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血小板源生长因子受体 (Platelet-Derived Growth Factor Receptors, PDGFRs)

血小板源生长因子受体 (Platelet-Derived Growth Factor Receptors, PDGFRs) 是血小板源生长因子(PDGF)家族成员的细胞表面酪氨酸激酶受体。PDGF亚基-A和-B是调节细胞增殖、细胞分化、细胞生长、发育和包括癌症在内的许多疾病的重要因素。PDGF-R有两种形式,α和β,每种形式由不同的基因编码。根据结合的生长因子,PDGF-R 同源或异源二聚化。对 RTKs 诱导的不同信号级联的检查确立了 Ras/MAPK、PI3K和PLCγ通路作为 PDGFR 信号转导的关键下游介质。此外,活性氧依赖性 STAT3 激活已被确定为血管平滑肌细胞中 PDGFR 信号传导的关键下游介质。

  • PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated
    TMPK-00420
    Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. There are four members of PDGF family known as PDGF-A chain, PDGF-B chain, PDGF-C chain and PDGF-D chain, which in active forms are dimers. As far as two receptors PDGF-alpha R and PDGF-beta R are known to bind PDGF. PDGF R alpha PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 59.2 kDa and the accession number is P16234.
    • ¥ 5180
    5日内发货
    规格
    数量
  • PDGF R alpha/PDGFRA Protein, Cynomolgus, Recombinant (His)
    TMPK-00943
    Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. There are four members of PDGF family known as PDGF-A chain, PDGF-B chain, PDGF-C chain and PDGF-D chain, which in active forms are dimers. As far as two receptors PDGF-alpha R and PDGF-beta R are known to bind PDGF. PDGF R alpha PDGFRA Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 57.32 kDa and the accession number is Q0PW86.
    • ¥ 3100
    5日内发货
    规格
    数量
  • PDGF R beta/CD140b Protein, Canine, Recombinant (His)
    TMPK-01050
    PDGF R beta CD140b Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 57.25 kDa and the accession number is Q6QNF3.
    • ¥ 3100
    5日内发货
    规格
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  • PDGFRA Protein, Human, Recombinant (His)
    TMPY-01139
    PDGFRA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.7 kDa and the accession number is P16234-1.
    • ¥ 3820
    现货
    规格
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  • PDGFRB Protein, Rat, Recombinant (His)
    TMPY-03140
    PDGFRB Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.6 kDa and the accession number is Q05030.
    • ¥ 2530
    5日内发货
    规格
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  • PDGFRA Protein, Mouse, Recombinant (hFc)
    TMPY-05789
    PDGFRA Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 83.15 kDa and the accession number is P26618-2.
    • ¥ 2270
    5日内发货
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  • PDGFRA Protein, Mouse, Recombinant (His)
    TMPY-05787
    PDGFRA Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.87 kDa and the accession number is P26618-2.
    • ¥ 2270
    5日内发货
    规格
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  • PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi)
    TMPK-00419
    Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. There are four members of PDGF family known as PDGF-A chain, PDGF-B chain, PDGF-C chain and PDGF-D chain, which in active forms are dimers. As far as two receptors PDGF-alpha R and PDGF-beta R are known to bind PDGF. PDGF R alpha PDGFRA Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 59.2 kDa and the accession number is P16234.
    • ¥ 1840
    5日内发货
    规格
    数量
  • PDGF R beta/CD140b Protein, Cynomolgus, Recombinant (His)
    TMPK-00481
    Platelet-derived growth factor receptor (PDGFR) signaling is involved in proliferation and survival in a wide array of cell types.PDGFR-β signalling, via TGF-β signalling, may be crucial for restoration of BBB integrity after cerebral ischemia and therefore represents a novel potential therapeutic target.
    • ¥ 2960
    5日内发货
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  • PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi)
    TMPK-00421
    PDGF R beta CD140b Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 59 kDa and the accession number is P09619.
    • ¥ 2210
    5日内发货
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  • PDGFRB Protein, Rhesus, Recombinant (hFc)
    TMPY-00385
    PDGFRB Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 83.3 kDa and the accession number is F7BTH1.
    • ¥ 3170
    5日内发货
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  • PDGFRB Protein, Human, Recombinant
    TMPY-05358
    PDGFRB Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 56.2 kDa and the accession number is P09619-1.
    • ¥ 3170
    5日内发货
    规格
    数量
  • PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi), Biotinylated
    TMPK-00422
    PDGF R beta CD140b Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 59 kDa and the accession number is P09619.
    • ¥ 5180
    5日内发货
    规格
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  • PDGFRB Protein, Rhesus, Recombinant (His)
    TMPY-03590
    PDGFRB Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.7 kDa and the accession number is F7BTH1.
    • ¥ 3170
    5日内发货
    规格
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  • PDGFRB Protein, Human, Recombinant (His), Biotinylated
    TMPY-04937
    PDGFRB Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.6 kDa and the accession number is P09619-1.
    • ¥ 1950
    5日内发货
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  • PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated
    TMPY-05608
    PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 59.4 kDa and the accession number is P16234-1.
    • ¥ 2940
    5日内发货
    规格
    数量
  • PDGFRB Protein, Human, Recombinant (His)
    TMPY-01207
    PDGFRB Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.6 kDa and the accession number is P09619-1.
    • ¥ 3170
    5日内发货
    规格
    数量
  • PDGFRA Protein, Human, Recombinant (hFc)
    TMPY-00900
    PDGFRA Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 82.9 kDa and the accession number is P16234-1.
    • ¥ 3820
    5日内发货
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  • PDGFRA Protein, Rat, Recombinant (hFc)
    TMPY-03919
    PDGFRA Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 83.2 kDa and the accession number is G3V6A0.
    • ¥ 4460
    5日内发货
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  • PDGFRB Protein, Rat, Recombinant (hFc)
    TMPY-03474
    PDGFRB Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 83.2 kDa and the accession number is Q05030.
    • ¥ 3170
    5日内发货
    规格
    数量
  • PDGFRB Protein, Human, Recombinant (hFc)
    TMPY-05497
    PDGFRB Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 82.8 kDa and the accession number is P09619-1.
    • ¥ 2530
    5日内发货
    规格
    数量
  • PDGFRA Protein, Rat, Recombinant (His)
    TMPY-03825
    PDGFRA Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.6 kDa and the accession number is A6JD04.
    • ¥ 4460
    5日内发货
    规格
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  • PDGFRA Protein, Cynomolgus, Recombinant (His)
    TMPY-06921
    PDGFRA Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.68 kDa and the accession number is Q0PW86.
    • ¥ 3820
    5日内发货
    规格
    数量