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Search Results for " use disorders "

Targets Recommended: Potassium Channel MRP Adrenergic Receptor ABC Autophagy

10

抑制剂 & 化合物

2

天然产物

2

化合物库

1

同位素标记化合物

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Cat. No.	Product Name
L2520	糖代谢化合物库		702 compounds
	702 种糖代谢相关的化合物，可用于高通量和高内涵筛选；
L2560	代谢化合物库		2320 compounds
	2320 种代谢途径相关的化合物，可用于高通量和高内涵筛选。

化合物库

糖代谢化合物库

Cat.No: L2520

Compounds: 702

代谢化合物库

Cat.No: L2560

Compounds: 2320

Cat. No.	Product Name	Target	Signaling Pathways
T1050	Prazosin hydrochloride Prazosin hydrochloride,哌唑嗪盐酸盐,Prazosin HCl,cp-12299-1,Peripress,Vasoflex,盐酸哌唑嗪,Minipress	Potassium Channel; MRP; Adrenergic Receptor; ABC; Autophagy	Autophagy; GPCR/G Protein; Immunology/Inflammation; Membrane transporter/Ion channel; Neuroscience
	Prazosin hydrochloride (Vasoflex) 是一种选择性肾上腺素能 α-1 拮抗剂，可降低外周阻力并放松血管平滑肌。它可用于研究高血压和酒精使用障碍。它是一种合成哌嗪衍生物，具有降压抗肾上腺素能特性。它抑制有机阳离子转运蛋白 OCT-1 和 OCT-3，IC50分别为 1.8 和 13 μM 。
T0098	Ipratropium bromide monohydrate Ipratropium bromide hydrate,溴化异丙托品单水合物	AChR	Neuroscience
	Ipratropium bromide monohydrate (Ipratropium bromide hydrate) 是一种毒蕈碱拮抗剂，结构上与阿托品相关，但它通常被认为对吸入使用更安全、更有效。它用于各种支气管疾病、鼻炎和抗心律失常。
T2270	Trans-Tranilast Tranilast trans-,反式-曲尼司特,反-曲尼司特	RAAS	Endocrinology/Hormones
	Trans-Tranilast 是抗过敏剂，可用于过敏性鼻炎、支气管哮喘和特应性皮炎的研究。
T27623	Ipsapirone hydrochloride BAY q 7821,BAY q-7821,BAY q7821,Ipsapirone HCl	Others	Others
	Ipsapirone, a pyrimidinylpiperazine ligand, is potent and specific for 5-HT1A receptors and has potential therapeutic use in affective disorders.
T69025	Ipratropium Free Base	Others	Others
	Ipratropium Free Base is a muscarinic antagonist structurally related to ATROPINE but often considered safer and more effective for inhalation use. It is used for various bronchial disorders, in rhinitis, and as an antiarrhythmic.
T13428	(5R)-BW-4030W92	Sodium Channel	Membrane transporter/Ion channel
	(5R)-BW-4030W92是 R 型的 BW-4030W92 ，是具有活性的对映体。(5R)-BW-4030W92 是一种可口服的非选择性、电压依赖性和使用依赖性的钠离子通道 (sodium channel) 拮抗剂，可用于研究神经系统疾病。
T73455	Ph-HTBA	Others	Others
	Ph-HTBA 是CaMKIIα的高亲和力、脑穿透调节剂。Ph-HTBA 对 CaMKIIα 具有结合亲和力，Kd 值为 757 nM。Ph-HTBA 可用于缺血和神经退行性疾病的研究。
T84399	UWA-101 hydrochloride	Others	Others
	UWA-101 hydrochloride是一种选用性强、无细胞毒性的DAT/SERT抑制剂，对DAT和SERT的EC50值分别为3.6 µM和2.3 µM。该化合物能降低多巴胺能活性分子（例如L-DOPA）的副作用（如运动障碍），且不具有精神活性特性。UWA-101 hydrochloride适用于神经退行性疾病（如帕金森病）的相关研究。
T36760	KQMEEEAVRLFIEWLKNGGPSSGAPPPS	Others	Others
	KQMEEEAVRLFIEWLKNGGPSSGAPPPS is a Exendin-4 peptide derivative. Exendin-4 is a pure GLP-1 receptor agonist. Exendin-4 peptide derivatives are structurally derived from Exendin-4 and may relates to dual GLP-1/glucagon receptor agonists. Their medical use, for example in the treatment of disorders of the metabolic syndrome, including diabetes and obesity, as well as for reduction of excess food intake. These dual GLP-1/glucagon receptor agonists show reduced activity on the GIP receptor to reduce ...
T38178	Ristocetin A (sulfate) Ristomycin III	Others	Others
	Ristocetin A, a glycopeptide related to vancomycin, is an antibiotic produced by the microorganism Nocardia lurida[1]. Ristocetin A is currently in clinical use to treat bacterial infections [1]. Ristocetin A is an antibiotic which can be used to treat staphylococcal infections. The side effects of ristocetin A include thrombocytopenia and platelet agglutination. Ristocetin A has been used in two assays: the ristocetin cofactor assay and the ristocetin-induced platelet aggregation assay. These t...

化合物

Prazosin hydrochloride

Cat.No: T1050

Synonym: Prazosin hydrochloride,哌唑嗪盐酸盐,Prazosin HCl,cp-12299-1,Peripress,Vasoflex,盐酸哌唑嗪,Minipress

Target: Potassium Channel, MRP, Adrenergic Receptor, ABC, Autophagy

Ipratropium bromide monohydrate

Cat.No: T0098

Synonym: Ipratropium bromide hydrate,溴化异丙托品单水合物

Target: AChR

Trans-Tranilast

Cat.No: T2270

Synonym: Tranilast trans-,反式-曲尼司特,反-曲尼司特

Target: RAAS

Ipsapirone hydrochloride

Cat.No: T27623

Synonym: BAY q 7821,BAY q-7821,BAY q7821,Ipsapirone HCl

Target: Others

Ipratropium Free Base

Cat.No: T69025

Target: Others

(5R)-BW-4030W92

Cat.No: T13428

Target: Sodium Channel

Cat.No: T73455

Target: Others

UWA-101 hydrochloride

Cat.No: T84399

Target: Others

KQMEEEAVRLFIEWLKNGGPSSGAPPPS

Cat.No: T36760

Target: Others

Ristocetin A (sulfate)

Cat.No: T38178

Synonym: Ristomycin III

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T6S1966	Curculigoside Curculigoside A,仙茅苷	Antioxidant; NF-κB; JAK; STAT	Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; NF-κB; oxidation-reduction; Stem Cells
	Curculigoside (Curculigoside A) 是仙茅中的主要皂苷，具有显著的抗氧化、抗骨质疏松、抗抑郁和神经保护作用。它通过调节JAK/STAT/NF-κB 信号传导途径，具有抗关节炎作用。
T21296	Desmopressin acetate trihydrate Desmogalen,Adiuretin,Deamino Arginine Vasopressin,Vasopressin 1-Desamino-8-arginine
	Desmopressin acetate is a synthetic replacement for vasopressin, which reduces urine production. Medical use of Desmopressin acetate includes: (a) bed wetting; (b) diabetes insipidus; (c) nighttime urination; (d) clotting disorders.

天然产物

Cat.No: T6S1966

Synonym: Curculigoside A,仙茅苷

Target: Antioxidant, NF-κB, JAK, STAT

Desmopressin acetate trihydrate

Cat.No: T21296

Synonym: Desmogalen,Adiuretin,Deamino Arginine Vasopressin,Vasopressin 1-Desamino-8-arginine

Cat. No.	Product Name	Target	Signaling Pathways
T35698	Octanoic Acid-13C
	Octanoic acid-13C is intended for use as an internal standard for the quantification of octanoic acid by GC- or LC-MS. Octanoic acid is a medium-chain saturated fatty acid. It has been found in Teleme cheeses made from goat, ovine, or bovine milk.1 Octanoic acid is active against the bacteria S. mutans, S. gordonii, F. nucleatum, and P. gingivalis (IC80s = <125, <125, 1,403, and 2,294 μM, respectively).2 Levels of octanoic acid are increased in the plasma of patients with medium-chain acyl-CoA d...

同位素标记化合物

Octanoic Acid-13C

Cat.No: T35698

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