67
16
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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T0776 |
Phenothiazine
ENT 38,吩噻嗪 |
Dopamine Receptor; Antibacterial; Antibiotic; Antifungal | GPCR/G Protein; Microbiology/Virology; Neuroscience |
Phenothiazine (ENT 38) 是一种抗生素,具有杀虫,抗菌,驱虫和杀真菌活性。它也可研究神经系统疾病。 | |||
T1546 |
Nitazoxanide
NSC 697855,硝唑尼特 |
Others; Influenza Virus; Parasite; Autophagy | Autophagy; Microbiology/Virology; Others |
Nitazoxanide (NSC-697855) 是一种广谱驱虫剂,对感染动物和人类的各种蠕虫、原生动物和肠道细菌都具有作用活性。 它在无菌培养中抑制Giardia lamblia 滋养体增殖,IC50为 2.4 μM。它可研究寄生虫性胃肠炎,具有抗病毒特性。 | |||
T19807 |
Dithiazanine iodide
Delvex,Telmide,Vercidon,Abminthic,Netocyd,NSC 221154 |
Others | Others |
Dithiazanine iodide (Netocyd) 是一种苯并噻唑。它已被用作抗虫剂。它作为纳米颗粒在治疗胶质母细胞瘤方面也很有效。 | |||
T0237 |
Closantel
氯氰碘柳胺,R-31520,氯生太尔 |
Antibacterial; Parasite | Microbiology/Virology |
Closantel (R-31520) 是抗寄生虫活性的卤化水杨酰苯胺。它是高度特异性盘尾丝虫几丁质酶抑制剂。 | |||
T6452 |
Closantel Sodium
|
Antibacterial; Parasite | Microbiology/Virology |
Closantel sodium 是抗寄生虫活性的卤化水杨酰苯胺。它是高度特异性的盘尾丝虫几丁质酶抑制剂。 | |||
T7901 |
Emodepside
Bay 44-4400 |
Parasite | Microbiology/Virology |
Emodepside (Bay 44-4400) 是一种对多种胃肠道线虫有效的驱虫药,具有广谱驱虫活性。 | |||
T10850L |
CMP-5 2HCl
|
Others | Others |
CMP-5 2HCl 是一种驱虫剂。CMP-5 2HCl 体外抗H. contortus 的EC100为5μM。 | |||
T7887 |
8-Hydroxyquinoline hemisulfate
8-羟基喹啉硫酸盐,Oxyquinoline sulfate |
Others; Antibacterial; Antibiotic | Microbiology/Virology; Others |
8-Hydroxyquinoline hemisulfate (Oxyquinoline sulfate) 是一种单质子双齿螯合剂,具有温和的抑菌、驱虫和杀螨作用。 | |||
T16126 |
Monepantel
AAD1566,PPL-1 |
AChR | Neuroscience |
Monepantel (AAD1566) 是一种有机驱虫剂,也是来自蛔虫和食管造口的烟碱乙酰胆碱受体拮抗剂,广泛用于农牧业除虫。 | |||
T1343L |
Crystal Violet
Methyl Violet 10B,Hexamethylpararosaniline chloride,氯化结晶紫,Basic Violet 3,结晶紫,Gentian Violet |
DNA; Influenza Virus; Antibacterial | DNA Damage/DNA Repair; Microbiology/Virology |
Crystal Violet (Hexamethylpararosaniline chloride) 是革兰氏染色染料。它对H1N1具有抗病毒作用,有显著杀菌活性。 | |||
T7605 |
Avermectin B1a
阿维菌素 B1a,Abamectin B1a,Avamectin B1a |
Antibiotic; Parasite | Microbiology/Virology |
Avermectin B1a 是能够使线虫瘫痪的一种抗寄生虫剂。 | |||
T20082 |
Dymanthine
十八烷基二甲基叔胺,Adogen 342D,ADMA 18 |
Others | Others |
Dymanthine (ADMA 18) 是驱虫药,对多种肠道蠕虫感染具有潜在的研究价值。 | |||
T7146 |
Piperazine adipate
|
Parasite | Microbiology/Virology |
Piperazine adipate 是一种广谱驱虫剂,可抵抗哺乳动物中很多常见的寄生虫感染。 | |||
T30819 |
CGP 20376
CGP-20376,CGP20376 |
Others | Others |
CGP 20376 是一种苯并噻唑化合物,是一种驱虫剂,对嗜酸性粒细胞呼吸爆发的双重剂量依赖性调节体外作用,具有抗纤特性。 | |||
T0714 |
Oxfendazole
奥吩达唑,奥芬哒唑,RS-8858 |
Glucokinase; Microtubule Associated; Parasite | Cytoskeletal Signaling; Metabolism; Microbiology/Virology |
Oxfendazole (RS-8858) 是fenbendazole 的亚砜形式,是广谱苯并咪唑驱虫剂,可保护牲畜免受蛔虫、圆线虫和蛲虫的侵害。 | |||
T15272 |
Febantel
|
Parasite | Microbiology/Virology |
Febantel 是一种用于家禽和家畜的蛔虫、绦虫感染的驱虫剂。 | |||
T16539 |
Piperazine citrate
|
GABA Receptor | Membrane transporter/Ion channel; Neuroscience |
Piperazine citrate 是一种六元环化合物,有驱虫的作用。 | |||
T0395 |
Pyrantel tartrate
Banminth,酒石酸噻吩嘧啶 |
Antibiotic; Parasite | Microbiology/Virology |
Pyrantel tartrate (Banminth) 是一种四氢嘧啶类广谱牲畜驱虫剂,是烟碱乙酰胆碱受体激动剂。它能引起寄生虫的痉挛性肌肉麻痹。它可研究胃肠道线虫感染。 | |||
T5836 |
Eprinomectin
依普菌素,MK-397 |
Parasite | Microbiology/Virology |
Eprinomectin (MK-397) 是一种阿维菌素,具有驱虫,杀虫杀螨活性。 | |||
T6372 |
Albendazole sulfoxide
Ricobendazole,Albendazole Oxide,阿苯达唑亚砜 |
Microtubule Associated; Parasite | Cytoskeletal Signaling; Microbiology/Virology |
Albendazole sulfoxide (Ricobendazole) 是一种驱虫药阿苯达唑的代谢物,有抗寄生虫活性。 | |||
T30596 |
Brotianide
BAY-VA 4059,Dirian,BAY-VA-4059,BAY-VA4059 |
Parasite | Microbiology/Virology |
Brotianide (BAY-VA4059) 具有驱虫活性,对肝吸虫和胃吸虫侵染具有很高的效力,可用于治疗绵羊的急性、亚急性和慢性肝脏法氏囊病感染。 | |||
T77684 |
4-(2-Aminoethyl)amino-7-chloroquinoline
N1-(7-Chloroquinolin-4-yl)ethane-1,2-diamine |
Parasite | Microbiology/Virology |
4-(2-Aminoethyl)amino-7-chloroquinoline (N1-(7-Chloroquinolin-4-yl)ethane-1,2-diamine) 具有潜在的抗虫和抗肿瘤活性,可用于研究疟疾。 | |||
T0955 |
Oxyclozanide
Oxiclozanidum,Zanil,Oxyclozanid,Zanilox,氯羟柳胺 |
Antibiotic; Parasite | Microbiology/Virology |
Oxyclozanide (Oxyclozanid) 是一种水杨酰苯胺驱虫药,用于放牧动物的片形吸虫和绦虫感染。 | |||
T77507 |
(-)-Benzotetramisole
|
Others | Others |
(-)-Benzotetramisole 使一种高效且具有选择性的催化剂。(-)-Benzotetramisole 是抗蠕虫化合物四咪唑3 的苯annulated 衍生物,本身也是转化的有效催化剂。 | |||
T77643 |
2-(Chloromethyl)Imidazo[1,2-A]Pyridine
|
Others | Others |
2-(Chloromethyl)imidazo[1,2-a]pyridine 具有潜在的抗虫活性,可用于合成有活性的化合物。 | |||
T7093 |
Rafoxanide
碘醚柳胺,雷复尼特 |
CDK; Parasite | Cell Cycle/Checkpoint; Microbiology/Virology |
Rafoxanide 是口服活性水杨酰苯胺类驱虫剂。它作为抗寄生虫剂,可用于控制羊和牛的 Hemonchus 种和 Fasciola 种的感染。 | |||
T62769 |
Tribendimidine
|
AChR | Neuroscience |
Tribendimidine 是一种广谱的、口服具有活力的驱虫剂,也是一种 L 型烟碱乙酰胆碱受体 (nAChR) 激动剂。Tribendimidine 对 A. lumbricoides 和 N. americanus 具有极高的活性。 | |||
T1420 |
Diethylcarbamazine citrate
Caritrol,枸橼酸乙胺嗪,Loxuran,Dicarocide |
Lipoxygenase; COX; Parasite | Immunology/Inflammation; Metabolism; Microbiology/Virology; Neuroscience |
Diethylcarbamazine citrate (Caritrol) 是驱肠虫药,主要用作治疗丝虫病的柠檬酸盐,是丝虫微丝蚴的花生四烯酸代谢抑制剂。 | |||
T0009 |
Flubendazole
氟苯咪唑,Flumoxanal,Flumoxane,NSC 313680,Fluvermal |
Apoptosis; Microtubule Associated; Parasite | Apoptosis; Cytoskeletal Signaling; Microbiology/Virology |
Flubendazole (Flumoxane) 是用于治疗人类蠕虫感染的驱虫药。它通过抑制微管功能等机制发挥抗癌作用。它诱导p53介导的细胞凋亡,抑制 G2/M 细胞周期。 | |||
T37072 |
Nitroxynil
4-Hydroxy-3-iodo-5-nitrobenzonitrile,Trodax,Dovenix |
Parasite | Microbiology/Virology |
Nitroxynil (4-Hydroxy-3-iodo-5-nitrobenzonitrile) 为一种广泛用于研究 Fasciola hepatica 感染的驱虫剂,有效作用于寄生虫的成熟及未成熟阶段。 | |||
T0066 |
Dichlorophen
双氯酚,DDM,Dichlorophene |
Antibacterial; Parasite; Antifungal | Microbiology/Virology |
Dichlorophen (DDM) 是一种抗微生物剂,对绦虫,原生动物,真菌和细菌具有活性,通过增加肠道内容物的清除,消除肠道中的绦虫感染。 | |||
T4059 |
Selamectin
UK-124114,司拉克丁,塞拉菌素 |
Chloride channel; P-gp; Parasite | Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience |
Selamectin (UK-124114) 是半合成的大环内酯,是一种驱虫剂,可增强线虫中谷氨酸和 GABA 门控氯离子通道的开放。它还是抗寄生虫剂,可激活神经元和咽肌中的谷氨酸门控氯离子通道,以预防恶丝虫,淋巴丝虫和线虫感染。它还是 P-糖蛋白底物和抑制剂,IC50为 120 nM。 | |||
T0124 |
UK-124114
UNII-A2669OWX9N,西拉菌素,Selamectin |
Others | Others |
UK-124114 (Selamectin) 是伊维菌素的大环内酯衍生物,伊维菌素是一种驱虫剂,可增强线虫中谷氨酸和 GABA 门控氯离子通道的开放。在 H. contortus 幼虫发育试验中,赛拉菌素 (0.1 µg/ml) 显示出生长抑制作用。 | |||
T25188 |
Butonate
NSC17872,NSC 17872,NSC-17872 |
Others | Others |
Butonate is an Anthelmintic agent. | |||
T0323L |
Oxantel
|
Others | Others |
Oxantel is a fumarate reductase inhibitor with anthelmintic activity. | |||
T34567 |
Sch 18099
Sch-18099,Sch18099 |
Others | Others |
Sch 18099 showed anthelmintic activity. | |||
T30968 |
Clioxanide
Tremerad,SYD-230,SYD 230,Clioxanida,Clioxanidum |
Others | Others |
Clioxanide is an anthelmintic agent. | |||
T21473 |
Naftalofos
Naftalofosum,Rawetin,Maretin,Rametin,Naphthalophos |
Others | Others |
Naftalofos is an anthelmintic and an insecticide. | |||
T34236 |
R 7-45
R 7/45,R7-45,R-7-45 |
Others | Others |
R 7-45 is an organic arsenical that acts as an anthelmintic agent. | |||
T21476 |
Niclofolan
Niclofolano,Bilevon M,Menichlopholan,ME-3625,Niclofolanum |
Others | Others |
Niclofolan, a biphenyl anthelmintic compound, is used orally towards the treatment of Fasciola hepatica infection. | |||
T15462 |
Haloxon
|
Others | Others |
Haloxon is an organophosphorus anthelmintic. Haloxon is used against nematodes of the abomasum and small intestine in ruminants. | |||
T13770 |
Melarsonyl
Melarsonic acid |
Others | Others |
Melarsonyl (Melarsonic acid) can inhibit parasite potently. Melarsonyl (Melarsonic acid) is an anthelmintic agent. | |||
T20825 |
Diethylcarbamazine
RP3799,Diaethylcarbamazinum,AI3-19612,RP 3799,Bitirazine,RP-3799 |
Others | Others |
Diethylcarbamazine, an anthelmintic, is used primarily as the citrate in the treatment of filariasis, particularly infestations with Loa loa or Wucheria bancrofti. | |||
T34876 |
Ticarbodine
EL-974,EL 974,EL974 |
Others | Others |
Ticarbodine(EL-974)is an Anthelmintic agent. | |||
T26679 |
Atelocantel
AH 353623,AH-353623,AH353623 |
Others | Others |
Atelocantel is an anthelmintic agent (veterinary drug). | |||
T20624 |
Bitriben
Chloxyl,Cloxil,Fluorescent Red Mega 485 NHS-ester,Chloksil,Chloxil |
Others | Others |
Bitriben is an agent with the anthelmintic effect. | |||
T38729 |
Melarsonyl dipotassium
美拉胂钾,Melarsonic acid dipotassium |
Others | Others |
Melarsonyl dipotassium, also known as melarsonic acid dipotassium, is a potent anthelmintic agent with the ability to effectively inhibit parasites. | |||
T20960 |
Luxabendazole
HOE 216V |
Others | Others |
Luxabendazole is a benzimidazole carbamate broad-spectrum anthelmintic agent. It has proved to be effective against immature and adult stages of the major gastrointestinal nematodes, cestodes, and trematodes. | |||
T33690 |
Nitroscanate
Lopatol,CGA-23654GS,CGA 23654 |
Others | Others |
Nitroscanate is an anthelmintic found to be effective in certain strains of parasites in canines. | |||
T21226 |
Albendazole sulfone
|
Others | Others |
Albendazole sulfone, a metabolite of Albendazole, is an antibiotic, anthelmintic, and antiparisitic. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T0314 |
Hexylresorcinol
己雷锁辛,4-己基间苯二酚,4-Hexylresorcinol |
Apoptosis; Tyrosinase; Antibacterial; Parasite | Apoptosis; Microbiology/Virology; Proteases/Proteasome |
Hexylresorcinol (4-Hexylresorcinol) 是在植物中发现的一种天然产物,具有抗菌、驱虫、防腐和抗肿瘤活性。它是一种可逆、非竞争性的 α-葡萄糖苷酶抑制剂,有抗 DNA 氧化损伤的保护作用。它可诱导鳞癌细胞凋亡。 | |||
T8193 |
α-Thujone
Thujone,ALPHA-(-)-THUJONE,α-侧柏酮,(-)-α-侧柏酮 |
Apoptosis; Reactive Oxygen Species; GABA Receptor; AChR; Parasite; Autophagy | Apoptosis; Autophagy; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Neuroscience; NF-κB |
α-Thujone 是一种从西方金钟柏精油中分离出来的单萜,可穿透血脑屏障。它是 GABAA 受体的可逆调节剂,在抑制 GABA 诱导的电流时,它的 IC50为 21 μM。它诱导 ROS 依赖性细胞毒性,还诱导细胞凋亡和自噬。它具有抗伤害,抗肿瘤、杀虫和驱虫活性。 | |||
T0956 |
Avermectin B1
Avermectin B1a-Avermectin B1b mixt.,Abamectin,阿维菌素 |
Antibiotic; Parasite; Autophagy | Autophagy; Microbiology/Virology |
Avermectin B1 是驱虫杀虫剂。 | |||
T25114 |
Ascaridole
NSC-406266,NSC 406266,NSC406266 |
Parasite | Microbiology/Virology |
Ascaridole (NSC-406266) 可作为驱虫化合物,能驱除人体和植物中的寄生蠕虫(蠕虫),具有较弱的抗疟活性。 | |||
TN6718 |
Dehydrocostuslactone
|
Others | Others |
Dehydrocostuslactone 是一种从奥克兰提取的天然产物。它具有广泛的生物作用,包括抗炎、抗癌、抗病毒、抗菌、抗真菌、抗氧化、抗糖尿病、抗溃疡和驱虫活性。 | |||
T3S0006 |
(E)-Ferulic acid methyl ester
Methyl ferulate,Methyl (E)-ferulate,(E)-阿魏酸甲酯 |
IL Receptor; p38 MAPK; TNF; COX; NO Synthase; JNK; Antifection | Apoptosis; Immunology/Inflammation; MAPK; Microbiology/Virology; Neuroscience |
(E)-Ferulic acid methyl ester (Methyl (E)-ferulate) 具有较强 DPPH 和 ABTS+自由基清除特性。 | |||
TN2324 |
Yuankanin
|
Antioxidant | oxidation-reduction |
Yuankanin 是一种是在百里香叶、Daphne gnidium 和Daphne feddei 中发现的天然化合物,是一种 genkwanin-5-bioside,具有抗虫和抗氧化活性并对o- 1葡萄糖苷酶、脂肪酶、胰蛋白酶和黄嘌呤氧化酶具有抑制作用。 | |||
T1157 |
Moxidectin
milbemycin B,CL301423,莫昔克丁,莫西菌素 |
GluCls; Antibiotic; Parasite | Microbiology/Virology |
Moxidectin (CL301423) 是可用于预防和控制心丝虫和蛔虫的一种驱虫剂。 | |||
T38675 |
Hikizimycin
Anthelmycin |
Others | Others |
Hikizimycin is a potent anthelmintic and antibacterial natural product. | |||
T16497 |
PF 1022A
|
Others | Others |
PF 1022A is an N-methylated cyclooctadepsipeptides with strong anthelmintic properties. It also acts as an ionosphere. | |||
T38235 |
16-Keto Aspergillimide
|
Others | Others |
16-Keto Aspergillimide (SB202327) is a novel anthelmintic compound derived from the Aspergillus strain IMI 337664. | |||
T35908 |
Paraherquamide E
|
Others | Others |
Paraherquamide E is a fungal metabolite originally isolated from P. charlesii with anthelmintic and insecticidal activities. It is lethal to C. elegans (LD50 = 6 μg/ml). Paraherquamide E is also lethal to O. fasciatus (LD50 = 0.089 μg/nymph). Oral administration of paraherquamide E (0.5-4 mg/kg) reduces T. colubriformis fecal egg count in gerbils. | |||
T82706 |
Clonostachydiol
|
||
Clonostachydiol为源于真菌Clonostachys cylindrospora(菌株FH-A 6607)的大分子内酯类驱虫药。 | |||
TN4639 |
Neolitsine
|
Others | Others |
Neolitsine has anthelmintic activity, it exhibits EC90 values (concentration at which 90% loss of larval motility is observed) of 6.4 microg/mL.Neolitsine and dicentrine have potent vasorelaxing effects on precontracted rat aortic preparations with mean IC 50 values between 0.08 and 2.48 microM. | |||
T75494 |
Shinjulactone M
|
Others | Others |
Shinjulactone M 是一种从 Ailanthus 中分离出来的一种苦木苦味素类化合物。Ailanthus 可用作退热药 (抗疟) 和驱虫药,用于慢性支气管炎、癫痫和哮喘的研究。 | |||
T37609 |
(rel)-Asperparaline A
|
Others | Others |
Aspergillimide is a fungal metabolite originally isolated from A. japonicus.1 It reduces nicotinic acetylcholine receptor (nAChR) peak and slowly-desensitizing amplitudes induced by acetylcholine in silkworm (B. mori) larval neurons (IC50s = 20.2 and 39.6 nM, respectively) but has no effect on chicken α3β4-, α4β2-, and α7-containing nAChRs.2 Dietary administration of aspergillimide A (10 μg/g of diet) induces paralysis in silkworm fourth instar larvae.1 Aspergillimide A (10 and 20 mg/kg) reduces... |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-03035 |
M-myrmeciitoxin-Mp2b Protein, Myrmecia pilosula, Recombinant (GST & His)
DELTA-myrtoxin-Mp1a B chain,Pilosin-3 subunit b,M-myrmeciito... |
Myrmecia pilosula | Baculovirus Insect Cells |
Heterodimer protein that may serve both defensive (pain-inducing) and predatory (insecticidal) roles. Has membrane-disrupting activity and shows induction of non-specific calcium influx into cells,. Shows broad-spectrum activity against a diverse range of bacteria, and cell lines, as well as hemolytic activity (EC(50)=2.18 uM). In vivo, shows moderate insecticidal activity against D.melanogaster and potent anthelmintic activity against the veterinary nematode H.contortus. In addition, intraplant... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T19527 |
Praziquantel D11
吡喹酮 D11 |
Others | Others |
Praziquantel D11 is the deuterium labeled Praziquantel, and is an agent of anthelmintic. | |||
T19184 |
Albendazole sulfoxide D3
Albendazole oxide D3,Ricobendazole D3 |
Others | Others |
Albendazole sulfoxide D3 is deuterium-labeled Albendazole sulfoxide. Albendazole sulfoxide is a broad-spectrum anthelmintic. | |||
TMIJ-0489 |
Coumaphos-d10
|
||
Coumaphos-d10 是 Coumaphos 的氘代化合物。Coumaphos 的 CAS 号为 56-72-4。 | |||
TMIJ-0295 |
Flubendazole-d3 (methyl-d3)
|
||
Flubendazole-d3 (methyl-d3) 是 Flubendazole 的氘代化合物。Flubendazole 的 CAS 号为 31430-15-6。Flubendazole 是用于治疗人类蠕虫感染的驱虫药。它通过抑制微管功能等机制发挥抗癌作用。它诱导p53介导的细胞凋亡,抑制 G2/M 细胞周期。 | |||
T71055 |
Albendazole-d7
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Albendazole-d7 is intended for use as an internal standard for the quantification of albendazole by GC- or LC-MS. Albendazole is an orally bioavailable benzimidazole anthelmintic that is active against a variety of helminths, including liver flukes, tapeworms, and roundworms. It eliminates Trichostrongylus in the fourth stomach of cattle and sheep when orally administered at doses ranging from 2.5 to 10 mg/kg as well as other species in the fourth stomach and the small and large intestine. Alben... |