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Targets Recommended: Apoptosis PI3K S1P Receptor

40

抑制剂 & 化合物

4

天然产物

14

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T8461 SKI V

Apoptosis; PI3K; S1P Receptor Apoptosis; GPCR/G Protein; PI3K/Akt/mTOR signaling
SKI V 是一种非竞争性非脂质鞘氨醇激酶抑制剂,对 GST-hSK 的IC50为 2 μM。 它减少有丝分裂的第二信使鞘氨醇-1-磷酸的形成,可诱导细胞凋亡并具有抗肿瘤活性。它还抑制PI3K,对 hPI3k 的IC50为 6 μM。
T41324 L319

Di((Z)-Non-2-en-1-yl) 9-((4-(dimethylamino)butanoyl)oxy)heptadecanedioate

Others Others
L319 (Di((Z)-Non-2-en-1-yl) 9-((4-(dimethylamino)butanoyl)oxy)heptadecanedioate) 是一种脂质膜,是一种潜在的核酸载体。
T19080 DOPE

1,2-二油酰-SN-甘油-3-磷酰乙醇胺

Others Others
DOPE (DOPE) 是一种阳离子脂质体的中性辅助脂质 (helper lipid),能够与阳离子磷脂结合,增强裸 siRNA 的转染效率。
T37184 CX08005

2-[(2-tetradecoxyphenyl)carbamoyl]benzoic acid

Phosphatase Metabolism
CX08005 是一种蛋白酪氨酸磷酸酶 1B 抑制剂,可减轻与非酒精性脂肪肝相关的肝脏脂质蓄积和微循环障碍。
T22812 GRI977143

GRI 977143

LPA Receptor GPCR/G Protein
GRI977143 是 LPA2 的选择性非脂质激动剂 (EC50 = 3.3 μM)。 GRI977143 抑制半胱天冬酶 3、7、8 和 9 的激活,并减少 DNA 片段化。
T68163 Timcodar

Antibacterial Microbiology/Virology
timcodar 是一种非 FKBP12 结合大环内酯衍生物,是外排泵抑制剂,具有抗菌活性,抑制脂质积累,抑制结核杆菌,可用于研究肥胖。
T14933 Cetaben

Others Others
Cetaben 是不依赖 PPARα 的过氧化物酶体增殖物。它可有效降低胆固醇和甘油三酸酯的浓度,是一种非纤维化降血脂药。
T28978 Tirilazad mesylate

U-74006 mesylate,U74006 mesylate,U 74006 mesylate,U 74006F mesylate,U-74006F mesylate,U74006F mesylate

Antiviral Immunology/Inflammation
Tirilazad mesylate (U 74006F) 是一种非糖皮质激素,是一种脂质过氧化抑制剂,具有抗病毒活性和神经保护活性。Tirilazad mesylate 能使细胞膜内病灶局限化,可减轻创伤、中风、缺血再灌注损伤引起的脊髓损伤,抑制狗体内毒素的作用,降低了内毒素诱导的肠系膜和肾脏 DO2 比容升高。Tirilazad mesylate 可用于研究神经系统疾病。
T4313 Tinoridine hydrochloride

盐酸替诺立定,Nonflamin,Y-3642 hydrochloride

COX; Glutathione Peroxidase Immunology/Inflammation; Metabolism; Neuroscience
Tinoridine hydrochloride (Y-3642 hydrochloride) 是非甾体抗炎药,具有显著的自由基清除和抗过氧化物特性。
T14775 Bragsin2

6-methoxy-5-nitro-2-(trifluoromethyl)chromen-4-one,Bragsin 2

Others Others
Bragsin2 (6-methoxy-5-nitro-2-(trifluoromethyl)chromen-4-one) 是非竞争性的核苷酸交换因子 BRAG2选择性抑制剂,其 IC50值为 3 μM。它能够结合到 BRAG2 的 PH 结构域和磷脂双分子层的界面处,使 BRAG2 无法激活磷脂化的 Arf GTPase。它能够影响乳腺癌干细胞。
T8902 DOTMA

Trimethyl[2,3-(dioleyloxy)propyl]ammonium Chloride,N-(1-(2,3-dioleyloxy)propyl)-N,N,N-trimethylammonium

Others Others
DOTMA (N-(1-(2,3-dioleyloxy)propyl)-N,N,N-trimethylammonium) 作为 tetra-methylated DOTA 类似物,是一种阳离子脂类,被用作基因治疗的非病毒载体。它已被用作脂质体的成分,可用于封装 siRNA、microRNA 和寡核苷酸,并用于体外基因转染。在体外和体内均表现出良好的基因转染效果。DOTMA 诱导脂质体上的正电荷,从而促进脂质体与细胞膜的有效相互作用。
T22070 DBIBB

LPA Receptor GPCR/G Protein
DBIBB 是一种特异性溶血磷脂酸 (LPA2) 的 2 型 G 蛋白偶联受体的非脂质激动剂,是一种能够治疗高强度γ 射线对造血和胃肠系统引起的急性放射综合征的潜在活性分子 ,是一种作未有机合成和药物研究中的中间体。 DBIBB 可用于制备各种化合物,可减轻胃肠道辐射综合征,增加肠隐窝存活率和肠细胞增殖,并减少细胞凋亡 。
T25885 NSC12404

CID 224134,CID224134,CID-224134,NSC 12404,NSC-12404

Others Others
NSC-12404 is a selective non-lipid LPA2/3 agonist.
T74238 BGTC

Others Others
BGTC 是一种非氨基酸阳离子脂质。BGTC 可用于核酸递送。
T74445 ZA3-Ep10

Others Others
ZA3-Ep10是一种两性离子的脂质,用于合成脂质纳米颗粒,用于体内 RNA 传递和非病毒 CRISPR/Cas 基因编辑。
T74313 MVL5

Others Others
MVL5 是一种不可降解的多价阳离子脂质。MVL5 是一种高效的 DNA 和 siRNA 载体。
T35801 ML-262

Others Others
ML-262 is an inhibitor of hepatic lipid droplet formation (IC50 = 6.4 nM in murine AML-12 cells), which is associated with non-alcoholic fatty liver disease. ML-262 does not induce cytotoxicity (up to 33 μM) or inhibit fatty acid uptake (up to 50 μM).
T62029 ML261

Others Others
ML261 是肝脂滴形成的抑制剂,IC50值为 69.7 nM。ML261 在非酒精性脂肪性肝病 (NAFLD) 和炎症中具有研究价值。
T35462 (±)11-HETE

Others Others
(±)11-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid . The individual R and S isomers of racemic HETEs have been separated and identified using chiral phase HPLC. The racemic HETEs have been quantified as an index of lipid peroxidation using GC/MS.
T36558 (±)9-HETE

Others Others
(±)9-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid. The individual R and S isomers of racemic HETEs have been separated and identified using chiral phase HPLC. The racemic HETEs have been quantified as an index of lipid peroxidation using GC/MS.
T37255 12-methyl Myristic Acid methyl ester

Others Others
12-methyl Myristic acid methyl ester is a methylated fatty acid methyl ester that has been found in vermicomposts of cattle manure, carica papaya leaves, and cuticular wax of K. africana. It is a volatile compound in lipid-lowering granulated tea. Levels of 12-methyl myristic acid methyl ester are decreased in T. cruzi treated with nifurtimox compared to non-treated controls.
T84398 8,12-iso-iPF2α-VI

12-iso-5,6E,14Z-PGF2α,12-iso-5,6E,14Z-Prostaglandin F2α,8,12-iso-Isoprostane-F2α-VI

Others Others
8,12-iso-iPF2α-VI, an isoprostane, arises from non-enzymatic, free radical-induced peroxidation of membrane lipids. It is the predominant isoprostane formed during lipid peroxidation and serves as a biomarker for oxidative stress. Detectable in hepatic tissue post CCl4-induced oxidative damage, 8,12-iso-iPF2α-VI levels are also elevated in the urine, blood, and cerebrospinal fluid of Alzheimer’s disease patients.
T78658 Pemvidutide TFA

Others Others
Pemvidutide (TFA) 是一款针对GLP-1R/GCGR的双重激动剂,有助于显著降低体重、肝脏脂肪以及血清脂质水平。该化合物主要适用于非酒精性脂肪性肝炎(NASH)和肥胖症的研究领域。
T85061 1-Palmitoyl-2-12-PAHSA-3-Oleoyl-sn-glycerol

TG(16:0/12-PAHSA/18:1),​16:0-12-PAHSA-18:1-TG

Others Others
1-Palmitoyl-2-12-PAHSA-3-oleoyl-sn-glycerol, an endogenous triacylglycerol, comprises palmitic acid (at the sn-1 position), the fatty acid ester of hydroxy fatty acids (FAHFA), 12-PAHSA (at the sn-2 position), and oleic acid (at the sn-3 position). Identified in the lipid extract of mouse adipose tissue, this triacylglycerol demonstrates that levels of FAHFA-containing triacylglycerols are over 100-fold higher than those of non-esterified FAHFAs, suggesting their role as intracellular storage re...
T78071 3-Methylglutaconic acid

β-Methylglutaconic acid

GABA Receptor Membrane transporter/Ion channel; Neuroscience
3-Methylglutaconic acid 是MGTA (3-甲基戊二酸尿症) 的主要积累代谢物,能够诱发脂质和蛋白质的氧化损伤,减弱大脑皮层上清液的非酶促抗氧化防御,导致氧化应激。此化合物适用于研究大脑损伤相关疾病。
T38296 Alamethicin F50

Alamethicin F50

Others Others
Alamethicin F50 is a peptaibol isolated from Trichoderma. It is a polymer of 20 amino acids that includes modified and non-proteinogenic amino acids. Alamethicin F50 is a mixture of 13 different peptides, with the most abundant designated as alamethicin F50/5. Alamethicin F50 forms voltage-dependent ion channels in lipid membranes and acts as a lytic agent. It induces lysis of leukocytes (IC50 = 54 and 80 μM for rat mast cells and mouse spleen lymphocytes, respectively) and exhibits antibacteria...
T79783 NSC 48160

Apoptosis Apoptosis
NSC 48160对胰腺癌细胞具有抑制作用,IC50分别针对CPFAC-1为84.3μM,对BxPC-3为94.5μM。此外,NSC 48160能够诱导胰腺癌细胞(apoptosis)。该化合物亦能改善代谢综合征症状,包括NASH、肥胖及脂质代谢紊乱。
T64297 Triton X-100

Others Others
Triton X-100 是一种溶解脂膜的非变性洗涤剂。Triton X-100 通常用于实验室,并在生产过程的不同阶段应用于疫苗。Triton X-100 被列为某些疫苗,包括裂解病毒流感疫苗的赋形剂。Triton X-100 是一种非离子表面活性剂。
T68485 Apilimod HCl

Others Others
Apilimod dimesylate is a potent and selective PIKfyve inhibitor. It exhibits no significant activity at other lipid kinases and protein kinases, including PIP4K, PIP5K, mTOR, PI3K and PI4K. Apilimod dimesylate inhibits cellular entry by SARS-CoV-2, MERS-CoV and MHV S pseudovirions. It reduces the number of SARS-CoV-2-infected hiPSC-derived pneumocyte-like cells by 85% and inhibits SARS-CoV-2 replication in donor lung tissue. It also exhibits selective cytotoxicity in B-cell non-Hodgkin lymphoma ...
T74553 YSK 05

Others Others
YSK 05是一种对pH敏感的阳离子脂质,能够改善非病毒载体的胞内转运效率。YSK 05-MEND显示出显著的基因沉默活性和溶血性。通过聚乙二醇化处理,YSK 05有效克服了对内体逃逸的抑制,从而在体外和体内均显著增强了siRNA的传递效率。
T84593 2,3-dinor-8-iso Prostaglandin F2α

2,3-dinor-iPF2α-III

Others Others
8-isoProstaglandin F2α (8-isoPGF2α; 8-isoprostane) is a byproduct of non-specific lipid peroxidation, resembling prostaglandin in structure. In humans and rats, its metabolite, 12,3-dinor-8-isoPGF2α, is formed following exogenous administration of 8-isoPGF2α, which is converted to 2,3-dinor-8-isoPGF1α and 2,3-dinor-8-isoPGF2α. Additionally, rat hepatocytes can further break down 8-isoPGF2α into a β-oxidation product, 2,3,4,5-tetranor-8-isoPGF2α. The metabolite, 2,3-dinor-8-isoPGF2α, is normally ...
T62052 AMPK activator 6

Others Others
AMPK activator 6 (Compound GC) 可降低 HepG2 和 3T3-L1 细胞中的脂质含量并激活AMPK 通路。AMPK activator 6 对血清中甘油三酯 (TG)、总胆固醇 (TC)、低密度脂蛋白-C (LDL-C) 和其他生化指标的增加有显著的抑制作用。AMPK activator 6 在非酒精性脂肪肝(NAFLD)和代谢综合征中有研究价值。
T37606 Resolvin D5

7(S),17(S)-diHDHA

Others Others
Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid and docosahexaenoic acid . [1] In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response back to a non-inflamed state.[2] Resolvin D5 (RvD5) is a DHA-derived resolvin generated by a double dioxygenation mechanism.[3] RvD5 has been identified in media from ionophore-stimulated trout brain cells, in human synovial fluid from patients with rheumatoid arthritis, and in...
T85305 Fasnall benzenesulfonate

Others Others
Fasnall, a fatty acid synthase (FASN) inhibitor, exhibits an IC50 of 3.71 μM against the human recombinant enzyme. It halts tritiated acetate incorporation into lipids (IC50= 5.84 μM), boosts ceramide levels, and triggers lipid droplet formation in BT474 HER2+ breast cancer cells. Demonstrating antiproliferative effects on various breast cancer cell lines, including non-tumorigenic MCF-10A and tumorigenic MCF-7, MDA-MB-468, BT474, and SK-BR-3, its efficacy is directly linked to FASN expression i...
T36166 8-iso-15-keto Prostaglandin F2α

8-iso-15-keto Prostaglandin F2α

Others Others
8-iso-15-keto Prostaglandin F2α (8-iso-15-keto PGF2α) is a metabolite of the isoprostane 8-iso PGF2α in rabbits, monkeys, and humans. 8-isoprostane (8-iso PGF2α) is a prostaglandin-like product of non-specific lipid peroxidation. In both humans and monkeys, exogenously infused 8-iso PGF2α is converted primarily to metabolites having 2 or 4 carbon atoms removed from the top side chain by β-oxidation. A similar pattern is observed when tritiated 8-iso PGF2α is infused into rabbits. Early in the in...
T36165 8-iso-13,14-dihydro-15-keto Prostaglandin F2α

8-iso-13,14-dihydro-15-keto Prostaglandin F2α

Others Others
8-iso-13,14-dihydro-15-keto Prostaglandin F2α (8-iso-13,14-dihydro-15-keto PGF2α) is a metabolite of the isoprostane, 8-isoprostane (8-iso PGF2α), in rabbits, monkeys and humans. 8-iso PGF2α is a PG-like product of non-specific lipid peroxidation. In both humans and monkeys, exogenously infused 8-isoprostane is converted primarily to metabolites having 2 or 4 carbon atoms removed from the top side chain by β-oxidation. A similar pattern is observed when tritiated 8-isoprostane is infused into ra...
T35946 17(R)-Resolvin D1

Aspirin-triggered Resolvin D1,17(R)-Resolvin D1

Others Others
Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid and docosahexaenoic acid.[1] In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response back to a non-inflamed state.[2] Resolvin D1 is produced physiologically from the sequential oxygenation of DHA by 15- and 5-lipoxygenase.[1] 17(R)-RvD1 is an aspirin-triggered epimer of RvD1 that reduces human polymorphonuclear leukocyte (PMN) transendothelial migration, the ear...
T35881 Resolvin E2

Others Others
Resolvin E2 (RvE2) is a member of the specialized pro-resolving mediator (SPM) family of bioactive lipids.1It is produced from eicosapentaenoic acidviaan 18-HEPE intermediate, which is formed by aspirin-acetylated COX-2-mediated oxidation of EPA, by 5-lipoxygenase (5-LO) in human polymorphonuclear (PMN) neutrophils.2,3RvE2 (20 ng/animal) inhibits increases in inflammatory exudate neutrophil infiltration in a mouse model of peritonitis induced by zymosan A .3Hepatic RvE2 levels are increased in m...
T35799 MBX-8025 (sodium salt)

Others Others
MBX-8025 is an agonist of peroxisome proliferator-activated receptor δ (PPARδ).1 It is greater than 750- and 2,500-fold selective for PPARδ over PPARα and PPARγ. MBX-8025 (10 mg/kg per day for eight weeks) reduces increases in fasting blood glucose and serum insulin levels, and decreases insulin resistance in Alms1 mutant (foz/foz) mice fed an atherogenic diet as a model of diet-induced obesity, type 2 diabetes, and non-alcoholic steatohepatitis (NASH).2 It also decreases serum alanine transamin...
T37018 OH-Chol

Others Others
OH-Chol is a cationic cholesterol derivative.1 OH-Chol, as a component of lipoplexes with DOPE , has been used for siRNA delivery and gene silencing in MCF-7 cells, as well as in mice via intravenous injection, resulting in lipoplex accumulation in the liver. It has also been used in cationic nanoparticles in combination with Tween 80 to transfect pDNA and siRNA into PC3 mouse xenografts via intratumoral injection and with Tween 80 and folate-PEG2000-DSPE in a KB mouse xenograft model for intrat...

化合物

SKI V
Cat.No: T8461
Synonym:
Target: Apoptosis, PI3K, S1P Receptor
L319
Cat.No: T41324
Synonym: Di((Z)-Non-2-en-1-yl) 9-((4-(dimethylamino)butanoyl)oxy)heptadecanedioate
Target: Others
DOPE
Cat.No: T19080
Synonym: 1,2-二油酰-SN-甘油-3-磷酰乙醇胺
Target: Others
CX08005
Cat.No: T37184
Synonym: 2-[(2-tetradecoxyphenyl)carbamoyl]benzoic acid
Target: Phosphatase
GRI977143
Cat.No: T22812
Synonym: GRI 977143
Target: LPA Receptor
Timcodar
Cat.No: T68163
Synonym:
Target: Antibacterial
Cetaben
Cat.No: T14933
Synonym:
Target: Others
Tirilazad mesylate
Cat.No: T28978
Synonym: U-74006 mesylate,U74006 mesylate,U 74006 mesylate,U 74006F mesylate,U-74006F mesylate,U74006F mesylate
Target: Antiviral
Tinoridine hydrochloride
Cat.No: T4313
Synonym: 盐酸替诺立定,Nonflamin,Y-3642 hydrochloride
Target: COX, Glutathione Peroxidase
Bragsin2
Cat.No: T14775
Synonym: 6-methoxy-5-nitro-2-(trifluoromethyl)chromen-4-one,Bragsin 2
Target: Others
DOTMA
Cat.No: T8902
Synonym: Trimethyl[2,3-(dioleyloxy)propyl]ammonium Chloride,N-(1-(2,3-dioleyloxy)propyl)-N,N,N-trimethylammonium
Target: Others
DBIBB
Cat.No: T22070
Synonym:
Target: LPA Receptor
NSC12404
Cat.No: T25885
Synonym: CID 224134,CID224134,CID-224134,NSC 12404,NSC-12404
Target: Others
BGTC
Cat.No: T74238
Synonym:
Target: Others
ZA3-Ep10
Cat.No: T74445
Synonym:
Target: Others
MVL5
Cat.No: T74313
Synonym:
Target: Others
ML-262
Cat.No: T35801
Synonym:
Target: Others
ML261
Cat.No: T62029
Synonym:
Target: Others
(±)11-HETE
Cat.No: T35462
Synonym:
Target: Others
(±)9-HETE
Cat.No: T36558
Synonym:
Target: Others
12-methyl Myristic Acid methyl ester
Cat.No: T37255
Synonym:
Target: Others
8,12-iso-iPF2α-VI
Cat.No: T84398
Synonym: 12-iso-5,6E,14Z-PGF2α,12-iso-5,6E,14Z-Prostaglandin F2α,8,12-iso-Isoprostane-F2α-VI
Target: Others
Pemvidutide TFA
Cat.No: T78658
Synonym:
Target: Others
1-Palmitoyl-2-12-PAHSA-3-Oleoyl-sn-glycerol
Cat.No: T85061
Synonym: TG(16:0/12-PAHSA/18:1),​16:0-12-PAHSA-18:1-TG
Target: Others
3-Methylglutaconic acid
Cat.No: T78071
Synonym: β-Methylglutaconic acid
Target: GABA Receptor
Alamethicin F50
Cat.No: T38296
Synonym: Alamethicin F50
Target: Others
NSC 48160
Cat.No: T79783
Synonym:
Target: Apoptosis
Triton X-100
Cat.No: T64297
Synonym:
Target: Others
Apilimod HCl
Cat.No: T68485
Synonym:
Target: Others
YSK 05
Cat.No: T74553
Synonym:
Target: Others
2,3-dinor-8-iso Prostaglandin F2α
Cat.No: T84593
Synonym: 2,3-dinor-iPF2α-III
Target: Others
AMPK activator 6
Cat.No: T62052
Synonym:
Target: Others
Resolvin D5
Cat.No: T37606
Synonym: 7(S),17(S)-diHDHA
Target: Others
Fasnall benzenesulfonate
Cat.No: T85305
Synonym:
Target: Others
8-iso-15-keto Prostaglandin F2α
Cat.No: T36166
Synonym: 8-iso-15-keto Prostaglandin F2α
Target: Others
8-iso-13,14-dihydro-15-keto Prostaglandin F2α
Cat.No: T36165
Synonym: 8-iso-13,14-dihydro-15-keto Prostaglandin F2α
Target: Others
17(R)-Resolvin D1
Cat.No: T35946
Synonym: Aspirin-triggered Resolvin D1,17(R)-Resolvin D1
Target: Others
Resolvin E2
Cat.No: T35881
Synonym:
Target: Others
MBX-8025 (sodium salt)
Cat.No: T35799
Synonym:
Target: Others
OH-Chol
Cat.No: T37018
Synonym:
Target: Others
Cat. No. Product Name Target Signaling Pathways
T19161 7α-Hydroxycholesterol

Others Others
7α-Hydroxycholesterol 是一种由酶促氧化和非酶促氧化形成的胆固醇氧化物,可用作脂质过氧化的生物标志物。
T37526 2-Oleoylglycerol

2-Oleoyl Glycerol,2-OG,2-Monoolein

GPR Endocrinology/Hormones; GPCR/G Protein
2-Oleoylglycerol 是一种存在于棕榈仁、葵花籽和米糠中的脂质。2-Oleoylglycerol 可当作一种 GPR119 激动剂,具有神经保护作用,可诱导胰高血糖素样肽 1 (GLP-1) 分泌。2-Oleoylglycerol 可用于非酒精性脂肪性肝炎造模。
T2163 Dihydrocapsaicin

CCRIS1589,二氢辣椒素,6,7-Dihydrocapsaicin,8-Methyl-N-vanillylnonanamide

Others; TRP/TRPV Channel Membrane transporter/Ion channel; Others
Dihydrocapsaicin (CCRIS1589) 是一种天然来源的辣椒素,是TRPV1的选择性激动剂,同时可以增加 p-Akt 水平。它可以增强低温诱导的神经保护。
T13199 Triacsin C

WS 1228A,FR 900190

Others Others
Triacsin C (WS 1228A) 来自金黄色链霉菌 (Streptomyces aureofaciens) ,是一种花生四烯酰辅酶A合成酶和非特异性长链酰辅酶A合成酶的差异抑制剂,抗动脉粥样硬化活性,抑制 ACSL 活性, 抑制 TAG 积聚成脂滴 (LD) 。Triacsin C 可用于研究轮状病毒感染和阿尔茨海默症。

天然产物

7α-Hydroxycholesterol
Cat.No: T19161
Synonym:
Target: Others
2-Oleoylglycerol
Cat.No: T37526
Synonym: 2-Oleoyl Glycerol,2-OG,2-Monoolein
Target: GPR
Dihydrocapsaicin
Cat.No: T2163
Synonym: CCRIS1589,二氢辣椒素,6,7-Dihydrocapsaicin,8-Methyl-N-vanillylnonanamide
Target: Others, TRP/TRPV Channel
Triacsin C
Cat.No: T13199
Synonym: WS 1228A,FR 900190
Target: Others
Cat. No. Product Name Species Expression System
TMPH-02450 MALD3 Protein, Malus domestica, Recombinant (His & SUMO)

Non-specific lipid-transfer protein,MALD3

Apple E. coli
Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues. MALD3 Protein, Malus domestica, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 25.1 kDa and the accession number is Q9M5X7.
TMPH-00791 NsLTP Protein, Helianthus annuus, Recombinant (His & Myc)

Non-specific lipid-transfer protein,SDI-9

Helianthus annuus E. coli
Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues. NsLTP Protein, Helianthus annuus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 16.4 kDa and the accession number is Q39950.
TMPH-03085 LTP2 Protein, Parietaria judaica, Recombinant (His & SUMO)

Allergen Par j II,Probable non-specific lipid

Parietaria judaica E. coli
Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues. LTP2 Protein, Parietaria judaica, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 27.3 kDa and the accession number is P55958.
TMPH-01780 SCP2 Protein, Human, Recombinant (GST)

Sterol carrier protein 2,Propanoyl-CoA C-acyltransferase,SCP...

Human E. coli
SCP2 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 42.4 kDa and the accession number is P22307.
TMPH-02181 CD1C Protein, Human, Recombinant (His)

T-cell surface glycoprotein CD1c,CD1C

Human E. coli
Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. CD1C Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 36.2 kDa and the accession number is P29017.
TMPY-03266 COL4A3BP Protein, Human, Recombinant (His & GST)

CERTL,GPBP,collagen, type IV, alpha 3 (Goodpasture antigen) ...

Human Baculovirus Insect Cells
COL4A3BP is a member of the StarD2 subfamily. It contains a pleckstrin homology domain at its amino terminus and a START domain towards the end of the molecule. COL4A3BP has a lipid-binding domain that mediates intracellular trafficking of ceramide in a non-vesicular manner. One isoform of COL4A3BP is also involved in ceramide intracellular transport. COL4A3BP specifically phosphorylates the N-terminal region of the non-collagenous domain of the alpha 3 chain of type IV collagen, known as t...
TMPY-02885 CD1B Protein, Human, Recombinant (hFc)

CD1,CD1A,CD1b molecule,R1,CD1B

Human HEK293 Cells
CD1B contains 1 Ig-like (immunoglobulin-like) domain and belongs to the CD1 family. CD1 family members are transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. During protein synthesis and maturation, they bind endogenous lipids that are replaced by lipid or glycolipid antigens when the proteins are internalized and pass through endosomes, before trafficking back to the cell surface. CD...
TMPY-06150 Par j 2 Protein, Parietaria judaica, Recombinant (His)

Parietaria judaica HEK293 Cells
Par j 2 is one of the major allergens of the Parietaria judaica. Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues. The major allergens from P. judaica pollen, Par j 1 and Par j 2, have amino acid sequence identity of 45% and contain eight cysteine residues involved in disulphide bonds that compact the structure.
TMPJ-00063 CD160 Protein, Human, Recombinant (hFc)

CD160 Antigen,CD160,BY55,Natural Killer Cell Receptor BY55

Human HEK293 Cells
CD160 antigen is a Lipid-anchor that exists as a disulfide-linked homomultimer. CD160 contains one Ig-like V-type domain. The human CD160 precursor is a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain. It is weakly homologous to KIR2DL4. CD160 is expressed in the spleen, peripheral blood, and small intestine. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. CD16...
TMPJ-00158 Apolipoprotein A-I/APOA1 Protein, Human, Recombinant

Apolipoprotein A-I,APOA1,Apo-AI,ApoA-I

Human E. coli
Apolipoprotein A1 (APOA1) is a secreted protein which belongs to the Apolipoprotein A1/A4/E family. APOA1 is the major protein component of high density lipoprotein (HDL) in plasma. APOA1 plays a critical role in various biological processes, such as Cholesterol metabolism, Lipid metabolism and transport, Steroid metabolism. APOA1 promotes cholesterol efflux from tissues to the liver and thus helps to clear cholesterol from arteries. Defects in this gene resulted in HDL deficiencies, including T...
TMPH-02346 Influenza A H1N1 (strain A/USA:Iowa/1943) Matrix protein 1 (His & Myc)

Matrix protein 1,M

H1N1 E. coli
Plays critical roles in virus replication, from virus entry and uncoating to assembly and budding of the virus particle. M1 binding to ribonucleocapsids (RNPs) in nucleus seems to inhibit viral transcription. Interaction of viral NEP with M1-RNP is thought to promote nuclear export of the complex, which is targeted to the virion assembly site at the apical plasma membrane in polarized epithelial cells. Interactions with NA and HA may bring M1, a non-raft-associated protein, into lipid rafts. For...
TMPY-02299 ALDH3A1 Protein, Human, Recombinant (His)

ALDHIII,aldehyde dehydrogenase 3 family, member A1,ALDH3

Human Baculovirus Insect Cells
Aldehyde dehydrogenase 3A1 (ALDH3A1) is a metabolic enzyme that catalyzes the oxidation of various aldehydes. Certain types of epithelial tissues in mammals, especially those continually exposed to environmental stress (e.g., corneal epithelium), express ALDH3A1 at high levels and its abundance in such tissues is perceived to help to maintain cellular homeostasis under conditions of oxidative stress. Metabolic as well as non-metabolic roles for ALDH3A1 have been associated with its mediated resi...
TMPY-04455 PKC iota Protein, Human, Recombinant (GST)

PKCI,nPKC-iota,protein kinase C, ι,DXS1179E,nPKC-ι,protein k...

Human Baculovirus Insect Cells
Protein kinase C iota type, also known as Atypical protein kinase C-lambda/iota, aPKC-lambda/iota and PRKCI, is a cytoplasm, membrane and nucleus protein which belongs to the protein kinase superfamily, AGC Ser/Thr protein kinase family and PKC subfamily. PRKCI contains one AGC-kinase C-terminal domain, one OPR domain, one phorbol-ester/DAG-type zinc finger and one protein kinase domain. PRKCI is predominantly expressed in lung and brain, but also expressed at lower levels in many tissues includ...
TMPH-02671 Gasdermin-D Protein, Mouse, Recombinant (His & Myc)

Gasdermin-D,Gasdermin domain-containing protein 1,Gsdmd

Mouse E. coli
Precursor of a pore-forming protein that plays a key role in host defense against pathogen infection and danger signals. This form constitutes the precursor of the pore-forming protein: upon cleavage, the released N-terminal moiety (Gasdermin-D, N-terminal) binds to membranes and forms pores, triggering pyroptosis.; Promotes pyroptosis in response to microbial infection and danger signals. Produced by the cleavage of gasdermin-D by inflammatory caspases CASP1 or CASP4/CASP11 in response to canon...

重组蛋白

MALD3 Protein, Malus domestica, Recombinant (His & SUMO)
Cat.No: TMPH-02450
Species: Apple
Expression System: E. coli
NsLTP Protein, Helianthus annuus, Recombinant (His & Myc)
Cat.No: TMPH-00791
Species: Helianthus annuus
Expression System: E. coli
LTP2 Protein, Parietaria judaica, Recombinant (His & SUMO)
Cat.No: TMPH-03085
Species: Parietaria judaica
Expression System: E. coli
SCP2 Protein, Human, Recombinant (GST)
Cat.No: TMPH-01780
Species: Human
Expression System: E. coli
CD1C Protein, Human, Recombinant (His)
Cat.No: TMPH-02181
Species: Human
Expression System: E. coli
COL4A3BP Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-03266
Species: Human
Expression System: Baculovirus Insect Cells
CD1B Protein, Human, Recombinant (hFc)
Cat.No: TMPY-02885
Species: Human
Expression System: HEK293 Cells
Par j 2 Protein, Parietaria judaica, Recombinant (His)
Cat.No: TMPY-06150
Species: Parietaria judaica
Expression System: HEK293 Cells
CD160 Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00063
Species: Human
Expression System: HEK293 Cells
Apolipoprotein A-I/APOA1 Protein, Human, Recombinant
Cat.No: TMPJ-00158
Species: Human
Expression System: E. coli
Influenza A H1N1 (strain A/USA:Iowa/1943) Matrix protein 1 (His & Myc)
Cat.No: TMPH-02346
Species: H1N1
Expression System: E. coli
ALDH3A1 Protein, Human, Recombinant (His)
Cat.No: TMPY-02299
Species: Human
Expression System: Baculovirus Insect Cells
PKC iota Protein, Human, Recombinant (GST)
Cat.No: TMPY-04455
Species: Human
Expression System: Baculovirus Insect Cells
Gasdermin-D Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02671
Species: Mouse
Expression System: E. coli
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