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Search Results for " immunotherapy "

Targets Recommended: Prostaglandin Receptor

38

抑制剂 & 化合物

3

化合物库

41

重组蛋白

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Cat. No.	Product Name
L2170	肿瘤免疫治疗小分子化合物库		449 compounds
	449 种靶向肿瘤免疫治疗靶点的小分子，可用于高通量和高内涵筛选，是研究肿瘤免疫治疗的有力工具；
L2190	抗肺癌化合物库		1702 compounds
	1702 种与肺癌相关的化合物，可以用于抗肺癌药物研发和药理研究；
L2192	抗胰腺癌化合物库		2238 compounds
	2238 种与胰腺癌相关的化合物，可以用于高通量和高内涵筛选；

化合物库

肿瘤免疫治疗小分子化合物库

Cat.No: L2170

Compounds: 449

抗肺癌化合物库

Cat.No: L2190

Compounds: 1702

抗胰腺癌化合物库

Cat.No: L2192

Compounds: 2238

Cat. No.	Product Name	Target	Signaling Pathways
T11211	EP4 receptor antagonist 1	Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation
	EP4 receptor antagonist 1 是一种有效的特异性前列腺素 EP4受体拮抗剂，对人和小鼠 EP4受体的 IC50分别为6.1 nM 和16.2 nM。 EP4 receptor antagonist 1 可用于癌症免疫治疗的研究。
T7860	SM-324405 SM 324405	TLR	Immunology/Inflammation
	SM-324405 是TLR7的激动剂，EC50 为 50 nM，对人和大鼠 TLR7 的 pEC50值分别为 7.3 和 6.6，可用于过敏性疾病的免疫治疗研究。
T8961	GW280264X Carbamic acid	MMP	Proteases/Proteasome
	GW280264X (Carbamic acid) 是一种 ADAM10/TACE (ADAM17)金属蛋白酶抑制剂。它有效阻断 TACE (ADAM17)和 ADAM10的 IC50分别为 8.0 nM 和 11.5 nM。其中ADAM10/17 能够调节胶质母细胞瘤起始细胞的免疫原性。
T12516	Polyinosinic-polycytidylic acid sodium 双链聚肌胞,Poly(I:C) sodium	Apoptosis; Others; TLR	Apoptosis; Immunology/Inflammation; Others
	Polyinosinic-polycytidylic acid sodium (Poly(I:C) sodium) 是双链 RNA 的合成类似物，是TLR3和视黄酸诱导型基因 I 受体激动剂。它可以用作疫苗佐剂，直接触发癌细胞发生凋亡，还增强先天性和适应性免疫反应，并改变肿瘤的微环境。
T4349	Sitravatinib MG516,MGCD516	Discoidin Domain Receptor (DDR); VEGFR; FLT; Trk receptor; TAM Receptor; c-Kit; Ephrin Receptor	Angiogenesis; Tyrosine Kinase/Adaptors
	Sitravatinib (MGCD516) 是一种有口服活性的受体酪氨酸激酶抑制剂。它单独使用即具有有效的抗肿瘤功效，且通过促进抗肿瘤免疫微环境增强了 PD-1 阻断的活性。
T40350	HPK1-IN-4 HPK1-IN-4	MAPK	MAPK
	HPK1-IN-4是一种HPK1（MAPK41）抑制剂，IC 50为0.061 nM。HPK1-IN-4常被作为临床前免疫治疗工具化合物。
TP1493L1	PSA1 141-150 acetate PSA1 141-150 acetate(160215-60-1 free base)	Others	Others
	PSA1 141-150 acetate 用于癌症实验的免疫治疗，它是一种前列腺特异性抗原 1 肽。
T77764	DC-Y13-27	Others	Others
	DC-Y13-27 是一种 DC-Y13 的衍生物，是一种有效的 YTHDF2 抑制剂 (KD: 37.9 μM)。DC-Y13-27 具有抗肿瘤活性，可增强放疗和免疫疗法对肿瘤的响应。
T63948	PD-1/PD-L1-IN-16	Others	Others
	PD-1/PD-L1-IN-16 是 PD-1/PD-L1 的有效抑制剂 (IC50: 53.2 nM)，对肿瘤免疫治疗表现出研究潜力。
T69560	ENPP1 inhibitor 43	Others	Others
	ENPP1 inhibitor 43 is a novel small molecule for cancer immunotherapy.
TP2478	WT-1 A1 Tyr-Met-Phe-Pro-agn-Ala-Pro-Tyr-Leu
	WT-1 A1 is an attractive target for immunotherapy in patients with pancreatic adenocarcinoma.
TP1493	PSA1 (141-150) PSA1 141-150
	This Prostate Specific Antigen 1 peptide was used in the immunotherapy of cancer experiments.
T82349	GAGGVGKSA
	GAGGVGKSA，作为wild-type KRAS G12D 9mer肽，具有免疫原性，可用于研究癌症免疫疗法中新抗原的应用。
T80961	TPPC
	TPPC为卟啉胆固醇缀合物，能够提高癌细胞对ICI的敏感性，并增强肺癌光动力免疫治疗效果。
T82348	GAGGVGKSAL
	GAGGVGKSAL 是免疫原性的野生型KRAS G12D 10mer肽，用于癌症免疫疗法研究的新抗原。
T82353	GADGVGKSA
	GADGVGKSA, 作为KRAS G12D 9mer肽的变体，充当免疫原性新抗原，在癌症免疫疗法研究中具有潜在应用价值。
T83135	Alrefimotide hTERT (660–689)
	Alrefimotide为一种衍生自hTERT的免疫肽，其序列为ALFSVLNYERARRPGLLGASVLGLDDIHRA，主要应用于癌症免疫治痗研究。
T61386	CXCR2 antagonist 2	Others	Others
	CXCR2 antagonist 2 是一种有效的癌症免疫治疗的 CXCR2拮抗剂，IC50值为 95 nM。
T82352	GADGVGKSAL
	GADGVGKSAL为KRAS G12D突变型10mer肽，具有免疫原性，常用作癌症免疫疗法研究中的新型抗原。
T63457	STING agonist-10	Others	Others
	STING agonist-10 是一种 STING 小分子环脲类的有效激活剂 (EC50: 2600 nM)。STING 激活是一种具有高度潜力的免疫疗法。
T63458	STING agonist-11	Others	Others
	STING agonist-11 是一种 STING 小分子环脲类的有效激活剂 (EC50: 18 nM)。STING 激活是一种具有高度潜力的免疫疗法。
T63614	PD-1/PD-L1-IN-15	Others	Others
	PD-1/PD-L1-IN-15 是 PD-1/PD-L1 的有效抑制剂 (IC50: 60.1 nM)，对肿瘤免疫治疗表现出研究潜力。
T82268	Gotistobart BNT 316,ONC-392
	Gotistobart (ONC-392)为一种人源化抗CTLA-4抗体，旨在通过选择性消耗肿瘤微环境中的调节性T细胞(Treg)，以增强免疫疗效。
T78852	HPK1-IN-39	Others	Others
	HPK1-IN-39（Compound 10n）为一选择性HPK1抑制剂，IC50值为29 nM。该化合物能抑制SLP76磷酸化，可用于癌症免疫治疗研究。
T73186	HPK1-IN-31	Others	Others
	HPK1-IN-31 是一种具有口服活性的造血祖细胞激酶 1 (HPK1) 抑制剂，IC50值为 0.8 nM。HPK1-IN-31 具有抗肿瘤活性，在免疫治疗方面具有巨大的潜力。
T29413	3M-003 3M003,3M 003	Others	Others
	3M-003 与 Toll 样受体 7 (TLR-7) 和 TLR-8 相互作用。 3M-003 直接作用于巨噬细胞，增强真菌杀伤力，并刺激 PBMC 产生可溶性因子，增强中性粒细胞、巨噬细胞和单核细胞的杀伤力。 3M-003 可能是抗真菌免疫疗法的候选药物。
T78276	KWAR 23
	KWAR23为一种anti-human SIRPα抗体，能高亲和力结合human SIRPα并阻断其与CD47的相互作用。当与tumor-opsonizing抗体协同应用时，KWAR23展现出抗肿瘤活性，适用于癌症免疫治疗的研究。
T75103	CD19 CAR mRNA	Others	Others
	CD19CAR mRNA 能够编码CD19car蛋白，适用于CAR-T细胞免疫治疗（CAR-CD19）。CD19car作为嵌合抗原受体，针对B细胞表面的CD19，一种关键参与B细胞增殖、分化、活化及产生抗体的CD分子（即白细胞分化抗原），进而增强BCR信号传递。
T79069	TLR7/8 agonist 9	Others	Others
	TLR7/8 agonist 9 (Compound 25a) 是一种能够增强PD-1/PD-L1阻断疗法抗肿瘤效果的化合物，主要用于癌症免疫疗法研究。它对hTLR7和hTLR8的EC50分别为40 nM和23 nM，显示出其对这两种受体的高亲和力以及潜在的抗肿瘤活性。
T72839	SHP2/HDAC-IN-1	Others	Others
	SHP2/HDAC-IN-1 是一种变构的 SHP2/HDAC 双重抑制剂，IC50值分别为 20.4 nM (SHP2) 和 25.3 nM ( HDAC1)。SHP2/HDAC-IN-1 通过激活 T 细胞、增强抗原呈递功能和促进细胞因子分泌来触发抗肿瘤免疫反应。SHP2/HDAC-IN-1 可用于癌症的免疫治疗研究。
T84604	11(S)-HETE 11(S)-Hydroxyeicosatetraenoic Acid	Others	Others
	11(S)-HETE, an (S) enantiomer of 11(R)-HETE and a type of oxylipin, is non-enzymatically synthesized from arachidonic acid. Compared to its counterpart, 11(S)-HETE levels are found to be elevated in both isolated human plasma and serum, as well as in LPS-stimulated isolated human plasma. Notably, patients with allergic rhinitis exhibit a decrease in 11(S)-HETE levels in their serum following one year of double-mite subcutaneous immunotherapy (DM-SCIT), correlating with an enhanced quality of lif...
T75104	CD19 CAR circRNA	Others	Others
	CD19CAR circRNA 可以表达 CD19car 蛋白，并且可用于嵌合抗原受体 T 细胞免疫疗法 (CAR-CD19)。CD19car 是一种嵌合抗原受体。其中 CD19是 B 细胞表达的一种 CD 分子 (即白细胞分化抗原)，参与 B 细胞增殖、分化、活化及抗体产生的重要膜抗原，还可促进 BCR 的信号转导。
T79634	LYP-IN-3	Phosphatase	Metabolism
	LYP-IN-3（compound D34）作为一种淋巴酪氨酸磷酸酶（LYP）的选择性抑制剂（Ki=0.93 μM），通过调节T细胞受体（TCR）信号通路发挥在肿瘤进展中的作用。它能够激活T细胞，抑制M2型巨噬细胞的极化，并上调PD-1/PD-L1表达，适合与PD-1/PD-L1抑制剂联合使用，为癌症免疫治疗提供进一步的疗效潜力。
T76973	Tosatoxumab
	Tosatoxumab (AR-301; KBSA301) 为一种人源化免疫球蛋白G1类单克隆抗体，专一性地中和金黄色葡萄球菌α毒素(α-溶血素; Hla)，通过与该毒素N末端表位结合，防止其功能性毒素孔的寡聚化。此抗体对于金黄色葡萄球菌引起的肺炎，作为传统抗生素疗法的辅助，展现出被动免疫治疗的潜力。
T74052	Polyinosinic-polycytidylic acid potassium	Others	Others
	Polyinosinic-polycytidylic acid potassium (Poly(I:C) potassium) 是双链 RNA 的合成类似物，是一种TLR3和视黄酸诱导型基因 I 受体 (RIG-I 和MDA5) 的激动剂。Polyinosinic-polycytidylic acid potassium 可以用作疫苗佐剂，以增强先天性和适应性免疫反应，并改变肿瘤的微环境，还可以直接触发癌细胞发生凋亡 (Apoptosis)。
T75115	CD19 car circRNA-LNP	Others	Others
	CD19car circRNA-LNP是一个含CD19car circRNA的脂质纳米粒（LNP），用于RNA传递、翻译效率及细胞活力评估。CD19car circRNA适用于CAR-T细胞免疫疗法（CAR-CD19），CD19car作为一种嵌合抗原受体，而CD19是B细胞表面的CD分子，关键于B细胞的增殖、分化、激活和抗体生成，并促进BCR信号传递。
T75114	CD19 car mRNA-LNP	Others	Others
	CD19car mRNA-LNP是一种脂质纳米粒(LNP)，内含CD19car mRNA，用于RNA传递、翻译效率和细胞活力检测。该产品应用于嵌合抗原受体T细胞免疫疗法(CAR-CD19)，CD19car作为嵌合抗原受体，针对B细胞表面的CD分子（即白细胞分化抗原）CD19，该分子在B细胞增殖、分化、活化及抗体产生中发挥关键作用，并促进BCR信号转导。
T61585	Sulindac sodium	Others	Others
	Sulindac (sodium) (MK-231) 是一种非甾体抗炎剂，具有口服活性。Sulindac (sodium) 用于减轻疼痛，肿胀和关节僵硬的关节炎。Sulindac 还用于脊柱关节炎、痛风性关节炎的研究。Sulindac (sodium) 作为一种免疫调节剂，可通过阻断 NF-κB 信号通路下调 PD-L1，调节 pMMR CRC 对抗 PD-L1 免疫治疗的应答，抑制结直肠癌 CRC 的发生发展。 Sulindac 还可通过下调 SIRT1 抑制 TGF-β1-诱导的 EMT，抑制肺癌细胞的迁移和侵袭。

化合物

EP4 receptor antagonist 1

Cat.No: T11211

Target: Prostaglandin Receptor

Cat.No: T7860

Synonym: SM 324405

Target: TLR

Cat.No: T8961

Synonym: Carbamic acid

Target: MMP

Polyinosinic-polycytidylic acid sodium

Cat.No: T12516

Synonym: 双链聚肌胞,Poly(I:C) sodium

Target: Apoptosis, Others, TLR

Cat.No: T4349

Synonym: MG516,MGCD516

Target: Discoidin Domain Receptor (DDR), VEGFR, FLT, Trk receptor, TAM Receptor, c-Kit, Ephrin Receptor

Cat.No: T40350

Synonym: HPK1-IN-4

Target: MAPK

PSA1 141-150 acetate

Cat.No: TP1493L1

Synonym: PSA1 141-150 acetate(160215-60-1 free base)

Target: Others

Cat.No: T77764

Target: Others

PD-1/PD-L1-IN-16

Cat.No: T63948

Target: Others

ENPP1 inhibitor 43

Cat.No: T69560

Target: Others

Cat.No: TP2478

Synonym: Tyr-Met-Phe-Pro-agn-Ala-Pro-Tyr-Leu

Cat.No: TP1493

Synonym: PSA1 141-150

Cat.No: T82349

Cat.No: T80961

Cat.No: T82348

Cat.No: T82353

Cat.No: T83135

Synonym: hTERT (660–689)

CXCR2 antagonist 2

Cat.No: T61386

Target: Others

Cat.No: T82352

STING agonist-10

Cat.No: T63457

Target: Others

STING agonist-11

Cat.No: T63458

Target: Others

PD-1/PD-L1-IN-15

Cat.No: T63614

Target: Others

Cat.No: T82268

Synonym: BNT 316,ONC-392

Cat.No: T78852

Target: Others

Cat.No: T73186

Target: Others

Cat.No: T29413

Synonym: 3M003,3M 003

Target: Others

Cat.No: T78276

Cat.No: T75103

Target: Others

TLR7/8 agonist 9

Cat.No: T79069

Target: Others

Cat.No: T72839

Target: Others

Cat.No: T84604

Synonym: 11(S)-Hydroxyeicosatetraenoic Acid

Target: Others

CD19 CAR circRNA

Cat.No: T75104

Target: Others

Cat.No: T79634

Target: Phosphatase

Cat.No: T76973

Polyinosinic-polycytidylic acid potassium

Cat.No: T74052

Target: Others

CD19 car circRNA-LNP

Cat.No: T75115

Target: Others

CD19 car mRNA-LNP

Cat.No: T75114

Target: Others

Sulindac sodium

Cat.No: T61585

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01280	FOLR2 Protein, Human, Recombinant (His) FBP,β-HFR,FR-P3,BETA-HFR,folate receptor 2 (fetal),FR-BETA,F...	Human	HEK293 Cells
	Folate receptor beta, also known as Folate receptor 2, FBP, and FOLR2, is a member of the folate receptor family. FOLR2 is expressed in placenta and hematopoietic cells. The expression of FOLR2 is increased in malignant tissues. Members of the Folate receptor family members (FOLRs) have a high affinity for folic acid and for several reduced folic acid derivatives. They mediate the delivery of 5-methyltetrahydrofolate to the interior of, out of within, or between cells in a process known as potoc...
TMPK-01472	HLA-A24:02&B2M&MAGE-A3 (IMPKAGLLI) Tetramer Protein, Human, MHC (His & Avi) MAGE-3,CT1.3,Melanoma-associated antigen 3,MZ2D,MZ2-D,HLA-A...	Human	HEK293 Cells
	Melanoma antigen gene A3 (MAGE-A3) is one of the most immunogenic cancer testis antigens and is common in various types of cancers. MAGE-A3 can be considered as a predictor for poor prognosis and an option for vaccine immunotherapy in patients with PCa.
TMPK-01546	HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Tetramer Protein, Human, MHC (His & Avi) MHC,CT6.1,CTAG1,MY-ESO-1,ESO1CTAG,CTAG1B,NY-ESO-1,LAGE-2,LAG...	Human	HEK293 Cells
	NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses, together with its restricted expression pattern, have rendered it a good candidate target for cancer immunotherapy.
TMPK-01482	HLA-A*02:03&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi) MHC,AFPD,Alpha-fetoprotein,FETA,Alpha-1-fetoprotein,AFP,HPAF...	Human	HEK293 Cells
	Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy* targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.
TMPK-01496	HLA-A01:01&B2M&CT83 (NTDNNLAVY) Monomer Protein, Human, MHC (His & Avi) HLA-A,CT83,HLA-A0101,HLA class I,MHC class I,MHC,MHC HLA-A ...	Human	HEK293 Cells
	Cancer/testis antigens 83 (CT83), also called KK-LC-1 or CXorf61, recognized by cytotoxic T lymphocytes (CTL), has become a promising target for immunotherapy.
TMPK-01468	HLA-A*02:01&B2M&MART-1 (ELAGIGILTV) Tetramer Protein, Human, MHC (His & Avi) SK29-AA,MLANA,LB39-AA,Melan-A,MART1	Human	HEK293 Cells
	Melanoma antigen recognized by T cell-1 (Mart-1), one of the melanosome-specific proteins, also recognized by cytotoxicity T lymphocytes as a marker. Mart-1 is considered to play a critical role in the immunotherapy for melanoma.
TMPK-01494	HLA-A01:01&B2M&CT83 (NTDNNLAVY) Tetramer Protein, Human, MHC (His & Avi) HLA-A,HLA-A0101,HLA class I,MHC,MHC HLA-A alpha,CT83,MHC cl...	Human	HEK293 Cells
	Cancer/testis antigens 83 (CT83), also called KK-LC-1 or CXorf61, recognized by cytotoxic T lymphocytes (CTL), has become a promising target for immunotherapy.
TMPK-01469	HLA-A*02:01&B2M&MART-1 (ELAGIGILTV) Monomer Protein, Human, MHC (His & Avi) MLANA,SK29-AA,Melan-A,MART1,LB39-AA	Human	HEK293 Cells
	Melanoma antigen recognized by T cell-1 (Mart-1), one of the melanosome-specific proteins, also recognized by cytotoxicity T lymphocytes as a marker. Mart-1 is considered to play a critical role in the immunotherapy for melanoma.
TMPK-01543	HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Monomer Protein, Human, MHC (His & Avi) LAGE2A,ESO1CTAG,LAGE-2,CTAG1,CT6.1,MHC,MY-ESO-1,NY-ESO-1,CTA...	Human	HEK293 Cells
	NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses, together with its restricted expression pattern, have rendered it a good candidate target for cancer immunotherapy.
TMPK-01499	HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQV) Tetramer Protein, Human, MHC (His & Avi) ESO1CTAG,LAGE-2,CTAG1B,LAGE2A,MY-ESO-1,CT6.1,NY-ESO-1,CTAG1,...	Human	HEK293 Cells
	NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses, together with its restricted expression pattern, have rendered it a good candidate target for cancer immunotherapy.
TMPK-01497	HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled MY-ESO-1,MHC,ESO1CTAG,NY-ESO-1,CTAG1,LAGE2A,LAGE-2,CT6.1,CTA...	Human	HEK293 Cells
	NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses, together with its restricted expression pattern, have rendered it a good candidate target for cancer immunotherapy.
TMPK-01495	HLA-A*01:01&B2M&MAGE-A3 (EVDPIGHLY) Monomer Protein, Human, MHC (His & Avi) Melanoma-associated antigen 3,CT1.3,MZ2D,MAGE-3,MZ2-D	Human	HEK293 Cells
	Melanoma antigen gene A3 (MAGE-A3) is one of the most immunogenic cancer testis antigens and is common in various types of cancers. MAGE-A3 can be considered as a predictor for poor prognosis and an option for vaccine immunotherapy in patients with PCa.
TMPK-01521	HLA-A*02:01&B2M&AFP (PLFQVPEPV) Monomer Protein, Human, MHC (His & Avi) MHC,Alpha-feto,AFPD,Alpha-1-fetoprotein,Alpha-fetoprotein,FE...	Human	HEK293 Cells
	Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy* targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.
TMPK-01436	HLA-A*02:01&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled Alpha-1-fetoprotein,FETA,MHC,Alpha-feto,AFPD,Alpha-fetoprote...	Human	HEK293 Cells
	Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy* targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.
TMPK-01478	HLA-A*02:01&B2M&AFP (PLFQVPEPV) Monomer Protein, Human, MHC (His & Avi), Biotinylated AFP,FETA,Alpha-feto,HPAFP,Alpha-1-fetoprotein,MHC,Alpha-feto...	Human	HEK293 Cells
	Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy* targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.
TMPK-01473	HLA-A24:02&B2M&MAGE-A3 (IMPKAGLLI) Monomer Protein, Human, MHC (His & Avi), Biotinylated CT1.3,MAGE-3,MZ2-D,MZ2D,HLA-A2402,HLA-A24:02,Melanoma-assoc...	Human	HEK293 Cells
	Melanoma antigen gene A3 (MAGE-A3) is one of the most immunogenic cancer testis antigens and is common in various types of cancers. MAGE-A3 can be considered as a predictor for poor prognosis and an option for vaccine immunotherapy in patients with PCa.
TMPK-01493	HLA-A*01:01&B2M&MAGE-A3 (EVDPIGHLY) Tetramer Protein, Human, MHC (His & Avi) MZ2-D,Melanoma-associated antigen 3,MAGE-3,CT1.3,MZ2D	Human	HEK293 Cells
	Melanoma antigen gene A3 (MAGE-A3) is one of the most immunogenic cancer testis antigens and is common in various types of cancers. MAGE-A3 can be considered as a predictor for poor prognosis and an option for vaccine immunotherapy in patients with PCa.
TMPK-01474	HLA-A*24:02&B2M&MAGE-A3 (IMPKAGLLI) Monomer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	Melanoma antigen gene A3 (MAGE-A3) is one of the most immunogenic cancer testis antigens and is common in various types of cancers. MAGE-A3 can be considered as a predictor for poor prognosis and an option for vaccine immunotherapy in patients with PCa.
TMPY-05710	Der p 23 Protein, Dermatophagoides pteronyssinus, Recombinant (His) endochitinase-like,Derp 23	Dermatophagoides pteronyssinus	HEK293 Cells
	Der p 23 is a new major allergen of D. pteronyssinus. The house dust mite (HDM) Dermatophagoides pteronyssinus is one of most important allergen sources and a major elicitor of allergic asthma. Der p 23 may be an essential component for diagnosis and specific immunotherapy of HDM allergy.
TMPK-01310	Syndecan-1 Protein, Rabbit, Recombinant (His) SDC1,SYND1,SDC,CD138,Syndecan 1	Rabbit	HEK293 Cells
	CD138 (syndecan-1, Sdc-1) is a member of the syndecan family that comprises heparan sulfate proteoglycans. CD138 is significant for cell-cell and cell-matrix interactions.CD138 plays a crucial role in carcinogenesis and is an attractive target for anticancer treatment with heparanase inhibitors and anti-CD138 antibodies for immunotherapy.
TMPK-00127	CLEC4A Protein, Mouse, Recombinant (hFc) HDCGC13P,Clec4a2,DCIR,CD367,CLECSF6,DCIRLLIR,LLIR,CLEC4A,DDB...	Mouse	HEK293 Cells
	Clec4a has been reported to be an immune suppressor of dendritic cells (DCs), but its potential role in cancer therapy remains to be elucidated. silencing of Clec4a2 expression via skin delivery of shRNA produces an effective antitumor response and that Clec4a2 shRNA may have therapeutic potential as an adjuvant for cancer immunotherapy. CLEC4A Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 46.3 kDa and the accession num...
TMPK-01483	HLA-A*02:03&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi), Biotinylated AFPD,AFP,Alpha-fetoprotein,HPAFP,MHC,FETA,Alpha-1-fetoprotei...	Human	HEK293 Cells
	Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy* targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.
TMPK-01515	HLA-A*02:01&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi) HPAFP,Alpha-fetoprotein,MHC,FETA,Alpha-feto,Alpha-1-fetoprot...	Human	HEK293 Cells
	Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy* targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.
TMPK-01500	HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQV) Monomer Protein, Human, MHC (His & Avi) CTAG1,CT6.1,CTAG1B,LAGE2A,MY-ESO-1,LAGE-2,MHC,NY-ESO-1,ESO1C...	Human	HEK293 Cells
	NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses, together with its restricted expression pattern, have rendered it a good candidate target for cancer immunotherapy.
TMPK-01539	HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Monomer Protein, Human, MHC (His & Avi), Biotinylated CTAG1B,CT6.1,MY-ESO-1,LAGE2A,NY-ESO-1,MHC,LAGE-2,ESO1CTAG,CT...	Human	HEK293 Cells
	NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses, together with its restricted expression pattern, have rendered it a good candidate target for cancer immunotherapy.
TMPK-01449	HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Monomer Protein, Human, MHC (E. coli, His & Avi) MHC,CT6.1,CTAG1,LAGE-2,MY-ESO-1,NY-ESO-1,ESO1CTAG,LAGE2A,CTA...	Human	E. coli
	NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses, together with its restricted expression pattern, have rendered it a good candidate target for cancer immunotherapy.
TMPY-00025	Mammaglobin B/SCGB2A1 Protein, Human, Recombinant (hFc) UGB3,MGB2,LPNC,LPHC,LIPHC,secretoglobin family 2A member 1	Human	HEK293 Cells
	SCGB2A1 represented a novel, prognostic factor for CRC, and that expression of SCGB2A1 correlated with chemoresistance, radioresistance and cancer cell stemness. SCGB2A1 is a top differentially expressed gene in all major histological types of ovarian cancers and may represent a novel and attractive target for the immunotherapy of patients harbouring recurrent disease resistant to chemotherapy.
TMPK-01513	HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQV) Monomer Protein, Human, MHC (His & Avi), Biotinylated CT6.1,LAGE2A,MHC,CTAG1B,CTAG1,ESO1CTAG,MY-ESO-1,LAGE-2,NY-ES...	Human	HEK293 Cells
	NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses, together with its restricted expression pattern, have rendered it a good candidate target for cancer immunotherapy.
TMPK-01448	HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Tetramer Protein, Human, MHC (E. coli, His & Avi) MHC,LAGE-2,NY-ESO-1,ESO1CTAG,MY-ESO-1,CTAG1B,CTAG1,CT6.1,LAG...	Human	E. coli
	NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses, together with its restricted expression pattern, have rendered it a good candidate target for cancer immunotherapy.
TMPK-00927	ALK Protein, Mouse, Recombinant (hFc) CD246,Anaplastic lymphoma kinase,ALK tyrosine kinase recepto...	Mouse	HEK293 Cells
	Anaplastic lymphoma kinase (ALK) is mostly known for its oncogenic role in several human cancers. Recent evidences clearly indicate new roles of ALK and its genetic aberrations (e.g. gene rearrangements and mutations) in immune evasion, innate and cell-mediated immunity. New ALK-related immunotherapy approaches are demonstrating both preclinical and clinical promises.
TMPK-01477	HLA-A*02:01&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi), Biotinylated HPAFP,FETA,Alpha-1-fetoprotein,AFPD,AFP,Alpha-feto,MHC,Alpha...	Human	HEK293 Cells
	Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy* targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.
TMPK-01484	HLA-A*02:03&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi) HPAFP,FETA,AFP,AFPD,Alpha-1-fetoprotein,MHC,Alpha-fetoprotei...	Human	HEK293 Cells
	Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy* targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.
TMPK-00528	GPRC5D Protein-VLP, Cynomolgus, Recombinant MGC129713,GPRC5D,MGC129714,orphan G-protein coupled receptor	Cynomolgus	HEK293 Cells
	Chimeric antigen receptor (CAR) T cells, a type of cell-based immunotherapy, have shown some promising results in multiple myeloma, a bone marrow cancer.The orphan G protein–coupled receptor, class C group 5 member D (GPRC5D), normally expressed only in the hair follicle, Using quantitative immunofluorescence, we determined that GPRC5D protein is expressed on CD138 MM cells from primary marrow samples with a distribution that was similar to, but independent of, BCMA. GPRC5D Protein-VLP, Cynomolg...
TMPK-01519	HLA-A*02:01&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi) MHC,FETA,AFP,Alpha-feto,AFPD,Alpha-1-fetoprotein,HPAFP,Alpha...	Human	HEK293 Cells
	Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy* targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.
TMPK-01520	HLA-A*02:01&B2M&AFP (PLFQVPEPV) Tetramer Protein, Human, MHC (His & Avi) Alpha-1-fetoprotein,AFP,HPAFP,FETA,AFPD,MHC,Alpha-fetoprotei...	Human	HEK293 Cells
	Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy* targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.
TMPK-01417	HLA-A*02:03&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled Alpha-1-fetoprotein,HPAFP,AFPD,AFP,Alpha-feto,MHC,FETA,Alpha...	Human	HEK293 Cells
	Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy* targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.
TMPK-00170	CD40 Protein, Human, Recombinant (aa 21-193, His & Avi), Biotinylated CD40 antigen, TNFRSF5,CD40 molecule,CD40,MGC9013,CD40L rece...	Human	HEK293 Cells
	CD40 is a costimulatory protein found on antigen presenting cells and is required for their activation. The binding of CD154 (CD40L) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects.CD40 molecule is a potential target for cancer immunotherapy. There are number of completed and ongoing clinical trials where agonistic anti-CD40 monoclonal antibodies are employed to activate an anti-tumor T cell response via activation of dendritic cells.
TMPK-00126	CLEC4A Protein, Human, Recombinant (hFc) DCIR,LLIR,CD367,DDB27,CLECSF6,HDCGC13P,DCIRLLIR,Clec4a2,CLEC...	Human	HEK293 Cells
	Clec4a has been reported to be an immune suppressor of dendritic cells (DCs), but its potential role in cancer therapy remains to be elucidated. silencing of Clec4a2 expression via skin delivery of shRNA produces an effective antitumor response and that Clec4a2 shRNA may have therapeutic potential as an adjuvant for cancer immunotherapy. CLEC4A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 46.7 kDa and the accession num...
TMPK-01193	GPRC5D Protein-VLP, Mouse, Recombinant MGC129713,orphan G-protein coupled receptor,GPRC5D,MGC129714	Mouse	HEK293 Cells
	Chimeric antigen receptor (CAR) T cells, a type of cell-based immunotherapy, have shown some promising results in multiple myeloma, a bone marrow cancer.The orphan G protein–coupled receptor, class C group 5 member D (GPRC5D), normally expressed only in the hair follicle, Using quantitative immunofluorescence, we determined that GPRC5D protein is expressed on CD138 MM cells from primary marrow samples with a distribution that was similar to, but independent of, BCMA. GPRC5D Protein-VLP, Mouse, R...
TMPK-00809	CD37 Protein, Human, Recombinant (His) Tspan-26,GP52-40,Tetraspanin-26,MGC120234,CD37 molecule,CD37	Human	HEK293 Cells
	CD37 is a tetraspanin expressed prominently on the surface of B cells. It is an attractive molecular target exploited in the immunotherapy of B cell-derived lymphomas and leukemia. Currently, several monoclonal antibodies targeting CD37 as well as chimeric antigen receptor-based immunotherapies are being developed and investigated in clinical trials. Given the unique role of CD37 in the biology of B cells, it seems that CD37 constitutes more than a docking point for monoclonal antibodies, and ta...
TMPY-01775	AIM2 Protein, Human, Recombinant (GST) absent in melanoma 2,PYHIN4	Human	Baculovirus Insect Cells
	AIM2, Absent In Melanoma 2 is a member of the interferon-inducible HIN-200 protein family that contains an amino-terminal pyrin domain and a carboxy-terminal oligonucleotide/oligosaccharide-binding domain, senses cytoplasmic DNA by means of its oligonucleotide/oligosaccharide-binding domain and interacts with ASC (apoptosis-associated speck-like protein containing a CARD) through its pyrin domain to activate caspase-1. In response to foreign cytoplasmic DNA, AIM2 forms an inflammasome, resulting...

重组蛋白

FOLR2 Protein, Human, Recombinant (His)

Cat.No: TMPY-01280

Species: Human

Expression System: HEK293 Cells

HLA-A*24:02&B2M&MAGE-A3 (IMPKAGLLI) Tetramer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01472

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Tetramer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01546

Species: Human

Expression System: HEK293 Cells

HLA-A*02:03&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01482

Species: Human

Expression System: HEK293 Cells

HLA-A*01:01&B2M&CT83 (NTDNNLAVY) Monomer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01496

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&MART-1 (ELAGIGILTV) Tetramer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01468

Species: Human

Expression System: HEK293 Cells

HLA-A*01:01&B2M&CT83 (NTDNNLAVY) Tetramer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01494

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&MART-1 (ELAGIGILTV) Monomer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01469

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Monomer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01543

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQV) Tetramer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01499

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled

Cat.No: TMPK-01497

Species: Human

Expression System: HEK293 Cells

HLA-A*01:01&B2M&MAGE-A3 (EVDPIGHLY) Monomer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01495

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&AFP (PLFQVPEPV) Monomer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01521

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled

Cat.No: TMPK-01436

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&AFP (PLFQVPEPV) Monomer Protein, Human, MHC (His & Avi), Biotinylated

Cat.No: TMPK-01478

Species: Human

Expression System: HEK293 Cells

HLA-A*24:02&B2M&MAGE-A3 (IMPKAGLLI) Monomer Protein, Human, MHC (His & Avi), Biotinylated

Cat.No: TMPK-01473

Species: Human

Expression System: HEK293 Cells

HLA-A*01:01&B2M&MAGE-A3 (EVDPIGHLY) Tetramer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01493

Species: Human

Expression System: HEK293 Cells

HLA-A*24:02&B2M&MAGE-A3 (IMPKAGLLI) Monomer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01474

Species: Human

Expression System: HEK293 Cells

Der p 23 Protein, Dermatophagoides pteronyssinus, Recombinant (His)

Cat.No: TMPY-05710

Species: Dermatophagoides pteronyssinus

Expression System: HEK293 Cells

Syndecan-1 Protein, Rabbit, Recombinant (His)

Cat.No: TMPK-01310

Species: Rabbit

Expression System: HEK293 Cells

CLEC4A Protein, Mouse, Recombinant (hFc)

Cat.No: TMPK-00127

Species: Mouse

Expression System: HEK293 Cells

HLA-A*02:03&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi), Biotinylated

Cat.No: TMPK-01483

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01515

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQV) Monomer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01500

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Monomer Protein, Human, MHC (His & Avi), Biotinylated

Cat.No: TMPK-01539

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Monomer Protein, Human, MHC (E. coli, His & Avi)

Cat.No: TMPK-01449

Species: Human

Expression System: E. coli

Mammaglobin B/SCGB2A1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00025

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQV) Monomer Protein, Human, MHC (His & Avi), Biotinylated

Cat.No: TMPK-01513

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Tetramer Protein, Human, MHC (E. coli, His & Avi)

Cat.No: TMPK-01448

Species: Human

Expression System: E. coli

ALK Protein, Mouse, Recombinant (hFc)

Cat.No: TMPK-00927

Species: Mouse

Expression System: HEK293 Cells

HLA-A*02:01&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi), Biotinylated

Cat.No: TMPK-01477

Species: Human

Expression System: HEK293 Cells

HLA-A*02:03&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01484

Species: Human

Expression System: HEK293 Cells

GPRC5D Protein-VLP, Cynomolgus, Recombinant

Cat.No: TMPK-00528

Species: Cynomolgus

Expression System: HEK293 Cells

HLA-A*02:01&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01519

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&AFP (PLFQVPEPV) Tetramer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01520

Species: Human

Expression System: HEK293 Cells

HLA-A*02:03&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled

Cat.No: TMPK-01417

Species: Human

Expression System: HEK293 Cells

CD40 Protein, Human, Recombinant (aa 21-193, His & Avi), Biotinylated

Cat.No: TMPK-00170

Species: Human

Expression System: HEK293 Cells

CLEC4A Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00126

Species: Human

Expression System: HEK293 Cells

GPRC5D Protein-VLP, Mouse, Recombinant

Cat.No: TMPK-01193

Species: Mouse

Expression System: HEK293 Cells

CD37 Protein, Human, Recombinant (His)

Cat.No: TMPK-00809

Species: Human

Expression System: HEK293 Cells

AIM2 Protein, Human, Recombinant (GST)

Cat.No: TMPY-01775

Species: Human

Expression System: Baculovirus Insect Cells

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