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Search Results for " nucleotides "

Targets Recommended: Others

29

抑制剂 & 化合物

11

天然产物

4

化合物库

22

重组蛋白

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Cat. No.	Product Name
L1600	激酶抑制剂库		2720 compounds
	2720 种激酶抑制剂/调节剂的独特集合，用于特定靶向激酶，可用于高通量筛选和高内涵筛选；
L1720	核苷类化合物库		334 compounds
	334 种核苷类化合物，包括核苷酸、核苷酸类似物及衍生物等，适用于抗病毒、抗肿瘤、抗真菌、抗抑郁等药物的研发；
L2501	人内源代谢化合物库 Plus		1283 compounds
	1283种内源性生物活性化合物的独特集合，用于高通量、高内涵筛选。
L2570	人代谢物化合物库		4454 compounds
	4454 种人代谢物的独特集合，用于高通量、高内涵筛选；

化合物库

激酶抑制剂库

Cat.No: L1600

Compounds: 2720

核苷类化合物库

Cat.No: L1720

Compounds: 334

人内源代谢化合物库 Plus

Cat.No: L2501

Compounds: 1283

人代谢物化合物库

Cat.No: L2570

Compounds: 4454

Cat. No.	Product Name	Target	Signaling Pathways
T14049	5-FAM SE	Others	Others
	5-FAM SE 是单一异构体，是用于标记肽、蛋白质和核苷酸的荧光标记试剂。它能够与胺反应，产生稳定的胺结合物。
T7092	NADPH tetrasodium salt	Others; Ferroptosis; Endogenous Metabolite	Apoptosis; Metabolism; Others
	NADPH tetrasodium salt 是电子受体烟酰胺腺嘌呤二核苷酸磷酸的还原形式，在各种生物反应中充当电子供体。NADPH tetrasodium salt 也是一种内源性铁死亡抑制剂。
T18901	6-FAM SE 6-羧基荧光素琥珀酰亚胺醚,6-Carboxyfluorescein N-succinimidyl ester	Others	Others
	6-FAM SE (6-Carboxyfluorescein N-succinimidyl ester) 是羧基荧光素的同分异构体，常用于核酸测序和标记核苷酸。
T4057	Hoechst 33258 trihydrochloride Hoechst 33258,Pibenzimol,Bisbenzimide,H 33258 trihydrochloride,bisBenzimide H 33258 trihydrochloride,HOE 33258	Parasite	Microbiology/Virology
	Hoechst 33258 trihydrochloride (Bisbenzimide) 是一种能够用于 DNA 染色的荧光染料。
T10509	Xanthine oxidase-IN-1 4-(3-Cyano-5,6-difluoroindol-1-yl)-2-hydroxybenzoic acid	Xanthine Oxidase	Metabolism
	Xanthine oxidase-IN-1是一种有效的黄嘌呤氧化酶抑制剂(IC50值:6.5 nM),是一种利用核酸和核苷酸介质降解产生的生物活性核苷酸在嘌呤分解代谢中起核心作用的化合物，
T40192	dGTP 2′-脱氧鸟苷 5′-(四氢三磷酸酯),2'-Deoxyguanosine-5'-triphosphate	Nucleoside Antimetabolite/Analog; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	dGTP（2'-Deoxyguanosine-5'-triphosphate）作为脱氧核糖核酸（DNA）合成的基本单元，属于鸟苷核苷酸，对8-O-GDP、8-O-dGTP、8-O-GTP及8-O-dGTP的氧化损伤具有高度敏感性。
T61860	Enpp-1-IN-9	Others	Others
	Enpp-1-IN-9, a powerful inhibitor of ectonucleotide pyrophosphatase-phosphodiesterase 1 (ENPP1), exhibits wide substrate specificity, capable of cleaving various bonds such as phosphodiester bonds of nucleotides and nucleotide sugars, as well as pyrophosphate bonds of nucleotides and nucleotide sugars. Its potential application lies in the fields of cancer and infectious disease research[1].
T62085	Enpp-1-IN-5	Others	Others
	Enpp-1-IN-5 是一种有效的外核苷酸焦磷酸酶-磷酸二酯酶 1 (enpp-1) 抑制剂。ENPP 1 显示出广泛的特异性，能够切割多种底物（包括核苷酸和核苷酸糖的磷酸二酯键、核苷酸和核苷酸糖的焦磷酸键）。 Enpp-1-IN-5 具有潜力进行癌症和传染病的研究。
T62368	Enpp-1-IN-7	Others	Others
	Enpp-1-IN-7 是一种有效的外核苷酸焦磷酸酶-磷酸二酯酶 1 (enpp-1) 抑制剂。ENPP 1 具有广泛的特异性，能够切割多种底物（包括核苷酸和核苷酸糖的磷酸二酯键以及核苷酸和核苷酸糖的焦磷酸键）。 Enpp-1-IN-7 具有潜力进行癌症和传染病的研究。
T25324	Dichloromethotrexate NSC 29630,3988-B-129-4,NSC29630,Dichloroamethopterin,NSC-29630	Others	Others
	Dichloromethotrexate is an enzyme dihydrofolate reductase inhibitor, thus preventing the synthesis of purine nucleotides and thymidylates and inhibiting DNA and RNA synthesis. This agent is metabolized and excreted by the liver.
T37895	4-Nitrophenyl Phenylphosphonate	Others	Others
	4-Nitrophenyl phenylphosphonate is a substrate for 5'-nucleotide phosphodiesterases. It is a more preferable substrate to 5'-nucleotide phosphodiesterases than naturally occurring nucleotides or bis(4-nitrophenyl) phosphate because of its stability, ease of synthesis, and higher rate of hydrolysis under saturating conditions.
TD0074	N-Succinimidyl 7-hydroxycoumarin-3-carboxylate 7-羟基-3-羧基香豆素琥珀酰亚胺酯,7-Hydroxycoumarin-3-carboxylic acid, succinimidyl ester
	7-Hydroxycoumarin-3-carboxylic acid, SE is the amine-reactive succinimidyl ester of 7-Hydroxycoumarin-3-carboxylic acid. This coumarin is also increasingly used to label peptides, nucleotides and carbohydrates.
TD0075	7-Hydroxy-4-methylcoumarin-3-acetic acid
	7-Hydroxy-4-methylcoumarin-3-acetic acid is a blue fluorophore that has pH-dependent and environment-sensitive fluorescence. This coumarin is increasingly used to label peptides, nucleotides and carbohydrates.
TNU1204	3’-Azido-2’,3’-dideoxyuridine 5’-phosphate diammonium salt	Others	Others
	Nucleoside Derivatives - Phosphorus-containing nucleotides, Azido-nucleosides, 2’,3’-Dideoxy-nucleosides
T76214	5′-Nucleotidase	Others	Others
	5′-Nucleotidase (CD73) 是一种作为胞外酶存在的内在膜糖蛋白。5′-Nucleotidase 催化 5-核苷酸水解成相应的核苷。
TD0031	Cy3 diacid 脂性Cy3双酸
	Cy3 diacid is often used in biomolecular labeling, fluorescence imaging and other fluorescence biological analysis.They are widely used in polypeptides, proteins, nucleotides and so on.
TD0032	Cy3 diacid, SE 脂性Cy3双酸-N-羟基琥珀酰亚胺酯
	Cy3 diacid, SE is often used in biomolecular labeling, fluorescence imaging and other fluorescence biological analysis.They are widely used in polypeptides, proteins, nucleotides and so on.
T35703	2-hydroxy Stearic Acid methyl ester	Others	Others
	2-hydroxy Stearic acid is a hydroxylated fatty acid methyl ester that broadens phase transition in dimyristoylphosphatidylcholine (DMPC) lipid membranes. It has been used in the synthesis of lipid-nucleotide conjugate anti-HIV agents to increase phosphodiester bond cleavage and the amount of liberated intracellular nucleotides.
T38472	Phosphoribosyl pyrophosphate pentasodium PRPPpentasodium,磷酸核糖焦磷酸	Others	Others
	Phosphoribosyl pyrophosphate (PRPP) pentasodium is a vital metabolite essential for the biosynthesis of purine and pyrimidine nucleotides, as well as the amino acids histidine and tryptophan. It also acts as a precursor for the important cofactors NAD and NADP.
T40753	Cytidine-5'-triphosphate Cytidine triphosphate,Cytidine-5'-triphosphate,5'-CTP	Others	Others
	Cytidine 5'-triphosphate (5'-CTP), also known as cytidine triphosphate, is a nucleoside triphosphate that plays a crucial role as a building block for nucleotides and nucleic acids, as well as lipid biosynthesis. It is synthesized through the catalytic action of cytidine triphosphate synthase, which converts uridine 5'-triphosphate (UTP) to cytidine 5'-triphosphate. Cytidine 5'-triphosphate is an essential biomolecule in T. gondii's de novo pyrimidine biosynthetic pathway.
T76138	Phosphodiesterase	Others	Others
	Phosphodiesterase(PDE) 是一种可以催化环核苷酸3 '环磷酸键水解的酶，常用于生化研究。Phosphodiesterase 可作为第二信使分子 cAMP 和 cGMP 介导的信号转导的重要调节因子。根据其对环核苷酸的特异性也可以分别不同类型，如 PDE1-PDE11，在多种疾病方面也具有一定的潜力。
T62459	Enpp-1-IN-8	Others	Others
	Enpp-1-IN-8 是一种有效的外核苷酸焦磷酸酶-磷酸二酯酶 1 (enpp-1) 抑制剂。其中 ENPP 1 具有广泛特异性，能够切割多种底物（包括核苷酸和核苷酸糖的磷酸二酯键以及核苷酸和核苷酸糖的焦磷酸键）。 Enpp-1-IN-8 具有潜力进行癌症和传染病的研究。
T63246	BMS-566419	Others	Others
	BMS-566419 是基于吖啶酮的肌苷 5'-一磷酸脱氢酶 (IMPDH) 抑制剂。其中肌苷一磷酸脱氢酶 (IMPDH) 是一种鸟苷核苷酸从头合成的关键酶。BMS-566419 在临床上具有研究移植排斥的实用性。
T63985	Trimetrexate glucuronate	Others	Others
	Trimetrexate glucuronate (NSC 352122) 是一种叶酸拮抗剂，能够抑制二氢叶酸还原酶 (dihydrofolate reductase)，进而阻断嘌呤核苷酸和胸苷酸的合成，影响 DNA 和 RNA 合成，表现出潜在的抗肿瘤效果。
T73930	(-)-Eseroline fumarate	Others	Others
	(-)-Eseroline fumarate 是一种 AChE 抑制剂 Physostigmine 的代谢产物。(-)-Eseroline fumarate 引起癌细胞的乳酸脱氢酶 (LDH) 泄漏。(-)-Eseroline fumarate 还诱导神经元细胞释放腺嘌呤核苷酸和5-羟色胺 (5-HT)，从而诱导细胞死亡。(-)-Eseroline fumarate 抑制小鼠输精管和豚鼠回肠的电诱发抽搐。
T74693	CDN-A	Others	Others
	CDN-A为一种环二核苷酸，主要用于抗体-活性分子偶联物(ADC)的合成。作为先天免疫及适应性免疫反应的关键激活剂，环状二核苷酸能由内源性外来DNA或侵入性细菌病原体生成，在人体内通过促进干扰素基因表达激活先天免疫系统。
T35575	Aldehyde Reactive Probe (trifluoroacetate salt)	Others	Others
	DNA is continually damaged by endogenous and environmental agents leading to the formation of abasic (apurinic/apyrimidinic, AP) sites that are disruptive to DNA synthesis. Aldehyde Reactive Probe (ARP) is a biotinylated reagent for the detection and quantification of AP sites in damaged DNA. ARP reacts with aldehyde groups formed when reactive oxygen species depurinate DNA, resulting in covalent linkage of biotin to these AP sites. The biotin-tagged DNA can then be detected using common avidin-...
T35572	Adenosine 3',5'-diphosphate sodium salt 3'-Phosphoadenosine 5'-phosphate	Endogenous Metabolite	Metabolism
	Adenosine 3',5'-diphosphate sodium salt 是一种羟类固醇磺基转移酶 (hydroxysteroid sulfotransferases) 抑制剂，是一种腺嘌呤核苷酸，在戊糖核糖的 3'和 5'位置含有一个磷酸基团。Adenosine 3',5'-diphosphate (sodium salt)是 3'-phosphoadenosine 5'-phosphosulfonate (PAPS) 的产物，是磺基转移酶（SULTs）的辅助因子，已被用于研究 SULTs 的动力学特性和结构。
T35573	Adenosine 5’-methylenediphosphate (hydrate)	Others	Others
	Adenosine 5’-methylenediphosphate is an inhibitor of ecto-5’-nucleotidase, also known as CD73, with a Kivalue of 37 nM.1It inhibits cAMP accumulation induced by adenosine 5’-monophosphate , adenosine 5’-diphosphate , or adenosine 5’-triphosphate but not adenosine in VA-13 human fibroblasts when used at a concentration of 100 μM. Adenosine 5’-methylenediphosphate reduces proliferation of U138MG glioma cells, as well as inhibits the invasion and migration of MHCC97H hepatocellular carcinoma (HCC) ...

化合物

Cat.No: T14049

Target: Others

NADPH tetrasodium salt

Cat.No: T7092

Target: Others, Ferroptosis, Endogenous Metabolite

Cat.No: T18901

Synonym: 6-羧基荧光素琥珀酰亚胺醚,6-Carboxyfluorescein N-succinimidyl ester

Target: Others

Hoechst 33258 trihydrochloride

Cat.No: T4057

Synonym: Hoechst 33258,Pibenzimol,Bisbenzimide,H 33258 trihydrochloride,bisBenzimide H 33258 trihydrochloride,HOE 33258

Target: Parasite

Xanthine oxidase-IN-1

Cat.No: T10509

Synonym: 4-(3-Cyano-5,6-difluoroindol-1-yl)-2-hydroxybenzoic acid

Target: Xanthine Oxidase

Cat.No: T40192

Synonym: 2′-脱氧鸟苷 5′-(四氢三磷酸酯),2'-Deoxyguanosine-5'-triphosphate

Target: Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis

Cat.No: T61860

Target: Others

Cat.No: T62085

Target: Others

Cat.No: T62368

Target: Others

Dichloromethotrexate

Cat.No: T25324

Synonym: NSC 29630,3988-B-129-4,NSC29630,Dichloroamethopterin,NSC-29630

Target: Others

4-Nitrophenyl Phenylphosphonate

Cat.No: T37895

Target: Others

N-Succinimidyl 7-hydroxycoumarin-3-carboxylate

Cat.No: TD0074

Synonym: 7-羟基-3-羧基香豆素琥珀酰亚胺酯,7-Hydroxycoumarin-3-carboxylic acid, succinimidyl ester

7-Hydroxy-4-methylcoumarin-3-acetic acid

Cat.No: TD0075

3’-Azido-2’,3’-dideoxyuridine 5’-phosphate diammonium salt

Cat.No: TNU1204

Target: Others

5′-Nucleotidase

Cat.No: T76214

Target: Others

Cat.No: TD0031

Synonym: 脂性Cy3双酸

Cat.No: TD0032

Synonym: 脂性Cy3双酸-N-羟基琥珀酰亚胺酯

2-hydroxy Stearic Acid methyl ester

Cat.No: T35703

Target: Others

Phosphoribosyl pyrophosphate pentasodium

Cat.No: T38472

Synonym: PRPPpentasodium,磷酸核糖焦磷酸

Target: Others

Cytidine-5'-triphosphate

Cat.No: T40753

Synonym: Cytidine triphosphate,Cytidine-5'-triphosphate,5'-CTP

Target: Others

Phosphodiesterase

Cat.No: T76138

Target: Others

Cat.No: T62459

Target: Others

Cat.No: T63246

Target: Others

Trimetrexate glucuronate

Cat.No: T63985

Target: Others

(-)-Eseroline fumarate

Cat.No: T73930

Target: Others

Cat.No: T74693

Target: Others

Aldehyde Reactive Probe (trifluoroacetate salt)

Cat.No: T35575

Target: Others

Adenosine 3',5'-diphosphate sodium salt

Cat.No: T35572

Synonym: 3'-Phosphoadenosine 5'-phosphate

Target: Endogenous Metabolite

Adenosine 5’-methylenediphosphate (hydrate)

Cat.No: T35573

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T0746	Orotic acid 乳清酸,Vitamin B13,6-Carboxyuracil	Nucleoside Antimetabolite/Analog; Dehydrogenase; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	Orotic acid (Vitamin B13) 是一种嘧啶核苷酸和 RNA 生物合成的前体，从线粒体二氢乳清酸脱氢酶 (DHODH) 中释放，通过细胞质 UMP 合酶转化为 UMP。它可引起大鼠肝脂肪变性和肝肿大，是尿素循环异常的常规新生儿筛查中的一种测量指标。
T3271	Orotic acid zinc 乳清酸锌二水合物,Orotic acid zinc salt dihydrate,Zinc Orotate	Nucleoside Antimetabolite/Analog; Others; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Others
	Orotic acid zinc (Zinc Orotate) 是一种嘧啶核苷酸和 RNA 生物合成的前体，从线粒体二氢乳清酸脱氢酶 (DHODH) 中释放，通过细胞质 UMP 合酶转化为 UMP。它可引起大鼠肝脂肪变性和肝肿大，是尿素循环异常的常规新生儿筛查中的一种测量指标。
T2A2537	Guanine 鸟嘌呤;2-氨基次黄嘌呤;2-氨基-6-羟基嘌呤;鸟便嘌呤;鸟粪素;海鸟粪碱;鸟粪环;亚氨基二氧化嘌呤,Pearl essence,Mearlmaid,鸟嘌呤,2-Aminohypoxanthine	Others; DNA/RNA Synthesis; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Others
	Guanine (2-Aminohypoxanthine) 是一种嘌呤碱基，是核酸中核苷酸的组成部分，由具有共轭双键的稠合嘧啶 - 咪唑环系统组成。
T3S0156	Atractyloside potassium salt Atractyloside Dipotassium Salt,苍术苷钾盐,苍术苷二钾盐	Others	Others
	Atractyloside potassium salt (Atractyloside Dipotassium Salt) 是一种从苍术果实中分离出得到的二萜苷类化合物，具有毒性。它能抑制大鼠心脏线粒体膜的氯离子通道。它是高效、特异性的线粒体 ADP/ATP 转运 (ADP/ATP transport) 抑制剂。
TMA2440	Uridine 5'-monophosphate disodium salt 尿苷-5'-单磷酸二钠盐,Disodium UMP,尿苷酸二钠盐,Disodium uridine-5'-monophosphate,5'-UMP disodium salt,Disodium 5'-Uridylate	Others	Others
	Uridine 5'-monophosphate disodium salt (Disodium UMP) 是合成 RNA 的一种重要成分。
T1705	5-Amino-3H-imidazole-4-Carboxamide 4-Amino-5-imidazolecarboxamide,AICA,4-氨基-5-咪唑甲酰胺,5-Aminoimidazole-4-carboxamide	Endogenous Metabolite	Metabolism
	5-Amino-3H-imidazole-4-Carboxamide (AICA) 是一种合成嘌呤（尤其是核碱基腺嘌呤和鸟嘌呤）的重要前体。
T2O2731	L-Aspartic acid L-天冬氨酸,L-天冬氨酸；L-天冬碱;L-酰胺天冬酸；L-天冬酰胺一水物,Aspatofort,Asparagic acid	Others; Endogenous Metabolite	Metabolism; Others
	L-Aspartic acid (Aspatofort) 是一种氨基酸，是结肠特异性药物输送的前体药物。
T4809	Pyrimidine 嘧啶,Metadiazine	Others; Endogenous Metabolite	Metabolism; Others
	Pyrimidine (Metadiazine) 是内源性代谢产物的一种。
T8047	Menthyl acetate 乙酸-L-孟酯,(1R)-(-)-Menthyl acetate,(-)-Menthyl acetate,L-Menthyl acetate	Others	Others
	Menthyl acetate 是一种可有效增强 5-氨基乙酰丙酸 (ALA) 皮肤渗透的 L-薄荷醇衍生物。
T4758	2'-Deoxycytidine Cytosine deoxyribonucleoside,2'-Deoxycytidine monohydrate,2(1H)-Pyrimidinone,Cytosine deoxyriboside,Deoxyribose cytidine,Deoxycytidine,2'-脱氧胞嘧啶核苷一水合物	Endogenous Metabolite	Metabolism
	2'-Deoxycytidine 是由胞嘧啶和脱氧核糖组成的DNA的主要核苷之一，抑制溴脱氧尿苷 (Brdu) 的生物效应。核苷仅由与嘌呤或嘧啶碱相连的戊糖组成，没有磷酸基团。当N1与脱氧核糖的C1连接时，由胞嘧啶和脱氧核糖形成脱氧核苷和核苷酸；脱氧胞苷单磷酸(dCMP)，脱氧胞苷二磷酸(dCDP)，脱氧胞苷三磷酸(dCTP)。CTP是RNA(核糖核酸)中胞苷的来源，脱氧胞苷三磷酸(dCTP)是DNA(脱氧核糖核酸)中脱氧胞苷的来源。
T19267	D-Ribose 5-phosphate	Others	Others
	Ribose 5-phosphate is the intermediate product of the oxidative branch of the pentose phosphate pathway (PPP) and the final product of the non-oxidative branch of PPP. Ribose 5-phosphate is used in the synthesis of nucleotides and nucleic acids.

天然产物

Cat.No: T0746

Synonym: 乳清酸,Vitamin B13,6-Carboxyuracil

Target: Nucleoside Antimetabolite/Analog, Dehydrogenase, Endogenous Metabolite

Orotic acid zinc

Cat.No: T3271

Synonym: 乳清酸锌二水合物,Orotic acid zinc salt dihydrate,Zinc Orotate

Target: Nucleoside Antimetabolite/Analog, Others, Endogenous Metabolite

Cat.No: T2A2537

Synonym: 鸟嘌呤;2-氨基次黄嘌呤;2-氨基-6-羟基嘌呤;鸟便嘌呤;鸟粪素;海鸟粪碱;鸟粪环;亚氨基二氧化嘌呤,Pearl essence,Mearlmaid,鸟嘌呤,2-Aminohypoxanthine

Target: Others, DNA/RNA Synthesis, Endogenous Metabolite

Atractyloside potassium salt

Cat.No: T3S0156

Synonym: Atractyloside Dipotassium Salt,苍术苷钾盐,苍术苷二钾盐

Target: Others

Uridine 5'-monophosphate disodium salt

Cat.No: TMA2440

Synonym: 尿苷-5'-单磷酸二钠盐,Disodium UMP,尿苷酸二钠盐,Disodium uridine-5'-monophosphate,5'-UMP disodium salt,Disodium 5'-Uridylate

Target: Others

5-Amino-3H-imidazole-4-Carboxamide

Cat.No: T1705

Synonym: 4-Amino-5-imidazolecarboxamide,AICA,4-氨基-5-咪唑甲酰胺,5-Aminoimidazole-4-carboxamide

Target: Endogenous Metabolite

L-Aspartic acid

Cat.No: T2O2731

Synonym: L-天冬氨酸,L-天冬氨酸；L-天冬碱;L-酰胺天冬酸；L-天冬酰胺一水物,Aspatofort,Asparagic acid

Target: Others, Endogenous Metabolite

Cat.No: T4809

Synonym: 嘧啶,Metadiazine

Target: Others, Endogenous Metabolite

Menthyl acetate

Cat.No: T8047

Synonym: 乙酸-L-孟酯,(1R)-(-)-Menthyl acetate,(-)-Menthyl acetate,L-Menthyl acetate

Target: Others

2'-Deoxycytidine

Cat.No: T4758

Synonym: Cytosine deoxyribonucleoside,2'-Deoxycytidine monohydrate,2(1H)-Pyrimidinone,Cytosine deoxyriboside,Deoxyribose cytidine,Deoxycytidine,2'-脱氧胞嘧啶核苷一水合物

Target: Endogenous Metabolite

D-Ribose 5-phosphate

Cat.No: T19267

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02929	ENTPD2 Protein, Human, Recombinant (aa 29-460, His) ectonucleoside triphosphate diphosphohydrolase 2,NTPDase-2,R...	Human	Baculovirus Insect Cells
	NTPDase 2, also known as ENTPD2, belongs to the ecto-nucleoside triphosphate diphosphohydrolase family (E-NTPDase). Members of E-NTPDase family are nucleotidases able to hydrolyze 5′-nucleoside tri- and/or diphosphates; the main role of these enzymes is the termination of purinergic signaling. NTPDases are ubiquitous and were previously shown in other parasites including the trypanosomatides of genus Leishmania and in T. brucei. NTPase activity would act as a timer and is crucial to T. gondii in...
TMPH-00658	NAD(P)H-flavin reductase Protein, E. coli, Recombinant (His) Riboflavin reductase [NAD(P)H],Ferrisiderophore reductase C,...	E. coli	E. coli
	Catalyzes the reduction of soluble flavins by reduced pyridine nucleotides.
TMPY-03617	GMPR Protein, Human, Recombinant (His) GMPR1,guanosine monophosphate reductase	Human	E. coli
	GMPR, also known as GMPR1, belongs to the IMPDH/GMPR family.This familyofenzymesincludesIMP dehydrogenaseandGMP reductase. These enzymes are involved inpurine metabolism and adopt aTIM barrelstructure. GMPR is an enzyme that catalyzes the irreversible and NADPH-dependent reductive deamination of GMP to IMP. GMPR functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
TMPJ-00725	HGPRT Protein, Human, Recombinant (His) HGPRT,Hypoxanthine-Guanine Phosphoribosyltransferase,HPRT,HG...	Human	E. coli
	Hypoxanthine-Guanine Phosphoribosyltransferase (HGPRT) has an important role in the generation of purine nucleotides through the purine salvage pathway. HPRT1 functions to salvage purines from degraded DNA to renewed purine synthesis, it acts as a catalyst in the reaction between guanine and phosphoribosyl pyrophosphate to form GMP.
TMPH-03283	CD39 Protein, Rat, Recombinant (His) ATP diphosphohydrolase,Entpd1,Nucleoside triphosphate diphos...	Rat	Baculovirus Insect Cells
	In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP. Hydrolyzes ATP and ADP equally well.
TMPH-03284	CD39 Protein, Rat, Recombinant (E. coli, His) Entpd1,ATP-DPH,Ecto-ATP diphosphohydrolase 1,CD39,Ecto-ATPas...	Rat	E. coli
	In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP. Hydrolyzes ATP and ADP equally well.
TMPH-00726	Ribokinase Protein, E. coli, Recombinant (His) Ribokinase,rbsK	E. coli	E. coli
	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
TMPH-03582	MazF Protein, S. epidermidis, Recombinant (His) Endoribonuclease MazF,mRNA interferase MazF,mazF,Toxin MazF	Staphylococcus epidermidis	E. coli
	Toxic component of a type II toxin-antitoxin (TA) system. Ribosome-independent, sequence-specific endoribonuclease that cleaves mRNA, thus inhibiting protein synthesis and inducing bacterial stasis. It cuts between the first and nucleotides of 5'-UACAU-3' in single-stranded RNA. Neutralized by coexpression with cognate antitoxin MazE. MazF Protein, S. epidermidis, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 19.0 kDa and the acce...
TMPH-01822	P2Y1 Protein, Human, Recombinant (His) P2Y purinoceptor 1,ADP receptor,Purinergic receptor,P2RY1	Human	E. coli
	Receptor for extracellular adenine nucleotides such as ADP. In platelets, binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and ultimately platelet aggregation. P2Y1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 12.4 kDa and the accession number is P47900.
TMPH-02575	PDE5A Protein, Mouse, Recombinant (His & Myc) cGMP-specific 3',5'-cyclic phosphodiesterase,Pde5a,cGMP-bind...	Mouse	E. coli
	Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5'-GMP. Specifically regulates nitric-oxide-generated cGMP. PDE5A Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 26.1 kDa and the accession number is Q8CG03.
TMPH-03565	MazF Protein, S. aureus, Recombinant (His) Toxin MazF,mRNA interferase MazF,mazF,Endoribonuclease MazF	Staphylococcus aureus	E. coli
	Toxic component of a type II toxin-antitoxin (TA) system. Ribosome-independent, sequence-specific endoribonuclease that cleaves mRNA, thus inhibiting protein synthesis and inducing bacterial stasis. It cuts between the first and nucleotides of 5'-UACAU-3' in single-stranded RNA. Neutralized by coexpression with cognate antitoxin MazE. MazF Protein, S. aureus, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 17.4 kDa and the accession...
TMPJ-00765	TDT Protein, Human, Recombinant (His) Terminal transferase,Terminal deoxynucleotidyltr,DNTT,Termin...	Human	E. coli
	Terminal deoxynucleotidyl transferase (TdT) is a highly conserved vertebrate enzyme that possesses the unique ability to catalyze the random addition of deoxynucleoside 5'-triphosphates onto the 3'-hydroxyl group of a single-stranded DNA. It plays an important role in the generation of immunoglobin and T-cell receptor diversity. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments duri...
TMPY-03122	GBP2 Protein, Human, Recombinant (His) guanylate binding protein 2,GBP2	Human	HEK293 Cells
	GBP-2 belongs to the guanylate-binding protein (GBP) family. GBPs are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP). As GTPases induced by IFN-gamma (Interferon-inducible GTPase), they are key to the protective immunity against microbial and viral pathogens. GBP-2 is a GTPase that converts GTP to GDP and GMP. It binds GTP, GDP and GMP. GBP-2 hydrolyzes GTP very efficiently. GDP rather than GMP is the major reaction product. GBP-2 is induced by interf...
TMPY-02081	PDE2A Protein, Human, Recombinant (aa 215-900, His) phosphodiesterase 2A, cGMP-stimulated,cGSPDE,PED2A4,PDE2A1,C...	Human	Baculovirus Insect Cells
	cGMP-dependent 3',5'-cyclic phosphodiesterase, also known as cyclic GMP-stimulated phosphodiesterase and PDE2A, is a peripheral membrane protein that belongs to the cyclic nucleotide phosphodiesterase family and PDE2 subfamily. Phosphodiesterases (PDEs) comprise a family of enzymes that regulate the levels of cyclic nucleotides, key second messengers that mediate a diverse array of functions. Phosphodiesterases (PDEs) modulate signaling by cyclic nucleotides in diverse processes such as cardiac ...
TMPY-05086	KIR2DL5 Protein, Human, Recombinant (hFc) KIR2DL5.1,CD158F,KIR2DL5.3,killer cell immunoglobulin like r...	Human	HEK293 Cells
	KIR2DL5A (Killer Cell Immunoglobulin Like Receptor, Two Ig Domains And Long Cytoplasmic Tail 5A) is a Protein Coding gene. The encoded protein belongs to the immunoglobulin superfamily. The most recently described member of the KIR family, KIR2DL5, is represented in human populations by at least four gene variants, whose exons differ by two to eight nucleotides. KIR2DL5 (CD158f) is the most recently identified inhibitory member of human killer-cell Ig-like receptors (KIRs), which enable NK cells...
TMPJ-01308	ITPase Protein, Human, Recombinant (His) Nucleoside-Triphosphate Diphosphatase,Nucleoside-Triphosphat...	Human	E. coli
	Inosine Triphosphate Pyrophosphatase (ITPase) is a cytoplasmic enzyme that belongs to the HAM1 NTPase family. ITPase hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP) and deoxyinosine triphosphate (dITP) to the monophosphate nucleotide (IMP) and diphosphate. The ITPase enzyme acts as a homodimer and does not distinguish between the deoxy- and ribose forms. ITPase probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation...
TMPY-02552	Adenylosuccinate Lyase Protein, Human, Recombinant (His) ASL,adenylosuccinate lyase,ASASE,AMPS	Human	E. coli
	Adenylosuccinate lyase, also known as adenylosuccinase, ADSL or ASL, is an enzyme implicated in the reaction of adenylosuccinat converting to AMP and fumarate as part of the purine nucleotide cycle. The two substates of adenylosuccinate lyase (ADSL) are dephosphorylated derivatives of SAICA ribotide (SAICAR) and adenylosuccinate (S-AMP), which catalyzes an important reaction in the de novo pathway of purine biosynthesis. ADSL catalyzes two distinct reactions in the synthesis of purine nucleotide...
TMPY-03180	Ribonuclease A Protein, Human, Recombinant (His) RNS1,ribonuclease, RNase A family, 1 (pancreatic),RIB1,RAC1	Human	HEK293 Cells
	RNase A, also known as ribonuclease A and RNASE1, belongs to ribonuclease A superfamily. It is a pancreatic-type of secretory ribonuclease. RNase A is a basic protein and its many positive charges are consistent with its binding to RNA (a poly-anion). More generally, RNase A is unusually polar or, rather, unusually lacking in hydrophobic groups, especially aliphatic ones. As an endonuclease, RNase A cleaves internal phosphodiester RNA bonds on the 3'-side of pyrimidine bases. It prefers poly(C) ...
TMPY-03849	NUDT5 Protein, Human, Recombinant (His) hYSAH1,YSAH1,nudix (nucleoside diphosphate linked moiety X)-...	Human	E. coli
	NUDT5 (Nudix Hydrolase 5) is a Protein Coding gene. This gene belongs to the Nudix (nucleoside diphosphate linked moiety X) hydrolase superfamily. The encoded enzyme catalyzes the hydrolysis of modified nucleoside diphosphates. ADP-sugar Pyrophosphatase, also known as NUDT5, eliminates toxic nucleotide derivatives from the cell and regulates the levels of important signaling nucleotides and their metabolites. It is widely expressed in the liver, skin, and other tissues. NUDT5 functions as a MutT...
TMPJ-01404	TMX2 Protein, Human, Recombinant (His) Cell proliferation-inducing gene 26 protein,TMX2,Thioredoxin...	Human	E. coli
	TMX2 is a single-pass type I membrane protein and contains 1 thioredoxin domain. Thioredoxin plays an important role in various cellular processes through redox regulation. The Molecular Cloning and characterization of one member of the thioredoxin superfamily, designated as TMX2.The TMX2 cDNA consists of 1644 nucleotides and contains an open reading frame encoding a protein of 372 amino acids with a predicted molecular mass of 42.5 kDa and an isoelectric point of 8.94. The TMX2 protein may pos...
TMPY-01661	METTL1 Protein, Human, Recombinant (His) methyltransferase like 1,TRMT8,TRM8,YDL201w,C12orf1	Human	E. coli
	tRNA (guanine-N(7)-)-methyltransferase, also known as Methyltransferase-like protein 1, tRNA (m7G46)-methyltransferase and METTL1, is a nucleus protein that belongs to the methyltransferase superfamily and TrmB family. METTL1 gene has been identified by its sequence similarity to the yeast ORF YDL21w. The human cDNA and the genomic structure of METTL1 have been analyzed. The transcript contains 1292 nucleotides and codes for a protein of 276 amino acids. The METTL1 gene product shows high sequen...
TMPY-02880	ENPP5 Protein, Human, Recombinant (His) NPP-5,ectonucleotide pyrophosphatase/phosphodiesterase 5 (pu...	Human	HEK293 Cells
	ENPP5 is a member of the nucleotide pyrophosphatase/phosphodiesterase family (NPP). It is a family comprised of dimeric enzymes that catalyze the hydrolysis of phosphate diester bonds. There are seven isoforms in NPP family, some of which prefer nucleotide substrates, some of which prefer phospholipid substrates, and others of which prefer substrates that have not yet been determined. NPP also belongs to the alkaline phosphatase (AP) superfamily of enzymes and they are located in the cell membra...

重组蛋白

ENTPD2 Protein, Human, Recombinant (aa 29-460, His)

Cat.No: TMPY-02929

Species: Human

Expression System: Baculovirus Insect Cells

NAD(P)H-flavin reductase Protein, E. coli, Recombinant (His)

Cat.No: TMPH-00658

Species: E. coli

Expression System: E. coli

GMPR Protein, Human, Recombinant (His)

Cat.No: TMPY-03617

Species: Human

Expression System: E. coli

HGPRT Protein, Human, Recombinant (His)

Cat.No: TMPJ-00725

Species: Human

Expression System: E. coli

CD39 Protein, Rat, Recombinant (His)

Cat.No: TMPH-03283

Species: Rat

Expression System: Baculovirus Insect Cells

CD39 Protein, Rat, Recombinant (E. coli, His)

Cat.No: TMPH-03284

Species: Rat

Expression System: E. coli

Ribokinase Protein, E. coli, Recombinant (His)

Cat.No: TMPH-00726

Species: E. coli

Expression System: E. coli

MazF Protein, S. epidermidis, Recombinant (His)

Cat.No: TMPH-03582

Species: Staphylococcus epidermidis

Expression System: E. coli

P2Y1 Protein, Human, Recombinant (His)

Cat.No: TMPH-01822

Species: Human

Expression System: E. coli

PDE5A Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02575

Species: Mouse

Expression System: E. coli

MazF Protein, S. aureus, Recombinant (His)

Cat.No: TMPH-03565

Species: Staphylococcus aureus

Expression System: E. coli

TDT Protein, Human, Recombinant (His)

Cat.No: TMPJ-00765

Species: Human

Expression System: E. coli

GBP2 Protein, Human, Recombinant (His)

Cat.No: TMPY-03122

Species: Human

Expression System: HEK293 Cells

PDE2A Protein, Human, Recombinant (aa 215-900, His)

Cat.No: TMPY-02081

Species: Human

Expression System: Baculovirus Insect Cells

KIR2DL5 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-05086

Species: Human

Expression System: HEK293 Cells

ITPase Protein, Human, Recombinant (His)

Cat.No: TMPJ-01308

Species: Human

Expression System: E. coli

Adenylosuccinate Lyase Protein, Human, Recombinant (His)

Cat.No: TMPY-02552

Species: Human

Expression System: E. coli

Ribonuclease A Protein, Human, Recombinant (His)

Cat.No: TMPY-03180

Species: Human

Expression System: HEK293 Cells

NUDT5 Protein, Human, Recombinant (His)

Cat.No: TMPY-03849

Species: Human

Expression System: E. coli

TMX2 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01404

Species: Human

Expression System: E. coli

METTL1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01661

Species: Human

Expression System: E. coli

ENPP5 Protein, Human, Recombinant (His)

Cat.No: TMPY-02880

Species: Human

Expression System: HEK293 Cells

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