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Targets Recommended: COX

23

抑制剂 & 化合物

2

天然产物

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Cat. No. Product Name Target Signaling Pathways
T0961 Trometamol

三(羟甲基)氨基甲烷,Tromethamine,缓血酸铵

COX Immunology/Inflammation; Neuroscience
Trometamol (Tromethamine) 是一种在生理范围内控制 pH 值的有效胺类化合物,也是一种低毒性的生物惰性氨基醇,可以在体内和体外缓冲二氧化碳和酸。
T23478 Trometamol hydrochloride

TRIS hydrochloride,三(羟甲基)氨基甲烷盐酸盐

Others Others
Trometamol hydrochloride (TRIS hydrochloride) 是低毒性的生物惰性氨基醇,可以在体内、外缓冲二氧化碳和酸,能用于生理范围内控制 pH 值。
T16034 Meclinertant

SR 48692

Neurotensin Receptor GPCR/G Protein
Meclinertant (SR 48692) 是神经降压素受体-1(NT1)拮抗剂,可阻断神经降压素诱导的兴奋,可用于研究神经系统疾病。
T19805 Benoxacor

BRN-4190275,解草酮,BRN 4190275,BRN4190275

Others Others
Benoxacor (BRN-4190275) 是一种惰性农业化学品。它作为一种除草剂安全剂,可保护作物免受除草剂毒性。
TNU0123 5-Methoxyuridine

Mo5U

Apoptosis Apoptosis
5-Methoxyuridine (Mo5U) is a purine nucleoside analog with a broad spectrum of antitumor activity, targeting malignant tumors of the inert lymphatic system and inducing apoptosis.5-Methoxyuridine's anticancer mechanism is dependent on the inhibition of DNA synthesis.5-Methoxyuridine is a purine nucleoside analog with a broad spectrum of antitumor activity, targeting malignant tumors of the inert lymphatic system and inducing apoptosis.
TNU0436 2-Thiocytidine

Apoptosis; Nucleoside Antimetabolite/Analog; DNA/RNA Synthesis Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair
2-Thiocytidine 是一种靶向惰性淋巴系统恶性肿瘤的嘌呤核苷类似物,具有广泛的抗肿瘤活性。2-Thiocytidine 通过抑制 DNA 合成诱导细胞凋亡 (apoptosis) 。
TNU0022 6-Azauridine

6-Azuridine

Apoptosis Apoptosis
6-Azauridine (6-Azuridine) is a purine nucleoside analog with a broad spectrum of antitumor activity, targeting malignant tumors of the inert lymphatic system and inducing apoptosis.6-Azuridine's anticancer mechanism is dependent on the inhibition of DNA synthesis.
TNU0352 1-beta-D-Arabinofuranosylthymine

Thymine 1-β-D-arabinofuranoside,Spongothymidine

Apoptosis Apoptosis
1-beta-D-Arabinofuranosylthymine (Thymine 1-β-D-arabinofuranoside) is a purine nucleoside analog. Purine nucleoside analogs have a broad spectrum of antitumor activity, targeting inert lymphoid malignancies and inducing apoptosis.1-beta-D-Arabinofuranosylthymine's anticancer mechanism is dependent on the inhibition of DNA synthesis.1-beta-D-Arabinofuranosylthymine is a purine nucleoside analog.
T31786 Magnetite

Magnetic Black,Black Iron BM,Magnetic oxide,Black Gold F 89,11557 Black

Others Others
Magnetite 也称为氧化亚铁, 是一种稳定、化学惰性、红棕色的磁性材料。
T21017 5'-Amino-5'-deoxyadenosine

5' Amino 5' deoxyadenosine,5'Amino5'deoxyadenosine,Nsc 238990,NH2dAdo

Apoptosis; Adenosine Receptor Apoptosis; GPCR/G Protein; Neuroscience
5'-Amino-5'-deoxyadenosine (NH2dAdo) 是一种针对惰性淋巴系统恶性肿瘤的腺苷激酶抑制剂,具有抗肿瘤和抗癌作用。5'-Amino-5'-deoxyadenosine 的抗癌机制通过抑制 DNA 合成,诱导细胞凋亡 (apoptosis) 等来实现。
TNU0839 1,4-Dideoxy-1,4-epithio-D-ribitol

Apoptosis; Nucleoside Antimetabolite/Analog; DNA/RNA Synthesis Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair
1,4-Dideoxy-1,4-epithio-D-ribitol 是一种靶向惰性淋巴系统恶性肿瘤的嘌呤核苷类似物,具有广泛的抗肿瘤活性。1,4-Dideoxy-1,4-epithio-D-ribitol 通过抑制 DNA 合成诱导细胞凋亡 (apoptosis) 。
TNU0168 2'-Deoxy-2'-fluoro-beta-D-arabinoguanosine

Apoptosis Apoptosis
Nucleoside Derivatives - Fluoro-modified nucleosides, Arabino-nucleosides, 2’-Modified nucleosides; Drugs and Inhibitors; Anticancer agent; Impurity C of Clofarabine
T1098 Denatonium benzoate

苯甲地那铵,THS-839

Others Others
Denatonium benzoate (THS-839) 是一种已知的最苦的化合物,可作为厌恶剂(苦味剂),加入到工业酒精、防冻液、咬指甲癖预防、呼吸器面罩配合测试、动物驱虫剂、液体皂和洗发水中,防止不适当的摄取。
TNU0630 2'-O-Methyl-5-iodouridine

5-Iodo-2'-O-methyluridine

Others Others
2'-O-Methyl-5-iodouridine (5-Iodo-2'-O-methyluridine) 是一种靶向惰性淋巴系统恶性肿瘤的嘌呤核苷类似物,具有广泛的抗肿瘤活性。2'-O-Methyl-5-iodouridine 的抗癌机制依赖于抑制 DNA 合成,诱导细胞凋亡 (apoptosis) 。
T40973 MDNI-caged-L-glutamate

MDNI-caged-L-glutamate,MDNI-glu

Others Others
MDNI-glu is a photosensitive derivative of L-glutamate, a major excitatory amino acid, that is biologically inert. It demonstrates improved utilization of incident light.
T84975 4-CF3-TPP-DC

4-CF3-Triphenylphosphonium-DC

Others Others
4-CF3-TPP-DC is an inert mitochondriotropic carrier that does not induce mitochondrial depolarization or cell death in C2C12 cells.
T39050 Pitnot-2

Others Others
Pitnot-2 is an inert analogue of the clathrin inhibitor Pitstop 2, commonly employed as a negative control in experimental studies.
T21075 Perfluoro(1,3-dimethylcyclohexane)

Cyclohexane, perfluoro-1,3-dimethyl-,Hexadecafluoro-1,3-dimethylcyclohexane,Cyclohexane, decafluoro-1,3-bis(trifluoromethyl)-

Others Others
Perfluoro-1,3-dimethylcyclohexane is used as a synthesis reagent for amorphous fluorocarbon film preparation by plasma polymerization, and for the hydroformylation of linear terminal alkenes. As a chemically inert compound, it is similar in properties to
T76984 Tecaginlimab

Tecaginlimab (BNT-312) 是一种 Fc 惰性双特异性抗体,用于CD40和4-1BB 的双重靶向和条件刺激。Tecaginlimab 可以增强肿瘤特异性免疫的启动和再激活。
TP1189 C-Peptide, dog

C-Peptide (dog)

C-Peptide, dog is a component of proinsulin, released from pancreatic beta cells into blood together with insulin. The C-peptide of proinsulin is important for the biosynthesis of insulin but has for a long time been considered to be biologically inert.
TNU1041 3’-Deoxy-1,2-O-isopropylidene-5-O-(p-toluoyl)-L-arabinofuranose

Others Others
3’-Deoxy-1,2-O-isopropylidene-5-O-(p-toluoyl)-L-arabinofuranose 是一种嘌呤核苷类似物,通过抑制DNA 合成、诱导细胞凋亡发挥抗肿瘤活性,它可以靶向惰性淋巴系统恶性肿瘤。
T77228 Polyoxyethylene Sorbitan Monostearate

Others Others
Polyoxyethylene Sorbitan Monostearate 是一种由饱和脂肪酸硬脂酸 (C18:0) 构成的酯,广泛应用作药用辅料,包括表面活性剂、乳化剂、增溶剂和润湿剂。作为药用助剂,其主要作用是改善药物制剂的稳定性、溶解性和加工性,同时对药物的吸收、分布、代谢和消除 (ADME) 过程具有影响。
T38071 HPF

The biology of highly reactive oxygen radical species is of great interest in many biomedical research disciplines, including neurodegeneration, aging, cancer, and infectious diseases.[1] There are a number of fluorescent reagents, such as 2,7-dichlorodihydrofluorescein (DCDHF), that can be used to detect free radicals, but they have significant limitations due to their facile oxidation by light and numerous non-radical oxidants such as hydrogen peroxide (H2O2). [2] HPF is a cell-permeable aroma...

化合物

Trometamol
Cat.No: T0961
Synonym: 三(羟甲基)氨基甲烷,Tromethamine,缓血酸铵
Target: COX
Trometamol hydrochloride
Cat.No: T23478
Synonym: TRIS hydrochloride,三(羟甲基)氨基甲烷盐酸盐
Target: Others
Meclinertant
Cat.No: T16034
Synonym: SR 48692
Target: Neurotensin Receptor
Benoxacor
Cat.No: T19805
Synonym: BRN-4190275,解草酮,BRN 4190275,BRN4190275
Target: Others
5-Methoxyuridine
Cat.No: TNU0123
Synonym: Mo5U
Target: Apoptosis
2-Thiocytidine
Cat.No: TNU0436
Synonym:
Target: Apoptosis, Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis
6-Azauridine
Cat.No: TNU0022
Synonym: 6-Azuridine
Target: Apoptosis
1-beta-D-Arabinofuranosylthymine
Cat.No: TNU0352
Synonym: Thymine 1-β-D-arabinofuranoside,Spongothymidine
Target: Apoptosis
Magnetite
Cat.No: T31786
Synonym: Magnetic Black,Black Iron BM,Magnetic oxide,Black Gold F 89,11557 Black
Target: Others
5'-Amino-5'-deoxyadenosine
Cat.No: T21017
Synonym: 5' Amino 5' deoxyadenosine,5'Amino5'deoxyadenosine,Nsc 238990,NH2dAdo
Target: Apoptosis, Adenosine Receptor
1,4-Dideoxy-1,4-epithio-D-ribitol
Cat.No: TNU0839
Synonym:
Target: Apoptosis, Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis
2'-Deoxy-2'-fluoro-beta-D-arabinoguanosine
Cat.No: TNU0168
Synonym:
Target: Apoptosis
Denatonium benzoate
Cat.No: T1098
Synonym: 苯甲地那铵,THS-839
Target: Others
2'-O-Methyl-5-iodouridine
Cat.No: TNU0630
Synonym: 5-Iodo-2'-O-methyluridine
Target: Others
MDNI-caged-L-glutamate
Cat.No: T40973
Synonym: MDNI-caged-L-glutamate,MDNI-glu
Target: Others
4-CF3-TPP-DC
Cat.No: T84975
Synonym: 4-CF3-Triphenylphosphonium-DC
Target: Others
Pitnot-2
Cat.No: T39050
Synonym:
Target: Others
Perfluoro(1,3-dimethylcyclohexane)
Cat.No: T21075
Synonym: Cyclohexane, perfluoro-1,3-dimethyl-,Hexadecafluoro-1,3-dimethylcyclohexane,Cyclohexane, decafluoro-1,3-bis(trifluoromethyl)-
Target: Others
Tecaginlimab
Cat.No: T76984
Synonym:
Target:
C-Peptide, dog
Cat.No: TP1189
Synonym: C-Peptide (dog)
Target:
3’-Deoxy-1,2-O-isopropylidene-5-O-(p-toluoyl)-L-arabinofuranose
Cat.No: TNU1041
Synonym:
Target: Others
Polyoxyethylene Sorbitan Monostearate
Cat.No: T77228
Synonym:
Target: Others
HPF
Cat.No: T38071
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T41358 2-Hydroxybenzylamine

Others Others
2-Hydroxybenzylamine 是一种有效的 IsoLG 小分子清除剂,可将活性物质作为惰性加合物螯合。 2-Hydroxybenzylamine 可用于通过减少具有天然生物分子的 IsoLG 加合物来减少心房颤动消融后心房颤动和其他心房心律失常的早期复发。
TNU0052 Nebularine

9-(beta-D-Ribofuranosyl)-9H-purine

Apoptosis Apoptosis
Nebularine (9-(beta-D-Ribofuranosyl)-9H-purine),是一种嘌呤核苷类似物,具有广谱的抗肿瘤活性,针对惰性淋巴恶性肿瘤并诱导凋亡。Nebularine的抗癌机制依赖于抑制DNA合成。

天然产物

2-Hydroxybenzylamine
Cat.No: T41358
Synonym:
Target: Others
Nebularine
Cat.No: TNU0052
Synonym: 9-(beta-D-Ribofuranosyl)-9H-purine
Target: Apoptosis
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