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Search Results for " mouth "

Targets Recommended: Dopamine Receptor

14

抑制剂 & 化合物

2

天然产物

12

重组蛋白

3

同位素标记化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T7943	Fluphenazine decanoate	Dopamine Receptor	GPCR/G Protein; Neuroscience
	Fluphenazine decanoate 是一种高度连续的多巴胺 D2受体阻滞剂，是一种长效吩噻嗪抗精神病药，用于精神分裂症的研究。
T2390	Cevimeline hydrochloride hemihydrate	AChR	Neuroscience
	Cevimeline hydrochloride hemihydrate 是乙酰胆碱的奎尼丁衍生物，也是选择性的和口服活性的毒蕈碱型M1和M3受体激动剂。它可穿过血脑屏障，刺激唾液腺分泌，用作口干症的催涎剂。
T0734	Antipyrine 安替比林,Phenazone,Phenazon	COX	Immunology/Inflammation; Neuroscience
	Antipyrine (Phenazone) 是一种退烧剂和止痛剂。它可用作氧化药物代谢的探针药物，常用于评估人类的肝氧化能力。
T0979	Dequalinium chloride Dequafungan,地喹氯铵,Danical,Decabis	Potassium Channel; PKC	Chromatin/Epigenetic; Cytoskeletal Signaling; Membrane transporter/Ion channel
	Dequalinium chloride (Decabis) 是一种apamin 敏感型的钾离子通道选择性阻断剂。
T0858	Flufenamic acid Arlef,Nichisedan,氟灭酸,氟芬那酸,Achless	Potassium Channel; Calcium Channel; Chloride channel; COX; AMPK; Parasite	Chromatin/Epigenetic; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Neuroscience; PI3K/Akt/mTOR signaling
	Flufenamic acid (Arlef) 是一种非甾体类抗炎剂，是一种邻氨基苯甲酸衍生物，具有镇痛、抗炎和解热的特性。它用于肌肉骨骼和关节疾病。
T4553	Procaine penicillin G 普鲁卡因青霉素,Duphapen,Hydracillin,Hostacillin	Antibiotic	Microbiology/Virology
	Procaine penicillin G (Duphapen) 是一种抗生素，可用于治疗多种细菌感染。具体来说，它用于梅毒、炭疽、口腔感染、肺炎、白喉、蜂窝组织炎和动物咬伤。
T20570	Labetalol Apo-Labetalol,Albetol,Trandate,Dilevalol,拉贝洛尔,Normodyne	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Labetalol (Apo-Labetalol) 是一种抗高血压药物，可用于心血管疾病的研究，如妊娠期高血压。它是一种口服具有活性的选择性 α1- 和非选择性 β-肾上腺素能受体 (adrenergic receptor) 竞争性拮抗剂。
T20188	Polynoxylin Formaldehyde, urea polymer,Gabrite,Hygromull,HSDB 7203	Others	Others
	Polynoxylin is an antiseptic. It is used for local treatment of the skin and the mouth.
T34228	Quinethazone Quinethazon,Hydromox,Aquamox,Quinethazonum,Chinethazonum	Others	Others
	Quinethazone is a thiazide diuretic used to treat hypertension. Common side effects include dizziness, dry mouth, nausea, and low potassium levels.
T73979	Tibezonium iodide	Others	Others
	Tibezonium iodide 是一种口咽部消毒剂，具有抗菌活性，可用于预防口腔感染。
T21119	Cevimeline AF-102B,西维美林,FKS 508,SNI 2011,HSDB 7286	Others	Others
	Cevimeline, a parasympathomimetic and muscarinic agonist, affects M1 and M3 receptors. Cevimeline has been shown to treat dry mouth and Sj gren's syndrome. It is also used to reduce Xerostomia symptoms and increase salivary flow in head and neck cancer survivors after radiotherapy.
T69144	Hexylcaine HCl	Others	Others
	Hexylcaine HCl also called cyclaine or osmocaine, is a short-acting local anesthetic. It acts by inhibiting sodium channel conduction. Overdose can lead to headache, tinnitus, numbness and tingling around the mouth and tongue, convulsions, inability to breathe, and decreased heart function.
T70855	Favipiravir sodium	Others	Others
	Favipiravir sodium is a selective inhibitor of viral RNA-dependent RNA polymerase with activity against many RNA viruses, influenza viruses, West Nile virus, yellow fever virus, foot-and-mouth disease virus as well as other flaviviruses, arenaviruses, bunyaviruses and alphaviruses.
T83704	A20FMDV2 TFA
	A20FMDV2是一种由口蹄疫病毒（FMDV）血清型O的VP1衣壳蛋白上的α-螺旋RGD细胞相互作用域组成的肽，能够结合到αVβ6整合素上。该化合物在表达人αVβ6的H357舌鳞状细胞癌细胞中抑制αVβ6整合素依赖的细胞粘附（IC50 = 1.2 µM）。与111indium-DTPA耦合时，A20FMDV2（20 MBq）可结合于在乳腺癌小鼠异种移植模型中内源性表达的αVβ6整合素，用于放射成像分析。

化合物

Fluphenazine decanoate

Cat.No: T7943

Target: Dopamine Receptor

Cevimeline hydrochloride hemihydrate

Cat.No: T2390

Target: AChR

Cat.No: T0734

Synonym: 安替比林,Phenazone,Phenazon

Target: COX

Dequalinium chloride

Cat.No: T0979

Synonym: Dequafungan,地喹氯铵,Danical,Decabis

Target: Potassium Channel, PKC

Flufenamic acid

Cat.No: T0858

Synonym: Arlef,Nichisedan,氟灭酸,氟芬那酸,Achless

Target: Potassium Channel, Calcium Channel, Chloride channel, COX, AMPK, Parasite

Procaine penicillin G

Cat.No: T4553

Synonym: 普鲁卡因青霉素,Duphapen,Hydracillin,Hostacillin

Target: Antibiotic

Cat.No: T20570

Synonym: Apo-Labetalol,Albetol,Trandate,Dilevalol,拉贝洛尔,Normodyne

Target: Adrenergic Receptor

Cat.No: T20188

Synonym: Formaldehyde, urea polymer,Gabrite,Hygromull,HSDB 7203

Target: Others

Cat.No: T34228

Synonym: Quinethazon,Hydromox,Aquamox,Quinethazonum,Chinethazonum

Target: Others

Tibezonium iodide

Cat.No: T73979

Target: Others

Cat.No: T21119

Synonym: AF-102B,西维美林,FKS 508,SNI 2011,HSDB 7286

Target: Others

Cat.No: T69144

Target: Others

Favipiravir sodium

Cat.No: T70855

Target: Others

Cat.No: T83704

Cat. No.	Product Name	Target	Signaling Pathways
T1285	Anethole trithione 茴三硫,Anetholtrithion	Others; AChR	Neuroscience; Others
	Anethole trithione (Anetholtrithion) 是硫杂环胆碱，是一种胆汁分泌刺激剂，可增强唾液分泌并增加 mAChR 受体，用于口干症的研究。
T1284	Megestrol acetate SC10363,醋酸甲地孕酮,BDH1298	Glucocorticoid Receptor; Estrogen/progestogen Receptor; Progesterone Receptor; HIV Protease; Autophagy	Autophagy; Endocrinology/Hormones; Microbiology/Virology; Others; Proteases/Proteasome
	Megestrol acetate (BDH1298) 是具有口服活性的合成孕激素。它还具有抗雄激素特性，可用于治疗厌食症和恶病质。

天然产物

Anethole trithione

Cat.No: T1285

Synonym: 茴三硫,Anetholtrithion

Target: Others, AChR

Megestrol acetate

Cat.No: T1284

Synonym: SC10363,醋酸甲地孕酮,BDH1298

Target: Glucocorticoid Receptor, Estrogen/progestogen Receptor, Progesterone Receptor, HIV Protease, Autophagy

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-04821	Influenza A H1N1 (A/Fort Monmouth/1/1947) Hemagglutinin/HA1 Protein (His) Harvey rat sarcoma viral oncogene homolog	H1N1	HEK293 Cells
	Influenza A H1N1 (A/Fort Monmouth/1/1947) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.1 kDa and the accession number is Q20MG8.
TMPY-04785	Influenza A H1N1 (A/Fort Monmouth/1/1947) Hemagglutinin/HA Protein (His) Harvey rat sarcoma viral oncogene homolog	H1N1	Baculovirus Insect Cells
	Influenza A H1N1 (A/Fort Monmouth/1/1947) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59.3 kDa and the accession number is Q20MG8.
TMPY-01061	FGF-10 Protein, Human, Recombinant fibroblast growth factor 10,KGF2	Human	E. coli
	Fibroblast growth factor 10 (FGF10) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF10 exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. FGF10 pla...
TMPY-06802	HSV 2 (strain 333) Glycoprotein D/gD Protein (His)	HSV2	HEK293 Cells
	Herpes simplex viruses (human herpesviruses types 1 and 2) commonly cause recurrent infection affecting the skin, mouth, lips, eyes, and genitals. Herpes simplex virus type 2 (HSV-2) infection is responsible for significant neurological morbidity, perhaps more than any other virus. Herpes simplex virus type 2–associated neurological disease may result from primary infection or reactivation of latent HSV-2. Common severe infections include encephalitis, meningitis, neonatal herpes, and, in immun...
TMPH-03158	PAD Protein, Porphyromonas gingivalis, Recombinant (His) Peptidylarginine deiminase	Porphyromonas gingivalis	E. coli
	Deiminates the guanidino group of C-terminal arginine residues on a variety of peptides, including the vasoregulatory peptide-hormone bradykinin, to yield ammonia and a citrulline residue. May promote the growth of the pathogen in the periodontal pocket by producing ammonia, ammonia having a protective effect during acidic cleaning cycles in the mouth. PAD Protein, Porphyromonas gingivalis, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weig...
TMPK-01144	Kremen-1 Protein, Human, Recombinant (hFc) Kremen protein 1,KREMEN1,KREMEN,KRM1	Human	HEK293 Cells
	KREMEN1 (KRM1) has been identified as a functional receptor for Coxsackievirus A10 (CV-A10), a causative agent of hand-foot-and-mouth disease (HFMD), which poses a great threat to infants globally. KRM1 selectively binds to the mature viral particle above the canyon of the viral protein 1 (VP1) subunit and contacts across two adjacent asymmetry units. The key residues for receptor binding are conserved among most KRM1-dependent enteroviruses, suggesting a uniform mechanism for receptor binding.
TMPK-00839	ITGB6 Protein, Human, Recombinant (His) β6,Integrin β-6,β 6,beta 6,Integrin β 6,Integrin beta-6,Inte...	Human	HEK293 Cells
	ITGB6 is known to be one of the major receptor components involved in host tropism of foot-and-mouth disease (FMD) virus in cattle. A competitive PCR technique called ARMS PCR was adapted to identify a single-nucleotide polymorphism (SNP), G29A, db SNP Id: rs109075046, in the 5' untranslated region (5'UTR) of the bovine ITGB6 gene. ITGB6 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 75.4 kDa and the accession number is ...
TMPK-01247	ITGB6 Protein, Mouse, Recombinant (His) ITGB6,Integrin β-6,Integrin beta-6	Mouse	HEK293 Cells
	ITGB6 is known to be one of the major receptor components involved in host tropism of foot-and-mouth disease (FMD) virus in cattle. A competitive PCR technique called ARMS PCR was adapted to identify a single-nucleotide polymorphism (SNP), G29A, db SNP Id: rs109075046, in the 5' untranslated region (5'UTR) of the bovine ITGB6 gene. ITGB6 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 75.7 kDa and the accession number is ...
TMPY-03851	BPIFB1 Protein, Human, Recombinant (His) LPLUNC1,BPI fold containing family B, member 1,C20orf114	Human	HEK293 Cells
	BPIFB1, also known as LPLUNC1, belongs to the BPI/LBP/Plunc superfamily, plunc family. BPIFB1 may be involved in the innate immune response to bacterial exposure in the mouth, nasal cavities, and lungs. BPIFB1 is expressed in the upper respiratory tract and oral cavity, which may function in host defence. The expression of BPIF proteins is associated with CF lung disease in humans and mice. It is unclear if this elevation of protein production, which results from phenotypic alteration of the cel...
TMPY-04144	Kremen-1 Protein, Human, Recombinant (His) KREMEN,KRM1,kringle containing transmembrane protein 1	Human	HEK293 Cells
	KREMEN1 (Kringle Containing Transmembrane Protein 1) is a Protein Coding gene. This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The cell surface molecule KREMEN1 is an entry receptor for coxsackievirus A1 (CV-A10). Whereas loss of KREMEN1 renders cells resistant to CV-A10 infection, KREMEN1 overexpression enhances CV-A10 binding to the cell surface and increases susceptibility...
TMPJ-00298	CD36 Protein, Human, Recombinant (aa 27-432, His) LGP85,Scavenger Receptor Class B Member 2,CD36,Lysosome Memb...	Human	HEK293 Cells
	Scavenger Receptor Class B Member 2 (SCARB2) is a type III multi-pass membrane glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes on all tissues and cell types so far examined. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstructio...
TMPJ-00299	LIMPII/SR-B2 Protein, Mouse, Recombinant (hFc) LIMP II,Lysosome membrane protein II,SCARB2,85 kDa lysosomal...	Mouse	HEK293 Cells
	Lysosome membrane protein II (LIMPII)，also known as SCARB2, is a type III multi-pass membrane glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes on all tissues and cell types so far examined. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junc...

重组蛋白

Influenza A H1N1 (A/Fort Monmouth/1/1947) Hemagglutinin/HA1 Protein (His)

Cat.No: TMPY-04821

Species: H1N1

Expression System: HEK293 Cells

Influenza A H1N1 (A/Fort Monmouth/1/1947) Hemagglutinin/HA Protein (His)

Cat.No: TMPY-04785

Species: H1N1

Expression System: Baculovirus Insect Cells

FGF-10 Protein, Human, Recombinant

Cat.No: TMPY-01061

Species: Human

Expression System: E. coli

HSV 2 (strain 333) Glycoprotein D/gD Protein (His)

Cat.No: TMPY-06802

Species: HSV2

Expression System: HEK293 Cells

PAD Protein, Porphyromonas gingivalis, Recombinant (His)

Cat.No: TMPH-03158

Species: Porphyromonas gingivalis

Expression System: E. coli

Kremen-1 Protein, Human, Recombinant (hFc)

Cat.No: TMPK-01144

Species: Human

Expression System: HEK293 Cells

ITGB6 Protein, Human, Recombinant (His)

Cat.No: TMPK-00839

Species: Human

Expression System: HEK293 Cells

ITGB6 Protein, Mouse, Recombinant (His)

Cat.No: TMPK-01247

Species: Mouse

Expression System: HEK293 Cells

BPIFB1 Protein, Human, Recombinant (His)

Cat.No: TMPY-03851

Species: Human

Expression System: HEK293 Cells

Kremen-1 Protein, Human, Recombinant (His)

Cat.No: TMPY-04144

Species: Human

Expression System: HEK293 Cells

CD36 Protein, Human, Recombinant (aa 27-432, His)

Cat.No: TMPJ-00298

Species: Human

Expression System: HEK293 Cells

LIMPII/SR-B2 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPJ-00299

Species: Mouse

Expression System: HEK293 Cells

Cat. No.	Product Name	Target	Signaling Pathways
TMID-0184	Antipyrine-d3
	Antipyrine-d3 是 Antipyrine 的氘代化合物。Antipyrine 的 CAS 号为 60-80-0。Antipyrine 是一种退烧剂和止痛剂。它可用作氧化药物代谢的探针药物，常用于评估人类的肝氧化能力。
TMIH-0183	Dequalinium Chloride-d4
	Dequalinium Chloride-d4 是 Dequalinium Chloride 的氘代化合物。Dequalinium Chloride 的 CAS 号为 522-51-0。Dequalinium chloride 是一种apamin敏感型的钾离子通道选择性阻断剂。
TMIJ-0025	Megestrol Acetate-d3
	Megestrol Acetate-d3 是 Megestrol Acetate 的氘代化合物。Megestrol Acetate 的 CAS 号为 595-33-5。Megestrol acetate 是具有口服活性的合成孕激素。它还具有抗雄激素特性，可用于治疗厌食症和恶病质。

同位素标记化合物

Cat.No: TMID-0184

Dequalinium Chloride-d4

Cat.No: TMIH-0183

Megestrol Acetate-d3

Cat.No: TMIJ-0025

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