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Search Results for " glucose-stimulated "
Targets Recommended: GPR

26

抑制剂 & 化合物

5

天然产物

13

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T27937 LY2881835

LY 2881835,LY-2881835

GPR Endocrinology/Hormones; GPCR/G Protein
LY2881835 是一种特异性 G 蛋白偶联受体 40 (GPR40) 激动剂,具有潜在的降血糖活性,可增强的葡萄糖刺激正常瘦小鼠的胰岛素分泌。LY2881835 可用于研究 2 型糖尿病。
T33412 MitoPQ

MitoParaquat

Glucokinase; transporter Metabolism
MitoPQ (MitoParaquat) 是一个线粒体靶向的小分子化合物。MitoPQ 选择性加强线粒体超氧化物和过氧化氢的含量,抑制胰岛素刺激的葡萄糖摄取和葡萄糖转运蛋白 4 (GLUT4) 向脂肪细胞和肌管中质膜的易位。MitoPQ 可用于研究线粒体氧化应激与调节的 GLUT4 转运。
T13867 RH01386

Others Others
RH01386是可以预防 ER 应激诱导的β细胞功能障碍和死亡、抑制促凋亡基因表达的小分子。它恢复内质网应激受损的葡萄糖刺激的胰岛素分泌反应。对2型糖尿病具有潜在的研究价值。
T17177 TUG-424

TUG424

Others Others
TUG-424 是一种有效且选择性的游离脂肪酸受体 1 (FFA1/GPR40) 激动剂,EC50 为 32 nM。TUG-424 在 100 nM 处显著增加葡萄糖刺激的胰岛素分泌。TUG-424 可能有助于探索 FFA1 在糖尿病或肥胖等代谢性疾病中的作用。
T12853 SBI-477

Others Others
SBI-477 是化学探针,能够使转录因子MondoA 失活,刺激胰岛素信号传导,使胰岛素途径抑制剂硫氧还蛋白相互作用蛋白和抑制蛋白结构域 4 的表达降低。它能够协调地抑制三酰基甘油酯合成,促进人骨骼肌细胞中的基础葡萄糖摄取。
TP2258 HNGF6A

Others Others
increases glucose stimulated insulin secretion and glucose metabolism
T70113 ATM-1001

Others Others
ATM-1001 is an inhibitor of the cancer-associated tropomyosin 3.1 (Tpm3.1), suppressing glucose-stimulated insulin secretion (GSIS) from the pancreatic islets.
T17094 Tifenazoxide

NN414

Others Others
Tifenazoxide is an effective and SUR1/Kir6.2 selective KATP channels opener. Tifenazoxide has an anti-diabetic effect, can inhibit glucose-stimulated insulin release in vitro and in vivo.
TP2020 [Pro3]-GIP (Mouse)

GIP receptor antagonist (IC50 = 2.6μM). Inhibits GIP-stimulated insulin release from pancreatic β cells in vitro. In ob/ob mice, blocks the effects of GIP on insulin release and plasma glucose levels. Also improves intraperitoneal glucose tolerance, insul
T62836 Hit 1

Others Others
Hit 1 是一种胰岛素降解酶 (IDE) 的激活剂 (EC50: 5.5 μM),能够降低刺激葡萄糖的胰岛素分泌。
T71251 DS-1558

Others Others
DS-1558 is a potent and orally available GPR40 agonist.DS-1558 was found to have potent glucose lowering effects during an oral glucose tolerance test in ZDF rats. DS-1558 significantly and dose-dependently improved hyperglycemia and increased insulin secretion during the oral glucose tolerance test in Zucker fatty rats, the model of insulin resistance and glucose intolerance. DS-1558 not only increased the glucose-stimulated insulin secretion by GLP-1 but also potentiated the maximum insulinog...
T75833 HNGF6A TFA

HNGF6A TFA 是一种人类素类似物。HNGF6A TFA 可以增加葡萄糖刺激的胰岛素分泌和葡萄糖代谢,并可用于糖尿病的研究。HNGF6A TFA 在氧化应激期间抑制ROS 的产生。HNGF6A TFA 可以在体内预防内皮功能障碍和动脉粥样硬化。
TP2033 [Des-His1,Glu9]-Glucagon amide

des-His1-[Glu9]-Glucagon (1-29) amide

Glucagon receptor antagonist (pA2 = 7.2 for inhibition of glucagon-induced adenylyl cyclase activation in rat liver membranes); displays no agonist activity. Enhances glucose-stimulated pancreatic insulin release in vitro. Blocks added glucagon-induced hy
T85300 Palmitoleic Acid sodium

C16:1(9Z),cis-Palmitoleic Acid,(9Z)-Hexadecenoic Acid,C16:1 n-7

Others Others
Palmitoleic acid, an ω-7 monounsaturated fatty acid found in macadamia and sea buckthorn oils, enhances both basal and insulin-stimulated glucose uptake, as well as Glut4 protein levels in 3T3-L1 adipocytes at a 200 µM concentration. Ex vivo, at a dosage of 300 mg/kg per day, it significantly increases glucose uptake and both aerobic and anaerobic glycolysis, while decreasing de novo fatty acid synthesis and the activity of lipogenic enzymes, specifically ATP citrate lyase (ACL) and glucose-6-ph...
T84407 13-PAHSA

Others Others
Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are lipids influenced by dietary changes, playing a crucial role in insulin sensitivity. These compounds typically consist of a C-16 or C-18 fatty acid (for example, palmitoleic, palmitic, oleic, or stearic acid) linked to a hydroxy fatty acid with the same carbon chain length. 13-PAHSA, a derivative where palmitic acid is esterified to 13-hydroxy stearic acid, is notably prevalent in the adipose tissue of glucose-tolerant AG4OX mice, wh...
T76326 [Des-His1,Glu9] Glucagon

[Des-His1,Glu9] Glucagon 是一种有效的胰高血糖素受体系统多肽拮抗剂。[Des-His1,Glu9] Glucagon 增强胰岛细胞在葡萄糖刺激下释放胰岛素。[Des-His1,Glu9] Glucagon 可用于糖尿病的研究。
T80766 Xenin-8 TFA

Xenin-8 TFA为Xenin的C端八肽段,同时是其生物活性片段。该化合物隶属于神经降压素/xenopsin家族多肽中。它能激发基础胰岛素的分泌并剂量依赖性地加强胰岛素对葡萄糖反应(EC50=0.16 nM)。
T35604 Osteocalcin (1-49) (human) (trifluoroacetate salt)

Osteocalcin (1-49) is a non-collagenous peptide that is secreted by osteoblasts and odontoblasts and comprises 1-2% of the total protein in bone. Secretion of osteocalcin (1-49) is stimulated by 1,25-dihydroxy vitamin D and plasma levels increase in diseases that induce dysregulated bone turnover such as osteoporosis, Paget's disease, and primary hyperparathyroidism. Osteocalcin (1-49) is positively correlated with insulin sensitivity and negatively correlated with high blood glucose levels in w...
T84567 5(S)-HEPE

Others Others
5(S)-HEPE, an active metabolite of eicosapentaenoic acid (EPA), is produced via the action of 5-lipoxygenase (5-LO). This compound functions as an agonist for G protein-coupled receptor 119 (GPR119), promoting cAMP accumulation in CHO-K1 cells expressing human GPR119 at 10 µM concentration. Additionally, 5(S)-HEPE enhances glucose-stimulated insulin secretion from MING6 insulinoma pancreatic islets and glucagon-like peptide 1 (GLP-1) secretion from HuTu 80 adenocarcinoma cells at the same concen...
T64553 GLP-1(7-37) TFA salt

Others Others
The truncated glucagon-like peptides GLP-1(7-37) is naturally occurring peptide product of the preproglucagon gene that are synthesized primarily in the intestine and acts as incretin that are released from the intestine into the bloodstream in response to food and stimulate insulin secretion. GLP-1(7-37) produced a dose-related enhancement of the glucose-stimulated increase in plasma insulin concentration and an increased rate of glucose infusion in Sprague-Dawley Rats at a dosing rang of 0.5, ...
T35854 9(Z),11(E)-Conjugated Linoleic Acid (sodium salt)

Others Others
9(Z),11(E)-Conjugated linoleic acid is an isomer of linoleic acid that has been found in beef and milk fat.1It binds to peroxisome proliferator-activated receptor α (PPARα; IC50= 140 nM) and activates the receptor in a reporter assay using COS-1 cells expressing mouse PPARα when used at a concentration of 100 μM.29(Z),11(E)-Conjugated linoleic acid inhibits TNF-α-inducedGLUT4expression and increases insulin-stimulated glucose transport in 3T3-L1 adipocytes.3Dietary administration of 9(Z)11(E)-co...
T78066 BBT

Calcium Channel Membrane transporter/Ion channel; Metabolism
BBT是一种增强剂,用于改善受损的葡萄糖刺激胰岛素分泌(GSIS)。该化合物展现出抗高血糖的活性,并能在2型糖尿病模型中,对β细胞起到保护作用,抵御细胞因子或链脲佐菌素(STZ)引起的细胞死亡。BBT的作用机制涉及通过cAMP/PKA及持久(L型)电压依赖性Ca2+通道/CaMK2通路。
T83694 Gastric Inhibitory Peptide (1-42) (porcine) TFA

GIP (1-42),Glucose-dependent Insulinotropic Polypeptide (1-42)

胃抑制肽(GIP) (1-42)是一种内源性的42氨基酸肽类肠促素激素,能诱导胰岛素分泌。该激素在肠道神经内分泌K细胞和颌下腺中表达,并在餐后释放到循环中。GIP (1-42)抑制由组胺、五肽和胰岛素引起的胃酸和胃蛋白酶分泌,增加葡萄糖诱导的胰岛素释放,并在大鼠中刺激胃排空。
T37579 GW 1929 hydrochloride

Others Others
Highly selective orally active peroxisome proliferator-activated receptor (PPAR)γ agonist (pEC50 values are 8.05, < 4 and < 4 for human PPARγ, PPARα and PPARδ receptors respectively). Decreases glucose, fatty acid and triglyceride levels following oral administration in vivo. Brown et al (1999) A novel N-aryl tyrosine activator of peroxisome proliferator-activated receptor-γ reverses the diabetic phenotype of the Zucker diabetic fatty rat. Diabetes 48 1415 PMID:10389847 |Nugent et al (2001) Pote...
T35598 Neuromedin U-25 (human) (trifluoroacetate salt)

Neuromedin U (NMU) is a neuropeptide first demonstrated to drive smooth muscle contraction.1Translated as a 174 amino acid propeptide, NMU is cleaved to different lengths in different animals. It has diverse receptor-mediated rolesin vivo, as it regulates feeding, vasoconstriction, nociception, and bone remodeling and contributes to obesity, cancer and septic shock.2,2NMU-25 is the active form of NMU in humans. It binds with high affinity to receptors on human left ventricle and coronary artery ...
T35814 Urocortin III (human) (trifluoroacetate salt)

Urocortin III is a neuropeptide hormone and member of the corticotropin-releasing factor (CRF) family which includes mammalian CRF , urocortin , urocortin II , frog sauvagine, and piscine urotensin I.1 Human urocortin III shares 90, 40, 37, and 21% identity to mouse urocortin III , mouse urocortin II , human urocortin , and mouse urocortin, respectively. Urocortin III selectively binds to type 2 CRF receptors (Kis = 21.7, 13.5, and >100 nM for rat CRF2α, rat CRF2β, and human CRF1, respectively)....

化合物

LY2881835
Cat.No: T27937
Synonym: LY 2881835,LY-2881835
Target: GPR
MitoPQ
Cat.No: T33412
Synonym: MitoParaquat
Target: Glucokinase, transporter
RH01386
Cat.No: T13867
Synonym:
Target: Others
TUG-424
Cat.No: T17177
Synonym: TUG424
Target: Others
SBI-477
Cat.No: T12853
Synonym:
Target: Others
HNGF6A
Cat.No: TP2258
Synonym:
Target: Others
ATM-1001
Cat.No: T70113
Synonym:
Target: Others
Tifenazoxide
Cat.No: T17094
Synonym: NN414
Target: Others
[Pro3]-GIP (Mouse)
Cat.No: TP2020
Synonym:
Target:
Hit 1
Cat.No: T62836
Synonym:
Target: Others
DS-1558
Cat.No: T71251
Synonym:
Target: Others
HNGF6A TFA
Cat.No: T75833
Synonym:
Target:
[Des-His1,Glu9]-Glucagon amide
Cat.No: TP2033
Synonym: des-His1-[Glu9]-Glucagon (1-29) amide
Target:
Palmitoleic Acid sodium
Cat.No: T85300
Synonym: C16:1(9Z),cis-Palmitoleic Acid,(9Z)-Hexadecenoic Acid,C16:1 n-7
Target: Others
13-PAHSA
Cat.No: T84407
Synonym:
Target: Others
[Des-His1,Glu9] Glucagon
Cat.No: T76326
Synonym:
Target:
Xenin-8 TFA
Cat.No: T80766
Synonym:
Target:
Osteocalcin (1-49) (human) (trifluoroacetate salt)
Cat.No: T35604
Synonym:
Target:
5(S)-HEPE
Cat.No: T84567
Synonym:
Target: Others
GLP-1(7-37) TFA salt
Cat.No: T64553
Synonym:
Target: Others
9(Z),11(E)-Conjugated Linoleic Acid (sodium salt)
Cat.No: T35854
Synonym:
Target: Others
BBT
Cat.No: T78066
Synonym:
Target: Calcium Channel
Gastric Inhibitory Peptide (1-42) (porcine) TFA
Cat.No: T83694
Synonym: GIP (1-42),Glucose-dependent Insulinotropic Polypeptide (1-42)
Target:
GW 1929 hydrochloride
Cat.No: T37579
Synonym:
Target: Others
Neuromedin U-25 (human) (trifluoroacetate salt)
Cat.No: T35598
Synonym:
Target:
Urocortin III (human) (trifluoroacetate salt)
Cat.No: T35814
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T1286 Vincamine

Angiopac,Oxybral,Devincan,Novicet,Equipur,长春胺,Perval

GPR; Others Endocrinology/Hormones; GPCR/G Protein; Others
Vincamine (Perval) 是从长春花中提取的单萜类吲哚生物碱,可作为外周血管扩张剂,对脑微血管循环有选择性的血管调节作用。它可改善体内葡萄糖稳态,对 2 型糖尿病具有研究潜力。它是GPR40激动剂,通过改善 β 细胞功能障碍和促进葡萄糖刺激型胰岛素分泌发挥 β 细胞保护作用。
T2755 Rhoifolin

野漆树苷,Apigenin-7-O-rhamnoglucoside,Apigenin 7-O-neohesperidoside,Rhoifoloside

Others; p38 MAPK; NF-κB; transporter; IGF-1R; Autophagy Autophagy; MAPK; Metabolism; NF-κB; Others; Tyrosine Kinase/Adaptors
Rhoifolin (Apigenin 7-O-neohesperidoside) 是从琯溪蜜柚叶子分离的一种黄酮糖苷。它通过 RANKL 诱导的NF-κB 和MAPK 途径改善钛颗粒刺激的骨溶解并减少破骨细胞生成。它通过增强脂联素分泌,胰岛素受体-β的酪氨酸磷酸化和GLUT4易位有助于治疗糖尿病并发症。
T3S0381 Chrysophanol 8-O-glucoside

Serine Protease Proteases/Proteasome
Chrysophanol 8-O-glucoside 来自Rumex acetosa 根部,具有中等的弹性蛋白酶抑制特性。它具有温和的细胞毒性和抗糖尿病特性,能够在胰岛素刺激的葡萄糖转运途径中发挥代谢作用。
TWO2727 Propane-1,2,3-triyl tripalmitate

Palmitic Triglyceride,Tripalmitin,Tripalmitoylglycerol,Glycerol Tripalmitate,三棕榈酸甘油酯

Others; Endogenous Metabolite Metabolism; Others
Propane-1,2,3-triyl tripalmitate (Glycerol Tripalmitate) 是内源性代谢产物的一种。
TN4584 Morolic acid

IL Receptor; COX; HIV Protease Immunology/Inflammation; Microbiology/Virology; Neuroscience; Proteases/Proteasome
Morolic acid and moronic acid have shown sustained antidiabetic and antihyperglycemic action possibly mediated by an insulin sensitization with consequent changes of glucose, cholesterol and triglycerides, in part mediated by inhibition of 11β-HSD 1. Moro

天然产物

Vincamine
Cat.No: T1286
Synonym: Angiopac,Oxybral,Devincan,Novicet,Equipur,长春胺,Perval
Target: GPR, Others
Rhoifolin
Cat.No: T2755
Synonym: 野漆树苷,Apigenin-7-O-rhamnoglucoside,Apigenin 7-O-neohesperidoside,Rhoifoloside
Target: Others, p38 MAPK, NF-κB, transporter, IGF-1R, Autophagy
Chrysophanol 8-O-glucoside
Cat.No: T3S0381
Synonym:
Target: Serine Protease
Propane-1,2,3-triyl tripalmitate
Cat.No: TWO2727
Synonym: Palmitic Triglyceride,Tripalmitin,Tripalmitoylglycerol,Glycerol Tripalmitate,三棕榈酸甘油酯
Target: Others, Endogenous Metabolite
Morolic acid
Cat.No: TN4584
Synonym:
Target: IL Receptor, COX, HIV Protease
Cat. No. Product Name Species Expression System
TMPY-04552 AKT1 Protein, Human, Recombinant (His)

RAC-ALPHA,v-akt murine thymoma viral oncogene homolog 1,RAC,...

Human Baculovirus Insect Cells
v-akt murine thymoma viral oncogene homolog 1 (AKT1), or protein kinase B-alpha (PKB-ALPHA) is a serine-threonine protein kinase, belonging to the Protein Kinase Superfamily. AKT1 is a major mediator of the responses to insulin, insulin-like growth factor 1 (IGF1), and glucose. AKT1 also plays a key role in the regulation of both muscle cell hypertrophy and atrophy. AKT1 activity is required for physiologic cardiac growth in response to IGF1 stimulation or exercise training. In contrast, AKT1 ac...
TMPH-01563 IAPP Protein, Human, Recombinant (His)

IAPP,Diabetes-associated peptide,Insulinoma amyloid peptide,...

Human P. pastoris (Yeast)
Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.
TMPH-02600 C1QL3 Protein, Mouse, Recombinant (His & Myc)

C1ql,Gliacolin,C1q and tumor necrosis factor-related protein...

Mouse Baculovirus Insect Cells
May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses. Plays a role in glucose homeostasis. Via AMPK signaling pathway, stimulates glucose uptake in adipocytes, myotubes and hepatocytes and enhances insulin-stimulated glucose uptake. In a hepatoma cell line, reduces the expression of gluconeogenic enzymes G6PC1 and PCK1 and hence decreases de novo glucose production.
TMPH-01562 IAPP Protein, Human, Recombinant (GST)

Insulinoma amyloid peptide,IAPP,Islet amyloid polypeptide,Am...

Human E. coli
Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism. IAPP Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 31.4 kDa and the accession number is P10997.
TMPJ-00742 GCG Protein, Human, Recombinant (His)

Glicentin,GRPP,GLP-2,Glucagon-Like Peptide 1,OXM,Glucagon,GL...

Human HEK293 Cells
Glucagon is a secreted protein and belongs to the glucagon family. Glucagon can be cleved into 8 chains, playing an important role in initiating and maintaining hyperglycemic conditions in diabetes. Glucagon can regulates blood glucose by decreasing glycolysis and increasing gluconeogenesis. In addition, Glucagon is involved in initiating and maintaining hyperglycemic conditions in diabetes. Glucagon release is stimulated by hypoglycemia and inhibited by hyperglycemia, insulin, and somatostatin....
TMPH-02677 GPI Protein, Mouse, Recombinant (B2M & His)

Gpi,Phosphohexose isomerase,Phosphoglucose isomeras...

Mouse E. coli
In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis. Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility. Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons. It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion.
TMPH-01391 GPI Protein, Human, Recombinant (His)

Sperm antigen 36,Neuroleukin,Glucose-6-phosphate is...

Human E. coli
In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis. Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility. Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons. It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion. GPI Protein, Huma...
TMPH-02678 GPI Protein, Mouse, Recombinant (His)

Phosphoglucose isomerase,Autocrine motility factor,...

Mouse P. pastoris (Yeast)
In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis. Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility. Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons. It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion. GPI Protein, Mous...
TMPH-01540 Intelectin-1/ITLN1 Protein, Human, Recombinant (His & Myc)

Galactofuranose-binding lectin,Endothelial lectin HL-1,Intel...

Human E. coli
Lectin that specifically recognizes microbial carbohydrate chains in a calcium-dependent manner. Binds to microbial glycans that contain a terminal acyclic 1,2-diol moiety, including beta-linked D-galactofuranose (beta-Galf), D-phosphoglycerol-modified glycans, D-glycero-D-talo-oct-2-ulosonic acid (KO) and 3-deoxy-D-manno-oct-2-ulosonic acid (KDO). Binds to glycans from Gram-positive and Gram-negative bacteria, including K.pneumoniae, S.pneumoniae, Y.pestis, P.mirabilis and P.vulgaris. Does not ...
TMPY-04387 AKT2 Protein, Human, Recombinant (His & GST)

RAC-β,RAC-BETA,HIHGHH,PKBBETA,PKBβ,PRKBB,PKBB,v-akt murine t...

Human Baculovirus Insect Cells
AKT (AK mouse plus Transforming or Thymoma) is a frequent oncogene expressed in most tissues which includes three isoforms AKT1, AKT2, and AKT3. Hyperactivation of AKT signaling is a central key in many human cancer progressions, through modulating angiogenesis, tumor growth, and cell migration, invasion, metastasis, and chemoresistance. Among all three isoforms, AKT2 is most related to cancer cell invasion, metastasis, and survival. Amplification and overexpression of AKT2 have been shown in ma...
TMPY-04445 PDK4 Protein, Mouse, Recombinant (His & GST)

AV005916,pyruvate dehydrogenase kinase 4

Mouse Baculovirus Insect Cells
Pyruvate dehydrogenase kinase 4 (PDK4) is a mitochondrial protein that regulates the TCA cycle.PDK4, a vital mitochondrial protein, controls the switch between glycolysis and oxidative phosphorylation based upon nutrient availability.Pyruvate dehydrogenase kinase 4 (PDK4) mRNA has been reported as an up-regulated gene in the heart and skeletal muscle of carnitine-deficient juvenile visceral steatosis (JVS) mice under fed conditions. PDK4 plays an important role in the inhibition of glucose oxida...
TMPJ-00978 PIP4K2A Protein, Human, Recombinant (His)

Diphosphoinositide kinase 2-α,PtdIns(5)P-4-kinase isoform 2-...

Human HEK293 Cells
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha (PIP4K2A) is a member of the phosphatidylinositol-4-phosphate 5-kinase family. It contains 1 PIPK domain and is expressed ubiquitously, with high levels in the brain. It catalyzes the phosphorylation of phosphatidylinositol 5-phosphate (PtdIns5P) on the fourth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). It may exert its function by regulating the levels of PtdIns5P, which functions in the...
TMPY-01960 Munc18c/STXBP3 Protein, Human, Recombinant (His & GST)

syntaxin binding protein 3,MUNC18C,UNC-18C,MUNC18-3,PSP

Human Baculovirus Insect Cells
Syntaxin-binding protein 3, also known as Platelet Sec1 protein, Protein unc-18 homolog 3, Protein unc-18 homolog C, Unc-18C, Unc18-3 and STXBP3, is a cytoplasm protein which belongs to the STXBP/unc-18/SEC1 family. STXBP3 is expressed in cells that exhibit granule exocytosis, such as neutrophils, mast cells, platelets and endothelial cells. STXBP3, together with STX4 and VAMP2, may play a role in insulin-dependent movement of GLUT4 and in docking / fusion of intracellular GLUT4-containing vesic...

重组蛋白

AKT1 Protein, Human, Recombinant (His)
Cat.No: TMPY-04552
Species: Human
Expression System: Baculovirus Insect Cells
IAPP Protein, Human, Recombinant (His)
Cat.No: TMPH-01563
Species: Human
Expression System: P. pastoris (Yeast)
C1QL3 Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02600
Species: Mouse
Expression System: Baculovirus Insect Cells
IAPP Protein, Human, Recombinant (GST)
Cat.No: TMPH-01562
Species: Human
Expression System: E. coli
GCG Protein, Human, Recombinant (His)
Cat.No: TMPJ-00742
Species: Human
Expression System: HEK293 Cells
GPI Protein, Mouse, Recombinant (B2M & His)
Cat.No: TMPH-02677
Species: Mouse
Expression System: E. coli
GPI Protein, Human, Recombinant (His)
Cat.No: TMPH-01391
Species: Human
Expression System: E. coli
GPI Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02678
Species: Mouse
Expression System: P. pastoris (Yeast)
Intelectin-1/ITLN1 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-01540
Species: Human
Expression System: E. coli
AKT2 Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04387
Species: Human
Expression System: Baculovirus Insect Cells
PDK4 Protein, Mouse, Recombinant (His & GST)
Cat.No: TMPY-04445
Species: Mouse
Expression System: Baculovirus Insect Cells
PIP4K2A Protein, Human, Recombinant (His)
Cat.No: TMPJ-00978
Species: Human
Expression System: HEK293 Cells
Munc18c/STXBP3 Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-01960
Species: Human
Expression System: Baculovirus Insect Cells
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