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Targets Recommended: Glucocorticoid Receptor

5

抑制剂 & 化合物

2

天然产物

5

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T1163 Betamethasone valerate

Betnovate,倍他米松戊酸酯,Betaderm,Betamethasone 17-valerate,Luxiq

Glucocorticoid Receptor Endocrinology/Hormones
Betamethasone valerate (Luxiq) 的 17 戊酸酯,是一种具有抗炎活性的局部皮质类固醇。它能够抑制放射标记的糖皮质激素地塞米松与人表皮(IC50:5 nM)及小鼠皮肤(IC50:6 nM)的结合。它可用于研究复发性口疮。
TP1429 VSV-G Peptide acetate(103425-05-4 free base)

VSV-G Peptide

Others Others
VSV-G Peptide acetate(103425-05-4 free base) 是一种 11 个氨基酸的肽,来源于水疱性口炎病毒糖蛋白。
TP2191 VSV-G Peptide

Others Others
VSV-G is a vesicular stomatitis virus G (VSV-G) protein fragment. VSV-G protein is commonly used in biomedical research to pseudotype retroviral and lentiviral vectors, conveying the ability to transduce a broad range of mammalian cell types with genes of
T75768 VSV-G tag Peptide

Others Others
VSV-G Peptide 是一种源于水泡性口炎病毒糖蛋白的由 11 个氨基酸残基组成的多肽。
T84494 (-)-Neplanocin A

Others Others
S-Adenosylhomocysteine (SAH) hydrolase is responsible for the reversible hydrolysis of SAH into adenosine and homocysteine. Inhibition of this enzyme leads to the accumulation of SAH within cells, thereby increasing the SAH to S-adenosylmethionine (SAM) ratio and subsequently inhibiting SAM-dependent methyltransferases. (−)-Neplanocin A, a potent and irreversible inhibitor of SAH hydrolase (Ki= 8.39 nM), exhibits significant antitumor activity against mouse leukemia L1210 cells and holds broad-s...

化合物

Betamethasone valerate
Cat.No: T1163
Synonym: Betnovate,倍他米松戊酸酯,Betaderm,Betamethasone 17-valerate,Luxiq
Target: Glucocorticoid Receptor
VSV-G Peptide acetate(103425-05-4 free base)
Cat.No: TP1429
Synonym: VSV-G Peptide
Target: Others
VSV-G Peptide
Cat.No: TP2191
Synonym:
Target: Others
VSV-G tag Peptide
Cat.No: T75768
Synonym:
Target: Others
(-)-Neplanocin A
Cat.No: T84494
Synonym:
Target: Others
Cat. No. Product Name Target Signaling Pathways
TN7238L Sanguinarine citrate

Sanguinarium citrate,Sanguinarin citrate,Pseudochelerythrine citrate

Antibiotic Microbiology/Virology
Sanguinarine citrate (Pseudochelerythrine chloride) 是一种来源于 Sanguinaria Canadensis 的生物碱,具有抗菌、抗炎和镇痛活性,可用于治疗口腔炎、牙龈出血和喉炎等口腔炎症疾病 。
T75570 Justicidin C

Others Others
Justicidin C 是一种抗病毒木脂素,对水泡性口炎病毒展现了较强的抗病毒活性,同时在兔肺细胞(RL-33)中显示较低的细胞毒性。

天然产物

Sanguinarine citrate
Cat.No: TN7238L
Synonym: Sanguinarium citrate,Sanguinarin citrate,Pseudochelerythrine citrate
Target: Antibiotic
Justicidin C
Cat.No: T75570
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPH-00842 p63 Protein, Human, Recombinant (His)

Transformation-related protein 63,Tumor protein 63,Keratinoc...

Human E. coli
p63 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 80.8 kDa and the accession number is Q9H3D4.
TMPH-02127 SNX16 Protein, Human, Recombinant (His)

Sorting nexin-16,SNX16

Human E. coli
May be involved in several stages of intracellular trafficking. Plays a role in protein transport from early to late endosomes. Plays a role in protein transport to the lysosome. Promotes degradation of EGFR after EGF signaling. Plays a role in intracellular transport of vesicular stomatitis virus nucleocapsids from the endosome to the cytoplasm.
TMPH-01902 DDX60 Protein, Human, Recombinant (His)

Probable ATP-dependent RNA helicase DDX60,DEAD box protein 6...

Human E. coli
Positively regulates DDX58/RIG-I- and IFIH1/MDA5-dependent type I interferon and interferon inducible gene expression in response to viral infection. Binds ssRNA, dsRNA and dsDNA and can promote the binding of DDX58/RIG-I to dsRNA. Exhibits antiviral activity against hepatitis C virus and vesicular stomatitis virus (VSV). DDX60 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 23.1 kDa and the accession number is Q8IY2...
TMPH-02855 PML Protein, Mouse, Recombinant (His & Myc)

Protein PML,Pml

Mouse E. coli
Functions via its association with PML-nuclear bodies (PML-NBs) in a wide range of important cellular processes, including tumor suppression, transcriptional regulation, apoptosis, senescence, DNA damage response, and viral defense mechanisms. Acts as the scaffold of PML-NBs allowing other proteins to shuttle in and out, a process which is regulated by SUMO-mediated modifications and interactions. Positively regulates p53/TP53 by acting at different levels (by promoting its acetylation and phosp...
TMPH-01248 ADAR Protein, Human, Recombinant (His & SUMO)

ADAR1,IFI-4,136 kDa double-stranded RNA-binding protein,Inte...

Human E. coli
Catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) referred to as A-to-I RNA editing. This may affect gene expression and function in a number of ways that include mRNA translation by changing codons and hence the amino acid sequence of proteins; pre-mRNA splicing by altering splice site recognition sequences; RNA stability by changing sequences involved in nuclease recognition; genetic stability in the case of RNA virus genomes by changing sequences duri...

重组蛋白

p63 Protein, Human, Recombinant (His)
Cat.No: TMPH-00842
Species: Human
Expression System: E. coli
SNX16 Protein, Human, Recombinant (His)
Cat.No: TMPH-02127
Species: Human
Expression System: E. coli
DDX60 Protein, Human, Recombinant (His)
Cat.No: TMPH-01902
Species: Human
Expression System: E. coli
PML Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02855
Species: Mouse
Expression System: E. coli
ADAR Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01248
Species: Human
Expression System: E. coli
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