Azido-PEG3-NHSester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Azido-PEG3-O-NHSester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Azido-PEG3-aminoacetic acid-NHSester is a PEGylation-based linker for the development of PROTACs[1]. It can be utilized in the synthesis of PROTACs, offering a versatile and efficient approach.
Azido-PEG3-SS-NHS is a three-unit polyethylene glycol (PEG) linker functionalized with an azide group, a cleavable disulfide bond, and an N-hydroxysuccinimide ester. It is primarily employed in the synthesis of antibody-drug conjugates (ADCs) [1].
Azido-PEG3-MS is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
(E)-TCO-PEG4-NHSester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Propargyl-PEG2-NHSester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Mal-amido-PEG2-NHSester is a noncleavable linker for antibody-drug conjugates (ADCs) that consists of a maleimide group and an NHSester. The NHSester allows for the labeling of protein primary amines (-NH2), amine-modified oligonucleotides, and other amine-containing molecules[1][2].
Azido-PEG8-NHSester is an 8 unit PEG linker with cleavable properties, commonly employed in the synthesis of antibody-drug conjugates (ADCs)[1]. This compound also serves as a PEG- and Alkyl ether-based PROTAC linker, enabling its utilization in the synthesis of PROTACs[2].
Mal-PEG2-NHSester is a noncleavable antibody-drug conjugate linker comprising a Maleimide moiety, a 2-unit PEG spacer, and an N-hydroxysuccinimide (NHS) ester functionality.
m-PEG11-NHSester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Biotin-PEG6-NHSester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Azido-PEG3-Sulfone-PEG4-acid is a polyethylene glycol (PEG) derivative frequently employed as a linker in the construction of proteolysis targeting chimeras (PROTACs)[1].
m-PEG15-NHSester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
N-DBCO-N-bis(PEG2-C2-NHSester) is a Polyethylene Glycol (PEG) derived linker that finds utility in the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].