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Search Results for " fibrin "

Targets Recommended: Others

34

抑制剂 & 化合物

2

天然产物

1

化合物库

21

重组蛋白

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Cat. No.	Product Name
L7500	凝血与抗凝化合物库		144 compounds
	144 个化合物的独特集合，可用于高通量筛选和高内涵筛选；

化合物库

凝血与抗凝化合物库

Cat.No: L7500

Compounds: 144

Cat. No.	Product Name	Target	Signaling Pathways
T78562	FX-06 Fibrin-derived peptide Bβ15-42	Others	Others
	FX-06 (Fibrin-derived peptide Bβ15-42)为纤维蛋白Bbeta链衍生的肽类化合物。通过与VE-cadherin结合并阻断白细胞的迁移，FX-06激活了以VE-cadherin为中心的信号通路。该化合物主要应用于缺血/再灌注损伤和登革热休克综合征(DSS)的相关研究。
T4502	BISMUTH SUBGALLATE 次没食子酸铋,Dermatol Puder,Bismuth Gallate	Others	Others
	Bismuth subgallate (Dermatol Puder) 是一种止血剂，可作用于凝血因子 XII ，促使凝血级联的激活，改善纤维蛋白凝块的早期形成。
T19786	Hematin Ferrihemate,Ferriheme hydroxide,Ferriheme,Ferrihemic acid,羟高铁血红素	Others	Others
	Hematin (Ferrihemic acid) 是含铁卟啉，可以结合止血蛋白诱导其失活，降低凝血因子的活性以及阻碍纤维蛋白凝块的溶解。它可用于研究急性卟啉症和癌症。
TP1060	GPRP acetate (67869-62-9 free base) Pefabloc FG,Pefa 6003,GPRP acetate	Others	Others
	GPRP acetate (Pefabloc FG) 是纤维蛋白聚合抑制剂，可抑制纤维蛋白原与血小板膜糖蛋白 Ⅱb/IIIa 复合物(糖蛋白 IIb/IIIa 受体)之间的相互作用。
TP1143L	Fibrinopeptide A, human acetate Fibrinopeptide A, human acetate(25422-31-5 free base),Human fibrinopeptide A acetate	Others	Others
	Fibrinopeptide A, human acetate (Human fibrinopeptide A acetate)(25422-31-5 free base) 是一种 16 个残基的短多肽，由凝血酶从纤维蛋白原上切割下来。纤维蛋白肽 A (FPA) 由纤维蛋白原蛋白的 N 末端 Aα 区域在被凝血酶切割后产生。
TP1736L	Fibrinogen-Binding Peptide fb-acetate Fibrinogen-Binding Peptide （137235-80-4 fb-acetate)	Others	Others
	Fibrinogen-Binding Peptide 137235-80-4(fb-acetate) 是纤维蛋白原受体上玻连蛋白结合位点的推定肽模拟物。它结合纤维蛋白原并抑制血小板与纤维蛋白原的粘附和血小板聚集，还抑制血小板与玻连蛋白的粘附
TP1163	Fibrinopeptide B, human FPB,human
	Fibrinopeptide B (FPB) is produced during the cleavage of fibrinogen, by thrombin, to fibrin monomer.
T78367	Fibrinogen (Bovine)
	Fibrinogen (Bovine)为特异性蛋白质水解酶，通过凝血酶激活过程组装成纤维蛋白凝块。
TP1142	Fibrinopeptide A, human TFA Human fibrinopeptide A TFA
	Fibrinopeptide A, human is a 16-residue short polypeptide cleaved from fibrinogen by thrombin. Fibrinopeptide A, human locates at the NH2-termini of the Aα chain.The conversion of monomeric fibrinogen into polymeric fibrin is mediated by thrombin, which b
TP1736	Fibrinogen-Binding Peptide
	Fibrinogen-Binding Peptide (designed by anticomplementarity hypothesis) is a presumptive peptide mimic of the vitronectin binding site on the fibrinogen receptor. Fibrinogen, a soluble plasma protein, is a cofactor in platelet activation. It is converted
T80682	γ-Fibrinogen 377-395 TFA
	γ-Fibrinogen377-395 TFA 是纤维蛋白原衍生抑制肽，具有纤维蛋白原表位特性。该化合物能在体外抑制小胶质细胞激活、阻断纤维蛋白与Mac-1相互作用，并在小鼠体内抑制实验性自身免疫性脑脊髓炎(EAE)。该肽适用于多发性硬化症(MS)及其他血脑屏障损伤和小胶质细胞激活相关的神经炎症疾病研究。
T80683	γ-Fibrinogen 377-395
	γ-Fibrinogen377-395是一种衍自纤维蛋白原的抑制性肽段，也被认为是纤维蛋白原的表位之一。它能在体外抑制小胶质细胞的激活并阻断纤维蛋白与Mac-1的交互作用；此外，在小鼠体内能够抑制实验性自身免疫性脑脊髓炎(EAE)的发展。因此，γ-Fibrinogen377-395对于多发性硬化症(MS)以及其他与血脑屏障损伤和小胶质细胞活化相关的神经炎症性疾病的研究具有潜在的应用价值。
TP1143	Fibrinopeptide A, human Human fibrinopeptide A
	Fibrinopeptide A, human is a 16-residue short polypeptide cleaved from fibrinogen by thrombin. Fibrinopeptide A (FPA) is produced from the N-terminal Aα region of fibrinogen protein, on cleavage by thrombin.
TP1778	Fibrinogen Binding Inhibitor Peptide
	Fibrinogen Binding Inhibitor Peptide, a synthetic dodecapeptide, represents the specific platelet receptor recognition site of the human fibrinogen g-chain (residues 400-411).
TP1864	[Glu1]-Fibrinopeptide B [Glu1]-纤维蛋白肽B
	[Glu1]-Fibrinopeptide B, a derivative of fibrinopeptide B amino acid residues 1-14, originates from human fibrinopeptide B (hFpB). hFpB is a proteolytic cleavage product of the fibrinogen B beta-chain, specifically generated by thrombin, which plays a significant role in activating neutrophils (PMN), monocytes, and fibroblasts.
TP1162	Fibrinopeptide B, human TFA (36204-23-6 free base) FPB,human TFA,Fibrinopeptide B, human TFA
	FibrinopeptideB,human is a 14-amino acid polypeptide released from the amino terminus of the fibrinogen segment.
T1184	Rivaroxaban BAY 59-7939,利伐沙班	Factor Xa; Thrombin	Metabolism; Proteases/Proteasome
	Rivaroxaban (BAY 59-7939) 是高效选择性的凝血因子 Xa (FXa) 直接抑制剂，IC50=0.7 nM，Ki 为 0.4 nM。
T78215	Dechloro Rivaroxaban	Factor Xa; Others	Metabolism; Others
	Dechloro Rivaroxaban 是一种具有口服活性和高选择性的 Factor Xa 抑制剂。Dechloro Rivaroxaban 对人体内游离 FXa 的抑制作用显著。Dechloro Rivaroxaban 对凝血酶原以及纤维蛋白相关的 FXa 活性也有抑制效果。
T1736	Apixaban 阿哌沙班,BMS-562247-01	Factor Xa	Metabolism
	Apixaban (BMS-562247-01) 是一种高度选择性，可逆的、口服具有活力的凝血因子 Xa (Factor Xa) 抑制剂，抑制人和兔凝血因子 Xa 的 Ki 分别为 0.08 nM 和 0.17 nM。它可以用于研究各种血栓栓塞疾病。
T38736	Nattokinase	Others	Others
	Nattokinase is a powerful fibrinolytic enzyme that effectively hydrolyzes fibrin and plasmin substrate, leading to the breakdown of blood clots. Its efficacy renders it valuable for cardiovascular disease studies.
T35583	Hirudin (54-65; non-sulfated) (trifluoroacetate salt)	Others	Others
	Hirudin (54-65; non-sulfated) is a desulfated peptide fragment of hirudin, an anticoagulant produced byH. medicinalis.1It inhibits fibrin clot formation induced by isolated bovine thrombin with an IC50value of 3.7 μM.2 1.Niehrs, C., Huttner, W.B., Carvallo, D., et al.Conversion of recombinant hirudin to the natural form by in vitro tyrosine sulfation. Differential substrate specificities of leech and bovine tyrosylprotein sulfotransferasesJ. Biol. Chem.265(16)9314-9318(1990) 2.Payne, M.H., Krste...
T82201	H-Gly-Pro-Arg-Pro-NH2
	H-Gly-Pro-Arg-Pro-NH2 是模拟纤维蛋白原(N-末端Gly-Pro-Arg区域)的四肽，具有抑制纤维蛋白聚合的功能。
TP1555	Fibronectin Active Fragment Control
	Fibronectin is a high-molecular weight (~440kDa) extracellular matrix glycoprotein that binds to membrane-spanning receptor proteins called integrins.In addition to integrins, fibronectin also binds extracellular matrix components such as collagen, fibrin
T26657	AR-H067637	Others	Others
	AR-H067637 is a rapid-binding, reversible and potent (inhibition constant K(i) = 2-4 nM), competitive inhibitor of thrombin, as well as of thrombin bound to fibrin (clot-bound thrombin) or to thrombomodulin. The total amount of free thrombin generated in
T25977	Ppack trifluoroacetate Ppack trifluoroacetate salt	Others	Others
	Ppack trifluoroacetate is a peptide derivative that irreversibly and specifically suppresses thrombin-mediated platelet activation by binding with high affinity to the active site of thrombin (Ki: 0.24 nM). It has been utilized as an anticoagulant (100 μM
T62961	ZK824859 hydrochloride	Others	Others
	ZK824859 hydrochloride 是一种选择性的、口服具有活力的尿激酶型纤溶酶原激活剂 (uPA) 抑制剂。ZK824859 hydrochloride 对人 uPA，tPA 和纤溶酶的 IC50 值分别为 79 nM，1580 nM 和 1330 nM。
T80119	Succinyl-(Pro58,D-Glu65)-Hirudin (56-65) (sulfated)	Thrombin	Proteases/Proteasome
	Succinyl-(Pro58,D-Glu65)-Hirudin (56-65) (sulfated) 是一种具有高亲和力的Hirugen类肽，其与凝血酶的KD值小于100 nM。作为抗血栓剂，它能有效抑制凝血酶诱导的纤维蛋白凝块生成，其IC50值为0.087 μM。
T25976	Ppack HCl Ppack dihydrochloride,Fprmecl, dihydrochloride	Others	Others
	Ppack HCl is a peptide derivative that irreversibly and specifically suppresses thrombin-mediated platelet activation by binding with high affinity to the active site of thrombin (Ki: 0.24 nM). It has been utilized as an anticoagulant (100 μM) and to stud
T82286	Glycylglycylcysteine
	Glycylglycylcysteine是一种TAFI抑制剂，其Ki值0.99μM，IC50值为9.4μM，在TAFI底物测定中有效性得以体现。TAFI为一种碱性羧肽酶，通过裂解部分降解纤维蛋白末端的赖氨酸，起到抑制纤维蛋白溶解的功能。
TP2234	coagulation factor II (thrombin) B chain fragment [Homo sapiens]	Others	Others
	Thrombin is a "trypsin-like" serine protease that is encoded by the F2 gene in humans. Thrombin is produced by the enzymatic cleavage of two sites on prothrombin by activated Factor X (Xa). Thrombin in turn acts as a serine protease that converts soluble
T62846	Freselestat quarterhydrate	Others	Others
	Freselestat quarterhydrate (ONO-6818 quarterhydrate) 是一种有效的、口服具有活力的嗜中性粒细胞弹性蛋白酶 (neutrophil elastase) 抑制剂 (Ki: 12.2 nM)。Freselestat quarterhydrate 对其他蛋白酶（例如胰蛋白酶，蛋白酶3，胰弹性蛋白酶，凝血酶，纤溶酶，胶原酶，组织蛋白酶G 和鼠巨噬细胞弹性蛋白酶）的活性低 100 倍以上，表现出有效的抗炎作用。
T78018	Plasminogen
	Plasminogen是一种可由尿激酶血浆蛋白原激活剂(uPA)或组织血浆蛋白原激活剂(tPA)裂解激活的分泌性蛋白，生成血浆蛋白，该酶可以广泛裂解纤维蛋白及其他ECM成分。作为促炎调节剂，Plasminogen能促进急性及糖尿病相关伤口愈合。该蛋白在伤口愈合、炎症和低纤溶酶原血症的研究中有重要应用。
T83663	Mn(III) Protoporphyrin IX Chloride Manganese(III) Protoporphyrin IX Chloride	Others	Others
	Mn(III) protoporphyrin IX chloride是一种金属卟啉，当浓度为10 µM时，能在鸡胚肝细胞中诱导δ-氨基酮戊二酸合成酶和血红素加氧酶(HO)基因的mRNA表达，这些酶分别催化血红素生物合成和降解的限速步骤。Mn(III) protoporphyrin IX chloride含纳米仿生物已被用于体外纤维蛋白凝块的磁共振成像(MRI)研究。此外，它还被用于Mn(III) protoporphyrin IX-6(7)-甘氨酰-甘氨酰-L-组氨酸甲酯(MnGGH)的合成，MnGGH是一种具有微过氧化物酶活性的金属卟啉衍生物。
T36225	N-p-Tosyl-Gly-Pro-Lys-pNA (acetate)	Others	Others
	N-p-Tosyl-Gly-Pro-Lys-pNA is a colorimetric substrate for plasmin.1,2,3Plasmin binds and hydrolyzes N-p-tosyl-Gly-Pro-Lys-pNA to releasep-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as a measure of plasmin activity. 1.Jespersen, J., Gram, J., and Astrup, T.The autodigestion of human plasmin follows a bimolecular mode of reaction subject to product inhibitionThromb. Res.41(3)395-404(1986) 2.Kim, S.H., and Choi, N.S.Electrophoretic analysis of protease inhibitor...

化合物

Cat.No: T78562

Synonym: Fibrin-derived peptide Bβ15-42

Target: Others

BISMUTH SUBGALLATE

Cat.No: T4502

Synonym: 次没食子酸铋,Dermatol Puder,Bismuth Gallate

Target: Others

Cat.No: T19786

Synonym: Ferrihemate,Ferriheme hydroxide,Ferriheme,Ferrihemic acid,羟高铁血红素

Target: Others

GPRP acetate (67869-62-9 free base)

Cat.No: TP1060

Synonym: Pefabloc FG,Pefa 6003,GPRP acetate

Target: Others

Fibrinopeptide A, human acetate

Cat.No: TP1143L

Synonym: Fibrinopeptide A, human acetate(25422-31-5 free base),Human fibrinopeptide A acetate

Target: Others

Fibrinogen-Binding Peptide fb-acetate

Cat.No: TP1736L

Synonym: Fibrinogen-Binding Peptide （137235-80-4 fb-acetate)

Target: Others

Fibrinopeptide B, human

Cat.No: TP1163

Synonym: FPB,human

Fibrinogen (Bovine)

Cat.No: T78367

Fibrinopeptide A, human TFA

Cat.No: TP1142

Synonym: Human fibrinopeptide A TFA

Fibrinogen-Binding Peptide

Cat.No: TP1736

γ-Fibrinogen 377-395 TFA

Cat.No: T80682

γ-Fibrinogen 377-395

Cat.No: T80683

Fibrinopeptide A, human

Cat.No: TP1143

Synonym: Human fibrinopeptide A

Fibrinogen Binding Inhibitor Peptide

Cat.No: TP1778

[Glu1]-Fibrinopeptide B

Cat.No: TP1864

Synonym: [Glu1]-纤维蛋白肽B

Fibrinopeptide B, human TFA (36204-23-6 free base)

Cat.No: TP1162

Synonym: FPB,human TFA,Fibrinopeptide B, human TFA

Cat.No: T1184

Synonym: BAY 59-7939,利伐沙班

Target: Factor Xa, Thrombin

Dechloro Rivaroxaban

Cat.No: T78215

Target: Factor Xa, Others

Cat.No: T1736

Synonym: 阿哌沙班,BMS-562247-01

Target: Factor Xa

Cat.No: T38736

Target: Others

Hirudin (54-65; non-sulfated) (trifluoroacetate salt)

Cat.No: T35583

Target: Others

H-Gly-Pro-Arg-Pro-NH2

Cat.No: T82201

Fibronectin Active Fragment Control

Cat.No: TP1555

Cat.No: T26657

Target: Others

Ppack trifluoroacetate

Cat.No: T25977

Synonym: Ppack trifluoroacetate salt

Target: Others

ZK824859 hydrochloride

Cat.No: T62961

Target: Others

Succinyl-(Pro58,D-Glu65)-Hirudin (56-65) (sulfated)

Cat.No: T80119

Target: Thrombin

Cat.No: T25976

Synonym: Ppack dihydrochloride,Fprmecl, dihydrochloride

Target: Others

Glycylglycylcysteine

Cat.No: T82286

coagulation factor II (thrombin) B chain fragment [Homo sapiens]

Cat.No: TP2234

Target: Others

Freselestat quarterhydrate

Cat.No: T62846

Target: Others

Cat.No: T78018

Mn(III) Protoporphyrin IX Chloride

Cat.No: T83663

Synonym: Manganese(III) Protoporphyrin IX Chloride

Target: Others

N-p-Tosyl-Gly-Pro-Lys-pNA (acetate)

Cat.No: T36225

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T13693	Fibrin	Others	Others
	Fibrin 是血凝块的主要成分，为一种不溶性蛋白质，对凝血过程至关重要。这种蛋白质从牛血中分离出来，特别是在出血时合成。
T3793	(20R)-Ginsenoside Rh1 20(R)-Ginsenoside Rh1,人参皂苷 R-RH1,人参皂苷R-RH1	Others	Others
	(20R)-Ginsenoside Rh1 (20(R)-Ginsenoside Rh1) 是 Ginsenoside Rh1 的 R 型异构体，分离自 Panax Ginseng 中，能够阻碍凝血酶诱导的纤维蛋白原向纤维蛋白的转化。

天然产物

Cat.No: T13693

Target: Others

(20R)-Ginsenoside Rh1

Cat.No: T3793

Synonym: 20(R)-Ginsenoside Rh1,人参皂苷 R-RH1,人参皂苷R-RH1

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-02657	Fibrin Protein, Mouse, Recombinant (His & Myc) Fibin,Fin bud initiation factor homolog	Mouse	Baculovirus Insect Cells
	N/A. Fibrin Protein, Mouse, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 26.5 kDa and the accession number is Q9CQS3.
TMPH-02656	Fibrin Protein, Mouse, Recombinant (E. coli, His & Myc) Fibin,Fin bud initiation factor homolog	Mouse	E. coli
	N/A. Fibrin Protein, Mouse, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 27.6 kDa and the accession number is Q9CQS3.
TMPH-01334	Fibrinopeptide A Protein, Human, Recombinant (His) FGA	Human	E. coli
	Fibrinopeptide A Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 25.1 kDa and the accession number is Q8WW76.
TMPY-05067	Fibrinogen Gamma Chain Protein, Mouse, Recombinant 3010002H13Rik,fibrinogen γ chain,fibrinoge...	Mouse	P. pastoris (Yeast)
	Loss of function mutations in FGG have been associated with fibrinogen deficiency. FGG mRNA was expressed abnormally in HCC and elevated plasma fibrinogen may serve as a useful predictor of clinical progression of HCC patients. Fibrinogen Gamma Chain Protein, Mouse, Recombinant is expressed in yeast. The predicted molecular weight is 30.5 kDa and the accession number is Q3UEM7.
TMPY-04732	Fibrinogen Gamma Chain Protein, Human, Recombinant fibrinogen gamma chain,fibrinogen γ chain,...	Human	P. pastoris (Yeast)
	Loss of function mutations in FGG have been associated with fibrinogen deficiency. FGG mRNA was expressed abnormally in HCC and elevated plasma fibrinogen may serve as a useful predictor of clinical progression of HCC patients. Fibrinogen Gamma Chain Protein, Human, Recombinant is expressed in yeast. The predicted molecular weight is 32.2 kDa and the accession number is P02679-1.
TMPH-00829	Fibrinogen beta chain/FGB Protein, Horse, Recombinant FGB	Horse	E. coli
	Fibrinogen beta chain/FGB Protein, Horse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 53.2 kDa and the accession number is F6PH38.
TMPH-01333	Fibrinogen beta chain Protein, Human, Recombinant (His) Fibrinogen beta chain,FGB	Human	E. coli
	Fibrinogen beta chain Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 54.8 kDa and the accession number is P02675.
TMPH-03722	Coagulase/fibrinolysin Protein, Yersinia pestis, Recombinant (His & Myc) Plasminogen activator,Pla,Coagulase/fibrinolysin	Yersinia pestis	E. coli
	Seems to play an essential role in plague transmission by mediating flea blockage in a temperature-dependent fashion. Fibrinolytic activity prevails at 37 degrees Celsius whereas coagulase expression predominates at lower temperatures (<30 degrees Celsius). Activates plasminogen by cleaving it.
TMPY-02185	Coagulation factor XIII B/F13B Protein, Human, Recombinant (His) Coagulation factor 13,coagulation factor XIII, B polypeptide...	Human	HEK293 Cells
	Coagulation factor XIII B chain, also known as Fibrin-stabilizing factor B subunit, Protein-glutamine gamma-glutamyltransferase B chain, Transglutaminase B chain and F13B, is a secreted protein which contains 1 Sushi ( CCP / SCR ) domains. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have en...
TMPY-05717	Integrin alpha V beta 8 Protein, Human, Recombinant (His) Integrin alpha V β8,Integrin α V β 8	Human	HEK293 Cells
	Integrin alpha V beta 8 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligands. ITGAVB8 does not appear to assume different activation states; and the cytoplasmic tail does not connect to the cytoskeleton. It binds ligands containing an RGD motif; including vitronectin; fibrin and the latency associated peptide (LAP) of the latent TGF-beta complex. High affinity binding of alpha V beta 8 to LAP allows proteolytic cleavage by MT1-MMP; which releases active TGF-beta. This m...
TMPJ-00649	CPB2 Protein, Human, Recombinant (His) CPB2,CPU,TAFI,pCPB,Carboxypeptidase B2,Plasma Carboxypeptida...	Human	HEK293 Cells
	Carboxypeptidase B2 (CPB2) is a secreted enzyme that belongs to the peptidase M14 family. CPB2 is synthesized by the liver and circulates in the plasma as a plasminogen-bound zymogen by the liver and circulates in the plasma as a plasminogen-bound zymogen. CPB2 cleaves C-terminal arginine or lysine residues from biologically active peptides, such as kinins or anaphylatoxins, in the circulation regulating their activities. CPB2 also down-regulates fibrinolysis by removing C-terminal lysine residu...
TMPH-01974	Prothrombin Protein, Human, Recombinant (His) F2,Coagulation factor II,Prothrombin	Human	P. pastoris (Yeast)
	Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing. Prothrombin Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 67.3 kDa and the accession number is P00734.
TMPK-01190	GPVI Protein, Human, Recombinant (His) Glycoprotein 6,Gp6,MGC138168,GPVI	Human	HEK293 Cells
	Although platelets are best known for their role in hemostasis, they are also crucial in development, host defense, inflammation, and tissue repair. Many of these roles are regulated by the immune-like receptors glycoprotein VI (GPVI) and C-type lectin receptor 2 (CLEC-2), which signal through an immunoreceptor tyrosine-based activation motif (ITAM). GPVI is activated by collagen in the subendothelial matrix, by fibrin and fibrinogen in the thrombus, and by a remarkable number of other ligands. ...
TMPJ-00535	F13A Protein, Human, Recombinant (His) F13A1,Coagulation Factor XIII A Chain,Transglutaminase A Cha...	Human	HEK293 Cells
	Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as plasma carrier molecules. Platelet factor XIII is composed of just 2 A subunits, which are identical to those of plasma origin. Upon cleavage of the activation peptide by thrombin and in the presence of calcium io...
TMPH-01508	HABP2 Protein, Human, Recombinant (His & SUMO) Hepatocyte growth factor activator-like protein,Factor VII-a...	Human	E. coli
	Cleaves the alpha-chain at multiple sites and the beta-chain between 'Lys-53' and 'Lys-54' but not the gamma-chain of fibrinogen and therefore does not initiate the formation of the fibrin clot and does not cause the fibrinolysis directly. It does not cleave (activate) prothrombin and plasminogen but converts the inactive single chain urinary plasminogen activator (pro-urokinase) to the active two chain form. Activates coagulation factor VII. May function as a tumor suppressor negatively regulat...
TMPJ-01301	GGACT Protein, Human, Recombinant (His) Gamma-Glutamylaminecyclotransferase,A2LD1,AIG2-Like Domain-C...	Human	E. coli
	Gamma-Glutamylaminecyclotransferase is an enzyme that converts gamma-glutamylamines to free amines and 5-oxoproline which belongs to the gamma-glutamylcyclotransferase family. It shows high activity toward gamma-glutamyl-epsilon-lysine, derived from the breakdown of fibrin and contributes to degradation of proteins cross-linked by transglutaminases. It degrades the cross-link between a lysine and a glutamic acid residue from two proteins that have been cross-linked by transglutaminases. This pro...
TMPK-01302	GPVI Protein, Cynomolgus, Recombinant (His) Glycoprotein 6,MGC138168,GPVI,Gp6	Cynomolgus	HEK293 Cells
	Although platelets are best known for their role in hemostasis, they are also crucial in development, host defense, inflammation, and tissue repair. Many of these roles are regulated by the immune-like receptors glycoprotein VI (GPVI) and C-type lectin receptor 2 (CLEC-2), which signal through an immunoreceptor tyrosine-based activation motif (ITAM). GPVI is activated by collagen in the subendothelial matrix, by fibrin and fibrinogen in the thrombus, and by a remarkable number of other ligands. ...
TMPH-00217	SVMP Protein, Bothrops leucurus, Recombinant (His & Myc) Snake venom metalloproteinase leucurolysin-A	Bothrops leucurus	E. coli
	Non-hemorrhagic metalloproteinase that hydrolyzes the alpha chains of fibrinogen, as well as fibrin, fibronectin and casein. Beta and gamma chains are also hydrolyzed, but more slowly. Thrombolytic activity is also observed. Induces detachment of endothelial cells followed by death, and inhibits endothelial cell adhesion to fibronectin. Induces edema in mouse paw. Inhibits ADP-induced platelet aggregation on human platelet-rich plasma with an IC(50) of 2.8 uM. SVMP Protein, Bothrops leucurus, Re...
TMPJ-01116	HABP2 Protein, Human, Recombinant (His) Factor seven-activating protease,Factor VII-activating prote...	Human	HEK293 Cells
	Hyaluronan-binding protein 2（HABP2） is an extracellular serine protease which binds hyaluronic acid. It secreted as an inactive single-chain precursor and is then activated to a heterodimeric form, which consists of a 50 kDa heavy and a 27 kDa light chain linked by a disulfide bond. HABP2 is involved in cell adhesion, it can cleave the alpha-chain at multiple sites and the beta-chain between 'Lys-53' and 'Lys-54' , but not the gamma-chain of fibrinogen. As a result of this, it does not initiate...
TMPJ-01433	Fibronectin Protein, Human, Recombinant (ED-B domain, Avi & His), Biotinylated Fibronectin,FN1	Human	E. coli
	Fibronectin is a high-molecular weight glycoprotein of the extracellular matrix that binds to membrane-spanning receptor proteins called integrins. Similar to integrins, fibronectin binds extracellular matrix components such as collagen, fibrin, and heparan sulfate proteoglycans. Fibronectin plays a major role in cell adhesion, growth, migration, and differentiation, and it is important for processes such as wound healing and embryonic development. Altered fibronectin expression, degradation, an...
TMPH-00534	Gelatinase Protein, Enterococcus faecalis, Recombinant (His & SUMO) Gelatinase,gelE,Coccolysin	Enterococcus faecalis	E. coli
	Metalloprotease capable of the hydrolysis of insoluble hydrophobic substrates. Hydrolyzes azocoll and gelatin and, at a lower rate, soluble and insoluble collagens. Does not cleave short synthetic peptides. Preferentially hydrolyzes the 24-Phe-\|-Phe-25 bond in the insulin B-chain, followed by the 5-His-\|-Leu-6 bond. Inactivates endothelin-1, primarily by cleavage of the 5-Ser-\|-Leu-6 and 16-His-\|-Leu-17 bonds. Hydrolyzes the alpha chain of C3 to generate a C3b-like protein. Inhibits complement-m...

重组蛋白

Fibrin Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02657

Species: Mouse

Expression System: Baculovirus Insect Cells

Fibrin Protein, Mouse, Recombinant (E. coli, His & Myc)

Cat.No: TMPH-02656

Species: Mouse

Expression System: E. coli

Fibrinopeptide A Protein, Human, Recombinant (His)

Cat.No: TMPH-01334

Species: Human

Expression System: E. coli

Fibrinogen Gamma Chain Protein, Mouse, Recombinant

Cat.No: TMPY-05067

Species: Mouse

Expression System: P. pastoris (Yeast)

Fibrinogen Gamma Chain Protein, Human, Recombinant

Cat.No: TMPY-04732

Species: Human

Expression System: P. pastoris (Yeast)

Fibrinogen beta chain/FGB Protein, Horse, Recombinant

Cat.No: TMPH-00829

Species: Horse

Expression System: E. coli

Fibrinogen beta chain Protein, Human, Recombinant (His)

Cat.No: TMPH-01333

Species: Human

Expression System: E. coli

Coagulase/fibrinolysin Protein, Yersinia pestis, Recombinant (His & Myc)

Cat.No: TMPH-03722

Species: Yersinia pestis

Expression System: E. coli

Coagulation factor XIII B/F13B Protein, Human, Recombinant (His)

Cat.No: TMPY-02185

Species: Human

Expression System: HEK293 Cells

Integrin alpha V beta 8 Protein, Human, Recombinant (His)

Cat.No: TMPY-05717

Species: Human

Expression System: HEK293 Cells

CPB2 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00649

Species: Human

Expression System: HEK293 Cells

Prothrombin Protein, Human, Recombinant (His)

Cat.No: TMPH-01974

Species: Human

Expression System: P. pastoris (Yeast)

GPVI Protein, Human, Recombinant (His)

Cat.No: TMPK-01190

Species: Human

Expression System: HEK293 Cells

F13A Protein, Human, Recombinant (His)

Cat.No: TMPJ-00535

Species: Human

Expression System: HEK293 Cells

HABP2 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01508

Species: Human

Expression System: E. coli

GGACT Protein, Human, Recombinant (His)

Cat.No: TMPJ-01301

Species: Human

Expression System: E. coli

GPVI Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-01302

Species: Cynomolgus

Expression System: HEK293 Cells

SVMP Protein, Bothrops leucurus, Recombinant (His & Myc)

Cat.No: TMPH-00217

Species: Bothrops leucurus

Expression System: E. coli

HABP2 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01116

Species: Human

Expression System: HEK293 Cells

Fibronectin Protein, Human, Recombinant (ED-B domain, Avi & His), Biotinylated

Cat.No: TMPJ-01433

Species: Human

Expression System: E. coli

Gelatinase Protein, Enterococcus faecalis, Recombinant (His & SUMO)

Cat.No: TMPH-00534

Species: Enterococcus faecalis

Expression System: E. coli

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