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Search Results for " choline acetyltransferase "

Targets Recommended: AChE

5

抑制剂 & 化合物

2

天然产物

2

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T14194	β-NETA α-NETA	AChE	Neuroscience
	β-NETA(α-NETA) 是胆碱乙酰转移酶(ChA；IC50=76 μM) 和胆碱酯酶 (ChE;IC50=40 µM)的非竞争性抑制剂，对乙酰胆碱酯的作用微弱 (AChE;IC50=1 mM)。
T29203	Zanapezil fumarate TAK 147,TAK147,TAK-147	Others	Others
	Zanapezil is an acetylcholinesterase (AChE) inhibitor. Zanapezil increases choline acetyltransferase activity in cultured rat septal cholinergic neurons.
T13975	ZSET-845	Others	Others
	ZSET-845 is an enhancer of cognitive which enhances choline acetyltransferase activity in the hippocampus in the rat.
T4497L	Amifampridine phosphate BRN0110232,3,6-DAP,SC10,BRN 0110232,BRN-0110232,NSC 521760	Others	Others
	Amifampridine is mainly used to treat many rare muscle diseases. In the United States, aminopyridine is being studied for the treatment of Lambert-Eaton myasmus syndrome (LEMS). Amifampridine is also used to treat many congenital myasthenia syndromes, par
T61454	α-NETA	Others	Others
	α-NETA是一种有效的胆碱乙酰转移酶(ChA)非竞争性抑制剂，IC50值为9μM。同时，它也是ALDH1A1(IC50=0.04μM)和趋化因子样受体1(CMKLR1)的有效拮抗剂。此外，α-NETA对胆碱酯酶(ChE; IC50=84μM)和乙酰胆碱酯酶(AChE; IC50=300μM)的抑制作用较弱。α-NETA亦显示出抗癌活性。

化合物

Cat.No: T14194

Synonym: α-NETA

Target: AChE

Zanapezil fumarate

Cat.No: T29203

Synonym: TAK 147,TAK147,TAK-147

Target: Others

Cat.No: T13975

Target: Others

Amifampridine phosphate

Cat.No: T4497L

Synonym: BRN0110232,3,6-DAP,SC10,BRN 0110232,BRN-0110232,NSC 521760

Target: Others

Cat.No: T61454

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T3767	Polygalacic acid Virgaureagenin G,毛果一枝黄花皂苷元G,远志酸	MMP; AChR; AChE	Neuroscience; Proteases/Proteasome
	Polygalacic acid (Virgaureagenin G) 是一种从远志 Polygala tenuifolia Willd 根中分离出来的三萜，可抑制 MMP 表达。它对认知障碍有显著的神经保护作用，PA 通过抑制乙酰胆碱酯酶活性，增加胆碱乙酰转移酶活性，提高海马和额皮质中的乙酰胆碱水平来提高胆碱能系统反应性。它可以用于骨关节炎相关研究。
T29963	Americanol A
	Americanol A enhances choline acetyltransferase activity; has neurotrophic properties.

天然产物

Polygalacic acid

Cat.No: T3767

Synonym: Virgaureagenin G,毛果一枝黄花皂苷元G,远志酸

Target: MMP, AChR, AChE

Cat.No: T29963

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-01085	CHAT Protein, Human, Recombinant (His) CHAT,Choline O-acetyltransferase,ChAT,CHOA...	Human	E. coli
	Catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses. CHAT Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 72.7 kDa and the accession number is P28329.
TMPY-00146	RKIP/PEBP1 Protein, Human, Recombinant PBP,HEL-S-34,PEBP,RKIP,HCNP,PEBP-1,phosphatidylethanolamine ...	Human	E. coli
	Phosphatidylethanolamine-binding protein 1 (PEBP1), also known as Raf kinase inhibitor protein, belongs to PEBP family of proteins. It is known to interact with many proteins that are mainly involved in pathways that monitor cell proliferation and differentiation. PEBP1 in many cells interacts with several pathways, namely MAPK, GRK2, NF-small ka, CyrillicB, etc. that keeps the cell proliferation and differentiation in check. This protein is expressed by many cells in humans, including neurons w...

重组蛋白

CHAT Protein, Human, Recombinant (His)

Cat.No: TMPH-01085

Species: Human

Expression System: E. coli

RKIP/PEBP1 Protein, Human, Recombinant

Cat.No: TMPY-00146

Species: Human

Expression System: E. coli

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