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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T2437 |
O4I2
O-4I2,O4I2 |
OCT | Membrane transporter/Ion channel |
O4I2 是一种 Oct3/4诱导剂,可增强多能干细胞相关基因 Lin28、Sox2和 Nanog 的表达,并抑制 Rex1。 | |||
T82630 |
CysOx2
|
||
CysOx2为磺胺酸反应基荧光探针(Ex/Em: 394/535nm),专用于检测活细胞内蛋白质半胱氨酸氧化情况。 | |||
T63196 |
DS17701585
|
Others | Others |
DS17701585 是口服具有活力的、选择性的EP300和CBP 抑制剂,能够作用于 CBP (IC50: 0.040 μM)、EP300 (IC50: 0.15 μM)、H3K27 (IC50: 0.45 μM)和SOX2 (IC50: 0.7 μM),能够用于研究癌症。 | |||
T60661 |
CP681301
|
Others | Others |
CP681301 是CDK5的有效抑制剂,具有抗增殖活性。CP681301 在果蝇中表现出抗肿瘤活性。CP681301 降低神经胶质瘤干细胞中 CD133、OLIG2、SOX2、KI67、pCDK5 蛋白水平的表达。CP681301 减少小鼠胶质瘤异种移植物的自我更新。 | |||
T1271 |
Pronetalol
|
Others | Others |
Pronethalol ((±)-Pronethalo) 是一种非选择性的 β-肾上腺素 (β-adrenergic) 拮抗剂。 Pronethalol 是 Sox2表达的有效抑制剂。Pronethalol 可预防和逆转洋地黄引起的室性心律失常,并限制脑动静脉畸形 (AVMs)。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-00008 |
SOX-2 Protein, Human, Recombinant (His)
SOX2,Transcription factor SOX- |
Human | E. coli |
SOX-2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 38.4 kDa and the accession number is P48431. | |||
TMPH-01895 |
POU5F1 Protein, Human, Recombinant (B2M & His)
Octamer-binding protein 4,Octamer-binding protein 3,POU5F1,O... |
Human | E. coli |
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 or SOX15 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency. POU5F1 Protein, Human, Recombinant (B2M & His) is expressed in E. coli expression system with N-6xHis-B2M tag. The predicted molecular weight is 52.6 kDa and the accession number is Q... |