h1n1

Influenza A H1N1 (A swine Belgium 1 1998) Hemagglutinin HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.9 kDa and the accession number is C9WPQ9.

Influenza A H1N1 (A swine Belgium 1 1998) Hemagglutinin HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59 kDa and the accession number is C9WPQ9.

Influenza A H1N1 (A Puerto Rico 8 34 Mount Sinai) Matrix protein 1 M1 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 29.3 kDa and the accession number is B4UPA8.

Influenza A H1N1 (A Memphis 1 1987) Hemagglutinin HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59.3 kDa and the accession number is A5GX63.

Influenza A H1N1 (A New York 1 1918) Hemagglutinin Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.5 kDa and the accession number is Q9WFX4.

Influenza A H1N1 (A Brevig Mission 1 1918) Matrix protein 1 M1 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 30 kDa and the accession number is Q8BAC3.1.

Influenza A H1N1 (A Brevig Mission 1 1918) Nucleoprotein NP Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 57.7 kDa and the accession number is Q5UEW0.1.

Influenza A H1N1 (A Brevig Mission 1 1918) Hemagglutinin HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 58.6 kDa and the accession number is Q9WFX3.

Influenza A H1N1 (A Melbourne 1 1946) Hemagglutinin HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 58.5 kDa.

Influenza A H1N1 (A Brevig Mission 1 1918) Hemagglutinin Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.5 kDa and the accession number is Q9WFX3.

Influenza A H1N1 (A Fort Monmouth 1 1947) Hemagglutinin HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59.3 kDa and the accession number is Q20MG8.

Influenza A H1N1 (A Fort Monmouth 1 1947) Hemagglutinin HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.1 kDa and the accession number is Q20MG8.

Influenza A H1N1 (A Memphis 1 1987) Hemagglutinin HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.2 kDa and the accession number is A5GX63.

Influenza A H1N1 (A swine Denmark 12813-1 2004) Hemagglutinin HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 58.5 kDa and the accession number is U5JC06.

Plays critical roles in virus replication, from virus entry and uncoating to assembly and budding of the virus particle. M1 binding to ribonucleocapsids (RNPs) in nucleus seems to inhibit viral transcription. Interaction of viral NEP with M1-RNP is thought to promote nuclear export of the complex, which is targeted to the virion assembly site at the apical plasma membrane in polarized epithelial cells. Interactions with NA and HA may bring M1, a non-raft-associated protein, into lipid rafts. Forms a continuous shell on the inner side of the lipid bilayer in virion, where it binds the RNP. During virus entry into cell, the M2 ion channel acidifies the internal virion core, inducing M1 dissociation from the RNP. M1-free RNPs are transported to the nucleus, where viral transcription and replication can take place.; Determines the virion's shape: spherical or filamentous. Clinical isolates of influenza are characterized by the presence of significant proportion of filamentous virions, whereas after multiple passage on eggs or cell culture, virions have only spherical morphology. Filamentous virions are thought to be important to infect neighboring cells, and spherical virions more suited to spread through aerosol between hosts organisms.

Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex. NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha beta pathway. Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins. It is possible that nucleoprotein binds directly host exportin-1 XPO1 and plays an active role in RNPs nuclear export. M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals. Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein. Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.

Prevents the establishment of the cellular antiviral state by inhibiting TRIM25-mediated DDX58 ubiquitination, which normally triggers the antiviral transduction signal that leads to the activation of type I IFN genes by transcription factors IRF3 and IRF7. Prevents human EIF2AK2 PKR activation, either by binding double-strand RNA, or by interacting directly with EIF2AK2 PKR. This function may be important at the very beginning of the infection, when NS1 is mainly present in the cytoplasm. Also binds poly(A) and U6 snRNA.; Inhibits post-transcriptional processing of cellular pre-mRNA, by binding and inhibiting two cellular proteins that are required for the 3'-end processing of cellular pre-mRNAs: the 30 kDa cleavage and polyadenylation specificity factor CPSF4 and the poly(A)-binding protein 2 PABPN1. In turn, unprocessed 3' end pre-mRNAs accumulate in the host nucleus and are no longer exported to the cytoplasm. Cellular protein synthesis is thereby shut off very early after virus infection. Viral protein synthesis is not affected by the inhibition of the cellular 3' end processing machinery because the poly(A) tails of viral mRNAs are produced by the viral polymerase through a stuttering mechanism.

R-Spondin 1 RSPO1 Protein, Mouse, Recombinant (His) is expressed in CHO mammalian cells with His tag. The predicted molecular weight is 28.5 kDa and the accession number is B1ASC1.

Influenza A H1N1 (A USSR 90 1977) Hemagglutinin Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.3 kDa and the accession number is P03453.

Influenza A H1N1 (A California 04 2009) Hemagglutinin HA Protein ((IQS→RQRRRRK, HA1+HA2, partially cleaved,His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 60 kDa and the accession number is C3W5S1.

Influenza A H1N1 (A Brisbane 59 2007) Hemagglutinin Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.7 kDa and the accession number is B0VX44.

Influenza A H1N1 (A New York 18 2009) Hemagglutinin HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59 kDa and the accession number is C3W6C4.

Influenza A H1N1 (A USSR 90 1977) Hemagglutinin HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59.4 kDa and the accession number is P03453.2.

Influenza A H1N1 (A Taiwan 01 1986) Hemagglutinin HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59.1 kDa and the accession number is Q1K9L3.

Influenza A H1N1 (A Mexico InDRE4114 2009) Hemagglutinin HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.7 kDa and the accession number is C5MQJ6.

Influenza A H1N1 (A Guangdong-Maonan SWL1536 2019) (A Hawaii 70 2019) Hemagglutinin HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.2 kDa and the accession number is A0A5Q2EZ09.

Influenza A H1N1 (A swine Canada 01093 2006) Neuraminidase NA Protein (HEK293, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.2 kDa and the accession number is A0A0G3XQY1.

Influenza A H1N1 (A swine Henan SN13 2018) Hemagglutinin HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.07 kDa and the accession number is A0A6G5UYK1.

Influenza A H1N1 (A swine Kansas 00246 2004) Hemagglutinin HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 58.7 kDa and the accession number is A8D6W4.

Influenza A H1N1 (A Wisconsin 67 2022) Nucleoprotein NP (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 57.49 kDa.

Influenza A H1N1 (A Wisconsin 67 2022) Neuraminidase NA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 54.34 kDa.

Influenza A H1N1 (A Sydney 5 2021) Neuraminidase NA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 54.33 kDa.

Influenza A H1N1 (A California 07 2009) Hemagglutinin HA Protein (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59 kDa and the accession number is C3W5X2.

Influenza A H1N1 (A New Caledonia 20 1999) Hemagglutinin HA-specific B cell probe (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 58 kDa and the accession number is C3W5S1.

Influenza A H1N1 (A Swine Wisconsin 136 1997) Hemagglutinin HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.8 kDa and the accession number is Q9IIJ7.

Influenza A H1N1 (A Ohio 07 2009) Hemagglutinin HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.7 kDa and the accession number is C4RUP9.

Influenza A H1N1 (A Puerto Rico 8 34 Mount Sinai) Nucleoprotein NP Protein (I116M, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 56.7 kDa and the accession number is P03466.

Influenza A H1N1 (A Beijing 22808 2009) Hemagglutinin HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.7 kDa and the accession number is D3YSI0.

Influenza A H1N1 Neuraminidase NA Protein (H275Y) is expressed in HEK293 mammalian cells. The predicted molecular weight is 47.8 kDa and the accession number is C3W5S3.

Influenza A H1N1 (A Ohio 07 2009) Hemagglutinin HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59 kDa and the accession number is C3W6H7.

Influenza A H1N1 (A Beijing 262 1995) Hemagglutinin HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59.1 kDa and the accession number is B4UPF7.

Influenza A H1N1 (A USSR 90 1977) Neuraminidase NA Protein is expressed in HEK293 mammalian cells. The predicted molecular weight is 51.9 kDa and the accession number is P03469.2.

Influenza A H1N1 (A California 04 2009) Hemagglutinin HA Protein (His), Biotinylated is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59 kDa and the accession number is C3W5S1.

Influenza A H1N1 (A Michigan 45 2015) Neuraminidase NA (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.2 kDa.

Influenza A H1N1 (A swine Denmark 19216B 1993) Neuraminidase NA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.2 kDa and the accession number is A0A0K0NHY2.

Influenza A H1N1 (A Auckland 606 2001) Neuraminidase NA (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.2 kDa and the accession number is A6M7B6.

Influenza A H1N1 (A swine Guangxi NS2176 2012) Neuraminidase NA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.5 kDa and the accession number is A0A075ESB5.

Influenza A H1N1 (A Idaho 01 2017) Neuraminidase NA (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.2 kDa and the accession number is A0A1S6GDV1.