thalidomide 4fluoride

Thalidomide 4-fluoride (E3 ligase Ligand 4) 是一种基于 Thalidomide 的 Cereblon 配体，可用于募集 CRBN 蛋白。它能够利用 linker 与 IRAK4 靶蛋白配体连接，得到 PROTAC IRAK4 degrader-1。

Thalidomide-4-OH (E3 ligase Ligand 2) 是一种基于 Thalidomide 的 Cereblon 配体，可用于募集 CRBN 蛋白。它能够利用 linker 与靶蛋白配体连接，得到 PROTAC 分子。

Thalidomide 5-fluoride (H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-5-fluoro-) 是一种基于沙利度胺的 Cereblon 配体，通过 linker 与 IRAK4 蛋白配体结合形成 PROTACIRAK4 degrader-1。

Thalidomide 4'-ether-alkylC2-amine hydrochloride (halidomide-linker 6) 包含基于 Thalidomide 的 cereblon 配体和 linker，是合成的 E3 连接酶配体-linker 偶联物，可应用于 PROTAC 技术。

Functionalized cereblon ligand for PROTAC research and development; incorporates an E3 ligase ligand plus an alkylC1-PEG3-alkylC3 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

Thalidomide-4-O-C12-NH2 hydrochloride为基于Thalidomide的cereblon配体，能够招募CRBN蛋白。该化合物可利用linker与目标蛋白配体结合，构建PROTAC分子，如THAL-SNS-032。

Thalidomide-4-O-C11-NH2 hydrochloride是Thalidomide衍生的cereblon配体，能够募集CRBN蛋白。该化合物能够利用linker与目标蛋白配体结合，进而形成PROTAC分子，如THAL-SNS-032。

Thalidomide4'-ether-PEG1-azide 是一种以Thalidomide为基础，能够募集CRBN蛋白的cereblon配体。通过linker与靶蛋白配体连接，Thalidomide4'-ether-PEG1-azide可用于形成PROTAC分子。

Thalidomide-Piperazine 5-fluoride hydrochloride，作为Thalidomide衍生物，是一种cereblon(CRBN)抑制剂，用作E3 泛素连接酶的配体(Ligands for E3 Ligase)，适用于PROTACs合成。

Functionalized cereblon ligand for PROTAC research and development; incorporates an E3 ligase ligand plus a short PEG linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was Thalidomide - linker 11 PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

Thalidomide-Piperazine 5-fluoride is a compound developed by synthesizing an E3 ligase ligand-linker conjugate. It incorporates a cereblon ligand derived from Thalidomide and utilizes a linker commonly employed in PROTAC technology.

Functionalized cereblon ligand for PROTAC research and development; incorporates an E3 ligase ligand plus an alkylC8 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was Thalidomide amide-alkylC8-amine PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

Thalidomide-4-C3-NH2 hydrochloride is a Thalidomide-derived cereblon ligand utilized for the recruitment of CRBN protein. This compound can be linked to the ligand for protein using a linker to create PROTACs.

Thalidomide-4-O-C10-NH2 hydrochloride 是一种Thalidomide衍生的cereblon配体，能募集CRBN蛋白。该化合物可利用linker与特定的靶蛋白配体结合，用以构建PROTAC分子，如THAL-SNS-032。

Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride consists of a cereblon (CRBN) ligand for the E3 ubiquitin ligase and a linker, making it suitable for PROTACs design.

Thalidomide-4-O-C7-NH2 hydrochloride是一种Thalidomide衍生的CRBN配体，能够招募cereblon蛋白。该化合物能通过linker与目标蛋白配体结合，用于构建PROTAC分子，如THAL-SNS-032。

Thalidomide-4-O-C14-NH2 hydrochloride是一款衍生于Thalidomide的cereblon配体，能够招募CRBN蛋白。该化合物通过linker可与目标蛋白的配体结合，进而构建PROTAC分子，例如THAL-SNS-032。