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Search Results for " folic acid "

Targets Recommended: Others

51

抑制剂 & 化合物

13

天然产物

4

重组蛋白

3

同位素标记化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T32075	HH-Folic acid	Others	Others
	HH-Folic acid derives from vitamin B9.
T31838	Folic acid, methyl- x-Methylfolic acid,x-Methyl folic acid,x-Methylpteroylglutamic acid	Others	Others
	Folic acid, methyl- is a nutrient that belongs to the vitamin B family. Folate is significant for the easy conversion of carbohydrates into glucose and is essential in red blood cell formation, cell division, detoxification, and the production of some neu
T0699	Sulfamonomethoxine 磺胺间甲氧嘧啶,磺胺间甲氧嘧啶钠	Antibacterial; Antibiotic	Microbiology/Virology
	Sulfamonomethoxine 是一种磺胺类抗菌剂。它可研究血液动力学，竞争性抑制剂二氢叶酸合成，从而阻断叶酸合成。
T84718	Folic acid disodium Vitamin B9 disodium,Vitamin M disodium	Others	Others
	Folic acid disodium，Folic acid的口服活性钠盐形式，具有固有溶出速率（IDR）为4.96·105g/s。它作为单碳转移反应中的辅助因子，有助于防治神经管缺陷、缺血和癌症。Folic acid disodium的过量可能会损害胚胎大脑发展并促进癌前细胞变化的增长；而其缺乏则可能导致巨幼细胞性贫血。
T25999	Pteropterin Teropterin,PTGA,Pteroyl triglutamic acid,Folic acid diglutamate	Others	Others
	Pteropterin is an antineoplastic agent.
T0849	Pyrimethamine Pirimecidan,RP 4753,Pirimetamin,乙胺嘧啶	DHFR; Antifolate; Parasite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology
	Pyrimethamine (Pirimecidan) 是一种二氢叶酸还原酶的竞争性抑制剂，用作抗疟药。
T16045	Methotrexate metabolite DAMPA,甲喋呤杂质E	Antifolate; Drug Metabolite	Cell Cycle/Checkpoint; Metabolism
	Methotrexate metabolite (DAMPA) (DAMPA)是 Methotrexate 的活性代谢物。Methotrexate 具有拮抗叶酸 (folic acid) 的作用，被用作免疫抑制剂。
T20882	4-Nitrobenzoic acid Kyselina p-nitrobenzoova,4Nitrobenzoic acid,Nitrodracylic acid,4 Nitrobenzoic acid
	4-Nitrobenzoic acid (4Nitrobenzoic acid) 是一种药物中间体，常在叶酸、DABA、PABA 和染料的生产中出现。
T20339	7-Hydroxymethotrexate NSC 380963,NSC-380963,NSC380962,NSC380963,NSC 380962,NSC-380962	Drug Metabolite	Metabolism
	7-Hydroxymethotrexate 是 Methotrexate 主要的代谢产物。Methotrexate 对叶酸具有抑制作用，抑制二氢叶酸还原酶，从而防止叶酸转化为四氢叶酸，并抑制 DNA 合成。Methotrexate 对代谢也具有抑制作用。
T0148L	Folinic Acid Calcium Salt Pentahydrate Folinic acid,亚叶酸钙五水合物,Leucovorin Calcium Pentahydrate,Leucovorin calcium salt pentahydrate	Others; Antifolate	Cell Cycle/Checkpoint; Others
	Folinic Acid Calcium Salt Pentahydrate (Leucovorin Calcium Pentahydrate) 是一种还原型叶酸，是一种解毒剂，通常与甲氨蝶呤 (MTX) 联用，以降低 MTX 诱导的毒性。
T7593	Levomefolate calcium 左旋甲状腺素钙,L-5-甲基四氢叶酸钙	Antifolate	Cell Cycle/Checkpoint
	Levomefolate calcium 是一种人工形式的叶酸。它是叶酸的一种辅酶形式，是膳食补充剂中生物利用度更高的替代品。
T0930	Sulfadiazine Sulphadiazine,磺胺嘧啶	Antibacterial; Antibiotic; Parasite; Autophagy	Autophagy; Microbiology/Virology
	Sulfadiazine (Sulphadiazine) 是一种磺胺类抗生素具有抗疟活性，可研究弓形虫病。
T21434	Sulfacetamide NSC 63871,磺胺醋酰,NSC-63871,Sebizon,Region,NSC63871,Sulphacetamide,Acetosulfamine	Others; Antibacterial; Antibiotic	Microbiology/Virology; Others
	Sulfacetamide (NSC-63871) 是一种抗生素，通过限制细菌生存所需的叶酸的存在来治疗睑缘炎或结膜炎，有潜力用于眼部感染的研究。
T32100	Homofolic acid NSC-79249,NSC 79249,9-Methylfolic acid,NSC79249,Homofolate	Others	Others
	Homofolic acid is a folic acid analog.
T31508	Diopterin Folate monoglutamate,Pteroyl diglutamic acid	Others	Others
	Diopterin is a folic acid analog.
T33691	Nitrosofolic acid CCRIS 466,N-Nitrosofolic acid,Glutamic acid, N-nitroso-N-pteroyl-, L-	Others	Others
	Nitrosofolic acid is a folic acid derivaive.
T68629	Lysine-iodoacetylmethotrexate	Others	Others
	Lysine-iodoacetylmethotrexate if a Folic Acid Antagonist.
T34822	Tetrahydromethotrexate NSC 526044,NSC-526044,NSC526044	Others	Others
	Tetrahydromethotrexate is a folic acid derivative.
T34183	Pteroylpentaglutamic acid Pte-penta-glu,NSC372667,NSC 372667,NSC-372667	Others	Others
	Pteroylpentaglutamic acid within the folic acid family is a bioactive chemical.
T24972	2'-Fluoroaminopterin	Others	Others
	2'-Fluoroaminopterin is a folic acid antagonist agent.
T24976	3'-Fluoroaminopterin	Others	Others
	3'-Fluoroaminopterin is a folic acid antagonist agent.
T24535	Ninopterin NSC-107137,NSC107137,9-Me-PGA,NSC 107137,L-Glutamic acid, 9-methylpteroyl-	Others	Others
	Ninopterin is an experimental antineoplastic and folic acid analog.
T11144	EC0488	Others	Others
	EC0488 was used to synthesize EC0531, which has folic acid receptor specificity and anti-tumor activity.
T31851	Formiminoglutamic acid NSC-334078,NSC334078,NSC 334078	Others	Others
	Formiminoglutamic acid is used to indicate folic acid deficiency and megaloblastic anemia of pregnancy with the measurement in the urine after oral administration of histidine.
T24961	10-Deazaaminopterin NSC 311469,NSC-311469,10-Deaza-aminopterin,NSC311469	Others	Others
	10-Deazaaminopterin is a poly-gamma-glutamyl metabolite of the experimental anticancer drug, a folic acid antagonist, antineoplastic agent enzyme inhibitor.
T30690	Calcium dextrofolinate Calcium (6R)-folinate	Others	Others
	Calcium dextrofolinate is a calcium salt of a derivative of Folic Acid.
T25208	CB 3717 CB3717,CB-3717,N(sup 10)-Propargyl-5,8-dideazafolic acid	Others	Others
	CB 3717 is an enzyme inhibitor, antineoplastic agent, folic acid antagonist.
T32706	Levomefolate calcium pentahydrate	Others	Others
	Levomefolate calcium pentahydrate is the calcium salt of 5-methyltetrahydrofolic acid, a biologically active form of folic acid that functions, in conjunction with Vitamin B12. Levomefolate is included in formulations of certain oral contraceptives to ens
T29461	5-Methyltetrahydrofolate triglutamate 5-Me-Thf(glu)3	Others	Others
	5-Methyltetrahydrofolate triglutamate is a form of folic acid.
T29434	4-Desacetylvinblastine hydrazide DAVLBH,Deacetylvinblastine hydrazide,Desacetylvinblastine hydrazide	Others	Others
	Deacetylvinblastine hydrazide, a cytotoxic vinca alkaloid often conjugated with folic acid to produce EC145, a novel folate-receptor targeted agent.
T25796	Methotrexate 1-methyl ester Methotrexate related compound I,Methotrexate alpha-methyl ester	Others	Others
	Methotrexate 1-methyl ester is an impurity of Methotrexate which is a folic acid antagonist. It's used as an antineoplastic and antirheumatic.
T70080	Methasquin	Others	Others
	Methasquin is a folic acid antagonist that has been used in the treatment of experimental leukemia; acts by inhibiting the dihydrofolate reductase in the cell.
T25797	Methotrexate 5-methyl ester	Others	Others
	Methotrexate 5-methyl ester is an impurity of Methotrexate which is a folic acid antagonist. It's used as an antineoplastic and antirheumatic.
T34740	Sulfacytine Renoquid,CI636,CI-636,CI 636,磺胺西汀,Sulfacitinum	Others	Others
	Sulfacytine is a short-acting sulfonamides antibiotic that is taken orally to treat bacterial infections. Sulfonamides, a group of antibiotics, work by inhibiting bacterial production of folic acid.
T25358	EC-17 free acid EC17,EC 17,EC-17,FTIC-Folate,Folate-FTIC	Others	Others
	EC17 is a FITC conjugated folic acid, also known as Folate-FITC. It also acts as an FRα-targeting agent that fluoresces at 500nm. EC17 is a conjugate consisting of fluorescein isothiocyanate (FITC) conjugated with folate with potential antineoplastic acti
T13672	EC0489	Others	Others
	EC0489, Small molecule-drug conjugate (SMDC) ,a conjugate of folic acid and desacetyl vinblastine hydrazide, is a high-affinity ligand for the folate receptor (FR). Refractory or metastatic Tumor.
T32705	Levomefolate magnesium L-Methylfolate magnesium	Others	Others
	Levomefolate magnesium is the magnesium salt of the metabolite of folic acid (Vitamin B9) and it is a predominant active form of folate found in foods and in the blood circulation, accounting for 98% of folates in human plasma. It is transported across th
T37998	N-(4-Aminobenzoyl)-L-glutamic Acid (hydrate)	Others	Others
	N-(4-Aminobenzoyl)-L-glutamic acid is an oxidation product and a metabolite of tetrahydrofolate.1Levels of N-(4-aminobenzoyl)-L-glutamic acid are increased in the plasma of mice fed a high folic acid-containing diet.2 1.Reed, L.S., and Archer, M.C.Oxidation of tetrahydrofolic acid by airJ. Agric. Food Chem.28(4)801-805(1980) 2.Burton, M.A., Antoun, E., Penailillo, R.S., et al.Folic acid induces intake-related changes in the mammary tissue transcriptome of C57BL/6 miceNutrients12(9)2821(2020)
T78233	Sulfamonomethoxine sodium	Antibiotic	Microbiology/Virology
	Sulfamonomethoxine sodium用作血液动力学研究中的竞争性抑制剂，通过抑制二氢叶酸合成，进而阻断叶酸的生成。
T63985	Trimetrexate glucuronate	Others	Others
	Trimetrexate glucuronate (NSC 352122) 是一种叶酸拮抗剂，能够抑制二氢叶酸还原酶 (dihydrofolate reductase)，进而阻断嘌呤核苷酸和胸苷酸的合成，影响 DNA 和 RNA 合成，表现出潜在的抗肿瘤效果。
T25496	Hexaglutamate folate Pteglu6	Others	Others
	Hexaglutamate folate is a naturally occurring form of folic acid. The bioavailability of dietary folate may be limited by the need for the glutamate moieties to be deconjugated before absorption. Folate deficiency in humans results in anemia, neural tube
T74009	1,1,3-Tribromoacetone	Others	Others
	1,1,3-Tribromoacetone 是甲氨蝶呤的杂质。Methotrexate (Amethopterin) 是一种抗代谢 (antimetabolite) 和抗叶酸剂 (antifolate)，可抑制二氢叶酸还原酶，从而防止叶酸转化为四氢叶酸并抑制 DNA 合成。
T69089	Trimethoprim sulfate	Others	Others
	Trimethoprim sulfate is a pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. The interference with folic acid metabolism may cause a depression of hematopoiesis. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM-SULFAMETHOXAZOLE COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
T35413	(6R,S)-5,6,7,8-Tetrahydrofolic Acid (hydrochloride)	Others	Others
	(6R,S)-5,6,7,8-Tetrahydrofolic acid (THFA), the reduced form of folic acid, serves as a cofactor in methyltransferase reactions and is the major one-carbon carrier in one carbon metabolism. Its metabolites participate in the synthesis of thymidine for incorporation into DNA or the synthesis of purines, as well as in the formation of methionine, which can be converted to the ubiquitous methyl donor, S-adenosylmethionine . THFA has also been used to study the activation of metabolite-binding ribos...
T77274	DSPE-PEG-Folate (MW 5000)	Others	Others
	DSPE-PEG-Folate (MW 5000) 是一种含叶酸的 PEG 衍生物，能与癌细胞的叶酸受体结合并具有靶向作用。该化合物可形成胶束/脂质双层，适用于靶向给药系统的研究。
T68232	Epofolate	Others	Others
	Epofolate is folate receptor-targeting antimitotic agent with potential antineoplastic activity. Folate receptor-targeted epothilone BMS753493 contains an epothilone moiety linked to a single folate molecule. Mediated through the folate moiety, this agent delivers the antimitotic epothilone component into cells expressing folic acid receptors, frequently upregulated in many types of tumor cells. After ligand-receptor internalization, the epothilone moiety induces microtubule polymerization and s...
T74308	DSPE-PEG-Folate	Others	Others
	DSPE-PEG-Folate (Mw 3350) 是一种含有叶酸的 PEG 衍生物。DSPE-PEG-Folate 具有靶向作用并能与癌细胞中的叶酸受体结合。DSPE-PEG-Folate 形成胶束/脂质双层，可用于靶向给药系统的研究。
T84853	PEG-bis-amine (MW 1000) Poly(ethylene glycol)-bis-amine (MW 1000)	Others	Others
	PEG-bis-amine (MW 1000) 可用于合成叶酸缀合聚合物胶束，进而封装抗癌药物9-硝基喜树碱。该叶酸缀合聚合物胶束作为难溶性抗癌药物的高效载体，不仅能有效避免巨噬细胞的清除，同时利用叶酸受体（FR）介导的靶向机制，促使药物被肿瘤细胞内吞，从而发挥抗癌作用。
T79632	Antileishmanial agent-21	Parasite	Microbiology/Virology
	Antileishmanial agent-21 (compound 4e)，是靶向利什曼原虫蝶啶还原酶1 (Lm-PTR1) 的抗利什曼虫试剂。该化合物通过抗叶酸机制发挥作用，且其抗利什曼活性能被叶酸和亚叶酸逆转。Antileishmanial agent-21 还能抑制对 Chloroquine 抗性的恶性疟原虫菌株 (RKL9)，IC50 范围为0.0198-0.096 μM。
T84850	PEG-bis-amine (MW 8000) Poly(ethylene glycol)-bis-amine (MW 8000)	Others	Others
	PEG-bis-amine (MW 8000) 作为合成物，可用于制备叶酸缀合的聚合物胶束，进而包裹抗癌药物9-硝基喜树碱。这种叶酸缀合聚合物胶束作为难溶性抗癌药物的高效载体，具备绕过巨噬细胞的能力，并能够通过叶酸受体（FR）介导的方式，实现对肿瘤细胞的靶向性内吞作用。

化合物

HH-Folic acid

Cat.No: T32075

Target: Others

Folic acid, methyl-

Cat.No: T31838

Synonym: x-Methylfolic acid,x-Methyl folic acid,x-Methylpteroylglutamic acid

Target: Others

Sulfamonomethoxine

Cat.No: T0699

Synonym: 磺胺间甲氧嘧啶,磺胺间甲氧嘧啶钠

Target: Antibacterial, Antibiotic

Folic acid disodium

Cat.No: T84718

Synonym: Vitamin B9 disodium,Vitamin M disodium

Target: Others

Cat.No: T25999

Synonym: Teropterin,PTGA,Pteroyl triglutamic acid,Folic acid diglutamate

Target: Others

Cat.No: T0849

Synonym: Pirimecidan,RP 4753,Pirimetamin,乙胺嘧啶

Target: DHFR, Antifolate, Parasite

Methotrexate metabolite

Cat.No: T16045

Synonym: DAMPA,甲喋呤杂质E

Target: Antifolate, Drug Metabolite

4-Nitrobenzoic acid

Cat.No: T20882

Synonym: Kyselina p-nitrobenzoova,4Nitrobenzoic acid,Nitrodracylic acid,4 Nitrobenzoic acid

7-Hydroxymethotrexate

Cat.No: T20339

Synonym: NSC 380963,NSC-380963,NSC380962,NSC380963,NSC 380962,NSC-380962

Target: Drug Metabolite

Folinic Acid Calcium Salt Pentahydrate

Cat.No: T0148L

Synonym: Folinic acid,亚叶酸钙五水合物,Leucovorin Calcium Pentahydrate,Leucovorin calcium salt pentahydrate

Target: Others, Antifolate

Levomefolate calcium

Cat.No: T7593

Synonym: 左旋甲状腺素钙,L-5-甲基四氢叶酸钙

Target: Antifolate

Cat.No: T0930

Synonym: Sulphadiazine,磺胺嘧啶

Target: Antibacterial, Antibiotic, Parasite, Autophagy

Cat.No: T21434

Synonym: NSC 63871,磺胺醋酰,NSC-63871,Sebizon,Region,NSC63871,Sulphacetamide,Acetosulfamine

Target: Others, Antibacterial, Antibiotic

Homofolic acid

Cat.No: T32100

Synonym: NSC-79249,NSC 79249,9-Methylfolic acid,NSC79249,Homofolate

Target: Others

Cat.No: T31508

Synonym: Folate monoglutamate,Pteroyl diglutamic acid

Target: Others

Nitrosofolic acid

Cat.No: T33691

Synonym: CCRIS 466,N-Nitrosofolic acid,Glutamic acid, N-nitroso-N-pteroyl-, L-

Target: Others

Lysine-iodoacetylmethotrexate

Cat.No: T68629

Target: Others

Tetrahydromethotrexate

Cat.No: T34822

Synonym: NSC 526044,NSC-526044,NSC526044

Target: Others

Pteroylpentaglutamic acid

Cat.No: T34183

Synonym: Pte-penta-glu,NSC372667,NSC 372667,NSC-372667

Target: Others

2'-Fluoroaminopterin

Cat.No: T24972

Target: Others

3'-Fluoroaminopterin

Cat.No: T24976

Target: Others

Cat.No: T24535

Synonym: NSC-107137,NSC107137,9-Me-PGA,NSC 107137,L-Glutamic acid, 9-methylpteroyl-

Target: Others

Cat.No: T11144

Target: Others

Formiminoglutamic acid

Cat.No: T31851

Synonym: NSC-334078,NSC334078,NSC 334078

Target: Others

10-Deazaaminopterin

Cat.No: T24961

Synonym: NSC 311469,NSC-311469,10-Deaza-aminopterin,NSC311469

Target: Others

Calcium dextrofolinate

Cat.No: T30690

Synonym: Calcium (6R)-folinate

Target: Others

Cat.No: T25208

Synonym: CB3717,CB-3717,N(sup 10)-Propargyl-5,8-dideazafolic acid

Target: Others

Levomefolate calcium pentahydrate

Cat.No: T32706

Target: Others

5-Methyltetrahydrofolate triglutamate

Cat.No: T29461

Synonym: 5-Me-Thf(glu)3

Target: Others

4-Desacetylvinblastine hydrazide

Cat.No: T29434

Synonym: DAVLBH,Deacetylvinblastine hydrazide,Desacetylvinblastine hydrazide

Target: Others

Methotrexate 1-methyl ester

Cat.No: T25796

Synonym: Methotrexate related compound I,Methotrexate alpha-methyl ester

Target: Others

Cat.No: T70080

Target: Others

Methotrexate 5-methyl ester

Cat.No: T25797

Target: Others

Cat.No: T34740

Synonym: Renoquid,CI636,CI-636,CI 636,磺胺西汀,Sulfacitinum

Target: Others

EC-17 free acid

Cat.No: T25358

Synonym: EC17,EC 17,EC-17,FTIC-Folate,Folate-FTIC

Target: Others

Cat.No: T13672

Target: Others

Levomefolate magnesium

Cat.No: T32705

Synonym: L-Methylfolate magnesium

Target: Others

N-(4-Aminobenzoyl)-L-glutamic Acid (hydrate)

Cat.No: T37998

Target: Others

Sulfamonomethoxine sodium

Cat.No: T78233

Target: Antibiotic

Trimetrexate glucuronate

Cat.No: T63985

Target: Others

Hexaglutamate folate

Cat.No: T25496

Synonym: Pteglu6

Target: Others

1,1,3-Tribromoacetone

Cat.No: T74009

Target: Others

Trimethoprim sulfate

Cat.No: T69089

Target: Others

(6R,S)-5,6,7,8-Tetrahydrofolic Acid (hydrochloride)

Cat.No: T35413

Target: Others

DSPE-PEG-Folate (MW 5000)

Cat.No: T77274

Target: Others

Cat.No: T68232

Target: Others

DSPE-PEG-Folate

Cat.No: T74308

Target: Others

PEG-bis-amine (MW 1000)

Cat.No: T84853

Synonym: Poly(ethylene glycol)-bis-amine (MW 1000)

Target: Others

Antileishmanial agent-21

Cat.No: T79632

Target: Parasite

PEG-bis-amine (MW 8000)

Cat.No: T84850

Synonym: Poly(ethylene glycol)-bis-amine (MW 8000)

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T0062	Folic acid Folate,Vitamin B9,Pteroylglutamic acid,Vitamin M,叶酸,Folacin	DNA/RNA Synthesis; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	Folic acid (Vitamin B9) 是维生素B9，是合成DNA/RNA，新细胞产生和维持的必要成分。
T7730	Aminopterin APGA,氨基蝶呤,4-Aminofolic acid	Antifolate	Cell Cycle/Checkpoint
	Aminopterin (4-Aminofolic acid) 是叶酸的 4-氨基衍生物，是叶酸拮抗剂，具有抗癌和免疫抑制活性，用于研究儿童白血病。它催化叶酸还原为四氢叶酸，竞争性抑制二氢叶酸还原酶，Ki 值为 3.7 pM。
T7094	Levomefolic Acid L-5-甲基四氢叶酸,5-MTHF,5-甲基四氢叶酸	Reactive Oxygen Species; Endogenous Metabolite	Immunology/Inflammation; Metabolism; NF-κB
	Levomefolic Acid (5-MTHF) 是一种具有口服活性、可穿过血脑屏障的天然活性叶酸，是广泛使用的叶酸食品补充剂。
T31836	Folate sodium Folic acid, monosodium salt,Folvite sodium
	Folate sodium, as a member of the vitamin B family, can stimulate the hematopoietic system. Folic acid can be used in the treatment and prevention of folate deficiencies and megaloblastic anemia.
T0148	Folinic acid calcium 亚叶酸钙,Wellcovorin,Calcium folinate,Leucovorin Calcium,Folinic acid calcium salt	DNA/RNA Synthesis; Endogenous Metabolite; Antifolate	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	Folinic acid calcium (Leucovorin Calcium) 是叶酸的活性代谢物，是一种解毒剂，通常与甲氨蝶呤 (MTX) 联用，以降低 MTX 诱导的毒性。
T8854	PTEROIC ACID	Others	Others
	PTEROIC ACID 是叶酸结构的一部分
T13516	5-Methyltetrahydrofolic acid 甲基叶酸盐,5-Methyl THF	Endogenous Metabolite	Metabolism
	5-Methyltetrahydrofolic acid (5-Methyl THF) 是四氢叶酸的甲基化衍生物，具有生物活性。5-Methyltetrahydrofolic acid 是主要的天然膳食叶酸，是血浆和脑脊液中叶酸的主要形式。
TN6988	Pterine-6-carboxylic acid 6-Carboxypterin	DNA; PDE	DNA Damage/DNA Repair; Metabolism
	Pterine-6-carboxylic acid (6-Carboxypterin) 是叶酸的光降解产物，可被用作光敏感剂研究UVA 破环DNA 结构的分子机制。
T1040	Vitamin B12 Cyanocobalamin,Cobalamin,维生素B12	Endogenous Metabolite	Metabolism
	Vitamin B12 (Cobalamin) 是一种维生素，在维持血流形成和脑、神经系统正常功能等方面发挥关键作用。
T13969	Xanthopterin (hydrate)	Others; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Others
	Xanthopterin hydrate 是东方大黄蜂翅膀中黄色颗粒的主要成分，是一种非共轭的蝶啶天然产物，在 386/456 nm 处产生特征性的激发光。它可抑制 RNA 合成，引起大鼠肾脏生长和肥大。
T4877	L-Homocystine	Endogenous Metabolite	Metabolism
	L-Homocystine 是一种 L-homocysteine 的氧化物。其中 L-homocysteine 是抗血栓因子、血管舒张损害剂、促炎因子，也是研究心血管疾病发生机制的内质网应激反应的诱导剂。
T29477	6R-Leucovorin (6R,2'S)-Folinic acid,Dextrofolinic acid
	6R-Leucovorin is a derivative of Folic Acid.
T15128	Dihydrofolic acid 7,8-Dihydrofolic acid,Dihydrofolate	Others	Others
	Dihydrofolic acid (7,8-Dihydrofolic acid) 是一种叶酸衍生物，在二氢叶酸还原酶的作用下生成四氢叶酸。

天然产物

Cat.No: T0062

Synonym: Folate,Vitamin B9,Pteroylglutamic acid,Vitamin M,叶酸,Folacin

Target: DNA/RNA Synthesis, Endogenous Metabolite

Cat.No: T7730

Synonym: APGA,氨基蝶呤,4-Aminofolic acid

Target: Antifolate

Levomefolic Acid

Cat.No: T7094

Synonym: L-5-甲基四氢叶酸,5-MTHF,5-甲基四氢叶酸

Target: Reactive Oxygen Species, Endogenous Metabolite

Cat.No: T31836

Synonym: Folic acid, monosodium salt,Folvite sodium

Folinic acid calcium

Cat.No: T0148

Synonym: 亚叶酸钙,Wellcovorin,Calcium folinate,Leucovorin Calcium,Folinic acid calcium salt

Target: DNA/RNA Synthesis, Endogenous Metabolite, Antifolate

Cat.No: T8854

Target: Others

5-Methyltetrahydrofolic acid

Cat.No: T13516

Synonym: 甲基叶酸盐,5-Methyl THF

Target: Endogenous Metabolite

Pterine-6-carboxylic acid

Cat.No: TN6988

Synonym: 6-Carboxypterin

Target: DNA, PDE

Cat.No: T1040

Synonym: Cyanocobalamin,Cobalamin,维生素B12

Target: Endogenous Metabolite

Xanthopterin (hydrate)

Cat.No: T13969

Target: Others, DNA/RNA Synthesis

Cat.No: T4877

Target: Endogenous Metabolite

Cat.No: T29477

Synonym: (6R,2'S)-Folinic acid,Dextrofolinic acid

Dihydrofolic acid

Cat.No: T15128

Synonym: 7,8-Dihydrofolic acid,Dihydrofolate

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01280	FOLR2 Protein, Human, Recombinant (His) FBP,β-HFR,FR-P3,BETA-HFR,folate receptor 2 (fetal),FR-BETA,F...	Human	HEK293 Cells
	Folate receptor beta, also known as Folate receptor 2, FBP, and FOLR2, is a member of the folate receptor family. FOLR2 is expressed in placenta and hematopoietic cells. The expression of FOLR2 is increased in malignant tissues. Members of the Folate receptor family members (FOLRs) have a high affinity for folic acid and for several reduced folic acid derivatives. They mediate the delivery of 5-methyltetrahydrofolate to the interior of, out of within, or between cells in a process known as potoc...
TMPK-00150	FOLR1 Protein, Human, Recombinant (His & Avi) Folate receptor 1,Folbp1,Folate receptor alpha,FR-alpha,FR a...	Human	HEK293 Cells
	Folate Receptor 1 (FOLR1), also known as Folate Receptor alpha and Folate Binding Protein (FBP), is a 37 - 42 kDa protein that mediates the cellular uptake of folic acid and reduced folates. Dietary folates are required for many key metabolic processes including nucleotide and methionine synthesis, the interconversion of glycine and serine, and histidine breakdown. FOLR1 binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into t...
TMPK-00878	FOLR3 Protein, Human, Recombinant (His) FR-γ,Folate receptor 3,FR-gamma,FR-G	Human	HEK293 Cells
	Folic acid and folate receptors (FOLRs) play an important role in the downregulation of homocysteine (Hcy), a risk factor of Alzheimer's disease, thrombosis, neuropsychiatric illness and fractures.
TMPJ-00055	Podoplanin Protein, Mouse, Recombinant (hFc) T1-alpha,PA2.26 antigen,T1A,Podoplanin,T1-α,Glycoprotein 38,...	Mouse	HEK293 Cells
	Podoplanin belongs to the podoplanin family, also known as Glycoprotein 38. Podoplanin is synthesized as a 172 amino acid (aa) precursor with a 22 aa signal sequence, a 119 aa extracellular domain (ECD), a 21 aa transmembrane region, and a short, 10 aa cytoplasmic tail. Detected at high levels in lung and brain, at lower levels in kidney, stomach, liver, spleen and esophagus, and not detected in skin and small intestine. Expressed in epithelial cells of choroid plexus, ependyma, glomerulus and ...

重组蛋白

FOLR2 Protein, Human, Recombinant (His)

Cat.No: TMPY-01280

Species: Human

Expression System: HEK293 Cells

FOLR1 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00150

Species: Human

Expression System: HEK293 Cells

FOLR3 Protein, Human, Recombinant (His)

Cat.No: TMPK-00878

Species: Human

Expression System: HEK293 Cells

Podoplanin Protein, Mouse, Recombinant (hFc)

Cat.No: TMPJ-00055

Species: Mouse

Expression System: HEK293 Cells

Cat. No.	Product Name	Target	Signaling Pathways
TMIH-0243	Folic Acid-d4
	Folic Acid-d4 是 Folic Acid 的氘代化合物。
T13032	Sulfamonomethoxine-d4	Others	Others
	Sulfamonomethoxine D4 is a deuterium labeled Sulfamonomethoxine. Sulfamonomethoxine is an agent of long acting sulfonamide antibacterial, used in blood kinetic studies,and blocks the synthesis of folic acid by inhibiting synthetase of dihydropteroate.
TMIJ-0375	Levomefolic Acid-13C-d3
	Levomefolic Acid-13C-d3 是 Levomefolic Acid 的 13C 和氘代化合物。Levomefolic Acid 的 CAS 号为 31690-09-2。Levomefolic acid是一种具有口服活性、可穿过血脑屏障的天然活性叶酸，是广泛使用的叶酸食品补充剂。

同位素标记化合物

Folic Acid-d4

Cat.No: TMIH-0243

Sulfamonomethoxine-d4

Cat.No: T13032

Target: Others

Levomefolic Acid-13C-d3

Cat.No: TMIJ-0375

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