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Search Results for " technical grade "
Targets Recommended: Others

2

抑制剂 & 化合物

1

天然产物

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Cat. No. Product Name Target Signaling Pathways
T35817 Photoswitchable PAD Inhibitor (technical grade)

Others Others
Photoswitchable PAD inhibitor is a photoactivated protein arginine deiminase (PAD) inhibitor and a derivative of BB-Cl-amidine that contains an azobenzene photoswitch allowing optical control of PAD activity.1 Without photoactivation, it is a weak inhibitor of PAD2 (IC50 = >100 μM) and is less potent than BB-Cl-amidine in inhibiting citrulline production in vitro (kinact/KIs = 2,300, 600, 1,000, and 10,510 M-1min-1 for PAD1-4, respectively) and does not inhibit histone H3 citrullination in HEK29...
T36108 YW3-56 (hydrochloride) (technical grade)

YW3-56 (hydrochloride) (technical grade)

Others Others
YW3-56 is an inhibitor of protein arginine deiminase 2 (PAD2) and PAD4 (IC50s = 0.5-1 and 1-5 μM, respectively).1It inhibits the growth of U2OS osteosarcoma cells (IC50= ~2.5 μM) in a p53-dependent mannerviainduction of SESN2 and subsequent inhibition of mTORC1. YW3-56 (10 mg/kg) reduces tumor growth in an S-180 murine sarcoma tumor model. It also inhibits tumor growth in the 1883 MDA-MB-231 breast cancer bone metastasis mouse xenograft model.2 1.Wang, Y., Li, P., Wang, S., et al.Anticancer pept...

化合物

Photoswitchable PAD Inhibitor (technical grade)
Cat.No: T35817
Synonym:
Target: Others
YW3-56 (hydrochloride) (technical grade)
Cat.No: T36108
Synonym: YW3-56 (hydrochloride) (technical grade)
Target: Others
Cat. No. Product Name Target Signaling Pathways
TN2440 Sinapyl alcohol

NOS; COX Immunology/Inflammation; Neuroscience
Sinapyl alcohol 是来自 Magnolia sieboldii 的天然产物

天然产物

Sinapyl alcohol
Cat.No: TN2440
Synonym:
Target: NOS, COX
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