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Search Results for " rabies "

17

抑制剂 & 化合物

12

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
TP1871	Rabies Virus Glycoprotein
	Rabies Virus Glycoprotein is a 29 amino acid fragment generated from rabies virus glycoprotein (RVG). This peptide specifically binds to the acetylcholine receptor expressed by neuronal cells.
TP1871L	Rabies Virus Glycoprotein acetate
	Rabies Virus Glycoprotein acetate 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 TP1871L。
TP1553	Rabies Virus Glycoprotein TFA
	Rabies Virus Glycoprotein (TFA) is a kind of by the Rabies Virus Glycoprotein 29 - amino acid derived cell penetrating peptides, it can pass the blood brain barrier (BBB) into the brain cells.
T80338	RVG Rabies Virus Glycoprotein-29,RVG29,RDP
	RVG (RVG29) 是从狂犬病病毒糖蛋白衍生的肽，它能够结合到神经元细胞的烟碱乙酰胆碱受体 (AchR) α-7 亚基上。此外，RVG 促进了结核分枝杆菌抗原向抗原呈递细胞的递送效率。
T8701	GRP-60367	Others	Others
	GRP-60367 是一种小分子狂犬病病毒进入抑制剂，对某些 RABV 株具有纳摩尔作用效果。
T76555	Rabies Virus Matrix Protein Fragment(RV-MAT)
	Rabies VirusMatrix ProteinFragment (RV-MAT)为多肽类化合物，靶向细胞表面乙酰胆碱受体(AChR)。
T21980	PD 198306	MEK	MAPK
	PD 198306 是一种具有抗痛觉过敏作用的 MAPK/ERK 激酶 (MEK) 选择性抑制剂。 PD 198306 可降低链脲佐菌素诱导的活性 ERK1 水平升高。
TP2402	Peptide VF13N Epitope VF13N
	Peptide VF13N is a synthetic rabies virus glycoprotein T helper cell epitope.
T61763	GRP-60367 hydrochloride	Others	Others
	GRP-60367 hydrochloride is a novel small-molecule entry inhibitor of rabies virus (RABV), exhibiting nanomolar potency against select RABV strains. This first-in-class compound effectively targets the RABV G protein [1].
T77137	Rafivirumab
	Rafivirumab (CR57) 是一种用于预防狂犬病的抗狂犬病病毒 (rabies virus) 单克隆抗体。Rafivirumab 对广泛的 RABV 变体具有中和效力。Rafivirumab 可用于鸡尾酒疗法的研究。
T80589	Zamerovimab SYN023,CTB011
	Zamerovimab (CTB011; SYN023) 是一种由 CTB011 和 CTB012 组成的人源化单克隆抗体混合物，能与狂犬病病毒 (RABV) 糖蛋白的非重叠表位发生结合，且 CTB011 特异性结合抗原位点III。该混合物适用于狂犬病相关研究。
T77081	Mazorelvimab
	Mazorelvimab (SYN023) 是一种由 CTB011 和 CTB012 组成的抗狂犬病病毒 (RABV) 人源化单克隆抗体混合型。Mazorelvimab 可与RABV 糖蛋白 (G) 上的非重叠表位结合。Mazorelvimab 在预防狂犬病中有潜在应用。
T77161	Docaravimab
	Docaravimab为针对ERA (Evelyn-Rockitniki-Abelseth) 糖蛋白胞外域表位G-III的抗体，适用于狂犬病研究。
T80594	Ormutivimab rhRIG,NM57
	Ormutivimab (rhRIG) 为重组人源单克隆抗体，专一性靶向狂犬病病毒。该抗体能够中和不同株狂犬病病毒，并在狂犬病暴露后预防(PEP)模型中显示出高效力。
T78315	Foravirumab CR4098
	Foravirumab (CR4098)为针对狂犬病病毒糖蛋白的抗原位点III的单克隆抗体，适用于狂犬病相关研究。
T81789	Miromavimab M777-16-3
	Miromavimab (M777-16-3)为针对狂犬病毒ERAGP外域表位G-II的单克隆抗体(mAb)。
T62780	Antiviral agent 15	Others	Others
	Antiviral agent 15 (Compound 15f) 是一种 Clofazimine 衍生物，具有抗病毒活性。Antiviral agent 15 能够抑制狂犬病病毒 (EC50: 1.45 μM) 和假型 SARS-CoV-2 (EC50: 14.6 μM)。

化合物

Rabies Virus Glycoprotein

Cat.No: TP1871

Rabies Virus Glycoprotein acetate

Cat.No: TP1871L

Rabies Virus Glycoprotein TFA

Cat.No: TP1553

Cat.No: T80338

Synonym: Rabies Virus Glycoprotein-29,RVG29,RDP

Cat.No: T8701

Target: Others

Rabies Virus Matrix Protein Fragment(RV-MAT)

Cat.No: T76555

Cat.No: T21980

Target: MEK

Cat.No: TP2402

Synonym: Epitope VF13N

GRP-60367 hydrochloride

Cat.No: T61763

Target: Others

Cat.No: T77137

Cat.No: T80589

Synonym: SYN023,CTB011

Cat.No: T77081

Cat.No: T77161

Cat.No: T80594

Synonym: rhRIG,NM57

Cat.No: T78315

Synonym: CR4098

Cat.No: T81789

Synonym: M777-16-3

Antiviral agent 15

Cat.No: T62780

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-03222	Rabies virus (RABV) (strain ERA) Glycoprotein (His) Glycoprotein,G	RABV	E. coli
	Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells. Rabie...
TMPH-03219	Rabies virus (RABV) (strain India) Glycoprotein (His) Glycoprotein,G	RABV	P. pastoris (Yeast)
	Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells. Rabie...
TMPH-03226	Rabies virus (RABV) (strain PM1503/AVO1) Matrix Protein (GST) Phosphoprotein M2,Matrix protein,M	RABV	E. coli
	Plays a major role in assembly, budding and uncoating of virion after membrane fusion. Completely covers the ribonucleoprotein coil and keep it in condensed bullet-shaped form. Inhibits viral transcription and stimulates replication. Plays a major role in early induction of TRAIL-mediated apoptosis in infected neurons. Rabies virus (RABV) (strain PM1503/AVO1) Matrix Protein (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 49.9 kDa and the accessio...
TMPH-03220	Rabies virus (RABV) (strain India) Glycoprotein (His & SUMO) Glycoprotein,G	RABV	E. coli
	Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells. Rabie...
TMPH-03229	Rabies virus (RABV) (strain PM) Phosphoprotein (His) P,Protein M1,Phosphoprotein	RABV	E. coli
	Rabies virus (RABV) (strain PM) Phosphoprotein (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 37.2 kDa and the accession number is P69480.
TMPH-03228	Rabies virus (RABV) (strain SAD B19) Matrix Protein (His) Nucleoprotein,Nucleocapsid protein,N	RABV	E. coli
	Rabies virus (RABV) (strain SAD B19) Matrix Protein (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 54.7 kDa and the accession number is P16285.
TMPH-03223	Rabies virus (RABV) (strain HEP-Flury) Glycoprotein (His) G,Glycoprotein	RABV	Baculovirus Insect Cells
	Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells. Rabie...
TMPH-03225	Rabies virus (RABV) (strain CVS-11) Matrix Protein (His & Myc) Matrix protein,M,Phosphoprotein M2	RABV	E. coli
	Plays a major role in assembly, budding and uncoating of virion after membrane fusion. Completely covers the ribonucleoprotein coil and keep it in condensed bullet-shaped form. Inhibits viral transcription and stimulates replication. Plays a major role in early induction of TRAIL-mediated apoptosis in infected neurons. Rabies virus (RABV) (strain CVS-11) Matrix Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 28.1 kDa an...
TMPH-03224	Rabies virus (RABV) (strain HEP-Flury) Glycoprotein (E. coli, His) G,Glycoprotein	RABV	E. coli
	Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells. Rabie...
TMPY-06619	Rabies virus(RABV) (strain CVS-11) Nucleoprotein/NP Protein (His)	RABV	E. coli
	Rabies virus(RABV) (strain CVS-11) Nucleoprotein/NP Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 51.69 kDa and the accession number is Q8JXF6.
TMPH-03227	Rabies virus (RABV) (strain PM1503/AVO1) Matrix Protein (His) Nucleoprotein,Nucleocapsid protein,N	RABV	E. coli
	Rabies virus (RABV) (strain PM1503/AVO1) Matrix Protein (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 54.7 kDa and the accession number is P15197.
TMPH-03221	Rabies virus (RABV) (strain CVS-11) Glycoprotein (His & Myc & SUMO) G,Glycoprotein	RABV	E. coli
	Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells. Rabie...

重组蛋白

Rabies virus (RABV) (strain ERA) Glycoprotein (His)

Cat.No: TMPH-03222

Species: RABV

Expression System: E. coli

Rabies virus (RABV) (strain India) Glycoprotein (His)

Cat.No: TMPH-03219

Species: RABV

Expression System: P. pastoris (Yeast)

Rabies virus (RABV) (strain PM1503/AVO1) Matrix Protein (GST)

Cat.No: TMPH-03226

Species: RABV

Expression System: E. coli

Rabies virus (RABV) (strain India) Glycoprotein (His & SUMO)

Cat.No: TMPH-03220

Species: RABV

Expression System: E. coli

Rabies virus (RABV) (strain PM) Phosphoprotein (His)

Cat.No: TMPH-03229

Species: RABV

Expression System: E. coli

Rabies virus (RABV) (strain SAD B19) Matrix Protein (His)

Cat.No: TMPH-03228

Species: RABV

Expression System: E. coli

Rabies virus (RABV) (strain HEP-Flury) Glycoprotein (His)

Cat.No: TMPH-03223

Species: RABV

Expression System: Baculovirus Insect Cells

Rabies virus (RABV) (strain CVS-11) Matrix Protein (His & Myc)

Cat.No: TMPH-03225

Species: RABV

Expression System: E. coli

Rabies virus (RABV) (strain HEP-Flury) Glycoprotein (E. coli, His)

Cat.No: TMPH-03224

Species: RABV

Expression System: E. coli

Rabies virus(RABV) (strain CVS-11) Nucleoprotein/NP Protein (His)

Cat.No: TMPY-06619

Species: RABV

Expression System: E. coli

Rabies virus (RABV) (strain PM1503/AVO1) Matrix Protein (His)

Cat.No: TMPH-03227

Species: RABV

Expression System: E. coli

Rabies virus (RABV) (strain CVS-11) Glycoprotein (His & Myc & SUMO)

Cat.No: TMPH-03221

Species: RABV

Expression System: E. coli

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