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Cat. No. | Product Name | ||
---|---|---|---|
L6810 | 中药单体化合物库 | 2755 compounds | |
2755 种中药来源的单体化合物,是药物开发、药理研究等领域的有力工具; | |||
L6800 | 中国药典收录天然产物库 | 2051 compounds | |
2051 种中国药典收录的天然产物,是药物开发、药理研究等领域的有力工具; |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T34720 |
Stichoposide
Stichoposide A,Holotoxins |
Others | Others |
Stichoposide is a triterpene glycoside. | |||
T32093 |
Holothurin A
|
Others | Others |
Holothurin A is a triterpene glycoside. | |||
T32662 |
Leucasin
|
Others | Others |
Leucasin is a triterpene saponin from Leucas nutans. | |||
T32554 |
Lancilactone A
|
Others | Others |
Lancilactone A is a triterpene lactone. | |||
T25612 |
Lanatoside E
4-18-00-02468 (Beilstein Handbook Reference) |
Others | Others |
Lanatoside E is a cyclic triterpene saponin with antitumor activity. | |||
TP2441 |
Stichloroside B1
|
||
Stichloroside B1 is a triterpene saponin. | |||
T33884 |
Parkeol
|
Others | Others |
Parkeol is the triterpene precursor of saponins in sea cucmbers. | |||
TP2425 |
Cucumarioside A6-2
|
||
Cucumarioside A6-2 is a triterpene glycoside. | |||
TP2433 |
Pervicoside B
Neothyoside C |
||
Pervicoside B is a triterpene glycoside. | |||
TP2427 |
Cucumarioside G1
|
||
Cucumarioside G1 is a triterpene glycoside of holothurian from Cucumaria fraudatrix. | |||
T32747 |
Licorice saponin C2
Saponin C2, from licorice,Licoricesaponin C2 |
Others | Others |
Licorice saponin C2 is an oleanane-type triterpene oligoglycoside extracted from the air-dried root of Glycyrrhiza uralensis. | |||
TP2442 |
Stichloroside C2
|
||
Stichloroside C2 is a triterpene saponin from the sea cucumber Stichopus chloronotus. | |||
T34511 |
Sandosaponin B
|
Others | Others |
Sandosaponin B is a olean-12-ene-type triterpene oligoglycoside isolated from kidney bean, the seed of Phaseolus vulgaris L. | |||
T33215 |
Masticadienediol
|
Others | Others |
Masticadienediol is a tetracyclic triterpene. | |||
T25278 |
Cucumarioside A2-2
|
Others | Others |
Cucumarioside A2-2 is a triterpene glycoside isolated from the Far-Eastern sea cucumber Cucumaria japonica, that exhibits antitumor activity. | |||
TP2443 |
Thelenotoside B
|
||
Thelenotoside B is a triterpene tetraglycoside. | |||
TP2428 |
Cucumarioside H
|
||
Cucumarioside H is a triterpene glycoside | |||
T38088 |
28-Deoxybetulin methyleneamine
|
Others | Others |
28-Deoxybetulin methyleneamine is a pentacyclic triterpenoid and derivative of the cholesterol biosynthesis inhibitor betulin .1It has been used in the synthesis of triterpene derivatives with antiviral activity. 1.Nitz, T.J., Montalbetti, C., Mears, R., et al.Extended Triterpene Derivatives(2008) | |||
T20836 |
Sandosaponin A
|
Others | Others |
Sandosaponin A, an olean-12-ene-type triterpene oligoglycoside, is isolated from kidney bean, the seed of Phaseolus vulgaris L. | |||
T37038 |
Betulinic Acid propargyl ester
|
Others | Others |
Betulinic acid propargyl ester is a pentacyclic lupane triterpene and alkyne derivative of betulinic acid .1,2It has been used in click chemistry reactions for the synthesis of cytotoxic anticancer betulinic acid derivatives. | |||
T35678 |
2,3-Indolobetulinic glycine amide
|
Others | Others |
2,3-Indolobetulinic glycine amide is a pentacyclic triterpene and derivative of betulinic acid .1It has been used in the synthesis of betulinic acid derivatives with anticancer activity. 1.Kumar, V., Rani, N., Aggarwal, P., et al.Synthesis and cytotoxic activity of heterocyclic ring-substituted betulinic acid derivativesBioorg. Med. Chem. Lett.18(18)5058-5062(2008) | |||
T35760 |
Carnaubadiol
|
Others | Others |
Carnaubadiol is a triterpene that has been found in E. corollata and has antiprotozoal activities.1,2 It is active against L. infantum promastigotes and amastigotes, as well as T. cruzi trypomastigotes (IC50s = 46.2, 7.8, and 14.9 μM, respectively).2 |1. Piatak, D.M., and Reimann, K.A. Plant investigations IV. Corollatadiol A new triterpene from euphorbia corollata. Tetrahedron Lett. 13(44), 4525-4528 (1972).|2. de Almeida, B.C., Araújo, B.Q., Carvalho, A.A., et al. Antiprotozoal activity of ext... | |||
T36412 |
Multiflorenol
|
Others | Others |
Multiflorenol is a triterpene that has been found in T. kirilowii seeds.1 It inhibits in vitro activation of Epstein-Barr virus early antigen (EBV-EA) induced by the tumor promoter phorbol 12-myristate 13-acetate in a concentration-dependent manner. |1. Akihisa, T., Tokuda, H., Ichiishi, E., et al. Anti-tumor promoting effects of multiflorane-type triterpenoids and cytotoxic activity of karounidiol against human cancer cell lines. Cancer Lett. 173(1), 9-14 (2001). | |||
T35686 |
3-Acetyl Betulinaldehyde
|
Others | Others |
3-Acetyl betulinaldehyde is a triterpene and derivative of the cholesterol biosynthesis inhibitor betulin that has been found inA. japonica.1It is an intermediate in the synthesis of 3-acetylbetulinic acid, as well as various lupine and germanicane triterpenes and saponins with anticancer activity.2 1.Tung, N.H., Kwon, H.-J., Kim, J.-H., et al.An anti-influenza component of the bark of Alnus japonicaArch. Pharm. Res.33(3)363-367(2010) 2.Thibeault, D., Gauthier, C., Legault, J., et al.Synthesis a... | |||
T63092 |
Anti-inflammatory agent 12
|
Others | Others |
Anti-inflammatory agent 12 是一种五环三萜化合物,在 LPS 诱导的炎症反应中表现出显着的偏差 (IC50: 2.22 μM)。Anti-inflammatory agent 12 具有潜力用于炎症性疾病的研究。 | |||
T63061 |
Anti-inflammatory agent 13
|
Others | Others |
Anti-inflammatory agent 13 是一种五环三萜化合物,对炎症模型具有明显的抑制作用。Anti-inflammatory agent 13 具有潜力进行 DAMP 或 PAMP 引发炎症的研究。 | |||
T69215 |
Ambrein
|
Others | Others |
Ambrein is a triterpene alcohol that is the chief constituent of ambergris, a secretion from the digestive system of the sperm whale, and has been suggested as the possible active component producing the supposed aphrodisiac effects of ambergris. It serves as the biological precursor for a number of aromatic derivatives such as ambroxan and is thought to possess fixative properties for other odorants. It has been shown to act as an analgesic and it has been proven to increase sexual behavior in ... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TP2223 |
Beesioside Q
|
Others | Others |
Beesioside Q 是从铁破锣 Beesia calthaefolia (Maxim.) Ulbr 的根茎中提取出来的天然产物。 | |||
TN1006 |
Tirucallol
|
NOS; NO Synthase; Prostaglandin Receptor | GPCR/G Protein; Immunology/Inflammation |
Tirucallol 是一种四环三萜,分离自Euphorbia lacteal 乳胶。它能够抑制小鼠模型中的耳部水肿,并阻碍脂多糖刺激的巨噬细胞中亚硝酸盐的产生,具有局部消炎作用。 | |||
T3769 |
Tenuifolin
|
Others; Beta-Secretase; AChE | Neuroscience; Others |
Tenuifolin 是一种从远志中分离出的三萜,能够抑制β-secretase 以减少 Aβ 蛋白分泌,具有神经保护作用。 它可通过降低 AChE 活性来改善衰老小鼠的学习和记忆能力,有潜力用于阿尔茨海默氏病的研究。 | |||
TN2097 |
Pomolic acid
坡模酸 |
Apoptosis; Caspase; HIV Protease; AMPK | Apoptosis; Chromatin/Epigenetic; Microbiology/Virology; PI3K/Akt/mTOR signaling; Proteases/Proteasome |
Pomolic acid 是从野鸦椿中分离出来的一种五环三萜烯。它抑制肿瘤细胞的生长,诱导细胞凋亡,有用于前列腺癌的潜力。 | |||
TQ0248 |
Alisol F
泽泻醇 F,泽泻醇F |
HBV | Microbiology/Virology |
Alisol F 是从泽泻中分离得到的一种三萜,具有免疫抑制和抗病毒功能。 | |||
TN2341 |
Cucurbitacin Q1
葫芦素F-25-乙酸酯,葫芦素Q1 |
Others | Others |
Cucurbitacin Q1 是一种天然的四环三萜,来源于Cucumis prophetarum。 | |||
TN2289 |
Licorice-saponin H2
18Β,20Α-甘草酸,Licoricesaponin H2 |
Others | Others |
Licorice-saponin H2 (Licoricesaponin H2) 是一种从甘草中获得的皂苷。 | |||
T5S0018 |
Betulonic acid
路路通酸,(+)-Betulonic acid,Betunolic acid,Liquidambaric acid |
Parasite; HSV | Microbiology/Virology |
Betulonic acid (Liquidambaric acid) 是一种在许多植物中存在的三萜类天然产物,具有抗肿瘤,抗炎,抗寄生虫和抗病毒的活性。 | |||
TN6909 |
Polyporusterone B
猪苓酮B,(1R,2R,4S,5R,7R,11R,14S,15R)-14-[(2R,3R)-2,3-dihydroxy-6-methyl-5-methylideneheptan-2-yl]-4,5,11-trihydroxy-2,15-dimethyltetracyclo[8.7.0.02,?.011,1?]heptadec-9-en-8-one |
Others | Others |
Polyporusterone B ((1R,2R,4S,5R,7R,11R,14S,15R)-14-[(2R,3R)-2,3-dihydroxy-6-methyl-5-methylideneheptan-2-yl]-4,5,11-trihydroxy-2,15-dimethyltetracyclo[8.7.0.02,?.011,1?]heptadec-9-en-8-one) 是一种三萜羧酸,从Polyporus umbellatusFries 中分离得到。它对自由基诱导的红细胞裂解 (溶血) 具有抑制作用。 | |||
T2S0618 |
β-Elemonic Acid
3-oxo Tirucallic Acid,β-岚香酮酸,Beta-Elemonic acid,3-Oxotirucallenoic Acid,β-榄香酮酸,Elemadienonic Acid |
Apoptosis; Reactive Oxygen Species; COX | Apoptosis; Immunology/Inflammation; Metabolism; Neuroscience; NF-κB |
β-Elemonic Acid (3-Oxotirucallenoic Acid) 是从乳香树中分离得到的一种三萜,具有抗癌和抗炎作用。它抑制脯氨酰内肽酶,诱导细胞凋亡,活性氧和COX-2表达。 | |||
TN1402 |
Arjungenin
阿江榄仁素,2ALPHA,19ALPHA,23-三羟基齐墩果酸 |
Antifection; Immunology/Inflammation related | Immunology/Inflammation; Microbiology/Virology |
Arjungenin, a triterpene derived from Terminalia arjuna, exhibits insect feeding-deterrent and growth inhibitory properties. | |||
T11364 |
Ganoderic acid TR
|
Antiviral; Influenza Virus | Immunology/Inflammation; Microbiology/Virology |
Ganoderic acid TR 是一种从药用灵芝中分离出口来的三萜化合物,是 H5N1 和 H1N1 NAs 抑制剂,具有广谱的抗病毒活性。 | |||
TN1457 |
Bryonamide B
|
||
Bryonamide B 是一种可从 Bryonia aspera 中提取得到一种葫芦类三萜。 | |||
T2813 |
Madecassoside
Asiaticoside A,羟基积雪草苷 |
Apoptosis; Antioxidant; Endogenous Metabolite | Apoptosis; Metabolism; oxidation-reduction |
Madecassoside (Asiaticoside A) 是从崩大碗中分离出来的一种五环三萜,有抗炎症,抗氧化和抗衰老的作用。 | |||
T5S1028 |
3,29-Dibenzoyl Rarounitriol
|
Others | Others |
3,29-Dibenzoyl rarounitriol 是Trichosanthes kirilowii中多氯烷三萜酯的主要活性化合物,能够用作Trichosanthes kirilowii定量标记物。 | |||
T10689 |
Cauloside D
|
Others | Others |
Cauloside D 是一种分离自 Caulophyllum robustumMax 中的三萜苷类化合物。它能够阻碍 iNOS 和促炎细胞因子的表达,具有抗炎活性。 | |||
TN7228 |
11-oxo-alpha-amyrin
Neoilexonol |
||
11-oxo-alpha-amyrin (Neoilexonol) 是一种从Leonurus japonicus (Lamiaceae) 提取出的三萜化合物,是一种天然化合物 。 | |||
TN6737 |
(25R)-Spirost-4-ene-3,12-dione
|
Others | Others |
(25R)-Spirost-4-ene-3,12-dione 是一种天然产物,抑制中性粒细胞超氧阴离子的产生和肥大细胞组胺的释放。 | |||
TN1111 |
Arnidiol
|
Immunology/Inflammation related | Immunology/Inflammation |
Arnidiol 是一种五环三萜烯,从Barleria Longiflora LinnF. 中提取得到。 | |||
TN1937 |
Mogroside IV-A
罗汉果皂苷IVA |
Others; Antioxidant | Others; oxidation-reduction |
Mogroside IVa 是一种从罗汉果提取物中分离出来的三萜糖苷。它是一种非糖类甜味剂。Mogroside 比蔗糖更甜,具有抗氧化,抗糖尿病和抗癌作用。 | |||
T2777 |
Ginsenoside Rg1
Sanchinoside C1,Panaxoside Rg1,Sanchinoside Rg1,人参皂苷Rg1,Panaxoside A,人参皂苷 Rg1,Ginsenoside A2 |
Apoptosis; Beta Amyloid; NF-κB | Apoptosis; Neuroscience; NF-κB |
Ginsenoside Rg1 (Panaxoside Rg1) 是人参的主要活性成分之一,可减少NF-κB 核易位。它改善认知功能受损,通过降低大脑Aβ水平来发挥作用。 | |||
TMS0879 |
Asiaticoside B
积雪草苷 B,积雪草苷B |
Others | Others |
Asiaticoside B 是一种从类叶升麻中分离得到的三萜糖苷,具有抗肿瘤作用。 它对 HepG2 和 MCF-7 癌细胞系具有显著的细胞毒性。 | |||
TN6908 |
Polyporusterone A
(1R,2R,4S,5R,7R,11R,14S,15R)-14-[(2R,3R,5S)-2,3-dihydroxy-5,6-dimethylheptan-2-yl]-4,5,11-trihydroxy-2,15-dimethyltetracyclo[8.7.0.02,?.011,1?]heptadec-9-en-8-one |
||
Polyporusterone A 是一种从 P. umbellatus 的子实体中提取出来的三萜羧酸。Polyporusterone A 抑制自由基诱导的红细胞裂解 (溶血) ,可用于研究头发再生和牛皮癣。 | |||
TN7227 |
3β-Acetoxyurs-12-en-11-one
11-Ketoamyrinacetate |
Antibacterial; Antibiotic; Antifungal | Microbiology/Virology |
3β-Acetoxyurs-12-en-11-one (11-Ketoamyrinacetate) 是一种从 Morus mesozygia 的茎皮和 Ficus hirta Vahl (桑科) 的叶中发现的熊烷三萜类天然产物。 | |||
T5737 |
euphol
|
Others; Lipase; Endogenous Metabolite | Metabolism; Others |
Euphol 是从Euphorbia tirucalli 的汁液中分离出来的四环三萜醇,具有抗炎和免疫调节作用,口服具有活力。 它通过能够逆机制抑制单酰基甘油脂肪酶 (MGL) 的特性,IC50=315 nM。 外周 MGL 抑制能够调节内源性大麻素系统从而阻止炎症性疼痛的发展。 | |||
T16324 |
Nimbolide
|
Apoptosis; NF-κB; CDK | Apoptosis; Cell Cycle/Checkpoint; NF-κB |
Nimbolide 是源自印楝叶和花的一种三萜。它抑制CDK4/CDK6激酶活性。它抑制 NF-κB,Wnt,PI3K-Akt,MAPK 和 JAK-STAT 信号通路。它通过抑制NF-κB 而诱导肿瘤细胞凋亡。 | |||
T3121 |
Betulin
Trochol,betulinic alcohol,betuline,betulinol,桦木醇,Betulol,白桦脂醇 |
Apoptosis; Endogenous Metabolite; Lipid; Fatty Acid Synthase | Apoptosis; Metabolism |
Betulin (betulinol) 是从桦树树皮中分离出来的一种天然三萜,是 SREBP 抑制剂。 | |||
T6654 |
Saponins
Sapogenins Glycosides,皂素,Saponin |
Others | Others |
Saponins (Sapogenins Glycosides) 是一种苷类的化合物,多发现于多种植物中,可保护植物免受微生物和真菌的破坏。 | |||
T2830 |
Betulinic acid
白桦脂酸,桦木酸,ALS-357,Lupatic acid,Betulic acid |
Apoptosis; Mitophagy; NF-κB; HIV Protease; Topoisomerase; Endogenous Metabolite; Aminopeptidase; Autophagy | Apoptosis; Autophagy; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology; NF-κB; Proteases/Proteasome |
Betulinic acid (ALS-357) 是从白桦树皮中分离出来的一种五环三萜类天然产物,是真核细胞拓扑异构酶 I 的抑制剂,IC50值为 5 μM,具有抗逆转录病毒、抗疟疾、抗癌和抗炎特性。 | |||
T4S1383 |
Escin IA
Aescin IA,Escin IA;Aescin IA,Escin IA |
HIV Protease | Microbiology/Virology; Proteases/Proteasome |
Escin IA (Escin IA;Aescin IA);Aescin IA 是从马蹄中七叶树分离出的一种三萜皂苷,抑制HIV-1蛋白酶,IC50值为 35 μM。它具有抗 TNBC 转移活性,其作用机制涉及通过下调 LOXL2 表达抑制上皮-间质转化过程。 | |||
T31910 |
Ganoderiol A
(+)-Ganoderiol A |
||
Ganoderiol A is a tetracyclic triterpene extracted from Ganoderma amboinense. | |||
T11848 |
Licorice glycoside C2
甘草苷 C2 |
Others | Others |
Licorice glycoside C2 is a oleanane-type triterpene oligoglycoside isolated from Glycyrrhiza uralensis. | |||
T24884 |
Tingenone
Maytenin,Maitenin,Tingenin A,Tingenon |
||
Tingenone is a pentacyclic triterpene. It induces peripheral antinociception due to opioidergic activation. | |||
T13699 |
Gardenoin J
|
Others | Others |
Gardenoin J, a cycloartane triterpene derived from the exudate of Gardenia thailandica, is isolated. | |||
T34634 |
Shionoside C
|
||
Shionoside C, as a new oleanane-type triterpene glycoside, is obtained from the roots of Aster tataricus. | |||
T30096 |
Apioglycyrrhizin
|
||
Apioglycyrrhizin is a sweet oleanane-type triterpene oligoglycoside; isolated from the roots of Glycyrrhiza inflata. | |||
T12975 |
Sootepin D
|
NF-κB | NF-κB |
Sootepin D is a triterpene from the apical bud of Gardenia sootepensis, and is TNF-α-induced NF-κB inhibitor(IC50 of 8.3μM),with anti-inflammatory activity. | |||
TN3346 |
Actinidic acid
|
Others | Others |
Actinidic acid is a triterpene phytoalexin from unripe kiwi fruit. | |||
T10043 |
11-Oxomogroside IIe
|
Others | Others |
11-Oxomogroside IIe is a triterpene glycoside isolated from Siraitia grosvenori[1]. | |||
T83543 |
(E)-Masticadienonic acid
|
||
(E)-Masticadienonic acid为三萜类化合物,可从Vallesia glabra中提取。 | |||
T41137 |
Prosaikogenin A
|
Others | Others |
Prosaikogenin A, a triterpene saponin extracted from Clinopodium chinense, exhibits notable platelet aggregation promotion activity, indicated by an EC 50 value of 12.2 μM. | |||
T39570 |
Cycloartenyl ferulate
Cycloartenolferulate,Cycloartenolferulicacidester,环木菠萝烯醇阿魏酸酯 |
Others | Others |
Cycloartenyl ferulate (also known as cycloartenol ferulate) is a representative triterpene alcohol with diverse biological properties, such as antioxidant, anti-allergic, anti-inflammatory, and anticancer activities. | |||
T83397 |
23-Epi-26-deoxycimicifugoside
|
||
23-Epi-26-deoxycimicifugoside是源自Cimicifuga racemosa的一种三萜木糖。 | |||
T38777 |
Ilexoside O
|
Others | Others |
Ilexoside O, a triterpene saponin derived from Ilex pubescens roots, demonstrates modest inhibition of xanthine oxidase (XOD) activity with an IC50 value of 53.05 μM. | |||
T81419 |
Poricoic acid H
|
||
Poricoic acid H为三萜类化合物,具备独特的化学结构和生物活性。 | |||
T13964 |
Waltonitone
|
Others | Others |
Waltonitone is a natural ursane-type pentacyclic triterpene isolated from Gentian waltonii Burkill. | |||
T38805 |
Euphol acetate
|
Others | Others |
Euphol acetate, a triterpene found in Euphorbia broteri, has demonstrated inhibitory effects on the hepatic transport proteins known as organic anion-transporting polypeptide 1/3 (OATP1B1/3). | |||
T83396 |
23-Nor-6-oxopristimerol
|
||
23-Nor-6-oxopristimerol 为酚类二萜三萜化合物。 | |||
T83361 |
3-epi-Digitoxigenin
|
||
3-epi-Digitoxigenin为三萜类化合物,源自鸡蛋花叶及茎部的提取物。 | |||
T38928 |
Oleanolic acid-3-O-glucosyl(1-2)xylyl(1-3)glucosiduronic acid
|
Others | Others |
Oleanolic acid-3-O-glucosyl(1-2)xylyl(1-3)glucosiduronic acid is a naturally occurring triterpene saponin. | |||
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