32
2
1
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T20898 |
(R)-Propranolol hydrochloride
Dexpropranolol hydrochloride,(R)-(+)-Propranolol,盐酸普奈洛尔 |
Adrenergic Receptor | GPCR/G Protein; Neuroscience |
(R)-Propranolol hydrochloride (Dexpropranolol hydrochloride) 是一种抗肾上腺素受体拮抗剂,是一种普萘洛尔的活性较低的对映体。Dexpropranolol 是一种非选择性的β-adrenergic receptor 拮抗剂,对 β1AR 和 β2AR 具有高亲和力。 | |||
T4560 |
Alprenolol
Alpheprol,阿普洛尔,(RS)-Alprenolol,dl-Alprenolol |
5-HT Receptor; Adrenergic Receptor | GPCR/G Protein; Neuroscience |
Alprenolol (Alpheprol) 是一种非选择性β受体阻滞剂,也是5-HT1A 受体拮抗剂。 | |||
T22236 |
Alprenolol hydrochloride
阿普洛尔盐酸盐,盐酸阿普洛尔 |
5-HT Receptor | GPCR/G Protein; Neuroscience |
Alprenolol hydrochloride 是一种非选择性β受体阻滞剂,也是5-HT1A 受体拮抗剂。 | |||
T1239 |
Indacaterol maleate
马来酸茚达特罗,QAB149 |
Adrenergic Receptor | GPCR/G Protein; Neuroscience |
Indacaterol maleate (QAB149) 是一种超长效的 β-肾上腺素受体激动剂。 | |||
T30846 |
CGP-20712
UNII-SIO2UEZ19H,CGP 20712 |
Adrenergic Receptor | GPCR/G Protein; Neuroscience |
CGP-20712 是一种具有选择性的 β 1-肾上腺素受体拮抗剂,IC50 为 0.7 nM。 | |||
T30027 |
Amosulalol
|
Adrenergic Receptor | GPCR/G Protein; Neuroscience |
Amosulalol 是一种 α 和 β 肾上腺素能受体拮抗剂。 | |||
T26081L |
Ridazolol HCl
CAS 413 |
Adrenergic Receptor | GPCR/G Protein; Neuroscience |
Ridazolol HCl (CAS 413) 是一种新型β-肾上腺素受体 (β-AR) 阻滞剂,具有α-肾上腺素溶解活性。 | |||
T21411 |
Isoproterenol
Norisodrine,Isoprenaline,Novodrin,Isuprel,Medihaler-Iso |
Endogenous Metabolite; Adrenergic Receptor | GPCR/G Protein; Metabolism; Neuroscience |
Isoproterenol (Norisodrine) 是一种非选择性且具有口服活性的 β-肾上腺素受体激动剂。Isoproterenol 是有效的外周血管扩张剂和支气管扩张剂。Isoproterenol 可用于研究心动过缓和支气管哮喘,用于治疗心脏传导阻滞、心动过缓。 | |||
T5028 |
Landiolol hydrochloride
ONO-1101 hydrochloride,盐酸兰地洛尔 |
Adrenergic Receptor | GPCR/G Protein; Neuroscience |
Landiolol hydrochloride (ONO-1101 hydrochloride) 是一种肾上腺素能受体拮抗剂,是一种 beta1 高选择性的超短作用β- 阻断剂(β1 /β2 选择性 = 255:1, 半衰期 4 分钟)。 | |||
T10364 |
Arbutamine
GP 21213 |
Adrenergic Receptor | GPCR/G Protein; Neuroscience |
Arbutamine (GP 21213) 是一种新型非选择性β-肾上腺素受体激动剂,具有α-1-拟交感神经活性。Arbutamine 促进心脏应激,增加心率、心脏收缩力。Arbutamine 可用于研究心脏应激和冠状动脉疾病。 | |||
T8580 |
Bupranolol
|
Adrenergic Receptor | GPCR/G Protein; Neuroscience |
Bupranolol 是竞争性的、口服活性的、非选择性的β-adrenoceptor 拮抗剂,无固有的拟交感神经活性。 | |||
T1282 |
Carteolol hydrochloride
Arteoptic,Abbott-43326,OPC-1085 hydrochloride,盐酸卡替洛尔,Carteolol HCl,Mikelan |
Adrenergic Receptor | GPCR/G Protein; Neuroscience |
Carteolol hydrochloride (Abbott-43326) 是一种非选择性的β肾上腺素受体阻断剂。 | |||
T0324 |
Isoxsuprine hydrochloride
Duvadilan,Isolait,盐酸异克舒令,盐酸苯氧丙酚胺 |
Adrenergic Receptor; iGluR | GPCR/G Protein; Membrane transporter/Ion channel; Neuroscience |
Isoxsuprine hydrochloride (Isolait) 是 β 肾上腺素受体激动剂和NMDA 受体拮抗剂,对子宫肌层和胎盘的 β 肾上腺素受体的Ki 值分别为 13.65 和 3.48 μM。 | |||
T10302 |
Amibegron hydrochloride
SR 58611A |
Others | Others |
Amibegron hydrochloride is a selective β3-adrenoceptor agonist (EC50: 3.5 nM for β-adrenoceptor in rat colon). It has anxiolytic and antidepressant activity. | |||
T13465 |
(+)-Penbutolol
(+)-Isopenbutolol,(R)-Penbutolol |
Others | Others |
(+)-Penbutolol is an antagonist of β-adrenoceptor(IC50 of 0.74 μM). (+)-Penbutolol is an optical isomer of l-penbutolol with Na+ channel-blocking action. | |||
T22699 |
Cyanopindolol hemifumarate
|
Others | Others |
5-HT1A/1B antagonist and β-adrenoceptor antagonist | |||
T24448 |
MEN935
Adimolol hydrochloride hydrate,MEN-935,Men 935 |
Others | Others |
MEN935 is an antihypertensive agent. It is also a β-adrenoceptor blocker. | |||
T23343 |
SDZ 21009
|
Others | Others |
β-adrenoceptor and 5-HT1A/1B receptor antagonist | |||
T68835 |
Mindodilol
|
Others | Others |
Mindodilol is a β-adrenoceptor blocker and vasodilator. | |||
T13982 |
(±)-Befunolol
|
Others | Others |
(±)-Befunolol is a blocking agent of β-adrenoceptor. | |||
T68930 |
Milveterol
|
Others | Others |
Milveterol is a long-acting β(2)-adrenoceptor agonist. | |||
T71931 |
Clencyclohexerol
|
Others | Others |
Clencyclohexerol is an analog of clenbuterol. β-Adrenoceptor agonists, including clenbuterol, modulate protein synthesis and degradation and have therapeutic potential in muscle wasting disorders. β-adrenoceptor agonists have deleterious cardiovascular side effects when used systemically and at high concentrations. | |||
T61577 |
Sulfinalol
|
Others | Others |
Sulfinalol为口服活性β-肾上腺素受体(β-adrenoceptor)拮抗剂,具备直接血管扩张功能。 | |||
T11608 |
Epanolol
Visacor,ICI141292 |
Others | Others |
Epanolol is a potent β-adrenoceptor partial agonist with a greater affinity for β1- than β2-adrenoceptors. | |||
T70194 |
AM92016
|
Others | Others |
AM92016 is a specific blocker of the time dependent delayed rectifier potassium current. AM92016 does not show any β-adrenoceptor blocking activity. | |||
T61138 |
Bevantolol
|
Others | Others |
Bevantolol, a selective β-1 adrenoceptor antagonist, is utilized for the investigation of angina pectoris and hypertension [1]. | |||
T11786 |
KUL-7211 racemate
KUL 7211 racemate |
Adrenergic Receptor | GPCR/G Protein; Neuroscience |
KUL 7211 is a selective β-adrenoceptor agonist. KUL 7211 racemate is the racemate of KUL 7211. | |||
T61918 |
Ro 363 hydrochloride
|
Others | Others |
Ro 363 hydrochloride 是一种有效的,高度选择性的 β1 肾上腺素受体 (β1-adrenoceptor) 激动剂。Ro 363 hydrochloride 是有效的正性肌力活化剂。Ro 363 hydrochloride 是心血管调节剂,可降低舒张压,显著增加心肌收缩力。 | |||
T10812 |
Cicloprolol hydrochloride
|
Adrenergic Receptor | GPCR/G Protein; Neuroscience |
Cicloprolol hydrochloride 是一种新型有效且具有选择性的 β1-肾上腺素能受体 (β 1-adrenoceptor) 拮抗剂,具有部分激动剂活性,可用于研究冠心病。 | |||
T5450 |
DL-071-IT
Afurolol Hydrochloride,DL 071 IT |
Adrenergic Receptor | GPCR/G Protein; Neuroscience |
DL-071-IT (Afurolol Hydrochloride) 是一种有效的非选择性β-肾上腺素受体拮抗剂。 DL-071-IT 表现出内在的拟交感神经活性和弱的膜稳定活性。 | |||
T63356 |
Bopindolol fumarate
|
Others | Others |
Bopindolol ((±)-Bopindolol) fumarate 是一种具有部分激动剂活性的、口服具有活力的 β-肾上腺素受体 (ARs) 拮抗剂,对 β1- 和 β2-ARs 无选择性,对 β3-AR 亚型亲和力低。Bopindolol fumarate 是 Pindolol 的前体药物,能够用于研究原发性和肾血管性高血压。 | |||
T22872 |
Isamoltane hemifumarate
|
Others | Others |
5-HT1B antagonist |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T3158 |
Harmane
Loturine,Harman,Aribine,哈尔满碱 |
Adrenergic Receptor; Monoamine Oxidase; Imidazoline Receptor | GPCR/G Protein; Neuroscience |
Harmane (Loturine) 是一种在咖啡和烟草烟雾中发现的 β-咔啉生物碱,是有效的神经毒素,可引起严重的动作震颤和精神病学表现。它还是选择性的单胺氧化酶抑制剂,具有致突变作用,对 MAO A/B 的 IC50值分别为 0.5 和 5 μM。 | |||
T2889 |
Isoferulic acid
Isoferulate,Hesperetic acid,3-Hydroxy-4-methoxycinnamic acid,Hesperetate,异阿魏酸 |
Influenza Virus; Adrenergic Receptor | GPCR/G Protein; Microbiology/Virology; Neuroscience |
Isoferulic acid (Hesperetate) 是一种肉桂酸衍生物,有抗糖尿病活性和抗流感病毒活性。它能结合并激活 α1-肾上腺素能受体,增强 β-内啡肽的分泌并增加体外葡萄糖的使用。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T12550 |
Propranolol-d7 hydrochloride
Propranolol D7 hydrochloride |
Others | Others |
Propranolol D7 hydrochloride is a deuterium labeled Propranolol hydrochloride. Propranolol hydrochloride is a nonselective antagonist of β-adrenergic receptor (βAR). |