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Search Results for " oligonucleotides "

Targets Recommended: Others

57

抑制剂 & 化合物

3

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T19065	Thiazole Orange	Others	Others
	Thiazole Orange 是不对称的花青素染料，能够与寡核苷酸偶联，制备荧光杂交探针。它可用于分析网织红细胞。
T18949	CY5-SE Cy5 NHS Ester,Sulfo-Cyanine5 Succinimidyl Ester,CY5-NHS酯	Others	Others
	CY5-SE (Sulfo-Cyanine5 Succinimidyl Ester) 是一种反应染料 (λex=649 nm，λem=670 nm)，可用于标记肽、蛋白质、寡核苷酸的氨基基团。
T8836	CY5-SE triethylamine salt Fluorolink Cy5 triethanolamine salt,Cy5-SE (triethylamine salt)	Others	Others
	CY5-SE triethylamine salt (Fluorolink Cy5 triethanolamine salt) 是一种用于标记肽, 蛋白质, 寡核苷酸的氨基基团的反应染料 (Ex=649 nm; Em=670 nm)。
T36687	Ac-rC Phosphoramidite	Nucleoside Antimetabolite/Analog	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Ac-rC Phosphoramidite 可以修饰二硫化磷酸寡核苷酸。
T18946	Cy3 NHS ester Cyanine3 NHS ester	Others	Others
	Cy3 NHS ester (Cyanine3 NHS ester) 是一种荧光染料，用于标记蛋白质、肽、抗体和寡核苷酸中的氨基。
T15025	CY5 Sulfo-Cyanine5	Others	Others
	Cy5 (Sulfo-Cyanine5) 是一种花菁类染料，用于标记肽、蛋白质和寡核苷酸中的氨基。
T18949L	CY5-SE Ditriethylamine salt CY5-SE Ditriethylamine salt(146368-14-1 Free base)	Others	Others
	CY5-SE Ditriethylamine salt 是用于标记寡核苷酸，肽，蛋白质的氨基基团的反应染料。激发波长 (nm): 649, 发射波长 (nm): 670
T13254L	UNC10217938A HCl UNC10217938A HCl(1347749-97-6 Free base),UNC7938 HCl	Others	Others
	UNC10217938A HCl (UNC7938 HCl) 是具有寡核苷酸 (oligonucleotides) 增强作用的 3-deazapteridine 类似物，通过调节寡核苷酸在细胞内的运输和从内体中的释放来增强寡核苷酸的作用。UNC10217938A HCl 还增强了 siRN 和反义寡核苷酸的作用。
TP1711	5-Tamra-DRVYIHP	Others	Others
	5-Tamra-DRVYIHP 是一种含有用寡核苷酸标记的罗丹明衍生物的多肽。
TD0091	Cy5.5 Sulfo-Cyanine5.5,脂性Cy5.5	Others	Others
	Cy5.5 (Sulfo-Cyanine5.5) 是一种近红外荧光染料 (Ex=673 nm, Em=707 nm)，可用于标记生物分子，如肽，蛋白质和寡核苷酸。
T38432	Cyanine5 NHS ester chloride	Others	Others
	Cyanine5 NHS ester chloride 是一种具有红色荧光的活性染料,需要少量的有机共溶剂(如DMF 或DMSO)用于标记肽、蛋白质和寡核苷酸中的氨基。
T18954L	CY7-SE Triethylamine (477908-53-5(free acid) )	Others	Others
	CY7-SE Triethylamine (477908-53-5(free acid) ) 是一种荧光标记剂（Ex=700-770 nm，Em=790 nm），用于标记蛋白质、肽、抗体和寡核苷酸。
T18956	CY7 Sulfo-Cyanine7	Others	Others
	CY7 (Sulfo-Cyanine7) 是一种荧光标记试剂 (Ex=750 nm，Em=773 nm)。Cyanine 染料可用于标记抗体，蛋白质，肽，寡聚核苷酸等。
T11086	DOTAP chloride (2,3-二油氧基丙基)三甲基氯化铵,1,2-Dioleoyl-3-trimethylammonium-propane chloride	Others	Others
	DOTAP chloride (1,2-Dioleoyl-3-trimethylammonium-propane chloride) 是高效的阳离子脂质，可以在不使用辅助脂质的情况下，作用于瞬时或者稳定转染 DNA (质粒、bacmids) 和修饰核酸 (反义寡核苷酸)。
T8902	DOTMA Trimethyl[2,3-(dioleyloxy)propyl]ammonium Chloride,N-(1-(2,3-dioleyloxy)propyl)-N,N,N-trimethylammonium	Others	Others
	DOTMA (N-(1-(2,3-dioleyloxy)propyl)-N,N,N-trimethylammonium) 作为 tetra-methylated DOTA 类似物，是一种阳离子脂类，被用作基因治疗的非病毒载体。它已被用作脂质体的成分，可用于封装 siRNA、microRNA 和寡核苷酸，并用于体外基因转染。在体外和体内均表现出良好的基因转染效果。DOTMA 诱导脂质体上的正电荷，从而促进脂质体与细胞膜的有效相互作用。
T9727	2'-Fluoro-2'-Deoxyadenosine	Nucleoside Antimetabolite/Analog	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	2′-Deoxy-2′-fluoroadenosine 可用于合成2 ' -脱氧-2 ' -氟修饰的寡核苷酸。它能被大肠杆菌嘌呤核苷磷酸化酶（PNP）有效地分解成毒性物 2-氟腺嘌呤，对表达大肠杆菌 PNP 的肿瘤表现出良好的体内活性。
T38496	IBU-DC Phosphoramidite	Others	Others
	IBU-DC Phosphoramidite is used for synthesis of oligonucleotides.
T37146	5'-O-DMT-2'-O-TBDMS-N-Bz-Adenosine	Others	Others
	5'-O-DMT-2'-O-TBDMS-N-Bz-Adenosine, an adenosine derivative, serves as an intermediate in the synthesis of oligonucleotides.
TD0035	Cy3 ethylenediamine 脂性Cy3, 乙二胺
	Cy3, ethylenediamine is a reactive dye used to label carboxyl groups of biological molecules. This reagent can be used to label dissolved proteins, peptides and oligonucleotides /DNA
T18950	CY5-YNE Sulfo-Cyanine5-alkyne	Others	Others
	CY5-YNE (Sulfo-Cyanine5-alkyne) is a reactive dye for the labeling of amino-groups in oligonucleotides, peptides, and proteins.
T18938	Cy2 (iodine)	Others	Others
	Cy2 is a cyanine dye used for labeling amino-groups in oligonucleotides, peptides, and proteins (λ excitation: 488 nm; λ emission: 520 nm).
T40800	5'-O-DMT-N2-ibu-dG 5'-O-DMT-N2-ibu-dG,N2-Isobutyryl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyguanosine	Others	Others
	5'-O-DMT-N2-ibu-dG, also known as N2-Isobutyryl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyguanosine, is a deoxynucleoside commonly employed in synthesizing oligonucleotides.
TD0089	Cy3 ethylenediamine 脂性Cy3, 乙二胺
	Cy3 ethylenediamine is a reactive dye that marks the carboxyl group of biomolecules. This reagent can label solubilized proteins, peptides and oligonucleotides/DNA
T34783	TAMRA-PEG4-NHS ester
	TAMRA-PEG4-NHS ester is a TAMRA red fluorescent dye derivative containing an NHS ester group which can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
T18947	Cy5.5-SE	Others	Others
	Cy5.5-SE is a cyanine dye, labeling amino-groups in oligonucleotides, peptides, and proteins.
TD0087	Sulfo-Cy5.5 荧光染料,Cy5.5
	Cy5.5 used to label biological molecules, such as peptides, proteins, and oligonucleotides. Cy5.5 is a near-infrared fluorescent dye (Ex=673 nm, Em=707 nm)
T38848	DMT-dI Phosphoramidite	Others	Others
	Phosphoramidite (a modified phosphoramidite monomer) is utilized in the synthesis of oligonucleotides.
T78405	Cyanine5 NHS ester iodide
	Cyanine5 NHS ester iodide，一种红色荧光染料，专用于肽、蛋白质与寡核苷酸的氨基标记。
T20901	m-PEG12-NHS ester	Others	Others
	M-PEG12-NHS ester is a PEG derivative containing an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label amine-modified oligonucleotides, the primary amines (-NH2) of proteins, and other amine-con
T75265	2'-OMe-Ac-C Phosphoramidite	Others	Others
	2'-OMe-Ac-C Phosphoramidite 是一种修饰过的的磷酰亚胺，可用于寡核苷酸的合成。
T18233	Mal-amido-PEG1-C2-NHS ester	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	Mal-amido-PEG1-C2-NHS ester is a noncleavable antibody-drug conjugate (ADC) linker that incorporates a maleimide functional group and an N-hydroxysuccinimide (NHS) ester. The NHS ester offers a means to specifically modify primary amines (-NH2) present in proteins, amine-modified oligonucleotides, and other amine-containing molecules[1][2].
T26250	Boc-NH-PEG4-NHS ester t-Boc-N-amido-PEG4-NHS ester	Others	Others
	t-Boc-N-amido-PEG4-NHS ester is a PEG derivative containing an NHS ester and a Boc-protected amino group. The NHS ester can be utilized to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
T18243	Mal-amido-PEG5-C2-NHS ester	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	Mal-amido-PEG10-C2-NHS ester is a noncleavable ADC linker, comprising a maleimide group and an NHS ester, which serves as a labeling agent for primary amines (-NH2) found in proteins, amine-modified oligonucleotides, and other amine-containing molecules[1][2].
T18944	CY3-YNE Sulfo-Cyanine3-alkyne	Others	Others
	CY3-YNE (Sulfo-Cyanine3-alkyne) is a dye for the labeling of oligonucleotides/DNA, soluble proteins, and peptides.
T74578	3'-DMTr-dG(iBu)	Others	Others
	3'-DMTr-dG(iBu)是一种应用于核酸合成的核苷，专用于合成用于研究乙型肝炎病毒(HBV)、丁型肝炎病毒(HDV)感染治疗的抗病毒剂，以及开发针对阿尔茨海默病和其他tau蛋白病治疗的寡核苷酸。
T18939	Cy2-SE (iodine) CY2-SE,Cyanine2 Succinimidyl Ester	Others	Others
	CY2-SE (Cyanine2 Succinimidyl Ester) is a dye for the labeling of amino-groups in oligonucleotides, peptides, and proteins (Excitation:492 nm, Emission: 510 nm).
T81912	LSP-GR3	iGluR	Membrane transporter/Ion channel; Neuroscience
	LSP-GR3为一种新型化学修饰RNA寡核苷酸，亦即剪接调控寡聚体(SMOs)，可特异性调控中枢神经系统内GluR的选择性剪接及GluR3-flip表达。
T18954	CY7-SE Sulfo-Cyanine7 Succinimidyl Ester,CY7-N-羟基琥珀酰胺酯	Others	Others
	CY7-SE (Sulfo-Cyanine7 Succinimidyl Ester) 是一种荧光标记试剂 (Ex=700-770 nm，Em=790 nm)。Cyanine 染料可用于标记蛋白质，肽，抗体，寡聚核苷酸等。
TD0036	Cy3 cadaverine 脂性Cy3,尸胺
	Cy3 cadaverine is a reactive dye used to label carboxyl groups of biological molecules. This reagent can be used to label dissolved proteins, peptides and oligonucleotides /DNA.
T18943	CY3-SE Sulfo-Cyanine3 Succinimidyl Ester,Cy3 NHS Ester	Others	Others
	CY3-SE (Sulfo-Cy3 NHS ester) is a reactive dye for the labeling of amino-groups in the soluble proteins, peptides, and oligonucleotides/DNA (Excitation: 555 nm, Emission: 570 nm).
T82647	Cyanine5 NHS ester bromide
	Cyanine5 NHS ester bromide 是用于标记肽、蛋白质和寡核苷酸氨基的活性染料。作为菁染料，该化合物特别适用于通过精氨酸残基对神经紧张素 (8-13) 进行荧光标记。
T15951	Mal-amido-PEG2-NHS ester	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	Mal-amido-PEG2-NHS ester is a noncleavable linker for antibody-drug conjugates (ADCs) that consists of a maleimide group and an NHS ester. The NHS ester allows for the labeling of protein primary amines (-NH2), amine-modified oligonucleotides, and other amine-containing molecules[1][2].
T81063	Sulfo-Cy5.5 Azide
	Sulfo-Cy5.5 Azide为含叠氮基团的点击化学试剂，兼具水溶性染料特性（Ex=673 nm, Em=707 nm），适用于肽、蛋白质及寡核苷酸的标记。
T83217	Abetimus LJP 394 free base	Others	Others
	Abetimus (LJP 394 free base)为一种由四个双链DNA (dsDNA) 寡核苷酸构成的免疫抑制剂，其作用机制为通过交联B细胞表面的抗dsDNA抗体，从而降低体内抗dsDNA抗体水平，具备作为系统性红斑狼疮研究工具的潜力。
T75357	DMTr-4'-F-U-CED-TBDMS phosphoramidite
	DMTr-4'-F-U-CED-TBDMS phosphoramidite (DMTr-4'-F-uridine-CED-TBDMS phosphoramidite) 是一种用于标记寡核苷酸的染料试剂，可用于研究 RNA 疗法。DMTr-4'-F-U-CED-TBDMS phosphoramidite 代表了一种用于阐明 RNA 结构的广泛用途的探针。储存方式：避光。
TP1743	MPG, HIV related
	MPG, a 27-amino acid peptide compound, is derived from the fusion peptide domain of HIV-1 gp41 and the nuclear localisation sequence of SV40 large T antigen. As a potent delivery agent, MPG enables efficient and widespread transport of nucleic acids and oligonucleotides into cultured cells.
T18235	Mal-amido-PEG10-C2-NHS ester	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	Mal-amido-PEG10-C2-NHS ester is a noncleavable antibody-drug conjugate (ADC) linker that consists of a maleimide group and an N-hydroxysuccinimide (NHS) ester. The NHS ester enables efficient labeling of primary amines (-NH2) in proteins, amine-modified oligonucleotides, and other amine-containing molecules[1][2].
T81640	NSC15520	Others	Others
	NSC15520是一种小分子RPA抑制剂，特异性结合RPA的N端DNA结合域(DBD)，阻断其与p53或RAD9的相互作用。它还能够抑制双链DNA(dsDNA)寡核苷酸的螺旋不稳定性，影响DNA复制、修复、重组及损伤反应信号。
T32121	Hydroxy-PEG3-NHS	Others	Others
	Hydroxy-PEG3-NHS is a PEG derivative containing a hydroxyl group with an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. T
T29389	3-Azidopropionic Acid Sulfo-NHS Ester	Others	Others
	3-Azidopropionic Acid Sulfo-NHS Ester is a water-soluble compound containing an azide group and an NHS ester. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The NHS ester can be used to label the p

化合物

Thiazole Orange

Cat.No: T19065

Target: Others

Cat.No: T18949

Synonym: Cy5 NHS Ester,Sulfo-Cyanine5 Succinimidyl Ester,CY5-NHS酯

Target: Others

CY5-SE triethylamine salt

Cat.No: T8836

Synonym: Fluorolink Cy5 triethanolamine salt,Cy5-SE (triethylamine salt)

Target: Others

Ac-rC Phosphoramidite

Cat.No: T36687

Target: Nucleoside Antimetabolite/Analog

Cat.No: T18946

Synonym: Cyanine3 NHS ester

Target: Others

Cat.No: T15025

Synonym: Sulfo-Cyanine5

Target: Others

CY5-SE Ditriethylamine salt

Cat.No: T18949L

Synonym: CY5-SE Ditriethylamine salt(146368-14-1 Free base)

Target: Others

UNC10217938A HCl

Cat.No: T13254L

Synonym: UNC10217938A HCl(1347749-97-6 Free base),UNC7938 HCl

Target: Others

5-Tamra-DRVYIHP

Cat.No: TP1711

Target: Others

Cat.No: TD0091

Synonym: Sulfo-Cyanine5.5,脂性Cy5.5

Target: Others

Cyanine5 NHS ester chloride

Cat.No: T38432

Target: Others

CY7-SE Triethylamine (477908-53-5(free acid) )

Cat.No: T18954L

Target: Others

Cat.No: T18956

Synonym: Sulfo-Cyanine7

Target: Others

Cat.No: T11086

Synonym: (2,3-二油氧基丙基)三甲基氯化铵,1,2-Dioleoyl-3-trimethylammonium-propane chloride

Target: Others

Cat.No: T8902

Synonym: Trimethyl[2,3-(dioleyloxy)propyl]ammonium Chloride,N-(1-(2,3-dioleyloxy)propyl)-N,N,N-trimethylammonium

Target: Others

2'-Fluoro-2'-Deoxyadenosine

Cat.No: T9727

Target: Nucleoside Antimetabolite/Analog

IBU-DC Phosphoramidite

Cat.No: T38496

Target: Others

5'-O-DMT-2'-O-TBDMS-N-Bz-Adenosine

Cat.No: T37146

Target: Others

Cy3 ethylenediamine

Cat.No: TD0035

Synonym: 脂性Cy3, 乙二胺

Cat.No: T18950

Synonym: Sulfo-Cyanine5-alkyne

Target: Others

Cat.No: T18938

Target: Others

5'-O-DMT-N2-ibu-dG

Cat.No: T40800

Synonym: 5'-O-DMT-N2-ibu-dG,N2-Isobutyryl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyguanosine

Target: Others

Cy3 ethylenediamine

Cat.No: TD0089

Synonym: 脂性Cy3, 乙二胺

TAMRA-PEG4-NHS ester

Cat.No: T34783

Cat.No: T18947

Target: Others

Cat.No: TD0087

Synonym: 荧光染料,Cy5.5

DMT-dI Phosphoramidite

Cat.No: T38848

Target: Others

Cyanine5 NHS ester iodide

Cat.No: T78405

m-PEG12-NHS ester

Cat.No: T20901

Target: Others

2'-OMe-Ac-C Phosphoramidite

Cat.No: T75265

Target: Others

Mal-amido-PEG1-C2-NHS ester

Cat.No: T18233

Target: Others, ADC Linker

Boc-NH-PEG4-NHS ester

Cat.No: T26250

Synonym: t-Boc-N-amido-PEG4-NHS ester

Target: Others

Mal-amido-PEG5-C2-NHS ester

Cat.No: T18243

Target: Others, ADC Linker

Cat.No: T18944

Synonym: Sulfo-Cyanine3-alkyne

Target: Others

3'-DMTr-dG(iBu)

Cat.No: T74578

Target: Others

Cy2-SE (iodine)

Cat.No: T18939

Synonym: CY2-SE,Cyanine2 Succinimidyl Ester

Target: Others

Cat.No: T81912

Target: iGluR

Cat.No: T18954

Synonym: Sulfo-Cyanine7 Succinimidyl Ester,CY7-N-羟基琥珀酰胺酯

Target: Others

Cat.No: TD0036

Synonym: 脂性Cy3,尸胺

Cat.No: T18943

Synonym: Sulfo-Cyanine3 Succinimidyl Ester,Cy3 NHS Ester

Target: Others

Cyanine5 NHS ester bromide

Cat.No: T82647

Mal-amido-PEG2-NHS ester

Cat.No: T15951

Target: Others, ADC Linker

Sulfo-Cy5.5 Azide

Cat.No: T81063

Cat.No: T83217

Synonym: LJP 394 free base

Target: Others

DMTr-4'-F-U-CED-TBDMS phosphoramidite

Cat.No: T75357

MPG, HIV related

Cat.No: TP1743

Mal-amido-PEG10-C2-NHS ester

Cat.No: T18235

Target: Others, ADC Linker

Cat.No: T81640

Target: Others

Hydroxy-PEG3-NHS

Cat.No: T32121

Target: Others

3-Azidopropionic Acid Sulfo-NHS Ester

Cat.No: T29389

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPK-01028	BSPII Protein, Mouse, Recombinant (His) IBSP,SP II,BSP,BSP II,BNSP,BSP-II,BSP 2,SPII,SP-II	Mouse	HEK293 Cells
	Osteopontin (OPN), bone sialoprotein (BSPII), and osteonectin (ON) belong to a family of glycoproteins, which have been linked to cancer metastasis and progression. Here, we report on the selection of antisense oligonucleotides (ASOs), which are effective in reducing their protein levels.
TMPH-01800	Nucleolin Protein, Human, Recombinant (His) NCL,Protein C23,Nucleolin	Human	P. pastoris (Yeast)
	Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. May play a role in the process of transcriptional elongation. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats. Nucleolin Protein, ...
TMPH-01239	XPC Protein, Human, Recombinant (His) Xeroderma pigmentosum group C-complementing protein,p125,XPC...	Human	E. coli
	Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein i...

重组蛋白

BSPII Protein, Mouse, Recombinant (His)

Cat.No: TMPK-01028

Species: Mouse

Expression System: HEK293 Cells

Nucleolin Protein, Human, Recombinant (His)

Cat.No: TMPH-01800

Species: Human

Expression System: P. pastoris (Yeast)

XPC Protein, Human, Recombinant (His)

Cat.No: TMPH-01239

Species: Human

Expression System: E. coli

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