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Targets Recommended: Others

13

抑制剂 & 化合物

6

天然产物

1

同位素标记化合物

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Cat. No. Product Name Target Signaling Pathways
T19567 Substituted piperidines-1

Others Others
Substituted piperidines-1 can promote the release of growth hormone in humans and animals.
T85308 Vitamin B3-d4

Nicotinic acid-(ring-d4),Nicotinic acid-d4

Autophagy Autophagy
Vitamin B3-d4 (Nicotinic acid-(ring-d4)) 是 Niacin 的氘代物,可用于跟踪 Niacin 在体内的代谢。
T20721 Isoxaflutole

RP 201772,异恶唑草酮,Merlin,RP-201772,RP201772

Others Others
Isoxaflutole (RP-201772) 是一种低毒除草剂,已作为阿特拉津的替代品上市销售。
T19507 Perfluamine

FTPA,Tris(perfluoropropyl)amine,Perfluorotripropylamine

Others Others
Perfluamine (FTPA) 是一种疏水性载液,可用作血液替代品。
T40969 Biotin-11-dUTP

Biotin-11-dUTP is a fluorescent substitute for dTTP.
T31707 Ethyl aspartylphenylalaninate

Others Others
Ethyl aspartylphenylalaninate is an artificial non-saccharide sweetener used as a sugar substitute.
T40970 Biotin-16-dUTP

Biotin-16-dUTP,Biotin-16-deoxyuridine-5'-triphosphate

Biotin-16-dUTP is a fluorescent substitute of dTTP.
T16799 RS-246204

Others Others
RS-246204 is an R-spondin-1 substitute compound. RS-246204 is able to initiate small intestinal organoids without the use of the R-spondin-1 protein.
T39438 Lithium dodecyl sulfate

Others Others
Lithium dodecyl sulfate is an anionic detergent and surfactant, suitable as a substitute for sodium dodecyl sulfate (SDS) in electrophoresis applications performed under lower temperatures. Lithium dodecyl sulfate is also applicable in the synthesis of nanomaterials and chromatography processes.
TP1694 Thymus peptide C

Thymus peptide C, a hormonal drug derived from the thymus glands of young calves, acts as a substitute for the physiological functions of the thymus.
T75341 Biotin-16-dUTP trisodium

Biotin-16-dUTP trisodium(Biotin-16-deoxyuridine-5'-triphosphate trisodium)可以通过酶促方式掺入DNA/cDNA中,作为其天然对应物dTTP的替代品。这种化合物主要用于生产用于多种检测应用的生物素化DNA探针。储存条件需避光。
T83675 Thio-NAD

Thionicotinamide NAD,Thionicotinamide adenine dinucleotide

Thio-NAD是一种经硫酮改造的信号分子和酶辅因子NAD+的衍生物。它能够在碱性磷酸酶(ALP)酶活性检测中替代NAD+作为辅因子。Thio-NAD被用作双酶循环ELISA的底物,以识别严重急性呼吸综合征冠状病毒2(SARS-CoV-2)刺突糖蛋白,亦称为表面糖蛋白,以及患者痰液中的活M. tuberculosis细菌。其在405 nm处表现出吸收,使其能够与其他辅因子区分开来。
T72696 UCK2 Inhibitor-3

Others Others
UCK2 Inhibitor-3是一款UCK2 (尿苷胞苷激酶2)的非竞争性抑制剂,其IC50值为16.6 μM。该化合物能在一定程度上补偿因感染或快速分裂的细胞中DHODH (二氢旋酸脱氢酶)功能的缺失,有效地挽救尿苷。此外,UCK2 Inhibitor-3还能抑制DNA聚合酶η和κ,其IC50值分别为56 μM和16 μM。

化合物

Substituted piperidines-1
Cat.No: T19567
Synonym:
Target: Others
Vitamin B3-d4
Cat.No: T85308
Synonym: Nicotinic acid-(ring-d4),Nicotinic acid-d4
Target: Autophagy
Isoxaflutole
Cat.No: T20721
Synonym: RP 201772,异恶唑草酮,Merlin,RP-201772,RP201772
Target: Others
Perfluamine
Cat.No: T19507
Synonym: FTPA,Tris(perfluoropropyl)amine,Perfluorotripropylamine
Target: Others
Biotin-11-dUTP
Cat.No: T40969
Synonym:
Target:
Ethyl aspartylphenylalaninate
Cat.No: T31707
Synonym:
Target: Others
Biotin-16-dUTP
Cat.No: T40970
Synonym: Biotin-16-dUTP,Biotin-16-deoxyuridine-5'-triphosphate
Target:
RS-246204
Cat.No: T16799
Synonym:
Target: Others
Lithium dodecyl sulfate
Cat.No: T39438
Synonym:
Target: Others
Thymus peptide C
Cat.No: TP1694
Synonym:
Target:
Biotin-16-dUTP trisodium
Cat.No: T75341
Synonym:
Target:
Thio-NAD
Cat.No: T83675
Synonym: Thionicotinamide NAD,Thionicotinamide adenine dinucleotide
Target:
UCK2 Inhibitor-3
Cat.No: T72696
Synonym:
Target: Others
Cat. No. Product Name Target Signaling Pathways
T1399 Sucralose

Trichlorosucrose,三氯蔗糖,E955

Others; Endogenous Metabolite Metabolism; Others
Sucralose 是一种无营养的人工甜味剂 (sweetener) 和代糖,它能够激活保守神经的禁食响应,从而刺激啮齿动物产生食欲。
T4723 D-Tagatose

塔格糖,D-(-)-Tagatose,D-塔格糖,d-tagatos

Others; Endogenous Metabolite Metabolism; Others
D-Tagatose (D-(-)-Tagatose) 是自然界中发现的一种罕见的单糖,具有益生元特性。它是研究II 型糖尿病的潜在抗糖尿病药物,也是帮助提升结肠有益细菌、预防结肠癌和抑制胆固醇的益生元。它是蔗糖的替代品,也是口香糖、果汁和饮料等食品中的低热量甜味剂。
T0585 Maltitol

麦芽糖醇,4-O-α-glucopyranosyl-D-sorbitol,Maltisorb

Others Others
Maltitol (4-O-α-glucopyranosyl-D-sorbitol) 是糖醇,它具有蔗糖 75-90% 的甜度,可用作糖的替代品。它也可用作明胶胶囊中的增塑剂,润肤剂和保湿剂。
TN6745 PALATINOSE

TNP-470,帕拉金糖水合物,Isomaltulose

Others Others
PALATINOSE (TNP-470) 是一种天然存在的二糖,由α-1,6-连接的葡萄糖和果糖组成。PALATINOSE 对肝脏代谢功能具有有益的影响,因此可能是蔗糖甜味剂的良好替代品。
T31520 Diplopterol

Diplopterol is biosynthetic of squalene for use in acetobacter pasteurii in a cell-free system. It is a hopanoid and can be used as a substitute for sterols.
T38706 Erlose

Others Others
Erlose, a trisaccharide present in soybean aphid honeydew and composed of sucrose, acts as a sweetener substitute to inhibit dental caries formation by oral microorganisms, primarily Streptococcus mutans. Erlose can serve as a reference compound in high-performance liquid chromatography (HPLC) methods employed for the analysis of sugar content in various food samples.

天然产物

Sucralose
Cat.No: T1399
Synonym: Trichlorosucrose,三氯蔗糖,E955
Target: Others, Endogenous Metabolite
D-Tagatose
Cat.No: T4723
Synonym: 塔格糖,D-(-)-Tagatose,D-塔格糖,d-tagatos
Target: Others, Endogenous Metabolite
Maltitol
Cat.No: T0585
Synonym: 麦芽糖醇,4-O-α-glucopyranosyl-D-sorbitol,Maltisorb
Target: Others
PALATINOSE
Cat.No: TN6745
Synonym: TNP-470,帕拉金糖水合物,Isomaltulose
Target: Others
Diplopterol
Cat.No: T31520
Synonym:
Target:
Erlose
Cat.No: T38706
Synonym:
Target: Others
Cat. No. Product Name Target Signaling Pathways
T11934 Macitentan-d4

Macitentan D4,ACT-064992 D4

Endothelin Receptor GPCR/G Protein
Macitentan-d4 (ACT-064992 D4) 是一种 Macitentan 氘代物,可被当作非多肽 ETA 和 ETB  (内皮素受体)双拮抗剂。Macitentan-d4 比 Macitentan 毒性更低,半衰期更长,可用于研究由内皮素受体介导介导的疾病。

同位素标记化合物

Macitentan-d4
Cat.No: T11934
Synonym: Macitentan D4,ACT-064992 D4
Target: Endothelin Receptor
TargetMol Loading
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