6
9
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T73610 |
Lipoprotein lipase
|
Others | Others |
Lipoprotein lipase 是来自于脂肪组织、心肌和骨骼肌、胰岛和巨噬细胞的多功能酶。Lipoprotein lipase 促进正常脂蛋白代谢、组织特异性底物的输送和利用。Lipoprotein lipase 催化脂质在血液循环的限速步骤。 | |||
T7832 |
Ibrolipim
NO-1886 |
LPL Receptor | GPCR/G Protein |
Ibrolipim (NO-1886) 是口服具有活力的脂蛋白脂肪酶 (LPL) 激活剂。它能够降低血浆甘油三酸酯,增加高密度脂蛋白胆固醇水平,具有肾保护和降血脂的作用。 | |||
T41160 |
Lalistat 2
|
Lipase | Metabolism |
Lalistat 2 是一种溶酶体酸性脂肪酶的特异性抑制剂,IC50 为 152 nM,对人胰脂肪酶或牛乳脂蛋白脂肪酶没有抑制作用(高达 10 μM)。 | |||
T1415 |
Gemfibrozil
吉非罗齐,CI-719,Jezil,Decrelip,Lopid |
P450; Adrenergic Receptor; PPAR | DNA Damage/DNA Repair; GPCR/G Protein; Metabolism; Neuroscience |
Gemfibrozil (CI-719) 是一种PPAR-α激活剂,可作为降脂药。它也是P450非选择性抑制剂,对 CYP2C9、2C19、2C8 和 1A2 的Ki 值分别为 5.8、24、69 和 82 μM。 | |||
T22816 |
GSK 264220A
|
Others | Others |
endothelial lipase and lipoprotein lipase inhibitor | |||
T27228 |
E-3030 free acid
E-3030,E3030,E 3030 |
Others | Others |
E-3030 free acid is a peroxisome proliferator-activated receptor (PPAR) agonist. E-3030 decreased blood glucose, triglyceride, non-esterified fatty acids, and insulin levels and increased blood adiponectin levels. Triglyceride- and non-high-density lipopr |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-06409 |
LPL Protein, Chinese hamster, Recombinant (His)
lipoprotein lipase |
Chinese hamster | E. coli |
LPL Protein, Chinese hamster, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 51.35 kDa and the accession number is G3H6V7-1. | |||
TMPH-02760 |
LPL Protein, Mouse, Recombinant (His & Myc)
Phospholipase A1,Lpl,Lipoprotein lipas... |
Mouse | E. coli |
LPL Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 57.3 kDa and the accession number is P11152. | |||
TMPH-02761 |
LPL Protein, Mouse, Recombinant (His)
Phospholipase A1,Lipoprotein lipase |
Mouse | Baculovirus Insect Cells |
LPL Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with N-10xHis tag. The predicted molecular weight is 52.8 kDa and the accession number is P11152. | |||
TMPH-02762 |
LPL Protein, Mouse, Recombinant
Phospholipase A1,Lipoprotein lipase |
Mouse | E. coli |
LPL Protein, Mouse, Recombinant is expressed in E. coli. | |||
TMPH-00947 |
APOC2 Protein, Human, Recombinant (His & SUMO)
ApoC-II,APC2,Apolipoprotein C-II,Apolipoprotein... |
Human | E. coli |
Component of chylomicrons, very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL) in plasma. Plays an important role in lipoprotein metabolism as an activator of lipoprotein lipase. Both proapolipoprotein C-II and apolipoprotein C-II can activate lipoprotein lipase. In normolipidemic individuals, it is mainly distributed in the HDL, whereas in hypertriglyceridemic individuals, predominantly found in the VLDL and LDL. APOC2 Protein, Human, Recomb... | |||
TMPH-02514 |
APOA4 Protein, Mouse, Recombinant (His)
Apolipoprotein A4,Apolipoprotein A-IV,ApoA... |
Mouse | P. pastoris (Yeast) |
May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons. | |||
TMPJ-00601 |
Apolipoprotein C-II/APOC2 Protein, Human, Recombinant (His)
Apolipoprotein C2,Apolipoprotein C-II,APC2... |
Human | E. coli |
APOC2 activates the lipoprotein lipase in capillaries, which hydrolyzes triglycerides and thus provides free fatty acids for cells. APOC2 is component of the very low density lipoprotein (VLDL) fraction in plasma. It is also an activator of several triacylglycerol lipases. The association of APOC2 with plasma chylomicrons, VLDL, and HDL is reversible, a function of the secretion and catabolism of triglyceride-rich lipoproteins, and changes rapidly. Defects in APOC2 are the cause of hyperlipoprot... | |||
TMPJ-00286 |
ANGPTL3 Protein, Human, Recombinant (hFc)
ANGPTL3,ANGPT5,Angiopoietin-related protein 3,ANG-5,Angiopoi... |
Human | HEK293 Cells |
Angiopoietin-like 3 (ANGPTL3) is a secreted glycoprotein that is structurally related to the angiopoietins. Mature human ANGPTL3 contains an N-terminal coiled coil domain and a C-terminal fibrinogen-like domain. ANGPTL3 is expressed in the liver from early in development through adulthood. Full length ANGPTL3 circulates in the plasma as do the proteolytically separated N-and C-terminal segments containing the coiled coil domain and fibrinogen-like domains,respectively. ANGPTL3 directly inhibits ... | |||
TMPJ-01071 |
Apolipoprotein H/APOH Protein, Mouse, Recombinant (His)
Beta-2-glycoprotein 1,Apoh,β-2-glycoprotein 1 |
Mouse | HEK293 Cells |
Apolipoprotein H (APOH), also known as Beta-2-glycoprotein 1, is a glycoprotein synthesized by liver cells and it is present in the blood associated with plasma lipoproteins. Its carbohydrate content is approximately 19% of the molecular weight and it is present in the blood associated with plasma lipoproteins. Mature mouse ApoH shares 76% and 42% aa sequence identity with human and rat ApoH, respectively. The activity of APOH appears to involve the binding of agglutenating, inhibits agglutinati... |