.No: T84432
Synonym:
Target: Others
9-OAHSA
Cat.No: T84427
Synonym:
Target: Others
13-PAHSA
Cat.No: T84407
Synonym:
Target: Others
5-POHSA
Cat.No: T84425
Synonym:
Target: Others
12-POHSA
Cat.No: T84429
Synonym:
Target: Others
12-PAHSA
Cat.No: T36586
Synonym:
Target: Others
MD001
Cat.No: T35800
Synonym:
Target: Others
9-PAHSA
Cat.No: T36590
Synonym:
Target: Others
9-POHSA
Cat.No: T84428
Synonym:
Target: Others
9-PAHSA 13C4
Cat.No: T84415
Synonym:
Target: Others
Cat. No. Product Name Target Signaling Pathways
T2S0820 Karanjin

干华豆晶 4,水黄皮素

Apoptosis; AMPK Apoptosis; Chromatin/Epigenetic; PI3K/Akt/mTOR signaling
Karanjin 是干花豆中的主要活性呋喃黄酮醇成分,可通过细胞周期阻滞诱导癌细胞死亡,促进细胞凋亡,还通过提高AMPK 的方式诱导骨骼肌细胞 GLUT4 易位。
T13475 β-Aminopropionitrile

3-氨基丙腈,3-Aminopropionitrile,BAPN

Others; Endogenous Metabolite Metabolism; Others
β-Aminopropionitrile (3-Aminopropionitrile) 是赖氨酰氧化酶的特异性抑制剂。
T8771 Pongamol

Others Others
Pongamol 是一种从 Pongamia pinnata 果实中鉴定出的铅分子,对骨骼肌细胞的葡萄糖摄取和 GLUT4 易位。
TN1100 Nepodin

transporter; COX; AMPK; Parasite Chromatin/Epigenetic; Immunology/Inflammation; Metabolism; Microbiology/Virology; Neuroscience; PI3K/Akt/mTOR signaling
Nepodin 是从Rumex crispus 中分离的一种醌氧化还原酶抑制剂,具有抗糖尿病和抗疟疾的作用。。它通过激活 AMPK 刺激 GLUT4 向质膜的转运。
T4S0295 Apigenin 7-glucoside

波斯菊,Cosmetin,Cosmosiin,Cosmosioside,Apigenin-7-O-β-D-glucopyranoside,芹甙元-7-葡萄糖苷,Thalictiin,Apigetrin

Reactive Oxygen Species; HIV Protease Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB; Proteases/Proteasome
Apigenin 7-glucoside (Cosmosiin) 是一种 ROS 清除剂,具有抗增殖、抗氧化作用。
T4S1545 Licarin B

(-)-Licarin B,Licarine B,(-)-利卡灵B

transporter; Antibacterial; PPAR DNA Damage/DNA Repair; Metabolism; Microbiology/Virology
Licarin B (Licarine B) 是来源于肉豆蔻种子的一种天然产物,是 NO 生成抑制剂,可通过激活 IRS-1/PI3K/AKT 通路中的PPARγ和GLUT4 改善胰岛素敏感性。
T2755 Rhoifolin

野漆树苷,Apigenin-7-O-rhamnoglucoside,Apigenin 7-O-neohesperidoside,Rhoifoloside

Others; p38 MAPK; NF-κB; transporter; IGF-1R; Autophagy Autophagy; MAPK; Metabolism; NF-κB; Others; Tyrosine Kinase/Adaptors
Rhoifolin (Apigenin 7-O-neohesperidoside) 是从琯溪蜜柚叶子分离的一种黄酮糖苷。它通过 RANKL 诱导的NF-κB 和MAPK 途径改善钛颗粒刺激的骨溶解并减少破骨细胞生成。它通过增强脂联素分泌,胰岛素受体-β的酪氨酸磷酸化和GLUT4易位有助于治疗糖尿病并发症。
TMA0127 Ficusin A

transporter; PPAR DNA Damage/DNA Repair; Metabolism
Ficusin has antioxidant, antilipidemic and antidiabetic effects, it can lower the levels of fasting blood glucose, plasma insulin, body weight gain in HFD-STZ induced diabetic rats, and can significantly enhance the PPARγ expression and improve the transl
TN3882 Dodoviscin A

cAMP; Tyrosinase; transporter GPCR/G Protein; Metabolism; Proteases/Proteasome
Dodoviscin A may be a new promising pigmentation-altering agent for cosmetic and therapeutic applications, it can inhibit melanin biosynthesis induced by 3-isobutyl-1-methylxanthine and PD98059.Dodoviscin A can promote adipocyte differentiation as charact

天然产物

Karanjin
Cat.No: T2S0820
Synonym: 干华豆晶 4,水黄皮素
Target: Apoptosis, AMPK
β-Aminopropionitrile
Cat.No: T13475
Synonym: 3-氨基丙腈,3-Aminopropionitrile,BAPN
Target: Others, Endogenous Metabolite
Pongamol
Cat.No: T8771
Synonym:
Target: Others
Nepodin
Cat.No: TN1100
Synonym:
Target: transporter, COX, AMPK, Parasite
Apigenin 7-glucoside
Cat.No: T4S0295
Synonym: 波斯菊,Cosmetin,Cosmosiin,Cosmosioside,Apigenin-7-O-β-D-glucopyranoside,芹甙元-7-葡萄糖苷,Thalictiin,Apigetrin
Target: Reactive Oxygen Species, HIV Protease
Licarin B
Cat.No: T4S1545
Synonym: (-)-Licarin B,Licarine B,(-)-利卡灵B
Target: transporter, Antibacterial, PPAR
Rhoifolin
Cat.No: T2755
Synonym: 野漆树苷,Apigenin-7-O-rhamnoglucoside,Apigenin 7-O-neohesperidoside,Rhoifoloside
Target: Others, p38 MAPK, NF-κB, transporter, IGF-1R, Autophagy
Ficusin A
Cat.No: TMA0127
Synonym:
Target: transporter, PPAR
Dodoviscin A
Cat.No: TN3882
Synonym:
Target: cAMP, Tyrosinase, transporter
Cat. No. Product Name Species Expression System
TMPY-01960 Munc18c/STXBP3 Protein, Human, Recombinant (His & GST)

syntaxin binding protein 3,MUNC18C,UNC-18C,MUNC18-3,PSP

Human Baculovirus Insect Cells
Syntaxin-binding protein 3, also known as Platelet Sec1 protein, Protein unc-18 homolog 3, Protein unc-18 homolog C, Unc-18C, Unc18-3 and STXBP3, is a cytoplasm protein which belongs to the STXBP/unc-18/SEC1 family. STXBP3 is expressed in cells that exhibit granule exocytosis, such as neutrophils, mast cells, platelets and endothelial cells. STXBP3, together with STX4 and VAMP2, may play a role in insulin-dependent movement of GLUT4 and in docking / fusion of intracellular GLUT4-containing vesic...
TMPH-02873 RAB10 Protein, Mouse, Recombinant (His & SUMO)

Ras-related protein Rab-10,Rab10

Mouse E. coli
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is mainly involved in the biosynthetic transport of proteins from the Golgi to the plasma membrane. Regulates, f...

重组蛋白

Munc18c/STXBP3 Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-01960
Species: Human
Expression System: Baculovirus Insect Cells
RAB10 Protein, Mouse, Recombinant (His & SUMO)
Cat.No: TMPH-02873
Species: Mouse
Expression System: E. coli
Cat. No. Product Name Target Signaling Pathways
T71981 Gliclazide-d4

Gliclazide-d4 is intended for use as an internal standard for the quantification of gliclazide by GC- or LC-MS. Gliclazide is a sulfonylurea and an inhibitor of pancreatic β-cell ATP-sensitive potassium (KATP) channels. It is selective for pancreatic β-cell over cardiac and arterial smooth muscle cell KATP channels. Gliclazide (5 μM) increases insulin-induced glucose uptake and glucose transporter 4 (GLUT4) translocation to the plasma membrane in a differentiated 3T3L1 adipocyte model of insulin...

同位素标记化合物

Gliclazide-d4
Cat.No: T71981
Synonym:
Target:
TargetMol Loading
联系我们
400-820-0310

上海市静安区江场三路238号8楼