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Search Results for " mast cells "
Targets Recommended: Histamine Receptor

61

抑制剂 & 化合物

18

天然产物

1

化合物库

70

重组蛋白

2

同位素标记化合物

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Cat. No. Product Name
L3300 组胺&褪黑色素化合物库

153 compounds
153 种生物活性小分子化合物,用于高通量、高内涵筛选;

化合物库

组胺&褪黑色素化合物库
Cat.No: L3300
Compounds: 153
Cat. No. Product Name Target Signaling Pathways
T0118 Mizolastine

SL 850324,咪唑司汀,咪唑斯汀

Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Mizolastine (SL 850324) 是组胺 H1 受体拮抗剂,IC50为 47 nM。它用于治疗过敏反应,如花粉热和荨麻疹等。
T2648 Pimecrolimus

SDZ-ASM 981,ASM 981,吡美莫司

Others Others
Pimecrolimus (SDZ-ASM 981) 是一种免疫亲和素配体,能与胞质受体特异性的结合。
T3148 MK-571 sodium

L-660711 (sodium salt),L-660711 sodium salt,Verlukast sodium,L-660711,MK571,MK-571 sodium salt,Propanoic acid

Leukotriene Receptor; LTR GPCR/G Protein; Immunology/Inflammation
MK-571 sodium (L-660711 sodium salt) 是一种可口服的选择性白三烯 D4受体拮抗剂,在豚鼠和人肺膜的 Ki 分别为0.22 和 2.1 nM。
T1260 Cromolyn sodium

Disodium Cromoglycate,FPL 670 (Cromolyn) Disodium,FPL-670,色甘酸钠,Sodium cromoglycate

Others; Potassium Channel; GSK-3; Calcium Channel Membrane transporter/Ion channel; Metabolism; Others; PI3K/Akt/mTOR signaling; Stem Cells
Cromolyn sodium (FPL-670) 是一种GSK-3β抑制剂,IC50为 2.0 µM,有抗过敏作用。
T8239 Cromoglicic acid

Others Others
Cromoglicic acid 可防止肥大细胞释放炎性化学物质,例如组胺。
T28972 Tiaramide hydrochloride

FK-1160,NTA-194,FK 1160,FK1160,tiaramide

Others Others
Tiaramide hydrochloride (FK-1160) 是一种抗炎药,可抑制肥大细胞释放的介质的作用,并具有直接的平滑肌松弛特性。
T1425 Pemirolast potassium

BMY 26517,TWT-8152,吡嘧司特钾

Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Pemirolast potassium (TWT-8152) 是 H1组胺受体拮抗剂和肥大细胞稳定剂,是一种具有抗过敏特性的嘧啶酮衍生物。
T3520 Setipiprant

KYTH-105,塞替匹仑,ACT-129968

GPR; Prostaglandin Receptor Endocrinology/Hormones; GPCR/G Protein; Immunology/Inflammation
Setipiprant (ACT-129968) 是一种口服的选择性 CRTH2 拮抗剂,IC50为6.0 nM。
T1639 Amlexanox

氨来呫诺,CHX3673,Amoxanox,氨来诺,AA673

IL Receptor; FGFR; Others; IκB/IKK Angiogenesis; Immunology/Inflammation; NF-κB; Others; Tyrosine Kinase/Adaptors
Amlexanox (AA673) 是一种特异性的 IKKε和 TBK1抑制剂,其 IC50=1-2 μM。
T3979 Emedastine

LY188695,依美斯汀,Emadine

Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Emedastine (LY188695) 是一种可口服的,选择性和高亲和力的组胺 H1受体拮抗剂,Ki 值为 1.3 nM。它是苯并咪唑衍生物,可用于过敏性鼻炎、过敏性皮肤疾病和过敏性结膜炎的研究。
T22879 JNJ 10191584 maleate

JNJ 10191584 maleate salt,VUF6002 maleate

Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
JNJ 10191584 maleate (VUF6002 maleate) 是一种具有口服活性的选择性 H4 受体拮抗剂 (Ki = 26 nM)。 JNJ 10191584 maleate 抑制嗜酸性粒细胞和肥大细胞的趋化性(IC50 = 530 nM 和 138 nM)。
T0173 Nylidrin hydrochloride

Buphenine HCl,布芬宁盐酸盐

Adrenergic Receptor GPCR/G Protein; Neuroscience
Nylidrin hydrochloride (Buphenine HCl) 是被动致敏大鼠腹腔肥大细胞中IgE 介导的组胺释放抑制剂,具有抗过敏的功效。它也是被动致敏的豚鼠肺切片中 IgG1 介导的组胺释放抑制剂。
T4657 WHI-P97

4-(3',5'-二溴-4-羟基苯基)氨基-6,7-二甲氧基喹唑啉

JAK Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells
WHI-P97 是一种选择性 JAK-3抑制剂,可用于预防过敏性哮喘的研究。
T1139 Salbutamol

Albuterol,沙丁胺醇,AH-3365

Adrenergic Receptor GPCR/G Protein; Neuroscience
Salbutamol (Albuterol) 是短效的 β2 肾上腺素受体激动剂,用于哮喘和慢性阻塞性肺疾病(COPD) 引发的支气管痉挛的研究。
TP1956L PKC ζ pseudosubstrate acetate

PKC ζ pseudosubstrate acetate (799764-07-1 free base)

PKC Chromatin/Epigenetic; Cytoskeletal Signaling
PKC ζ pseudosubstrate acetate 是蛋白激酶 C (PKC) ζ 的抑制剂;附着于细胞通透性触角足结构域载体肽。由 PKC ζ 假底物结构域的氨基酸 113-129 组成,通过二硫键连接到触角足结构域载体肽。 Antennapedia 肽在 4 或 37°C 时被完整细胞积极吸收,确保快速有效地吸收抑制肽。一旦进入细胞,二硫键在细胞质中被还原,导致抑制肽的释放。通过 PKC ζ 非依赖性途径诱导肥大细胞脱粒。
T26470 A1777

AA1777,AA-1777,AA 1777

Others Others
A1777, a selective 5-lipoxygenase inhibitor, reduces leukocytes proliferation without affecting the eosinophils of mast cells.
T19472 Nedocromil sodium

Nedocromil disodium salt,FPL 59002KP

Others Others
Nedocromil sodium is a pharmacologic stabilizer of mast cells, has been shown to normalize cytokine levels and attenuate cardiac remodeling.
T34796 TEI-9063

TEI9063

Others Others
TEI-9063 is a stable and highly specific prostacyclin analogue of prostacyclin receptor in mast cell tumor p-815 cells.
T11473 GSK-5498A

Others Others
GSK-5498A is a selective blocker of CARC (IC50, 1 μM). It inhibits mediator release from mast cells, and pro-inflammatory cytokine release from T-cells in a variety of species.
T70193 APC-366 HCl

Others Others
APC-366 is a selective inhibitor of the mast cell tryptase that inhibits tryptase-induced histamine release from human tonsil and lung cells.
TP1408 Peptide 401

Peptide 401 is an antimicrobial peptide (AMP) derived from the venom of bees and wasps. Peptide 401 induces mast cell degranulation, activating histamine release from peritoneal mast cells. Additionally, peptide 401 exhibits some anti-inflammatory activit
TQ0032L Rosiptor acetate

AQX-​1125,AQX ​1125,AQX​1125,AQX-1125 acetate

Others Others
Rosiptor is a potent and selective SHIP1 activator. AQX-1125 inhibits Akt phosphorylation in SHIP1-proficient but not in SHIP1-deficient cells, reduces cytokine production in splenocytes, inhibits the activation of mast cells and inhibits human leukocyte
T36713 Streptochlorin

Others Others
Streptochlorin is a bacterial metabolite originally isolated from Streptomyces sp. SF2583 that has diverse biological activities, including antiangiogenic, antiproliferative, and anti-allergic properties. It inhibits TNF-α-induced NF-κB transcriptional activity and decreases proliferation of human umbilical vein endothelial cells (HUVECs) when used at concentrations ranging from 5 to 20 μM. Streptochlorin (12 μg/ml) decreases viability of, as well as induces apoptosis and increases the productio...
T76095 Granuliberin R

Granuliberin R, 一种两栖动物来源的新型肥大细胞脱颗粒肽,可从(Rana rugosa)蛙皮肤中分离得到。作为一种十二肽,Granuliberin R能促使大鼠腹膜肥大细胞释放颗粒和组胺。
T82176 HR1

HR1是一种乳突蛋白酶,可增加人红细胞膜渗透性,并能诱导细菌细胞质膜和肥大细胞质膜透化。
T69059 Cromoglicate sodium hydrate

Others Others
Cromoglicic acid , cromolyn (USAN), cromoglycate (former BAN), or cromoglicate, is traditionally described as a mast cell stabilizer, and is commonly marketed as the sodium salt sodium cromoglicate or cromolyn sodium. This drug prevents the release of inflammatory chemicals such as histamine from mast cells. Because of their convenience (and perceived safety), leukotriene receptor antagonists have largely replaced it as the non-corticosteroid treatment of choice in the treatment of asthma. Cro...
T38127 pNPS-DHA

Others Others
pNPS-DHA is an arylamide derivative of docosahexaenoyl ethanolamide that has anti-allergic activity.1It inhibits degranulation of RBL-2H3 mast cells (IC50= 15 μM).pNPS-DHA (1,000 mg/kg) inhibits IgE-dependent passive cutaneous anaphylaxis (PCA) in mice. 1.Kim, I.-H., Kanayama, Y., Nishiwaki, H., et al.Structure-activity relationships of fish oil derivatives with anti-allergic activity in vitro and in vivoJ. Med. Chem.62(21)9576-9592(2019)
T76919 Barzolvolimab

Barzolvolimab (CDX 0159)为人源化抗KIT IgG1单克隆抗体。其特异性地抑制KIT激活,有效降低慢性诱导性荨麻疹中皮肤肥大细胞数量及疾病活动程度。
TP1946 QWF

Tripeptide substance P (SP) antagonist (IC50 = 90 μM). Also inhibits binding of SP to Mas-related GPCR (MRGPR) X2. Inhibits SP-induced IgE-independent degranulation of mast cells in vitro. Inhibits compound 48/80-induced MRGPRX2 activation and scratching
T80764 Xenopsin-Related Peptide 2

XP-2

Xenopsin-Related Peptide 2 (XP-2),作为Xenopsin在鸟类中的对应物,具有诱导分离大鼠肥大细胞释放组胺的能力,其效力与合成Bradykinin相媲美。
T84937 1,1'-Ethylidene-bis-(L-tryptophan)

Peak 97 Contaminant

Others Others
1,1'-Ethylidene-bis-(L-tryptophan) is a potential impurity in L-tryptophan commercial products, promoting EoL-3 eosinophilic leukemia cell proliferation, enhancing eosinophil cationic protein release from human peripheral blood eosinophils, and boosting IL-5 production in human T cells. At 40 µg/kg, it triggers fascia thickening, mast cell infiltration, inflammation, and fibrosis in mouse superficial adipose and panniculus carnosus tissues, serving as an eosinophilia-myalgia syndrome research mo...
T36545 Prostaglandin D2 methyl ester

Prostaglandin D2 methyl ester

Others Others
Prostaglandin D2 (PGD2) is the major eicosanoid product of mast cells and is produced in large quantities by hematopoietic PGD synthase during allergic and asthmatic anaphylaxis. It causes vasodilation, flushing, hypotension, and is an inhibitor of platelet aggregation. Prostaglandin D2 methyl ester (PGD2 methyl ester) is a more lipid-soluble, cell-permeable prodrug form of PGD2. It binds to the human and mouse PGD2 receptors (DP1 and CRTH2/DP2) with 5-10 fold lower affinity than PGD2.
T38126 PMX 53c

Others Others
Negative control for PMX 53. Active Analog also available. Subramanian et al (2011) PMX-53 as a dual CD88 antagonist and an agonist for Mas-related gene 2 (MrgX2) in human mast cells. Mol.Pharmacol. 79 1005 PMID:21441599
T70377 BAY 61-3606 HCl

Others Others
BAY 61-3606 HCl is a cell-permeable, reversible inhibitor of spleen tyrosine kinase. BAY 61-3606 HCl can inhibit degranulation and block cytokine release from mast cells. Oral administration of BAY 61-3606 to rats was shown to suppress antigen-induced passive cutaneous anaphylactic reaction, bronchoconstriction, and bronchial edema. It can also sensitize MCF-7 breast cancer cells to TNF-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis by inhibiting Cdk9. This compound has been used i...
T35453 β-Defensin-4 (human) (trifluoroacetate salt)

β-Defensin-4 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts. It induces migration of monocytes in vitro when used at a concentration of 10 nM but does not affect migration of neutrophils and eosinophils. β-Defensin-4 (30 μg/ml) stimulates gene expression and production of IL-6, IL-10, CXCL10, CCL2, MIP-3α, and RANTES by keratinocytes. It also stimulates calcium mobilization, migration, and pro...
T38834 LYP-IN-1

Others Others
LYP-IN-1 is a powerful LYP inhibitor that demonstrates high potency, selectivity, and specificity, with a Ki of 110 nM and an IC 50 of 0.259 μM. Beyond its primary target, LYP-IN-1 also exhibits selectivity towards a wide range of PTPs, including SHP1 (IC 50 = 5 μM) and SHP2 (IC 50 = 2.5 μM). Additionally, LYP-IN-1 demonstrates remarkable efficacy in T- and mast cells, making it a valuable tool for investigating autoimmune disorders.
T35452 β-Defensin-3 (human) (trifluoroacetate salt)

β-Defensin-3 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts. It inhibits the growth of the periodontopathogenic and cariogenic bacteria F. nucleatum, S. mutans, S. sobrinus, S. salivarius, and L. casei (MICs = 12.5-100 mg/l). It also inhibits the growth of S. aureus, S. pyogenes, P. aeruginosa, E. coli, and C. albicans. β-Defensin-3 stimulates gene expression and production of IL-6, IL-10, CXC...
T84605 15(R)-HETE

15(R)-Hydroxyeicosatetraenoic Acid

Others Others
15(R)-HETE, a monohydroxy fatty acid, is synthesized from arachidonic acid via aspirin-acetylated COX-2, leading to the formation of specialized pro-resolving mediators 15(R)-lipoxin A4 and B4 through a transcellular mechanism involving 5-lipoxygenase (5-LO). Additionally, this compound is produced by the cytochrome P450 (CYP) isoform CYP2C9 and can be generated from arachidonic acid by COX-1 in human mast cells, where it accumulates due to its resistance to conversion into 15-KETE by 15-hydroxy...
TP2058 Catestatin

Non-competitive nicotinic cholinergic antagonist; selectively inhibits nicotinic-stimulated catecholamine secretion from chromaffin cells and noradrenergic neurons (IC50 ~ 200 nM). Blocks nicotinic-induced cationic signaling (IC50 ~ 200 - 250 nM) and inhi
T38296 Alamethicin F50

Alamethicin F50

Others Others
Alamethicin F50 is a peptaibol isolated from Trichoderma. It is a polymer of 20 amino acids that includes modified and non-proteinogenic amino acids. Alamethicin F50 is a mixture of 13 different peptides, with the most abundant designated as alamethicin F50/5. Alamethicin F50 forms voltage-dependent ion channels in lipid membranes and acts as a lytic agent. It induces lysis of leukocytes (IC50 = 54 and 80 μM for rat mast cells and mouse spleen lymphocytes, respectively) and exhibits antibacteria...
T84646 Δ12-Prostaglandin D2

Δ12-PGD2

Others Others
Prostaglandin D2 (PGD2) is a primary enzymatic prostaglandin derived from PGH2 and is abundantly produced in the cerebrospinal fluid (CSF) by the lipocalin-type PGD synthase, and peripherally by myeloid cells such as mast cells and basophils via a hematopoietic-type PGD synthase. PGD2 is chemically unstable and presents challenges for use and analysis due to its brief in vivo half-life. Δ12-PGD2, an initial decomposition product of PGD2, acts as an intermediate in the pathway to Δ12-PGJ2, a cycl...
T37492 11-trans Leukotriene C4

11-trans Leukotriene C4

Others Others
11-trans Leukotriene C4 (11-trans LTC4) is a C-11 double bond isomer of LTC4. LTC4 undergoes slow temperature-dependent isomerization to 11-trans LTC4 during storage. 11-trans LTC4 is produced in smaller amounts relative to LTC4 in ionophore-stimulated HMC-1 cells (a human mast cell line) and equine eosinophils, but not in human neutrophils or RBL-1 cells. It is nearly equipotent with LTC4 for contraction of guinea pig parenchymal and ileum. In a radioligand binding assay using guinea pig ileum ...
TP1956 PKC ζ pseudosubstrate

Inhibitor of protein kinase C (PKC) ζ; attached to cell permeabilisation Antennapedia domain vector peptide. Consists of amino acids 113 - 129 of PKC ζ pseudosubstrate domain linked by a disulphide bridge to the Antennapedia domain vector peptide. The Antennapedia peptide is actively taken up by intact cells, at 4 or 37°C, ensuring rapid and effective uptake of the inhibitor peptide. Once inside the cell, the disulphide bonds are subjected to reduction in the cytoplasm leading to release of the ...
T37604 ITK inhibitor

Others Others
Interleukin-2-inducible T cell kinase (ITK) is a non-receptor tyrosine kinase expressed in T cells, NKT cells and mast cells which plays a crucial role in regulating the T cell receptor (TCR), CD28, CD2, chemokine receptor CXCR4, and FcepsilonR-mediated signaling pathways. ITK inhibitors can be used for the treatment of inflammation and immune-mediated disorders. ITK inhibitor (N-[5-[[3-[(4-Acetylpiperazin-1-yl)carbonyl]-4-methyl-6-methoxy-phenyl]thio]thiazol-2-yl]-4-(N-1,2-dimethylpropylaminome...
T68701 Abarelix acetate

Others Others
Abarelix acetate is a synthetic third generation gonadotropin-releasing hormone receptor (GnRHR) antagonist. It increases histamine release from rat peritoneal mast cells in vitro and from a human skin model ex vivo. In vivo, abarelix decreases plasma luteinizing hormone (LH) levels six hours post-treatment in castrated rats, with levels returning to baseline within 24 hours.3 Abarelix (2 mg/kg) also transiently decreases plasma testosterone levels in intact rats, with levels returning to baseli...
T76869 Lirentelimab

Lirentelimab (AK002) 是一种人源化IgG1单克隆抗体,目标为唾液酸结合Ig样凝集素8 (SIGLEC8)。该化合物通过诱导IL-5激活的嗜酸性粒细胞细胞凋亡并抑制IL-5介导的肥大细胞激活,用于嗜酸性胃炎、十二指肠炎的研究。
TP1910 CALP1

Cell-permeable calmodulin (CaM) agonist that binds to the EF-hand/Ca2+-binding site; produces CaM-dependent activation of phosphodiesterase. Also binds to cytoplasmic sites on other Ca2+ channels, including NMDA and HIV-1 gp120-activated channels, inhibit
T84522 14,15-Leukotriene C4

Eoxin C4

Others Others
Leukotriene C4 (14,15-LTC4) is an inflammatory mediator synthesized from arachidonic acid through the actions of 15- and 12-lipoxygenases (LOs), involving intermediates such as 15-HpETE and 14,15-LTA4. Unlike the majority of leukotrienes formed via the 5-LO pathway, 14,15-LTC4 is an eoxin predominantly produced by eosinophils, although mast cells and nasal polyps can also synthesize it. While its physiological roles are not well understood, 14,15-LTC4 exhibits limited contractile activity on gui...
T35731 Deethylindanomycin

Others Others
Deethylindanomycin is a polyether antibiotic that has been found in S. setonii. It is active against a variety of Gram-positive bacteria, including various strains of S. aureus and Streptococcus, as well as one strain of S. pneumoniae (MICs = 4, 4, and 2 μg/ml, respectively). It is also active against coccidia in vitro, inhibiting E. tenella development, but is inactive against E. tenella infection in chicks when administered at a dose of 200 μg/g in the diet. Deethylindanomycin acts as an ionop...
T78641 ER-27319

Syk Angiogenesis; Tyrosine Kinase/Adaptors
ER-27319为吖啶酮衍生物,高效选择性抑制SYK,阻断其酪氨酸磷酸化和活性。本化合物阻止抗原刺激下人及大鼠肥大细胞释放过敏介质,IC50约为10 μM,适用于过敏性疾病研究。

化合物

Mizolastine
Cat.No: T0118
Synonym: SL 850324,咪唑司汀,咪唑斯汀
Target: Histamine Receptor
Pimecrolimus
Cat.No: T2648
Synonym: SDZ-ASM 981,ASM 981,吡美莫司
Target: Others
MK-571 sodium
Cat.No: T3148
Synonym: L-660711 (sodium salt),L-660711 sodium salt,Verlukast sodium,L-660711,MK571,MK-571 sodium salt,Propanoic acid
Target: Leukotriene Receptor, LTR
Cromolyn sodium
Cat.No: T1260
Synonym: Disodium Cromoglycate,FPL 670 (Cromolyn) Disodium,FPL-670,色甘酸钠,Sodium cromoglycate
Target: Others, Potassium Channel, GSK-3, Calcium Channel
Cromoglicic acid
Cat.No: T8239
Synonym:
Target: Others
Tiaramide hydrochloride
Cat.No: T28972
Synonym: FK-1160,NTA-194,FK 1160,FK1160,tiaramide
Target: Others
Pemirolast potassium
Cat.No: T1425
Synonym: BMY 26517,TWT-8152,吡嘧司特钾
Target: Histamine Receptor
Setipiprant
Cat.No: T3520
Synonym: KYTH-105,塞替匹仑,ACT-129968
Target: GPR, Prostaglandin Receptor
Amlexanox
Cat.No: T1639
Synonym: 氨来呫诺,CHX3673,Amoxanox,氨来诺,AA673
Target: IL Receptor, FGFR, Others, IκB/IKK
Emedastine
Cat.No: T3979
Synonym: LY188695,依美斯汀,Emadine
Target: Histamine Receptor
JNJ 10191584 maleate
Cat.No: T22879
Synonym: JNJ 10191584 maleate salt,VUF6002 maleate
Target: Histamine Receptor
Nylidrin hydrochloride
Cat.No: T0173
Synonym: Buphenine HCl,布芬宁盐酸盐
Target: Adrenergic Receptor
WHI-P97
Cat.No: T4657
Synonym: 4-(3',5'-二溴-4-羟基苯基)氨基-6,7-二甲氧基喹唑啉
Target: JAK
Salbutamol
Cat.No: T1139
Synonym: Albuterol,沙丁胺醇,AH-3365
Target: Adrenergic Receptor
PKC ζ pseudosubstrate acetate
Cat.No: TP1956L
Synonym: PKC ζ pseudosubstrate acetate (799764-07-1 free base)
Target: PKC
A1777
Cat.No: T26470
Synonym: AA1777,AA-1777,AA 1777
Target: Others
Nedocromil sodium
Cat.No: T19472
Synonym: Nedocromil disodium salt,FPL 59002KP
Target: Others
TEI-9063
Cat.No: T34796
Synonym: TEI9063
Target: Others
GSK-5498A
Cat.No: T11473
Synonym:
Target: Others
APC-366 HCl
Cat.No: T70193
Synonym:
Target: Others
Peptide 401
Cat.No: TP1408
Synonym:
Target:
Rosiptor acetate
Cat.No: TQ0032L
Synonym: AQX-​1125,AQX ​1125,AQX​1125,AQX-1125 acetate
Target: Others
Streptochlorin
Cat.No: T36713
Synonym:
Target: Others
Granuliberin R
Cat.No: T76095
Synonym:
Target:
HR1
Cat.No: T82176
Synonym:
Target:
Cromoglicate sodium hydrate
Cat.No: T69059
Synonym:
Target: Others
pNPS-DHA
Cat.No: T38127
Synonym:
Target: Others
Barzolvolimab
Cat.No: T76919
Synonym:
Target:
QWF
Cat.No: TP1946
Synonym:
Target:
Xenopsin-Related Peptide 2
Cat.No: T80764
Synonym: XP-2
Target:
1,1'-Ethylidene-bis-(L-tryptophan)
Cat.No: T84937
Synonym: Peak 97 Contaminant
Target: Others
Prostaglandin D2 methyl ester
Cat.No: T36545
Synonym: Prostaglandin D2 methyl ester
Target: Others
PMX 53c
Cat.No: T38126
Synonym:
Target: Others
BAY 61-3606 HCl
Cat.No: T70377
Synonym:
Target: Others
β-Defensin-4 (human) (trifluoroacetate salt)
Cat.No: T35453
Synonym:
Target:
LYP-IN-1
Cat.No: T38834
Synonym:
Target: Others
β-Defensin-3 (human) (trifluoroacetate salt)
Cat.No: T35452
Synonym:
Target:
15(R)-HETE
Cat.No: T84605
Synonym: 15(R)-Hydroxyeicosatetraenoic Acid
Target: Others
Catestatin
Cat.No: TP2058
Synonym:
Target:
Alamethicin F50
Cat.No: T38296
Synonym: Alamethicin F50
Target: Others
Δ12-Prostaglandin D2
Cat.No: T84646
Synonym: Δ12-PGD2
Target: Others
11-trans Leukotriene C4
Cat.No: T37492
Synonym: 11-trans Leukotriene C4
Target: Others
PKC ζ pseudosubstrate
Cat.No: TP1956
Synonym:
Target:
ITK inhibitor
Cat.No: T37604
Synonym:
Target: Others
Abarelix acetate
Cat.No: T68701
Synonym:
Target: Others
Lirentelimab
Cat.No: T76869
Synonym:
Target:
CALP1
Cat.No: TP1910
Synonym:
Target:
14,15-Leukotriene C4
Cat.No: T84522
Synonym: Eoxin C4
Target: Others
Deethylindanomycin
Cat.No: T35731
Synonym:
Target: Others
ER-27319
Cat.No: T78641
Synonym:
Target: Syk
Cat. No. Product Name Target Signaling Pathways
TN6737 (25R)-Spirost-4-ene-3,12-dione

Others Others
(25R)-Spirost-4-ene-3,12-dione 是一种天然产物,抑制中性粒细胞超氧阴离子的产生和肥大细胞组胺的释放。
TN1516 Cnidicin

蛇床素,4,9-双[(3-甲基-2-丁烯-1-基)氧基]-7H-呋喃并[3,2-G][1]苯并吡喃-7-酮

NOS; NO Synthase Immunology/Inflammation
Cnidicin 是一种香豆素,对肥大细胞脱颗粒及 RAW 264.7 细胞产生一氧化氮具有抑制作用。
T6926 Palmitoylethanolamide

Mackpeart DR 14V,帕米醇,N-palmitoylethanolamine,Loramine P 256,Impulsin,AM 3112,Palmidrol

Influenza Virus; Endogenous Metabolite; PPAR DNA Damage/DNA Repair; Metabolism; Microbiology/Virology
Palmitoylethanolamide (Impulsin) 是一种内源性脂肪酸酰胺。它有消炎药、降压药、神经保护剂和抗惊厥药的作用。在给药后,Palmitoylethanolamide 可抑制促炎介质从活化肥大细胞的释放。
T4S0797 Berberine

小檗碱,Berberin,Umbellatine,黄连素

Reactive Oxygen Species; Topoisomerase; Endogenous Metabolite; Antibacterial; Antibiotic; Autophagy Autophagy; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB
Berberine (Umbellatine) 属于生物碱类天然产物,可以激活 AMPK、抑制 DNA 拓扑异构酶、诱导 ROS 生成。Berberine 具有抗肿瘤、抗菌、降血糖、降血脂等生物学活性。
T5S2343 Acetylshikonin

乙酰紫草素,Acetyl shikonin

Others; P450; AChE Metabolism; Neuroscience; Others
Acetylshikonin 来源于紫草根,具有抗癌、抗炎作用。它是一种 AChE 抑制剂,具有很强的抗凋亡活性。它是一种非选择性的细胞色素 P450抑制剂,对所有 P450 亚型抑制的 IC50值范围为 1.4-4.0 μM。
T3S0027 Picropodophyllotoxin

AXL 1717,Picropodophyllin,苦鬼臼毒素

IGF-1R Tyrosine Kinase/Adaptors
Picropodophyllotoxin (AXL 1717) 是一种环木脂素生物碱,存在于五月树(Podophyllum peltatum) 中,是一种具有潜在抗肿瘤活性的胰岛素样生长因子 1 受体 (IGF1R) 的小分子抑制剂。它特异性抑制 IGF1R 的活性并下调细胞表达,而不干扰其他生长因子受体的活性,例如胰岛素受体、表皮生长因子、血小板衍生生长因子、成纤维细胞生长因子和肥大/干细胞生长因子 (KIT) )。该药剂在抑制肿瘤细胞增殖和诱导肿瘤细胞凋亡方面显示出有效的活性。 IGF1R 是一种在多种人类癌症中过度表达的受体酪氨酸激酶,在多种癌细胞的生长和存活中起关键作用。
T80998 Thapsigargicin

Thapsigargicine

Thapsigargicin(Thapsigargicine)作为肥大细胞和白细胞的激活剂,能诱导大鼠腹膜肥大细胞及人嗜碱性粒细胞释放组胺,并提升完整人血小板中的细胞质游离钙水平。
TN3062 4'-O-Methylnyasol

Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
4'-O-Methylnyasol may have potential to be developed as medicines for the treatment of allergies by inhibiting the activation of mast cells.
TN5647 Confluentin

Confluentin has antimicrobial activity against the gram-positive bacteria.Confluentin significantly inhibits compound 48/80-induced histamine release from rat peritoneal mast cells. Confluentin also shows weak cytotoxicity against four human tumor cell li
TN6539 Pd-C-II

Pd-C-II has anti-inflammation activity, it can inhibit TNF-α production and iNOS protein expression and inhibit COX-2 protein expression in LPS-stimulated RAW 264.7 cells. Pd-C-II inhibits anaphylactic mediator release from purified mast cells induced by
TN4392 Koaburaside

IL Receptor; TNF; Influenza Virus Apoptosis; Immunology/Inflammation; Microbiology/Virology
Koaburaside exhibits antioxidant activity with an IC50 value of 9.0μM, it shows weak inhibitory activity against influenza A neuraminidase. Koaburaside may have anti-allergic inflammatory activity, it can suppress histamine release from mast cells.
TN3325 9-O-Feruloyl-5,5'-dimethoxylariciresinol

IL Receptor; TNF Apoptosis; Immunology/Inflammation
(+)-9'-O-trans-feruloyl-5,5'-dimethoxylariciresinol may have anti-allergic inflammatory effect, it can inhibit release of histamine from mast cells. It shows cytotoxicity against a small panel of human tumor cell lines, with ED50 values of 9.86 to approxi
TN6667 Spinacetin

Spinacetin has anti-inflammatory effects, it weakly inhibited nitric oxide production and reduced prostaglandin E2 levels to different extents. It shows the activities in preventing inflammatory processes, which might be at least partially attributed to t
TN1009 Epimagnolin B

NF-κB; NO Synthase; Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation; NF-κB
Epimagnolin B 是一种双环氧木质素,分离自木兰中。它能够抑制 LPS 激活的小胶质细胞中 NO 的产生。它具有抗过敏以及抗炎作用。
TN4683 Nyasol

ERK; IL Receptor; IκB/IKK; NOS; NF-κB; Akt; Antifection Cytoskeletal Signaling; Immunology/Inflammation; MAPK; Microbiology/Virology; NF-κB; PI3K/Akt/mTOR signaling
Nyasol may have potential to be developed as medicines for the treatment of allergies by inhibiting the activation of mast cells. Nyasol shows anti-inflammatory properties by inhibiting iNOS expression; it also has antifungal activity, it is significantly
TN7505 Thujopsene

NSC 44707

Others Others
Thujopsene, a sesquiterpene found in T. dolabrata, exhibits a wide range of biological activities. It inhibits Na+/K+-ATPase and cytochrome P450 (CYP) isoform CYP2B6 with IC50 values of 25.9 µg/ml and Ki of 0.8 µM, respectively. Additionally, thujopsene demonstrates antimicrobial efficacy against both Gram-positive and Gram-negative bacteria, such as S. aureus, M. luteus, and S. typhimurium, with MICs ranging from 25-50 µg/ml. It also suppresses antigen-induced β-hexosaminidase release in IgE-se...
T37272 9(S),12(S),13(S)-TriHOME

Others Others
9(S),12(S),13(S)-TriHOME is a linoleic acid-derived oxylipin that has diverse biological activities.1,2,3,4It has been found in various plants and is produced in human eosinophils in a 15-lipoxygenase-dependent, soluble epoxide hydrolase-independent manner.1,59(S),12(S)13(S)-TriHOME inhibits antigen-induced β-hexosaminidase release from RBL-2H3 mast cells (IC50= 28.7 μg/ml).2It inhibits LPS-induced nitric oxide (NO) production in BV-2 microglia (IC50= 40.95 μM).3In vivo, 9(S),12(S),13(S)-TriHOME...
T38285 C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))

C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))

Others Others
C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))是成熟髓鞘中主要的硫酸盐类化合物。C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z)) 在大鼠小脑中发现活跃的髓发生鞘化反应时积累率高于C24 3'-sulfo 半乳糖甘油酰胺。C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))与C 型凝集素和免疫球蛋白样受体相互作用使对LMIR5的亲和力高。C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))诱导嗜碱细胞产生MCP-1,可通过增加LMIR5激活NFAT,但不能诱导肥大细胞 。C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))在体外与CD1d 结合,并增加游离小鼠脾细胞的增殖。

天然产物

(25R)-Spirost-4-ene-3,12-dione
Cat.No: TN6737
Synonym:
Target: Others
Cnidicin
Cat.No: TN1516
Synonym: 蛇床素,4,9-双[(3-甲基-2-丁烯-1-基)氧基]-7H-呋喃并[3,2-G][1]苯并吡喃-7-酮
Target: NOS, NO Synthase
Palmitoylethanolamide
Cat.No: T6926
Synonym: Mackpeart DR 14V,帕米醇,N-palmitoylethanolamine,Loramine P 256,Impulsin,AM 3112,Palmidrol
Target: Influenza Virus, Endogenous Metabolite, PPAR
Berberine
Cat.No: T4S0797
Synonym: 小檗碱,Berberin,Umbellatine,黄连素
Target: Reactive Oxygen Species, Topoisomerase, Endogenous Metabolite, Antibacterial, Antibiotic, Autophagy
Acetylshikonin
Cat.No: T5S2343
Synonym: 乙酰紫草素,Acetyl shikonin
Target: Others, P450, AChE
Picropodophyllotoxin
Cat.No: T3S0027
Synonym: AXL 1717,Picropodophyllin,苦鬼臼毒素
Target: IGF-1R
Thapsigargicin
Cat.No: T80998
Synonym: Thapsigargicine
Target:
4'-O-Methylnyasol
Cat.No: TN3062
Synonym:
Target: Histamine Receptor
Confluentin
Cat.No: TN5647
Synonym:
Target:
Pd-C-II
Cat.No: TN6539
Synonym:
Target:
Koaburaside
Cat.No: TN4392
Synonym:
Target: IL Receptor, TNF, Influenza Virus
9-O-Feruloyl-5,5'-dimethoxylariciresinol
Cat.No: TN3325
Synonym:
Target: IL Receptor, TNF
Spinacetin
Cat.No: TN6667
Synonym:
Target:
Epimagnolin B
Cat.No: TN1009
Synonym:
Target: NF-κB, NO Synthase, Prostaglandin Receptor
Nyasol
Cat.No: TN4683
Synonym:
Target: ERK, IL Receptor, IκB/IKK, NOS, NF-κB, Akt, Antifection
Thujopsene
Cat.No: TN7505
Synonym: NSC 44707
Target: Others
9(S),12(S),13(S)-TriHOME
Cat.No: T37272
Synonym:
Target: Others
C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))
Cat.No: T38285
Synonym: C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))
Target: Others
Cat. No. Product Name Species Expression System
TMPJ-00051 IL-3 Protein, Mouse, Recombinant (His)

Mast cell growth factor,Il3,Multipotential colony-s...

Mouse HEK293 Cells
Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenitors. In addition, IL-3 also affects the functional activity of mature mast cells, basophils, eosinophils and macrophages.Because of its multiple functions and targets, it was originally studied under different names, including mast cell growth factor P-cell stimulating factor, bu...
TMPJ-01204 TPSAB1 Protein, Human, Recombinant (His)

TPS1,tryptase alpha/beta 1,TPS2,tryptase α/β1,tryptase α/β 1...

Human HEK293 Cells
Tryptases are serine proteases with trypsin-like specificity. Together with chymases and Cathepsin G, tryptases are important players in mast cell mediation of inflammatory and allergic responses. Tryptase alpha/beta-1(TPSAB1), also known as mast cell protease 7 (MCPT7), it exhibits anticoagulant activity due to its ability to degrade fibrinogen in the presence of a diverse array of protease inhibitors in plasma. The two Isoform 1 and isoform 2 are expressed in lung, stomach, spleen, heart and s...
TMPJ-01465 GM-CSF/CSF2 Protein, Human, Recombinant (E. coli)

Colony-Stimulating Factor,CSF2,CSF,Sargramostim,集落刺激因子,Molgr...

Human E. coli
Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by a number of different cell types (including activated T cells, B cells, macrophages, mast cells, endothelial cells and fibroblasts) in response to cytokine of immune and inflammatory stimuli. Besides granulocyte-macrophage progenitors, GM-CSF is also a growth factor for erythroid, megakaryo...
TMPJ-00042 TSLP Protein, Human, Recombinant

TSLP,Thymic stromal lymphopoietin

Human E. coli
Thymic stromal lymphopoietin (TSLP) is a novel member of the hemopoietic cytokine family that promotes the development of B cells and shares overlapping activity with IL-7. The human TSLP protein comprises a 28 amino acids (aa) signal sequence and 131 aa mature region. Human TSLP has two isoforms lfTSLP and sfTSLP produced by alternative splicing . lfTSLP is expressed in a number of tissues including heart, liver and prostate, and sfTSLP (63aa) is predominantly expressed in keratinocytes of oral...
TMPJ-00187 CD300A Protein, Human, Recombinant (hFc & His)

CMRF35-like molecule 8,NK inhibitory receptor,CMRF-35-H9,Imm...

Human HEK293 Cells
CD300A is a single-pass type I membrane protein which belongs to the CD300 family. It contains 1 Ig-like V-type (immunoglobulin-like) domain. The CD300 family of myeloid immunoglobulin receptors includes activating (CD300b, CD300e) and inhibitory members (CD300a, CD300f), as well as molecules presenting a negative charge within their transmembrane domain (CD300c, CD300d). It is expressed not only by natural killer (NK) cells but also by T-cell subsets, B-cells, dendritic cells, mast cells, granu...
TMPK-00212 CD300A Protein, Mouse, Recombinant (His)

MAIR-I,IGSF12,IRp60,Mcipr1,CLM8,NKRL,IRC1,CD300a,Pigr4,CLM-8...

Mouse HEK293 Cells
CD300a is an inhibitory receptor for mast cells and eosinophils in allergic inflammation (AI); however, the spatiotemporal expression of CD300a and its potential roles in the resolution of AI are still to be determined.CD300a expression on peritoneal cells is regulated from inflammation to resolution. CD300a activation on mouse bone marrow-derived mast cells regulated ALX/FPR2 expression levels following IgE-mediated activation. CD300A Protein, Mouse, Recombinant (His) is expressed in HEK293 mam...
TMPK-00187 CD300A Protein, Human, Recombinant (Avi), Biotinylated

Pigr4,LMIR1,IGSF12,CLM-8,CD300a,CLM8,IRC1,MAIR-I,Mcipr1,IRp6...

Human HEK293 Cells
CD300a is an inhibitory receptor for mast cells and eosinophils in allergic inflammation (AI); however, the spatiotemporal expression of CD300a and its potential roles in the resolution of AI are still to be determined.CD300a expression on peritoneal cells is regulated from inflammation to resolution. CD300a activation on mouse bone marrow-derived mast cells regulated ALX/FPR2 expression levels following IgE-mediated activation. CD300A Protein, Human, Recombinant (Avi), Biotinylated is expressed...
TMPH-02499 Allergin-1 Protein, Mouse, Recombinant (His & Myc)

Mca32,Gm885,Allergy inhibitory receptor 1,Mast cell...

Mouse E. coli
Immunoglobulin-like receptor which plays an inhibitory role in degranulation of mast cells. Negatively regulates IgE-mediated mast cell activation and suppresses the type I immediate hypersensitivity reaction. Allergin-1 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 20.1 kDa and the accession number is Q3TB92.
TMPK-00561 CD300A Protein, Cynomolgus, Recombinant (His)

Mcipr1,IGSF12,IRp60,LMIR1,CD300a,MAIR-I,Pigr4,CLM-8,IRC1,NKR...

Cynomolgus HEK293 Cells
CD300a is an inhibitory receptor for mast cells and eosinophils in allergic inflammation (AI); however, the spatiotemporal expression of CD300a and its potential roles in the resolution of AI are still to be determined.CD300a expression on peritoneal cells is regulated from inflammation to resolution. CD300a activation on mouse bone marrow-derived mast cells regulated ALX/FPR2 expression levels following IgE-mediated activation. CD300A Protein, Cynomolgus, Recombinant (His) is expressed in HEK29...
TMPK-00560 CD300A Protein, Cynomolgus, Recombinant (Avi), Biotinylated

IGSF12,Mcipr1,NKRL,IRp60,LMIR1,Pigr4,MAIR-I,CLM-8,CD300a,CLM...

Cynomolgus HEK293 Cells
CD300a is an inhibitory receptor for mast cells and eosinophils in allergic inflammation (AI); however, the spatiotemporal expression of CD300a and its potential roles in the resolution of AI are still to be determined.CD300a expression on peritoneal cells is regulated from inflammation to resolution. CD300a activation on mouse bone marrow-derived mast cells regulated ALX/FPR2 expression levels following IgE-mediated activation. CD300A Protein, Cynomolgus, Recombinant (Avi), Biotinylated is expr...
TMPK-00186 CD300A Protein, Human, Recombinant (Avi)

Mcipr1,CLM-8,MAIR-I,IGSF12,NKRL,LMIR1,CLM8,IRC1,IRp60,CD300a...

Human HEK293 Cells
CD300a is an inhibitory receptor for mast cells and eosinophils in allergic inflammation (AI); however, the spatiotemporal expression of CD300a and its potential roles in the resolution of AI are still to be determined.CD300a expression on peritoneal cells is regulated from inflammation to resolution. CD300a activation on mouse bone marrow-derived mast cells regulated ALX/FPR2 expression levels following IgE-mediated activation. CD300A Protein, Human, Recombinant (Avi) is expressed in HEK293 mam...
TMPK-00559 CD300A Protein, Cynomolgus, Recombinant (Avi)

LMIR1,NKRL,CLM8,Mcipr1,Pigr4,IGSF12,MAIR-I,IRp60,IRC1,CLM-8,...

Cynomolgus HEK293 Cells
CD300a is an inhibitory receptor for mast cells and eosinophils in allergic inflammation (AI); however, the spatiotemporal expression of CD300a and its potential roles in the resolution of AI are still to be determined.CD300a expression on peritoneal cells is regulated from inflammation to resolution. CD300a activation on mouse bone marrow-derived mast cells regulated ALX/FPR2 expression levels following IgE-mediated activation. CD300A Protein, Cynomolgus, Recombinant (Avi) is expressed in HEK29...
TMPJ-00542 TPSB2 Protein, Human, Recombinant (His)

Tryptase-2,Tryptase Beta-2,TPS2,TPSB2,Tryptase II,Tryptase β...

Human HEK293 Cells
Tryptases are Trypsin-like Serine Proteases. β-Tryptases are the main isoenzymes in mast cells. Βtryptases form active tetramers with heparin proteoglycan. In the tetramer, the unique arrangement of the active sites facing a narrow central pore, β-Tryptases are resistant to macromolecule protease inhibitors . When mast cells are activated, β-Tryptases are released and participate in provoking inflammatory conditions . β-Tryptases have been implicated as mediators in the pathogenesis of asthma an...
TMPJ-00402 CD117 Protein, Human, Recombinant (hFc)

KIT,CD117,v-kit Hardy-Zuckerman 4 feline sarcoma viral oncog...

Human HEK293 Cells
C-Kit/SCF R is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to the protein kinase superfamily and CSF-1/PDGF receptor subfamily. SCF R expression on mast cells enables them to infiltrate SCF-secreting tumors where they promote tumor growth and induce local immune suppression. SCF R is up-regulated on dendritic cells by Th2-orTh17-biasing sti...
TMPH-02581 Chymase 1 Protein, Mouse, Recombinant (His)

Mast cell protease 5,Mast cell protease I,...

Mouse E. coli
Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion. Chymase 1 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 29.2 kDa and the accession number is P21844.
TMPY-03968 Secretogranin II Protein, Human, Recombinant (His)

EM66,SgII,SN,CHGC,secretogranin II

Human HEK293 Cells
Kit ligand, also known as Hematopoietic growth factor KL, Mast cell growth factor, Steel factor, Stem cell factor, c-Kit ligand, Kitlg and KITL, is a single-pass type I membrane protein that belongs to the SCF family. KITL / kit ligand also belongs to the family of dimeric transmembrane growth factors. The soluble form of KIT ligand is a secreted protein. Mast cells are thought to participate in a variety of immune responses, such as parasite resistance and the allergic reaction. Mast cell devel...
TMPK-00049 IL-3 Protein, Mouse, Recombinant (hFc)

IL3,MULTI-CSF,MCGF,白细胞介素,IL-3MGC79398,IL-3,白介素,interleukin-3

Mouse HEK293 Cells
Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenitors. This CSF induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes. IL-3 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 42.2 kDa and the accession num...
TMPK-00590 IL-3 Protein, Human, Recombinant (E. coli)

interleukin-3,IL-3,MULTI-CSF,MCGF,IL-3MGC79398,IL3

Human E. coli
Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenitors. This CSF induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes. IL-3 Protein, Human, Recombinant(E. coli) is expressed in E. coli expression system. The predicted molecular weight is 15.09 kDa and the accession number is A...
TMPK-00655 IL-3 Protein, Cynomolgus, Recombinant (His)

MCGF,IL3,MULTI-CSF,IL-3MGC79398,interleukin-3,IL-3

Cynomolgus E. coli
Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenitors. This CSF induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes. IL-3 Protein, Cynomolgus, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 15.13 kDa and the acce...
TMPK-00032 IL-3 Protein, Human, Recombinant (His & Avi), Biotinylated

白细胞介素,白介素,interleukin-3,MULTI-CSF,IL-3,IL3,IL-3MGC79398,MCGF

Human E. coli
Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenitors. This CSF induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes. IL-3 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in E. coli expression system with N-His-Avi tag. The predicted molecular weight is 16....
TMPH-03396 TPSAB1 Protein, Rat, Recombinant (His & Myc & SUMO)

Mast cell protease 7,Tryptase, skin,Tpsab1,Tryptase...

Rat E. coli
Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. TPSAB1 Protein, Rat, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 47.4 kDa and the accession number is P27435.
TMPK-00033 IL-3 Protein, Human, Recombinant (hFc)

IL3,interleukin-3,IL-3,MULTI-CSF,白介素,白细胞介素,IL-3MGC79398,MCGF

Human HEK293 Cells
Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenitors. This CSF induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes. IL-3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 41.6 kDa and the accession num...
TMPH-02258 TPSB2 Protein, Human, Recombinant (E. coli, His)

Tryptase II,TPSB2,Tryptase beta-2

Human E. coli
Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. TPSB2 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 31.4 kDa and the accession number is P20231.
TMPH-02957 TPSAB1 Protein, Mouse, Recombinant (His)

Tryptase,Tryptase alpha/beta-1,Mast cell protease 7...

Mouse E. coli
Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. TPSAB1 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 30.1 kDa and the accession number is Q02844.
TMPH-03267 CD300f/CD300LF Protein, Rat, Recombinant (His & Myc & SUMO)

Clm1,Cd300lf,CD300 antigen-like family member F,CLM-1,CD300f...

Rat E. coli
Acts as an inhibitory receptor for myeloid cells and mast cells. Positively regulates the phagocytosis of apoptotic cells (efferocytosis) via phosphatidylserine (PS) recognition; recognizes and binds PS as a ligand which is expressed on the surface of apoptotic cells. Plays an important role in the maintenance of immune homeostasis, by promoting macrophage-mediated efferocytosis and by inhibiting dendritic cell-mediated efferocytosis. Negatively regulates Fc epsilon receptor-dependent mast cell ...
TMPK-00031 IL-3 Protein, Human, Recombinant (His & Avi)

IL-3,IL3,IL-3MGC79398,白介素,interleukin-3,MULTI-CSF,白细胞介素,MCGF

Human E. coli
Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenitors. This CSF induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes. IL-3 Protein, Human, Recombinant (His & Avi) is expressed in E. coli expression system with N-His-Avi tag. The predicted molecular weight is 16.9 kDa and the ...
TMPH-03328 Mcpt1 Protein, Rat, Recombinant (Myc)

Mast cell protease I,Mcpt1,Chymase,Mast ce...

Rat E. coli
Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion. May participate in generating perivascular beta-protein which ultimately aggregates into amyloid-beta deposits. Mcpt1 Protein, Rat, Recombinant (Myc) is expressed in E. coli expression system with N-Myc tag. The predicted molecular weight is 28.6 kDa and the accession number is P09650.
TMPH-02257 TPSB2 Protein, Human, Recombinant (His & Myc)

Tryptase beta-2,TPSB2,Tryptase II

Human P. pastoris (Yeast)
Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. TPSB2 Protein, Human, Recombinant (His & Myc) is expressed in yeast with C-6xHis-Myc tag. The predicted molecular weight is 31.2 kDa and the accession number is P20231.
TMPK-00026 IL-9 Protein, Mouse, Recombinant (hFc)

P40,IL-9,Interleukin-9,Cytokine P40,T-cell growth factor P40...

Mouse HEK293 Cells
IL-9 is a pleiotropic cytokine that influences various distinct functions of different target cells such as T cells, B cells, mast cells and airway epithelial cells by activating STAT1, STAT3 and STAT5. Because of its pleiotropic functions, IL-9 has been demonstrated to be involved in several diseases, such as cancer, autoimmunity and other pathogen-mediated immune-regulated diseases. In this review, we focus on the role of Th9 and IL-9-producing cells in allergic asthma. IL-9 Protein, Mouse, Re...
TMPK-00039 TSLP Protein, Human, Recombinant (His & Avi), Biotinylated

TSLP,thymic stromal lymphopoietin

Human HEK293 Cells
Thymic Stromal Lymphopoietin (TSLP) was originally identified as an activity from the conditioned medium of a mouse thymic stromal cell line that promoted the development of B cells. Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c dendritic cells. Can induce allergic inflammation by directly activating mast cells. TSLP Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells ...
TMPK-00037 TSLP Protein, Human, Recombinant (His & Avi)

TSLP,thymic stromal lymphopoietin

Human HEK293 Cells
Thymic Stromal Lymphopoietin (TSLP) was originally identified as an activity from the conditioned medium of a mouse thymic stromal cell line that promoted the development of B cells. Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c dendritic cells. Can induce allergic inflammation by directly activating mast cells. TSLP Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi...
TMPY-01027 Mast Cell Protease-1/MCPT-1 Protein, Mouse, Recombinant (His)

carnitine palmitoyltransferase 1B (muscle),AV080368,Mcp-1

Mouse HEK293 Cells
Mast Cell Protease 1 (MMCP-1), also known as MCP-1, MCPT-1 and β-chymase, is a member of the Chymase family of chymotrypsin-like serine proteases. MCPT-1 is a 26 kDa β-chymase that is a component of mast cell granules. It is a 226 amino acid (aa) protein that has a conserved pattern of six cysteines and one potential glycosylation site. The granule-derived mouse mast cell proteases-1 and -2 (mMCP-1 and -2) colocalize in similar quantities in mucosal mast cells but micrograms of mMCP-1 compared w...
TMPK-01303 TPSAB1 protein, Cynomolgus, Recombinant (His)

Tryptase alpha/beta-1,TPSB1,Tryptase I,TPS2,TPS1,Tryptase al...

Cynomolgus E. coli
TPSAB1, namely tryptase alpha/beta-1, is a serine protease with trypsin­like activity. TPSAB1 is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. It may play a role in innate immunity. Diseases associated with TPSAB1 include mastocytosis and systemic mastocytosis.
TMPJ-00281 CADM1 Protein, Mouse, Recombinant (hFc)

IgSF4,NECL-2,Nectin-like protein 2,Immunoglobulin superfamil...

Mouse HEK293 Cells
Cell adhesion molecule 1(CADM1) is a single-pass type I membrane protein and belongs to the nectin family. It contains 2 Ig-like C2-type (immunoglobulin-like) domains and 1 Ig-like V-type (immunoglobulin-like) domain. CADM1 acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells. Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in...
TMPK-00025 IL-9 Protein, Human, Recombinant (hFc)

HP40,Cytokine P40,白细胞介素,Interleukin-9,白介素,P40,T-cell growth ...

Human HEK293 Cells
IL-9 is a pleiotropic cytokine that influences various distinct functions of different target cells such as T cells, B cells, mast cells and airway epithelial cells by activating STAT1, STAT3 and STAT5. Because of its pleiotropic functions, IL-9 has been demonstrated to be involved in several diseases, such as cancer, autoimmunity and other pathogen-mediated immune-regulated diseases. In this review, we focus on the role of Th9 and IL-9-producing cells in allergic asthma. IL-9 Protein, Human, Re...
TMPK-00040 TSLP Protein, Human, Recombinant (R127A & R130A, His & Avi), Biotinylated

Thymic stromal lymphopoietin,TSLP

Human HEK293 Cells
Thymic Stromal Lymphopoietin (TSLP) was originally identified as an activity from the conditioned medium of a mouse thymic stromal cell line that promoted the development of B cells. Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c dendritic cells. Can induce allergic inflammation by directly activating mast cells. TSLP Protein, Human, Recombinant (R127A & R130A, His & Avi), Biotinylated is expressed in HEK293 m...
TMPK-00617 IL-13 Protein, Human, Recombinant (His & Avi)

NC30,ALRH,IL13,MGC116786,MGC116789,P600,MGC116788,BHR1,IL-13...

Human HEK293 Cells
Interleukin-13 (IL-13) is a monomeric 17 kDa immunoregulatory cytokine that plays a key role in the pathogenesis of allergy, cancer, and tissue fibrosis. It is secreted by several helper T cell subsets, NK cells, mast cells, eosinophils, basophils, and visceral smooth muscle cells. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses. Positively regulates IL31RA expression in macro...
TMPK-00482 TSLP Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated

thymic stromal lymphopoietin,TSLP

Cynomolgus HEK293 Cells
Thymic Stromal Lymphopoietin (TSLP) was originally identified as an activity from the conditioned medium of a mouse thymic stromal cell line that promoted the development of B cells. Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c dendritic cells. Can induce allergic inflammation by directly activating mast cells. TSLP Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated is expressed in...
TMPK-00038 TSLP Protein, Human, Recombinant (R127A & R130A, His & Avi)

thymic stromal lymphopoietin,TSLP

Human HEK293 Cells
Thymic Stromal Lymphopoietin (TSLP) was originally identified as an activity from the conditioned medium of a mouse thymic stromal cell line that promoted the development of B cells. Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c dendritic cells. Can induce allergic inflammation by directly activating mast cells. TSLP Protein, Human, Recombinant (R127A & R130A, His & Avi) is expressed in HEK293 mammalian cells...
TMPK-00568 IL-9 Protein, Cynomolgus, Recombinant (His)

P40,HP40,IL-9,T-cell growth factor P40,Interleukin-9,Cytokin...

Cynomolgus HEK293 Cells
IL-9 is a pleiotropic cytokine that influences various distinct functions of different target cells such as T cells, B cells, mast cells and airway epithelial cells by activating STAT1, STAT3 and STAT5. Because of its pleiotropic functions, IL-9 has been demonstrated to be involved in several diseases, such as cancer, autoimmunity and other pathogen-mediated immune-regulated diseases. In this review, we focus on the role of Th9 and IL-9-producing cells in allergic asthma. IL-9 Protein, Cynomolgu...
TMPJ-00233 CD200R1/CRTR2 Protein, Human, Recombinant (His)

Cell Surface Glycoprotein CD200 Receptor 1,OX2R,MOX2R,CD200 ...

Human HEK293 Cells
Cell surface glycoprotein CD200 Receptor 1 (CD200R1) is the receptor for the CD200 (OX-2) membrane glycoprotein. CD200R1 contains one C2- type Ig-like domain and one V-type Ig-like domain within its extracellular domain and a PTB-signaling motif in cytoplasmic domain. CD200R1 and CD200 associate via their respective N-terminal Ig-like domains. CD200R1 is restricted primarily to mast cells, basophils, macrophages, and dendritic cells. It propagates inhibitory signals despite its lacking a cytopla...
TMPJ-01338 TSLP Protein, Mouse, Recombinant (hFc)

Thymic stromal lymphopoietin,Thymic stroma-derived lymphopoi...

Mouse HEK293 Cells
Thymic stromal lymphopoietin (TSLP) is a protein belonging to the cytokine family, contains 140 amino acids. It is known to play an important role in the maturation of T cell populations through activation of antigen presenting cells. TSLP induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c+ dendritic cells. It can induce allergic inflammation by directly activating mast cells. TSLP is produced mainly by non-hematopoietic cells ...
TMPH-03296 Galectin-3/LGALS3 Protein, Rat, Recombinant (His)

Lgals3,IgE-binding protein,Carbohydrate-binding protein 35,L...

Rat E. coli
Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. Together with TRIM16, coordinates the recognition of membrane damage with mobilization of the core autop...
TMPJ-01323 NTAL Protein, Human, Recombinant (His)

Williams-Beuren Syndrome Chromosomal Region 5 P,Membrane-Ass...

Human HEK293 Cells
Linker for Activation of T-Cells Family Member 2 (LAT2) is a single-pass type III membrane protein. LAT2 is highly expressed in the spleen, peripheral blood lymphocytes, and germinal centers of lymph nodes. LAT2 is involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. It may also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. ...
TMPH-03390 TRPV2 Protein, Rat, Recombinant (His)

Transient receptor potential cation channel subfamily V memb...

Rat E. coli
Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by growth factors, like IGF1, PDGF and morphogenetic neuropeptide/head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius; is not activated by vanilloids and acidic pH. TRPV2 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 88.2 kDa and th...
TMPJ-00898 CD72 Protein, Human, Recombinant (Trx & His)

Lyb-2,B-Cell Differentiation Antigen CD72,CD72

Human E. coli
B-Cell Differentiation Antigen CD72 (CD72) is a single-pass type II membrane protein. CD72 exists as a disulfide-linked homodimer and contains one C-type lectin domain. CD72 is expressed on B lineage cells, NK cells, monocytes, dendritic cells, and mast cells. CD72 is a ligand for CD5. CD72 associates with CD5, interacts with PTPN6/SHP-1 and plays a role in B-cell proliferation and differentiation. CD72 associates with CD79A in the B cell antigen receptor (BCR) complex following antigen stimulat...
TMPK-00149 Fc epsilon RI alpha/FCER1a Protein, Human, Recombinant (His)

Fc-ε RI-α,Fc-epsilon RI-alpha,FCER1A,Fc-epsilon RI-α,FCE1A,F...

Human HEK293 Cells
Known susceptibility genes to atopy and asthma have been identified by linkage or associations with clinical phenotypes, including total serum IgE levels. IgE-mediated sensitivity reactions require a high-affinity IgE receptor (FcepsilonRI), which immobilizes the immunoglobulin on the surface of the effector cells, mostly mast cells and basophils. Similarly to the previously investigated beta subunit of the receptor, FCER1A is a good candidate for a quantitative trait locus (QTL) in allergic dis...
TMPY-02242 Serpin B6 Protein, Human, Recombinant (His)

DKFZp686I04222,PTI,SPI3,PI-6,RP1-90J20.6,serpin peptidase in...

Human Baculovirus Insect Cells
SerpinB6, also known as Cytoplasmic antiproteinase, Peptidase inhibitor 6, Placental thrombin inhibitor, SERPINB6 and PI-6, is a cytoplasm protein that belongs to the serpin family and Ov-serpin subfamily. SerpinB6 / PI-6 is an inhibitor of cathepsin G, kallikrein-8 and thrombin. It may play an important role in the inner ear in the protection against leakage of lysosomal content during stress and loss of this protection results in cell death and sensorineural hearing loss. SerpinB6 / PI-6 is ex...
TMPK-01165 MCEMP1 Protein, Mouse, Recombinant (hFc)

MGC132456,C19orf59,MCEMP1

Mouse HEK293 Cells
A cecal ligation and puncture-induced sepsis mouse model was established to determine the expression of mast cell expression membrane protein 1 (MCEMP1). MCEMP1 in T lymphocytes isolated from sepsis mice were up- or downregulated by exogenous transfection in an attempt to investigate their effects on the release of inflammatory factors, the expression of immunoglobulins, the activity of T cell subsets and natural killer (NK) cells, as well as T lymphocyte apoptosis.
TMPH-03107 Complement C5a Protein, Pig, Recombinant (His)

Complement C5a anaphylatoxin,C5

Sus scrofa (Pig) P. pastoris (Yeast)
Derived from proteolytic degradation of complement C5, C5a anaphylatoxin is a mediator of local inflammatory process. Binding to the receptor C5AR1 induces a variety of responses including intracellular calcium release, contraction of smooth muscle, increased vascular permeability, and histamine release from mast cells and basophilic leukocytes. C5a is also a potent chemokine which stimulates the locomotion of polymorphonuclear leukocytes and directs their migration toward sites of inflammation....
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重组蛋白

IL-3 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00051
Species: Mouse
Expression System: HEK293 Cells
TPSAB1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01204
Species: Human
Expression System: HEK293 Cells
GM-CSF/CSF2 Protein, Human, Recombinant (E. coli)
Cat.No: TMPJ-01465
Species: Human
Expression System: E. coli
TSLP Protein, Human, Recombinant
Cat.No: TMPJ-00042
Species: Human
Expression System: E. coli
CD300A Protein, Human, Recombinant (hFc & His)
Cat.No: TMPJ-00187
Species: Human
Expression System: HEK293 Cells
CD300A Protein, Mouse, Recombinant (His)
Cat.No: TMPK-00212
Species: Mouse
Expression System: HEK293 Cells
CD300A Protein, Human, Recombinant (Avi), Biotinylated
Cat.No: TMPK-00187
Species: Human
Expression System: HEK293 Cells
Allergin-1 Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02499
Species: Mouse
Expression System: E. coli
CD300A Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00561
Species: Cynomolgus
Expression System: HEK293 Cells
CD300A Protein, Cynomolgus, Recombinant (Avi), Biotinylated
Cat.No: TMPK-00560
Species: Cynomolgus
Expression System: HEK293 Cells
CD300A Protein, Human, Recombinant (Avi)
Cat.No: TMPK-00186
Species: Human
Expression System: HEK293 Cells
CD300A Protein, Cynomolgus, Recombinant (Avi)
Cat.No: TMPK-00559
Species: Cynomolgus
Expression System: HEK293 Cells
TPSB2 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00542
Species: Human
Expression System: HEK293 Cells
CD117 Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00402
Species: Human
Expression System: HEK293 Cells
Chymase 1 Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02581
Species: Mouse
Expression System: E. coli
Secretogranin II Protein, Human, Recombinant (His)
Cat.No: TMPY-03968
Species: Human
Expression System: HEK293 Cells
IL-3 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPK-00049
Species: Mouse
Expression System: HEK293 Cells
IL-3 Protein, Human, Recombinant (E. coli)
Cat.No: TMPK-00590
Species: Human
Expression System: E. coli
IL-3 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00655
Species: Cynomolgus
Expression System: E. coli
IL-3 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00032
Species: Human
Expression System: E. coli
TPSAB1 Protein, Rat, Recombinant (His & Myc & SUMO)
Cat.No: TMPH-03396
Species: Rat
Expression System: E. coli
IL-3 Protein, Human, Recombinant (hFc)
Cat.No: TMPK-00033
Species: Human
Expression System: HEK293 Cells
TPSB2 Protein, Human, Recombinant (E. coli, His)
Cat.No: TMPH-02258
Species: Human
Expression System: E. coli
TPSAB1 Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02957
Species: Mouse
Expression System: E. coli
CD300f/CD300LF Protein, Rat, Recombinant (His & Myc & SUMO)
Cat.No: TMPH-03267
Species: Rat
Expression System: E. coli
IL-3 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00031
Species: Human
Expression System: E. coli
Mcpt1 Protein, Rat, Recombinant (Myc)
Cat.No: TMPH-03328
Species: Rat
Expression System: E. coli
TPSB2 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-02257
Species: Human
Expression System: P. pastoris (Yeast)
IL-9 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPK-00026
Species: Mouse
Expression System: HEK293 Cells
TSLP Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00039
Species: Human
Expression System: HEK293 Cells
TSLP Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00037
Species: Human
Expression System: HEK293 Cells
Mast Cell Protease-1/MCPT-1 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01027
Species: Mouse
Expression System: HEK293 Cells
TPSAB1 protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-01303
Species: Cynomolgus
Expression System: E. coli
CADM1 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPJ-00281
Species: Mouse
Expression System: HEK293 Cells
IL-9 Protein, Human, Recombinant (hFc)
Cat.No: TMPK-00025
Species: Human
Expression System: HEK293 Cells
TSLP Protein, Human, Recombinant (R127A & R130A, His & Avi), Biotinylated
Cat.No: TMPK-00040
Species: Human
Expression System: HEK293 Cells
IL-13 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00617
Species: Human
Expression System: HEK293 Cells
TSLP Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated
Cat.No: TMPK-00482
Species: Cynomolgus
Expression System: HEK293 Cells
TSLP Protein, Human, Recombinant (R127A & R130A, His & Avi)
Cat.No: TMPK-00038
Species: Human
Expression System: HEK293 Cells
IL-9 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00568
Species: Cynomolgus
Expression System: HEK293 Cells
CD200R1/CRTR2 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00233
Species: Human
Expression System: HEK293 Cells
TSLP Protein, Mouse, Recombinant (hFc)
Cat.No: TMPJ-01338
Species: Mouse
Expression System: HEK293 Cells
Galectin-3/LGALS3 Protein, Rat, Recombinant (His)
Cat.No: TMPH-03296
Species: Rat
Expression System: E. coli
NTAL Protein, Human, Recombinant (His)
Cat.No: TMPJ-01323
Species: Human
Expression System: HEK293 Cells
TRPV2 Protein, Rat, Recombinant (His)
Cat.No: TMPH-03390
Species: Rat
Expression System: E. coli
CD72 Protein, Human, Recombinant (Trx & His)
Cat.No: TMPJ-00898
Species: Human
Expression System: E. coli
Fc epsilon RI alpha/FCER1a Protein, Human, Recombinant (His)
Cat.No: TMPK-00149
Species: Human
Expression System: HEK293 Cells
Serpin B6 Protein, Human, Recombinant (His)
Cat.No: TMPY-02242
Species: Human
Expression System: Baculovirus Insect Cells
MCEMP1 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPK-01165
Species: Mouse
Expression System: HEK293 Cells
Complement C5a Protein, Pig, Recombinant (His)
Cat.No: TMPH-03107
Species: Sus scrofa (Pig)
Expression System: P. pastoris (Yeast)
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Cat. No. Product Name Target Signaling Pathways
TMIH-0512 Salbutamol-d3

Salbutamol-d3 是 Salbutamol 的氘代化合物。Salbutamol 的 CAS 号为 18559-94-9。Salbutamol 是短效的 β2 肾上腺素受体激动剂,用于哮喘和慢性阻塞性肺疾病 (COPD) 引发的支气管痉挛的研究。
TMID-0233 Salbutamol-d9

Salbutamol-d9 是 Salbutamol 的氘代化合物。Salbutamol 的 CAS 号为 18559-94-9。Salbutamol 是短效的 β2 肾上腺素受体激动剂,用于哮喘和慢性阻塞性肺疾病 (COPD) 引发的支气管痉挛的研究。

同位素标记化合物

Salbutamol-d3
Cat.No: TMIH-0512
Synonym:
Target:
Salbutamol-d9
Cat.No: TMID-0233
Synonym:
Target:
TargetMol Loading
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