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Search Results for " dda "

23

抑制剂 & 化合物

11

天然产物

5

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T38534	7-TFA-ap-7-Deaza-ddA
	7-TFA-ap-7-Deaza-ddA (compound 19c, US20060281100A1), a nucleotide derivative, is suitable for synthesizing thiotriphosphate nucleotide dye terminators used in DNA sequencing reactions.
T83765	Dendrogenin A DDA	Others	Others
	Dendrogenin A (DDA) 作为一种选择性肝X受体(LXR)调节剂(SLiM)、胆固醇环氧水解酶(ChEH; Ki = 120 nM)的抑制剂及胆固醇的活性代谢产物，通过DDA合成酶将5,6α-环氧胆固醇与组胺结合形成。DDA在非癌性人乳腺上皮细胞和上皮黑色素细胞中存在，但在多种乳腺癌细胞或黑色素瘤细胞中未发现，且在分离的人乳腺肿瘤组织中仅以低水平存在。它抑制22(R)-羟基胆固醇诱导的LXRβ和LXRα激活(分别以IC50 = 76和362 nM)，但也是LXR的部分激动剂，在B16/F10小鼠黑色素瘤细胞中增加Nur77、NOR-1、LC3-I和LC3-II的蛋白水平。DDA选择性调节LXRα和LXRβ，而非孕烯X受体(PXR)、芳香烃受体(AhR)、维生素D受体(VDR)、维甲酸X受体γ(RXRγ)、维甲酸受体α(RARα)、过氧化物酶体增殖物激活受体α(PPARα)、PPARγ、糖皮质激素受体、雄激素受体、雌激素受体α(ERα)及ERβ在2.5 µM下。此外，DDA在2.5和5 µM的浓度下增加B16/F10和SK-MEL-28癌细胞中LC3-II的蛋白水平，并在2...
T82601	DDa-1	Others	Others
	DDa-1是一种有效的kinase抑制剂，其作用机制是通过（PROTAC）途径促使kinase的降解。
T69631	DDA-tetracycline	Others	Others
	DDA-tetracycline, also known CMT-1 and 4-Des-dimethylaminotetracycline, is a Matrix Metalloproteinase Inhibitor.
T20933	Bis(p-chlorophenyl)acetic acid Bis(p-chlorphenyl)essigsaeure,Bis(4-chlorophenyl)acetic acid,DDA (degradation product),DDA	Others	Others
	Bis(p-chlorophenyl)acetic acid is a standard for pesticide residue analysis.
T64346	DDAC Quaternium 12	Antibacterial	Microbiology/Virology
	DDAC (Quaternium 12), also known as Didecyldimethylammonium chloride, is a dialkyl-quaternary ammonium compound widely utilized in various products due to its bactericidal, virucidal, and fungicidal characteristics.
T15082	DDAO	Others	Others
	DDAO 是有潜在用途的近红外红色荧光探针，其激发波长 (600-650 nm) 和长发射波长 (λem = 656 nm)可以调节。它可用于不同酶活性的检测，如 β-半乳糖苷酶，羧酸酯酶 2，硫酸酯酶，蛋白质磷酸酶 2A，人白蛋白和酯酶。
T11545	hDDAH-1-IN-2	Others	Others
	hDDAH-1-IN-2 is an orally active human dimethylarginine dimethylaminohydrolase-1 (hDDAH-1) inhibitor.
T11552L	hDDAH-1-IN-1 TFA	Others	Others
	hDDAH-1-IN-1 TFA is a selective non-amino acid catalytic site inhibitor of human dimethylarginine dimethylaminohydrolase-1 (hDDAH-1) (Ki: 18 μM).
T125878	Toddacoumaquinone	Others	Others
	Toddacoumaquinone 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T125878。
T10982	ddATP 2',3'-Dideoxyadenosine 5'-triphosphate	Others	Others
	ddATP is a dideoxynucleotide, used as a chain extension inhibitor for DNA polymerase, and used for DNA sequencing by the Sanger method.
T82600	DDAO-C6
	DDAO-C6为酯环酮衍生物，高度特异性荧光探针，专用于检测人血清白蛋白(HSA)。同时，DDAO-C6作为酶激活的近红外荧光探针，适用于通过肠道微生物内源性脂肪酶的活性变化进行目测（Ex/Em=600/658 nm）。
T38532	7-Deaza-7-propargylamino-ddATP	Others	Others
	7-Deaza-7-propargylamino-ddATP, an analog of ddATP, serves as a viable option for gene sequencing purposes due to its chemical composition.
T80746	YYRADDA
	YYRADDA是一种多肽，能够促进皮肤细胞外基质中胶原蛋白的生成，从而改善皮肤外观并促进受损皮肤的恢复。
T29650	ADDA	Others	Others
	ADDA is a non-proteinogenic amino acid existed in toxins produced by cyanobacteria.
T61927	hDDAH-1-IN-2 sulfate	Others	Others
	hDDAH-1-IN-2 是选择性，口服有效的人二甲基精氨酸二甲基氨基水合-1(hDDAH-1)抑制剂，对细胞毒性/活力良好。
T21207	EDDA Ethylenediaminediacetic acid,,AI3-62471	Others	Others
	Ethylenediaminediacetic acid is derived from two molecules of glycine linked by amines.
T11552	hDDAH-1-IN-1	Others	Others
	hDDAH-1-IN-1 is a selective non-amino acid catalytic site inhibitor of human dimethylarginine dimethylaminohydrolase-1 (hDDAH-1) (Ki: 18 μM).
T14126	ADDA 5 hydrochloride	Others	Others
	ADDA 5 hydrochloride is a partial non-competitive inhibitor of cytochrome c oxidase (CcO). For purified CcO from human glioma and bovine heart, the IC50s are 18.93 μM and 31.82 μM , respectively.
T11545L	hDDAH-1-IN-2 sulfate (2408834-77-3 free base) hDDAH-1-IN-2 sulfate	Others	Others
	hDDAH-1-IN-2 sulfate is an orally active human dimethylarginine dimethylaminohydrolase-1 (hDDAH-1) inhibitor.
T25868	Niddamycin F-3463,F 3463,F3463	Others	Others
	Niddamycin is a new macrolide antibiotic.
T25925	p-DDAP pDDAP,p-Dodecylaminophenol	Others	Others
	p-DDAP is an anti-invasive agent that acts by significantly suppressing cell invasion, and the activity and mRNA expression of matrix metalloproteinase-9 (MMP-9).
T36357	Dimethyldioctadecylammonium (bromide)	Others	Others
	Dimethyldioctadecylammonium (DDA) is a cationic amphipathic lipid. DDA liposomes containing an Ag85B-ESAT-6 antigen induce antigen deposition at an intramuscular or subcutaneous injection site in mice, increasing immune cell exposure to the antigen. In a guinea pig model of M. tuberculosis infection, spleen bacterial load is reduced and lung and spleen lesion numbers are decreased when the mycobacterial lipid antigens Ac2SGL and PIM2 are administered in liposomes comprised of DDA and a synthetic...

化合物

7-TFA-ap-7-Deaza-ddA

Cat.No: T38534

Cat.No: T83765

Synonym: DDA

Target: Others

Cat.No: T82601

Target: Others

DDA-tetracycline

Cat.No: T69631

Target: Others

Bis(p-chlorophenyl)acetic acid

Cat.No: T20933

Synonym: Bis(p-chlorphenyl)essigsaeure,Bis(4-chlorophenyl)acetic acid,DDA (degradation product),DDA

Target: Others

Cat.No: T64346

Synonym: Quaternium 12

Target: Antibacterial

Cat.No: T15082

Target: Others

Cat.No: T11545

Target: Others

hDDAH-1-IN-1 TFA

Cat.No: T11552L

Target: Others

Toddacoumaquinone

Cat.No: T125878

Target: Others

Cat.No: T10982

Synonym: 2',3'-Dideoxyadenosine 5'-triphosphate

Target: Others

Cat.No: T82600

7-Deaza-7-propargylamino-ddATP

Cat.No: T38532

Target: Others

Cat.No: T80746

Cat.No: T29650

Target: Others

hDDAH-1-IN-2 sulfate

Cat.No: T61927

Target: Others

Cat.No: T21207

Synonym: Ethylenediaminediacetic acid,,AI3-62471

Target: Others

Cat.No: T11552

Target: Others

ADDA 5 hydrochloride

Cat.No: T14126

Target: Others

hDDAH-1-IN-2 sulfate (2408834-77-3 free base)

Cat.No: T11545L

Synonym: hDDAH-1-IN-2 sulfate

Target: Others

Cat.No: T25868

Synonym: F-3463,F 3463,F3463

Target: Others

Cat.No: T25925

Synonym: pDDAP,p-Dodecylaminophenol

Target: Others

Dimethyldioctadecylammonium (bromide)

Cat.No: T36357

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T4S0592	Toddalolactone (+)-Toddalolactone,飞龙掌血内酯,毛两面针素	PAI-1	Metabolism
	Toddalolactone ((+)-Toddalolactone) 是一种Toddalia asiatica 的主要成分，能够抑制重组人纤溶酶原激活物抑制物-1(PAI-1)的活性， IC50=37.31 μM。
TN5894	Toddanol (-)-Toddanol,(-)-飞龙掌血烯醇内酯	Others	Others
	Toddanol ((-)-Toddanol) 是一种从 Toddalia 根中提取的香豆素。
TN7021	Ent-toddalolactone	Others	Others
	Ent-toddalolactone 是一种天然化合物，属于香豆素类，来源于两面针，具有抗炎、抗癌活性。
TN5888	Toddaculin	Others	Others
	Toddaculin 是一种天然香豆素，抑制过度的破骨细胞活性并增强成骨细胞分化和矿化。它可诱导白血病细胞分化和凋亡，具有抗炎活性。
TN5893	Toddalolactone 3′-O-ethyl ether
	Toddalolactone 3′-O-ethyl ether 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN5893，CAS号为 1538607-30-5。
TN5895	Toddalosin ethyl ether
	Toddalosin ethyl ether 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN5895，CAS号为 1538607-31-6。
TN5150	Toddalosin	Others	Others
	Toddalosin是一种天然产物，属于芸香科飞龙掌血属，其产品编号为 TN5150，CAS号为 137182-37-7。Toddalosin可用作对照参考。
TN5889	(-)-Toddalolactone 3′-O-β-D-glucopyranoside
	(-)-Toddalolactone 3′-O-β-D-glucopyranoside 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN5889，CAS号为 1176645-57-0。
T80969	Toddanone
	Toddanone是从积雪草(Toddalia asiatica)的根部分离出的香豆素类化合物。
T75486	Toddacoumalone	Others	Others
	Toddacoumalone 是一种天然PDE4 (磷酸二酯酶 4) 抑制剂，效力中等，活性分子特性不完善。具有研究银屑病等炎症性疾病潜力。
TN5896	Toddalolactone 3′-O-methyl ether
	Toddalolactone 3′-O-methyl ether 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN5896，CAS号为 143614-35-1。

天然产物

Cat.No: T4S0592

Synonym: (+)-Toddalolactone,飞龙掌血内酯,毛两面针素

Target: PAI-1

Cat.No: TN5894

Synonym: (-)-Toddanol,(-)-飞龙掌血烯醇内酯

Target: Others

Ent-toddalolactone

Cat.No: TN7021

Target: Others

Cat.No: TN5888

Target: Others

Toddalolactone 3′-O-ethyl ether

Cat.No: TN5893

Toddalosin ethyl ether

Cat.No: TN5895

Cat.No: TN5150

Target: Others

(-)-Toddalolactone 3′-O-β-D-glucopyranoside

Cat.No: TN5889

Cat.No: T80969

Cat.No: T75486

Target: Others

Toddalolactone 3′-O-methyl ether

Cat.No: TN5896

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-00524	ATP-dependent DNA helicase dda Protein, Enterobacteria phage T4, Recombinant (His) ATP-dependent DNA helicase dda,dda,sud	Enterobacteria phage T4	E. coli
	DNA helicase that stimulates viral DNA replication and recombination. Plays a role in T4 DNA replication initiation by selecting and activating DNA origins. Acts by dissociating and reassociating with the DNA molecule being unwound. Unwinds DNA as a monomer in a 5'-to-3' direction at a rate of 250 bp/s and can efficiently displace proteins from the DNA. ATP-dependent DNA helicase dda Protein, Enterobacteria phage T4, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. T...
TMPH-01220	DDA1 Protein, Human, Recombinant (His) Placenta cross-immune reaction antigen 1,DET1- and DDB1-asso...	Human	E. coli
	Functions as a component of numerous distinct DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. In the DCX complexes, acts as a scaffolding subunit required to stabilize the complex. DDA1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 17.7 kDa and the accession number is Q9BW61.
TMPH-01732	DDAH1 Protein, Human, Recombinant (His & Myc) DDAHI,N(G),N(G)-dimethylarginine dimethylaminohydro...	Human	E. coli
	Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation. DDAH1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 38.4 kDa and the accession number is O94760.
TMPH-01733	DDAH2 Protein, Human, Recombinant (GST & His) Inactive dimethylarginine dimethylaminohydrolase 2,DDA	Human	E. coli
	Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation. DDAH2 Protein, Human, Recombinant (GST & His) is expressed in E. coli expression system with N-6xHis-GST tag. The predicted molecular weight is 61.2 kDa and the accession number is O95865.
TMPH-00528	Recombination and repair protein Protein, Enterobacteria phage T4, Recombinant (His) UVSX,Recombination and repair protein	Enterobacteria phage T4	E. coli
	Important in genetic recombination, DNA repair, and replication. Possesses pairing and strand-transfer activity. Interacts with dda and gene 32 proteins.

重组蛋白

ATP-dependent DNA helicase dda Protein, Enterobacteria phage T4, Recombinant (His)

Cat.No: TMPH-00524

Species: Enterobacteria phage T4

Expression System: E. coli

DDA1 Protein, Human, Recombinant (His)

Cat.No: TMPH-01220

Species: Human

Expression System: E. coli

DDAH1 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01732

Species: Human

Expression System: E. coli

DDAH2 Protein, Human, Recombinant (GST & His)

Cat.No: TMPH-01733

Species: Human

Expression System: E. coli

Recombination and repair protein Protein, Enterobacteria phage T4, Recombinant (His)

Cat.No: TMPH-00528

Species: Enterobacteria phage T4

Expression System: E. coli

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